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system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

organic acid transport

The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of, within or between cells by means of some external agent such as a transporter or pore.

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

epithelial cell differentiation

The process whereby a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

carboxylic acid transport

The directed movement of carboxylic acids into, out of, within or between cells by means of some external agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

epithelium development

The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.

all

NA

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

epithelial cell differentiation

The process whereby a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

basolateral plasma membrane

The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

sodium channel complex

An ion channel complex through which sodium ions pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

organic acid transmembrane transporter activity

Catalysis of the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

anion transmembrane transporter activity

Catalysis of the transfer of a negatively charged ion from one side of a membrane to the other.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

symporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

carboxylic acid transmembrane transporter activity

Catalysis of the transfer of carboxylic acids from one side of the membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0007588	4.631e-09	1.092	13 AQP3, ATP6V0A4, AVPR1A, CLCN5, CLDN16, DAB2, KCNJ1, KCNK5, NPHS2, NPR3, SCNN1A, SCNN1B, SCNN1G	24	excretion
GO:0006814	3.761e-06	2.139	14 SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC9A3	47	sodium ion transport
GO:0006811	4.232e-05	15.11	37 ABCC4, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, CNNM2, EGF, GABRP, KCNJ1, KCNJ16, KCNK5, PKD2, PLCG2, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC22A7, SLC26A7, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC9A3, TCN2, TRPM6, TRPV4, WNK1	332	ion transport
GO:0046903	7.787e-05	8.737	26 AGR2, AGXT, AQP3, ATP6V0A4, AVPR1A, CD40LG, CLCN5, CLDN16, DAB2, EGF, FAM3D, GHRHR, HNF1A, KCNJ1, KCNK5, LLGL2, NPHS2, NPR3, PRLR, SCIN, SCNN1A, SCNN1B, SCNN1G, SLC22A4, TNFSF15, TRPV4	192	secretion
GO:0015672	9.783e-05	5.097	19 ATP6V0A4, ATP6V0D2, KCNJ1, KCNJ16, KCNK5, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC9A3	112	monovalent inorganic cation transport
GO:0006812	1.763e-04	10.38	28 ATP6V0A4, ATP6V0D2, EGF, KCNJ1, KCNJ16, KCNK5, PKD2, PLCG2, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC9A3, TCN2, TRPM6, TRPV4	228	cation transport
GO:0030855	5.118e-04	2.867	13 AQP3, EHF, ELF3, ELF5, EREG, IRF6, JAG1, LAMA1, RHCG, SALL1, TFCP2L1, UPK3A, ZEB1	63	epithelial cell differentiation
GO:0030001	1.059e-03	9.056	24 EGF, KCNJ1, KCNJ16, KCNK5, PKD2, PLCG2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC9A3, TCN2, TRPM6, TRPV4	199	metal ion transport
GO:0051179	2.263e-03	57.06	84 ABCC4, AGR2, AGXT, AP1G1, AP1S3, AQP3, ARSB, ATP6V0A4, ATP6V0D2, AVPR1A, BAMBI, CD40LG, CLCN5, CLDN16, CLIC6, CNNM2, CUBN, CYBASC3, DAB2, DPP4, EGF, ELMO3, ENPEP, F2RL1, FAM3D, FERMT1, GABRP, GHRHR, GOPC, HNF1A, IL12B, JAG1, KCNJ1, KCNJ16, KCNK5, LAMA1, LLGL2, LMX1B, NPHS2, NPR3, OSTalpha, PKD2, PLCG2, PRLR, RAB19, RAB7L1, REEP1, RHAG, RHCG, SCAMP2, SCIN, SCNN1A, SCNN1B, SCNN1G, SEMA3F, SFXN2, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC25A48, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, TCN2, TNFSF15, TRPM6, TRPV4, UPK3A, WNK1	1254	localization
