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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

adaptive immune response

An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).

immune effector process

Any process of the immune system that occurs as part of an immune response.

activation of immune response

Any process that initiates an immune response.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

leukocyte mediated immunity

Any process involved in the carrying out of an immune response by a leukocyte.

lymphocyte mediated immunity

Any process involved in the carrying out of an immune response by a lymphocyte.

humoral immune response mediated by circulating immunoglobulin

An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies). An example of this is the adaptive immune response found in Mus musculus.

acute inflammatory response

Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.

activation of plasma proteins involved in acute inflammatory response

Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

protein maturation by peptide bond cleavage

The hydrolysis of a peptide bond or bonds within a protein as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

cellular amino acid derivative metabolic process

The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.

lipid metabolic process

The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

cellular aromatic compound metabolic process

The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.

nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

complement activation, alternative pathway

Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.

complement activation, classical pathway

Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.

humoral immune response

An immune response mediated through a body fluid.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

bile acid metabolic process

The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.

catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

aromatic amino acid family metabolic process

The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

aromatic amino acid family catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

amine catabolic process

The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to organic substance

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.

gene expression

The process by which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.

lipid catabolic process

The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

organic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.

immunoglobulin mediated immune response

An immune response mediated by immunoglobulins, whether cell-bound or in solution.

protein processing

Any protein maturation process achieved by the cleavage of peptide bonds.

aromatic compound catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

B cell mediated immunity

Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.

carboxylic acid metabolic process

The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

monocarboxylic acid metabolic process

The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

homeostatic process

Any biological process involved in the maintenance of an internal steady-state.

cholesterol homeostasis

Any process involved in the maintenance of an internal steady-state of cholesterol within an organism or cell.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

cellular amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

small molecule metabolic process

The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass.

small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.

innate immune response

Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

carboxylic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

chemical homeostasis

Any biological process involved in the maintenance of an internal steady-state of a chemical.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

cofactor metabolic process

The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.

protein maturation

Any process leading to the attainment of the full functional capacity of a protein.

lipid homeostasis

Any process involved in the maintenance of an internal steady-state of lipid within an organism or cell.

sterol homeostasis

Any process involved in the maintenance of an internal steady-state of sterol within an organism or cell.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

all

NA

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

immune effector process

Any process of the immune system that occurs as part of an immune response.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

cellular amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

organic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.

protein maturation

Any process leading to the attainment of the full functional capacity of a protein.

organic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.

aromatic compound catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

lipid catabolic process

The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

activation of immune response

Any process that initiates an immune response.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

complement activation, alternative pathway

Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.

innate immune response

Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

aromatic amino acid family metabolic process

The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

aromatic amino acid family catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

B cell mediated immunity

Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.

complement activation, classical pathway

Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.

aromatic amino acid family catabolic process

The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

carboxylic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.

activation of plasma proteins involved in acute inflammatory response

Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.

bile acid metabolic process

The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.

humoral immune response mediated by circulating immunoglobulin

An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

membrane attack complex

A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

stored secretory granule

A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.

endomembrane system

A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.

pore complex

Any small opening in a membrane that allows the passage of gases and/or liquids.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

organelle membrane

The lipid bilayer surrounding an organelle.

platelet alpha granule

A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).

platelet alpha granule lumen

The volume enclosed by the membrane of the platelet alpha granule.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

membrane-enclosed lumen

The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

vesicle lumen

The volume enclosed by the membrane or protein that forms a vesicle.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

nuclear membrane-endoplasmic reticulum network

The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

organelle lumen

The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

endoplasmic reticulum part

Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

cytoplasmic membrane-bounded vesicle lumen

The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.

subsynaptic reticulum

An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.

all

NA

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

organelle lumen

The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.

organelle membrane

The lipid bilayer surrounding an organelle.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

organelle membrane

The lipid bilayer surrounding an organelle.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

nuclear membrane-endoplasmic reticulum network

The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

nuclear membrane-endoplasmic reticulum network

The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

vesicle lumen

The volume enclosed by the membrane or protein that forms a vesicle.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

cytoplasmic membrane-bounded vesicle lumen

The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

endoplasmic reticulum part

Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

subsynaptic reticulum

An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.

membrane attack complex

A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cytoplasmic membrane-bounded vesicle lumen

The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.

endoplasmic reticulum part

Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.

endoplasmic reticulum part

Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.

pore complex

Any small opening in a membrane that allows the passage of gases and/or liquids.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

membrane attack complex

A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

platelet alpha granule lumen

The volume enclosed by the membrane of the platelet alpha granule.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

metal ion binding

Interacting selectively and non-covalently with any metal ion.

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

amino acid binding

Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.

lyase activity

Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.

vitamin binding

Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.

pyridoxal phosphate binding

Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

carboxylic acid binding

Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

ion binding

Interacting selectively and non-covalently with ions, charged atoms or groups of atoms.

cation binding

Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge.

amine binding

Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group.

transition metal ion binding

Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

cofactor binding

Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.

vitamin B6 binding

Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.

all

NA

amino acid binding

Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.

