Under-expression is coded with green,
over-expression with red color.
cell morphogenesis
The developmental process by which the size or shape of a cell is generated and organized. Morphogenesis pertains to the creation of form.
cell morphogenesis involved in differentiation
The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
startle response
An action or movement due to the application of a sudden unexpected stimulus.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
vesicle-mediated transport
The directed movement of substances into, out of or within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane. Vesicles are then targeted to, and fuse with, an acceptor membrane.
secretion
The controlled release of a substance by a cell, a group of cells, or a tissue.
cell adhesion
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
transport
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.
ion transport
The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.
cation transport
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.
potassium ion transport
The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.
calcium ion transport
The directed movement of calcium (Ca) ions into, out of, within or between cells by means of some external agent such as a transporter or pore.
metal ion transport
The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.
neurotransmitter transport
The directed movement of a neurotransmitter into, out of, within or between cells by means of some external agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
exocytosis
A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells.
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
homophilic cell adhesion
The attachment of an adhesion molecule in one cell to an identical molecule in an adjacent cell.
cell surface receptor linked signaling pathway
Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.
G-protein coupled receptor protein signaling pathway
The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.
glutamate signaling pathway
The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor.
cell-cell signaling
Any process that mediates the transfer of information from one cell to another.
synaptic transmission
The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
anatomical structure morphogenesis
The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
nervous system development
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
neurological system process
A organ system process carried out by any of the organs or tissues of neurological system.
axonogenesis
Generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells.
behavior
The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
learning or memory
The acquisition and processing of information and/or the storage and retrieval of this information over time.
learning
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
memory
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
cell recognition
The process by which a cell in a multicellular organism interprets its surroundings.
neuron recognition
The process by which a neuronal cell in a multicellular organism interprets its surroundings.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
associative learning
Learning by associating a stimulus (the cause) with a particular outcome (the effect).
response to external stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of cell communication
Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
regulation of cell morphogenesis involved in differentiation
Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
regulation of neuron projection development
Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
monovalent inorganic cation transport
The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
di-, tri-valent inorganic cation transport
The directed movement of inorganic cations with a valency of two or three into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
cellular component organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
cell-cell adhesion
The attachment of one cell to another cell via adhesion molecules.
regulation of exocytosis
Any process that modulates the frequency, rate or extent of exocytosis.
transmission of nerve impulse
The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.
neurogenesis
Generation of cells within the nervous system.
regulation of anatomical structure morphogenesis
Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.
regulation of cell morphogenesis
Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process by which the shape of a cell is generated and organized.
biological adhesion
The attachment of a cell or organism to a substrate or other organism.
signaling pathway
The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms.
signaling process
Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.
signaling
The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.
signal transmission
The process whereby a signal is released and/or conveyed from one location to another.
cell projection organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
cell differentiation
The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
neuron differentiation
The process whereby a relatively unspecialized cell acquires specialized features of a neuron.
neuron projection development
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
regulation of cell projection organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
regulation of neurological system process
Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
regulation of localization
Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
secretion by cell
The controlled release of a substance by a cell.
cellular component morphogenesis
The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.
cell part morphogenesis
The process by which the anatomical structures of a cell part are generated and organized. Morphogenesis pertains to the creation of form.
ionotropic glutamate receptor signaling pathway
The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor, followed by the movement of ions through a channel in the receptor complex.
regulation of system process
Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.
regulation of cell differentiation
Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.
regulation of neuron differentiation
Any process that modulates the frequency, rate or extent of neuron differentiation.
regulation of synaptic plasticity
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
regulation of neuronal synaptic plasticity
A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
cell development
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
neuron development
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
cell morphogenesis involved in neuron differentiation
The process by which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.
generation of neurons
The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
neuron projection morphogenesis
The process by which the anatomical structures of a neuron projection are generated and organized. Morphogenesis pertains to the creation of form. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
cell projection morphogenesis
The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
regulation of neurogenesis
Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
regulation of axonogenesis
Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of developmental process
Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of synaptic transmission
Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
cognition
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
neuromuscular process
Any process pertaining to the functions of the nervous and muscular systems of an organism.
regulation of secretion
Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or group of cells.
regulation of transport
Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.
regulation of cellular component organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
localization
Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
cellular localization
Any process by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.
establishment of localization in cell
The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell.
regulation of nervous system development
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
regulation of transmission of nerve impulse
Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
transmembrane transport
The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.
regulation of cell development
Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
regulation of cellular localization
Any process that modulates the frequency, rate or extent of a process by which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.
regulation of vesicle-mediated transport
Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
regulation of biological quality
Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
divalent metal ion transport
The directed movement of divalent metal cations, any metal ion with a +2 electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.
regulation of multicellular organismal development
Any process that modulates the frequency, rate or extent of multicellular organismal development.
