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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

response to hypoxia

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

proteolysis

The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

tissue remodeling

The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

response to oxygen levels

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.

all

NA

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

response to hypoxia

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

cell surface

The external part of the cell wall and/or plasma membrane.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

sodium channel complex

An ion channel complex through which sodium ions pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

serine-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.

serine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

exopeptidase activity

Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

peptidase activity, acting on L-amino acid peptides

Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

monovalent inorganic cation transmembrane transporter activity

Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

symporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

serine hydrolase activity

Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

serine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

serine-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

Id	Pvalue	ExpCount	Count	Size	Term
GO:0007588	4.062e-07	0.9889	11 AQP3, ATP6V0A4, CLDN16, DAB2, KCNJ1, KCNK5, NPHS2, NPR3, SCNN1A, SCNN1B, SCNN1G	24	excretion
GO:0015672	2.631e-05	4.615	19 ACTN4, ATP6V0A4, ATP6V0D2, ATP6V1C2, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4	112	monovalent inorganic cation transport
GO:0046903	4.599e-05	7.911	25 AGR2, AQP3, ATP6V0A4, BDKRB2, CEL, CLDN16, CTGF, DAB2, EGF, FAM3B, GHRHR, HNF1A, KCNJ1, KCNK5, KCNQ1, LIF, LLGL2, MYO6, NPHS2, NPR3, SCIN, SCNN1A, SCNN1B, SCNN1G, TRPV4	192	secretion
GO:0006812	2.503e-04	9.395	26 ACTN4, ATP6V0A4, ATP6V0D2, ATP6V1C2, BSPRY, CTGF, EGF, F2RL3, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, PLCG2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TRPV4	228	cation transport
GO:0006814	1.743e-03	1.937	10 SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4	47	sodium ion transport
GO:0048771	2.099e-03	1.236	8 ELF3, ERBB2, HNF1A, ITGB3, LIF, NOX4, SLC34A1, SPP1	30	tissue remodeling
GO:0009653	2.159e-03	20.64	40 ADM, AQP3, ARHGAP24, BARX2, CASR, COL4A3, CPM, CRYAA, CTGF, CTNND1, CTSH, DAB2, EGF, ELF3, ENPEP, ERBB2, FOXI1, GATA3, GJA5, HNF1A, HOXA10, HOXB7, HOXD10, HOXD4, ITGB3, LIF, LMX1B, MYO6, NOX4, PLAT, PLAU, PROX1, SMO, SPP1, TBX2, TCF21, TFCP2L1, TINAG, VCAM1, WNT8B	501	anatomical structure morphogenesis
GO:0006508	2.749e-03	11	26 ACE2, BACE2, CAPN5, CPM, CTSH, DPEP1, DPP4, ENPEP, FBXL5, FBXO7, FBXW7, MMP7, OVCH2, PAPPA2, PEPD, PLAT, PLAU, PRSS23, PSMD12, SCRN2, ST14, TINAG, TMEM27, TMPRSS2, TMPRSS4, XPNPEP2	267	proteolysis
GO:0070482	2.973e-03	2.513	11 ACTN4, ADM, CRYAA, CTGF, DPP4, HSD11B2, PLAT, PLAU, SCNN1B, SCNN1G, VCAM1	61	response to oxygen levels
GO:0065008	3.963e-03	25.96	46 ACE2, ADM, AGR2, AQP3, ATP6V0A4, BACE2, BDKRB2, CASR, CEL, CLDN16, CRYAA, CTGF, CTSH, CUBN, DAB2, ERBB2, F2RL1, F2RL3, FAM3B, FBXL5, FBXO7, GHRHR, HNF1A, HSD11B2, IGFBP7, ITGB3, KCNQ1, LIF, MAL, MYO6, NOX4, NPR3, PAPPA2, PLAT, PLAU, PLCG2, RHCG, SCIN, SEH1L, SLC34A1, SLC9A3, SLC9A4, SMO, SPP1, TRPV4, WISP1	630	regulation of biological quality
GO:0030001	4.735e-03	8.2	21 BSPRY, CTGF, EGF, F2RL3, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, PLCG2, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TRPV4	199	metal ion transport
