Under-expression is coded with green,
over-expression with red color.
transition metal ion transport
The directed movement of transition metal ions into, out of, within or between cells by means of some external agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
cell activation
A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
adaptive immune response
An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).
immune effector process
Any process of the immune system that occurs as part of an immune response.
activation of immune response
Any process that initiates an immune response.
immune system process
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
leukocyte mediated immunity
Any process involved in the carrying out of an immune response by a leukocyte.
lymphocyte mediated immunity
Any process involved in the carrying out of an immune response by a lymphocyte.
humoral immune response mediated by circulating immunoglobulin
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies). An example of this is the adaptive immune response found in Mus musculus.
acute inflammatory response
Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
activation of plasma proteins involved in acute inflammatory response
Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
regulation of leukocyte activation
Any process that modulates the frequency, rate, or extent of leukocyte activation.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
regulation of immune effector process
Any process that modulates the frequency, rate, or extent of an immune effector process.
defense response
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
blood coagulation
The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
carbohydrate metabolic process
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
monosaccharide metabolic process
The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
glucose metabolic process
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
alcohol metabolic process
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
organic acid metabolic process
The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
oxidation reduction
The process of removal or addition of one or more electrons with or without the concomitant removal or addition of a proton or protons.
protein maturation by peptide bond cleavage
The hydrolysis of a peptide bond or bonds within a protein as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein.
cellular amino acid and derivative metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.
cellular amino acid metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.
glycine metabolic process
The chemical reactions and pathways involving glycine, aminoethanoic acid.
cellular amino acid derivative metabolic process
The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.
cellular biogenic amine metabolic process
The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
lipid metabolic process
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
steroid biosynthetic process
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
bile acid biosynthetic process
The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.
cellular aromatic compound metabolic process
The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
coenzyme metabolic process
The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
transport
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.
ion transport
The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.
cation transport
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.
metal ion transport
The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.
response to stress
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
inflammatory response
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
complement activation, alternative pathway
Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
complement activation, classical pathway
Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.
humoral immune response
An immune response mediated through a body fluid.
hemostasis
The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
steroid metabolic process
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
cholesterol metabolic process
The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
bile acid metabolic process
The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
androgen metabolic process
The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
negative regulation of coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.
lipid biosynthetic process
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
catabolic process
The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
biosynthetic process
The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
cellular amino acid catabolic process
The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.
serine family amino acid metabolic process
The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
serine family amino acid catabolic process
The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
aromatic amino acid family metabolic process
The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
aromatic amino acid family catabolic process
The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
amine metabolic process
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
amine catabolic process
The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
response to external stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
response to biotic stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
response to wounding
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
response to organic substance
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
gene expression
The process by which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.
regulation of hormone levels
Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.
organic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.
organic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.
immunoglobulin mediated immune response
An immune response mediated by immunoglobulins, whether cell-bound or in solution.
sterol metabolic process
The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
protein processing
Any protein maturation process achieved by the cleavage of peptide bonds.
hexose metabolic process
The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
aromatic compound catabolic process
The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
B cell mediated immunity
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
carboxylic acid metabolic process
The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
regulation of blood coagulation
Any process that modulates the frequency, rate or extent of blood coagulation.
negative regulation of blood coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation.
regulation of response to external stimulus
Any process that modulates the frequency, rate or extent of a response to an external stimulus.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
monocarboxylic acid metabolic process
The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
cellular nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
cellular hormone metabolic process
The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells.
wound healing
The series of events that restore integrity to a damaged tissue, following an injury.
T cell activation
The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
cellular ketone metabolic process
The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
response to chemical stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
hormone metabolic process
The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
oxoacid metabolic process
The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
cellular amine metabolic process
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
cellular catabolic process
The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
cellular biosynthetic process
The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
cellular carbohydrate metabolic process
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
small molecule metabolic process
The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass.
small molecule catabolic process
The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.
small molecule biosynthetic process
The chemical reactions and pathways resulting in the formation of small molecules, any monomeric molecule of small relative molecular mass.
innate immune response
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
leukocyte activation
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
carboxylic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
carboxylic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
lymphocyte activation
A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
negative regulation of biological process
Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
coagulation
The process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
regulation of coagulation
Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
regulation of T cell activation
Any process that modulates the frequency, rate or extent of T cell activation.
regulation of cell activation
Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
positive regulation of cell activation
Any process that activates or increases the frequency, rate or extent of activation.
positive regulation of T cell activation
Any process that activates or increases the frequency, rate or extent of T cell activation.
