Previous module | Next module Module #529, TG: 2, TC: 1.6, 169 probes, 168 Entrez genes, 11 conditions

Help | Hide | Top Expression data


Expression data for module #529

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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regulation of heart rate

Any process that modulates the frequency or rate of heart contraction.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

circulatory system process

A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.

heart process

A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell surface receptor linked signaling pathway

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

G-protein coupled receptor protein signaling pathway

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

synaptic transmission

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

blood circulation

The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.

regulation of heart contraction

Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process by which the heart decreases in volume in a characteristic way to propel blood through the body.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

signaling pathway

The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms.

signaling process

Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.

signaling

The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.

signal transmission

The process whereby a signal is released and/or conveyed from one location to another.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

heart contraction

The multicellular organismal process by which the heart decreases in volume in a characteristic way to propel blood through the body.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

all

NA

signaling process

Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

synaptic transmission

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

heart contraction

The multicellular organismal process by which the heart decreases in volume in a characteristic way to propel blood through the body.

regulation of heart rate

Any process that modulates the frequency or rate of heart contraction.

regulation of heart contraction

Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process by which the heart decreases in volume in a characteristic way to propel blood through the body.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

synaptic vesicle

A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.

endomembrane system

A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.

vesicle membrane

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

coated vesicle

Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.

clathrin-coated vesicle

A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.

dendrite

A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

coated vesicle membrane

The lipid bilayer surrounding a coated vesicle.

clathrin coated vesicle membrane

The lipid bilayer surrounding a clathrin-coated vesicle.

synaptic vesicle membrane

The lipid bilayer surrounding a synaptic vesicle.

organelle membrane

The lipid bilayer surrounding an organelle.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

neuron projection

A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

synapse part

Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

synapse

The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

synapse part

Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

organelle membrane

The lipid bilayer surrounding an organelle.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

organelle membrane

The lipid bilayer surrounding an organelle.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

vesicle membrane

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle membrane

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

coated vesicle membrane

The lipid bilayer surrounding a coated vesicle.

synaptic vesicle

A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.

clathrin coated vesicle membrane

The lipid bilayer surrounding a clathrin-coated vesicle.

synaptic vesicle membrane

The lipid bilayer surrounding a synaptic vesicle.

Help | Hide | Top The GO tree — Molecular Function

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protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

peptide receptor activity

Combining with an extracellular or intracellular peptide to initiate a change in cell activity.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

receptor binding

Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

G-protein coupled receptor activity

A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

hormone activity

The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.

neuropeptide hormone activity

The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

neuropeptide receptor activity

Combining with a neuropeptide to initiate a change in cell activity.

G-protein coupled amine receptor activity

A receptor that binds an extracellular amine and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

peptide receptor activity, G-protein coupled

Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

passive transmembrane transporter activity

Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.

gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

neurotransmitter binding

Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.

peptide binding

Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.

neuropeptide binding

Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

neuropeptide receptor activity

Combining with a neuropeptide to initiate a change in cell activity.

peptide receptor activity

Combining with an extracellular or intracellular peptide to initiate a change in cell activity.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

neuropeptide receptor activity

Combining with a neuropeptide to initiate a change in cell activity.

peptide receptor activity, G-protein coupled

Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04080 1.361e-04 4.06 16
102 Neuroactive ligand-receptor interaction
04020 4.020e-02 2.707 9
68 Calcium signaling pathway