GO:0055085	4.094e-03	12.65	28 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, EGF, PKD2, PLCG2, RHAG, RHCG, SFXN2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC25A48, SLC26A7, SLC5A11, SLC5A12, SLC5A9, SLC7A9, SLC9A3, TRPM6, TRPV4	278	transmembrane transport
GO:0051234	4.297e-03	49.28	74 ABCC4, AGR2, AGXT, AP1G1, AP1S3, AQP3, ARSB, ATP6V0A4, ATP6V0D2, AVPR1A, CD40LG, CLCN5, CLDN16, CLIC6, CNNM2, CUBN, CYBASC3, DAB2, DPP4, EGF, ELMO3, FAM3D, GABRP, GHRHR, GOPC, HNF1A, KCNJ1, KCNJ16, KCNK5, LLGL2, NPHS2, NPR3, OSTalpha, PKD2, PLCG2, PRLR, RAB19, RAB7L1, RHAG, RHCG, SCAMP2, SCIN, SCNN1A, SCNN1B, SCNN1G, SFXN2, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC25A48, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, TCN2, TNFSF15, TRPM6, TRPV4, UPK3A, WNK1	1083	establishment of localization
GO:0015849	4.568e-03	3.14	12 AGXT, HNF1A, SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC22A4, SLC25A10, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	organic acid transport
GO:0046942	4.568e-03	3.14	12 AGXT, HNF1A, SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC22A4, SLC25A10, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	carboxylic acid transport
GO:0006810	5.225e-03	48.74	73 ABCC4, AGR2, AGXT, AP1G1, AP1S3, AQP3, ARSB, ATP6V0A4, ATP6V0D2, AVPR1A, CD40LG, CLCN5, CLDN16, CLIC6, CNNM2, CUBN, CYBASC3, DAB2, EGF, ELMO3, FAM3D, GABRP, GHRHR, GOPC, HNF1A, KCNJ1, KCNJ16, KCNK5, LLGL2, NPHS2, NPR3, OSTalpha, PKD2, PLCG2, PRLR, RAB19, RAB7L1, RHAG, RHCG, SCAMP2, SCIN, SCNN1A, SCNN1B, SCNN1G, SFXN2, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC25A48, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, TCN2, TNFSF15, TRPM6, TRPV4, UPK3A, WNK1	1071	transport
GO:0060429	1.180e-02	6.371	17 AQP3, EHF, ELF3, ELF5, EREG, FZD6, GCM1, IRF6, JAG1, LAMA1, NTN4, RHCG, SALL1, TFAP2A, TFCP2L1, UPK3A, ZEB1	140	epithelium development
GO:0048704	1.266e-02	0.9101	6 GSC, HOXB7, HOXD10, HOXD4, TFAP2A, ZEB1	20	embryonic skeletal system morphogenesis
GO:0006082	1.438e-02	10.38	23 ACAD8, ACMSD, ACSM3, AGXT, AKR1A1, ALDH6A1, ASPA, AVPR1A, DAO, DDC, DMGDH, DPYS, HAO2, HNF1A, HNF4A, PCK1, PCK2, PEPD, SDSL, SLC22A4, SLC25A10, SLC3A1, SLC7A9	228	organic acid metabolic process
GO:0019752	1.438e-02	10.38	23 ACAD8, ACMSD, ACSM3, AGXT, AKR1A1, ALDH6A1, ASPA, AVPR1A, DAO, DDC, DMGDH, DPYS, HAO2, HNF1A, HNF4A, PCK1, PCK2, PEPD, SDSL, SLC22A4, SLC25A10, SLC3A1, SLC7A9	228	carboxylic acid metabolic process
GO:0043436	1.438e-02	10.38	23 ACAD8, ACMSD, ACSM3, AGXT, AKR1A1, ALDH6A1, ASPA, AVPR1A, DAO, DDC, DMGDH, DPYS, HAO2, HNF1A, HNF4A, PCK1, PCK2, PEPD, SDSL, SLC22A4, SLC25A10, SLC3A1, SLC7A9	228	oxoacid metabolic process
GO:0046849	1.667e-02	0.6371	5 HNF1A, NOX4, RAC2, SLC34A1, TPP1	14	bone remodeling
GO:0042180	1.844e-02	10.6	23 ACAD8, ACMSD, ACSM3, AGXT, AKR1A1, ALDH6A1, ASPA, AVPR1A, DAO, DDC, DMGDH, DPYS, HAO2, HNF1A, HNF4A, PCK1, PCK2, PEPD, SDSL, SLC22A4, SLC25A10, SLC3A1, SLC7A9	233	cellular ketone metabolic process
GO:0048562	2.282e-02	2.321	9 FOXI1, FZD6, GSC, HOXB7, HOXD10, HOXD4, SALL1, TFAP2A, ZEB1	51	embryonic organ morphogenesis
GO:0044106	2.952e-02	5.188	14 ACAD8, AGXT, ALDH6A1, ASPA, DAO, DDC, DMGDH, DPYS, HNF4A, PEPD, SDSL, SLC22A4, SLC3A1, SLC7A9	114	cellular amine metabolic process
GO:0006520	3.328e-02	4.096	12 ACAD8, AGXT, ALDH6A1, ASPA, DAO, DMGDH, DPYS, HNF4A, PEPD, SDSL, SLC3A1, SLC7A9	90	cellular amino acid metabolic process
GO:0006519	3.917e-02	6.007	15 A2LD1, ACAD8, AGXT, ALDH6A1, ASPA, DAO, DDC, DMGDH, DPYS, HNF4A, PEPD, SDSL, SLC22A4, SLC3A1, SLC7A9	132	cellular amino acid and derivative metabolic process
GO:0003084	3.993e-02	0.2275	3 AVPR1A, HSD11B2, WNK1	5	positive regulation of systemic arterial blood pressure
GO:0030879	4.367e-02	1.638	7 EGF, ELF3, ELF5, GHRHR, IRF6, PRLR, TBX2	36	mammary gland development
GO:0006835	4.630e-02	0.5006	4 AGXT, SLC13A3, SLC25A10, SLC26A7	11	dicarboxylic acid transport