pyridoxal phosphate binding

Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0006082	4.774e-08	17.81	48 ACOT12, ACSL5, ADIPOQ, AFMID, AGXT, AKR1D1, ALDH9A1, AMDHD1, ASPG, ATP8B1, AVPR1A, BCKDHB, CCBL1, CDO1, CYP39A1, DPYS, FGF19, FH, GCH1, GCLM, GLDC, GNMT, HAL, HAO1, HAO2, HGD, HTT, KMO, LIPC, MAT1A, MSRA, NPC1, NR5A2, OTC, P4HA1, PAH, PARS2, PCK2, PEX13, RBP4, SDSL, SGPL1, SLC7A2, SLC7A6, TARSL2, TAT, TDO2, TMEM195	228	organic acid metabolic process
GO:0019752	4.774e-08	17.81	48 ACOT12, ACSL5, ADIPOQ, AFMID, AGXT, AKR1D1, ALDH9A1, AMDHD1, ASPG, ATP8B1, AVPR1A, BCKDHB, CCBL1, CDO1, CYP39A1, DPYS, FGF19, FH, GCH1, GCLM, GLDC, GNMT, HAL, HAO1, HAO2, HGD, HTT, KMO, LIPC, MAT1A, MSRA, NPC1, NR5A2, OTC, P4HA1, PAH, PARS2, PCK2, PEX13, RBP4, SDSL, SGPL1, SLC7A2, SLC7A6, TARSL2, TAT, TDO2, TMEM195	228	carboxylic acid metabolic process
GO:0043436	4.774e-08	17.81	48 ACOT12, ACSL5, ADIPOQ, AFMID, AGXT, AKR1D1, ALDH9A1, AMDHD1, ASPG, ATP8B1, AVPR1A, BCKDHB, CCBL1, CDO1, CYP39A1, DPYS, FGF19, FH, GCH1, GCLM, GLDC, GNMT, HAL, HAO1, HAO2, HGD, HTT, KMO, LIPC, MAT1A, MSRA, NPC1, NR5A2, OTC, P4HA1, PAH, PARS2, PCK2, PEX13, RBP4, SDSL, SGPL1, SLC7A2, SLC7A6, TARSL2, TAT, TDO2, TMEM195	228	oxoacid metabolic process
GO:0042180	9.513e-08	18.2	48 ACOT12, ACSL5, ADIPOQ, AFMID, AGXT, AKR1D1, ALDH9A1, AMDHD1, ASPG, ATP8B1, AVPR1A, BCKDHB, CCBL1, CDO1, CYP39A1, DPYS, FGF19, FH, GCH1, GCLM, GLDC, GNMT, HAL, HAO1, HAO2, HGD, HTT, KMO, LIPC, MAT1A, MSRA, NPC1, NR5A2, OTC, P4HA1, PAH, PARS2, PCK2, PEX13, RBP4, SDSL, SGPL1, SLC7A2, SLC7A6, TARSL2, TAT, TDO2, TMEM195	233	cellular ketone metabolic process
GO:0006519	1.182e-07	10.31	34 AFMID, AGXT, ALDH9A1, AMDHD1, ASPG, BCKDHB, CCBL1, CDO1, DPYS, ETNK2, GCH1, GCLM, GLDC, GLO1, GNMT, HAGH, HAL, HGD, HTT, KMO, LIPC, MAT1A, MSRA, OTC, P4HA1, PAH, PARS2, PEMT, SDSL, SLC7A2, SLC7A6, TARSL2, TAT, TDO2	132	cellular amino acid and derivative metabolic process
GO:0044106	1.734e-07	8.904	31 AFMID, AGXT, ALDH9A1, AMDHD1, ASPG, BCKDHB, CCBL1, CDO1, DPYS, ETNK2, GCH1, GCLM, GLDC, GNMT, HAL, HGD, HTT, KMO, LIPC, MAT1A, MSRA, OTC, PAH, PARS2, PEMT, SDSL, SLC7A2, SLC7A6, TARSL2, TAT, TDO2	114	cellular amine metabolic process
GO:0006520	9.465e-07	7.03	26 AFMID, AGXT, AMDHD1, ASPG, BCKDHB, CCBL1, CDO1, DPYS, GCLM, GLDC, GNMT, HAL, HGD, HTT, KMO, MAT1A, MSRA, OTC, PAH, PARS2, SDSL, SLC7A2, SLC7A6, TARSL2, TAT, TDO2	90	cellular amino acid metabolic process
GO:0009308	1.014e-06	11.79	35 ACER3, AFMID, AGXT, ALDH9A1, AMDHD1, ASPG, BCKDHB, CCBL1, CDO1, CTBS, DPYS, ETNK2, GCH1, GCLM, GLDC, GNMT, HAL, HGD, HTT, KMO, LIPC, LYVE1, MAT1A, MSRA, OTC, P4HA1, PAH, PARS2, PEMT, SDSL, SLC7A2, SLC7A6, TARSL2, TAT, TDO2	151	amine metabolic process
GO:0016054	2.694e-06	3.749	18 ACSL5, ADIPOQ, AFMID, AKR1D1, AMDHD1, BCKDHB, CDO1, CYP39A1, GLDC, HAL, HAO1, HAO2, HGD, KMO, PAH, PEX13, TAT, TDO2	48	organic acid catabolic process
GO:0046395	2.694e-06	3.749	18 ACSL5, ADIPOQ, AFMID, AKR1D1, AMDHD1, BCKDHB, CDO1, CYP39A1, GLDC, HAL, HAO1, HAO2, HGD, KMO, PAH, PEX13, TAT, TDO2	48	carboxylic acid catabolic process
GO:0006956	3.352e-05	0.6249	7 C5, C8A, C8B, C8G, MASP1, MASP2, VSIG4	8	complement activation
GO:0019439	3.352e-05	0.6249	7 AFMID, EPHX1, HGD, KMO, PAH, TAT, TDO2	8	aromatic compound catabolic process
GO:0009074	5.285e-05	0.4686	6 AFMID, HGD, KMO, PAH, TAT, TDO2	6	aromatic amino acid family catabolic process
GO:0002541	1.103e-04	0.703	7 C5, C8A, C8B, C8G, MASP1, MASP2, VSIG4	9	activation of plasma proteins involved in acute inflammatory response
GO:0009611	1.147e-04	16.48	38 ACE2, ADIPOQ, ATRN, BDKRB1, BMP2, C5, C8A, C8B, C8G, CDO1, CPB2, F10, F2, F9, FGB, FGG, FN1, HRG, IGFBP1, JAK2, LYVE1, MASP1, MASP2, NT5E, P2RY2, PLAT, PROZ, SCARB1, SDC2, SERPINA10, SERPINC1, SERPINF2, STAB1, TLR3, TM4SF4, TPST1, VSIG4, VTN	211	response to wounding
GO:0009056	1.790e-04	32.49	60 ACE2, ACSL5, ADIPOQ, ADPGK, AFMID, AKR1D1, AMBP, AMDHD1, ASAP1, ASPG, AXIN1, BCKDHB, BTRC, CDO1, CLPX, CTBS, CYP39A1, DERL1, DHCR24, DHTKD1, DNAJC3, DPYS, EPHX1, ERLEC1, FBXO4, FH, GCH1, GLDC, H6PD, HAL, HAO1, HAO2, HGD, HM13, KMO, LIPC, LYVE1, NAGA, NCSTN, NPC1, NT5E, PAFAH1B2, PAH, PCSK9, PDE3B, PEX13, PLA2G12B, PSMA3, PYGL, RALGAPA1, RNF103, SCARB1, SGPL1, TAT, TDO2, USP20, USP34, USP53, USP54, ZMPSTE24	416	catabolic process
GO:0006575	1.922e-04	4.53	17 AFMID, ALDH9A1, CCBL1, CDO1, ETNK2, GCH1, GCLM, GLO1, GNMT, HAGH, HTT, KMO, LIPC, P4HA1, PAH, PEMT, TDO2	58	cellular amino acid derivative metabolic process
GO:0006957	4.384e-04	0.3905	5 C5, C8A, C8B, C8G, VSIG4	5	complement activation, alternative pathway
GO:0009063	5.361e-04	2.187	11 AFMID, AMDHD1, BCKDHB, CDO1, GLDC, HAL, HGD, KMO, PAH, TAT, TDO2	28	cellular amino acid catabolic process
GO:0009310	7.460e-04	2.265	11 AFMID, AMDHD1, BCKDHB, CDO1, GLDC, HAL, HGD, KMO, PAH, TAT, TDO2	29	amine catabolic process
GO:0006725	7.889e-04	3.593	14 AFMID, DPYS, EPHX1, GCH1, GNMT, GPHN, HAO2, HGD, KMO, MOCOS, PAH, PEMT, TAT, TDO2	46	cellular aromatic compound metabolic process
GO:0006959	9.896e-04	1.562	9 BST1, C5, C8A, C8B, C8G, HPX, MASP1, MASP2, VSIG4	20	humoral immune response
GO:0006629	1.144e-03	24.14	46 ABCA1, ACER3, ACOT12, ACSL5, ADIPOQ, AKR1D1, ASPG, ATP8B1, AVPR1A, CEPT1, COL4A3BP, CRLS1, CYP2R1, CYP39A1, DHCR24, ENPP7, ESR1, ETNK2, FGF19, GPLD1, HAO1, HAO2, LIPC, LPCAT3, MTTP, NAGA, NPC1, NR5A2, PAFAH1B2, PCSK9, PDE3B, PEMT, PEX13, PIK3C3, PIP5K1C, PLA2G12B, RBP4, SAMD8, SCARB1, SDR42E1, SERINC5, SGPL1, SLC35C1, STARD5, TMEM195, TTPA	309	lipid metabolic process
GO:0051186	1.378e-03	5.311	17 ACOT12, ALAD, ALAS1, AMBP, CIAO1, FH, GCH1, GCLM, GLO1, GPHN, H6PD, HAGH, HPX, KMO, MOCOS, NAPRT1, TDO2	68	cofactor metabolic process
GO:0044281	1.382e-03	47.02	75 ABCA1, ACER3, ACOT12, ACSL5, ADIPOQ, ADPGK, AFMID, AGXT, AKAP12, AKR1D1, ALDH9A1, ALKBH1, AMDHD1, ASAP1, ASPG, ATP8B1, AVPR1A, BCKDHB, CA6, CCBL1, CDO1, CTCF, CYP2R1, CYP39A1, DHCR24, DHTKD1, DPYS, ETNK2, FGF19, FH, GCH1, GCLM, GLDC, GLO1, GNMT, H6PD, HAGH, HAL, HAO1, HAO2, HGD, HTT, KMO, LIPC, MAT1A, MSRA, MTAP, NAPRT1, NPC1, NR5A2, NT5E, ONECUT1, OTC, P4HA1, PAH, PARS2, PCK2, PCSK9, PDE3B, PEMT, PEX13, PGM3, PYGL, RALGAPA1, RBP4, SCARB1, SDSL, SGPL1, SLC7A2, SLC7A6, TARSL2, TAT, TDO2, TMEM195, TTPA	602	small molecule metabolic process
GO:0002455	1.725e-03	0.703	6 C5, C8A, C8B, C8G, HPX, MASP2	9	humoral immune response mediated by circulating immunoglobulin
GO:0009072	1.725e-03	0.703	6 AFMID, HGD, KMO, PAH, TAT, TDO2	9	aromatic amino acid family metabolic process
GO:0006958	1.812e-03	0.4686	5 C5, C8A, C8B, C8G, MASP2	6	complement activation, classical pathway
GO:0016042	3.586e-03	4.686	15 ACSL5, ADIPOQ, AKR1D1, ASPG, CYP39A1, HAO1, HAO2, LIPC, NAGA, PAFAH1B2, PDE3B, PEX13, PLA2G12B, SCARB1, SGPL1	60	lipid catabolic process
GO:0044282	3.675e-03	11.95	27 ACSL5, ADIPOQ, ADPGK, AFMID, AKR1D1, AMDHD1, ASAP1, BCKDHB, CDO1, CYP39A1, DHTKD1, DPYS, GCH1, GLDC, H6PD, HAL, HAO1, HAO2, HGD, KMO, NT5E, PAH, PDE3B, PEX13, RALGAPA1, TAT, TDO2	153	small molecule catabolic process
GO:0006954	4.586e-03	8.904	22 ACE2, ADIPOQ, ATRN, BDKRB1, BMP2, C5, C8A, C8B, C8G, CDO1, F2, FN1, JAK2, MASP1, MASP2, NT5E, SERPINC1, SERPINF2, STAB1, TLR3, TPST1, VSIG4	114	inflammatory response
GO:0042221	4.613e-03	40.77	65 ACP2, ACSL5, ACVR1C, ADIPOQ, AGXT, ALG2, AQP8, ATRN, AVPR1A, BCKDHB, BDKRB1, BLMH, BMP2, BTRC, C5, CD86, CDH1, CDO1, CPB2, DDOST, DERL1, DHCR24, DNAJC3, EDEM3, EGFR, EPHX1, ERP44, ESR1, FAF2, FGB, FGG, GCH1, GCLM, HAO1, HPX, HTT, IGF1R, IGFBP1, IHH, JAK2, LECT2, LYN, MSRA, NAPRT1, NPC1, P2RY2, PCK2, PCSK9, PDE3B, PEMT, PHIP, PLAT, RBP4, ROBO1, SCARB1, SDC2, SERPINC1, SERPINF2, SLC25A12, SSH1, TAT, TLR3, TTPA, UBXN4, VASH1	522	response to chemical stimulus
GO:0010033	5.861e-03	26.09	46 ACP2, ACSL5, ACVR1C, ADIPOQ, AGXT, AQP8, AVPR1A, BCKDHB, BDKRB1, BMP2, BTRC, CD86, CDH1, CDO1, DDOST, DERL1, DNAJC3, EDEM3, EGFR, EPHX1, ERP44, ESR1, FAF2, GCH1, HPX, IGF1R, IGFBP1, IHH, JAK2, LYN, P2RY2, PCK2, PCSK9, PDE3B, PEMT, PHIP, PLAT, RBP4, SCARB1, SDC2, SERPINF2, SSH1, TAT, TLR3, UBXN4, VASH1	334	response to organic substance