all
NA
cell projection organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
cell adhesion
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
signaling process
Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.
cell recognition
The process by which a cell in a multicellular organism interprets its surroundings.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
regulation of developmental process
Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of cellular component organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
regulation of localization
Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
cellular localization
Any process by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
cell-cell signaling
Any process that mediates the transfer of information from one cell to another.
exocytosis
A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells.
cellular component morphogenesis
The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.
regulation of cell communication
Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
regulation of cell projection organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
regulation of vesicle-mediated transport
Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
establishment of localization in cell
The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell.
regulation of cellular localization
Any process that modulates the frequency, rate or extent of a process by which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.
regulation of cell morphogenesis
Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process by which the shape of a cell is generated and organized.
regulation of cell projection organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
transmission of nerve impulse
The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.
regulation of system process
Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.
regulation of multicellular organismal development
Any process that modulates the frequency, rate or extent of multicellular organismal development.
cellular component morphogenesis
The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.
anatomical structure morphogenesis
The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
cell development
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
regulation of anatomical structure morphogenesis
Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.
regulation of cell differentiation
Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.
regulation of multicellular organismal development
Any process that modulates the frequency, rate or extent of multicellular organismal development.
regulation of cellular localization
Any process that modulates the frequency, rate or extent of a process by which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.
vesicle-mediated transport
The directed movement of substances into, out of or within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane. Vesicles are then targeted to, and fuse with, an acceptor membrane.
regulation of transport
Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.
transmembrane transport
The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.
secretion by cell
The controlled release of a substance by a cell.
regulation of exocytosis
Any process that modulates the frequency, rate or extent of exocytosis.
synaptic transmission
The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
regulation of transmission of nerve impulse
Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
regulation of neuron projection development
Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
neuron projection morphogenesis
The process by which the anatomical structures of a neuron projection are generated and organized. Morphogenesis pertains to the creation of form. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
regulation of cell differentiation
Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.
cell development
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
regulation of cell development
Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
regulation of exocytosis
Any process that modulates the frequency, rate or extent of exocytosis.
cell morphogenesis involved in differentiation
The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
regulation of cell morphogenesis
Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process by which the shape of a cell is generated and organized.
cell projection morphogenesis
The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.
cell projection morphogenesis
The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.
transmission of nerve impulse
The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.
regulation of neurological system process
Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.
regulation of cell morphogenesis
Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process by which the shape of a cell is generated and organized.
regulation of vesicle-mediated transport
Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
secretion by cell
The controlled release of a substance by a cell.
regulation of secretion
Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or group of cells.
regulation of synaptic transmission
Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
neuron development
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
regulation of cell morphogenesis involved in differentiation
Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
neuron recognition
The process by which a neuronal cell in a multicellular organism interprets its surroundings.
neuron projection development
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
cell morphogenesis involved in neuron differentiation
The process by which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.
regulation of cell morphogenesis involved in differentiation
Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
regulation of neurogenesis
Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
regulation of axonogenesis
Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
regulation of synaptic plasticity
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
regulation of transmission of nerve impulse
Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
learning or memory
The acquisition and processing of information and/or the storage and retrieval of this information over time.
startle response
An action or movement due to the application of a sudden unexpected stimulus.
neurogenesis
Generation of cells within the nervous system.
regulation of nervous system development
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
regulation of neurogenesis
Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
regulation of exocytosis
Any process that modulates the frequency, rate or extent of exocytosis.
regulation of axonogenesis
Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
neuron differentiation
The process whereby a relatively unspecialized cell acquires specialized features of a neuron.
regulation of neurogenesis
Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
regulation of neuron differentiation
Any process that modulates the frequency, rate or extent of neuron differentiation.
regulation of neuron projection development
Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
axonogenesis
Generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells.
potassium ion transport
The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.
divalent metal ion transport
The directed movement of divalent metal cations, any metal ion with a +2 electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endocytic vesicle
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance.
cytoskeleton
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
synaptic vesicle
A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
ionotropic glutamate receptor complex
A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.
endomembrane system
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
vesicle membrane
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
postsynaptic density
The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.
cytoplasmic membrane-bounded vesicle
A membrane-bounded vesicle found in the cytoplasm of the cell.
