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system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

organic acid transport

The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of, within or between cells by means of some external agent such as a transporter or pore.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

carboxylic acid transport

The directed movement of carboxylic acids into, out of, within or between cells by means of some external agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

all

NA

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

sodium channel complex

An ion channel complex through which sodium ions pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

serine-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.

serine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

scavenger receptor activity

Combining with acetylated low-density lipoproteins, advanced glycation end products, or other polyanionic ligands to initiate a change in cell activity.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

anion transmembrane transporter activity

Catalysis of the transfer of a negatively charged ion from one side of a membrane to the other.

peptidase activity, acting on L-amino acid peptides

Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

symporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

serine hydrolase activity

Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

serine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

serine-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

Id	Pvalue	ExpCount	Count	Size	Term
GO:0007588	9.598e-07	1.087	11 AQP3, ATP6V0A4, CLCN5, CLDN16, DAB2, KCNJ1, KCNK5, NPHS2, SCNN1A, SCNN1B, SCNN1G	24	excretion
GO:0006811	9.524e-05	15.03	36 ABCC4, ANO10, ATP6V0A4, ATP6V0D2, BDKRB1, CLCN5, CLDN16, CLIC6, CTGF, EGF, GABRP, KCNE3, KCNJ1, KCNJ16, KCNK5, PKD2, PLCG2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC22A7, SLC26A7, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TCN2, TRPM6, TRPV4	332	ion transport
GO:0006814	1.378e-04	2.128	12 SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4	47	sodium ion transport
GO:0006812	1.623e-04	10.32	28 ATP6V0A4, ATP6V0D2, BDKRB1, CTGF, EGF, KCNE3, KCNJ1, KCNJ16, KCNK5, PKD2, PLCG2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TCN2, TRPM6, TRPV4	228	cation transport
GO:0015672	3.243e-04	5.071	18 ATP6V0A4, ATP6V0D2, KCNE3, KCNJ1, KCNJ16, KCNK5, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4	112	monovalent inorganic cation transport
GO:0030001	3.637e-04	9.011	25 BDKRB1, CTGF, EGF, KCNE3, KCNJ1, KCNJ16, KCNK5, PKD2, PLCG2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TCN2, TRPM6, TRPV4	199	metal ion transport
GO:0015849	4.390e-03	3.124	12 BDKRB2, HNF1A, SLC10A2, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC25A10, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	organic acid transport
GO:0046942	4.390e-03	3.124	12 BDKRB2, HNF1A, SLC10A2, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC25A10, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	carboxylic acid transport
GO:0055085	1.668e-02	12.59	26 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CYLD, EGF, PKD2, PLCG2, RHCG, SFXN2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A7, SLC25A10, SLC25A42, SLC26A7, SLC5A12, SLC5A9, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	278	transmembrane transport
GO:0046903	2.072e-02	8.694	20 AQP3, ATP6V0A4, BDKRB2, CLCN5, CLDN16, CTGF, DAB2, EGF, FAM3B, FAM3D, HNF1A, KCNJ1, KCNK5, LLGL2, NPHS2, SCIN, SCNN1A, SCNN1B, SCNN1G, TRPV4	192	secretion
GO:0055080	4.166e-02	5.434	14 ATP6V0A4, BDKRB1, BDKRB2, CASR, CLDN16, F2RL1, PKD2, PLCG2, RHCG, SLC9A3, SLC9A4, STC1, TRPV4, UPK3A	120	cation homeostasis