GO:0051179	4.807e-03	51.67	76 ACTN4, AGR2, AQP3, ATP6V0A4, ATP6V0D2, ATP6V1C2, BCAP29, BDKRB2, BSPRY, CEL, CLDN16, CRYAA, CTGF, CTSH, CUBN, DAB2, DPP4, EGF, ELMO3, ENPEP, F2RL1, F2RL3, FAM3B, GHRHR, GJA5, HNF1A, ITGB3, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIF13B, LIF, LLGL2, LMX1B, MAL, MYO6, NPHS2, NPR3, PLA2R1, PLAT, PLAU, PLCG2, PROX1, RAB11FIP1, RAB11FIP3, RAB17, RAB7L1, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SEH1L, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SMO, SNX5, SPAST, STAP1, TRPV4, VCAM1	1254	localization
GO:0001666	7.064e-03	2.349	10 ACTN4, ADM, CRYAA, DPP4, HSD11B2, PLAT, PLAU, SCNN1B, SCNN1G, VCAM1	57	response to hypoxia
GO:0051234	8.285e-03	44.62	67 ACTN4, AGR2, AQP3, ATP6V0A4, ATP6V0D2, ATP6V1C2, BCAP29, BDKRB2, BSPRY, CEL, CLDN16, CRYAA, CTGF, CUBN, DAB2, DPP4, EGF, ELMO3, F2RL3, FAM3B, GHRHR, GJA5, HNF1A, ITGB3, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIF13B, LIF, LLGL2, MYO6, NPHS2, NPR3, PLA2R1, PLCG2, RAB11FIP1, RAB11FIP3, RAB17, RAB7L1, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SEH1L, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SMO, SNX5, SPAST, STAP1, TRPV4	1083	establishment of localization
GO:0006810	1.028e-02	44.13	66 ACTN4, AGR2, AQP3, ATP6V0A4, ATP6V0D2, ATP6V1C2, BCAP29, BDKRB2, BSPRY, CEL, CLDN16, CRYAA, CTGF, CUBN, DAB2, EGF, ELMO3, F2RL3, FAM3B, GHRHR, GJA5, HNF1A, ITGB3, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIF13B, LIF, LLGL2, MYO6, NPHS2, NPR3, PLA2R1, PLCG2, RAB11FIP1, RAB11FIP3, RAB17, RAB7L1, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SEH1L, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SMO, SNX5, SPAST, STAP1, TRPV4	1071	transport
GO:0046849	1.157e-02	0.5769	5 HNF1A, ITGB3, NOX4, SLC34A1, SPP1	14	bone remodeling
GO:0006811	1.189e-02	13.68	28 ACTN4, ATP6V0A4, ATP6V0D2, ATP6V1C2, BSPRY, CLDN16, CTGF, EGF, F2RL3, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, PLCG2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC26A7, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TRPV4	332	ion transport
GO:0050878	1.670e-02	3.173	11 AGR2, AQP3, CEL, F2RL1, F2RL3, GHRHR, HSD11B2, ITGB3, NPR3, PLAT, PLAU	77	regulation of body fluid levels
GO:0007565	1.827e-02	1.772	8 ADM, HSD11B2, IGFBP7, LIF, PAPPA, PLAU, SPP1, TFCP2L1	43	female pregnancy
GO:0015849	2.478e-02	2.843	10 BDKRB2, HNF1A, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	organic acid transport
GO:0046942	2.478e-02	2.843	10 BDKRB2, HNF1A, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	carboxylic acid transport
GO:0048878	2.592e-02	8.9	20 ADM, ATP6V0A4, BDKRB2, CASR, CLDN16, ERBB2, F2RL1, F2RL3, FBXL5, GHRHR, HNF1A, KCNQ1, MAL, NPR3, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, TRPV4	216	chemical homeostasis
GO:0044243	2.596e-02	0.412	4 ACE2, CEL, MMP7, PEPD	10	multicellular organismal catabolic process
GO:0050801	2.809e-02	7.005	17 ADM, ATP6V0A4, BDKRB2, CASR, CLDN16, ERBB2, F2RL1, F2RL3, FBXL5, KCNQ1, MAL, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, TRPV4	170	ion homeostasis
GO:0048598	3.041e-02	5.81	15 ADM, CRYAA, FOXI1, GJA5, HNF1A, HOXA10, HOXB7, HOXD10, HOXD4, MYO6, PROX1, TCF21, TINAG, VCAM1, WNT8B	141	embryonic morphogenesis
GO:0048562	4.386e-02	2.101	8 CRYAA, FOXI1, HOXB7, HOXD10, HOXD4, MYO6, PROX1, TCF21	51	embryonic organ morphogenesis
GO:0048568	4.544e-02	3.708	11 ADM, CRYAA, FOXI1, HOXB7, HOXD10, HOXD4, LIF, MYO6, PROX1, TCF21, VCAM1	90	embryonic organ development
GO:0007566	4.620e-02	0.4945	4 IGFBP7, LIF, PLAU, SPP1	12	embryo implantation
GO:0045453	4.620e-02	0.4945	4 HNF1A, ITGB3, NOX4, SPP1	12	bone resorption
GO:0034220	4.934e-02	1.236	6 ACTN4, ATP6V0A4, ATP6V0D2, ATP6V1C2, EGF, PLCG2	30	ion transmembrane transport
GO:0055080	4.942e-02	4.945	13 ADM, ATP6V0A4, BDKRB2, CASR, CLDN16, F2RL1, F2RL3, FBXL5, PLCG2, RHCG, SLC9A3, SLC9A4, TRPV4	120	cation homeostasis