N-methyl-D-aspartate selective glutamate receptor complex
An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD.
cell junction
A plasma membrane part that forms a specialized region of connection between two cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
coated vesicle
Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.
clathrin-coated vesicle
A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
outer membrane-bounded periplasmic space
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin cell wall.
external encapsulating structure
A structure that lies outside the plasma membrane and surrounds the entire cell.
cell envelope
An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present.
axon
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
dendrite
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
cytoplasmic vesicle membrane
The lipid bilayer surrounding a cytoplasmic vesicle.
coated vesicle membrane
The lipid bilayer surrounding a coated vesicle.
clathrin coated vesicle membrane
The lipid bilayer surrounding a clathrin-coated vesicle.
endocytic vesicle membrane
The lipid bilayer surrounding an endocytic vesicle.
synaptic vesicle membrane
The lipid bilayer surrounding a synaptic vesicle.
organelle membrane
The lipid bilayer surrounding an organelle.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
cytoplasmic vesicle
A vesicle formed of membrane or protein, found in the cytoplasm of a cell.
envelope
A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.
vesicle
Any small, fluid-filled, spherical organelle enclosed by membrane or protein.
membrane-bounded vesicle
Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
axon part
A part of an axon, a cell projection of a neuron.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
cation channel complex
An ion channel complex through which cations pass.
potassium channel complex
An ion channel complex through which potassium ions pass.
chloride channel complex
An ion channel complex through which chloride ions pass.
periplasmic space
The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or inner membrane and cell wall (Fungi).
presynaptic membrane
A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
cell projection
A prolongation or process extending from a cell, e.g. a flagellum or axon.
neuron projection
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
dendritic spine
Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
receptor complex
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
axon terminus
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
neuron projection terminus
The specialized, terminal region of a neuron projection such as an axon or a dendrite.
neuron spine
A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
cytoskeletal part
Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.
cytoplasmic vesicle part
Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
synapse part
Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
external encapsulating structure part
Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell.
cell projection part
Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
synapse
The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
postsynaptic membrane
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.
all
NA
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
synapse part
Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
organelle membrane
The lipid bilayer surrounding an organelle.
cytoplasmic vesicle
A vesicle formed of membrane or protein, found in the cytoplasm of a cell.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
organelle membrane
The lipid bilayer surrounding an organelle.
presynaptic membrane
A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
postsynaptic membrane
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.
vesicle membrane
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
external encapsulating structure part
Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell.
cell projection part
Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
outer membrane-bounded periplasmic space
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin cell wall.
cytoplasmic vesicle part
Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.
vesicle membrane
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
cytoplasmic membrane-bounded vesicle
A membrane-bounded vesicle found in the cytoplasm of the cell.
cytoplasmic membrane-bounded vesicle
A membrane-bounded vesicle found in the cytoplasm of the cell.
postsynaptic density
The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.
cytoplasmic vesicle membrane
The lipid bilayer surrounding a cytoplasmic vesicle.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
outer membrane-bounded periplasmic space
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin cell wall.
neuron projection terminus
The specialized, terminal region of a neuron projection such as an axon or a dendrite.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoplasmic vesicle
A vesicle formed of membrane or protein, found in the cytoplasm of a cell.
cytoplasmic vesicle part
Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.
ionotropic glutamate receptor complex
A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
axon terminus
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
cytoplasmic vesicle membrane
The lipid bilayer surrounding a cytoplasmic vesicle.
cytoskeletal part
Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.
axon part
A part of an axon, a cell projection of a neuron.
dendritic spine
Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.
dendritic spine
Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
endocytic vesicle membrane
The lipid bilayer surrounding an endocytic vesicle.
coated vesicle membrane
The lipid bilayer surrounding a coated vesicle.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
ionotropic glutamate receptor complex
A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.
synaptic vesicle
A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
clathrin coated vesicle membrane
The lipid bilayer surrounding a clathrin-coated vesicle.
synaptic vesicle membrane
The lipid bilayer surrounding a synaptic vesicle.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
signal transducer activity
Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.
receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
transmembrane receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.
G-protein coupled receptor activity
A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.
ionotropic glutamate receptor activity
Combining with glutamate to initiate a change in cell activity through the regulation of ion channels.
N-methyl-D-aspartate selective glutamate receptor activity
NA
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
ion channel activity
Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
extracellular ligand-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.
excitatory extracellular ligand-gated ion channel activity
NA
extracellular-glutamate-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
voltage-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.
voltage-gated potassium channel activity
Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.
cation channel activity
Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
calcium channel activity
Catalysis of facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
potassium channel activity
Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
transmembrane transporter activity
Enables the transfer of a substance from one side of a membrane to the other.
binding
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
glutamate receptor activity
Combining with glutamate to initiate a change in cell activity.
cation transmembrane transporter activity
Catalysis of the transfer of cation from one side of the membrane to the other.
glycine binding
Interacting selectively and non-covalently with glycine, aminoethanoic acid.
ion transmembrane transporter activity
Catalysis of the transfer of an ion from one side of a membrane to the other.
channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
ligand-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
amino acid binding
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
passive transmembrane transporter activity
Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.
voltage-gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
ligand-gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.
substrate-specific channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
voltage-gated cation channel activity
Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific transporter activity
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
carboxylic acid binding
Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
neurotransmitter binding
Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
amine binding
Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group.
molecular transducer activity
The molecular function that accepts an input of one form and creates an output of a different form.
all
NA
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
amino acid binding
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
substrate-specific channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
ion channel activity
Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
cation channel activity
Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
voltage-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.
ligand-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
voltage-gated cation channel activity
Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.
voltage-gated potassium channel activity
Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.