regulation of body fluid levels
Any process that modulates the levels of body fluids.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
localization
Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.
cofactor metabolic process
The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
negative regulation of multicellular organismal process
Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
regulation of lymphocyte activation
Any process that modulates the frequency, rate or extent of lymphocyte activation.
positive regulation of lymphocyte activation
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
protein maturation
Any process leading to the attainment of the full functional capacity of a protein.
regulation of wound healing
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
regulation of biological quality
Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
regulation of response to stress
Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
all
NA
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
negative regulation of multicellular organismal process
Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
negative regulation of biological process
Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
cellular nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
cellular hormone metabolic process
The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells.
cellular catabolic process
The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
cellular biosynthetic process
The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
cellular amino acid and derivative metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
organic acid metabolic process
The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
cellular amino acid and derivative metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.
cellular ketone metabolic process
The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
small molecule catabolic process
The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.
small molecule biosynthetic process
The chemical reactions and pathways resulting in the formation of small molecules, any monomeric molecule of small relative molecular mass.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
immune effector process
Any process of the immune system that occurs as part of an immune response.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
regulation of leukocyte activation
Any process that modulates the frequency, rate, or extent of leukocyte activation.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
leukocyte activation
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
positive regulation of cell activation
Any process that activates or increases the frequency, rate or extent of activation.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of cell activation
Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
regulation of coagulation
Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
negative regulation of multicellular organismal process
Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
negative regulation of coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
regulation of response to stress
Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
regulation of response to external stimulus
Any process that modulates the frequency, rate or extent of a response to an external stimulus.
regulation of body fluid levels
Any process that modulates the levels of body fluids.
cellular amine metabolic process
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
organic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.
organic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.
protein maturation
Any process leading to the attainment of the full functional capacity of a protein.
organic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.
organic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.
aromatic compound catabolic process
The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.
oxoacid metabolic process
The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
cellular carbohydrate metabolic process
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
lipid biosynthetic process
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
monosaccharide metabolic process
The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
regulation of immune effector process
Any process that modulates the frequency, rate, or extent of an immune effector process.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
activation of immune response
Any process that initiates an immune response.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
complement activation, alternative pathway
Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
regulation of lymphocyte activation
Any process that modulates the frequency, rate or extent of lymphocyte activation.
positive regulation of lymphocyte activation
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
regulation of leukocyte activation
Any process that modulates the frequency, rate, or extent of leukocyte activation.
positive regulation of cell activation
Any process that activates or increases the frequency, rate or extent of activation.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
negative regulation of blood coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation.
negative regulation of coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.
regulation of blood coagulation
Any process that modulates the frequency, rate or extent of blood coagulation.
blood coagulation
The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
regulation of blood coagulation
Any process that modulates the frequency, rate or extent of blood coagulation.
innate immune response
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
inflammatory response
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
hormone metabolic process
The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.
cellular amino acid metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.
cellular amino acid catabolic process
The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.
aromatic amino acid family metabolic process
The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
cellular biogenic amine metabolic process
The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
aromatic amino acid family catabolic process
The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
steroid biosynthetic process
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
androgen metabolic process
The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
sterol metabolic process
The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
positive regulation of lymphocyte activation
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
B cell mediated immunity
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
complement activation, classical pathway
Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.
regulation of T cell activation
Any process that modulates the frequency, rate or extent of T cell activation.
positive regulation of T cell activation
Any process that activates or increases the frequency, rate or extent of T cell activation.
negative regulation of blood coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation.
regulation of blood coagulation
Any process that modulates the frequency, rate or extent of blood coagulation.
blood coagulation
The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
regulation of wound healing
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
aromatic amino acid family catabolic process
The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
cellular amino acid catabolic process
The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.
bile acid biosynthetic process
The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.
cellular amino acid metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.
carboxylic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
carboxylic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
serine family amino acid catabolic process
The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
bile acid biosynthetic process
The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.
positive regulation of T cell activation
Any process that activates or increases the frequency, rate or extent of T cell activation.
activation of plasma proteins involved in acute inflammatory response
Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.
bile acid metabolic process
The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
humoral immune response mediated by circulating immunoglobulin
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
endoplasmic reticulum
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
membrane attack complex
A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.
extracellular space
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endoplasmic reticulum lumen
The volume enclosed by the membranes of the endoplasmic reticulum.
endoplasmic reticulum membrane
The lipid bilayer surrounding the endoplasmic reticulum.