Id	Pvalue	ExpCount	Count	Size	Term
GO:0045177	1.101e-10	3.311	22 AKR1A1, ATP6V0A4, ATP6V0D2, CLCN5, CUBN, DPEP1, DPP4, ENPEP, EPCAM, FZD6, LGMN, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC22A4, SLC5A12, SLC9A3, TRPM6, UPK3A	75	apical part of cell
GO:0016324	6.490e-10	2.605	19 AKR1A1, ATP6V0A4, ATP6V0D2, CUBN, DPEP1, DPP4, ENPEP, EPCAM, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC22A4, SLC5A12, SLC9A3, TRPM6, UPK3A	59	apical plasma membrane
GO:0044459	9.252e-06	31.83	61 AKR1A1, AQP3, ATP6V0A4, ATP6V0D2, AVPR1A, CASR, CASS4, CD40LG, CLCN5, CLDN16, CLDN19, CUBN, DNMBP, DPEP1, DPP4, ENPEP, EPCAM, EREG, F2RL1, FERMT1, FZD6, GABRP, GOPC, ITGB4, JAG1, KCNJ1, KCNJ16, KCNK5, KL, MARVELD2, MYO1D, NOX4, NPHS2, PROM2, RASA3, RHAG, RHCG, RXFP3, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC26A7, SLC34A1, SLC3A1, SLC4A4, SLC5A12, SLC6A19, SLC7A9, SLC9A3, ST14, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A	721	plasma membrane part
GO:0005886	1.386e-05	50.02	83 ABCC4, AKR1A1, ANKS4B, APLP2, AQP3, ATP6V0A4, ATP6V0D2, AVPR1A, BAMBI, CASR, CASS4, CD40LG, CLCN5, CLDN16, CLDN19, CLIC6, CUBN, DNMBP, DPEP1, DPP4, EGF, ENPEP, EPCAM, EREG, F2RL1, FERMT1, FRAS1, FZD6, GABRP, GHRHR, GOPC, GRK5, ILDR1, ITGB4, JAG1, KCNJ1, KCNJ16, KCNK5, KIRREL, KL, MARVELD2, MYO1D, NOX4, NPHS2, OSTalpha, PKD2, PLCG2, PROM2, PTGER4, RAB19, RAB7L1, RASA3, RHAG, RHCG, RXFP3, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC26A7, SLC34A1, SLC3A1, SLC4A4, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, ST14, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A, XPNPEP2	1133	plasma membrane
GO:0005903	2.725e-04	0.7947	7 ATP6V0A4, CUBN, ENPEP, SLC13A1, SLC34A1, SLC9A3, TRPM6	18	brush border
GO:0031253	4.778e-04	1.898	10 ATP6V0A4, CUBN, DPEP1, DPP4, FERMT1, MYO1D, PROM2, SLC34A1, SLC9A3, TRPM6	43	cell projection membrane
GO:0031224	1.443e-03	71.39	99 ABCC4, APLP2, AQP3, ATP6V0A4, AVPR1A, BAMBI, CASR, CD40LG, CLCN5, CLDN16, CLDN19, CLIC6, CNNM2, CYBASC3, DPEP1, DPP4, EGF, ENPEP, EPCAM, EREG, EVC, F2RL1, FRAS1, FZD6, GABRP, GALNT11, GALNT14, GHRHR, GRAMD2, ILDR1, ITGB4, JAG1, KCNJ1, KCNJ16, KCNK5, KIRREL, KL, KLHDC7A, MARVELD2, MARVELD3, MPZL2, NOX4, NPHS2, NPR3, OSTalpha, PAQR5, PKD2, PRLR, PROM2, PTGER4, PTPRQ, RASA3, REEP1, RHAG, RHCG, RXFP3, SCAMP2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SHISA2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC25A48, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC44A3, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, ST14, SUSD2, SUSD3, TMEM171, TMEM27, TMEM51, TMIGD1, TMPRSS13, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A, XPNPEP2, ZPLD1	1617	intrinsic to membrane
GO:0034706	2.451e-03	0.1325	3 SCNN1A, SCNN1B, SCNN1G	3	sodium channel complex
GO:0016021	2.850e-03	69.93	96 ABCC4, APLP2, AQP3, ATP6V0A4, AVPR1A, BAMBI, CASR, CD40LG, CLCN5, CLDN16, CLDN19, CLIC6, CNNM2, CYBASC3, DPP4, EGF, ENPEP, EPCAM, EREG, EVC, F2RL1, FRAS1, FZD6, GABRP, GALNT11, GALNT14, GHRHR, GRAMD2, ILDR1, ITGB4, JAG1, KCNJ1, KCNJ16, KCNK5, KIRREL, KL, KLHDC7A, MARVELD2, MARVELD3, MPZL2, NOX4, NPHS2, NPR3, OSTalpha, PAQR5, PKD2, PRLR, PROM2, PTGER4, PTPRQ, REEP1, RHAG, RHCG, RXFP3, SCAMP2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SHISA2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC25A48, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC44A3, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, ST14, SUSD2, SUSD3, TMEM171, TMEM27, TMEM51, TMIGD1, TMPRSS13, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A, ZPLD1	1584	integral to membrane
