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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

immune effector process

Any process of the immune system that occurs as part of an immune response.

activation of immune response

Any process that initiates an immune response.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

acute inflammatory response

Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.

activation of plasma proteins involved in acute inflammatory response

Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

carbohydrate metabolic process

The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.

monosaccharide metabolic process

The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.

glucose metabolic process

The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.

alcohol metabolic process

The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

protein maturation by peptide bond cleavage

The hydrolysis of a peptide bond or bonds within a protein as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

cellular amino acid derivative metabolic process

The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.

lipid metabolic process

The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

cellular aromatic compound metabolic process

The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.

coenzyme metabolic process

The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.

nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

humoral immune response

An immune response mediated through a body fluid.

hemostasis

The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

bile acid metabolic process

The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.

negative regulation of coagulation

Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.

catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

aromatic amino acid family metabolic process

The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

aromatic amino acid family catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

amine catabolic process

The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

response to external stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to organic substance

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.

gene expression

The process by which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.

lipid catabolic process

The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

organic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.

protein processing

Any protein maturation process achieved by the cleavage of peptide bonds.

hexose metabolic process

The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.

aromatic compound catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

carboxylic acid metabolic process

The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

regulation of blood coagulation

Any process that modulates the frequency, rate or extent of blood coagulation.

negative regulation of blood coagulation

Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation.

regulation of response to external stimulus

Any process that modulates the frequency, rate or extent of a response to an external stimulus.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

monocarboxylic acid metabolic process

The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

dicarboxylic acid metabolic process

The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).

cellular amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

cellular carbohydrate metabolic process

The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.

small molecule metabolic process

The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass.

small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.

carboxylic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

coagulation

The process by which a fluid solution, or part of it, changes into a solid or semisolid mass.

regulation of coagulation

Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass.

positive regulation of coagulation

Any process that activates or increases the frequency, rate or extent of coagulation.

regulation of body fluid levels

Any process that modulates the levels of body fluids.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

cofactor metabolic process

The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

positive regulation of multicellular organismal process

Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

protein maturation

Any process leading to the attainment of the full functional capacity of a protein.

regulation of wound healing

Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

regulation of response to stress

Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

all

NA

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

positive regulation of multicellular organismal process

Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

immune effector process

Any process of the immune system that occurs as part of an immune response.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of coagulation

Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass.

positive regulation of multicellular organismal process

Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

positive regulation of coagulation

Any process that activates or increases the frequency, rate or extent of coagulation.

negative regulation of coagulation

Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of response to stress

Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

regulation of response to external stimulus

Any process that modulates the frequency, rate or extent of a response to an external stimulus.

regulation of body fluid levels

Any process that modulates the levels of body fluids.

cellular amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

organic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.

protein maturation

Any process leading to the attainment of the full functional capacity of a protein.

organic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.

aromatic compound catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

cellular carbohydrate metabolic process

The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.

lipid catabolic process

The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

monosaccharide metabolic process

The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

activation of immune response

Any process that initiates an immune response.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

negative regulation of blood coagulation

Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation.

negative regulation of coagulation

Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.

regulation of blood coagulation

Any process that modulates the frequency, rate or extent of blood coagulation.

positive regulation of coagulation

Any process that activates or increases the frequency, rate or extent of coagulation.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

regulation of blood coagulation

Any process that modulates the frequency, rate or extent of blood coagulation.

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

aromatic amino acid family metabolic process

The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

aromatic amino acid family catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

negative regulation of blood coagulation

Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation.

regulation of blood coagulation

Any process that modulates the frequency, rate or extent of blood coagulation.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

regulation of wound healing

Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.

aromatic amino acid family catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

carboxylic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.

activation of plasma proteins involved in acute inflammatory response

Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.

bile acid metabolic process

The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cell fraction

A generic term for parts of cells prepared by disruptive biochemical techniques.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

stored secretory granule

A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.

endomembrane system

A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

organelle membrane

The lipid bilayer surrounding an organelle.

platelet alpha granule

A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).

platelet alpha granule lumen

The volume enclosed by the membrane of the platelet alpha granule.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

membrane-enclosed lumen

The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

vesicle lumen

The volume enclosed by the membrane or protein that forms a vesicle.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

nuclear membrane-endoplasmic reticulum network

The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

organelle lumen

The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

endoplasmic reticulum part

Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

tricarboxylic acid cycle enzyme complex

Any of the heteromeric enzymes that act in the TCA cycle.

cytoplasmic membrane-bounded vesicle lumen

The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.

subsynaptic reticulum

An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.

all

NA

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

organelle lumen

The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.

organelle membrane

The lipid bilayer surrounding an organelle.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

organelle membrane

The lipid bilayer surrounding an organelle.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

nuclear membrane-endoplasmic reticulum network

The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

nuclear membrane-endoplasmic reticulum network

The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

vesicle lumen

The volume enclosed by the membrane or protein that forms a vesicle.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

cytoplasmic membrane-bounded vesicle lumen

The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

endoplasmic reticulum part

Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

tricarboxylic acid cycle enzyme complex

Any of the heteromeric enzymes that act in the TCA cycle.

subsynaptic reticulum

An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.

cytoplasmic membrane-bounded vesicle lumen

The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.

endoplasmic reticulum part

Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.

endoplasmic reticulum part

Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.

platelet alpha granule lumen

The volume enclosed by the membrane of the platelet alpha granule.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

metal ion binding

Interacting selectively and non-covalently with any metal ion.

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

vitamin binding

Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.

pyridoxal phosphate binding

Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

carboxylic acid binding

Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

ion binding

Interacting selectively and non-covalently with ions, charged atoms or groups of atoms.

cation binding

Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge.

transition metal ion binding

Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

cofactor binding

Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.

vitamin B6 binding

Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.