Id | Pvalue | ExpCount | Count | Size | Term |
---|---|---|---|---|---|
04080 | 4.423e-09 | 4.922 | 24 | 102 | Neuroactive ligand-receptor interaction |
04720 | 1.470e-06 | 1.206 | 11 | 25 | Long-term potentiation |
04020 | 5.172e-05 | 3.281 | 15 | 68 | Calcium signaling pathway |
05014 | 2.335e-04 | 0.965 | 8 | 20 | Amyotrophic lateral sclerosis (ALS) |
04730 | 6.432e-04 | 1.448 | 9 | 30 | Long-term depression |
04970 | 2.651e-03 | 1.013 | 7 | 21 | Salivary secretion |
04971 | 3.846e-03 | 1.448 | 8 | 30 | Gastric acid secretion |
04540 | 2.982e-02 | 1.592 | 7 | 33 | Gap junction |
ADCY2adenylate cyclase 2 (brain) (ENSG00000078295), score: 0.75 AK2adenylate kinase 2 (ENSG00000004455), score: -0.63 ANO3anoctamin 3 (ENSG00000134343), score: 0.9 ARCactivity-regulated cytoskeleton-associated protein (ENSG00000198576), score: 0.8 ARHGAP32Rho GTPase activating protein 32 (ENSG00000134909), score: 0.81 ARPP21cAMP-regulated phosphoprotein, 21kDa (ENSG00000172995), score: 0.71 ASTN1astrotactin 1 (ENSG00000152092), score: 0.75 ATL1atlastin GTPase 1 (ENSG00000198513), score: 0.7 ATP2B1ATPase, Ca++ transporting, plasma membrane 1 (ENSG00000070961), score: 0.8 ATP6V1B2ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 (ENSG00000147416), score: 0.71 ATRNL1attractin-like 1 (ENSG00000107518), score: 0.79 B3GALT1UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 (ENSG00000172318), score: 0.71 B4GALT1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (ENSG00000086062), score: -0.68 BAI1brain-specific angiogenesis inhibitor 1 (ENSG00000181790), score: 0.79 BCL11BB-cell CLL/lymphoma 11B (zinc finger protein) (ENSG00000127152), score: 0.95 C11orf41chromosome 11 open reading frame 41 (ENSG00000110427), score: 0.74 C13orf36chromosome 13 open reading frame 36 (ENSG00000180440), score: 0.91 C20orf103chromosome 20 open reading frame 103 (ENSG00000125869), score: 0.77 C6orf168chromosome 6 open reading frame 168 (ENSG00000146267), score: 0.71 C8orf34chromosome 8 open reading frame 34 (ENSG00000165084), score: 0.77 C8orf46chromosome 8 open reading frame 46 (ENSG00000169085), score: 0.75 CACNA1Ecalcium channel, voltage-dependent, R type, alpha 1E subunit (ENSG00000198216), score: 0.83 CACNG3calcium channel, voltage-dependent, gamma subunit 3 (ENSG00000006116), score: 0.88 CACNG4calcium channel, voltage-dependent, gamma subunit 4 (ENSG00000075461), score: 0.73 CADM2cell adhesion molecule 2 (ENSG00000175161), score: 0.75 CAMK1Gcalcium/calmodulin-dependent protein kinase IG (ENSG00000008118), score: 0.78 CAMK2Acalcium/calmodulin-dependent protein kinase II alpha (ENSG00000070808), score: 0.86 CBLN4cerebellin 4 precursor (ENSG00000054803), score: 0.93 CDH10cadherin 10, type 2 (T2-cadherin) (ENSG00000040731), score: 0.79 CDH12cadherin 12, type 2 (N-cadherin 2) (ENSG00000154162), score: 0.81 CDH4cadherin 4, type 1, R-cadherin (retinal) (ENSG00000179242), score: 0.77 CDH9cadherin 9, type 2 (T1-cadherin) (ENSG00000113100), score: 0.91 CDKL5cyclin-dependent kinase-like 5 (ENSG00000008086), score: 0.74 CELF2CUGBP, Elav-like family member 2 (ENSG00000048740), score: 0.72 CELF5CUGBP, Elav-like family member 5 (ENSG00000161082), score: 0.72 CHN1chimerin (chimaerin) 1 (ENSG00000128656), score: 0.76 CHRM3cholinergic receptor, muscarinic 3 (ENSG00000133019), score: 0.95 CHST1carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 (ENSG00000175264), score: 0.79 CLSTN2calsyntenin 2 (ENSG00000158258), score: 0.7 CLTCclathrin, heavy chain (Hc) (ENSG00000141367), score: 0.72 CNIH3cornichon homolog 3 (Drosophila) (ENSG00000143786), score: 0.8 CNKSR2connector enhancer of kinase suppressor of Ras 2 (ENSG00000149970), score: 0.72 CNTN3contactin 3 (plasmacytoma associated) (ENSG00000113805), score: 0.91 CPNE4copine IV (ENSG00000196353), score: 