GO:0044425	3.897e-03	83.84	110 ABCC4, AKR1A1, AP1G1, AP1S3, APLP2, AQP3, ATP6V0A4, ATP6V0D2, AVPR1A, BAMBI, CASR, CASS4, CD40LG, CLCN5, CLDN16, CLDN19, CLIC6, CNNM2, CUBN, CYBASC3, DAB2, DNMBP, DPEP1, DPP4, EGF, ENPEP, EPCAM, EREG, EVC, F2RL1, FERMT1, FRAS1, FZD6, GABRP, GALNT11, GALNT14, GHRHR, GOPC, GRAMD2, ILDR1, ITGB4, JAG1, KCNJ1, KCNJ16, KCNK5, KIRREL, KL, KLHDC7A, MARVELD2, MARVELD3, MPZL2, MYO1D, NOX4, NPHS2, NPR3, OSTalpha, PAQR5, PKD2, PRLR, PROM2, PTGER4, PTPRQ, RASA3, REEP1, RHAG, RHCG, RXFP3, SCAMP2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SHISA2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC25A48, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC44A3, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, ST14, SUSD2, SUSD3, TMEM171, TMEM27, TMEM51, TMIGD1, TMPRSS13, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A, XPNPEP2, ZPLD1	1899	membrane part
GO:0031526	3.981e-03	0.574	5 ATP6V0A4, CUBN, SLC34A1, SLC9A3, TRPM6	13	brush border membrane
GO:0016323	4.331e-03	4.062	13 AQP3, CASS4, CLDN19, EPCAM, FERMT1, ITGB4, NOX4, PROM2, RHCG, SLC22A7, SLC26A7, SLC4A4, ST14	92	basolateral plasma membrane
GO:0005604	1.168e-02	1.501	7 COL4A3, COL4A4, LAD1, LAMA1, LAMC3, NTN4, TINAG	34	basement membrane
GO:0031226	1.466e-02	18.68	33 AVPR1A, CASR, CD40LG, CLCN5, ENPEP, EREG, F2RL1, FZD6, ITGB4, JAG1, KCNJ1, KCNJ16, KCNK5, KL, NPHS2, RASA3, RHAG, RHCG, RXFP3, SCNN1G, SLC10A2, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC34A1, SLC3A1, SLC4A4, SLC6A19, SLC7A9, ST14, TMPRSS2, TNFSF15	423	intrinsic to plasma membrane
GO:0005887	1.873e-02	18.23	32 AVPR1A, CASR, CD40LG, CLCN5, ENPEP, EREG, F2RL1, FZD6, ITGB4, JAG1, KCNJ1, KCNJ16, KCNK5, KL, NPHS2, RHAG, RHCG, RXFP3, SCNN1G, SLC10A2, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC34A1, SLC3A1, SLC4A4, SLC6A19, SLC7A9, ST14, TMPRSS2, TNFSF15	413	integral to plasma membrane
GO:0016471	3.078e-02	0.0883	2 ATP6V0A4, ATP6V0D2	2	vacuolar proton-transporting V-type ATPase complex
GO:0044420	3.666e-02	1.898	7 COL4A3, COL4A4, LAD1, LAMA1, LAMC3, NTN4, TINAG	43	extracellular matrix part
GO:0016020	4.274e-02	102.7	123 ABCC4, AKR1A1, ANKS4B, AP1G1, AP1S3, APLP2, AQP3, ASAP1, ATP6V0A4, ATP6V0D2, AVPR1A, BAMBI, CASR, CASS4, CD40LG, CLCN5, CLDN16, CLDN19, CLIC6, CNNM2, CUBN, CYBASC3, DAB2, DNMBP, DPEP1, DPP4, EGF, ENPEP, EPCAM, EREG, EVC, F2RL1, FERMT1, FRAS1, FZD6, GABRP, GALNT11, GALNT14, GHRHR, GOPC, GRAMD2, GRK5, IL12B, ILDR1, ITGB4, JAG1, KCNJ1, KCNJ16, KCNK5, KIRREL, KL, KLHDC7A, LAMC3, MARVELD2, MARVELD3, MPZL2, MYO1D, NOX4, NPHS2, NPNT, NPR3, OSTalpha, PAQR5, PKD2, PLCG2, PRLR, PROM2, PTGER4, PTPRQ, RAB19, RAB7L1, RASA3, REEP1, RHAG, RHCG, RIPK4, RXFP3, SCAMP2, SCNN1A, SCNN1B, SCNN1G, SEMA3F, SFXN2, SGK1, SHISA2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC25A48, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC44A3, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, ST14, SUSD2, SUSD3, TFCP2L1, TMEM171, TMEM27, TMEM51, TMIGD1, TMPRSS13, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A, XPNPEP2, ZPLD1	2327	membrane