Id	Pvalue	ExpCount	Count	Size	Term
GO:0045177	6.171e-09	2.915	19 ATP6V0A4, ATP6V0D2, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, MAL, PLAT, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC5A12, SLC9A3, SLC9A4, VCAM1	75	apical part of cell
GO:0016324	7.497e-09	2.293	17 ATP6V0A4, ATP6V0D2, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, MAL, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC5A12, SLC9A3, SLC9A4	59	apical plasma membrane
GO:0005886	1.227e-04	44.03	72 ACE2, ANXA13, AQP3, ARHGAP24, ATP6V0A4, ATP6V0D2, BDKRB2, C18orf1, CASR, CDH6, CLDN16, CPM, CTGF, CTNND1, CUBN, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, F2RL1, F2RL3, GHRHR, GJA5, GPR114, GPR56, IL1RL1, ILDR1, ITGB3, ITM2B, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIRREL, KL, MAL, MYO6, NOX4, NPHS2, PLA2R1, PLAU, PLCG2, PLEK2, PROM2, RAB17, RAB7L1, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, TM7SF3, TMPRSS2, TRPV4, VCAM1, XPNPEP2	1133	plasma membrane
GO:0044459	3.072e-04	28.02	51 AQP3, ARHGAP24, ATP6V0A4, ATP6V0D2, BDKRB2, CASR, CLDN16, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, F2RL1, F2RL3, GJA5, GPR56, IL1RL1, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KL, MAL, MYO6, NOX4, NPHS2, PLA2R1, PLEK2, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A3, SLC15A1, SLC16A4, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, TMPRSS2, TRPV4, VCAM1	721	plasma membrane part
GO:0031253	1.028e-03	1.671	9 ATP6V0A4, CUBN, DPEP1, DPP4, MYO6, PLEK2, PROM2, SLC34A1, SLC9A3	43	cell projection membrane
GO:0005903	1.309e-03	0.6995	6 ATP6V0A4, CUBN, ENPEP, SLC13A1, SLC34A1, SLC9A3	18	brush border
GO:0005576	1.711e-03	20.71	39 ACE2, ACPP, ADM, AGR2, C8orf84, CEL, COL4A3, COL4A4, CTGF, CXCL14, DPP4, EGF, FAM150B, FAM3B, FAM55C, IGFBP7, IL1RL1, KL, LAD1, LIF, METRNL, MMP7, NPNT, OLFM4, OVCH2, PAPPA, PAPPA2, PLA2R1, PLAT, PLAU, PRSS23, SOSTDC1, SPP1, ST14, TINAG, TMPRSS2, VCAM1, WISP1, WNT8B	533	extracellular region
GO:0034706	1.797e-03	0.1166	3 SCNN1A, SCNN1B, SCNN1G	3	sodium channel complex
GO:0009986	2.624e-03	4.896	15 ACE2, BACE2, CUBN, DPP4, ENPEP, GHRHR, IL1RL1, ITGB3, PLAT, PLAU, SCNN1A, SCNN1B, SCNN1G, SLC9A3, VCAM1	126	cell surface
GO:0031224	3.661e-03	62.84	87 ACE2, AQP3, ATP6V0A4, BACE2, BCAP29, BDKRB2, C18orf1, CA12, CASR, CDH6, CLDN16, CLPTM1L, CPM, DENND5B, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, F2RL1, F2RL3, GALNT10, GALNT14, GCNT3, GHRHR, GJA5, GPR114, GPR56, IL1RL1, ILDR1, ITGB3, ITM2B, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIRREL, KL, KLHDC7A, MAL, NOX4, NPHS2, NPR3, PAQR5, PAQR9, PLA2R1, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SEH1L, SGK196, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC44A3, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SMO, SPAST, SPTLC3, ST14, SUSD1, SUSD2, TM7SF3, TMEM171, TMEM27, TMEM51, TMPRSS2, TMPRSS4, TRPV4, VCAM1, XPNPEP2, ZDHHC6	1617	intrinsic to membrane
GO:0044421	5.495e-03	12.44	26 ACE2, ADM, C8orf84, CEL, COL4A3, COL4A4, CTGF, CXCL14, EGF, FAM3B, IGFBP7, IL1RL1, KL, LAD1, LIF, MMP7, NPNT, OLFM4, PLA2R1, PLAT, PLAU, SPP1, ST14, TINAG, VCAM1, WNT8B	320	extracellular region part