0.82 CRHcorticotropin releasing hormone (ENSG00000147571), score: 0.82 CSMD2CUB and Sushi multiple domains 2 (ENSG00000121904), score: 0.73 CSRNP3cysteine-serine-rich nuclear protein 3 (ENSG00000178662), score: 0.78 DBC1deleted in bladder cancer 1 (ENSG00000078725), score: 0.71 DCLK1doublecortin-like kinase 1 (ENSG00000133083), score: 0.81 DGKIdiacylglycerol kinase, iota (ENSG00000157680), score: 0.8 DLGAP2discs, large (Drosophila) homolog-associated protein 2 (ENSG00000198010), score: 0.91 DLX1distal-less homeobox 1 (ENSG00000144355), score: 0.96 DLX6distal-less homeobox 6 (ENSG00000006377), score: 0.8 DNMBPdynamin binding protein (ENSG00000107554), score: -0.63 DOCK3dedicator of cytokinesis 3 (ENSG00000088538), score: 0.73 DOCK4dedicator of cytokinesis 4 (ENSG00000128512), score: 0.72 DRP2dystrophin related protein 2 (ENSG00000102385), score: 0.82 DSCAMDown syndrome cell adhesion molecule (ENSG00000171587), score: 0.86 DSCAML1Down syndrome cell adhesion molecule like 1 (ENSG00000177103), score: 0.72 ELFN2extracellular leucine-rich repeat and fibronectin type III domain containing 2 (ENSG00000166897), score: 0.81 ELMOD1ELMO/CED-12 domain containing 1 (ENSG00000110675), score: 0.71 ENC1ectodermal-neural cortex 1 (with BTB-like domain) (ENSG00000171617), score: 0.88 EPHA5EPH receptor A5 (ENSG00000145242), score: 0.88 EPHX4epoxide hydrolase 4 (ENSG00000172031), score: 0.83 FAM171Bfamily with sequence similarity 171, member B (ENSG00000144369), score: 0.73 FAM19A1family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 (ENSG00000183662), score: 0.98 FAM49Afamily with sequence similarity 49, member A (ENSG00000197872), score: 0.81 FAM5Bfamily with sequence similarity 5, member B (ENSG00000198797), score: 0.83 FAM5Cfamily with sequence similarity 5, member C (ENSG00000162670), score: 0.8 FAM81Afamily with sequence similarity 81, member A (ENSG00000157470), score: 0.78 FBXL16F-box and leucine-rich repeat protein 16 (ENSG00000127585), score: 0.7 FEZF2FEZ family zinc finger 2 (ENSG00000153266), score: 0.9 FIBCD1fibrinogen C domain containing 1 (ENSG00000130720), score: 0.78 FLRT2fibronectin leucine rich transmembrane protein 2 (ENSG00000185070), score: 0.82 FOXG1forkhead box G1 (ENSG00000176165), score: 0.84 FRMPD4FERM and PDZ domain containing 4 (ENSG00000169933), score: 0.81 GABRA1gamma-aminobutyric acid (GABA) A receptor, alpha 1 (ENSG00000022355), score: 0.72 GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 2 (ENSG00000151834), score: 0.79 GABRB3gamma-aminobutyric acid (GABA) A receptor, beta 3 (ENSG00000166206), score: 0.75 GABRG2gamma-aminobutyric acid (GABA) A receptor, gamma 2 (ENSG00000113327), score: 0.73 GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (ENSG00000136750), score: 0.78 GALNTL6UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6 (ENSG00000174473), score: 0.72 GLRA3glycine receptor, alpha 3 (ENSG00000145451), score: 1 GLRBglycine receptor, beta (ENSG00000109738), score: 0.72 GPR123G protein-coupled receptor 123 (ENSG00000197177), score: 0.82 GPR83G protein-coupled receptor 83 (ENSG00000123901), score: 0.75 GRIA1glutamate receptor, ionotropic, AMPA 1 (ENSG00000155511), score: 0.74 GRIA2glutamate receptor, ionotropic, AMPA 2 (ENSG00000120251), score: 0.75 GRIA3glutamate receptor, ionotrophic, AMPA 3 (ENSG00000125675), score: 0.81 GRIK3glutamate receptor, ionotropic, kainate 3 (ENSG00000163873), score: 0.72 GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 (ENSG00000176884), score: 0.72 GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A (ENSG00000183454), score: 0.77 GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B (ENSG00000150086), score: 0.88 GRIN3Aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A (ENSG00000198785), score: 0.75 GRM3glutamate