Id	Pvalue	ExpCount	Count	Size	Term
GO:0045177	3.176e-12	3.433	24 AKR1A1, ATP6V0A4, ATP6V0D2, CLCN5, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, LGMN, MAL, PLAT, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC5A12, SLC9A3, SLC9A4, TRPM6, UPK3A	75	apical part of cell
GO:0016324	1.249e-11	2.701	21 AKR1A1, ATP6V0A4, ATP6V0D2, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, MAL, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC5A12, SLC9A3, SLC9A4, TRPM6, UPK3A	59	apical plasma membrane
GO:0044459	2.487e-04	33.01	58 AKR1A1, AQP3, ATP6V0A4, ATP6V0D2, BDKRB1, BDKRB2, CASR, CASS4, CD151, CLCN5, CLDN16, CLDN19, CUBN, CYLD, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, F2RL1, FGFR4, GABRP, GOPC, GPR56, KCNJ1, KCNJ16, KCNK5, KL, MAL, MPP1, MYH9, NCSTN, NOX4, NPHS2, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A7, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, TMPRSS2, TRPM6, TRPV4, UPK3A	721	plasma membrane part
GO:0005903	3.336e-04	0.824	7 ATP6V0A4, CUBN, ENPEP, SLC13A1, SLC34A1, SLC9A3, TRPM6	18	brush border
GO:0005886	3.810e-04	51.87	80 ABCC4, ACE2, AKR1A1, ANKS4B, AQP3, ATP6V0A4, ATP6V0D2, BDKRB1, BDKRB2, CASR, CASS4, CD151, CDH6, CLCN5, CLDN16, CLDN19, CLIC6, CTGF, CUBN, CYLD, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, F2RL1, FGFR4, FRAS1, FRMD6, GABRP, GOPC, GPR114, GPR56, ILDR1, ITM2B, KCNJ1, KCNJ16, KCNK5, KL, MAL, MPP1, MYH9, NCSTN, NOX4, NPHS2, PKD2, PLCG2, PROM2, RAB17, RAB19, RHCG, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC16A12, SLC16A4, SLC19A1, SLC22A7, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, TM7SF3, TMPRSS2, TRPM6, TRPV4, UPK3A, XPNPEP2	1133	plasma membrane
GO:0034706	2.683e-03	0.1373	3 SCNN1A, SCNN1B, SCNN1G	3	sodium channel complex
GO:0031526	4.603e-03	0.5951	5 ATP6V0A4, CUBN, SLC34A1, SLC9A3, TRPM6	13	brush border membrane
GO:0031253	1.232e-02	1.968	8 ATP6V0A4, CUBN, DPEP1, DPP4, PROM2, SLC34A1, SLC9A3, TRPM6	43	cell projection membrane
GO:0016323	1.652e-02	4.212	12 AQP3, CASS4, CLDN19, EPCAM, ERBB2, NOX4, PROM2, RHCG, SLC22A7, SLC26A7, SLC9A4, ST14	92	basolateral plasma membrane
GO:0031224	2.795e-02	74.02	95 ABCC4, ACE2, ACP2, ANO10, AQP3, ATP6V0A4, BDKRB1, BDKRB2, C2orf18, CA12, CASR, CD151, CDH6, CLCN5, CLDN16, CLDN19, CLIC6, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, EVC, F2RL1, FGFR4, FRAS1, GABRP, GALNT14, GPR114, GPR56, ILDR1, ITM2B, KCNE3, KCNJ1, KCNJ16, KCNK5, KL, KLHDC7A, MAL, MARVELD3, MPP1, MYH9, NCSTN, NOX4, NPHS2, PAQR5, PKD2, PQLC3, PROM2, PTPRQ, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC16A12, SLC16A4, SLC19A1, SLC22A7, SLC25A10, SLC25A42, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, SUSD2, SUSD3, TM7SF3, TMCO4, TMEM120B, TMEM138, TMEM171, TMEM27, TMEM51, TMIGD1, TMPRSS13, TMPRSS2, TMPRSS4, TRPM6, TRPV4, UPK3A, XPNPEP2, ZDHHC20, ZPLD1	1617	intrinsic to membrane
GO:0016021	3.214e-02	72.51	93 ABCC4, ACE2, ACP2, ANO10, AQP3, ATP6V0A4, BDKRB1, BDKRB2, C2orf18, CA12, CASR, CD151, CDH6, CLCN5, CLDN16, CLDN19, CLIC6, DPP4, EGF, ENPEP, EPCAM, ERBB2, EVC, F2RL1, FGFR4, FRAS1, GABRP, GALNT14, GPR114, GPR56, ILDR1, ITM2B, KCNE3, KCNJ1, KCNJ16, KCNK5, KL, KLHDC7A, MAL, MARVELD3, MPP1, MYH9, NCSTN, NOX4, NPHS2, PAQR5, PKD2, PQLC3, PROM2, PTPRQ, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC16A12, SLC16A4, SLC19A1, SLC22A7, SLC25A10, SLC25A42, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, SUSD2, SUSD3, TM7SF3, TMCO4, TMEM120B, TMEM138, TMEM171, TMEM27, TMEM51, TMIGD1, TMPRSS13, TMPRSS2, TMPRSS4, TRPM6, TRPV4, UPK3A, ZDHHC20, ZPLD1	1584	integral to membrane
GO:0016471	3.249e-02	0.09156	2 ATP6V0A4, ATP6V0D2	2	vacuolar proton-transporting V-type ATPase complex
GO:0005773	4.199e-02	4.212	11 ACP2, ACPP, ASAH1, ATP6V0A4, ATP6V0D2, C2orf18, CTSH, CUBN, LGMN, NCSTN, SLC3A1	92	vacuole
GO:0005624	4.450e-02	12.54	23 ABCC4, ACP2, ANKRA2, BDKRB1, CD151, CUBN, DPP4, GOPC, HSD11B2, KL, MAL, MPP1, NCSTN, PLCG2, SCNN1A, SCNN1B, SCNN1G, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A7, SLC3A1	274	membrane fraction