all

NA

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

pyridoxal phosphate binding

Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0006082	7.800e-09	17.45	49 AARS2, ACOT12, ACSL5, AFMID, AGXT, AKR1D1, AMDHD1, ASPG, ATP8B1, AVPR1A, BCKDHB, CCBL1, CDO1, CTH, CYP39A1, CYP7B1, DLST, FGF19, FH, GARS, GCH1, GCLM, GGH, GNMT, GOT1, HAL, HAO1, HGD, IGF1, KMO, LIPC, LPIN2, MAT1A, ME2, NPC1, NR5A2, OTC, P4HA1, PAH, PCK1, PCK2, PEX7, RBP4, SGPL1, SLC7A2, SLC7A6, SUCLG1, TAT, TDO2	228	organic acid metabolic process
GO:0019752	7.800e-09	17.45	49 AARS2, ACOT12, ACSL5, AFMID, AGXT, AKR1D1, AMDHD1, ASPG, ATP8B1, AVPR1A, BCKDHB, CCBL1, CDO1, CTH, CYP39A1, CYP7B1, DLST, FGF19, FH, GARS, GCH1, GCLM, GGH, GNMT, GOT1, HAL, HAO1, HGD, IGF1, KMO, LIPC, LPIN2, MAT1A, ME2, NPC1, NR5A2, OTC, P4HA1, PAH, PCK1, PCK2, PEX7, RBP4, SGPL1, SLC7A2, SLC7A6, SUCLG1, TAT, TDO2	228	carboxylic acid metabolic process
GO:0043436	7.800e-09	17.45	49 AARS2, ACOT12, ACSL5, AFMID, AGXT, AKR1D1, AMDHD1, ASPG, ATP8B1, AVPR1A, BCKDHB, CCBL1, CDO1, CTH, CYP39A1, CYP7B1, DLST, FGF19, FH, GARS, GCH1, GCLM, GGH, GNMT, GOT1, HAL, HAO1, HGD, IGF1, KMO, LIPC, LPIN2, MAT1A, ME2, NPC1, NR5A2, OTC, P4HA1, PAH, PCK1, PCK2, PEX7, RBP4, SGPL1, SLC7A2, SLC7A6, SUCLG1, TAT, TDO2	228	oxoacid metabolic process
GO:0042180	1.657e-08	17.83	49 AARS2, ACOT12, ACSL5, AFMID, AGXT, AKR1D1, AMDHD1, ASPG, ATP8B1, AVPR1A, BCKDHB, CCBL1, CDO1, CTH, CYP39A1, CYP7B1, DLST, FGF19, FH, GARS, GCH1, GCLM, GGH, GNMT, GOT1, HAL, HAO1, HGD, IGF1, KMO, LIPC, LPIN2, MAT1A, ME2, NPC1, NR5A2, OTC, P4HA1, PAH, PCK1, PCK2, PEX7, RBP4, SGPL1, SLC7A2, SLC7A6, SUCLG1, TAT, TDO2	233	cellular ketone metabolic process
GO:0044106	5.538e-06	8.724	28 AARS2, AFMID, AGXT, AMDHD1, ASPG, BCKDHB, CCBL1, CDO1, CTH, ETNK2, GARS, GCH1, GCLM, GGH, GNMT, GOT1, HAL, HGD, KMO, LIPC, MAT1A, OTC, PAH, PEMT, SLC7A2, SLC7A6, TAT, TDO2	114	cellular amine metabolic process
GO:0009308	6.203e-06	11.55	33 AARS2, ACER3, AFMID, AGXT, AMDHD1, ASPG, BCKDHB, CCBL1, CDO1, CTBS, CTH, ETNK2, GARS, GCH1, GCLM, GGH, GNMT, GOT1, HAL, HGD, IMPAD1, KMO, LIPC, LYVE1, MAT1A, OTC, P4HA1, PAH, PEMT, SLC7A2, SLC7A6, TAT, TDO2	151	amine metabolic process
GO:0006520	1.003e-05	6.887	24 AARS2, AFMID, AGXT, AMDHD1, ASPG, BCKDHB, CCBL1, CDO1, CTH, GARS, GCLM, GGH, GNMT, GOT1, HAL, HGD, KMO, MAT1A, OTC, PAH, SLC7A2, SLC7A6, TAT, TDO2	90	cellular amino acid metabolic process
GO:0006519	1.020e-05	10.1	30 AARS2, AFMID, AGXT, AMDHD1, ASPG, BCKDHB, CCBL1, CDO1, CTH, ETNK2, GARS, GCH1, GCLM, GGH, GLO1, GNMT, GOT1, HAL, HGD, KMO, LIPC, MAT1A, OTC, P4HA1, PAH, PEMT, SLC7A2, SLC7A6, TAT, TDO2	132	cellular amino acid and derivative metabolic process
GO:0044281	1.915e-05	46.07	81 AARS2, ABCA1, ACER3, ACOT12, ACSL5, ADPGK, AFMID, AGXT, AKAP12, AKR1D1, AMDHD1, ARFGAP3, ASPG, ATP8B1, AVPR1A, BCKDHB, CA6, CCBL1, CDO1, CRYAB, CTH, CYB5R2, CYP2R1, CYP39A1, CYP7B1, DHTKD1, DLST, ETNK2, EVI5, FGF19, FH, FZD2, GARS, GBE1, GCH1, GCLM, GGH, GK5, GLO1, GMPR, GNMT, GOT1, H6PD, HAL, HAO1, HGD, IGF1, IL6ST, KMO, LIPC, LPIN2, MAT1A, ME2, MTAP, NPC1, NR5A2, NT5E, ONECUT1, OTC, P4HA1, PAH, PANK1, PCK1, PCK2, PDE3B, PEMT, PEX7, PHKA2, PYGL, RBP4, SCARB1, SGPL1, SGSM2, SLC7A2, SLC7A6, SUCLG1, TAT, TBC1D8B, TDO2, TTPA, VLDLR	602	small molecule metabolic process
GO:0019439	2.987e-05	0.6122	7 AFMID, EPHX1, HGD, KMO, PAH, TAT, TDO2	8	aromatic compound catabolic process
GO:0009074	4.797e-05	0.4591	6 AFMID, HGD, KMO, PAH, TAT, TDO2	6	aromatic amino acid family catabolic process
GO:0009056	4.839e-05	31.83	61 ACSL5, ADPGK, AFMID, AKR1D1, AMBP, AMBRA1, AMDHD1, ANAPC2, ANAPC4, ARFGAP3, ASPG, BCKDHB, BTRC, CDO1, CLN5, CLPX, CTBS, CYP39A1, DERL1, DERL3, DHTKD1, DLST, EPHX1, EVI5, FBXO4, FH, GCH1, GOT1, H6PD, HAL, HAO1, HGD, HM13, IDE, IGF1, KMO, LIPC, LYVE1, MTPAP, NAGA, NCSTN, NPC1, NT5E, PAFAH1B2, PAFAH2, PAH, PDE3B, PEX7, PLA2G12B, PSEN2, PYGL, RNF103, SCARB1, SGPL1, SGSM2, SUCLG1, TAT, TBC1D8B, TDO2, USP20, ZMPSTE24	416	catabolic process
GO:0016054	5.493e-05	3.673	16 ACSL5, AFMID, AKR1D1, AMDHD1, BCKDHB, CDO1, CYP39A1, GOT1, HAL, HAO1, HGD, KMO, PAH, PEX7, TAT, TDO2	48	organic acid catabolic process
GO:0046395	5.493e-05	3.673	16 ACSL5, AFMID, AKR1D1, AMDHD1, BCKDHB, CDO1, CYP39A1, GOT1, HAL, HAO1, HGD, KMO, PAH, PEX7, TAT, TDO2	48	carboxylic acid catabolic process
GO:0006629	1.694e-04	23.65	48 ABCA1, ACER3, ACOT12, ACSL5, AKR1D1, ASPG, ATP8B1, AVPR1A, CEPT1, COL4A3BP, CRLS1, CYB5R2, CYP2R1, CYP39A1, CYP7B1, ESR1, ETNK2, FGF19, GPLD1, HAO1, IL6ST, INPP5E, LIPC, LPCAT3, LPIN2, MTTP, NAGA, NPC1, NR5A2, OSBPL2, PAFAH1B2, PAFAH2, PCK1, PDE3B, PEMT, PEX7, PIGK, PIGL, PIP5K1C, PLA2G12B, RBP4, SCARB1, SDR42E1, SERINC5, SGPL1, STARD5, TTPA, VLDLR	309	lipid metabolic process
GO:0065008	3.327e-04	48.21	79 A1CF, ABCA1, ACVR2A, AKR1D1, ALB, ANAPC2, APBB2, AVPR1A, BDKRB1, BMP2, CAPRIN2, CDO1, CISH, CLDN1, CLN5, COL4A3BP, CPB2, CRYAB, CTH, DERL1, ERP44, ESR1, F10, F2, F9, FAM3D, FBXO4, FGB, FGFR1, FGG, FH, FN1, FZD2, GAS2, GCH1, GCLM, GNA12, GOT1, HPX, HRG, IBTK, IDE, IGF1, IGFBP1, IL6ST, LIPC, MAP2K5, MYH10, NOP58, NPC1, NR5A2, OTC, PAH, PCK1, PDE3B, PDIA5, PLAT, PRDX4, PROZ, PSEN2, PTCH1, PYGL, QSOX1, RBP4, SCARB1, SERPINC1, SERPINE2, SERPINF2, SGPL1, SLC16A2, SLC30A1, SLC30A7, TLN2, TLR3, TXNDC12, TXNDC15, TXNRD1, VTN, XCR1	630	regulation of biological quality
GO:0009063	4.528e-04	2.143	11 AFMID, AMDHD1, BCKDHB, CDO1, GOT1, HAL, HGD, KMO, PAH, TAT, TDO2	28	cellular amino acid catabolic process
GO:0050817	5.016e-04	3.903	15 CPB2, F10, F2, F9, FGB, FGG, GNA12, HRG, PLAT, PROZ, PSEN2, SERPINC1, SERPINE2, SERPINF2, VTN	51	coagulation
GO:0008206	5.414e-04	0.8417	7 AKR1D1, ATP8B1, CYP39A1, CYP7B1, FGF19, NPC1, NR5A2	11	bile acid metabolic process
GO:0009310	6.332e-04	2.219	11 AFMID, AMDHD1, BCKDHB, CDO1, GOT1, HAL, HGD, KMO, PAH, TAT, TDO2	29	amine catabolic process
GO:0006956	6.666e-04	0.6122	6 C5, C8A, C8G, MASP1, MASP2, VSIG4	8	complement activation
GO:0009611	9.282e-04	16.15	35 BDKRB1, BMP2, C5, C8A, C8G, CDO1, CPB2, F10, F2, F9, FGB, FGG, FN1, GNA12, HRG, IGF1, IGFBP1, IL6ST, LY75, LYVE1, MASP1, MASP2, NT5E, PLAT, PROZ, SCARB1, SDC2, SERPINA10, SERPINC1, SERPINE2, SERPINF2, TLR3, VSIG4, VTN, XCR1	211	response to wounding
GO:0007596	1.278e-03	3.75	14 CPB2, F10, F2, F9, FGB, FGG, GNA12, HRG, PLAT, PROZ, SERPINC1, SERPINE2, SERPINF2, VTN	49	blood coagulation
GO:0043648	1.286e-03	1.607	9 DLST, FH, GOT1, ME2, PAH, PCK1, PCK2, SUCLG1, TAT	21	dicarboxylic acid metabolic process
GO:0006066	1.445e-03	13.16	30 ABCA1, ACER3, ADPGK, AKR1D1, CRYAB, CYB5R2, CYP39A1, CYP7B1, DHTKD1, ETNK2, GBE1, GCH1, GK5, GNMT, GOT1, H6PD, HAO1, IGF1, IL6ST, LIPC, ONECUT1, PAH, PCK1, PCK2, PEMT, PHKA2, PYGL, RBP4, SCARB1, VLDLR	172	alcohol metabolic process
GO:0044248	1.465e-03	26.63	49 ACSL5, AFMID, AKR1D1, AMBP, AMBRA1, AMDHD1, ANAPC2, ANAPC4, ARFGAP3, BCKDHB, BTRC, CDO1, CLPX, CYP39A1, DERL1, DERL3, DLST, EPHX1, EVI5, FBXO4, FH, GCH1, GOT1, HAL, HAO1, HGD, HM13, IDE, IGF1, KMO, LIPC, MTPAP, NAGA, NCSTN, NPC1, NT5E, PAH, PDE3B, PEX7, PSEN2, RNF103, SGPL1, SGSM2, SUCLG1, TAT, TBC1D8B, TDO2, USP20, ZMPSTE24	348	cellular catabolic process
GO:0008202	1.532e-03	5.892	18 ABCA1, AKR1D1, ATP8B1, CYB5R2, CYP2R1, CYP39A1, CYP7B1, ESR1, FGF19, LIPC, NPC1, NR5A2, OSBPL2, SCARB1, SDR42E1, SGPL1, STARD5, VLDLR	77	steroid metabolic process
GO:0002541	1.570e-03	0.6887	6 C5, C8A, C8G, MASP1, MASP2, VSIG4	9	activation of plasma proteins involved in acute inflammatory response
GO:0009072	1.570e-03	0.6887	6 AFMID, HGD, KMO, PAH, TAT, TDO2	9	aromatic amino acid family metabolic process
GO:0007599	1.582e-03	3.826	14 CPB2, F10, F2, F9, FGB, FGG, GNA12, HRG, PLAT, PROZ, SERPINC1, SERPINE2, SERPINF2, VTN	50	hemostasis
GO:0006575	2.077e-03	4.438	15 AFMID, CCBL1, CDO1, CTH, ETNK2, GCH1, GCLM, GLO1, GNMT, KMO, LIPC, P4HA1, PAH, PEMT, TDO2	58	cellular amino acid derivative metabolic process
GO:0042060	2.586e-03	6.734	19 CPB2, F10, F2, F9, FGB, FGG, GNA12, HRG, IGF1, IGFBP1, PLAT, PROZ, SCARB1, SDC2, SERPINA10, SERPINC1, SERPINE2, SERPINF2, VTN	88	wound healing
GO:0044282	2.741e-03	11.71	27 ACSL5, ADPGK, AFMID, AKR1D1, AMDHD1, ARFGAP3, BCKDHB, CDO1, CYP39A1, DHTKD1, EVI5, GCH1, GOT1, H6PD, HAL, HAO1, HGD, IGF1, KMO, NT5E, PAH, PDE3B, PEX7, SGSM2, TAT, TBC1D8B, TDO2	153	small molecule catabolic process