GO:0008206	6.020e-03	0.8592	6 AKR1D1, ATP8B1, CYP39A1, FGF19, NPC1, NR5A2	11	bile acid metabolic process
GO:0042632	6.020e-03	0.8592	6 ABCA1, LIPC, NPC1, NR5A2, PCSK9, SCARB1	11	cholesterol homeostasis
GO:0055092	6.020e-03	0.8592	6 ABCA1, LIPC, NPC1, NR5A2, PCSK9, SCARB1	11	sterol homeostasis
GO:0016485	6.263e-03	2.89	11 C5, C8A, C8B, C8G, DHCR24, IHH, MASP1, MASP2, NCSTN, PCSK9, VSIG4	37	protein processing
GO:0051604	6.263e-03	2.89	11 C5, C8A, C8B, C8G, DHCR24, IHH, MASP1, MASP2, NCSTN, PCSK9, VSIG4	37	protein maturation
GO:0048583	6.800e-03	14.53	30 ACE2, ADIPOQ, AMBP, AXIN1, C5, C8A, C8B, C8G, CD86, CPB2, F2, FGF19, HPX, HRG, JAK2, LYN, MASP1, MASP2, NPC1, NT5E, POLR3F, RBP4, ROBO1, SERPINC1, SERPINF2, TLR3, UIMC1, VSIG4, VTN, ZAP70	186	regulation of response to stimulus
GO:0044248	7.469e-03	27.18	47 ACSL5, ADIPOQ, AFMID, AKR1D1, AMBP, AMDHD1, ASAP1, BCKDHB, BTRC, CDO1, CLPX, CYP39A1, DERL1, DNAJC3, DPYS, EPHX1, ERLEC1, FBXO4, FH, GCH1, GLDC, HAL, HAO1, HAO2, HGD, HM13, KMO, LIPC, NAGA, NCSTN, NPC1, NT5E, PAH, PCSK9, PDE3B, PEX13, PSMA3, RALGAPA1, RNF103, SGPL1, TAT, TDO2, USP20, USP34, USP53, USP54, ZMPSTE24	348	cellular catabolic process
GO:0032787	8.410e-03	9.998	23 ACOT12, ACSL5, ADIPOQ, AGXT, AKR1D1, ALDH9A1, ATP8B1, AVPR1A, CYP39A1, FGF19, GCH1, GNMT, HAO1, HAO2, HTT, LIPC, NPC1, NR5A2, P4HA1, PCK2, PEX13, RBP4, TMEM195	128	monocarboxylic acid metabolic process
GO:0042060	8.604e-03	6.873	18 CPB2, F10, F2, F9, FGB, FGG, HRG, IGFBP1, P2RY2, PLAT, PROZ, SCARB1, SDC2, SERPINA10, SERPINC1, SERPINF2, TM4SF4, VTN	88	wound healing
GO:0051605	9.528e-03	2.109	9 C5, C8A, C8B, C8G, DHCR24, MASP1, MASP2, PCSK9, VSIG4	27	protein maturation by peptide bond cleavage
GO:0002253	9.849e-03	2.578	10 C5, C8A, C8B, C8G, CD86, MASP1, MASP2, TLR3, VSIG4, ZAP70	33	activation of immune response
GO:0002526	9.849e-03	2.578	10 C5, C8A, C8B, C8G, F2, FN1, MASP1, MASP2, SERPINF2, VSIG4	33	acute inflammatory response
GO:0006950	1.098e-02	48.11	72 ACE2, ADIPOQ, ALB, ALKBH1, AMBP, ATRN, AVPR1A, AXIN1, BDKRB1, BMP2, C5, C8A, C8B, C8G, CD86, CDO1, COL4A3BP, CPB2, DERL1, DHCR24, DNAJC3, EDEM3, EGFR, ERP44, F10, F2, F9, FAF2, FGB, FGF19, FGG, FN1, GCH1, GCLM, GPR132, HAO1, HPX, HRG, IGFBP1, JAK2, KMO, LEAP2, LYN, LYVE1, MASP1, MASP2, MSRA, NAPRT1, NPC1, NT5E, P2RY2, PCSK9, PLAT, POLR3F, PROZ, SCARB1, SDC2, SERPINA10, SERPINC1, SERPINF2, STAB1, STAB2, TAT, TLR3, TM4SF4, TP53BP1, TPST1, UBXN4, UIMC1, VSIG4, VTN, XRCC6BP1	616	response to stress
GO:0055088	1.140e-02	1.328	7 ABCA1, COL4A3BP, LIPC, NPC1, NR5A2, PCSK9, SCARB1	17	lipid homeostasis
GO:0006952	1.162e-02	13.67	28 ACE2, ADIPOQ, ATRN, BDKRB1, BMP2, C5, C8A, C8B, C8G, CD86, CDO1, F2, FN1, GCH1, HPX, JAK2, LEAP2, MASP1, MASP2, NT5E, POLR3F, SERPINC1, SERPINF2, STAB1, STAB2, TLR3, TPST1, VSIG4	175	defense response
GO:0051917	1.188e-02	0.3905	4 CPB2, F2, HRG, SERPINF2	5	regulation of fibrinolysis
GO:0051918	1.188e-02	0.3905	4 CPB2, F2, HRG, SERPINF2	5	negative regulation of fibrinolysis
GO:0080134	1.194e-02	8.982	21 ACE2, ADIPOQ, AMBP, AXIN1, CD86, CPB2, F2, FGF19, HPX, HRG, JAK2, LYN, MASP1, NPC1, NT5E, POLR3F, SERPINC1, SERPINF2, TLR3, UIMC1, VTN	115	regulation of response to stress
GO:0008202	1.462e-02	6.014	16 ABCA1, AKR1D1, ATP8B1, CYP2R1, CYP39A1, DHCR24, ESR1, FGF19, LIPC, NPC1, NR5A2, PCSK9, SCARB1, SDR42E1, SGPL1, STARD5	77	steroid metabolic process
GO:0046364	1.506e-02	1.015	6 ADIPOQ, GNMT, PCK2, PGM3, PYGL, RBP4	13	monosaccharide biosynthetic process
GO:0007596	1.726e-02	3.827	12 CPB2, F10, F2, F9, FGB, FGG, HRG, PLAT, PROZ, SERPINC1, SERPINF2, VTN	49	blood coagulation
GO:0065008	1.905e-02	49.21	72 A1CF, ABCA1, ACE2, ACVR1C, ACVR2A, ADIPOQ, AKR1D1, ALB, ALDH9A1, AVPR1A, BBS2, BDKRB1, BMP2, CDKN2AIP, CDO1, CISH, CLDN1, COL4A3BP, COPA, CPB2, DERL1, ERP44, ESR1, F10, F2, F9, FBXO4, FGB, FGG, FH, FN1, FST, GAS2, GCH1, GCHFR, GCLM, GDF2, HPX, HRG, HTT, IBTK, IGFBP1, JAK2, LIPC, LYN, MAP2K5, MAPT, NOP58, NPC1, NR5A2, OTC, P2RY2, PAH, PCSK9, PDE3B, PLAT, PRDX4, PROZ, PYGL, RBP4, RHOU, SCARB1, SERPINC1, SERPINF2, SGPL1, SLC16A2, SLC30A1, SLC30A7, TLN2, TLR3, TXNDC15, VTN	630	regulation of biological quality
GO:0007599	2.017e-02	3.905	12 CPB2, F10, F2, F9, FGB, FGG, HRG, PLAT, PROZ, SERPINC1, SERPINF2, VTN	50	hemostasis
GO:0032101	2.019e-02	5.624	15 ACE2, ADIPOQ, C5, CPB2, F2, HRG, JAK2, MASP1, NPC1, NT5E, ROBO1, SERPINC1, SERPINF2, TLR3, VTN	72	regulation of response to external stimulus
GO:0006732	2.328e-02	3.983	12 ACOT12, FH, GCH1, GCLM, GLO1, GPHN, H6PD, HAGH, KMO, MOCOS, NAPRT1, TDO2	51	coenzyme metabolic process
GO:0050778	2.328e-02	3.983	12 C5, C8A, C8B, C8G, CD86, HPX, MASP1, MASP2, POLR3F, TLR3, VSIG4, ZAP70	51	positive regulation of immune response
GO:0050817	2.328e-02	3.983	12 CPB2, F10, F2, F9, FGB, FGG, HRG, PLAT, PROZ, SERPINC1, SERPINF2, VTN	51	coagulation
GO:0001561	2.564e-02	0.2343	3 HAO1, HAO2, PEX13	3	fatty acid alpha-oxidation
GO:0006558	2.564e-02	0.2343	3 HGD, PAH, TAT	3	L-phenylalanine metabolic process
GO:0006559	2.564e-02	0.2343	3 HGD, PAH, TAT	3	L-phenylalanine catabolic process
GO:0006569	2.564e-02	0.2343	3 AFMID, KMO, TDO2	3	tryptophan catabolic process
GO:0042436	2.564e-02	0.2343	3 AFMID, KMO, TDO2	3	indole derivative catabolic process
GO:0046218	2.564e-02	0.2343	3 AFMID, KMO, TDO2	3	indolalkylamine catabolic process
GO:0044283	2.574e-02	14.53	28 ABCA1, ACER3, ADIPOQ, AGXT, AKAP12, AKR1D1, ATP8B1, AVPR1A, CDO1, CYP39A1, ETNK2, FGF19, GCH1, GCLM, GNMT, HAGH, HTT, KMO, LIPC, NAPRT1, NT5E, OTC, PAH, PCK2, PGM3, PYGL, RBP4, TMEM195	186	small molecule biosynthetic process
GO:0019835	2.604e-02	0.4686	4 C5, C8A, C8B, C8G	6	cytolysis
GO:0030194	2.604e-02	0.4686	4 CPB2, F2, HRG, SERPINF2	6	positive regulation of blood coagulation
GO:0042730	2.604e-02	0.4686	4 CPB2, F2, HRG, SERPINF2	6	fibrinolysis
GO:0030195	2.712e-02	0.7811	5 CPB2, F2, HRG, SERPINF2, VTN	10	negative regulation of blood coagulation
GO:0006576	2.829e-02	2.499	9 AFMID, ALDH9A1, ETNK2, GCH1, KMO, LIPC, PAH, PEMT, TDO2	32	cellular biogenic amine metabolic process
GO:0048584	3.045e-02	7.811	18 AXIN1, C5, C8A, C8B, C8G, CD86, FGF19, HPX, JAK2, LYN, MASP1, MASP2, POLR3F, TLR3, UIMC1, VSIG4, VTN, ZAP70	100	positive regulation of response to stimulus
GO:0045087	3.055e-02	4.14	12 C5, C8A, C8B, C8G, CD86, GCH1, HPX, MASP1, MASP2, POLR3F, TLR3, VSIG4	53	innate immune response
GO:0010876	3.304e-02	4.765	13 ABCA1, ABCA5, ACSL5, ACVR1C, ADIPOQ, ATP8B1, COL4A3BP, LIPC, NPC1, P2RY2, RBP4, SCARB1, STARD5	61	lipid localization
GO:0051188	3.596e-02	3.124	10 ALAD, ALAS1, CIAO1, GCH1, GCLM, GPHN, HAGH, KMO, MOCOS, NAPRT1	40	cofactor biosynthetic process
GO:0050776	3.852e-02	5.468	14 AMBP, C5, C8A, C8B, C8G, CD86, HPX, MASP1, MASP2, POLR3F, RBP4, TLR3, VSIG4, ZAP70	70	regulation of immune response
GO:0055114	4.000e-02	15.07	28 AKR1D1, ALDH9A1, ALKBH1, BCKDHB, C17orf101, CDO1, CYP2R1, CYP39A1, DHCR24, DHTKD1, GCLM, GLDC, H6PD, HAO1, HAO2, HGD, HSDL1, IYD, KMO, MSRA, P4HA1, PAH, PRDX4, SDR42E1, SLC25A12, TDO2, TMEM195, VAT1	193	oxidation reduction
GO:0033344	4.034e-02	0.8592	5 ABCA1, ABCA5, ADIPOQ, NPC1, SCARB1	11	cholesterol efflux
GO:0050819	4.034e-02	0.8592	5 CPB2, F2, HRG, SERPINF2, VTN	11	negative regulation of coagulation
GO:0006644	4.291e-02	5.546	14 ACSL5, CEPT1, CRLS1, ENPP7, ETNK2, GPLD1, LIPC, LPCAT3, PCSK9, PEMT, PIK3C3, PIP5K1C, SAMD8, SERINC5	71	phospholipid metabolic process
GO:0046165	4.473e-02	1.718	7 ACER3, ADIPOQ, GNMT, PCK2, PGM3, PYGL, RBP4	22	alcohol biosynthetic process
GO:0006869	4.486e-02	4.374	12 ABCA1, ABCA5, ACSL5, ADIPOQ, ATP8B1, COL4A3BP, LIPC, NPC1, P2RY2, RBP4, SCARB1, STARD5	56	lipid transport
GO:0009069	4.603e-02	0.5468	4 AGXT, CDO1, GCLM, GLDC	7	serine family amino acid metabolic process
GO:0034381	4.603e-02	0.5468	4 ADIPOQ, LIPC, PCSK9, SCARB1	7	lipoprotein particle clearance
GO:0043691	4.603e-02	0.5468	4 ABCA1, ABCA5, LIPC, SCARB1	7	reverse cholesterol transport
GO:0050999	4.603e-02	0.5468	4 ACVR2A, EGFR, GCH1, SCARB1	7	regulation of nitric-oxide synthase activity