Id	Pvalue	ExpCount	Count	Size	Term
GO:0022857	2.416e-05	16.53	40 ABCC4, ANO10, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, GABRP, KCNE3, KCNJ1, KCNJ16, KCNK5, MAL, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC16A12, SLC16A4, SLC19A1, SLC22A7, SLC25A10, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	368	transmembrane transporter activity
GO:0015291	1.365e-04	3.772	16 CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC16A12, SLC16A4, SLC19A1, SLC22A7, SLC26A7, SLC34A1, SLC5A12, SLC5A9, SLC6A19, SLC9A3, SLC9A4	84	secondary active transmembrane transporter activity
GO:0022891	1.594e-04	15.36	36 ABCC4, ANO10, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, GABRP, KCNE3, KCNJ1, KCNJ16, KCNK5, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC22A7, SLC25A10, SLC26A7, SLC34A1, SLC3A1, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	342	substrate-specific transmembrane transporter activity
GO:0022804	1.799e-04	5.838	20 ABCC4, ATP6V0A4, CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC16A12, SLC16A4, SLC19A1, SLC22A7, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4	130	active transmembrane transporter activity
GO:0005215	8.504e-04	20.39	41 ABCC4, ANO10, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, CUBN, GABRP, KCNE3, KCNJ1, KCNJ16, KCNK5, MAL, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC16A12, SLC16A4, SLC19A1, SLC22A7, SLC25A10, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	454	transporter activity
GO:0015075	9.110e-04	13.47	31 ABCC4, ANO10, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, GABRP, KCNE3, KCNJ1, KCNJ16, KCNK5, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC22A7, SLC26A7, SLC34A1, SLC5A9, SLC6A19, SLC9A3, SLC9A4, TRPM6, TRPV4	300	ion transmembrane transporter activity
GO:0022892	1.590e-03	17.42	36 ABCC4, ANO10, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, GABRP, KCNE3, KCNJ1, KCNJ16, KCNK5, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC16A4, SLC22A7, SLC25A10, SLC26A7, SLC34A1, SLC3A1, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	388	substrate-specific transporter activity
GO:0008233	3.062e-03	7.993	21 ACE2, APEH, CTSH, CYLD, DPEP1, DPP4, ENPEP, LGMN, NCSTN, PAPPA, PAPPA2, PEPD, PLAT, ST14, TINAG, TMEM27, TMPRSS13, TMPRSS2, TMPRSS4, TPP2, XPNPEP2	178	peptidase activity
GO:0005044	3.352e-03	0.7185	6 C8orf84, SUSD2, TINAG, TMPRSS13, TMPRSS2, TMPRSS4	16	scavenger receptor activity