GO:0030195	3.083e-03	0.7652	6 CPB2, F2, HRG, SERPINE2, SERPINF2, VTN	10	negative regulation of blood coagulation
GO:0051186	3.473e-03	5.204	16 ACOT12, AMBP, CIAO1, CTH, DLST, FH, GCH1, GCLM, GLO1, GPHN, H6PD, HPX, KMO, PANK1, SUCLG1, TDO2	68	cofactor metabolic process
GO:0006006	4.815e-03	4.285	14 ADPGK, CRYAB, DHTKD1, GBE1, GNMT, H6PD, IGF1, IL6ST, ONECUT1, PCK1, PCK2, PHKA2, PYGL, RBP4	56	glucose metabolic process
GO:0050818	4.822e-03	1.148	7 CPB2, F2, HRG, PSEN2, SERPINE2, SERPINF2, VTN	15	regulation of coagulation
GO:0006959	5.248e-03	1.53	8 C5, C8A, C8G, HPX, MASP1, MASP2, ST6GAL1, VSIG4	20	humoral immune response
GO:0016485	5.394e-03	2.831	11 C5, C8A, C8G, IHH, MASP1, MASP2, NCSTN, PSEN2, PTCH1, SERPINE2, VSIG4	37	protein processing
GO:0051604	5.394e-03	2.831	11 C5, C8A, C8G, IHH, MASP1, MASP2, NCSTN, PSEN2, PTCH1, SERPINE2, VSIG4	37	protein maturation
GO:0050819	5.495e-03	0.8417	6 CPB2, F2, HRG, SERPINE2, SERPINF2, VTN	11	negative regulation of coagulation
GO:0006950	6.447e-03	47.14	72 ALB, AMBP, ATMIN, AVPR1A, BDKRB1, BMP2, C5, C8A, C8G, CDO1, COL4A3BP, CPB2, CREB3L3, CRYAB, DERL1, DERL3, EDEM3, EGFR, ERP44, F10, F2, F9, FAF2, FGB, FGF19, FGG, FN1, GCH1, GCLM, GMPR, GNA12, GPR132, GPX7, HAO1, HPX, HRG, IGF1, IGFBP1, IL6ST, KMO, LEAP2, LY75, LYVE1, MAPK8IP3, MASP1, MASP2, NPC1, NT5E, PDIA5, PLAT, PROZ, PSEN2, SCARB1, SDC2, SERPINA10, SERPINC1, SERPINE2, SERPINF2, SH3RF1, STAB2, STK39, TAT, TLR3, TOR1B, TP53BP1, TP53INP1, UBXN4, VLDLR, VSIG4, VTN, XCR1, XRCC6BP1	616	response to stress
GO:0006732	6.605e-03	3.903	13 ACOT12, CTH, DLST, FH, GCH1, GCLM, GLO1, GPHN, H6PD, KMO, PANK1, SUCLG1, TDO2	51	coenzyme metabolic process
GO:0010033	7.007e-03	25.56	45 ACSL5, AGXT, AVPR1A, BCKDHB, BDKRB1, BMP2, BTRC, CDH1, CDO1, CREB3L3, CRYAB, CYP7B1, DDOST, DERL1, DERL3, EDEM3, EGFR, EPHX1, ERP44, ESR1, FAF2, GCH1, GGH, GOT1, HPX, IGF1R, IGFBP1, IHH, IL6ST, PCK1, PCK2, PDE3B, PEMT, PLAT, PTCH1, RBP4, SCARB1, SDC2, SERPINF2, TAT, TLR3, TOR1B, UBXN4, VLDLR, XCR1	334	response to organic substance
GO:0002526	8.603e-03	2.525	10 C5, C8A, C8G, F2, FN1, IL6ST, MASP1, MASP2, SERPINF2, VSIG4	33	acute inflammatory response
GO:0050820	8.864e-03	0.6122	5 CPB2, F2, HRG, PSEN2, SERPINF2	8	positive regulation of coagulation
GO:0030193	8.968e-03	0.9183	6 CPB2, F2, HRG, SERPINE2, SERPINF2, VTN	12	regulation of blood coagulation
GO:0016042	9.123e-03	4.591	14 ACSL5, AKR1D1, ASPG, CYP39A1, HAO1, LIPC, NAGA, PAFAH1B2, PAFAH2, PDE3B, PEX7, PLA2G12B, SCARB1, SGPL1	60	lipid catabolic process
GO:0055088	1.034e-02	1.301	7 ABCA1, COL4A3BP, GOT1, LIPC, NPC1, NR5A2, SCARB1	17	lipid homeostasis
GO:0006957	1.114e-02	0.3826	4 C5, C8A, C8G, VSIG4	5	complement activation, alternative pathway
GO:0051917	1.114e-02	0.3826	4 CPB2, F2, HRG, SERPINF2	5	regulation of fibrinolysis
GO:0051918	1.114e-02	0.3826	4 CPB2, F2, HRG, SERPINF2	5	negative regulation of fibrinolysis
GO:0061041	1.376e-02	0.9948	6 CPB2, F2, HRG, SERPINE2, SERPINF2, VTN	13	regulation of wound healing
GO:0032787	1.465e-02	9.795	22 ACOT12, ACSL5, AGXT, AKR1D1, ATP8B1, AVPR1A, CYP39A1, CYP7B1, FGF19, GCH1, GNMT, HAO1, IGF1, LIPC, LPIN2, NPC1, NR5A2, P4HA1, PCK1, PCK2, PEX7, RBP4	128	monocarboxylic acid metabolic process
GO:0006869	1.467e-02	4.285	13 ABCA1, ABCA5, ABCD3, ACSL5, ATP8B1, COL4A3BP, LIPC, NPC1, OSBPL2, RBP4, SCARB1, STARD5, VLDLR	56	lipid transport
GO:0002455	1.585e-02	0.6887	5 C5, C8A, C8G, HPX, MASP2	9	humoral immune response mediated by circulating immunoglobulin
GO:0009309	1.678e-02	1.837	8 AGXT, CDO1, CTH, ETNK2, GCH1, GOT1, OTC, PAH	24	amine biosynthetic process
GO:0055114	1.706e-02	14.77	29 AKR1D1, BCKDHB, C1orf27, CDO1, CYB5R2, CYP2R1, CYP39A1, CYP7B1, DHRS11, DHTKD1, GCLM, GMPR, GPX7, H6PD, HAO1, HGD, IYD, KMO, ME2, P4HA1, P4HTM, PAH, PDIA5, PRDX4, QSOX1, SDR42E1, TDO2, TXNDC12, TXNRD1	193	oxidation reduction
GO:0008652	2.016e-02	1.071	6 AGXT, CDO1, CTH, GOT1, OTC, PAH	14	cellular amino acid biosynthetic process
GO:0006986	2.135e-02	1.913	8 CREB3L3, DERL1, DERL3, EDEM3, ERP44, FAF2, TOR1B, UBXN4	25	response to unfolded protein
GO:0046486	2.233e-02	4.515	13 ACSL5, ETNK2, GPLD1, IL6ST, INPP5E, LIPC, PCK1, PEMT, PEX7, PIGK, PIGL, PIP5K1C, SERINC5	59	glycerolipid metabolic process
GO:0006534	2.453e-02	0.2296	3 CDO1, CTH, GCLM	3	cysteine metabolic process
GO:0006558	2.453e-02	0.2296	3 HGD, PAH, TAT	3	L-phenylalanine metabolic process
GO:0006559	2.453e-02	0.2296	3 HGD, PAH, TAT	3	L-phenylalanine catabolic process
GO:0006569	2.453e-02	0.2296	3 AFMID, KMO, TDO2	3	tryptophan catabolic process
GO:0042436	2.453e-02	0.2296	3 AFMID, KMO, TDO2	3	indole derivative catabolic process
GO:0046218	2.453e-02	0.2296	3 AFMID, KMO, TDO2	3	indolalkylamine catabolic process
GO:0006536	2.460e-02	0.4591	4 AMDHD1, GCLM, GOT1, TAT	6	glutamate metabolic process
GO:0006699	2.460e-02	0.4591	4 AKR1D1, CYP39A1, CYP7B1, FGF19	6	bile acid biosynthetic process
GO:0006958	2.460e-02	0.4591	4 C5, C8A, C8G, MASP2	6	complement activation, classical pathway
GO:0019835	2.460e-02	0.4591	4 C5, C8A, C8G, MMD	6	cytolysis
GO:0030194	2.460e-02	0.4591	4 CPB2, F2, HRG, SERPINF2	6	positive regulation of blood coagulation
GO:0042730	2.460e-02	0.4591	4 CPB2, F2, HRG, SERPINF2	6	fibrinolysis
GO:0048710	2.460e-02	0.4591	4 BMP2, F2, IL6ST, SERPINE2	6	regulation of astrocyte differentiation
GO:0006829	2.535e-02	0.7652	5 SLC30A1, SLC30A6, SLC30A7, SLC39A8, SLC39A9	10	zinc ion transport
GO:0035272	2.543e-02	1.53	7 CDH1, EGFR, FGFR1, HGF, IGF1, IGF1R, TWSG1	20	exocrine system development
GO:0006725	2.743e-02	3.52	11 AFMID, EPHX1, GCH1, GNMT, GPHN, HGD, KMO, PAH, PEMT, TAT, TDO2	46	cellular aromatic compound metabolic process
GO:0022612	2.743e-02	3.52	11 BTRC, CDH1, CYP7B1, EGFR, ESR1, FGFR1, HGF, IGF1, IGF1R, PTCH1, TWSG1	46	gland morphogenesis
GO:0009064	2.782e-02	1.148	6 AMDHD1, GCLM, GGH, GOT1, OTC, TAT	15	glutamine family amino acid metabolic process
GO:0010876	2.861e-02	4.668	13 ABCA1, ABCA5, ABCD3, ACSL5, ATP8B1, COL4A3BP, LIPC, NPC1, OSBPL2, RBP4, SCARB1, STARD5, VLDLR	61	lipid localization
GO:0042221	2.868e-02	39.94	60 ACSL5, AGXT, AVPR1A, BCKDHB, BDKRB1, BLMH, BMP2, BTRC, C5, CDH1, CDO1, CPB2, CREB3L3, CRYAB, CYP7B1, DDOST, DERL1, DERL3, EDEM3, EGFR, EPHX1, ERP44, ESR1, FAF2, FGB, FGG, GCH1, GCLM, GGH, GOT1, GPX7, HAO1, HPX, IGF1R, IGFBP1, IHH, IL6ST, LECT2, NPC1, PCK1, PCK2, PDE3B, PEMT, PLAT, PSEN2, PTCH1, RBP4, SCARB1, SDC2, SERPINC1, SERPINF2, SS18, TAT, TLR3, TOR1B, TTPA, UBXN4, VLDLR, WNT9A, XCR1	522	response to chemical stimulus
GO:0050878	2.986e-02	5.892	15 CDO1, CPB2, F10, F2, F9, FGB, FGG, GNA12, HRG, PLAT, PROZ, SERPINC1, SERPINE2, SERPINF2, VTN	77	regulation of body fluid levels
GO:0051605	3.260e-02	2.066	8 C5, C8A, C8G, MASP1, MASP2, PSEN2, SERPINE2, VSIG4	27	protein maturation by peptide bond cleavage
GO:0044283	3.685e-02	14.23	27 ABCA1, ACER3, AGXT, AKAP12, AKR1D1, ATP8B1, AVPR1A, CDO1, CTH, CYP39A1, CYP7B1, ETNK2, FGF19, GARS, GCH1, GCLM, GNMT, GOT1, KMO, LIPC, NT5E, OTC, PAH, PCK1, PCK2, PYGL, RBP4	186	small molecule biosynthetic process
GO:0042632	3.764e-02	0.8417	5 ABCA1, LIPC, NPC1, NR5A2, SCARB1	11	cholesterol homeostasis
GO:0048708	3.764e-02	0.8417	5 BMP2, EGFR, F2, IL6ST, SERPINE2	11	astrocyte differentiation
GO:0055092	3.764e-02	0.8417	5 ABCA1, LIPC, NPC1, NR5A2, SCARB1	11	sterol homeostasis
GO:0046165	4.094e-02	1.683	7 ACER3, GNMT, GOT1, PCK1, PCK2, PYGL, RBP4	22	alcohol biosynthetic process
GO:0009069	4.352e-02	0.5357	4 AGXT, CDO1, CTH, GCLM	7	serine family amino acid metabolic process
GO:0043691	4.352e-02	0.5357	4 ABCA1, ABCA5, LIPC, SCARB1	7	reverse cholesterol transport
GO:0050999	4.352e-02	0.5357	4 ACVR2A, EGFR, GCH1, SCARB1	7	regulation of nitric-oxide synthase activity
GO:0019637	4.552e-02	5.586	14 ACSL5, CEPT1, CRLS1, ETNK2, GK5, GPLD1, INPP5E, LIPC, LPCAT3, PEMT, PIGK, PIGL, PIP5K1C, SERINC5	73	organophosphate metabolic process
GO:0008610	4.703e-02	10.94	22 ACER3, ACSL5, AKR1D1, AVPR1A, CEPT1, CRLS1, CYB5R2, CYP39A1, CYP7B1, ETNK2, FGF19, LIPC, LPCAT3, PCK1, PEMT, PEX7, PIGK, PIGL, SCARB1, SDR42E1, SERINC5, STARD5	143	lipid biosynthetic process
GO:0016053	4.964e-02	4.438	12 AGXT, AKR1D1, AVPR1A, CDO1, CTH, CYP39A1, CYP7B1, FGF19, GOT1, LIPC, OTC, PAH	58	organic acid biosynthetic process
GO:0046394	4.964e-02	4.438	12 AGXT, AKR1D1, AVPR1A, CDO1, CTH, CYP39A1, CYP7B1, FGF19, GOT1, LIPC, OTC, PAH	58	carboxylic acid biosynthetic process