Id	Pvalue	ExpCount	Count	Size	Term
GO:0022857	2.149e-05	16.45	40 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, GABRP, KCNJ1, KCNJ16, KCNK5, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC26A7, SLC34A1, SLC3A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, TRPM6, TRPV4	368	transmembrane transporter activity
GO:0015291	3.235e-05	3.754	17 CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC26A7, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC9A3	84	secondary active transmembrane transporter activity
GO:0005215	3.913e-05	20.29	45 ABCC4, AP1G1, AP1S3, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, CUBN, GABRP, KCNJ1, KCNJ16, KCNK5, OSTalpha, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC25A48, SLC26A7, SLC34A1, SLC3A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, TRPM6, TRPV4	454	transporter activity
GO:0022804	5.185e-05	5.81	21 ABCC4, ATP6V0A4, CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC26A7, SLC34A1, SLC3A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3	130	active transmembrane transporter activity
GO:0022891	6.226e-05	15.29	37 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, GABRP, KCNJ1, KCNJ16, KCNK5, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC26A7, SLC34A1, SLC3A1, SLC4A4, SLC5A9, SLC6A19, SLC7A9, SLC9A3, TRPM6, TRPV4	342	substrate-specific transmembrane transporter activity
GO:0015293	1.394e-04	2.503	13 SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC22A4, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19	56	symporter activity
GO:0022892	1.538e-04	17.34	39 ABCC4, AP1G1, AP1S3, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, GABRP, KCNJ1, KCNJ16, KCNK5, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A2, SLC16A4, SLC22A4, SLC22A7, SLC25A10, SLC26A7, SLC34A1, SLC3A1, SLC4A4, SLC5A9, SLC6A19, SLC7A9, SLC9A3, TRPM6, TRPV4	388	substrate-specific transporter activity
GO:0015075	8.382e-04	13.41	31 ABCC4, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, GABRP, KCNJ1, KCNJ16, KCNK5, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC22A7, SLC26A7, SLC34A1, SLC4A4, SLC5A9, SLC6A19, SLC9A3, TRPM6, TRPV4	300	ion transmembrane transporter activity
GO:0022890	2.520e-03	3.441	13 ATP6V0A4, ATP6V0D2, CLDN16, RHAG, RHCG, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC4A4, SLC5A9, SLC6A19, SLC9A3	77	inorganic cation transmembrane transporter activity
GO:0005342	3.199e-03	1.743	9 SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC25A10, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	organic acid transmembrane transporter activity
GO:0046943	3.199e-03	1.743	9 SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC25A10, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	carboxylic acid transmembrane transporter activity
GO:0008324	4.355e-03	10.15	24 ATP6V0A4, ATP6V0D2, CLDN16, KCNJ1, KCNJ16, KCNK5, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC4A4, SLC5A9, SLC6A19, SLC9A3, TRPM6, TRPV4	227	cation transmembrane transporter activity
GO:0008509	7.452e-03	2.905	11 ABCC4, CLCN5, CLIC6, GABRP, PKD2, SLC13A1, SLC13A3, SLC22A7, SLC26A7, SLC34A1, SLC4A4	65	anion transmembrane transporter activity
GO:0015101	1.670e-02	0.1788	3 RHAG, RHCG, SLC22A4	4	organic cation transmembrane transporter activity
GO:0015280	1.670e-02	0.1788	3 SCNN1A, SCNN1B, SCNN1G	4	amiloride-sensitive sodium channel activity
GO:0003700	1.996e-02	12.96	26 EHF, ELF3, ELF5, FOXI1, GATA3, GCM1, GRHL2, GSC, HNF1A, HNF4A, HNF4G, HOXA10, HOXB7, HOXD10, HOXD4, IRF6, IRX2, LMX1B, SALL1, SIM1, SIM2, TBX2, TFAP2A, TFAP2B, TFCP2L1, ZEB1	290	sequence-specific DNA binding transcription factor activity
GO:0016831	2.737e-02	0.4469	4 ACMSD, DDC, PCK1, PCK2	10	carboxy-lyase activity
GO:0015077	3.257e-02	2.548	9 ATP6V0A4, ATP6V0D2, SLC10A2, SLC13A1, SLC13A3, SLC4A4, SLC5A9, SLC6A19, SLC9A3	57	monovalent inorganic cation transmembrane transporter activity
GO:0005272	3.700e-02	0.4916	4 PKD2, SCNN1A, SCNN1B, SCNN1G	11	sodium channel activity
GO:0008238	3.841e-02	1.654	7 DPEP1, DPP4, ENPEP, PEPD, TMEM27, TPP1, XPNPEP2	37	exopeptidase activity
GO:0043565	4.738e-02	8.983	19 EHF, ELF3, ELF5, FOXI1, GATA3, GSC, HNF1A, HNF4A, HNF4G, HOXA10, HOXB7, HOXD10, HOXD4, IRX2, LMX1B, PRDM16, TBX2, TFAP2B, ZEB1	201	sequence-specific DNA binding