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005783	7.594e-05	27.52	53 A1CF, ACER3, ACSL5, ADIPOQ, ALG8, BDKRB1, CEPT1, CKAP4, COL4A3BP, COPA, CYP2R1, CYP39A1, DDOST, DERL1, DHCR24, DNAJC1, DNAJC3, EDEM3, EPHX1, ERGIC1, ERLEC1, ERP44, FAF2, H6PD, HM13, LPCAT3, MFSD2A, MTTP, NCSTN, NPC1, P4HA1, PCSK9, PDE3B, PEMT, PLA2G12B, PPIB, RNF103, SAR1B, SEC23A, SEC24D, SEC61A1, SERINC5, SGPL1, SLC26A11, SSR3, TLR3, TMEM195, UBXN4, VASH1, YIPF5, ZFYVE1, ZMPSTE24, ZW10	356	endoplasmic reticulum
GO:0044432	1.487e-04	17.55	38 ACER3, ACSL5, ALG8, CEPT1, COL4A3BP, CYP2R1, CYP39A1, DDOST, DERL1, DHCR24, DNAJC1, DNAJC3, EDEM3, EPHX1, ERGIC1, ERLEC1, ERP44, H6PD, HM13, LPCAT3, MFSD2A, P4HA1, PEMT, PPIB, RNF103, SAR1B, SEC23A, SEC24D, SEC61A1, SERINC5, SGPL1, SLC26A11, SSR3, TLR3, UBXN4, YIPF5, ZMPSTE24, ZW10	227	endoplasmic reticulum part
GO:0071212	1.991e-04	18.48	39 ACER3, ACSL5, ALG8, CEPT1, COL4A3BP, CYP2R1, CYP39A1, DDOST, DERL1, DHCR24, DNAJC1, DNAJC3, EDEM3, EPHX1, ERGIC1, ERLEC1, ERP44, H6PD, HM13, LPCAT3, MFSD2A, P4HA1, PCSK9, PEMT, PPIB, RNF103, SAR1B, SEC23A, SEC24D, SEC61A1, SERINC5, SGPL1, SLC26A11, SSR3, TLR3, UBXN4, YIPF5, ZMPSTE24, ZW10	239	subsynaptic reticulum
GO:0005615	3.029e-04	17.47	37 ACE2, ADIPOQ, ALB, ATRN, BMP2, C5, C8A, C8B, COPA, CPB2, EGFR, F2, FGB, FGG, FN1, GAS6, GDF2, HGF, HPX, IGFBP1, IHH, IL5RA, LECT2, LIPC, MASP1, MMP13, PCSK9, PLAT, PRDX4, PTPRG, RBP4, SDF2, SERPINC1, SERPINF2, TWSG1, VASH1, VTN	226	extracellular space
GO:0005789	5.871e-04	15.31	33 ACER3, ACSL5, ALG8, CEPT1, COL4A3BP, CYP2R1, CYP39A1, DDOST, DERL1, DHCR24, DNAJC1, DNAJC3, EPHX1, ERGIC1, ERP44, HM13, LPCAT3, MFSD2A, PEMT, RNF103, SAR1B, SEC23A, SEC24D, SEC61A1, SERINC5, SGPL1, SLC26A11, SSR3, TLR3, UBXN4, YIPF5, ZMPSTE24, ZW10	198	endoplasmic reticulum membrane
GO:0042175	1.006e-03	15.77	33 ACER3, ACSL5, ALG8, CEPT1, COL4A3BP, CYP2R1, CYP39A1, DDOST, DERL1, DHCR24, DNAJC1, DNAJC3, EPHX1, ERGIC1, ERP44, HM13, LPCAT3, MFSD2A, PEMT, RNF103, SAR1B, SEC23A, SEC24D, SEC61A1, SERINC5, SGPL1, SLC26A11, SSR3, TLR3, UBXN4, YIPF5, ZMPSTE24, ZW10	204	nuclear membrane-endoplasmic reticulum network
GO:0005579	1.180e-03	0.3093	4 C5, C8A, C8B, C8G	4	membrane attack complex
GO:0031093	1.810e-03	1.16	7 ALB, FGB, FGG, FN1, HGF, HRG, SERPINF2	15	platelet alpha granule lumen
GO:0005576	2.360e-03	41.21	65 ACE2, ADIPOQ, ADPGK, ALB, AMBP, ATRN, BMP2, C5, C8A, C8B, C8G, CA6, COPA, CPB2, CREG1, EGFR, F10, F2, F9, FAM20A, FAM3C, FETUB, FGB, FGF19, FGG, FN1, FST, GAS6, GDF2, GPLD1, HGF, HHIPL1, HPX, HRG, IGFBP1, IHH, IL5RA, ISM1, LAMB3, LEAP2, LECT2, LIPC, MASP1, MASP2, MATN1, MMP13, PCSK9, PLA2G12B, PLAT, PM20D1, PRDX4, PROZ, PRRG1, PTPRG, RBP4, SCUBE3, SDF2, SERPINA10, SERPINC1, SERPINF2, SPP2, TSKU, TWSG1, VASH1, VTN	533	extracellular region
GO:0031983	2.734e-03	1.237	7 ALB, FGB, FGG, FN1, HGF, HRG, SERPINF2	16	vesicle lumen
GO:0060205	2.734e-03	1.237	7 ALB, FGB, FGG, FN1, HGF, HRG, SERPINF2	16	cytoplasmic membrane-bounded vesicle lumen
GO:0044444	4.159e-03	142.6	176 A1CF, ABCA1, ABCA5, ACER3, ACOT12, ACP2, ACSL5, ACSS3, ADIPOQ, AFMID, AGXT, AK2, AKAP12, AKR1D1, ALAD, ALAS1, ALB, ALDH9A1, ALG2, ALG8, ALKBH1, AMDHD1, AP3M2, ARCN1, ARHGEF3, AVPR1A, AXIN1, B4GALT5, BBS2, BCKDHB, BDKRB1, BTRC, CBY1, CCBL1, CDH1, CDO1, CEPT1, CHMP6, CKAP4, CKAP5, CLIP1, CLPX, COL4A3BP, COPA, COPB1, CRLS1, CTBS, CYP2R1, CYP39A1, DDOST, DENND5A, DERL1, DHCR24, DHDPSL, DHTKD1, DNAJC1, DNAJC3, DPYS, EDEM3, EGFR, ENPP7, EPB41L2, EPHX1, ERGIC1, ERLEC1, ERP44, EXOC8, FAF2, FAM3C, FGB, FGG, FH, FN1, FZD5, GALNT7, GCH1, GCHFR, GCLM, GLDC, GNMT, GOLGA1, GOLIM4, H6PD, HAGH, HAL, HAO1, HAO2, HEBP1, HGF, HM13, HRG, HSDL1, HTT, JAK2, KMO, LACTB, LPCAT3, LYN, MAPT, MFSD2A, MRPS18A, MRPS30, MSRA, MTMR2, MTTP, NAGA, NAPRT1, NCSTN, NPC1, NUDT12, NUDT19, OTC, P2RY2, P4HA1, PARS2, PCK2, PCSK9, PDE1A, PDE3B, PEMT, PEX11A, PEX13, PIK3C3, PLA2G12B, PLAT, PPIB, PRDX4, RAB20, RAB33B, RALGAPA1, RANBP10, RASA2, RHOU, RNF103, SAR1B, SDSL, SEC23A, SEC24D, SEC61A1, SERINC5, SERPINF2, SGPL1, SLC17A5, SLC25A12, SLC25A19, SLC25A47, SLC26A11, SLC2A2, SLC30A7, SLC35C1, SPIRE1, SSR3, STARD5, STK24, TACC1, TAT, TDO2, TLR3, TM9SF2, TMEM195, TMEM33, TMEM55A, TOP2B, TPST1, TTPA, UBXN4, UNC50, USO1, USP20, VASH1, WDR44, YIPF5, ZAP70, ZFYVE1, ZMPSTE24, ZW10	1844	cytoplasmic part
GO:0031091	7.834e-03	1.469	7 ALB, FGB, FGG, FN1, HGF, HRG, SERPINF2	19	platelet alpha granule
GO:0000267	1.104e-02	29.15	47 ABCA1, ABCB11, ABCC2, ACP2, ALG2, AMBP, AQP8, ATP8B1, BDKRB1, BLMH, CKAP4, COPA, CYP2R1, CYP39A1, DDOST, DNAJC1, DPYS, EPHX1, F10, F2, FGB, GCHFR, GCLM, GLO1, H6PD, HAL, HTT, IGF1R, JAK2, LYVE1, NCSTN, NT5E, PCK2, PDE3B, PEMT, PEX13, PYGL, SCARB1, SLC16A2, SLC17A5, SLC2A2, SLC7A2, SSR3, TDO2, TPST1, USO1, ZMPSTE24	377	cell fraction
GO:0005792	1.136e-02	5.257	14 AMBP, AQP8, COPA, CYP2R1, CYP39A1, DDOST, DNAJC1, EPHX1, F10, H6PD, IGF1R, PDE3B, SSR3, USO1	68	microsome
GO:0042598	1.636e-02	5.489	14 AMBP, AQP8, COPA, CYP2R1, CYP39A1, DDOST, DNAJC1, EPHX1, F10, H6PD, IGF1R, PDE3B, SSR3, USO1	71	vesicular fraction
GO:0044421	2.290e-02	24.74	40 ACE2, ADIPOQ, ALB, ATRN, BMP2, C5, C8A, C8B, COPA, CPB2, EGFR, F2, FGB, FGG, FN1, GAS6, GDF2, GPLD1, HGF, HPX, IGFBP1, IHH, IL5RA, LAMB3, LECT2, LIPC, MASP1, MATN1, MMP13, PCSK9, PLAT, PRDX4, PTPRG, RBP4, SDF2, SERPINC1, SERPINF2, TWSG1, VASH1, VTN	320	extracellular region part
GO:0030120	2.784e-02	1.392	6 ARCN1, COPA, COPB1, EGFR, SEC23A, SEC24D	18	vesicle coat
GO:0005624	2.965e-02	21.18	35 ABCA1, ABCB11, ABCC2, ACP2, ALG2, AMBP, AQP8, ATP8B1, BDKRB1, CKAP4, COPA, CYP2R1, CYP39A1, DDOST, DNAJC1, EPHX1, F10, H6PD, IGF1R, JAK2, LYVE1, NCSTN, NT5E, PDE3B, PEMT, PEX13, SCARB1, SLC16A2, SLC17A5, SLC2A2, SLC7A2, SSR3, TPST1, USO1, ZMPSTE24	274	membrane fraction
GO:0031090	4.169e-02	52.11	71 ABCA5, ACER3, ACP2, ACSL5, AK2, ALG8, ARCN1, B4GALT5, CEPT1, CHMP6, CKAP4, CLPX, COL4A3BP, COPA, COPB1, CRLS1, CYP2R1, CYP39A1, DDOST, DERL1, DHCR24, DNAJC1, DNAJC3, EGFR, EPHX1, ERGIC1, ERP44, FZD5, GALNT7, GCHFR, GOLGA1, GOLIM4, HM13, KMO, LPCAT3, MFSD2A, MTMR2, NCSTN, NPC1, OTC, PEMT, PEX11A, PEX13, RAB33B, RHOU, RNF103, SAR1B, SEC23A, SEC24D, SEC61A1, SERINC5, SGPL1, SLC17A5, SLC25A12, SLC25A19, SLC25A47, SLC26A11, SLC35C1, SSR3, TLR3, TM9SF2, TMEM18, TMEM55A, TPST1, UBXN4, UNC50, USO1, WDR44, YIPF5, ZMPSTE24, ZW10	674	organelle membrane
GO:0044452	4.532e-02	0.6958	4 CDKN2AIP, GAR1, NOP58, RPP40	9	nucleolar part
GO:0005626	4.699e-02	21.96	35 ABCA1, ABCB11, ABCC2, ACP2, ALG2, AMBP, AQP8, ATP8B1, BDKRB1, CKAP4, COPA, CYP2R1, CYP39A1, DDOST, DNAJC1, EPHX1, F10, H6PD, IGF1R, JAK2, LYVE1, NCSTN, NT5E, PDE3B, PEMT, PEX13, SCARB1, SLC16A2, SLC17A5, SLC2A2, SLC7A2, SSR3, TPST1, USO1, ZMPSTE24	284	insoluble fraction