Id	Pvalue	ExpCount	Count	Size	Term
GO:0044432	2.532e-07	17	44 ACER3, ACSL5, CEPT1, COL4A3BP, CREB3L3, CYP2R1, CYP39A1, CYP7B1, DDOST, DERL1, DERL3, EDEM3, EPHX1, ERP44, GJB1, H6PD, HM13, LPCAT3, LPIN2, LRAT, MFSD2A, MINPP1, MTDH, P4HA1, P4HTM, PACS2, PDIA5, PEMT, PIGK, PIGL, PSEN2, RNF103, SEC23A, SEC24D, SERINC5, SGPL1, SSR3, TLR3, TMED5, TMEM38A, TOR1B, TXNDC12, UBXN4, ZMPSTE24	227	endoplasmic reticulum part
GO:0071212	1.061e-06	17.89	44 ACER3, ACSL5, CEPT1, COL4A3BP, CREB3L3, CYP2R1, CYP39A1, CYP7B1, DDOST, DERL1, DERL3, EDEM3, EPHX1, ERP44, GJB1, H6PD, HM13, LPCAT3, LPIN2, LRAT, MFSD2A, MINPP1, MTDH, P4HA1, P4HTM, PACS2, PDIA5, PEMT, PIGK, PIGL, PSEN2, RNF103, SEC23A, SEC24D, SERINC5, SGPL1, SSR3, TLR3, TMED5, TMEM38A, TOR1B, TXNDC12, UBXN4, ZMPSTE24	239	subsynaptic reticulum
GO:0005783	6.602e-06	26.65	55 A1CF, ACER3, ACSL5, BDKRB1, CEPT1, CLN5, COL4A3BP, CREB3L3, CYP2R1, CYP39A1, CYP7B1, DDOST, DERL1, DERL3, EDEM3, EPHX1, ERP44, FAF2, GJB1, H6PD, HM13, KIFAP3, LPCAT3, LPIN2, LRAT, MFSD2A, MINPP1, MTDH, MTTP, NCSTN, NPC1, P4HA1, P4HTM, PACS2, PDE3B, PDIA5, PEMT, PIGK, PIGL, PLA2G12B, PSEN2, RNF103, SEC23A, SEC24D, SERINC5, SGPL1, SSR3, TLR3, TMED5, TMEM38A, TOR1B, TOR2A, TXNDC12, UBXN4, ZMPSTE24	356	endoplasmic reticulum
GO:0005789	2.259e-05	14.82	36 ACER3, ACSL5, CEPT1, COL4A3BP, CREB3L3, CYP2R1, CYP39A1, CYP7B1, DDOST, DERL1, DERL3, EPHX1, ERP44, GJB1, HM13, LPCAT3, LPIN2, LRAT, MFSD2A, MTDH, P4HTM, PEMT, PIGK, PIGL, PSEN2, RNF103, SEC23A, SEC24D, SERINC5, SGPL1, SSR3, TLR3, TMED5, TMEM38A, UBXN4, ZMPSTE24	198	endoplasmic reticulum membrane
GO:0042175	4.320e-05	15.27	36 ACER3, ACSL5, CEPT1, COL4A3BP, CREB3L3, CYP2R1, CYP39A1, CYP7B1, DDOST, DERL1, DERL3, EPHX1, ERP44, GJB1, HM13, LPCAT3, LPIN2, LRAT, MFSD2A, MTDH, P4HTM, PEMT, PIGK, PIGL, PSEN2, RNF103, SEC23A, SEC24D, SERINC5, SGPL1, SSR3, TLR3, TMED5, TMEM38A, UBXN4, ZMPSTE24	204	nuclear membrane-endoplasmic reticulum network
GO:0031091	1.533e-04	1.423	9 ALB, FGB, FGG, FN1, HGF, HRG, IGF1, SERPINE2, SERPINF2	19	platelet alpha granule
GO:0031093	1.758e-04	1.123	8 ALB, FGB, FGG, FN1, HGF, HRG, IGF1, SERPINF2	15	platelet alpha granule lumen
GO:0005576	1.775e-04	39.91	68 ADCK1, ADPGK, ALB, AMBP, BMP2, C5, C8A, C8G, CA6, COLEC10, CPB2, CREG1, DHRS11, EGFR, F10, F2, F9, FAM3C, FAM3D, FETUB, FGB, FGF19, FGFR1, FGG, FN1, GAS6, GGH, GPLD1, GPX7, HABP2, HGF, HHIP, HHIPL1, HPX, HRG, IDE, IGF1, IGFBP1, IHH, IL5RA, IL6ST, LAMB3, LEAP2, LECT2, LIPC, MASP1, MASP2, MMP13, PLA2G12B, PLAT, PM20D1, PRDX4, PROZ, PTPRG, QSOX1, RBP4, SERPINA10, SERPINC1, SERPINE2, SERPINF2, SNED1, SPP2, ST6GAL1, TOR2A, TWSG1, VLDLR, VTN, WNT9A	533	extracellular region
GO:0044444	1.861e-04	138.1	179 A1CF, AARS2, ABCA1, ABCA5, ABCD3, ACER3, ACOT12, ACSL5, ACSS3, ADCK1, AFMID, AGXT, AK2, AKAP12, AKR1D1, ALB, AMBRA1, AMDHD1, ANAPC2, ANAPC4, AP3M2, ARCN1, ARFGAP3, ARL3, AVPR1A, B4GALT5, BCKDHB, BDKRB1, BTRC, CABC1, CAPRIN2, CBY1, CCBL1, CDH1, CDO1, CEPT1, CLN5, CLPX, COL4A3BP, CREB3L3, CRLS1, CRYAB, CTBS, CYB5R2, CYP2R1, CYP39A1, CYP7B1, DDOST, DENND5A, DERL1, DERL3, DHDPSL, DHTKD1, DLST, EDEM3, EGFR, EPHX1, EPN2, ERP44, EVI5, FAF2, FAM3C, FAM82A2, FAM82B, FGB, FGG, FH, FN1, GARS, GBE1, GCH1, GCLM, GGCT, GGH, GJB1, GNMT, GOLIM4, GOT1, H6PD, HAL, HAO1, HEBP1, HGF, HM13, HRG, IDE, IGF1, IMPAD1, INPP5E, KIFAP3, KMO, LPCAT3, LPIN2, LRAT, MAN1A2, MAPK8IP3, ME2, MFSD2A, MINPP1, MMD, MRPL19, MRPS30, MTDH, MTFMT, MTMR2, MTPAP, MTTP, MYH10, NAGA, NCSTN, NPC1, NUDT12, NUDT19, OTC, P4HA1, P4HTM, PACS2, PANK1, PARD6A, PCK1, PCK2, PDE3B, PDIA5, PEMT, PEX11A, PEX7, PHKA2, PIGK, PIGL, PLA2G12B, PLAT, PRDX4, PSEN2, QSOX1, RAB30, RAB33B, RNF103, RNF144A, SEC23A, SEC24D, SERINC5, SERPINE2, SERPINF2, SFXN3, SGPL1, SH3RF1, SLC25A17, SLC25A40, SLC25A47, SLC2A2, SLC30A6, SLC30A7, SPIRE1, SS18, SSR3, ST6GAL1, STARD5, SUCLG1, SUPV3L1, TAT, TDO2, TLR3, TMED5, TMEM33, TMEM38A, TMEM55A, TMEM9, TOR1B, TOR2A, TTPA, TXNDC12, TXNRD1, UBXN4, UNC119, UPB1, USO1, USP20, WLS, ZMPSTE24	1844	cytoplasmic part
GO:0031983	2.975e-04	1.198	8 ALB, FGB, FGG, FN1, HGF, HRG, IGF1, SERPINF2	16	vesicle lumen
GO:0060205	2.975e-04	1.198	8 ALB, FGB, FGG, FN1, HGF, HRG, IGF1, SERPINF2	16	cytoplasmic membrane-bounded vesicle lumen
GO:0005615	3.572e-04	16.92	36 ALB, BMP2, C5, C8A, CPB2, EGFR, F2, FGB, FGG, FN1, GAS6, GGH, HABP2, HGF, HPX, IDE, IGF1, IGFBP1, IHH, IL5RA, IL6ST, LECT2, LIPC, MASP1, MMP13, PLAT, PRDX4, PTPRG, QSOX1, RBP4, SERPINC1, SERPINE2, SERPINF2, TWSG1, VLDLR, VTN	226	extracellular space
GO:0000267	5.653e-04	28.23	51 ABCA1, ABCB11, ABCC2, AMBP, ATP8B1, BDKRB1, BLMH, CRYAB, CYB5R2, CYP2R1, CYP39A1, CYP7B1, DDOST, DLST, EPHX1, F10, F2, FGB, FGFR1, GARS, GCLM, GLO1, GOT1, H6PD, HAL, IDE, IGF1R, LYVE1, MAN1A2, MMD, MPDZ, NCSTN, NT5E, PCK1, PCK2, PDE3B, PEMT, PSEN2, PYGL, SCARB1, SLC16A2, SLC2A2, SLC7A2, SSR3, STK39, TDO2, UNC119, USO1, VLDLR, WDR6, ZMPSTE24	377	cell fraction
GO:0031090	6.291e-03	50.46	74 ABCA5, ABCD3, ACER3, ACSL5, AK2, ARCN1, ARFGAP3, ARL3, B4GALT5, CEPT1, CLN5, CLPX, COL4A3BP, CREB3L3, CRLS1, CYP2R1, CYP39A1, CYP7B1, DDOST, DERL1, DERL3, EGFR, EPHX1, EPN2, ERP44, FAM82A2, GJB1, GOLIM4, HM13, INPP5E, KMO, LPCAT3, LPIN2, LRAT, MAN1A2, MAPK8IP3, MFSD2A, MMD, MRPL19, MTDH, MTMR2, NCSTN, NPC1, OTC, P4HTM, PEMT, PEX11A, PIGK, PIGL, PSEN2, QSOX1, RAB33B, RNF103, SEC23A, SEC24D, SERINC5, SFXN3, SGPL1, SLC25A17, SLC25A40, SLC25A47, SLC30A6, SSR3, ST6GAL1, SUCLG1, TLR3, TMED5, TMEM38A, TMEM55A, TMEM9, UBXN4, USO1, WLS, ZMPSTE24	674	organelle membrane
GO:0045239	9.018e-03	0.2246	3 BCKDHB, FH, SUCLG1	3	tricarboxylic acid cycle enzyme complex
GO:0005777	1.064e-02	2.471	9 ABCD3, AGXT, HAO1, IDE, NUDT12, NUDT19, PEX11A, PEX7, SLC25A17	33	peroxisome
GO:0042579	1.064e-02	2.471	9 ABCD3, AGXT, HAO1, IDE, NUDT12, NUDT19, PEX11A, PEX7, SLC25A17	33	microbody
GO:0005788	1.295e-02	2.546	9 EDEM3, ERP44, H6PD, MINPP1, P4HA1, PACS2, PDIA5, TOR1B, TXNDC12	34	endoplasmic reticulum lumen
GO:0005792	2.277e-02	5.091	13 AMBP, CYP2R1, CYP39A1, CYP7B1, DDOST, DLST, EPHX1, F10, H6PD, IGF1R, PDE3B, SSR3, USO1	68	microsome
GO:0044421	2.314e-02	23.96	39 ALB, BMP2, C5, C8A, CPB2, EGFR, F2, FGB, FGG, FN1, GAS6, GGH, GPLD1, HABP2, HGF, HPX, IDE, IGF1, IGFBP1, IHH, IL5RA, IL6ST, LAMB3, LECT2, LIPC, MASP1, MMP13, PLAT, PRDX4, PTPRG, QSOX1, RBP4, SERPINC1, SERPINE2, SERPINF2, TWSG1, VLDLR, VTN, WNT9A	320	extracellular region part
GO:0005579	2.605e-02	0.2995	3 C5, C8A, C8G	4	membrane attack complex
GO:0005626	3.132e-02	21.26	35 ABCA1, ABCB11, ABCC2, AMBP, ATP8B1, BDKRB1, CRYAB, CYP2R1, CYP39A1, CYP7B1, DDOST, DLST, EPHX1, F10, FGFR1, H6PD, IGF1R, LYVE1, MAN1A2, MMD, MPDZ, NCSTN, NT5E, PDE3B, PEMT, PSEN2, SCARB1, SLC16A2, SLC2A2, SLC7A2, SSR3, STK39, USO1, VLDLR, ZMPSTE24	284	insoluble fraction
GO:0042598	3.169e-02	5.316	13 AMBP, CYP2R1, CYP39A1, CYP7B1, DDOST, DLST, EPHX1, F10, H6PD, IGF1R, PDE3B, SSR3, USO1	71	vesicular fraction
GO:0005624	3.202e-02	20.52	34 ABCA1, ABCB11, ABCC2, AMBP, ATP8B1, BDKRB1, CYP2R1, CYP39A1, CYP7B1, DDOST, DLST, EPHX1, F10, FGFR1, H6PD, IGF1R, LYVE1, MAN1A2, MMD, MPDZ, NCSTN, NT5E, PDE3B, PEMT, PSEN2, SCARB1, SLC16A2, SLC2A2, SLC7A2, SSR3, STK39, USO1, VLDLR, ZMPSTE24	274	membrane fraction
GO:0012505	3.276e-02	40.28	58 ABCA5, ACER3, ACSL5, ARCN1, ARFGAP3, ARL3, B4GALT5, CEPT1, COL4A3BP, CREB3L3, CYP2R1, CYP39A1, CYP7B1, DDOST, DERL1, DERL3, EGFR, EPHX1, EPN2, ERP44, GJB1, GOLIM4, HM13, INPP5E, LPCAT3, LPIN2, LRAT, MAN1A2, MAPK8IP3, MFSD2A, MRPL19, MTDH, NPC1, OIT3, P4HTM, PEMT, PIGK, PIGL, PSEN2, QSOX1, RAB33B, RNF103, SEC23A, SEC24D, SERINC5, SGPL1, SLC2A9, SLC30A6, SSR3, ST6GAL1, TLR3, TMED5, TMEM38A, UBXN4, USO1, VLDLR, WLS, ZMPSTE24	538	endomembrane system
GO:0030141	3.287e-02	4.118	11 ALB, FGB, FGG, FN1, GARS, HGF, HRG, IGF1, PLAT, SERPINE2, SERPINF2	55	stored secretory granule
GO:0044425	3.800e-02	142.2	168 ABCA1, ABCA5, ABCB11, ABCC2, ABCD3, ACBD5, ACER3, ACSL5, ACVR2A, AP3M2, ARCN1, ATP8B1, AVPR1A, B4GALT5, BDKRB1, C19orf12, C1orf27, C5, C5orf43, C8A, C8G, C9orf91, CADM4, CD302, CD82, CDC42BPA, CDH1, CEPT1, CLDN1, CLN5, CNGA2, COL4A3BP, CREB3L3, CRLS1, CYP2R1, CYP39A1, CYP7B1, DDOST, DERL1, DERL3, DIRC2, DNAJC22, DPY19L3, EDAR, EGFR, EPHA1, EPHX1, EPN2, ERP44, ESR1, F10, FAM171A1, FAM69B, FAM82A2, FGB, FGFR1, FGG, FZD2, GJB1, GNB5, GOLIM4, GPHN, GPR132, GPR56, HHIP, HM13, IGF1R, IL5RA, IL6ST, IMPAD1, ITGA4, IYD, KCTD6, KIAA0090, KIAA0247, KIAA1432, KLB, KMO, LGR5, LPCAT3, LPIN2, LRAT, LRIG3, LRP11, LRRC15, LY75, LYVE1, MAN1A2, MARVELD3, MFSD2A, MMD, MPDZ, MPZL2, MTDH, NCSTN, NPC1, NT5E, OSCP1, P4HTM, PARD6A, PDE3B, PEMT, PEX11A, PIGK, PIGL, PSEN2, PTCH1, PTPRG, QSOX1, RASA3, RNF103, RNF144A, SCARB1, SDC2, SDR42E1, SEC23A, SEC24D, SERINC5, SERPINE2, SFXN3, SGPL1, SLC16A10, SLC16A2, SLC25A17, SLC25A40, SLC25A47, SLC2A2, SLC2A9, SLC30A1, SLC30A6, SLC30A7, SLC31A1, SLC37A1, SLC38A4, SLC39A8, SLC39A9, SLC45A3, SLC46A1, SLC7A2, SLC7A6, SSR3, ST6GAL1, STAB2, STK39, TLN2, TLR3, TMCO3, TMED5, TMEM135, TMEM14A, TMEM20, TMEM33, TMEM38A, TMEM41A, TMEM55A, TMEM9, TNMD, TRAM2, TRPM7, TXNDC15, UBXN4, VLDLR, VSIG4, VTN, WLS, XCR1, XKR9, ZMPSTE24	1899	membrane part