receptor, metabotropic 3 (ENSG00000198822), score: 0.76 HBP1HMG-box transcription factor 1 (ENSG00000105856), score: -0.63 HCN1hyperpolarization activated cyclic nucleotide-gated potassium channel 1 (ENSG00000164588), score: 0.72 HMP19HMP19 protein (ENSG00000170091), score: 0.75 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (ENSG00000102468), score: 0.89 HTR45-hydroxytryptamine (serotonin) receptor 4 (ENSG00000164270), score: 0.96 IL1RAPL1interleukin 1 receptor accessory protein-like 1 (ENSG00000169306), score: 0.78 ITPKAinositol 1,4,5-trisphosphate 3-kinase A (ENSG00000137825), score: 0.7 KCNA3potassium voltage-gated channel, shaker-related subfamily, member 3 (ENSG00000177272), score: 0.77 KCNA4potassium voltage-gated channel, shaker-related subfamily, member 4 (ENSG00000182255), score: 0.87 KCNA6potassium voltage-gated channel, shaker-related subfamily, member 6 (ENSG00000151079), score: 0.84 KCNF1potassium voltage-gated channel, subfamily F, member 1 (ENSG00000162975), score: 0.89 KCNG1potassium voltage-gated channel, subfamily G, member 1 (ENSG00000026559), score: 0.74 KCNG3potassium voltage-gated channel, subfamily G, member 3 (ENSG00000171126), score: 0.85 KCNH7potassium voltage-gated channel, subfamily H (eag-related), member 7 (ENSG00000184611), score: 0.83 KCNK2potassium channel, subfamily K, member 2 (ENSG00000082482), score: 0.94 KCNQ3potassium voltage-gated channel, KQT-like subfamily, member 3 (ENSG00000184156), score: 0.86 KCNQ5potassium voltage-gated channel, KQT-like subfamily, member 5 (ENSG00000185760), score: 0.95 KCNS1potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 (ENSG00000124134), score: 0.94 KCNS2potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 (ENSG00000156486), score: 0.99 KCTD16potassium channel tetramerisation domain containing 16 (ENSG00000183775), score: 0.85 KCTD4potassium channel tetramerisation domain containing 4 (ENSG00000180332), score: 0.91 KIAA2022KIAA2022 (ENSG00000050030), score: 0.72 KLHL2kelch-like 2, Mayven (Drosophila) (ENSG00000109466), score: 0.71 LINGO2leucine rich repeat and Ig domain containing 2 (ENSG00000174482), score: 0.84 LMO4LIM domain only 4 (ENSG00000143013), score: 0.78 LMTK2lemur tyrosine kinase 2 (ENSG00000164715), score: 0.77 LPCAT3lysophosphatidylcholine acyltransferase 3 (ENSG00000111684), score: -0.67 LPPR3lipid phosphate phosphatase-related protein type 3 (ENSG00000129951), score: 0.8 LPPR4lipid phosphate phosphatase-related protein type 4 (ENSG00000117600), score: 0.9 LRFN2leucine rich repeat and fibronectin type III domain containing 2 (ENSG00000156564), score: 0.86 LRFN5leucine rich repeat and fibronectin type III domain containing 5 (ENSG00000165379), score: 0.81 LRRC4Cleucine rich repeat containing 4C (ENSG00000148948), score: 0.82 LRRC7leucine rich repeat containing 7 (ENSG00000033122), score: 0.93 LRRTM3leucine rich repeat transmembrane neuronal 3 (ENSG00000198739), score: 0.76 LRTM2leucine-rich repeats and transmembrane domains 2 (ENSG00000166159), score: 0.8 MAP2K1mitogen-activated protein kinase kinase 1 (ENSG00000169032), score: 0.75 MATKmegakaryocyte-associated tyrosine kinase (ENSG00000007264), score: 0.71 MC4Rmelanocortin 4 receptor (ENSG00000166603), score: 0.81 MEF2Cmyocyte enhancer factor 2C (ENSG00000081189), score: 0.86 MGAT5Bmannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B (ENSG00000167889), score: 0.77 MKL2MKL/myocardin-like 2 (ENSG00000186260), score: 0.94 MMP16matrix metallopeptidase 16 (membrane-inserted) (ENSG00000156103), score: 0.72 MTFR1mitochondrial fission regulator 1 (ENSG00000066855), score: -0.65 MYO1Cmyosin IC (ENSG00000197879), score: -0.65 MYO5Amyosin VA (heavy chain 12, myoxin) (ENSG00000197535), score: 0.7 MYT1Lmyelin transcription factor 1-like (ENSG00000186487), score: 