Id	Pvalue	ExpCount	Count	Size	Term
04964	8.996e-04	0.3619	5 PCK1, PCK2, SLC25A10, SLC4A4, SLC9A3	8	Proximal tubule bicarbonate reclamation
04960	3.164e-03	0.7238	6 HSD11B2, KCNJ1, SCNN1A, SCNN1B, SCNN1G, SGK1	16	Aldosterone-regulated sodium reabsorption

No enriched terms

No enriched terms

Entrez genes

A2LD1AIG2-like domain 1 (ENSG00000134864), score: 0.57 ABCC4ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ENSG00000125257), score: 0.55 ACAD8acyl-CoA dehydrogenase family, member 8 (ENSG00000151498), score: 0.49 ACMSDaminocarboxymuconate semialdehyde decarboxylase (ENSG00000153086), score: 0.54 ACSM3acyl-CoA synthetase medium-chain family member 3 (ENSG00000005187), score: 0.55 AGPHD1aminoglycoside phosphotransferase domain containing 1 (ENSG00000188266), score: 0.59 AGR2anterior gradient homolog 2 (Xenopus laevis) (ENSG00000106541), score: 0.64 AGXTalanine-glyoxylate aminotransferase (ENSG00000172482), score: 0.51 AKR1A1aldo-keto reductase family 1, member A1 (aldehyde reductase) (ENSG00000117448), score: 0.49 ALDH6A1aldehyde dehydrogenase 6 family, member A1 (ENSG00000119711), score: 0.56 ANAPC4anaphase promoting complex subunit 4 (ENSG00000053900), score: -0.5 ANKRD22ankyrin repeat domain 22 (ENSG00000152766), score: 0.63 ANKS4Bankyrin repeat and sterile alpha motif domain containing 4B (ENSG00000175311), score: 0.67 AP1G1adaptor-related protein complex 1, gamma 1 subunit (ENSG00000166747), score: 0.52 AP1S3adaptor-related protein complex 1, sigma 3 subunit (ENSG00000152056), score: 0.51 APLP2amyloid beta (A4) precursor-like protein 2 (ENSG00000084234), score: 0.51 AQP3aquaporin 3 (Gill blood group) (ENSG00000165272), score: 0.63 ARHGEF38Rho guanine nucleotide exchange factor (GEF) 38 (ENSG00000138784), score: 0.5 ARPC5Lactin related protein 2/3 complex, subunit 5-like (ENSG00000136950), score: -0.5 ARSBarylsulfatase B (ENSG00000113273), score: 0.51 ASAH1N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ENSG00000104763), score: 0.57 ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ENSG00000153317), score: -0.46 ASPAaspartoacylase (ENSG00000108381), score: 0.69 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.81 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.68 AVPR1Aarginine vasopressin receptor 1A (ENSG00000166148), score: 0.52 BAMBIBMP and activin membrane-bound inhibitor homolog (Xenopus laevis) (ENSG00000095739), score: 0.57 BMP3bone morphogenetic protein 3 (ENSG00000152785), score: 0.53 C11orf54chromosome 11 open reading frame 54 (ENSG00000182919), score: 0.5 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.78 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.72 C4orf31chromosome 4 open reading frame 31 (ENSG00000173376), score: 0.48 CALML4calmodulin-like 4 (ENSG00000129007), score: 0.56 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.83 CASS4Cas scaffolding protein family member 4 (ENSG00000087589), score: 0.75 CD40LGCD40 ligand (ENSG00000102245), score: 0.52 CDC123cell division cycle 123 homolog (S. cerevisiae) (ENSG00000151465), score: -0.53 CELF2CUGBP, Elav-like family member 2 (ENSG00000048740), score: -0.52 CLCN5chloride channel 5 (ENSG00000171365), score: 0.64 CLDN16claudin 16 (ENSG00000113946), score: 0.84 CLDN19claudin 19 (ENSG00000164007), score: 0.9 CLIC6chloride intracellular channel 6 (ENSG00000159212), score: 0.83 CNNM2cyclin M2 (ENSG00000148842), score: 0.72 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.66 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.69 CRISP1cysteine-rich secretory protein 1 (ENSG00000124812), score: 0.57 CTDSPLCTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like (ENSG00000144677), score: 0.65 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.88 CYBASC3cytochrome b, ascorbate dependent 3 (ENSG00000162144), score: 0.48 CYTIPcytohesin 1 interacting protein (ENSG00000115165), score: 0.49 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.73 DAOD-amino-acid oxidase (ENSG00000110887), score: 0.63 DCUN1D5DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) (ENSG00000137692), score: -0.53 DDCdopa decarboxylase (aromatic L-amino acid decarboxylase) (ENSG00000132437), score: 0.49 DENND2DDENN/MADD domain containing 2D (ENSG00000162777), score: 0.56 DHDPSLdihydrodipicolinate synthase-like, mitochondrial (ENSG00000241935), score: 0.67 DMGDHdimethylglycine dehydrogenase (ENSG00000132837), score: 0.48 DNMBPdynamin binding protein (ENSG00000107554), score: 0.5 DPEP1dipeptidase 1 (renal) (ENSG00000015413), score: 0.69 DPP4dipeptidyl-peptidase 4 (ENSG00000197635), score: 0.68 DPYSdihydropyrimidinase (ENSG00000147647), score: 0.5 EGFepidermal growth factor (ENSG00000138798), score: 0.54 EHFets homologous factor (ENSG00000135373), score: 0.73 ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ENSG00000163435), score: 0.58 ELF5E74-like factor 5 (ets domain transcription factor) (ENSG00000135374), score: 0.87 ELMO3engulfment and cell motility 3 (ENSG00000102890), score: 0.5 ENPEPglutamyl aminopeptidase (aminopeptidase A) (ENSG00000138792), score: 0.53 EPCAMepithelial cell adhesion molecule (ENSG00000119888), score: 0.61 EREGepiregulin (ENSG00000124882), score: 0.55 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.72 EVCEllis van Creveld syndrome (ENSG00000072840), score: 0.58 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.71 FAM3Dfamily with sequence similarity 3, member D (ENSG00000198643), score: 0.7 FAM83Bfamily with sequence similarity 83, member B (ENSG00000168143), score: 0.55 FERMT1fermitin family member 1 (ENSG00000101311), score: 0.54 FOXI1forkhead box I1 (ENSG00000168269), score: 0.85 FRAS1Fraser syndrome 1 (ENSG00000138759), score: 0.75 FZD6frizzled homolog 6 (Drosophila) (ENSG00000164930), score: 