Id	Pvalue	ExpCount	Count	Size	Term
GO:0003824	1.740e-04	132.3	175 A1CF, AARS2, ABCA1, ABCA5, ABCB11, ABCC2, ABCD3, ACER3, ACOT12, ACSL5, ACSS3, ACVR2A, ADCK1, ADPGK, AFMID, AGXT, AK2, AKR1D1, AMDHD1, ANAPC2, ANAPC4, ASPG, ATP8B1, B4GALT5, BCKDHB, BLMH, BMP2, BTRC, C1orf27, CA6, CABC1, CCBL1, CDC42BPA, CDO1, CEPT1, CLPX, COL4A3BP, CPB2, CRLS1, CTBS, CTH, CYB5R2, CYP2R1, CYP39A1, CYP7B1, DDOST, DHDPSL, DHRS11, DHTKD1, DLST, EDEM3, EGFR, EPHA1, EPHX1, ERP44, ETNK2, F10, F2, F9, FBXO4, FGFR1, FH, GAR1, GARS, GBE1, GCH1, GCLM, GGCT, GGH, GK5, GLO1, GMPR, GNA12, GNB5, GNMT, GOT1, GPHN, GPLD1, GPX7, H6PD, HABP2, HAL, HAO1, HGD, HGF, HHIP, HHIPL1, HM13, HYI, IDE, IGF1R, IHH, IMPAD1, INPP5E, IYD, KLB, KMO, KSR1, LIPC, LPCAT3, LPIN2, LRAT, MAN1A2, MAP2K5, MASP1, MASP2, MAT1A, ME2, MINPP1, MMP13, MTAP, MTFMT, MTMR2, MTPAP, MYH10, NAGA, NCSTN, NT5E, NUDT12, NUDT19, OTC, P4HA1, P4HTM, PAFAH1B2, PAFAH2, PAH, PANK1, PARP6, PCK1, PCK2, PDE3B, PDIA5, PEMT, PHKA2, PIAS1, PIGK, PIGL, PIP5K1C, PLA2G12B, PLAT, PM20D1, POLR2C, PPEF2, PRDX4, PROZ, PSEN2, PTPRG, PYGL, QSOX1, RAB30, RNF103, RNF144A, SDR42E1, SGPL1, SH3RF1, ST6GAL1, STAB2, STK39, SUCLG1, SUPV3L1, TAT, TDO2, TMEM55A, TOR1B, TOR2A, TRPM7, TWISTNB, TXNDC12, TXNRD1, UPB1, USP20, XRCC6BP1, YTHDC2, ZC3H12D, ZMPSTE24	1790	catalytic activity
GO:0019842	2.095e-04	4.066	16 AGXT, ALB, C8G, CCBL1, CTH, DHTKD1, GNMT, GOT1, P4HA1, P4HTM, PYGL, RBP4, SGPL1, SLC46A1, TAT, TTPA	55	vitamin binding
GO:0031406	1.844e-03	3.918	14 ACBD5, AGXT, ALB, GNMT, GOT1, OTC, P4HA1, P4HTM, PAH, PCK1, PYGL, SLC46A1, TAT, TDO2	53	carboxylic acid binding
GO:0016709	2.569e-03	0.2957	4 CYP2R1, CYP39A1, CYP7B1, KMO	4	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
GO:0005506	4.880e-03	3.327	12 AMBP, CDO1, CYP2R1, CYP39A1, CYP7B1, HEBP1, NT5E, P4HA1, P4HTM, PAH, PPEF2, TDO2	45	iron ion binding
GO:0030170	5.063e-03	1.552	8 AGXT, ALB, CCBL1, CTH, GOT1, PYGL, SGPL1, TAT	21	pyridoxal phosphate binding
GO:0070279	5.063e-03	1.552	8 AGXT, ALB, CCBL1, CTH, GOT1, PYGL, SGPL1, TAT	21	vitamin B6 binding
GO:0016491	5.574e-03	15.15	31 AKR1D1, BCKDHB, BMP2, C1orf27, CDO1, CYB5R2, CYP2R1, CYP39A1, CYP7B1, DHRS11, DHTKD1, GCLM, GMPR, GPX7, H6PD, HAO1, HGD, IYD, KMO, ME2, P4HA1, P4HTM, PAH, PDIA5, PRDX4, QSOX1, SDR42E1, STAB2, TDO2, TXNDC12, TXNRD1	205	oxidoreductase activity
GO:0048037	1.520e-02	6.136	16 ACBD5, AGXT, ALB, CCBL1, CTH, DHTKD1, GOT1, H6PD, HAO1, KMO, ME2, PAH, PYGL, SGPL1, TAT, TXNRD1	83	cofactor binding
GO:0034185	1.841e-02	0.4436	4 ABCA1, LIPC, SCARB1, VLDLR	6	apolipoprotein binding
GO:0016831	1.856e-02	0.7393	5 BCKDHB, GOT1, PCK1, PCK2, SGPL1	10	carboxy-lyase activity
GO:0003847	1.872e-02	0.2218	3 ASPG, PAFAH1B2, PAFAH2	3	1-alkyl-2-acetylglycerophosphocholine esterase activity
GO:0004866	2.528e-02	2.513	9 AMBP, C5, FETUB, HRG, SERPINA10, SERPINC1, SERPINE2, SERPINF2, SPP2	34	endopeptidase inhibitor activity
GO:0016829	2.703e-02	4.731	13 BCKDHB, CA6, CCBL1, CTH, DHDPSL, FH, GLO1, GOT1, HAL, PCK1, PCK2, SGPL1, TAT	64	lyase activity
GO:0061135	3.015e-02	2.587	9 AMBP, C5, FETUB, HRG, SERPINA10, SERPINC1, SERPINE2, SERPINF2, SPP2	35	endopeptidase regulator activity
GO:0004553	3.415e-02	2.144	8 ACER3, CTBS, EDEM3, GBE1, KLB, MAN1A2, NAGA, PHKA2	29	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0061134	3.460e-02	3.179	10 AMBP, C5, CLPX, FETUB, HRG, SERPINA10, SERPINC1, SERPINE2, SERPINF2, SPP2	43	peptidase regulator activity
GO:0004252	3.540e-02	2.661	9 F10, F2, F9, HABP2, HGF, MASP1, MASP2, PLAT, PROZ	36	serine-type endopeptidase activity
GO:0030414	3.540e-02	2.661	9 AMBP, C5, FETUB, HRG, SERPINA10, SERPINC1, SERPINE2, SERPINF2, SPP2	36	peptidase inhibitor activity