Id	Pvalue	ExpCount	Count	Size	Term
GO:0019842	2.513e-05	4.299	18 AGXT, ALAS1, ALB, C17orf101, C8G, CCBL1, DHTKD1, GLDC, GNMT, MOCOS, P4HA1, PYGL, RBP4, SDSL, SGPL1, SLC46A1, TAT, TTPA	55	vitamin binding
GO:0030170	2.159e-04	1.641	10 AGXT, ALAS1, ALB, CCBL1, GLDC, MOCOS, PYGL, SDSL, SGPL1, TAT	21	pyridoxal phosphate binding
GO:0070279	2.159e-04	1.641	10 AGXT, ALAS1, ALB, CCBL1, GLDC, MOCOS, PYGL, SDSL, SGPL1, TAT	21	vitamin B6 binding
GO:0048037	3.964e-03	6.487	18 AGXT, ALAS1, ALB, ALDH9A1, CCBL1, DHCR24, DHTKD1, GLDC, H6PD, HAO1, HAO2, KMO, MOCOS, PAH, PYGL, SDSL, SGPL1, TAT	83	cofactor binding
GO:0016597	4.746e-03	1.954	9 AGXT, DPYS, GCHFR, GNMT, OTC, PAH, SLC46A1, TAT, TDO2	25	amino acid binding
GO:0003824	4.760e-03	139.9	175 A1CF, ABCA1, ABCA5, ABCB11, ABCC2, ACE2, ACER3, ACOT12, ACP2, ACSL5, ACSS3, ACVR1C, ACVR2A, ADPGK, AFMID, AGXT, AK2, AKR1D1, ALAD, ALAS1, ALDH9A1, ALG2, ALG8, ALKBH1, AMDHD1, ASPG, ATP8B1, B4GALT5, BCKDHB, BLMH, BMP2, BST1, BTRC, C17orf101, C1orf25, CA6, CCBL1, CDC42BPA, CDO1, CEPT1, CLK4, CLPX, COL4A3BP, CPB2, CRLS1, CTBS, CYP2R1, CYP39A1, DBR1, DDOST, DHCR24, DHDPSL, DHTKD1, DPYS, EDEM3, EGFR, ENPP7, EPHA1, EPHX1, ERP44, ETNK2, F10, F2, F9, FBXO4, FH, GALNT7, GAR1, GCH1, GCLM, GLDC, GLO1, GNMT, GPHN, GPLD1, GPN1, H6PD, HAGH, HAL, HAO1, HAO2, HGD, HGF, HHIPL1, HM13, HSDL1, HYI, IGF1R, IHH, IYD, JAK2, KMO, LACTB, LIPC, LPCAT3, LYN, MAP2K5, MASP1, MASP2, MAT1A, MMP13, MOCOS, MSRA, MTAP, MTMR2, NAGA, NAPRT1, NCSTN, NT5E, NUDT12, NUDT19, OTC, P4HA1, PAFAH1B2, PAH, PARP6, PARS2, PCK2, PCSK9, PDE1A, PDE3B, PEMT, PGM3, PIAS1, PIK3C3, PIP5K1C, PLA2G12B, PLAT, PM20D1, POLR3F, PPAPDC1B, PPIB, PPIL3, PRDX4, PROZ, PSMA3, PTPRG, PYGL, QPCT, RHOU, RNF103, RPP40, RPUSD2, SDF2, SDR42E1, SDSL, SENP6, SGPL1, SKIV2L, SSH1, STAB1, STAB2, STK24, STK40, TADA2A, TARSL2, TAT, TDO2, TMEM195, TMEM55A, TOP2B, TPST1, TWISTNB, UBE2CBP, USP20, USP34, USP53, USP54, VAT1, XRCC6BP1, YTHDC2, ZAP70, ZC3H12C, ZC3H12D, ZMPSTE24	1790	catalytic activity
GO:0016829	5.840e-03	5.002	15 ALAD, ALKBH1, BCKDHB, CA6, CCBL1, DHDPSL, FH, GLDC, GLO1, HAL, MOCOS, PCK2, SDSL, SGPL1, TAT	64	lyase activity
GO:0005506	7.462e-03	3.517	12 ALKBH1, AMBP, C17orf101, CDO1, CYP2R1, CYP39A1, HEBP1, NT5E, P4HA1, PAH, TDO2, TMEM195	45	iron ion binding
GO:0031406	9.234e-03	4.143	13 AGXT, ALB, C17orf101, DPYS, GCHFR, GNMT, OTC, P4HA1, PAH, PYGL, SLC46A1, TAT, TDO2	53	carboxylic acid binding
GO:0034185	2.166e-02	0.469	4 ABCA1, LIPC, MAPT, SCARB1	6	apolipoprotein binding
GO:0016491	2.243e-02	16.02	30 AKR1D1, ALDH9A1, ALKBH1, BCKDHB, BMP2, C17orf101, CDO1, CYP2R1, CYP39A1, DHCR24, DHTKD1, GCLM, GLDC, H6PD, HAO1, HAO2, HGD, HSDL1, IYD, KMO, MSRA, P4HA1, PAH, PRDX4, SDR42E1, STAB1, STAB2, TDO2, TMEM195, VAT1	205	oxidoreductase activity
GO:0043176	4.645e-02	3.361	10 AGXT, ALDH9A1, DPYS, GCHFR, GNMT, OTC, PAH, SLC46A1, TAT, TDO2	43	amine binding
GO:0004252	4.645e-02	2.814	9 F10, F2, F9, HGF, MASP1, MASP2, PCSK9, PLAT, PROZ	36	serine-type endopeptidase activity
GO:0008034	4.711e-02	0.9379	5 LIPC, MAPT, SCARB1, STAB1, STAB2	12	lipoprotein binding