GO:0070011	4.741e-03	7.679	20 ACE2, APEH, CTSH, CYLD, DPEP1, DPP4, ENPEP, LGMN, PAPPA, PAPPA2, PEPD, PLAT, ST14, TINAG, TMEM27, TMPRSS13, TMPRSS2, TMPRSS4, TPP2, XPNPEP2	171	peptidase activity, acting on L-amino acid peptides
GO:0008509	7.684e-03	2.919	11 ABCC4, ANO10, CLCN5, CLIC6, GABRP, PKD2, SLC13A1, SLC13A3, SLC22A7, SLC26A7, SLC34A1	65	anion transmembrane transporter activity
GO:0004252	8.896e-03	1.617	8 APEH, DPP4, PLAT, ST14, TMPRSS13, TMPRSS2, TMPRSS4, TPP2	36	serine-type endopeptidase activity
GO:0015293	9.300e-03	2.515	10 SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC16A12, SLC16A4, SLC34A1, SLC5A12, SLC5A9, SLC6A19	56	symporter activity
GO:0008324	1.005e-02	10.19	23 ATP6V0A4, ATP6V0D2, CLDN16, KCNE3, KCNJ1, KCNJ16, KCNK5, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A1, SLC5A9, SLC6A19, SLC9A3, SLC9A4, TRPM6, TRPV4	227	cation transmembrane transporter activity
GO:0008238	1.035e-02	1.662	8 ACE2, DPEP1, DPP4, ENPEP, PEPD, TMEM27, TPP2, XPNPEP2	37	exopeptidase activity
GO:0005342	1.398e-02	1.751	8 SLC10A2, SLC13A3, SLC16A4, SLC25A10, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	organic acid transmembrane transporter activity
GO:0046943	1.398e-02	1.751	8 SLC10A2, SLC13A3, SLC16A4, SLC25A10, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	carboxylic acid transmembrane transporter activity
GO:0015280	1.685e-02	0.1796	3 SCNN1A, SCNN1B, SCNN1G	4	amiloride-sensitive sodium channel activity
GO:0004177	1.738e-02	0.6736	5 DPP4, ENPEP, PEPD, TPP2, XPNPEP2	15	aminopeptidase activity
GO:0008236	2.067e-02	1.886	8 APEH, DPP4, PLAT, ST14, TMPRSS13, TMPRSS2, TMPRSS4, TPP2	42	serine-type peptidase activity
GO:0017171	2.067e-02	1.886	8 APEH, DPP4, PLAT, ST14, TMPRSS13, TMPRSS2, TMPRSS4, TPP2	42	serine hydrolase activity
GO:0022890	2.434e-02	3.458	11 ATP6V0A4, ATP6V0D2, CLDN16, RHCG, SLC10A2, SLC13A1, SLC13A3, SLC5A9, SLC6A19, SLC9A3, SLC9A4	77	inorganic cation transmembrane transporter activity
GO:0015077	3.337e-02	2.56	9 ATP6V0A4, ATP6V0D2, SLC10A2, SLC13A1, SLC13A3, SLC5A9, SLC6A19, SLC9A3, SLC9A4	57	monovalent inorganic cation transmembrane transporter activity
GO:0005272	3.734e-02	0.494	4 PKD2, SCNN1A, SCNN1B, SCNN1G	11	sodium channel activity
GO:0005254	4.378e-02	1.706	7 ABCC4, ANO10, CLCN5, CLIC6, GABRP, PKD2, SLC26A7	38	chloride channel activity
GO:0005253	4.900e-02	1.751	7 ABCC4, ANO10, CLCN5, CLIC6, GABRP, PKD2, SLC26A7	39	anion channel activity