Id	Pvalue	ExpCount	Count	Size	Term
04610	1.653e-08	2.166	15 BDKRB1, C5, C8A, C8G, CPB2, F10, F2, F9, FGB, FGG, MASP1, MASP2, PLAT, SERPINC1, SERPINF2	21	Complement and coagulation cascades
00270	1.699e-02	1.134	6 CDO1, CTH, GOT1, MAT1A, MTAP, TAT	11	Cysteine and methionine metabolism
01100	2.563e-02	36.41	54 ACSL5, ACSS3, ADPGK, AFMID, AGXT, AK2, AKR1D1, AMDHD1, BCKDHB, CDO1, CEPT1, CRLS1, CTH, DDOST, DLST, ETNK2, FH, GBE1, GCH1, GCLM, GOT1, H6PD, HAL, HAO1, HGD, HYI, INPP5E, KMO, LIPC, MAN1A2, MAT1A, MTAP, MTMR2, NT5E, OTC, P4HA1, PAFAH1B2, PAFAH2, PAH, PANK1, PCK1, PCK2, PEMT, PIGK, PIGL, PIP5K1C, PLA2G12B, POLR2C, SGPL1, ST6GAL1, SUCLG1, TAT, TDO2, UPB1	353	Metabolic pathways
00120	3.995e-02	0.3094	3 AKR1D1, CYP39A1, CYP7B1	3	Primary bile acid biosynthesis
00400	3.995e-02	0.3094	3 GOT1, PAH, TAT	3	Phenylalanine, tyrosine and tryptophan biosynthesis