GO:0016020	7.387e-03	90.43	114 ACE2, ACPP, ANXA13, AQP3, ARHGAP24, ATP6V0A4, ATP6V0D2, ATP6V1C2, BACE2, BCAP29, BDKRB2, BSPRY, C18orf1, CA12, CASR, CDH6, CEL, CLDN16, CLPTM1L, CPM, CTGF, CTNND1, CUBN, DAB2, DENND5B, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, F2RL1, F2RL3, FARP1, GALNT10, GALNT14, GCNT3, GHRHR, GJA5, GPR114, GPR56, IL1RL1, ILDR1, ITGB3, ITM2B, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIRREL, KL, KLHDC7A, MAL, MYO6, NOX4, NPHS2, NPNT, NPR3, PAPPA, PAPPA2, PAQR5, PAQR9, PHLPP1, PLA2R1, PLAU, PLCG2, PLEK2, PROM2, PTPN1, RAB11FIP1, RAB11FIP3, RAB17, RAB7L1, RHCG, RIPK4, SCNN1A, SCNN1B, SCNN1G, SEH1L, SGK196, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC44A3, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SMO, SPAST, SPTLC3, ST14, SUSD1, SUSD2, TFCP2L1, TM7SF3, TMEM171, TMEM27, TMEM51, TMPRSS2, TMPRSS4, TRPV4, VCAM1, XPNPEP2, ZDHHC6	2327	membrane
GO:0044425	7.640e-03	73.8	97 ACE2, AQP3, ARHGAP24, ATP6V0A4, ATP6V0D2, ATP6V1C2, BACE2, BCAP29, BDKRB2, C18orf1, CA12, CASR, CDH6, CEL, CLDN16, CLPTM1L, CPM, CUBN, DAB2, DENND5B, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, F2RL1, F2RL3, FARP1, GALNT10, GALNT14, GCNT3, GHRHR, GJA5, GPR114, GPR56, IL1RL1, ILDR1, ITGB3, ITM2B, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIRREL, KL, KLHDC7A, MAL, MYO6, NOX4, NPHS2, NPR3, PAQR5, PAQR9, PLA2R1, PLEK2, PROM2, PTPN1, RHCG, SCNN1A, SCNN1B, SCNN1G, SEH1L, SGK196, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC44A3, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SMO, SPAST, SPTLC3, ST14, SUSD1, SUSD2, TM7SF3, TMEM171, TMEM27, TMEM51, TMPRSS2, TMPRSS4, TRPV4, VCAM1, XPNPEP2, ZDHHC6	1899	membrane part
GO:0016021	7.850e-03	61.56	84 ACE2, AQP3, ATP6V0A4, BACE2, BCAP29, BDKRB2, C18orf1, CA12, CASR, CDH6, CLDN16, CLPTM1L, DENND5B, DPP4, EGF, ENPEP, EPCAM, ERBB2, F2RL1, F2RL3, GALNT10, GALNT14, GCNT3, GHRHR, GJA5, GPR114, GPR56, IL1RL1, ILDR1, ITGB3, ITM2B, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIRREL, KL, KLHDC7A, MAL, NOX4, NPHS2, NPR3, PAQR5, PAQR9, PLA2R1, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SEH1L, SGK196, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC44A3, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SMO, SPAST, SPTLC3, ST14, SUSD1, SUSD2, TM7SF3, TMEM171, TMEM27, TMEM51, TMPRSS2, TMPRSS4, TRPV4, VCAM1, ZDHHC6	1584	integral to membrane
GO:0009897	1.064e-02	1.904	8 CUBN, ENPEP, IL1RL1, ITGB3, SCNN1A, SCNN1B, SCNN1G, VCAM1	49	external side of plasma membrane
GO:0033176	1.903e-02	0.2332	3 ATP6V0A4, ATP6V0D2, ATP6V1C2	6	proton-transporting V-type ATPase complex
GO:0005615	1.958e-02	8.783	19 ACE2, ADM, CEL, CTGF, CXCL14, EGF, FAM3B, IGFBP7, IL1RL1, KL, LIF, MMP7, OLFM4, PLA2R1, PLAT, PLAU, SPP1, ST14, VCAM1	226	extracellular space
GO:0031526	2.089e-02	0.5052	4 ATP6V0A4, CUBN, SLC34A1, SLC9A3	13	brush border membrane
GO:0016471	2.505e-02	0.07772	2 ATP6V0A4, ATP6V0D2	2	vacuolar proton-transporting V-type ATPase complex
GO:0016323	4.042e-02	3.575	10 AQP3, ARHGAP24, EPCAM, ERBB2, NOX4, PROM2, RHCG, SLC26A7, SLC9A4, ST14	92	basolateral plasma membrane