Id	Pvalue	ExpCount	Count	Size	Term
04960	2.263e-03	0.6755	6 HSD11B2, KCNJ1, SCNN1A, SCNN1B, SCNN1G, SGK1	16	Aldosterone-regulated sodium reabsorption
04742	2.303e-02	0.4222	4 PRKACB, SCNN1A, SCNN1B, SCNN1G	10	Taste transduction

No enriched terms

No enriched terms

Entrez genes

ABCC4ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ENSG00000125257), score: 0.53 ACE2angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ENSG00000130234), score: 0.59 ACMSDaminocarboxymuconate semialdehyde decarboxylase (ENSG00000153086), score: 0.6 ACO1aconitase 1, soluble (ENSG00000122729), score: 0.63 ACOT11acyl-CoA thioesterase 11 (ENSG00000162390), score: 0.54 ACP2acid phosphatase 2, lysosomal (ENSG00000134575), score: 0.56 ACPPacid phosphatase, prostate (ENSG00000014257), score: 0.65 ACYP2acylphosphatase 2, muscle type (ENSG00000170634), score: -0.54 AGPHD1aminoglycoside phosphotransferase domain containing 1 (ENSG00000188266), score: 0.53 AKR1A1aldo-keto reductase family 1, member A1 (aldehyde reductase) (ENSG00000117448), score: 0.54 ANKRA2ankyrin repeat, family A (RFXANK-like), 2 (ENSG00000164331), score: -0.5 ANKRD22ankyrin repeat domain 22 (ENSG00000152766), score: 0.66 ANKS4Bankyrin repeat and sterile alpha motif domain containing 4B (ENSG00000175311), score: 0.58 ANO10anoctamin 10 (ENSG00000160746), score: 0.56 APEHN-acylaminoacyl-peptide hydrolase (ENSG00000164062), score: 0.72 AQP3aquaporin 3 (Gill blood group) (ENSG00000165272), score: 0.83 ARHGEF38Rho guanine nucleotide exchange factor (GEF) 38 (ENSG00000138784), score: 0.66 ASAH1N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ENSG00000104763), score: 0.58 ASPAaspartoacylase (ENSG00000108381), score: 0.59 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.75 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.68 BARX2BARX homeobox 2 (ENSG00000043039), score: 0.61 BDKRB1bradykinin receptor B1 (ENSG00000100739), score: 0.53 BDKRB2bradykinin receptor B2 (ENSG00000168398), score: 0.56 BNC2basonuclin 2 (ENSG00000173068), score: 0.61 C11orf54chromosome 11 open reading frame 54 (ENSG00000182919), score: 0.58 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.64 C22orf28chromosome 22 open reading frame 28 (ENSG00000100220), score: 0.59 C2orf18chromosome 2 open reading frame 18 (ENSG00000213699), score: 0.63 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.63 C8orf84chromosome 8 open reading frame 84 (ENSG00000164764), score: 0.63 CA12carbonic anhydrase XII (ENSG00000074410), score: 0.74 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.77 CASS4Cas scaffolding protein family member 4 (ENSG00000087589), score: 0.65 CCNT2cyclin T2 (ENSG00000082258), score: -0.55 CD151CD151 molecule (Raph blood group) (ENSG00000177697), score: 0.59 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (ENSG00000113361), score: 0.62 CELF2CUGBP, Elav-like family member 2 (ENSG00000048740), score: -0.51 CLCN5chloride channel 5 (ENSG00000171365), score: 0.68 CLDN16claudin 16 (ENSG00000113946), score: 0.75 CLDN19claudin 19 (ENSG00000164007), score: 0.9 CLIC6chloride intracellular channel 6 (ENSG00000159212), score: 0.55 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.72 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.76 CRYAAcrystallin, alpha A (ENSG00000160202), score: 0.57 CRYL1crystallin, lambda 1 (ENSG00000165475), score: 0.6 CTGFconnective tissue growth factor (ENSG00000118523), score: 0.6 CTSHcathepsin H (ENSG00000103811), score: 0.61 CTTNcortactin (ENSG00000085733), score: 0.55 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.76 CYLDcylindromatosis (turban tumor syndrome) (ENSG00000083799), score: -0.57 DAAM1dishevelled associated activator of morphogenesis 1 (ENSG00000100592), score: -0.57 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.74 DAOD-amino-acid oxidase (ENSG00000110887), score: 0.58 DDCdopa decarboxylase (aromatic L-amino acid decarboxylase) (ENSG00000132437), score: 0.62 DDHD1DDHD domain containing 1 (ENSG00000100523), score: -0.5 DHDPSLdihydrodipicolinate synthase-like, mitochondrial (ENSG00000241935), score: 0.59 DLEC1deleted in lung and esophageal cancer 1 (ENSG00000008226), score: 0.58 