Id	Pvalue	ExpCount	Count	Size	Term
04610	1.240e-09	2.191	16 BDKRB1, C5, C8A, C8B, C8G, CPB2, F10, F2, F9, FGB, FGG, MASP1, MASP2, PLAT, SERPINC1, SERPINF2	21	Complement and coagulation cascades
01100	4.927e-02	36.83	53 ACSL5, ACSS3, ADPGK, AFMID, AGXT, AK2, AKR1D1, ALAD, ALAS1, ALDH9A1, ALG2, ALG8, AMDHD1, BCKDHB, BST1, CDO1, CEPT1, CRLS1, DDOST, DHCR24, DPYS, ENPP7, ETNK2, FH, GALNT7, GCH1, GCLM, GLDC, H6PD, HAL, HAO1, HAO2, HGD, HYI, KMO, LIPC, MAT1A, MTAP, MTMR2, NT5E, OTC, P4HA1, PAFAH1B2, PAH, PCK2, PEMT, PIK3C3, PIP5K1C, PLA2G12B, POLR3F, SGPL1, TAT, TDO2	353	Metabolic pathways

No enriched terms

No enriched terms

Entrez genes

A1CFAPOBEC1 complementation factor (ENSG00000148584), score: 0.4 ABCA1ATP-binding cassette, sub-family A (ABC1), member 1 (ENSG00000165029), score: 0.39 ABCA5ATP-binding cassette, sub-family A (ABC1), member 5 (ENSG00000154265), score: -0.51 ABCB11ATP-binding cassette, sub-family B (MDR/TAP), member 11 (ENSG00000073734), score: 0.5 ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ENSG00000023839), score: 0.44 ACE2angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ENSG00000130234), score: 0.57 ACER3alkaline ceramidase 3 (ENSG00000078124), score: 0.48 ACOT12acyl-CoA thioesterase 12 (ENSG00000172497), score: 0.56 ACP2acid phosphatase 2, lysosomal (ENSG00000134575), score: 0.43 ACSL5acyl-CoA synthetase long-chain family member 5 (ENSG00000197142), score: 0.44 ACSS3acyl-CoA synthetase short-chain family member 3 (ENSG00000111058), score: 0.41 ACVR1Cactivin A receptor, type IC (ENSG00000123612), score: 0.44 ACVR2Aactivin A receptor, type IIA (ENSG00000121989), score: 0.53 ADIPOQadiponectin, C1Q and collagen domain containing (ENSG00000181092), score: 0.52 ADPGKADP-dependent glucokinase (ENSG00000159322), score: 0.39 AFMIDarylformamidase (ENSG00000183077), score: 0.43 AGXTalanine-glyoxylate aminotransferase (ENSG00000172482), score: 0.49 AK2adenylate kinase 2 (ENSG00000004455), score: 0.48 AKAP12A kinase (PRKA) anchor protein 12 (ENSG00000131016), score: -0.48 AKR1D1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (ENSG00000122787), score: 0.56 ALADaminolevulinate dehydratase (ENSG00000148218), score: 0.47 ALAS1aminolevulinate, delta-, synthase 1 (ENSG00000023330), score: 0.38 ALBalbumin (ENSG00000163631), score: 0.5 ALDH9A1aldehyde dehydrogenase 9 family, member A1 (ENSG00000143149), score: 0.48 ALG2asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae) (ENSG00000119523), score: 0.57 ALG8asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae) (ENSG00000159063), score: 0.38 ALKBH1alkB, alkylation repair homolog 1 (E. coli) (ENSG00000100601), score: -0.55 AMBPalpha-1-microglobulin/bikunin precursor (ENSG00000106927), score: 0.52 AMDHD1amidohydrolase domain containing 1 (ENSG00000139344), score: 0.57 AMOTL1angiomotin like 1 (ENSG00000166025), score: -0.53 ANK3ankyrin 3, node of Ranvier (ankyrin G) (ENSG00000151150), score: -0.44 ANKRD40ankyrin repeat domain 40 (ENSG00000154945), score: -0.53 AP3M2adaptor-related protein complex 3, mu 2 subunit (ENSG00000070718), score: -0.54 AQP8aquaporin 8 (ENSG00000103375), score: 0.55 ARCN1archain 1 (ENSG00000095139), score: 0.48 ARHGEF3Rho guanine nucleotide exchange factor (GEF) 3 (ENSG00000163947), score: -0.46 ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ENSG00000153317), score: -0.45 ASPGasparaginase homolog (S. cerevisiae) (ENSG00000166183), score: 0.47 ATP8B1ATPase, aminophospholipid transporter, class I, type 8B, member 1 (ENSG00000081923), score: 0.48 ATRNattractin (ENSG00000088812), score: 0.42 AVPR1Aarginine vasopressin receptor 1A (ENSG00000166148), score: 0.64 AXIN1axin 1 (ENSG00000103126), score: 0.49 B4GALT5UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (ENSG00000158470), score: -0.48 BAT2L1HLA-B associated transcript 2-like 1 (ENSG00000130723), score: -0.45 BBS2Bardet-Biedl syndrome 2 (ENSG00000125124), score: -0.5 BCKDHBbranched chain keto acid dehydrogenase E1, beta polypeptide (ENSG00000083123), score: 0.42 BDKRB1bradykinin receptor B1 (ENSG00000100739), score: 0.44 BLMHbleomycin hydrolase (ENSG00000108578), score: 0.51 BMP2bone morphogenetic protein 2 (ENSG00000125845), score: 0.5 BST1bone marrow stromal cell antigen 1 (ENSG00000109743), score: 0.43 BTRCbeta-transducin repeat containing (ENSG00000166167), score: -0.61 C17orf101chromosome 17 open reading frame 101 (ENSG00000181396), score: 0.38 C18orf8chromosome 18 open reading frame 8 (ENSG00000141452), score: 0.43 C1orf25chromosome 1 open reading frame 25 (ENSG00000121486), score: 0.38 C20orf4chromosome 20 open reading frame 4 (ENSG00000131043), score: 0.43 C4orf34chromosome 4 open reading frame 34 (ENSG00000163683), score: 0.41 C5complement component 5 (ENSG00000106804), score: 0.52 C6orf62chromosome 6 open reading frame 62 (ENSG00000112308), score: 0.4 C8Acomplement component 8, alpha polypeptide (ENSG00000157131), score: 0.46 C8Bcomplement component 8, beta polypeptide (ENSG00000021852), score: 0.53 C8Gcomplement component 8, gamma polypeptide (ENSG00000176919), score: 0.39 CA6carbonic anhydrase VI (ENSG00000131686), score: 0.82 CAMSAP1L1calmodulin regulated spectrin-associated protein 1-like 1 (ENSG00000118200), score: -0.45 CBY1chibby homolog 1 (Drosophila) (ENSG00000100211), score: -0.5 CCBL1cysteine conjugate-beta lyase, cytoplasmic (ENSG00000171097), score: 0.53 CCDC127coiled-coil domain containing 127 (ENSG00000164366), score: -0.44 CCND3cyclin D3 (ENSG00000112576), score: -0.45 CD34CD34 molecule (ENSG00000174059), score: -0.46 CD82CD82 molecule (ENSG00000085117), score: 0.56 CD86CD86 molecule (ENSG00000114013), score: 0.53 CDC42BPACDC42 binding protein kinase alpha (DMPK-like) (ENSG00000143776), score: -0.69 CDH1cadherin 1, type 1, E-cadherin (epithelial) (ENSG00000039068), score: 0.39 CDKN2AIPCDKN2A interacting protein (ENSG00000168564), score: -0.49 CDO1cysteine dioxygenase, type I (ENSG00000129596), score: 0.43 CEPT1choline/ethanolamine phosphotransferase 1 (ENSG00000134255), score: 0.46 CHMP6chromatin modifying protein 6 (ENSG00000176108), score: 0.44 CIAO1cytosolic iron-sulfur protein assembly 1 (ENSG00000144021), score: 0.43 CISHcytokine inducible SH2-containing protein (ENSG00000114737), score: 0.5 CKAP4cytoskeleton-associated protein 4 (ENSG00000136026), score: -0.53 CKAP5cytoskeleton associated protein 5 (ENSG00000175216), score: -0.44 CLDN1claudin 1 (ENSG00000163347), score: 0.5 CLIP1CAP-GLY domain containing linker protein 1 (ENSG00000130779), score: -0.45 CLK4CDC-like kinase 4 (ENSG00000113240), score: -0.51 CLPXClpX caseinolytic peptidase X homolog (E. coli) (ENSG00000166855), score: 0.48 COL4A3BPcollagen, type IV, alpha 3 (Goodpasture antigen) binding protein (ENSG00000113163), score: 0.48 COPAcoatomer protein complex, subunit alpha (ENSG00000122218), score: -0.45 COPB1coatomer protein complex, subunit beta 1 (ENSG00000129083), score: 0.4 CPB2carboxypeptidase B2 (plasma) (ENSG00000080618), score: 0.52 CREG1cellular repressor of E1A-stimulated genes 1 (ENSG00000143162), score: 0.44 CRLS1cardiolipin synthase 1 (ENSG00000088766), score: 0.46 CTBSchitobiase, di-N-acetyl- (ENSG00000117151), score: 0.53 CTCFCCCTC-binding factor (zinc finger protein) (ENSG00000102974), score: -0.47 CXXC5CXXC finger 5 (ENSG00000171604), score: -0.53 CYP2R1cytochrome P450, family 2, subfamily R, polypeptide 1 (ENSG00000186104), score: 0.5 CYP39A1cytochrome P450, family 39, subfamily A, polypeptide 1 (ENSG00000146233), score: 0.56 DBR1debranching enzyme homolog 1 (S. cerevisiae) (ENSG00000138231), score: 0.38 DDOSTdolichyl-diphosphooligosaccharide--protein glycosyltransferase (ENSG00000244038), score: 0.52 DENND1BDENN/MADD domain containing 1B (ENSG00000213047), score: 0.42 DENND5ADENN/MADD domain containing 5A (ENSG00000184014), score: -0.55 DERL1Der1-like domain family, member 1 (ENSG00000136986), score: 0.48 DHCR2424-dehydrocholesterol reductase (ENSG00000116133), score: 0.41 DHDPSLdihydrodipicolinate synthase-like, mitochondrial (ENSG00000241935), score: 0.39 DHTKD1dehydrogenase E1 and transketolase domain containing 1 (ENSG00000181192), score: 0.59 DIRC2disrupted in renal carcinoma 2 (ENSG00000138463), score: 0.4 DNAJC1DnaJ (Hsp40) homolog, subfamily C, member 1 (ENSG00000136770), score: 0.4 DNAJC22DnaJ (Hsp40) homolog, subfamily C, member 22 (ENSG00000178401), score: 0.39 DNAJC3DnaJ (Hsp40) homolog, subfamily C, member 3 (ENSG00000102580), score: 0.39 DNTTIP1deoxynucleotidyltransferase, terminal, interacting protein 1 (ENSG00000101457), score: 0.38 DOCK9dedicator of cytokinesis 9 (ENSG00000088387), score: -0.44 DPYSdihydropyrimidinase (ENSG00000147647), score: 0.39 EDARectodysplasin A receptor (ENSG00000135960), score: 0.49 EDEM3ER degradation enhancer, mannosidase alpha-like 3 (ENSG00000116406), score: 0.48 EGFRepidermal growth factor receptor (ENSG00000146648), score: 0.44 ENPP7ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENSG00000182156), score: 0.4 EPB41L2erythrocyte membrane protein band 4.1-like 2 (ENSG00000079819), score: -0.45 EPB41L4Berythrocyte membrane protein band 4.1 like 4B (ENSG00000095203), score: 0.41 EPHA1EPH receptor A1 (ENSG00000146904), score: 0.48 EPHX1epoxide hydrolase 1, microsomal (xenobiotic) (ENSG00000143819), score: 0.44 ERGIC1endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 (ENSG00000113719), score: 0.52 ERLEC1endoplasmic reticulum lectin 1 (ENSG00000068912), score: 0.41 ERP44endoplasmic reticulum protein 44 (ENSG00000023318), score: 0.42 ESR1estrogen receptor 1 (ENSG00000091831), score: 0.55 ESRP2epithelial splicing regulatory protein 2 (ENSG00000103067), score: 0.41 ETNK2ethanolamine kinase 2 (ENSG00000143845), score: 0.47 EXOC8exocyst complex component 8 (ENSG00000116903), score: 0.38 F10coagulation factor X (ENSG00000126218), score: 0.58 F2coagulation factor II (thrombin) (ENSG00000180210), score: 0.51 F9coagulation factor IX (ENSG00000101981), score: 0.5 FAF2Fas associated factor family member 2 (ENSG00000113194), score: 0.47 FAM173Bfamily with sequence similarity 173, member B (ENSG00000150756), score: -0.45 FAM20Afamily with sequence similarity 20, member A (ENSG00000108950), score: 0.42 