No enriched terms

No enriched terms

Entrez genes

A1CFAPOBEC1 complementation factor (ENSG00000148584), score: 0.49 AARS2alanyl-tRNA synthetase 2, mitochondrial (putative) (ENSG00000124608), score: 0.65 ABCA1ATP-binding cassette, sub-family A (ABC1), member 1 (ENSG00000165029), score: 0.74 ABCA5ATP-binding cassette, sub-family A (ABC1), member 5 (ENSG00000154265), score: -0.68 ABCB11ATP-binding cassette, sub-family B (MDR/TAP), member 11 (ENSG00000073734), score: 0.57 ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ENSG00000023839), score: 0.5 ABCD3ATP-binding cassette, sub-family D (ALD), member 3 (ENSG00000117528), score: 0.59 ACBD5acyl-CoA binding domain containing 5 (ENSG00000107897), score: 0.53 ACER3alkaline ceramidase 3 (ENSG00000078124), score: 0.8 ACOT12acyl-CoA thioesterase 12 (ENSG00000172497), score: 0.72 ACSL5acyl-CoA synthetase long-chain family member 5 (ENSG00000197142), score: 0.65 ACSS3acyl-CoA synthetase short-chain family member 3 (ENSG00000111058), score: 0.58 ACVR2Aactivin A receptor, type IIA (ENSG00000121989), score: 0.57 ADCK1aarF domain containing kinase 1 (ENSG00000063761), score: -0.72 ADPGKADP-dependent glucokinase (ENSG00000159322), score: 0.6 AFMIDarylformamidase (ENSG00000183077), score: 0.52 AGXTalanine-glyoxylate aminotransferase (ENSG00000172482), score: 0.66 AK2adenylate kinase 2 (ENSG00000004455), score: 0.69 AKAP12A kinase (PRKA) anchor protein 12 (ENSG00000131016), score: -0.63 AKR1D1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (ENSG00000122787), score: 0.75 ALBalbumin (ENSG00000163631), score: 0.66 AMBPalpha-1-microglobulin/bikunin precursor (ENSG00000106927), score: 0.6 AMBRA1autophagy/beclin-1 regulator 1 (ENSG00000110497), score: 0.63 AMDHD1amidohydrolase domain containing 1 (ENSG00000139344), score: 0.68 ANAPC2anaphase promoting complex subunit 2 (ENSG00000176248), score: -0.62 ANAPC4anaphase promoting complex subunit 4 (ENSG00000053900), score: -0.58 AP3M2adaptor-related protein complex 3, mu 2 subunit (ENSG00000070718), score: -0.57 APBB2amyloid beta (A4) precursor protein-binding, family B, member 2 (ENSG00000163697), score: -0.66 ARCN1archain 1 (ENSG00000095139), score: 0.55 ARFGAP3ADP-ribosylation factor GTPase activating protein 3 (ENSG00000242247), score: 0.71 ARHGEF38Rho guanine nucleotide exchange factor (GEF) 38 (ENSG00000138784), score: 0.66 ARL14ADP-ribosylation factor-like 14 (ENSG00000179674), score: 0.97 ARL3ADP-ribosylation factor-like 3 (ENSG00000138175), score: -0.56 ARL5BADP-ribosylation factor-like 5B (ENSG00000165997), score: 0.7 ASPGasparaginase homolog (S. cerevisiae) (ENSG00000166183), score: 0.59 ATMINATM interactor (ENSG00000166454), score: -0.65 ATP8B1ATPase, aminophospholipid transporter, class I, type 8B, member 1 (ENSG00000081923), score: 0.61 AVPR1Aarginine vasopressin receptor 1A (ENSG00000166148), score: 0.82 B4GALT5UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (ENSG00000158470), score: -0.6 BAT2L1HLA-B associated transcript 2-like 1 (ENSG00000130723), score: -0.62 BCKDHBbranched chain keto acid dehydrogenase E1, beta polypeptide (ENSG00000083123), score: 0.56 BDKRB1bradykinin receptor B1 (ENSG00000100739), score: 0.51 BLMHbleomycin hydrolase (ENSG00000108578), score: 0.59 BMP2bone morphogenetic protein 2 (ENSG00000125845), score: 0.67 BTRCbeta-transducin repeat containing (ENSG00000166167), score: -0.66 C19orf12chromosome 19 open reading frame 12 (ENSG00000131943), score: -0.57 C1orf27chromosome 1 open reading frame 27 (ENSG00000157181), score: 0.5 C5complement component 5 (ENSG00000106804), score: 0.71 C5orf43chromosome 5 open reading frame 43 (ENSG00000188725), score: 0.51 C8Acomplement component 8, alpha polypeptide (ENSG00000157131), score: 0.65 C8Gcomplement component 8, gamma polypeptide (ENSG00000176919), score: 0.52 C9orf91chromosome 9 open reading frame 91 (ENSG00000157693), score: 0.5 CA6carbonic anhydrase VI (ENSG00000131686), score: 0.76 CABC1chaperone, ABC1 activity of bc1 complex homolog (S. pombe) (ENSG00000163050), score: 0.49 CADM4cell adhesion molecule 4 (ENSG00000105767), score: -0.6 CAMSAP1calmodulin regulated spectrin-associated protein 1 (ENSG00000130559), score: -0.56 CAPRIN2caprin family member 2 (ENSG00000110888), score: -0.65 CBY1chibby homolog 1 (Drosophila) (ENSG00000100211), score: -0.73 CCBL1cysteine conjugate-beta lyase, cytoplasmic (ENSG00000171097), score: 0.54 CCDC92coiled-coil domain containing 92 (ENSG00000119242), score: -0.63 CD82CD82 molecule (ENSG00000085117), score: 0.67 CDC42BPACDC42 binding protein kinase alpha (DMPK-like) (ENSG00000143776), score: -0.65 CDH1cadherin 1, type 1, E-cadherin (epithelial) (ENSG00000039068), score: 0.49 CDO1cysteine dioxygenase, type I (ENSG00000129596), score: 0.59 CEPT1choline/ethanolamine phosphotransferase 1 (ENSG00000134255), score: 0.68 CIAO1cytosolic iron-sulfur protein assembly 1 (ENSG00000144021), score: 0.52 CISHcytokine inducible SH2-containing protein (ENSG00000114737), score: 0.49 CLDN1claudin 1 (ENSG00000163347), score: 0.63 CLN5ceroid-lipofuscinosis, neuronal 5 (ENSG00000102805), score: 0.52 CLPXClpX caseinolytic peptidase X homolog (E. coli) (ENSG00000166855), score: 0.59 CNGA2cyclic nucleotide gated channel alpha 2 (ENSG00000183862), score: 0.49 COL4A3BPcollagen, type IV, alpha 3 (Goodpasture antigen) binding protein (ENSG00000113163), score: 0.56 COLEC10collectin sub-family member 10 (C-type lectin) (ENSG00000184374), score: 0.55 CPB2carboxypeptidase B2 (plasma) (ENSG00000080618), score: 0.64 CREB3L3cAMP responsive element binding protein 3-like 3 (ENSG00000060566), score: 0.54 CREG1cellular repressor of E1A-stimulated genes 1 (ENSG00000143162), score: 0.5 CRLS1cardiolipin synthase 1 (ENSG00000088766), score: 0.53 CRYABcrystallin, alpha B (ENSG00000109846), score: -0.58 CTBSchitobiase, di-N-acetyl- (ENSG00000117151), score: 0.8 CTHcystathionase (cystathionine gamma-lyase) (ENSG00000116761), score: 0.62 CUEDC2CUE domain containing 2 (ENSG00000107874), score: -0.77 CXXC5CXXC finger 5 (ENSG00000171604), score: -0.61 CYB5R2cytochrome b5 reductase 2 (ENSG00000166394), score: 0.61 CYP2R1cytochrome P450, family 2, subfamily R, polypeptide 1 (ENSG00000186104), score: 0.59 CYP39A1cytochrome P450, family 39, subfamily A, polypeptide 1 (ENSG00000146233), score: 0.89 CYP7B1cytochrome P450, family 7, subfamily B, polypeptide 1 (ENSG00000172817), score: 0.56 DDOSTdolichyl-diphosphooligosaccharide--protein glycosyltransferase (ENSG00000244038), score: 0.52 DENND1BDENN/MADD domain containing 1B (ENSG00000213047), score: 0.53 DENND5ADENN/MADD domain containing 5A (ENSG00000184014), score: -0.65 DERL1Der1-like domain family, member 1 (ENSG00000136986), score: 0.65 DERL3Der1-like domain family, member 3 (ENSG00000099958), score: 0.49 DHDPSLdihydrodipicolinate synthase-like, mitochondrial (ENSG00000241935), score: 0.51 DHRS11dehydrogenase/reductase (SDR family) member 11 (ENSG00000108272), score: -0.61 DHTKD1dehydrogenase E1 and transketolase domain containing 1 (ENSG00000181192), score: 0.76 DIRC2disrupted in renal carcinoma 2 (ENSG00000138463), score: 0.55 DLSTdihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (ENSG00000119689), score: 0.48 DNAJC22DnaJ (Hsp40) homolog, subfamily C, member 22 (ENSG00000178401), score: 0.52 DPY19L3dpy-19-like 3 (C. elegans) (ENSG00000178904), score: 0.55 EDARectodysplasin A receptor (ENSG00000135960), score: 0.48 EDEM3ER degradation enhancer, mannosidase alpha-like 3 (ENSG00000116406), score: 0.68 EGFRepidermal growth factor receptor (ENSG00000146648), score: 0.6 EPHA1EPH receptor A1 (ENSG00000146904), score: 0.64 EPHX1epoxide hydrolase 1, microsomal (xenobiotic) (ENSG00000143819), score: 0.52 EPN2epsin 2 (ENSG00000072134), score: -0.61 ERP44endoplasmic reticulum protein 44 (ENSG00000023318), score: 0.48 ESR1estrogen receptor 1 (ENSG00000091831), score: 0.61 ESRP2epithelial splicing regulatory protein 2 (ENSG00000103067), score: 0.53 ETNK2ethanolamine kinase 2 (ENSG00000143845), score: 0.56 EVI5ecotropic viral integration site 5 (ENSG00000067208), score: 0.5 F10coagulation factor X (ENSG00000126218), score: 0.49 F2coagulation factor II (thrombin) (ENSG00000180210), score: 0.62 F9coagulation factor IX (ENSG00000101981), score: 0.74 FAF2Fas associated factor family member 2 (ENSG00000113194), score: 0.56 FAM171A1family with sequence similarity 171, member A1 (ENSG00000148468), score: -0.63 FAM3Cfamily with sequence similarity 3, member C (ENSG00000196937), score: -0.6 FAM3Dfamily with sequence similarity 3, member D (ENSG00000198643), score: 0.55 FAM69Bfamily with sequence similarity 69, member B (ENSG00000165716), score: -0.61 FAM82A2family with sequence similarity 82, member A2 (ENSG00000137824), score: 0.56 FAM82Bfamily with sequence similarity 82, member B (ENSG00000176623), score: 0.53 FBXO4F-box protein 4 (ENSG00000151876), score: 0.52 FETUBfetuin B (ENSG00000090512), score: 0.9 FGBfibrinogen beta chain (ENSG00000171564), score: 0.57 FGF19fibroblast growth factor 19 (ENSG00000162344), score: 0.59 FGFR1fibroblast growth factor receptor 1 (ENSG00000077782), score: -0.62 FGGfibrinogen gamma chain (ENSG00000171557), score: 0.61 FHfumarate hydratase (ENSG00000091483), score: 0.47 FN1fibronectin 1 (ENSG00000115414), score: 0.67 FZD2frizzled homolog 2 (Drosophila) (ENSG00000180340), score: 0.57 GAR1GAR1 ribonucleoprotein homolog (yeast) (ENSG00000109534), score: 0.62 GARSglycyl-tRNA synthetase (ENSG00000106105), score: 0.5 GAS2growth arrest-specific 2 (ENSG00000148935), score: 0.56 GAS6growth arrest-specific 6 (ENSG00000183087), score: -0.87 GBE1glucan (1,4-alpha-), branching enzyme 1 (ENSG00000114480), score: 0.53 GCH1GTP cyclohydrolase 1 (ENSG00000131979), score: 0.58 GCLMglutamate-cysteine ligase, modifier subunit (ENSG00000023909), score: 0.69 GGCTgamma-glutamylcyclotransferase (ENSG00000006625), score: 0.53 GGHgamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (ENSG00000137563), score: 0.47 GJB1gap junction protein, beta 1, 32kDa (ENSG00000169562), score: 0.48 GK5glycerol kinase 5 (putative) (ENSG00000175066), score: 0.74 GLO1glyoxalase I (ENSG00000124767), score: 0.55 GMPRguanosine monophosphate reductase (ENSG00000137198), score: -0.61 GNA12guanine nucleotide binding protein (G protein) alpha 12 (ENSG00000146535), score: -0.6 GNB5guanine nucleotide binding protein (G protein), beta 5 (ENSG00000069966), score: -0.58 GNMTglycine N-methyltransferase (ENSG00000124713), score: 0.67 GOLIM4golgi integral membrane protein 4 (ENSG00000173905), score: 0.51 GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) (ENSG00000120053), score: 0.64 GPHNgephyrin (ENSG00000171723), score: 0.57 GPLD1glycosylphosphatidylinositol specific phospholipase D1 (ENSG00000112293), score: 0.64 GPR132G protein-coupled receptor 132 (ENSG00000183484), score: 0.48 GPR56G protein-coupled receptor 56 (ENSG00000205336), score: -0.61 GPX7glutathione peroxidase 7 (ENSG00000116157), score: 0.6 GTF2E1general transcription factor IIE, polypeptide 1, alpha 56kDa (ENSG00000153767), score: 0.53 GTPBP8GTP-binding protein 8 (putative) (ENSG00000163607), score: 0.48 H6PDhexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) (ENSG00000049239), score: 0.51 HABP2hyaluronan binding protein 2 (ENSG00000148702), score: 0.48 HALhistidine ammonia-lyase (ENSG00000084110), score: 0.86 HAO1hydroxyacid oxidase (glycolate oxidase) 1 (ENSG00000101323), score: 0.61 HEBP1heme binding protein 1 (ENSG00000013583), score: 0.65 HGDhomogentisate 1,2-dioxygenase (ENSG00000113924), score: 0.52 HGFhepatocyte growth factor (hepapoietin A; scatter factor) (ENSG00000019991), score: 0.67 HHIPhedgehog interacting protein (ENSG00000164161), score: 0.56 HHIPL1HHIP-like 1 (ENSG00000182218), score: 0.5 HM13histocompatibility (minor) 13 (ENSG00000101294), score: 0.65 HMGXB4HMG box domain containing 4 (ENSG00000100281), score: 0.55 HPXhemopexin (ENSG00000110169), score: 0.64 HRGhistidine-rich glycoprotein (ENSG00000113905), score: 0.56 HYIhydroxypyruvate isomerase (putative) (ENSG00000178922), score: 0.52 IBTKinhibitor of Bruton agammaglobulinemia tyrosine kinase (ENSG00000005700), score: 0.51 IDEinsulin-degrading enzyme (ENSG00000119912), score: 0.48 IGF1insulin-like growth factor 1 (somatomedin C) (ENSG00000017427), score: 0.53 IGF1Rinsulin-like growth factor 1 receptor (ENSG00000140443), score: -0.65 IGFBP1insulin-like growth factor binding protein 1 (ENSG00000146678), score: 0.71 IHHIndian hedgehog (ENSG00000163501), score: 0.53 IL5RAinterleukin 5 receptor, alpha (ENSG00000091181), score: 0.56 IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor) (ENSG00000134352), score: 0.57 IMPAD1inositol monophosphatase domain containing 1 (ENSG00000104331), score: -0.62 INPP5Einositol polyphosphate-5-phosphatase, 72 kDa (ENSG00000148384), score: -0.56 ITGA4integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ENSG00000115232), score: 0.7 IYDiodotyrosine deiodinase (ENSG00000009765), score: 0.79 KCTD6potassium channel tetramerisation domain containing 6 (ENSG00000168301), score: 0.53 KIAA0090KIAA0090 (ENSG00000127463), score: 0.54 KIAA0247KIAA0247 (ENSG00000100647), score: 0.52 KIAA0664KIAA0664 (ENSG00000132361), score: 0.52 KIAA1432KIAA1432 (ENSG00000107036), score: 0.66 KIFAP3kinesin-associated protein 3 (ENSG00000075945), score: -0.58 KLBklotho beta (ENSG00000134962), score: 0.48 KLHDC8Bkelch domain containing 8B (ENSG00000185909), score: -0.66 KLHL5kelch-like 5 (Drosophila) (ENSG00000109790), score: -0.99 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (ENSG00000117009), score: 0.57 KSR1kinase suppressor of ras 1 (ENSG00000141068), score: -0.57 LAMB3laminin, beta 3 (ENSG00000196878), score: 0.51 LEAP2liver expressed antimicrobial peptide 2 (ENSG00000164406), score: 0.6 LECT2leukocyte cell-derived chemotaxin 2 (ENSG00000145826), score: 0.9 LGR5leucine-rich repeat-containing G protein-coupled receptor 5 (ENSG00000139292), score: 0.54 LIPClipase, hepatic (ENSG00000166035), score: 0.55 LOC100292021similar to thioredoxin peroxidase (ENSG00000123131), score: 0.73 LPCAT3lysophosphatidylcholine acyltransferase 3 (ENSG00000111684), score: 0.51 LPIN2lipin 2 (ENSG00000101577), score: 0.59 LRATlecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) (ENSG00000121207), score: 0.66 LRIG3leucine-rich repeats and immunoglobulin-like domains 3 (ENSG00000139263), score: 0.6 LRP11low density lipoprotein receptor-related protein 11 (ENSG00000120256), score: -0.66 LRRC15leucine rich repeat containing 15 (ENSG00000172061), score: 0.85 LRRC31leucine rich repeat containing 31 (ENSG00000114248), score: 0.62 LRRC58leucine rich