0.5 GABRPgamma-aminobutyric acid (GABA) A receptor, pi (ENSG00000094755), score: 0.53 GALK2galactokinase 2 (ENSG00000156958), score: 0.53 GALNT11UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (ENSG00000178234), score: 0.48 GALNT14UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (ENSG00000158089), score: 0.72 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.84 GCM1glial cells missing homolog 1 (Drosophila) (ENSG00000137270), score: 0.68 GHRHRgrowth hormone releasing hormone receptor (ENSG00000106128), score: 0.48 GOPCgolgi-associated PDZ and coiled-coil motif containing (ENSG00000047932), score: -0.53 GRAMD2GRAM domain containing 2 (ENSG00000175318), score: 0.49 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.87 GRK5G protein-coupled receptor kinase 5 (ENSG00000198873), score: -0.47 GSCgoosecoid homeobox (ENSG00000133937), score: 0.91 HAO2hydroxyacid oxidase 2 (long chain) (ENSG00000116882), score: 0.5 HNF1AHNF1 homeobox A (ENSG00000135100), score: 0.51 HNF4Ahepatocyte nuclear factor 4, alpha (ENSG00000101076), score: 0.54 HNF4Ghepatocyte nuclear factor 4, gamma (ENSG00000164749), score: 0.7 HOXA10homeobox A10 (ENSG00000153807), score: 0.78 HOXB7homeobox B7 (ENSG00000120087), score: 0.77 HOXD10homeobox D10 (ENSG00000128710), score: 0.89 HOXD4homeobox D4 (ENSG00000170166), score: 0.85 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.83 IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (ENSG00000113302), score: 0.48 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.7 IRF6interferon regulatory factor 6 (ENSG00000117595), score: 0.51 IRX2iroquois homeobox 2 (ENSG00000170561), score: 0.54 ITGB4integrin, beta 4 (ENSG00000132470), score: 0.55 IVNS1ABPinfluenza virus NS1A binding protein (ENSG00000116679), score: 0.5 JAG1jagged 1 (ENSG00000101384), score: 0.59 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.77 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.7 KCNK5potassium channel, subfamily K, member 5 (ENSG00000164626), score: 0.55 KIAA1522KIAA1522 (ENSG00000162522), score: 0.54 KIF12kinesin family member 12 (ENSG00000136883), score: 0.53 KIRRELkin of IRRE like (Drosophila) (ENSG00000183853), score: 0.53 KLklotho (ENSG00000133116), score: 0.7 KLHDC7Akelch domain containing 7A (ENSG00000179023), score: 0.59 KLHL14kelch-like 14 (Drosophila) (ENSG00000197705), score: 0.69 LAD1ladinin 1 (ENSG00000159166), score: 0.66 LAMA1laminin, alpha 1 (ENSG00000101680), score: 0.58 LAMC3laminin, gamma 3 (ENSG00000050555), score: 0.61 LGALS2lectin, galactoside-binding, soluble, 2 (ENSG00000100079), score: 0.74 LGMNlegumain (ENSG00000100600), score: 0.74 LLGL2lethal giant larvae homolog 2 (Drosophila) (ENSG00000073350), score: 0.56 LMX1BLIM homeobox transcription factor 1, beta (ENSG00000136944), score: 0.67 LOC100290519similar to transcription factor MEL1 (ENSG00000142611), score: 0.53 LRRC58leucine rich repeat containing 58 (ENSG00000163428), score: 0.5 MARVELD2MARVEL domain containing 2 (ENSG00000152939), score: 0.51 MARVELD3MARVEL domain containing 3 (ENSG00000140832), score: 0.69 MPZL2myelin protein zero-like 2 (ENSG00000149573), score: 0.54 MYO19myosin XIX (ENSG00000141140), score: 0.5 MYO1Dmyosin ID (ENSG00000176658), score: 0.51 NEK8NIMA (never in mitosis gene a)- related kinase 8 (ENSG00000160602), score: 0.49 NHSNance-Horan syndrome (congenital cataracts and dental anomalies) (ENSG00000188158), score: 0.54 NMT2N-myristoyltransferase 2 (ENSG00000152465), score: -0.46 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.66 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 0.75 NPNTnephronectin (ENSG00000168743), score: 0.55 NPR3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (ENSG00000113389), score: 0.63 NTN4netrin 4 (ENSG00000074527), score: 0.49 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.64 OSTalphaorganic solute transporter alpha (ENSG00000163959), score: 0.49 PAQR5progestin and adipoQ receptor family member V (ENSG00000137819), score: 0.73 PCK1phosphoenolpyruvate carboxykinase 1 (soluble) (ENSG00000124253), score: 0.53 PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial) (ENSG00000100889), score: 0.53 PDCD5programmed cell death 5 (ENSG00000105185), score: -0.56 PEPDpeptidase D (ENSG00000124299), score: 0.61 PGPEP1pyroglutamyl-peptidase I (ENSG00000130517), score: 0.57 PHACTR4phosphatase and actin regulator 4 (ENSG00000204138), score: 0.48 PKD2polycystic kidney disease 2 (autosomal dominant) (ENSG00000118762), score: 0.49 PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific) (ENSG00000197943), score: 0.52 PLS1plastin 1 (ENSG00000120756), score: 0.56 PRLRprolactin receptor (ENSG00000113494), score: 0.51 PROM2prominin 2 (ENSG00000155066), score: 0.54 PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 (ENSG00000115233), score: -0.48 PTERphosphotriesterase related (ENSG00000165983), score: 0.53 PTGER4prostaglandin E receptor 4 (subtype EP4) (ENSG00000171522), score: 0.55 PTPRQprotein tyrosine phosphatase, receptor type, Q (ENSG00000139304), score: 0.71 PYROXD2pyridine nucleotide-disulphide oxidoreductase domain 2 (ENSG00000119943), score: 0.75 RAB19RAB19, member RAS oncogene family (ENSG00000146955), score: 0.88 RAB7L1RAB7, member RAS oncogene family-like 1 (ENSG00000117280), score: 0.57 RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (ENSG00000128340), score: 0.48 RASA3RAS p21 protein activator 3 (ENSG00000185989), score: -0.5 RASSF6Ras association (RalGDS/AF-6) domain family member 6 (ENSG00000169435), score: 0.54 RB1CC1RB1-inducible coiled-coil 1 (ENSG00000023287), score: -0.47 RBKSribokinase (ENSG00000171174), score: 0.48 REEP1receptor accessory protein 1 (ENSG00000068615), score: -0.49 RHAGRh-associated glycoprotein (ENSG00000112077), score: 