Id	Pvalue	ExpCount	Count	Size	Term
GO:0070011	5.782e-05	6.882	23 ACE2, BACE2, CAPN5, CPM, CTSH, DPEP1, DPP4, ENPEP, MMP7, OVCH2, PAPPA, PAPPA2, PEPD, PLAT, PLAU, PRSS23, SCRN2, ST14, TINAG, TMEM27, TMPRSS2, TMPRSS4, XPNPEP2	171	peptidase activity, acting on L-amino acid peptides
GO:0008233	1.053e-04	7.164	23 ACE2, BACE2, CAPN5, CPM, CTSH, DPEP1, DPP4, ENPEP, MMP7, OVCH2, PAPPA, PAPPA2, PEPD, PLAT, PLAU, PRSS23, SCRN2, ST14, TINAG, TMEM27, TMPRSS2, TMPRSS4, XPNPEP2	178	peptidase activity
GO:0008238	1.177e-03	1.489	9 ACE2, CPM, DPEP1, DPP4, ENPEP, PEPD, SCRN2, TMEM27, XPNPEP2	37	exopeptidase activity
GO:0022804	1.433e-03	5.232	17 ATP6V0A4, ATP6V1C2, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4	130	active transmembrane transporter activity
GO:0022857	1.889e-03	14.81	32 AQP3, ATP6V0A4, ATP6V0D2, ATP6V1C2, CLDN16, GJA5, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, MAL, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPV4	368	transmembrane transporter activity
GO:0015291	2.251e-03	3.381	13 SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC5A12, SLC5A9, SLC6A19, SLC9A3, SLC9A4	84	secondary active transmembrane transporter activity
GO:0008324	2.682e-03	9.136	23 ATP6V0A4, ATP6V0D2, ATP6V1C2, CLDN16, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC15A1, SLC1A7, SLC2A9, SLC5A9, SLC6A19, SLC9A3, SLC9A4, TRPV4	227	cation transmembrane transporter activity
GO:0022890	3.686e-03	3.099	12 ATP6V0A4, ATP6V0D2, ATP6V1C2, CLDN16, RHCG, SLC13A1, SLC13A3, SLC1A7, SLC5A9, SLC6A19, SLC9A3, SLC9A4	77	inorganic cation transmembrane transporter activity
GO:0015293	4.569e-03	2.254	10 SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC2A9, SLC34A1, SLC5A12, SLC5A9, SLC6A19	56	symporter activity
GO:0004252	4.889e-03	1.449	8 DPP4, OVCH2, PLAT, PLAU, PRSS23, ST14, TMPRSS2, TMPRSS4	36	serine-type endopeptidase activity
GO:0015077	5.164e-03	2.294	10 ATP6V0A4, ATP6V0D2, ATP6V1C2, SLC13A1, SLC13A3, SLC1A7, SLC5A9, SLC6A19, SLC9A3, SLC9A4	57	monovalent inorganic cation transmembrane transporter activity
GO:0004175	5.193e-03	4.266	14 BACE2, CAPN5, CTSH, DPP4, MMP7, OVCH2, PAPPA, PLAT, PLAU, PRSS23, ST14, TINAG, TMPRSS2, TMPRSS4	106	endopeptidase activity
GO:0022891	5.583e-03	13.76	29 AQP3, ATP6V0A4, ATP6V0D2, ATP6V1C2, CLDN16, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPV4	342	substrate-specific transmembrane transporter activity
GO:0008237	1.009e-02	2.535	10 ACE2, CPM, DPEP1, ENPEP, MMP7, PAPPA, PAPPA2, PEPD, TMEM27, XPNPEP2	63	metallopeptidase activity
GO:0008236	1.187e-02	1.69	8 DPP4, OVCH2, PLAT, PLAU, PRSS23, ST14, TMPRSS2, TMPRSS4	42	serine-type peptidase activity
GO:0017171	1.187e-02	1.69	8 DPP4, OVCH2, PLAT, PLAU, PRSS23, ST14, TMPRSS2, TMPRSS4	42	serine hydrolase activity
GO:0015280	1.322e-02	0.161	3 SCNN1A, SCNN1B, SCNN1G	4	amiloride-sensitive sodium channel activity
GO:0016805	1.322e-02	0.161	3 DPEP1, PEPD, SCRN2	4	dipeptidase activity
GO:0005044	1.542e-02	0.6439	5 C8orf84, SUSD2, TINAG, TMPRSS2, TMPRSS4	16	scavenger receptor activity
GO:0015075	1.679e-02	12.07	25 ATP6V0A4, ATP6V0D2, ATP6V1C2, CLDN16, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC15A1, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC5A9, SLC6A19, SLC9A3, SLC9A4, TRPV4	300	ion transmembrane transporter activity
GO:0015294	2.125e-02	1.449	7 SLC13A1, SLC13A3, SLC15A1, SLC1A7, SLC2A9, SLC5A9, SLC6A19	36	solute:cation symporter activity
GO:0005215	2.164e-02	18.27	33 AQP3, ATP6V0A4, ATP6V0D2, ATP6V1C2, CLDN16, CUBN, GJA5, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, MAL, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPV4	454	transporter activity
GO:0008235	2.416e-02	0.7244	5 CPM, DPEP1, ENPEP, PEPD, XPNPEP2	18	metalloexopeptidase activity
GO:0022892	2.885e-02	15.62	29 AQP3, ATP6V0A4, ATP6V0D2, ATP6V1C2, CLDN16, KCNE3, KCNJ1, KCNJ16, KCNK5, KCNQ1, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC1A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPV4	388	substrate-specific transporter activity
GO:0005342	3.132e-02	1.57	7 SLC13A3, SLC16A4, SLC1A7, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	organic acid transmembrane transporter activity
GO:0046943	3.132e-02	1.57	7 SLC13A3, SLC16A4, SLC1A7, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	carboxylic acid transmembrane transporter activity
GO:0050699	4.125e-02	0.2415	3 SCNN1A, SCNN1B, SCNN1G	6	WW domain binding
GO:0015078	4.910e-02	0.8854	5 ATP6V0A4, ATP6V0D2, ATP6V1C2, SLC9A3, SLC9A4	22	hydrogen ion transmembrane transporter activity