DPEP1dipeptidase 1 (renal) (ENSG00000015413), score: 0.7 DPP4dipeptidyl-peptidase 4 (ENSG00000197635), score: 0.67 DUSP10dual specificity phosphatase 10 (ENSG00000143507), score: -0.59 EGFepidermal growth factor (ENSG00000138798), score: 0.81 EHFets homologous factor (ENSG00000135373), score: 0.66 ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ENSG00000163435), score: 0.67 ELF5E74-like factor 5 (ets domain transcription factor) (ENSG00000135374), score: 1 ELMO3engulfment and cell motility 3 (ENSG00000102890), score: 0.72 ENPEPglutamyl aminopeptidase (aminopeptidase A) (ENSG00000138792), score: 0.61 EPCAMepithelial cell adhesion molecule (ENSG00000119888), score: 0.55 EPYCepiphycan (ENSG00000083782), score: 0.55 ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ENSG00000141736), score: 0.55 ERCC6excision repair cross-complementing rodent repair deficiency, complementation group 6 (ENSG00000225830), score: -0.53 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.76 EVCEllis van Creveld syndrome (ENSG00000072840), score: 0.62 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.71 FAM102Afamily with sequence similarity 102, member A (ENSG00000167106), score: 0.55 FAM3Bfamily with sequence similarity 3, member B (ENSG00000183844), score: 0.57 FAM3Dfamily with sequence similarity 3, member D (ENSG00000198643), score: 0.64 FAM83Hfamily with sequence similarity 83, member H (ENSG00000180921), score: 0.6 FBXO11F-box protein 11 (ENSG00000138081), score: -0.53 FGFR4fibroblast growth factor receptor 4 (ENSG00000160867), score: 0.6 FOXI1forkhead box I1 (ENSG00000168269), score: 0.84 FRA10AC1fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 (ENSG00000148690), score: -0.55 FRAS1Fraser syndrome 1 (ENSG00000138759), score: 0.63 FRMD6FERM domain containing 6 (ENSG00000139926), score: -0.54 GABRPgamma-aminobutyric acid (GABA) A receptor, pi (ENSG00000094755), score: 0.74 GALK2galactokinase 2 (ENSG00000156958), score: 0.58 GALNT14UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (ENSG00000158089), score: 0.7 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.76 GCM1glial cells missing homolog 1 (Drosophila) (ENSG00000137270), score: 0.9 GOPCgolgi-associated PDZ and coiled-coil motif containing (ENSG00000047932), score: -0.64 GPR114G protein-coupled receptor 114 (ENSG00000159618), score: 0.92 GPR56G protein-coupled receptor 56 (ENSG00000205336), score: 0.65 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.74 GSCgoosecoid homeobox (ENSG00000133937), score: 0.68 HDAC9histone deacetylase 9 (ENSG00000048052), score: -0.5 HNF1AHNF1 homeobox A (ENSG00000135100), score: 0.6 HOXA10homeobox A10 (ENSG00000153807), score: 0.72 HOXB7homeobox B7 (ENSG00000120087), score: 0.7 HOXD10homeobox D10 (ENSG00000128710), score: 0.61 HOXD4homeobox D4 (ENSG00000170166), score: 0.77 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.72 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.85 ITM2Bintegral membrane protein 2B (ENSG00000136156), score: 0.65 KCNE3potassium voltage-gated channel, Isk-related family, member 3 (ENSG00000175538), score: 0.65 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.81 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.57 KCNK5potassium channel, subfamily K, member 5 (ENSG00000164626), score: 0.72 KIF12kinesin family member 12 (ENSG00000136883), score: 0.6 KIF13Bkinesin family member 13B (ENSG00000197892), score: 0.64 KIF2Akinesin heavy chain member 2A (ENSG00000068796), score: -0.5 KLklotho (ENSG00000133116), score: 0.73 KLHDC7Akelch domain containing 7A (ENSG00000179023), score: 0.64 KRT23keratin 23 (histone deacetylase inducible) (ENSG00000108244), score: 0.61 LAD1ladinin 1 (ENSG00000159166), score: 0.54 LAMC3laminin, gamma 3 (ENSG00000050555), score: 0.59 LGALS2lectin, galactoside-binding, soluble, 2 (ENSG00000100079), score: 0.78 LGMNlegumain (ENSG00000100600), score: 0.54 LLGL2lethal giant larvae homolog 2 (Drosophila) (ENSG00000073350), score: 0.65 LMX1BLIM homeobox transcription factor 1, beta (ENSG00000136944), score: 0.64 MALmal, T-cell differentiation protein (ENSG00000172005), score: 0.53 MAN2B2mannosidase, alpha, class 2B, member 2 (ENSG00000013288), score: 