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

Id Pvalue ExpCount Count Size
X 3.741e-02 4.386 14
145

Help | Hide | Top Genes

Entrez genes

ACCN4amiloride-sensitive cation channel 4, pituitary (ENSG00000072182), score: 0.64 ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary) (ENSG00000141433), score: 0.63 AK2adenylate kinase 2 (ENSG00000004455), score: -0.57 AMZ1archaelysin family metallopeptidase 1 (ENSG00000174945), score: 0.66 ANKRA2ankyrin repeat, family A (RFXANK-like), 2 (ENSG00000164331), score: 0.69 ANO3anoctamin 3 (ENSG00000134343), score: 0.74 APCadenomatous polyposis coli (ENSG00000134982), score: 0.62 APEHN-acylaminoacyl-peptide hydrolase (ENSG00000164062), score: -0.61 ARPP21cAMP-regulated phosphoprotein, 21kDa (ENSG00000172995), score: 0.68 ATP6AP2ATPase, H+ transporting, lysosomal accessory protein 2 (ENSG00000182220), score: 0.63 AVPR1Barginine vasopressin receptor 1B (ENSG00000198049), score: 0.81 B3GALT1UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 (ENSG00000172318), score: 0.66 B3GALT5UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 (ENSG00000183778), score: 0.73 B4GALT1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (ENSG00000086062), score: -0.57 BCL11BB-cell CLL/lymphoma 11B (zinc finger protein) (ENSG00000127152), score: 0.79 BICD1bicaudal D homolog 1 (Drosophila) (ENSG00000151746), score: 0.63 BMP3bone morphogenetic protein 3 (ENSG00000152785), score: 0.93 BRS3bombesin-like receptor 3 (ENSG00000102239), score: 0.75 C18orf55chromosome 18 open reading frame 55 (ENSG00000075336), score: -0.65 C20orf103chromosome 20 open reading frame 103 (ENSG00000125869), score: 0.69 C8orf34chromosome 8 open reading frame 34 (ENSG00000165084), score: 0.81 CACNA1Ecalcium channel, voltage-dependent, R type, alpha 1E subunit (ENSG00000198216), score: 0.66 CACNG3calcium channel, voltage-dependent, gamma subunit 3 (ENSG00000006116), score: 0.68 CASTcalpastatin (ENSG00000153113), score: -0.61 CCDC111coiled-coil domain containing 111 (ENSG00000164306), score: -0.56 CD44CD44 molecule (Indian blood group) (ENSG00000026508), score: -0.59 CDH10cadherin 10, type 2 (T2-cadherin) (ENSG00000040731), score: 0.63 CDH12cadherin 12, type 2 (N-cadherin 2) (ENSG00000154162), score: 0.67 CDK17cyclin-dependent kinase 17 (ENSG00000059758), score: 0.83 CDS2CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 (ENSG00000101290), score: 0.74 CHCHD8coiled-coil-helix-coiled-coil-helix domain containing 8 (ENSG00000181924), score: -0.6 CHRM3cholinergic receptor, muscarinic 3 (ENSG00000133019), score: 0.62 CLCN3chloride channel 3 (ENSG00000109572), score: 0.72 CLVS2clavesin 2 (ENSG00000146352), score: 0.65 CNKSR2connector enhancer of kinase suppressor of Ras 2 (ENSG00000149970), score: 0.63 CNTN3contactin 3 (plasmacytoma associated) (ENSG00000113805), score: 0.64 CNTN5contactin 5 (ENSG00000149972), score: 0.94 COL25A1collagen, type XXV, alpha 1 (ENSG00000188517), score: 0.97 CPSF4cleavage and polyadenylation specific factor 4, 30kDa (ENSG00000160917), score: -0.6 CTNND1catenin (cadherin-associated protein), delta 1 (ENSG00000198561), score: -0.71 CTTNBP2cortactin binding protein 2 (ENSG00000077063), score: 0.66 CUL4Acullin 4A (ENSG00000139842), score: -0.57 DCLK3doublecortin-like kinase 3 (ENSG00000163673), score: 0.77 DCNdecorin (ENSG00000011465), score: -0.57 DCTN4dynactin 4 (p62) (ENSG00000132912), score: 0.64 DGKIdiacylglycerol kinase, iota (ENSG00000157680), score: 0.8 DLX6distal-less homeobox 6 (ENSG00000006377), score: 0.7 DRD2dopamine receptor D2 (ENSG00000149295), score: 0.7 DRP2dystrophin related protein 2 (ENSG00000102385), score: 0.62 DUSP19dual specificity phosphatase 19 (ENSG00000162999), score: 0.65 EPHA5EPH receptor A5 (ENSG00000145242), score: 0.91 EPHA7EPH receptor A7 (ENSG00000135333), score: 0.69 EPHA8EPH receptor A8 (ENSG00000070886), score: 0.65 EPHX4epoxide hydrolase 4 (ENSG00000172031), score: 0.82 EPS15epidermal growth factor receptor pathway substrate 15 (ENSG00000085832), score: 0.68 FADDFas (TNFRSF6)-associated via death domain (ENSG00000168040), score: -0.7 FAM164Afamily with sequence similarity 164, member A (ENSG00000104427), score: 0.69 FIBCD1fibrinogen C domain containing 1 (ENSG00000130720), score: 0.79 FRMPD4FERM and PDZ domain containing 4 (ENSG00000169933), score: 0.72 GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 2 (ENSG00000151834), score: 0.83 