Id	Pvalue	ExpCount	Count	Size	Term
05110	1.179e-02	0.6062	5 ATP6V0A4, ATP6V0D2, ATP6V1C2, KCNQ1, PLCG2	15	Vibrio cholerae infection
04960	1.534e-02	0.6466	5 HSD11B2, KCNJ1, SCNN1A, SCNN1B, SCNN1G	16	Aldosterone-regulated sodium reabsorption

No enriched terms

No enriched terms

Entrez genes

ACE2angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ENSG00000130234), score: 0.58 ACMSDaminocarboxymuconate semialdehyde decarboxylase (ENSG00000153086), score: 0.6 ACOT11acyl-CoA thioesterase 11 (ENSG00000162390), score: 0.63 ACPPacid phosphatase, prostate (ENSG00000014257), score: 0.89 ACTN4actinin, alpha 4 (ENSG00000130402), score: 0.5 ADMadrenomedullin (ENSG00000148926), score: 0.6 AGR2anterior gradient homolog 2 (Xenopus laevis) (ENSG00000106541), score: 0.54 AIM1absent in melanoma 1 (ENSG00000112297), score: 0.55 ALPK1alpha-kinase 1 (ENSG00000073331), score: 0.51 ANXA13annexin A13 (ENSG00000104537), score: 0.63 AQP3aquaporin 3 (Gill blood group) (ENSG00000165272), score: 0.51 ARHGAP24Rho GTPase activating protein 24 (ENSG00000138639), score: 0.54 ARMC7armadillo repeat containing 7 (ENSG00000125449), score: 0.62 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.71 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.68 ATP6V1C2ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 (ENSG00000143882), score: 0.51 BACE2beta-site APP-cleaving enzyme 2 (ENSG00000182240), score: 0.54 BARX2BARX homeobox 2 (ENSG00000043039), score: 0.8 BBOX1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (ENSG00000129151), score: 0.63 BCAP29B-cell receptor-associated protein 29 (ENSG00000075790), score: -0.47 BDKRB2bradykinin receptor B2 (ENSG00000168398), score: 0.67 BNC2basonuclin 2 (ENSG00000173068), score: 0.53 BSPRYB-box and SPRY domain containing (ENSG00000119411), score: 0.51 C18orf1chromosome 18 open reading frame 1 (ENSG00000168675), score: -0.52 C8orf84chromosome 8 open reading frame 84 (ENSG00000164764), score: 0.63 C9orf72chromosome 9 open reading frame 72 (ENSG00000147894), score: -0.52 CA12carbonic anhydrase XII (ENSG00000074410), score: 0.8 CAPN5calpain 5 (ENSG00000149260), score: 0.51 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.63 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (ENSG00000113361), score: 0.63 CELcarboxyl ester lipase (bile salt-stimulated lipase) (ENSG00000170835), score: 0.53 CHCHD8coiled-coil-helix-coiled-coil-helix domain containing 8 (ENSG00000181924), score: 0.52 CLDN16claudin 16 (ENSG00000113946), score: 0.67 CLPTM1LCLPTM1-like (ENSG00000049656), score: 0.55 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.65 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.54 CPEB3cytoplasmic polyadenylation element binding protein 3 (ENSG00000107864), score: -0.47 CPMcarboxypeptidase M (ENSG00000135678), score: 0.56 CRYAAcrystallin, alpha A (ENSG00000160202), score: 0.98 CRYL1crystallin, lambda 1 (ENSG00000165475), score: 0.61 CTGFconnective tissue growth factor (ENSG00000118523), score: 0.53 CTNND1catenin (cadherin-associated protein), delta 1 (ENSG00000198561), score: 0.53 CTSHcathepsin H (ENSG00000103811), score: 0.59 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.66 CXCL14chemokine (C-X-C motif) ligand 14 (ENSG00000145824), score: 0.6 DAAM1dishevelled associated activator of morphogenesis 1 (ENSG00000100592), score: -0.53 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.6 DDCdopa decarboxylase (aromatic L-amino acid decarboxylase) (ENSG00000132437), score: 0.71 DENND2DDENN/MADD domain containing 2D (ENSG00000162777), score: 0.52 DENND5BDENN/MADD domain containing 5B (ENSG00000170456), score: -0.49 DPEP1dipeptidase 1 (renal) (ENSG00000015413), score: 0.72 DPP4dipeptidyl-peptidase 4 (ENSG00000197635), score: 0.57 EBNA1BP2EBNA1 binding protein 2 (ENSG00000117395), score: 0.58 EGFepidermal growth factor (ENSG00000138798), score: 0.61 EHFets homologous factor (ENSG00000135373), score: 0.58 ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ENSG00000163435), score: 0.66 ELF5E74-like factor 5 (ets domain transcription factor) (ENSG00000135374), score: 0.8 ELMO3engulfment and cell motility 3 (ENSG00000102890), score: 0.51 ENPEPglutamyl aminopeptidase (aminopeptidase A) (ENSG00000138792), score: 0.59 EPCAMepithelial cell adhesion molecule (ENSG00000119888), score: 0.65 ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ENSG00000141736), score: 0.57 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.64 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.76 F2RL3coagulation factor II (thrombin) receptor-like 3 (ENSG00000127533), score: 0.5 FAM150Bfamily with sequence similarity 150, member B (ENSG00000189292), score: 0.72 FAM3Bfamily with sequence similarity 3, member B (ENSG00000183844), score: 0.7 FAM55Cfamily with sequence similarity 55, member C (ENSG00000144815), score: -0.48 FAM83Hfamily with sequence similarity 83, member H (ENSG00000180921), score: 0.54 FARP1FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) (ENSG00000152767), score: 0.58 FBXL5F-box and leucine-rich repeat protein 5 (ENSG00000118564), score: 0.6 FBXO7F-box protein 