FAM3Cfamily with sequence similarity 3, member C (ENSG00000196937), score: -0.66 FBXO4F-box protein 4 (ENSG00000151876), score: 0.41 FETUBfetuin B (ENSG00000090512), score: 0.64 FGBfibrinogen beta chain (ENSG00000171564), score: 0.46 FGF19fibroblast growth factor 19 (ENSG00000162344), score: 0.67 FGGfibrinogen gamma chain (ENSG00000171557), score: 0.48 FHfumarate hydratase (ENSG00000091483), score: 0.39 FN1fibronectin 1 (ENSG00000115414), score: 0.5 FSTfollistatin (ENSG00000134363), score: 0.41 FZD5frizzled homolog 5 (Drosophila) (ENSG00000163251), score: 0.46 GALNT7UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) (ENSG00000109586), score: -0.44 GAR1GAR1 ribonucleoprotein homolog (yeast) (ENSG00000109534), score: 0.4 GAS2growth arrest-specific 2 (ENSG00000148935), score: 0.4 GAS6growth arrest-specific 6 (ENSG00000183087), score: -0.45 GCH1GTP cyclohydrolase 1 (ENSG00000131979), score: 0.44 GCHFRGTP cyclohydrolase I feedback regulator (ENSG00000137880), score: 0.43 GCLMglutamate-cysteine ligase, modifier subunit (ENSG00000023909), score: 0.51 GDF2growth differentiation factor 2 (ENSG00000128802), score: 0.39 GLDCglycine dehydrogenase (decarboxylating) (ENSG00000178445), score: 0.38 GLO1glyoxalase I (ENSG00000124767), score: 0.43 GNMTglycine N-methyltransferase (ENSG00000124713), score: 0.57 GOLGA1golgin A1 (ENSG00000136935), score: -0.55 GOLIM4golgi integral membrane protein 4 (ENSG00000173905), score: 0.42 GPHNgephyrin (ENSG00000171723), score: 0.48 GPLD1glycosylphosphatidylinositol specific phospholipase D1 (ENSG00000112293), score: 0.62 GPN1GPN-loop GTPase 1 (ENSG00000198522), score: 0.43 GPR132G protein-coupled receptor 132 (ENSG00000183484), score: 0.66 GPR56G protein-coupled receptor 56 (ENSG00000205336), score: -0.53 H6PDhexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) (ENSG00000049239), score: 0.47 HAGHhydroxyacylglutathione hydrolase (ENSG00000063854), score: 0.4 HALhistidine ammonia-lyase (ENSG00000084110), score: 0.55 HAO1hydroxyacid oxidase (glycolate oxidase) 1 (ENSG00000101323), score: 0.44 HAO2hydroxyacid oxidase 2 (long chain) (ENSG00000116882), score: 0.45 HEBP1heme binding protein 1 (ENSG00000013583), score: 0.54 HGDhomogentisate 1,2-dioxygenase (ENSG00000113924), score: 0.42 HGFhepatocyte growth factor (hepapoietin A; scatter factor) (ENSG00000019991), score: 0.44 HHIPL1HHIP-like 1 (ENSG00000182218), score: 0.44 HM13histocompatibility (minor) 13 (ENSG00000101294), score: 0.48 HNF4Ghepatocyte nuclear factor 4, gamma (ENSG00000164749), score: 0.43 HPXhemopexin (ENSG00000110169), score: 0.49 HRGhistidine-rich glycoprotein (ENSG00000113905), score: 0.46 HSDL1hydroxysteroid dehydrogenase like 1 (ENSG00000103160), score: -0.45 HTThuntingtin (ENSG00000197386), score: -0.45 HYIhydroxypyruvate isomerase (putative) (ENSG00000178922), score: 0.41 IBTKinhibitor of Bruton agammaglobulinemia tyrosine kinase (ENSG00000005700), score: 0.45 IGF1Rinsulin-like growth factor 1 receptor (ENSG00000140443), score: -0.46 IGFBP1insulin-like growth factor binding protein 1 (ENSG00000146678), score: 0.46 IHHIndian hedgehog (ENSG00000163501), score: 0.42 IL17RAinterleukin 17 receptor A (ENSG00000177663), score: 0.42 IL5RAinterleukin 5 receptor, alpha (ENSG00000091181), score: 0.64 IQCB1IQ motif containing B1 (ENSG00000173226), score: -0.55 ISM1isthmin 1 homolog (zebrafish) (ENSG00000101230), score: 0.44 ITGA4integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ENSG00000115232), score: 0.54 IYDiodotyrosine deiodinase (ENSG00000009765), score: 0.65 JAK2Janus kinase 2 (ENSG00000096968), score: -0.48 KCTD6potassium channel tetramerisation domain containing 6 (ENSG00000168301), score: 0.55 KIAA0664KIAA0664 (ENSG00000132361), score: 0.39 KIAA1432KIAA1432 (ENSG00000107036), score: 0.42 KLHL25kelch-like 25 (Drosophila) (ENSG00000183655), score: 0.44 KLHL5kelch-like 5 (Drosophila) (ENSG00000109790), score: -0.56 KLHL7kelch-like 7 (Drosophila) (ENSG00000122550), score: -0.47 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (ENSG00000117009), score: 0.44 LACTBlactamase, beta (ENSG00000103642), score: 0.46 LAMB3laminin, beta 3 (ENSG00000196878), score: 0.52 LEAP2liver expressed antimicrobial peptide 2 (ENSG00000164406), score: 0.48 LECT2leukocyte cell-derived chemotaxin 2 (ENSG00000145826), score: 0.65 LGR5leucine-rich repeat-containing G protein-coupled receptor 5 (ENSG00000139292), score: 0.43 LIPClipase, hepatic (ENSG00000166035), score: 0.54 LOC100292021similar to thioredoxin peroxidase (ENSG00000123131), score: 0.5 LPCAT3lysophosphatidylcholine acyltransferase 3 (ENSG00000111684), score: 0.44 LRIG3leucine-rich repeats and immunoglobulin-like domains 3 (ENSG00000139263), score: 0.64 LRRC15leucine rich repeat containing 15 (ENSG00000172061), score: 0.89 LRRC31leucine rich repeat containing 31 (ENSG00000114248), score: 0.77 LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog (ENSG00000147507), score: 0.41 LYVE1lymphatic vessel endothelial hyaluronan receptor 1 (ENSG00000133800), score: 0.44 MAP2K5mitogen-activated protein kinase kinase 5 (ENSG00000137764), score: -0.51 MAPTmicrotubule-associated protein tau (ENSG00000186868), score: -0.44 MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (ENSG00000127241), score: 0.42 MASP2mannan-binding lectin serine peptidase 2 (ENSG00000009724), score: 0.51 MAT1Amethionine adenosyltransferase I, alpha (ENSG00000151224), score: 0.53 MATN1matrilin 1, cartilage matrix protein (ENSG00000162510), score: 0.44 MBNL2muscleblind-like 2 (Drosophila) (ENSG00000139793), score: -0.57 MFSD2Amajor facilitator superfamily domain containing 2A (ENSG00000168389), score: 0.38 MKLN1muskelin 1, intracellular mediator containing kelch motifs (ENSG00000128585), score: 0.58 MLLT3myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (ENSG00000171843), score: -0.48 MMP13matrix metallopeptidase 13 (collagenase 3) (ENSG00000137745), score: 0.72 MOCOSmolybdenum cofactor sulfurase (ENSG00000075643), score: 0.45 MORN4MORN repeat containing 4 (ENSG00000171160), score: -0.5 MRPS18Amitochondrial ribosomal protein S18A (ENSG00000096080), score: 0.44 MRPS30mitochondrial ribosomal protein S30 (ENSG00000112996), score: 0.47 MSRAmethionine sulfoxide reductase A (ENSG00000175806), score: 0.38 MTA1metastasis associated 1 (ENSG00000182979), score: -0.45 MTAPmethylthioadenosine phosphorylase (ENSG00000099810), score: 0.51 MTMR2myotubularin related protein 2 (ENSG00000087053), score: -0.63 MTTPmicrosomal triglyceride transfer protein (ENSG00000138823), score: 0.48 MYNNmyoneurin (ENSG00000085274), score: 0.42 NAGAN-acetylgalactosaminidase, alpha- (ENSG00000198951), score: 0.5 NAPRT1nicotinate phosphoribosyltransferase domain containing 1 (ENSG00000147813), score: 0.38 NCSTNnicastrin (ENSG00000162736), score: 0.41 NOP58NOP58 ribonucleoprotein homolog (yeast) (ENSG00000055044), score: 0.55 NPC1Niemann-Pick disease, type C1 (ENSG00000141458), score: 0.46 NR5A2nuclear receptor subfamily 5, group A, member 2 (ENSG00000116833), score: 0.4 NT5E5'-nucleotidase, ecto (CD73) (ENSG00000135318), score: 0.64 NUDT12nudix (nucleoside diphosphate linked moiety X)-type motif 12 (ENSG00000112874), score: 0.4 NUDT19nudix (nucleoside diphosphate linked moiety X)-type motif 19 (ENSG00000213965), score: 0.47 OIT3oncoprotein induced transcript 3 (ENSG00000138315), score: 0.54 ONECUT1one cut homeobox 1 (ENSG00000169856), score: 0.59 OTCornithine carbamoyltransferase (ENSG00000036473), score: 0.66 P2RY2purinergic receptor P2Y, G-protein coupled, 2 (ENSG00000175591), score: 0.39 P4HA1prolyl 4-hydroxylase, alpha polypeptide I (ENSG00000122884), score: 0.46 PAFAH1B2platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) (ENSG00000168092), score: -0.45 PAHphenylalanine hydroxylase (ENSG00000171759), score: 0.42 PALB2partner and localizer of BRCA2 (ENSG00000083093), score: 0.39 PAQR9progestin and adipoQ receptor family member IX (ENSG00000188582), score: 0.41 PARP6poly (ADP-ribose) polymerase family, member 6 (ENSG00000137817), score: -0.53 PARS2prolyl-tRNA synthetase 2, mitochondrial (putative) (ENSG00000162396), score: 0.39 PARVGparvin, gamma (ENSG00000138964), score: 0.39 PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial) (ENSG00000100889), score: 0.51 PCSK9proprotein convertase subtilisin/kexin type 9 (ENSG00000169174), score: 0.41 PDE1Aphosphodiesterase 1A, calmodulin-dependent (ENSG00000115252), score: -0.46 PDE3Bphosphodiesterase 3B, cGMP-inhibited (ENSG00000152270), score: 0.41 PEMTphosphatidylethanolamine N-methyltransferase (ENSG00000133027), score: 0.49 PEX11Aperoxisomal biogenesis factor 11 alpha (ENSG00000166821), score: 0.56 PEX13peroxisomal biogenesis factor 13 (ENSG00000162928), score: 0.4 PGM3phosphoglucomutase 3 (ENSG00000013375), score: 0.49 PHIPpleckstrin homology domain interacting protein (ENSG00000146247), score: -0.45 PIAS1protein inhibitor of activated STAT, 1 (ENSG00000033800), score: -0.57 PIK3C3phosphoinositide-3-kinase, class 3 (ENSG00000078142), score: -0.5 PIK3IP1phosphoinositide-3-kinase interacting protein 1 (ENSG00000100100), score: -0.5 PIP5K1Cphosphatidylinositol-4-phosphate 5-kinase, type I, gamma (ENSG00000186111), score: -0.47 PLA2G12Bphospholipase A2, group XIIB (ENSG00000138308), score: 0.45 PLATplasminogen activator, tissue (ENSG00000104368), score: -0.48 PM20D1peptidase M20 domain containing 1 (ENSG00000162877), score: 0.54 POLR3Fpolymerase (RNA) III (DNA directed) polypeptide F, 39 kDa (ENSG00000132664), score: 0.52 PPAPDC1Bphosphatidic acid phosphatase type 2 domain containing 1B (ENSG00000147535), score: 0.41 PPIBpeptidylprolyl isomerase B (cyclophilin B) (ENSG00000166794), score: 0.39 PPIL3peptidylprolyl isomerase (cyclophilin)-like 3 (ENSG00000240344), score: 0.43 PPP6R2protein phosphatase 6, regulatory subunit 2 (ENSG00000100239), score: 0.58 PROZprotein Z, vitamin K-dependent plasma glycoprotein (ENSG00000126231), score: 0.57 PRRG1proline rich Gla (G-carboxyglutamic acid) 1 (ENSG00000130962), score: 0.39 PSMA3proteasome (prosome, macropain) subunit, alpha type, 3 (ENSG00000100567), score: 0.4 PTPRGprotein tyrosine phosphatase, receptor type, G (ENSG00000144724), score: 