GABRA4gamma-aminobutyric acid (GABA) A receptor, alpha 4 (ENSG00000109158), score: 0.74 GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (ENSG00000136750), score: 0.73 GALNTL6UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6 (ENSG00000174473), score: 0.75 GPR139G protein-coupled receptor 139 (ENSG00000180269), score: 0.97 GPR149G protein-coupled receptor 149 (ENSG00000174948), score: 0.67 GRB10growth factor receptor-bound protein 10 (ENSG00000106070), score: -0.62 GRIA1glutamate receptor, ionotropic, AMPA 1 (ENSG00000155511), score: 0.63 GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B (ENSG00000150086), score: 0.68 GRM3glutamate receptor, metabotropic 3 (ENSG00000198822), score: 0.62 HHLA1HERV-H LTR-associating 1 (ENSG00000132297), score: 0.78 HTR1D5-hydroxytryptamine (serotonin) receptor 1D (ENSG00000179546), score: 0.67 HTR45-hydroxytryptamine (serotonin) receptor 4 (ENSG00000164270), score: 0.81 IAH1isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) (ENSG00000134330), score: -0.61 IL1RAPL1interleukin 1 receptor accessory protein-like 1 (ENSG00000169306), score: 0.86 IL1RAPL2interleukin 1 receptor accessory protein-like 2 (ENSG00000189108), score: 0.87 ITFG1integrin alpha FG-GAP repeat containing 1 (ENSG00000129636), score: 0.76 KCNA4potassium voltage-gated channel, shaker-related subfamily, member 4 (ENSG00000182255), score: 0.75 KCNJ6potassium inwardly-rectifying channel, subfamily J, member 6 (ENSG00000157542), score: 0.76 KCNK2potassium channel, subfamily K, member 2 (ENSG00000082482), score: 0.71 KCNQ3potassium voltage-gated channel, KQT-like subfamily, member 3 (ENSG00000184156), score: 0.74 KCNS2potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 (ENSG00000156486), score: 0.75 KCTD4potassium channel tetramerisation domain containing 4 (ENSG00000180332), score: 0.74 KIAA0391KIAA0391 (ENSG00000100890), score: -0.56 KIAA1279KIAA1279 (ENSG00000198954), score: 0.68 KIAA1467KIAA1467 (ENSG00000084444), score: 0.64 KIAA2022KIAA2022 (ENSG00000050030), score: 0.76 KRT9keratin 9 (ENSG00000171403), score: 0.63 LGI2leucine-rich repeat LGI family, member 2 (ENSG00000153012), score: 0.72 LMO1LIM domain only 1 (rhombotin 1) (ENSG00000166407), score: 0.67 LOC100291726similar to family with sequence similarity 70, member A (ENSG00000125355), score: 0.7 LOC100293905similar to gastrin-releasing peptide receptor (ENSG00000126010), score: 0.66 LPPR4lipid phosphate phosphatase-related protein type 4 (ENSG00000117600), score: 0.68 LRFN5leucine rich repeat and fibronectin type III domain containing 5 (ENSG00000165379), score: 0.68 LRRC26leucine rich repeat containing 26 (ENSG00000184709), score: 0.73 LRRC40leucine rich repeat containing 40 (ENSG00000066557), score: 0.69 LRRC4Cleucine rich repeat containing 4C (ENSG00000148948), score: 0.63 LRRC7leucine rich repeat containing 7 (ENSG00000033122), score: 0.8 MAML1mastermind-like 1 (Drosophila) (ENSG00000161021), score: -0.58 MAP2K1mitogen-activated protein kinase kinase 1 (ENSG00000169032), score: 0.67 MAP3K3mitogen-activated protein kinase kinase kinase 3 (ENSG00000198909), score: -0.61 MAPK8mitogen-activated protein kinase 8 (ENSG00000107643), score: 0.7 MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2 (ENSG00000162889), score: -0.62 MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2 (ENSG00000139915), score: 0.75 MLXIPMLX interacting protein (ENSG00000175727), score: -0.67 MMP16matrix metallopeptidase 16 (membrane-inserted) (ENSG00000156103), score: 0.64 MYO16myosin XVI (ENSG00000041515), score: 0.67 NCKAP1NCK-associated protein 1 (ENSG00000061676), score: 0.66 NDST4N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 (ENSG00000138653), score: 0.67 NETO1neuropilin (NRP) and tolloid (TLL)-like 1 (ENSG00000166342), score: 0.62 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (ENSG00000109320), score: -0.66 NPY2Rneuropeptide Y receptor Y2 (ENSG00000185149), score: 0.89 NPY5Rneuropeptide Y receptor Y5 (ENSG00000164129), score: 0.76 NRSN1neurensin 1 (ENSG00000152954), score: 0.64 NTSneurotensin (ENSG00000133636), score: 1 OLIG3oligodendrocyte transcription factor 3 (ENSG00000177468), score: 0.67 OPRK1opioid receptor, kappa 1 (ENSG00000082556), score: 0.67 OSTF1osteoclast stimulating factor 1 (ENSG00000134996), score: -0.62 OTOFotoferlin (ENSG00000115155), score: 0.81 P2RY12purinergic receptor P2Y, G-protein coupled, 12 (ENSG00000169313), score: 0.66 PCDH20protocadherin 20 (ENSG00000197991), score: 0.7 PDE10Aphosphodiesterase 10A (ENSG00000112541), score: 0.62 PENKproenkephalin (ENSG00000181195), score: 0.71 PEX5Lperoxisomal biogenesis factor 5-like (ENSG00000114757), score: 0.62 PLCB1phospholipase C, beta 1 (phosphoinositide-specific) (ENSG00000182621), score: 0.66 PNOCprepronociceptin (ENSG00000168081), score: 0.66 PPM1Eprotein phosphatase, Mg2+/Mn2+ dependent, 1E (ENSG00000175175), score: 0.63 PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozyme (ENSG00000138814), score: 0.67 PRCPprolylcarboxypeptidase (angiotensinase C) (ENSG00000137509), score: -0.56 PSKH1protein serine kinase H1 (ENSG00000159792), score: -0.57 QARSglutaminyl-tRNA synthetase (ENSG00000172053), score: -0.58 RAB3GAP2RAB3 GTPase activating protein subunit 2 (non-catalytic) (ENSG00000118873), score: 0.74 RASD2RASD family, member 2 (ENSG00000100302), score: 0.62 RGS7BPregulator of G-protein signaling 7 binding protein (ENSG00000186479), score: 0.68 RGS8regulator of G-protein signaling 8 (ENSG00000135824), score: 0.75 RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 1 (ENSG00000137275), score: -0.58 RPS6KC1ribosomal protein S6 kinase, 52kDa, polypeptide 1 (ENSG00000136643), score: 0.71 SCAMP1secretory carrier membrane protein 1 (ENSG00000085365), score: 0.7 SCG2secretogranin II (ENSG00000171951), score: 0.68 SEMA3Asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (ENSG00000075213), score: 0.8 SEMA3Esema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (ENSG00000170381), score: 0.65 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (ENSG00000197632), score: 0.65 SGTBsmall glutamine-rich tetratricopeptide repeat (TPR)-containing, beta (ENSG00000197860), score: 0.68 SLC32A1solute carrier family 32 (GABA vesicular transporter), member 1 (ENSG00000101438), score: 0.7 SLC39A13solute carrier family 39 (zinc transporter), member 13 (ENSG00000165915), score: -0.56 SLC5A7solute carrier family 5 (choline transporter), member 7 (ENSG00000115665), score: 0.86 SLC6A11solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (ENSG00000132164), score: 0.62 SNAP23synaptosomal-associated protein, 23kDa (ENSG00000092531), score: -0.57 SSTsomatostatin (ENSG00000157005), score: 0.62 STIM2stromal interaction molecule 2 (ENSG00000109689), score: 0.63 STX12syntaxin 12 (ENSG00000117758), score: 0.69 SV2Csynaptic vesicle glycoprotein 2C (ENSG00000122012), score: 0.71 SYNJ1synaptojanin 1 (ENSG00000159082), score: 0.72 TAC1tachykinin, precursor 1 (ENSG00000006128), score: 0.8 TBC1D19TBC1 domain family, member 19 (ENSG00000109680), score: 0.66 TFAP2Dtranscription factor AP-2 delta (activating enhancer binding protein 2 delta) (ENSG00000008197), score: 0.81 TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (ENSG00000198959), score: -0.57 THSD7Athrombospondin, type I, domain containing 7A (ENSG00000005108), score: 0.74 THY1Thy-1 cell surface antigen (ENSG00000154096), score: 0.62 TMEFF2transmembrane protein with EGF-like and two follistatin-like domains 2 (ENSG00000144339), score: 0.66 TMEM200Atransmembrane protein 200A (ENSG00000164484), score: 0.81 TPBGtrophoblast glycoprotein (ENSG00000146242), score: 0.69 TRHRthyrotropin-releasing hormone receptor (ENSG00000174417), score: 0.63 TRPC1transient receptor potential cation channel, subfamily C, member 1 (ENSG00000144935), score: 0.68 TRPC5transient receptor potential cation channel, subfamily C, member 5 (ENSG00000072315), score: 0.94 VSTM2AV-set and transmembrane domain containing 2A (ENSG00000170419), score: 0.64 WNT3Awingless-type MMTV integration site family, member 3A (ENSG00000154342), score: 0.72 WNT4wingless-type MMTV integration site family, member 4 (ENSG00000162552), score: 0.75 ZC3H12Bzinc finger CCCH-type containing 12B (ENSG00000102053), score: 0.63

Non-Entrez genes

ENSG00000180269Unknown, score: 0.64

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Id species tissue sex individual
oan_cb_f_ca1 oan cb f _
oan_cb_m_ca1 oan cb m _
mdo_br_m_ca1 mdo br m _
mmu_br_m2_ca1 mmu br m 2
mmu_br_f_ca1 mmu br f _
mmu_br_m1_ca1 mmu br m 1
mdo_br_f_ca1 mdo br f _
gga_br_m_ca1 gga br m _
oan_br_f_ca1 oan br f _
gga_br_f_ca1 gga br f _
oan_br_m_ca1 oan br m _

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© 2008-2010 Computational Biology Group, Department of Medical Genetics, University of Lausanne, Switzerland