7 (ENSG00000100225), score: 0.55 FBXW7F-box and WD repeat domain containing 7 (ENSG00000109670), score: -0.47 FOXI1forkhead box I1 (ENSG00000168269), score: 0.81 GALNT10UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) (ENSG00000164574), score: 0.54 GALNT14UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (ENSG00000158089), score: 0.52 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.72 GCNT3glucosaminyl (N-acetyl) transferase 3, mucin type (ENSG00000140297), score: 0.57 GHRHRgrowth hormone releasing hormone receptor (ENSG00000106128), score: 0.61 GJA5gap junction protein, alpha 5, 40kDa (ENSG00000143140), score: 0.51 GLB1galactosidase, beta 1 (ENSG00000170266), score: 0.51 GPR114G protein-coupled receptor 114 (ENSG00000159618), score: 0.55 GPR56G protein-coupled receptor 56 (ENSG00000205336), score: 0.57 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.69 HNF1AHNF1 homeobox A (ENSG00000135100), score: 0.54 HOXA10homeobox A10 (ENSG00000153807), score: 0.77 HOXB7homeobox B7 (ENSG00000120087), score: 0.68 HOXD10homeobox D10 (ENSG00000128710), score: 0.69 HOXD4homeobox D4 (ENSG00000170166), score: 0.72 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.74 IGFBP7insulin-like growth factor binding protein 7 (ENSG00000163453), score: 0.53 IL1RL1interleukin 1 receptor-like 1 (ENSG00000115602), score: 0.77 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.69 IMPA2inositol(myo)-1(or 4)-monophosphatase 2 (ENSG00000141401), score: 0.73 ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ENSG00000056345), score: 0.72 ITM2Bintegral membrane protein 2B (ENSG00000136156), score: 0.52 KCNE3potassium voltage-gated channel, Isk-related family, member 3 (ENSG00000175538), score: 0.59 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.81 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.54 KCNK5potassium channel, subfamily K, member 5 (ENSG00000164626), score: 0.62 KCNQ1potassium voltage-gated channel, KQT-like subfamily, member 1 (ENSG00000053918), score: 0.54 KIF12kinesin family member 12 (ENSG00000136883), score: 0.64 KIF13Bkinesin family member 13B (ENSG00000197892), score: 0.57 KIRRELkin of IRRE like (Drosophila) (ENSG00000183853), score: 0.54 KLklotho (ENSG00000133116), score: 0.64 KLHDC7Akelch domain containing 7A (ENSG00000179023), score: 0.66 KLHL28kelch-like 28 (Drosophila) (ENSG00000179454), score: -0.48 LAD1ladinin 1 (ENSG00000159166), score: 0.55 LGALS2lectin, galactoside-binding, soluble, 2 (ENSG00000100079), score: 0.74 LIFleukemia inhibitory factor (cholinergic differentiation factor) (ENSG00000128342), score: 0.53 LLGL2lethal giant larvae homolog 2 (Drosophila) (ENSG00000073350), score: 0.59 LMX1BLIM homeobox transcription factor 1, beta (ENSG00000136944), score: 0.81 LPIN3lipin 3 (ENSG00000132793), score: 0.58 MALmal, T-cell differentiation protein (ENSG00000172005), score: 0.56 METRNLmeteorin, glial cell differentiation regulator-like (ENSG00000176845), score: 0.52 METTL9methyltransferase like 9 (ENSG00000197006), score: 0.6 MMP7matrix metallopeptidase 7 (matrilysin, uterine) (ENSG00000137673), score: 1 MYO6myosin VI (ENSG00000196586), score: 0.55 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.74 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 0.9 NPNTnephronectin (ENSG00000168743), score: 0.64 NPR3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (ENSG00000113389), score: 0.61 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.54 OLFM4olfactomedin 4 (ENSG00000102837), score: 0.77 ORC6Lorigin recognition complex, subunit 6 like (yeast) (ENSG00000091651), score: -0.47 OVCH2ovochymase 2 (gene/pseudogene) (ENSG00000183378), score: 0.85 PABPC1Lpoly(A) binding protein, cytoplasmic 1-like (ENSG00000101104), score: 0.54 PAPPApregnancy-associated plasma protein A, pappalysin 1 (ENSG00000182752), score: 0.63 PAPPA2pappalysin 2 (ENSG00000116183), score: 0.77 PAQR5progestin and adipoQ receptor family member V (ENSG00000137819), score: 0.53 PAQR9progestin and adipoQ receptor family member IX (ENSG00000188582), score: -0.51 PEPDpeptidase D (ENSG00000124299), score: 0.69 PHLPP1PH domain and leucine rich repeat protein phosphatase 1 (ENSG00000081913), score: -0.49 PLA2R1phospholipase A2 receptor 1, 180kDa (ENSG00000153246), score: 0.75 PLATplasminogen activator, tissue (ENSG00000104368), score: 0.57 PLAUplasminogen activator, urokinase (ENSG00000122861), score: 0.55 PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific) (ENSG00000197943), score: 0.77 PLEK2pleckstrin 2 (ENSG00000100558), score: 0.66 PLEKHJ1pleckstrin homology domain containing, family J member 1 (ENSG00000104886), score: 0.57 PNPLA1patatin-like phospholipase domain containing 1 (ENSG00000180316), score: 0.64 PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit (ENSG00000111725), score: 0.7 PROM2prominin 2 (ENSG00000155066), score: 0.77 PROX1prospero homeobox 1 (ENSG00000117707), score: -0.54 PRSS23protease, serine, 23 (ENSG00000150687), score: 0.51 PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (ENSG00000197170), score: -0.5 PTPN1protein tyrosine phosphatase, non-receptor