0.53 MAPK13mitogen-activated protein kinase 13 (ENSG00000156711), score: 0.53 MARVELD3MARVEL domain containing 3 (ENSG00000140832), score: 0.63 MED17mediator complex subunit 17 (ENSG00000042429), score: -0.53 MPP1membrane protein, palmitoylated 1, 55kDa (ENSG00000130830), score: 0.55 MSRAmethionine sulfoxide reductase A (ENSG00000175806), score: 0.6 MTMR14myotubularin related protein 14 (ENSG00000163719), score: 0.65 MYH9myosin, heavy chain 9, non-muscle (ENSG00000100345), score: 0.53 NCSTNnicastrin (ENSG00000162736), score: 0.54 NMT2N-myristoyltransferase 2 (ENSG00000152465), score: -0.5 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.86 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 0.79 NPNTnephronectin (ENSG00000168743), score: 0.63 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.63 OLFM4olfactomedin 4 (ENSG00000102837), score: 0.63 OSBPL3oxysterol binding protein-like 3 (ENSG00000070882), score: 0.54 PAIP2poly(A) binding protein interacting protein 2 (ENSG00000120727), score: -0.58 PAPPApregnancy-associated plasma protein A, pappalysin 1 (ENSG00000182752), score: 0.67 PAPPA2pappalysin 2 (ENSG00000116183), score: 0.76 PAQR5progestin and adipoQ receptor family member V (ENSG00000137819), score: 0.61 PDS5BPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) (ENSG00000083642), score: -0.53 PEPDpeptidase D (ENSG00000124299), score: 0.76 PFKLphosphofructokinase, liver (ENSG00000141959), score: 0.64 PKD2polycystic kidney disease 2 (autosomal dominant) (ENSG00000118762), score: 0.6 PLATplasminogen activator, tissue (ENSG00000104368), score: 0.59 PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific) (ENSG00000197943), score: 0.57 PLEKHJ1pleckstrin homology domain containing, family J member 1 (ENSG00000104886), score: 0.67 PQLC3PQ loop repeat containing 3 (ENSG00000162976), score: 0.54 PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit (ENSG00000111725), score: 0.67 PRKACBprotein kinase, cAMP-dependent, catalytic, beta (ENSG00000142875), score: -0.52 PROM2prominin 2 (ENSG00000155066), score: 0.78 PTPRQprotein tyrosine phosphatase, receptor type, Q (ENSG00000139304), score: 0.56 PTRH2peptidyl-tRNA hydrolase 2 (ENSG00000141378), score: -0.53 QARSglutaminyl-tRNA synthetase (ENSG00000172053), score: 0.56 RAB17RAB17, member RAS oncogene family (ENSG00000124839), score: 0.66 RAB19RAB19, member RAS oncogene family (ENSG00000146955), score: 0.53 RB1CC1RB1-inducible coiled-coil 1 (ENSG00000023287), score: -0.56 RFXANKregulatory factor X-associated ankyrin-containing protein (ENSG00000064490), score: 0.62 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.8 RNF152ring finger protein 152 (ENSG00000176641), score: 0.56 SACSspastic ataxia of Charlevoix-Saguenay (sacsin) (ENSG00000151835), score: -0.5 SCINscinderin (ENSG00000006747), score: 0.8 SCNN1Asodium channel, nonvoltage-gated 1 alpha (ENSG00000111319), score: 0.75 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.88 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.82 SDSLserine dehydratase-like (ENSG00000139410), score: 0.57 SEMA3Fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (ENSG00000001617), score: 0.61 SESN1sestrin 1 (ENSG00000080546), score: -0.49 SFXN2sideroflexin 2 (ENSG00000156398), score: 0.58 SGK1serum/glucocorticoid regulated kinase 1 (ENSG00000118515), score: 0.53 SGK2serum/glucocorticoid regulated kinase 2 (ENSG00000101049), score: 0.6 SH3BP5SH3-domain binding protein 5 (BTK-associated) (ENSG00000131370), score: 0.53 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.69 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.7 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.78 SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (ENSG00000158296), score: 0.65 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (ENSG00000088386), score: 0.67 SLC16A12solute carrier family 16, member 12 (monocarboxylic acid transporter 12) (ENSG00000152779), score: 0.57 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.77 SLC19A1solute carrier family 19 (folate transporter), member 1 (ENSG00000173638), score: 0.65 SLC22A7solute carrier family 22 (organic anion transporter), member 