repeat containing 58 (ENSG00000163428), score: 0.54 LY75lymphocyte antigen 75 (ENSG00000054219), score: 0.75 LYVE1lymphatic vessel endothelial hyaluronan receptor 1 (ENSG00000133800), score: 0.54 MAN1A2mannosidase, alpha, class 1A, member 2 (ENSG00000198162), score: 0.58 MAP2K5mitogen-activated protein kinase kinase 5 (ENSG00000137764), score: -0.59 MAPK8IP3mitogen-activated protein kinase 8 interacting protein 3 (ENSG00000138834), score: -0.57 MARVELD3MARVEL domain containing 3 (ENSG00000140832), score: 0.51 MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (ENSG00000127241), score: 0.53 MASP2mannan-binding lectin serine peptidase 2 (ENSG00000009724), score: 0.6 MAT1Amethionine adenosyltransferase I, alpha (ENSG00000151224), score: 0.67 MBNL2muscleblind-like 2 (Drosophila) (ENSG00000139793), score: -0.7 ME2malic enzyme 2, NAD(+)-dependent, mitochondrial (ENSG00000082212), score: -0.63 MFSD2Amajor facilitator superfamily domain containing 2A (ENSG00000168389), score: 0.54 MINPP1multiple inositol-polyphosphate phosphatase 1 (ENSG00000107789), score: 0.5 MKLN1muskelin 1, intracellular mediator containing kelch motifs (ENSG00000128585), score: 0.76 MMDmonocyte to macrophage differentiation-associated (ENSG00000108960), score: 0.48 MMP13matrix metallopeptidase 13 (collagenase 3) (ENSG00000137745), score: 0.65 MPDZmultiple PDZ domain protein (ENSG00000107186), score: -0.59 MPZL2myelin protein zero-like 2 (ENSG00000149573), score: 0.54 MRPL19mitochondrial ribosomal protein L19 (ENSG00000115364), score: 0.48 MRPS30mitochondrial ribosomal protein S30 (ENSG00000112996), score: 0.6 MTAPmethylthioadenosine phosphorylase (ENSG00000099810), score: 0.64 MTDHmetadherin (ENSG00000147649), score: 0.47 MTFMTmitochondrial methionyl-tRNA formyltransferase (ENSG00000103707), score: 0.58 MTMR2myotubularin related protein 2 (ENSG00000087053), score: -0.73 MTPAPmitochondrial poly(A) polymerase (ENSG00000107951), score: 0.58 MTTPmicrosomal triglyceride transfer protein (ENSG00000138823), score: 0.66 MYH10myosin, heavy chain 10, non-muscle (ENSG00000133026), score: -0.59 NAGAN-acetylgalactosaminidase, alpha- (ENSG00000198951), score: 0.65 NCSTNnicastrin (ENSG00000162736), score: 0.58 NOP58NOP58 ribonucleoprotein homolog (yeast) (ENSG00000055044), score: 0.86 NPC1Niemann-Pick disease, type C1 (ENSG00000141458), score: 0.7 NR5A2nuclear receptor subfamily 5, group A, member 2 (ENSG00000116833), score: 0.61 NRBF2nuclear receptor binding factor 2 (ENSG00000148572), score: 0.62 NT5E5'-nucleotidase, ecto (CD73) (ENSG00000135318), score: 0.55 NUDT12nudix (nucleoside diphosphate linked moiety X)-type motif 12 (ENSG00000112874), score: 0.6 NUDT19nudix (nucleoside diphosphate linked moiety X)-type motif 19 (ENSG00000213965), score: 0.56 OIT3oncoprotein induced transcript 3 (ENSG00000138315), score: 0.61 ONECUT1one cut homeobox 1 (ENSG00000169856), score: 0.63 OSBPL2oxysterol binding protein-like 2 (ENSG00000130703), score: -0.57 OSCP1organic solute carrier partner 1 (ENSG00000116885), score: -0.56 OTCornithine carbamoyltransferase (ENSG00000036473), score: 0.85 P4HA1prolyl 4-hydroxylase, alpha polypeptide I (ENSG00000122884), score: 0.67 P4HTMprolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (ENSG00000178467), score: -0.75 PACS2phosphofurin acidic cluster sorting protein 2 (ENSG00000179364), score: -0.67 PAFAH1B2platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) (ENSG00000168092), score: -0.64 PAFAH2platelet-activating factor acetylhydrolase 2, 40kDa (ENSG00000158006), score: 0.62 PAHphenylalanine hydroxylase (ENSG00000171759), score: 0.53 PANK1pantothenate kinase 1 (ENSG00000152782), score: 0.6 PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans) (ENSG00000102981), score: -0.62 PARP6poly (ADP-ribose) polymerase family, member 6 (ENSG00000137817), score: -0.59 PCK1phosphoenolpyruvate carboxykinase 1 (soluble) (ENSG00000124253), score: 0.49 PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial) (ENSG00000100889), score: 0.66 PDE3Bphosphodiesterase 3B, cGMP-inhibited (ENSG00000152270), score: 0.55 PDIA5protein disulfide isomerase family A, member 5 (ENSG00000065485), score: 0.49 PEMTphosphatidylethanolamine N-methyltransferase (ENSG00000133027), score: 0.58 PEX11Aperoxisomal biogenesis factor 11 alpha (ENSG00000166821), score: 0.71 PEX7peroxisomal biogenesis factor 7 (ENSG00000112357), score: 0.55 PHKA2phosphorylase kinase, alpha 2 (liver) (ENSG00000044446), score: 0.49 PHLDB1pleckstrin homology-like domain, family B, member 1 (ENSG00000019144), score: -0.58 PIAS1protein inhibitor of activated STAT, 1 (ENSG00000033800), score: -0.59 PIGKphosphatidylinositol glycan anchor biosynthesis, class K (ENSG00000142892), score: 0.49 PIGLphosphatidylinositol glycan anchor biosynthesis, class L (ENSG00000108474), score: 0.48 PIP5K1Cphosphatidylinositol-4-phosphate 5-kinase, type I, gamma (ENSG00000186111), score: -0.64 PLA2G12Bphospholipase A2, group XIIB (ENSG00000138308), score: 0.64 PLATplasminogen activator, tissue (ENSG00000104368), score: -0.58 PM20D1peptidase M20 domain containing 1 (ENSG00000162877), score: 0.59 POLR2Cpolymerase (RNA) II (DNA directed) polypeptide C, 33kDa (ENSG00000102978), score: -0.65 PPEF2protein phosphatase, EF-hand calcium binding domain 2 (ENSG00000156194), score: 0.73 PROZprotein Z, vitamin K-dependent plasma glycoprotein (ENSG00000126231), score: 0.62 PSEN2presenilin 2 (Alzheimer disease 4) (ENSG00000143801), score: 0.57 PTCH1patched 1 (ENSG00000185920), score: -0.59 PTPRGprotein tyrosine phosphatase, receptor type, G (ENSG00000144724), score: 0.66 PYGLphosphorylase, glycogen, liver (ENSG00000100504), score: 0.55 QSOX1quiescin Q6 sulfhydryl oxidase 1 (ENSG00000116260), score: -0.7 R3HCC1R3H domain and coiled-coil containing 1 (ENSG00000104679), score: -0.56 RAB30RAB30, member RAS oncogene family (ENSG00000137502), score: 0.52 RAB33BRAB33B, member RAS oncogene family (ENSG00000172007), score: 0.61 RASA3RAS p21 protein activator 3 (ENSG00000185989), score: -0.59 RASSF6Ras association (RalGDS/AF-6) domain family member 6 (ENSG00000169435), score: 0.49 RBP4retinol binding protein 4, plasma (ENSG00000138207), score: 0.62 RGS18regulator of G-protein signaling 18 (ENSG00000150681), score: 0.79 RGS2regulator of G-protein signaling 2, 24kDa (ENSG00000116741), score: -0.77 RNF103ring finger protein 103 (ENSG00000239305), score: 0.54 RNF144Aring finger protein 144A (ENSG00000151692), score: -0.59 SCARB1scavenger receptor class B, member 1 (ENSG00000073060), score: 0.64 SDC2syndecan 2 (ENSG00000169439), score: 0.62 SDR42E1short chain dehydrogenase/reductase family 42E, member 1 (ENSG00000184860), score: 0.5 SEBOXSEBOX homeobox (ENSG00000109072), score: 0.57 SEC23ASec23 homolog A (S. cerevisiae) (ENSG00000100934), score: 0.55 SEC24DSEC24 family, member D (S. cerevisiae) (ENSG00000150961), score: 0.48 SERINC5serine incorporator 5 (ENSG00000164300), score: 0.51 SERPINA10serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 (ENSG00000140093), score: 0.67 SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 1 (ENSG00000117601), score: 0.67 SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (ENSG00000135919), score: -0.59 SERPINF2serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (ENSG00000167711), score: 0.55 SETBP1SET binding protein 1 (ENSG00000152217), score: -0.66 SFXN3sideroflexin 3 (ENSG00000107819), score: -0.61 SGPL1sphingosine-1-phosphate lyase 1 (ENSG00000166224), score: 0.6 SGSM2small G protein signaling modulator 2 (ENSG00000141258), score: -0.67 SH3GLB2SH3-domain GRB2-like endophilin B2 (ENSG00000148341), score: -0.6 SH3RF1SH3 domain containing ring finger 1 (ENSG00000154447), score: -0.57 SLC16A10solute carrier family 16, member 10 (aromatic amino acid transporter) (ENSG00000112394), score: 0.63 SLC16A2solute carrier family 16, member 2 (monocarboxylic acid transporter 8) (ENSG00000147100), score: 0.49 SLC25A17solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 (ENSG00000100372), score: 0.6 SLC25A40solute carrier family 25, member 40 (ENSG00000075303), score: 0.49 SLC25A47solute carrier family 25, member 47 (ENSG00000140107), score: 0.65 SLC2A2solute carrier family 2 (facilitated glucose transporter), member 2 (ENSG00000163581), score: 0.54 SLC2A9solute carrier family 2 (facilitated glucose transporter), member 9 (ENSG00000109667), score: 0.7 SLC30A1solute carrier family 30 (zinc transporter), member 1 (ENSG00000170385), score: 0.66 SLC30A6solute carrier family 30 (zinc transporter), member 6 (ENSG00000152683), score: 0.53 SLC30A7solute carrier family 30 (zinc transporter), member 7 (ENSG00000162695), score: 0.66 SLC31A1solute carrier family 31 (copper transporters), member 1 (ENSG00000136868), score: 0.55 SLC37A1solute carrier family 37 (glycerol-3-phosphate transporter), member 1 (ENSG00000160190), score: -0.6 SLC38A4solute carrier family 38, member 4 (ENSG00000139209), score: 0.72 SLC39A8solute carrier family 39 (zinc transporter), member 8 (ENSG00000138821), score: 0.5 SLC39A9solute carrier family 39 (zinc transporter), member 9 (ENSG00000029364), score: 0.7 SLC45A3solute carrier family 45, member 3 (ENSG00000158715), score: 0.48 SLC46A1solute carrier family 46 (folate transporter), member 1 (ENSG00000076351), score: 0.73 SLC7A2solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 (ENSG00000003989), score: 0.78 SLC7A6solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (ENSG00000103064), score: -0.8 SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 (ENSG00000082014), score: -0.59 SMYD4SET and MYND domain containing 4 (ENSG00000186532), score: -0.62 SNED1sushi, nidogen and EGF-like domains 1 (ENSG00000162804), score: -0.6 SNRNP48small nuclear ribonucleoprotein 48kDa (U11/U12) (ENSG00000168566), score: 0.49 SNX24sorting nexin 24 (ENSG00000064652), score: 0.68 SPIRE1spire homolog 1 (Drosophila) (ENSG00000134278), score: -0.66 SPP2secreted phosphoprotein 2, 24kDa (ENSG00000072080), score: 0.72 SS18synovial sarcoma translocation, chromosome 18 (ENSG00000141380), score: 0.51 SSR3signal sequence receptor, gamma (translocon-associated protein gamma) (ENSG00000114850), score: 0.6 ST6GAL1ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 (ENSG00000073849), score: 0.5 STAB2stabilin 2 (ENSG00000136011), score: 0.59 STARD5StAR-related lipid transfer (START) domain containing 5 (ENSG00000172345), score: 0.81 STK39serine threonine kinase 39 (ENSG00000198648), score: -0.6 SUCLG1succinate-CoA ligase, alpha subunit (ENSG00000163541), score: 0.47 SUPV3L1suppressor of var1, 3-like 1 (S. cerevisiae) (ENSG00000156502), score: 0.47 TATtyrosine aminotransferase (ENSG00000198650), score: 0.72 TBC1D8BTBC1 domain family, member 8B (with GRAM domain) (ENSG00000133138), score: 0.6 TDO2tryptophan 2,3-dioxygenase (ENSG00000151790), score: 0.68 TLN2talin 2 (ENSG00000171914), score: -0.67 TLR3toll-like receptor 3 (ENSG00000164342), score: 0.64 TMCO3transmembrane and coiled-coil domains 3 (ENSG00000150403), score: -0.67 TMED5transmembrane emp24 protein transport domain containing 5 (ENSG00000117500), score: 0.56 TMEM135transmembrane protein 135 (ENSG00000166575), score: 0.76 TMEM14Atransmembrane protein 14A (ENSG00000096092), score: 0.47 TMEM20transmembrane protein 20 (ENSG00000176273), score: 0.55 TMEM33transmembrane protein 33 (ENSG00000109133), score: 0.51 TMEM38Atransmembrane protein 38A (ENSG00000072954), score: -0.68 TMEM41Atransmembrane protein 41A (ENSG00000163900), score: 0.48 TMEM55Atransmembrane protein 55A (ENSG00000155099), score: -0.57 TMEM9transmembrane protein 9 (ENSG00000116857), score: -0.68 TNMDtenomodulin (ENSG00000000005), score: 0.55 TOE1target of EGR1, member 1 (nuclear) (ENSG00000132773), score: 0.5 TOM1L2target of myb1-like 2 (chicken) (ENSG00000175662), score: -0.69 TOR1Btorsin family 1, member B (torsin B) (ENSG00000136816), score: 0.49 TOR2Atorsin family 2, member A (ENSG00000160404), score: 0.48 TP53BP1tumor protein p53 binding protein 1 (ENSG00000067369), score: -0.82 TP53INP1tumor protein p53 inducible nuclear protein 1 (ENSG00000164938), score: 0.61 TRAM2translocation associated membrane protein 2 (ENSG00000065308), score: 0.63 TRPM7transient receptor potential cation channel, subfamily M, member 7 (ENSG00000092439), score: 0.51 TSR1TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) (ENSG00000167721), score: 0.48 TTC36tetratricopeptide repeat domain 36 (ENSG00000172425), score: 0.57 TTPAtocopherol (alpha) transfer protein (ENSG00000137561), score: 0.73 TWISTNBTWIST neighbor (ENSG00000105849), score: 0.75 TWSG1twisted gastrulation homolog 1 (Drosophila) (ENSG00000128791), score: -0.91 TXNDC12thioredoxin domain containing 12 (endoplasmic reticulum) (ENSG00000117862), score: 0.54 TXNDC15thioredoxin domain containing 15 (ENSG00000113621), score: 0.47 TXNRD1thioredoxin reductase 1 (ENSG00000198431), score: 0.49 UBXN4UBX domain protein 4 (ENSG00000144224), score: 0.48 UHRF1BP1LUHRF1 binding protein 1-like (ENSG00000111647), score: 0.48 UNC119unc-119 homolog (C. elegans) (ENSG00000109103), score: -0.56 UPB1ureidopropionase, beta (ENSG00000100024), score: 0.5 USO1USO1 vesicle docking protein homolog (yeast) (ENSG00000138768), score: 0.71 USP20ubiquitin specific peptidase 20 (ENSG00000136878), score: -0.63 UTP15UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) (ENSG00000164338), score: 0.56 VLDLRvery low density lipoprotein receptor (ENSG00000147852), score: -0.61 VSIG4V-set and immunoglobulin domain containing 4 (ENSG00000155659), score: 0.7 WDFY2WD repeat and FYVE domain containing 2 (ENSG00000139668), score: 0.66 WDR43WD repeat domain 43 (ENSG00000163811), score: 0.62 WDR6WD repeat domain 6 (ENSG00000178252), score: -0.59 WLSwntless homolog (Drosophila) (ENSG00000116729), score: -0.58 WNT9Awingless-type MMTV integration site family, member 9A (ENSG00000143816), score: 0.63 XCR1chemokine (C motif) receptor 1 (ENSG00000173578), score: 0.61 XKR9XK, Kell blood group complex subunit-related family, member 9 (ENSG00000221947), score: 1 XRCC6BP1XRCC6 binding protein 1 (ENSG00000166896), score: 0.48 YTHDC2YTH domain containing 2 (ENSG00000047188), score: -0.58 ZBTB2zinc finger and BTB domain containing 2 (ENSG00000181472), score: 0.61 ZC3H12Dzinc finger CCCH-type containing 12D (ENSG00000178199), score: 0.84 ZMPSTE24zinc metallopeptidase (STE24 homolog, S. cerevisiae) (ENSG00000084073), score: 0.6 ZNF326zinc finger protein 326 (ENSG00000162664), score: 0.57

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
mdo_lv_f_ca1	mdo	lv	f	_
mdo_lv_m_ca1	mdo	lv	m	_
oan_lv_f_ca1	oan	lv	f	_
oan_lv_m_ca1	oan	lv	m	_