0.38 PYGLphosphorylase, glycogen, liver (ENSG00000100504), score: 0.4 QPCTglutaminyl-peptide cyclotransferase (ENSG00000115828), score: 0.52 RAB20RAB20, member RAS oncogene family (ENSG00000139832), score: 0.42 RAB33BRAB33B, member RAS oncogene family (ENSG00000172007), score: 0.44 RALGAPA1Ral GTPase activating protein, alpha subunit 1 (catalytic) (ENSG00000174373), score: -0.51 RANBP10RAN binding protein 10 (ENSG00000141084), score: 0.56 RASA2RAS p21 protein activator 2 (ENSG00000155903), score: -0.47 RBP4retinol binding protein 4, plasma (ENSG00000138207), score: 0.49 RGS2regulator of G-protein signaling 2, 24kDa (ENSG00000116741), score: -0.49 RHOUras homolog gene family, member U (ENSG00000116574), score: 0.43 RLFrearranged L-myc fusion (ENSG00000117000), score: -0.45 RNF103ring finger protein 103 (ENSG00000239305), score: 0.4 ROBO1roundabout, axon guidance receptor, homolog 1 (Drosophila) (ENSG00000169855), score: -0.45 RPP40ribonuclease P/MRP 40kDa subunit (ENSG00000124787), score: 0.46 RPUSD2RNA pseudouridylate synthase domain containing 2 (ENSG00000166133), score: 0.4 RRAGDRas-related GTP binding D (ENSG00000025039), score: -0.47 SAMD8sterile alpha motif domain containing 8 (ENSG00000156671), score: -0.47 SAR1BSAR1 homolog B (S. cerevisiae) (ENSG00000152700), score: 0.48 SASH1SAM and SH3 domain containing 1 (ENSG00000111961), score: -0.46 SCARB1scavenger receptor class B, member 1 (ENSG00000073060), score: 0.47 SCUBE3signal peptide, CUB domain, EGF-like 3 (ENSG00000146197), score: 0.43 SDC2syndecan 2 (ENSG00000169439), score: 0.44 SDF2stromal cell-derived factor 2 (ENSG00000132581), score: 0.4 SDR42E1short chain dehydrogenase/reductase family 42E, member 1 (ENSG00000184860), score: 0.53 SDSLserine dehydratase-like (ENSG00000139410), score: 0.42 SEBOXSEBOX homeobox (ENSG00000109072), score: 0.45 SEC23ASec23 homolog A (S. cerevisiae) (ENSG00000100934), score: 0.42 SEC24DSEC24 family, member D (S. cerevisiae) (ENSG00000150961), score: 0.41 SEC61A1Sec61 alpha 1 subunit (S. cerevisiae) (ENSG00000058262), score: 0.41 SENP6SUMO1/sentrin specific peptidase 6 (ENSG00000112701), score: -0.46 SERINC5serine incorporator 5 (ENSG00000164300), score: 0.53 SERPINA10serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 (ENSG00000140093), score: 0.51 SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 1 (ENSG00000117601), score: 0.51 SERPINF2serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (ENSG00000167711), score: 0.44 SETBP1SET binding protein 1 (ENSG00000152217), score: -0.44 SETD5SET domain containing 5 (ENSG00000168137), score: -0.54 SFRS18splicing factor, arginine/serine-rich 18 (ENSG00000132424), score: -0.47 SGCEsarcoglycan, epsilon (ENSG00000127990), score: -0.53 SGPL1sphingosine-1-phosphate lyase 1 (ENSG00000166224), score: 0.43 SH3GLB2SH3-domain GRB2-like endophilin B2 (ENSG00000148341), score: -0.48 SKIV2Lsuperkiller viralicidic activity 2-like (S. cerevisiae) (ENSG00000204351), score: 0.43 SKP2S-phase kinase-associated protein 2 (p45) (ENSG00000145604), score: 0.44 SLC16A2solute carrier family 16, member 2 (monocarboxylic acid transporter 8) (ENSG00000147100), score: 0.38 SLC17A5solute carrier family 17 (anion/sugar transporter), member 5 (ENSG00000119899), score: 0.54 SLC25A12solute carrier family 25 (mitochondrial carrier, Aralar), member 12 (ENSG00000115840), score: -0.45 SLC25A19solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 (ENSG00000125454), score: -0.46 SLC25A47solute carrier family 25, member 47 (ENSG00000140107), score: 0.44 SLC26A11solute carrier family 26, member 11 (ENSG00000181045), score: 0.4 SLC2A2solute carrier family 2 (facilitated glucose transporter), member 2 (ENSG00000163581), score: 0.39 SLC2A9solute carrier family 2 (facilitated glucose transporter), member 9 (ENSG00000109667), score: 0.43 SLC30A1solute carrier family 30 (zinc transporter), member 1 (ENSG00000170385), score: 0.49 SLC30A10solute carrier family 30, member 10 (ENSG00000196660), score: 0.53 SLC30A7solute carrier family 30 (zinc transporter), member 7 (ENSG00000162695), score: 0.45 SLC31A1solute carrier family 31 (copper transporters), member 1 (ENSG00000136868), score: 0.52 SLC35C1solute carrier family 35, member C1 (ENSG00000181830), score: 0.42 SLC38A4solute carrier family 38, member 4 (ENSG00000139209), score: 0.51 SLC39A9solute carrier family 39 (zinc transporter), member 9 (ENSG00000029364), score: 0.73 SLC45A3solute carrier family 45, member 3 (ENSG00000158715), score: 0.71 SLC46A1solute carrier family 46 (folate transporter), member 1 (ENSG00000076351), score: 0.57 SLC7A2solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 (ENSG00000003989), score: 0.46 SLC7A6solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (ENSG00000103064), score: -0.56 SNX24sorting nexin 24 (ENSG00000064652), score: 0.39 SPIRE1spire homolog 1 (Drosophila) (ENSG00000134278), score: -0.52 SPP2secreted phosphoprotein 2, 24kDa (ENSG00000072080), score: 0.52 SRSF4serine/arginine-rich splicing factor 4 (ENSG00000116350), score: -0.46 SRSF5serine/arginine-rich splicing factor 5 (ENSG00000100650), score: -0.44 SSH1slingshot homolog 1 (Drosophila) (ENSG00000084112), score: -0.47 SSR3signal sequence receptor, gamma (translocon-associated protein gamma) (ENSG00000114850), score: 0.42 STAB1stabilin 1 (ENSG00000010327), score: 0.46 STAB2stabilin 2 (ENSG00000136011), score: 0.43 STARD5StAR-related lipid transfer (START) domain containing 5 (ENSG00000172345), score: 0.63 STK24serine/threonine kinase 24 (ENSG00000102572), score: -0.45 STK40serine/threonine kinase 40 (ENSG00000196182), score: 0.43 TACC1transforming, acidic coiled-coil containing protein 1 (ENSG00000147526), score: -0.5 TADA2Atranscriptional adaptor 2A (ENSG00000108264), score: -0.47 TAPT1transmembrane anterior posterior transformation 1 (ENSG00000169762), score: 0.39 TARSL2threonyl-tRNA synthetase-like 2 (ENSG00000185418), score: -0.58 TATtyrosine aminotransferase (ENSG00000198650), score: 0.52 TBCCtubulin folding cofactor C (ENSG00000124659), score: 0.41 TCF12transcription factor 12 (ENSG00000140262), score: 0.4 TDO2tryptophan 2,3-dioxygenase (ENSG00000151790), score: 0.45 TLN2talin 2 (ENSG00000171914), score: -0.48 TLR3toll-like receptor 3 (ENSG00000164342), score: 0.8 TM4SF4transmembrane 4 L six family member 4 (ENSG00000169903), score: 0.47 TM9SF2transmembrane 9 superfamily member 2 (ENSG00000125304), score: 0.38 TMEM135transmembrane protein 135 (ENSG00000166575), score: 0.39 TMEM18transmembrane protein 18 (ENSG00000151353), score: 0.49 TMEM195transmembrane protein 195 (ENSG00000187546), score: 0.5 TMEM20transmembrane protein 20 (ENSG00000176273), score: 0.54 TMEM33transmembrane protein 33 (ENSG00000109133), score: 0.51 TMEM55Atransmembrane protein 55A (ENSG00000155099), score: -0.51 TOM1L2target of myb1-like 2 (chicken) (ENSG00000175662), score: -0.54 TOP2Btopoisomerase (DNA) II beta 180kDa (ENSG00000077097), score: -0.46 TP53BP1tumor protein p53 binding protein 1 (ENSG00000067369), score: -0.47 TPST1tyrosylprotein sulfotransferase 1 (ENSG00000169902), score: 0.65 TRABDTraB domain containing (ENSG00000170638), score: 0.4 TRAM2translocation associated membrane protein 2 (ENSG00000065308), score: 0.42 TSKUtsukushi small leucine rich proteoglycan homolog (Xenopus laevis) (ENSG00000182704), score: 0.41 TTC13tetratricopeptide repeat domain 13 (ENSG00000143643), score: 0.39 TTC21Btetratricopeptide repeat domain 21B (ENSG00000123607), score: -0.58 TTC33tetratricopeptide repeat domain 33 (ENSG00000113638), score: -0.45 TTC36tetratricopeptide repeat domain 36 (ENSG00000172425), score: 0.42 TTPAtocopherol (alpha) transfer protein (ENSG00000137561), score: 0.62 TWISTNBTWIST neighbor (ENSG00000105849), score: 0.44 TWSG1twisted gastrulation homolog 1 (Drosophila) (ENSG00000128791), score: -0.66 TXNDC15thioredoxin domain containing 15 (ENSG00000113621), score: 0.42 UBE2CBPubiquitin-conjugating enzyme E2C binding protein (ENSG00000118420), score: 0.39 UBXN4UBX domain protein 4 (ENSG00000144224), score: 0.47 UIMC1ubiquitin interaction motif containing 1 (ENSG00000087206), score: -0.46 UNC50unc-50 homolog (C. elegans) (ENSG00000115446), score: 0.43 USO1USO1 vesicle docking protein homolog (yeast) (ENSG00000138768), score: 0.41 USP20ubiquitin specific peptidase 20 (ENSG00000136878), score: -0.52 USP34ubiquitin specific peptidase 34 (ENSG00000115464), score: -0.45 USP53ubiquitin specific peptidase 53 (ENSG00000145390), score: -0.51 USP54ubiquitin specific peptidase 54 (ENSG00000166348), score: -0.47 VASH1vasohibin 1 (ENSG00000071246), score: -0.44 VAT1vesicle amine transport protein 1 homolog (T. californica) (ENSG00000108828), score: 0.59 VGLL1vestigial like 1 (Drosophila) (ENSG00000102243), score: 0.43 VSIG4V-set and immunoglobulin domain containing 4 (ENSG00000155659), score: 0.51 WDR3WD repeat domain 3 (ENSG00000065183), score: 0.44 WDR44WD repeat domain 44 (ENSG00000131725), score: 0.41 XKR9XK, Kell blood group complex subunit-related family, member 9 (ENSG00000221947), score: 0.64 XRCC6BP1XRCC6 binding protein 1 (ENSG00000166896), score: 0.51 YIPF5Yip1 domain family, member 5 (ENSG00000145817), score: 0.47 YTHDC2YTH domain containing 2 (ENSG00000047188), score: -0.47 ZAP70zeta-chain (TCR) associated protein kinase 70kDa (ENSG00000115085), score: 0.46 ZBTB49zinc finger and BTB domain containing 49 (ENSG00000168826), score: -0.49 ZC3H12Czinc finger CCCH-type containing 12C (ENSG00000149289), score: -0.56 ZC3H12Dzinc finger CCCH-type containing 12D (ENSG00000178199), score: 1 ZFYVE1zinc finger, FYVE domain containing 1 (ENSG00000165861), score: 0.41 ZMPSTE24zinc metallopeptidase (STE24 homolog, S. cerevisiae) (ENSG00000084073), score: 0.44 ZNF326zinc finger protein 326 (ENSG00000162664), score: 0.49 ZNF462zinc finger protein 462 (ENSG00000148143), score: -0.48 ZNHIT6zinc finger, HIT type 6 (ENSG00000117174), score: -0.53 ZW10ZW10, kinetochore associated, homolog (Drosophila) (ENSG00000086827), score: 0.4

Non-Entrez genes

ENSG00000143819Unknown, score: 0.41

Id	species	tissue	sex	individual
mml_lv_m_ca1	mml	lv	m	_
oan_lv_f_ca1	oan	lv	f	_
oan_lv_m_ca1	oan	lv	m	_