0.73 NALCNsodium leak channel, non-selective (ENSG00000102452), score: 0.72 NCS1neuronal calcium sensor 1 (ENSG00000107130), score: 0.71 NECAB1N-terminal EF-hand calcium binding protein 1 (ENSG00000123119), score: 0.82 NEFLneurofilament, light polypeptide (ENSG00000104725), score: 0.7 NELL2NEL-like 2 (chicken) (ENSG00000184613), score: 0.74 NETO1neuropilin (NRP) and tolloid (TLL)-like 1 (ENSG00000166342), score: 1 NGEFneuronal guanine nucleotide exchange factor (ENSG00000066248), score: 0.76 NLGN1neuroligin 1 (ENSG00000169760), score: 0.75 NOVnephroblastoma overexpressed gene (ENSG00000136999), score: 0.77 NPEPL1aminopeptidase-like 1 (ENSG00000215440), score: -0.64 NPTNneuroplastin (ENSG00000156642), score: 0.74 NPY2Rneuropeptide Y receptor Y2 (ENSG00000185149), score: 0.92 NRCAMneuronal cell adhesion molecule (ENSG00000091129), score: 0.71 NRSN1neurensin 1 (ENSG00000152954), score: 0.75 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (ENSG00000148053), score: 0.75 OLFM1olfactomedin 1 (ENSG00000130558), score: 0.72 OPCMLopioid binding protein/cell adhesion molecule-like (ENSG00000183715), score: 0.72 OPRK1opioid receptor, kappa 1 (ENSG00000082556), score: 0.75 P2RY12purinergic receptor P2Y, G-protein coupled, 12 (ENSG00000169313), score: 0.77 PCDH19protocadherin 19 (ENSG00000165194), score: 0.92 PCDH20protocadherin 20 (ENSG00000197991), score: 0.91 PCDH9protocadherin 9 (ENSG00000184226), score: 0.73 PCSK1proprotein convertase subtilisin/kexin type 1 (ENSG00000175426), score: 0.92 PCSK2proprotein convertase subtilisin/kexin type 2 (ENSG00000125851), score: 0.73 PDE8Bphosphodiesterase 8B (ENSG00000113231), score: 0.79 PEX5Lperoxisomal biogenesis factor 5-like (ENSG00000114757), score: 0.79 PLCB1phospholipase C, beta 1 (phosphoinositide-specific) (ENSG00000182621), score: 0.9 PNOCprepronociceptin (ENSG00000168081), score: 0.76 PPFIA2protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 (ENSG00000139220), score: 0.76 PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozyme (ENSG00000138814), score: 0.74 PRICKLE1prickle homolog 1 (Drosophila) (ENSG00000139174), score: 0.72 PRICKLE2prickle homolog 2 (Drosophila) (ENSG00000163637), score: 0.84 PRKCAprotein kinase C, alpha (ENSG00000154229), score: 0.71 PRKCBprotein kinase C, beta (ENSG00000166501), score: 0.74 PRKG2protein kinase, cGMP-dependent, type II (ENSG00000138669), score: 0.87 PRMT8protein arginine methyltransferase 8 (ENSG00000111218), score: 0.71 R3HDM1R3H domain containing 1 (ENSG00000048991), score: 0.7 RAB3CRAB3C, member RAS oncogene family (ENSG00000152932), score: 0.74 RAPGEF5Rap guanine nucleotide exchange factor (GEF) 5 (ENSG00000136237), score: 0.72 RASD2RASD family, member 2 (ENSG00000100302), score: 0.74 RASGEF1ARasGEF domain family, member 1A (ENSG00000198915), score: 0.71 RGS20regulator of G-protein signaling 20 (ENSG00000147509), score: 0.77 RIMS3regulating synaptic membrane exocytosis 3 (ENSG00000117016), score: 0.73 RORBRAR-related orphan receptor B (ENSG00000198963), score: 0.86 RSPO2R-spondin 2 homolog (Xenopus laevis) (ENSG00000147655), score: 0.92 RXFP1relaxin/insulin-like family peptide receptor 1 (ENSG00000171509), score: 0.79 SATB2SATB homeobox 2 (ENSG00000119042), score: 0.79 SCG2secretogranin II (ENSG00000171951), score: 0.8 SCN3Bsodium channel, voltage-gated, type III, beta (ENSG00000166257), score: 0.78 SEMA3Asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (ENSG00000075213), score: 0.79 SEMA3Esema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (ENSG00000170381), score: 0.72 SERPINI1serpin peptidase inhibitor, clade I (neuroserpin), member 1 (ENSG00000163536), score: 0.78 SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2 (ENSG00000110436), score: 0.72 SLC24A2solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 (ENSG00000155886), score: 0.72 SLC24A4solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 (ENSG00000140090), score: 0.92 SLC32A1solute carrier family 32 (GABA vesicular transporter), member 1 (ENSG00000101438), score: 0.71 SLC39A12solute carrier family 39 (zinc transporter), member 12 (ENSG00000148482), score: 0.7 SLC4A10solute carrier family 4, sodium bicarbonate transporter, member 10 (ENSG00000144290), score: 0.78 SLC6A7solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 (ENSG00000011083), score: 0.76 SLC7A14solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 (ENSG00000013293), score: 0.71 SLC9A6solute carrier family 9 (sodium/hydrogen exchanger), member 6 (ENSG00000198689), score: 0.7 SNAP23synaptosomal-associated protein, 23kDa (ENSG00000092531), score: -0.63 SNTG1syntrophin, gamma 1 (ENSG00000147481), score: 0.9 SPRED1sprouty-related, EVH1 domain containing 1 (ENSG00000166068), score: 0.73 SSTsomatostatin (ENSG00000157005), score: 0.92 ST6GAL2ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 (ENSG00000144057), score: 0.75 ST6GALNAC5ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ENSG00000117069), score: 0.91 SULT4A1sulfotransferase family 4A, member 1 (ENSG00000130540), score: 0.7 SV2Bsynaptic vesicle glycoprotein 2B (ENSG00000185518), score: 0.7 SV2Csynaptic vesicle glycoprotein 2C (ENSG00000122012), score: 0.74 SYN2synapsin II (ENSG00000157152), score: 0.72 SYNJ1synaptojanin 1 (ENSG00000159082), score: 0.78 SYNPRsynaptoporin (ENSG00000163630), score: 0.72 SYT17synaptotagmin XVII (ENSG00000103528), score: 0.78 TAC1tachykinin, precursor 1 (ENSG00000006128), score: 0.87 TMEFF2transmembrane protein with EGF-like and two follistatin-like domains 2 (ENSG00000144339), score: 0.73 TMEM179transmembrane protein 179 (ENSG00000189203), score: 0.75 TMEM200Atransmembrane protein 200A (ENSG00000164484), score: 0.71 TMEM74transmembrane protein 74 (ENSG00000164841), score: 0.73 TNRtenascin R (restrictin, janusin) (ENSG00000116147), score: 0.74 TOXthymocyte selection-associated high mobility group box (ENSG00000198846), score: 0.77 TRHRthyrotropin-releasing hormone receptor (ENSG00000174417), score: 0.75 TRPC5transient receptor potential cation channel, subfamily C, member 5 (ENSG00000072315), score: 0.87 UNC5Aunc-5 homolog A (C. elegans) (ENSG00000113763), score: 0.73 UNC5Dunc-5 homolog D (C. elegans) (ENSG00000156687), score: 0.88 VIPvasoactive intestinal peptide (ENSG00000146469), score: 0.91 VSTM2AV-set and transmembrane domain containing 2A (ENSG00000170419), score: 0.86 VWC2Lvon Willebrand factor C domain-containing protein 2-like (ENSG00000174453), score: 0.89 WDR7WD repeat domain 7 (ENSG00000091157), score: 0.82 WNT7Awingless-type MMTV integration site family, member 7A (ENSG00000154764), score: 0.73 XYLT1xylosyltransferase I (ENSG00000103489), score: 0.76 ZDHHC22zinc finger, DHHC-type containing 22 (ENSG00000177108), score: 0.84 ZMAT4zinc finger, matrin type 4 (ENSG00000165061), score: 0.78 ZNF365zinc finger protein 365 (ENSG00000138311), score: 0.77
Id | species | tissue | sex | individual |
---|---|---|---|---|
hsa_br_f_ca1 | hsa | br | f | _ |
mdo_br_f_ca1 | mdo | br | f | _ |
mmu_br_m2_ca1 | mmu | br | m | 2 |
ggo_br_f_ca1 | ggo | br | f | _ |
oan_br_m_ca1 | oan | br | m | _ |
hsa_br_m2_ca1 | hsa | br | m | 2 |
hsa_br_m3_ca1 | hsa | br | m | 3 |
ptr_br_m4_ca1 | ptr | br | m | 4 |
mmu_br_f_ca1 | mmu | br | f | _ |
ppa_br_m_ca1 | ppa | br | m | _ |
ppy_br_f_ca1 | ppy | br | f | _ |
mmu_br_m1_ca1 | mmu | br | m | 1 |
ppy_br_m_ca1 | ppy | br | m | _ |
gga_br_m_ca1 | gga | br | m | _ |
mml_br_f_ca1 | mml | br | f | _ |
mml_br_m1_ca1 | mml | br | m | 1 |
hsa_br_m7_ca1 | hsa | br | m | 7 |
gga_br_f_ca1 | gga | br | f | _ |
mml_br_m2_ca1 | mml | br | m | 2 |