0.69 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.8 RIPK4receptor-interacting serine-threonine kinase 4 (ENSG00000183421), score: 0.48 RXFP3relaxin/insulin-like family peptide receptor 3 (ENSG00000182631), score: 0.56 SACSspastic ataxia of Charlevoix-Saguenay (sacsin) (ENSG00000151835), score: -0.48 SALL1sal-like 1 (Drosophila) (ENSG00000103449), score: 0.55 SCAMP2secretory carrier membrane protein 2 (ENSG00000140497), score: 0.51 SCINscinderin (ENSG00000006747), score: 0.7 SCNN1Asodium channel, nonvoltage-gated 1 alpha (ENSG00000111319), score: 0.71 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.87 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.79 SDSLserine dehydratase-like (ENSG00000139410), score: 0.58 SEMA3Fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (ENSG00000001617), score: 0.5 SFXN2sideroflexin 2 (ENSG00000156398), score: 0.63 SGK1serum/glucocorticoid regulated kinase 1 (ENSG00000118515), score: 0.5 SGK2serum/glucocorticoid regulated kinase 2 (ENSG00000101049), score: 0.5 SHISA2shisa homolog 2 (Xenopus laevis) (ENSG00000180730), score: 0.65 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 1 SIM2single-minded homolog 2 (Drosophila) (ENSG00000159263), score: 0.52 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.76 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.7 SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (ENSG00000158296), score: 0.67 SLC16A12solute carrier family 16, member 12 (monocarboxylic acid transporter 12) (ENSG00000152779), score: 0.66 SLC16A2solute carrier family 16, member 2 (monocarboxylic acid transporter 8) (ENSG00000147100), score: 0.53 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.85 SLC22A4solute carrier family 22 (organic cation/ergothioneine transporter), member 4 (ENSG00000197208), score: 0.61 SLC22A7solute carrier family 22 (organic anion transporter), member 7 (ENSG00000137204), score: 0.52 SLC25A10solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 (ENSG00000183048), score: 0.52 SLC25A48solute carrier family 25, member 48 (ENSG00000145832), score: 0.7 SLC26A7solute carrier family 26, member 7 (ENSG00000147606), score: 0.54 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.86 SLC35F2solute carrier family 35, member F2 (ENSG00000110660), score: 0.58 SLC3A1solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 (ENSG00000138079), score: 0.55 SLC44A3solute carrier family 44, member 3 (ENSG00000143036), score: 0.51 SLC4A4solute carrier family 4, sodium bicarbonate cotransporter, member 4 (ENSG00000080493), score: 0.49 SLC5A11solute carrier family 5 (sodium/glucose cotransporter), member 11 (ENSG00000158865), score: 0.59 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.8 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 0.68 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.94 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.64 SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 3 (ENSG00000066230), score: 0.49 SMYD2SET and MYND domain containing 2 (ENSG00000143499), score: -0.48 SRMSsrc-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites (ENSG00000125508), score: 0.7 ST14suppression of tumorigenicity 14 (colon carcinoma) (ENSG00000149418), score: 0.65 STC1stanniocalcin 1 (ENSG00000159167), score: 0.53 SULF2sulfatase 2 (ENSG00000196562), score: 0.5 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.8 SUSD3sushi domain containing 3 (ENSG00000157303), score: 0.57 SYDE2synapse defective 1, Rho GTPase, homolog 2 (C. elegans) (ENSG00000097096), score: 0.51 TBC1D22BTBC1 domain family, member 22B (ENSG00000065491), score: 0.49 TBX2T-box 2 (ENSG00000121068), score: 0.48 TCN2transcobalamin II (ENSG00000185339), score: 0.59 TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (ENSG00000137203), score: 0.59 TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta) (ENSG00000008196), score: 0.69 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.77 THNSL2threonine synthase-like 2 (S. cerevisiae) (ENSG00000144115), score: 0.5 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.75 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.76 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.75 TMEM51transmembrane protein 51 (ENSG00000171729), score: 0.56 TMIGD1transmembrane and immunoglobulin domain containing 1 (ENSG00000182271), score: 0.85 TMPRSS13transmembrane protease, serine 13 (ENSG00000137747), score: 0.96 TMPRSS2transmembrane protease, serine 2 (ENSG00000184012), score: 0.67 TNFSF15tumor necrosis factor (ligand) superfamily, member 15 (ENSG00000181634), score: 0.74 TPP1tripeptidyl peptidase I (ENSG00000166340), score: 0.59 TRPM6transient receptor potential cation channel, subfamily M, member 6 (ENSG00000119121), score: 0.79 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.53 UBLCP1ubiquitin-like domain containing CTD phosphatase 1 (ENSG00000164332), score: -0.49 UPB1ureidopropionase, beta (ENSG00000100024), score: 0.53 UPK3Auroplakin 3A (ENSG00000100373), score: 0.55 WDR41WD repeat domain 41 (ENSG00000164253), score: -0.47 WDR72WD repeat domain 72 (ENSG00000166415), score: 0.53 WNK1WNK lysine deficient protein kinase 1 (ENSG00000060237), score: 0.65 XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (ENSG00000122121), score: 0.85 ZEB1zinc finger E-box binding homeobox 1 (ENSG00000148516), score: -0.53 ZNF704zinc finger protein 704 (ENSG00000164684), score: 0.49 ZPLD1zona pellucida-like domain containing 1 (ENSG00000170044), score: 0.52

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
mml_kd_m_ca1	mml	kd	m	_
hsa_kd_m1_ca1	hsa	kd	m	1
mml_kd_f_ca1	mml	kd	f	_
oan_kd_f_ca1	oan	kd	f	_
gga_kd_f_ca1	gga	kd	f	_
gga_kd_m_ca1	gga	kd	m	_
mdo_kd_m_ca1	mdo	kd	m	_
mdo_kd_f_ca1	mdo	kd	f	_