7 (ENSG00000137204), score: 0.57 SLC25A10solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 (ENSG00000183048), score: 0.57 SLC25A42solute carrier family 25, member 42 (ENSG00000181035), score: 0.55 SLC26A7solute carrier family 26, member 7 (ENSG00000147606), score: 0.72 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.75 SLC3A1solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 (ENSG00000138079), score: 0.6 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.91 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 0.82 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.86 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.81 SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 3 (ENSG00000066230), score: 0.63 SLC9A4solute carrier family 9 (sodium/hydrogen exchanger), member 4 (ENSG00000180251), score: 0.61 SMCHD1structural maintenance of chromosomes flexible hinge domain containing 1 (ENSG00000101596), score: -0.55 SOX13SRY (sex determining region Y)-box 13 (ENSG00000143842), score: 0.54 SPP1secreted phosphoprotein 1 (ENSG00000118785), score: 0.59 ST14suppression of tumorigenicity 14 (colon carcinoma) (ENSG00000149418), score: 0.63 STAP1signal transducing adaptor family member 1 (ENSG00000035720), score: 0.86 STC1stanniocalcin 1 (ENSG00000159167), score: 0.77 SUCLG1succinate-CoA ligase, alpha subunit (ENSG00000163541), score: 0.62 SULF2sulfatase 2 (ENSG00000196562), score: 0.57 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.93 SUSD3sushi domain containing 3 (ENSG00000157303), score: 0.58 TBC1D1TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 (ENSG00000065882), score: 0.53 TBX2T-box 2 (ENSG00000121068), score: 0.59 TCN2transcobalamin II (ENSG00000185339), score: 0.66 TEX264testis expressed 264 (ENSG00000164081), score: 0.64 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.82 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.62 TM7SF3transmembrane 7 superfamily member 3 (ENSG00000064115), score: 0.62 TMCO4transmembrane and coiled-coil domains 4 (ENSG00000162542), score: 0.66 TMEM120Btransmembrane protein 120B (ENSG00000188735), score: 0.55 TMEM138transmembrane protein 138 (ENSG00000149483), score: 0.6 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.66 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.68 TMEM51transmembrane protein 51 (ENSG00000171729), score: 0.58 TMIGD1transmembrane and immunoglobulin domain containing 1 (ENSG00000182271), score: 0.54 TMPRSS13transmembrane protease, serine 13 (ENSG00000137747), score: 0.65 TMPRSS2transmembrane protease, serine 2 (ENSG00000184012), score: 0.63 TMPRSS4transmembrane protease, serine 4 (ENSG00000137648), score: 0.54 TPP2tripeptidyl peptidase II (ENSG00000134900), score: -0.55 TRPM6transient receptor potential cation channel, subfamily M, member 6 (ENSG00000119121), score: 0.61 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.73 TTF2transcription termination factor, RNA polymerase II (ENSG00000116830), score: 0.55 UNC45Aunc-45 homolog A (C. elegans) (ENSG00000140553), score: 0.6 UPK3Auroplakin 3A (ENSG00000100373), score: 0.84 WARS2tryptophanyl tRNA synthetase 2, mitochondrial (ENSG00000116874), score: 0.6 WDR1WD repeat domain 1 (ENSG00000071127), score: 0.55 WDR72WD repeat domain 72 (ENSG00000166415), score: 0.8 WDR91WD repeat domain 91 (ENSG00000105875), score: 0.59 XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (ENSG00000122121), score: 0.88 YAF2YY1 associated factor 2 (ENSG00000015153), score: -0.53 ZBTB11zinc finger and BTB domain containing 11 (ENSG00000066422), score: -0.55 ZBTB43zinc finger and BTB domain containing 43 (ENSG00000169155), score: -0.54 ZDHHC20zinc finger, DHHC-type containing 20 (ENSG00000180776), score: -0.57 ZNF518Bzinc finger protein 518B (ENSG00000178163), score: -0.52 ZNF618zinc finger protein 618 (ENSG00000157657), score: 0.57 ZNF644zinc finger protein 644 (ENSG00000122482), score: -0.6 ZPLD1zona pellucida-like domain containing 1 (ENSG00000170044), score: 0.69

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
hsa_kd_f_ca1	hsa	kd	f	_
hsa_kd_m2_ca1	hsa	kd	m	2
mdo_kd_m_ca1	mdo	kd	m	_
hsa_kd_m1_ca1	hsa	kd	m	1
mdo_kd_f_ca1	mdo	kd	f	_