type 1 (ENSG00000196396), score: 0.57 QARSglutaminyl-tRNA synthetase (ENSG00000172053), score: 0.51 RAB11FIP1RAB11 family interacting protein 1 (class I) (ENSG00000156675), score: 0.52 RAB11FIP3RAB11 family interacting protein 3 (class II) (ENSG00000090565), score: 0.55 RAB17RAB17, member RAS oncogene family (ENSG00000124839), score: 0.64 RAB7L1RAB7, member RAS oncogene family-like 1 (ENSG00000117280), score: 0.6 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.77 RIPK4receptor-interacting serine-threonine kinase 4 (ENSG00000183421), score: 0.55 RNF152ring finger protein 152 (ENSG00000176641), score: 0.7 SAP30Sin3A-associated protein, 30kDa (ENSG00000164105), score: -0.5 SCINscinderin (ENSG00000006747), score: 0.66 SCNN1Asodium channel, nonvoltage-gated 1 alpha (ENSG00000111319), score: 0.73 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.69 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.69 SCRN2secernin 2 (ENSG00000141295), score: 0.55 SEH1LSEH1-like (S. cerevisiae) (ENSG00000085415), score: -0.49 SGK196protein kinase-like protein SgK196 (ENSG00000185900), score: -0.54 SGK2serum/glucocorticoid regulated kinase 2 (ENSG00000101049), score: 0.51 SH3YL1SH3 domain containing, Ysc84-like 1 (S. cerevisiae) (ENSG00000035115), score: 0.64 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.53 SIM2single-minded homolog 2 (Drosophila) (ENSG00000159263), score: 0.74 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.67 SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (ENSG00000158296), score: 0.63 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (ENSG00000088386), score: 0.59 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.65 SLC1A7solute carrier family 1 (glutamate transporter), member 7 (ENSG00000162383), score: 0.53 SLC26A7solute carrier family 26, member 7 (ENSG00000147606), score: 0.78 SLC2A9solute carrier family 2 (facilitated glucose transporter), member 9 (ENSG00000109667), score: 0.51 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.67 SLC3A1solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 (ENSG00000138079), score: 0.62 SLC44A3solute carrier family 44, member 3 (ENSG00000143036), score: 0.65 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.75 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 0.55 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.68 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.67 SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 3 (ENSG00000066230), score: 0.63 SLC9A4solute carrier family 9 (sodium/hydrogen exchanger), member 4 (ENSG00000180251), score: 0.74 SMOsmoothened homolog (Drosophila) (ENSG00000128602), score: 0.51 SNX5sorting nexin 5 (ENSG00000089006), score: 0.63 SOSTDC1sclerostin domain containing 1 (ENSG00000171243), score: 0.55 SPASTspastin (ENSG00000021574), score: -0.47 SPP1secreted phosphoprotein 1 (ENSG00000118785), score: 0.6 SPTLC3serine palmitoyltransferase, long chain base subunit 3 (ENSG00000172296), score: 0.65 ST14suppression of tumorigenicity 14 (colon carcinoma) (ENSG00000149418), score: 0.6 STAP1signal transducing adaptor family member 1 (ENSG00000035720), score: 0.52 STK32Bserine/threonine kinase 32B (ENSG00000152953), score: 0.75 SUMF1sulfatase modifying factor 1 (ENSG00000144455), score: 0.58 SUSD1sushi domain containing 1 (ENSG00000106868), score: 0.58 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.59 TBC1D1TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 (ENSG00000065882), score: 0.65 TBC1D13TBC1 domain family, member 13 (ENSG00000107021), score: 0.53 TBX2T-box 2 (ENSG00000121068), score: 0.68 TCF21transcription factor 21 (ENSG00000118526), score: 0.54 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.79 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.71 TM7SF3transmembrane 7 superfamily member 3 (ENSG00000064115), score: 0.61 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.54 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.6 TMEM51transmembrane protein 51 (ENSG00000171729), score: 0.57 TMPRSS2transmembrane protease, serine 2 (ENSG00000184012), score: 0.69 TMPRSS4transmembrane protease, serine 4 (ENSG00000137648), score: 0.84 TNRC6Ctrinucleotide repeat containing 6C (ENSG00000078687), score: -0.56 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.71 VCAM1vascular cell adhesion molecule 1 (ENSG00000162692), score: 0.7 WDR72WD repeat domain 72 (ENSG00000166415), score: 0.78 WISP1WNT1 inducible signaling pathway protein 1 (ENSG00000104415), score: 0.53 WNT8Bwingless-type MMTV integration site family, member 8B (ENSG00000075290), score: 0.6 XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (ENSG00000122121), score: 0.67 ZDHHC6zinc finger, DHHC-type containing 6 (ENSG00000023041), score: 0.51 ZNF618zinc finger protein 618 (ENSG00000157657), score: 0.53

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
ptr_kd_f_ca1	ptr	kd	f	_
ppa_kd_m_ca1	ppa	kd	m	_
ggo_kd_m_ca1	ggo	kd	m	_
ggo_kd_f_ca1	ggo	kd	f	_
ptr_kd_m_ca1	ptr	kd	m	_
ppa_kd_f_ca1	ppa	kd	f	_
hsa_kd_f_ca1	hsa	kd	f	_
hsa_kd_m1_ca1	hsa	kd	m	1
hsa_kd_m2_ca1	hsa	kd	m	2