stored secretory granule
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
endomembrane system
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
pore complex
Any small opening in a membrane that allows the passage of gases and/or liquids.
cytoplasmic membrane-bounded vesicle
A membrane-bounded vesicle found in the cytoplasm of the cell.
integral to endoplasmic reticulum membrane
Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
organelle membrane
The lipid bilayer surrounding an organelle.
platelet alpha granule
A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).
platelet alpha granule lumen
The volume enclosed by the membrane of the platelet alpha granule.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to endoplasmic reticulum membrane
Located in the endoplasmic reticulum membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to organelle membrane
Located in an organelle membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
integral to organelle membrane
Penetrating at least one phospholipid bilayer of an organelle membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cytoplasmic vesicle
A vesicle formed of membrane or protein, found in the cytoplasm of a cell.
membrane-enclosed lumen
The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
vesicle
Any small, fluid-filled, spherical organelle enclosed by membrane or protein.
vesicle lumen
The volume enclosed by the membrane or protein that forms a vesicle.
membrane-bounded vesicle
Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
nuclear membrane-endoplasmic reticulum network
The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
organelle lumen
The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
cytoplasmic vesicle part
Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
cytoplasmic membrane-bounded vesicle lumen
The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.
intracellular organelle lumen
An organelle lumen that is part of an intracellular organelle.
subsynaptic reticulum
An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.
all
NA
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
organelle lumen
The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
organelle membrane
The lipid bilayer surrounding an organelle.
cytoplasmic vesicle
A vesicle formed of membrane or protein, found in the cytoplasm of a cell.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
intrinsic to organelle membrane
Located in an organelle membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intracellular organelle lumen
An organelle lumen that is part of an intracellular organelle.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
organelle membrane
The lipid bilayer surrounding an organelle.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
nuclear membrane-endoplasmic reticulum network
The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
endoplasmic reticulum membrane
The lipid bilayer surrounding the endoplasmic reticulum.
nuclear membrane-endoplasmic reticulum network
The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.
cytoplasmic vesicle part
Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.
cytoplasmic membrane-bounded vesicle
A membrane-bounded vesicle found in the cytoplasm of the cell.
vesicle lumen
The volume enclosed by the membrane or protein that forms a vesicle.
cytoplasmic membrane-bounded vesicle
A membrane-bounded vesicle found in the cytoplasm of the cell.
intrinsic to endoplasmic reticulum membrane
Located in the endoplasmic reticulum membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
endoplasmic reticulum lumen
The volume enclosed by the membranes of the endoplasmic reticulum.
endoplasmic reticulum membrane
The lipid bilayer surrounding the endoplasmic reticulum.
intrinsic to endoplasmic reticulum membrane
Located in the endoplasmic reticulum membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
cytoplasmic membrane-bounded vesicle lumen
The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
endoplasmic reticulum membrane
The lipid bilayer surrounding the endoplasmic reticulum.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endoplasmic reticulum
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
cytoplasmic vesicle
A vesicle formed of membrane or protein, found in the cytoplasm of a cell.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
cytoplasmic vesicle part
Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.
subsynaptic reticulum
An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.
intrinsic to organelle membrane
Located in an organelle membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
membrane attack complex
A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
cytoplasmic membrane-bounded vesicle lumen
The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
integral to endoplasmic reticulum membrane
Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
pore complex
Any small opening in a membrane that allows the passage of gases and/or liquids.
integral to organelle membrane
Penetrating at least one phospholipid bilayer of an organelle membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
membrane attack complex
A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.
platelet alpha granule lumen
The volume enclosed by the membrane of the platelet alpha granule.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
enzyme inhibitor activity
Stops, prevents or reduces the activity of an enzyme.
endopeptidase inhibitor activity
Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
binding
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
metal ion binding
Interacting selectively and non-covalently with any metal ion.
iron ion binding
Interacting selectively and non-covalently with iron (Fe) ions.
folic acid binding
Interacting selectively and non-covalently with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
endopeptidase regulator activity
Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
amino acid binding
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
peptidase inhibitor activity
Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
vitamin binding
Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
pyridoxal phosphate binding
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
enzyme regulator activity
Modulates the activity of an enzyme.
carboxylic acid binding
Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
ion binding
Interacting selectively and non-covalently with ions, charged atoms or groups of atoms.
cation binding
Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge.
amine binding
Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group.
tetrapyrrole binding
Interacting selectively and non-covalently with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.
transition metal ion binding
Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
cofactor binding
Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
coenzyme binding
Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
peptidase regulator activity
Modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
vitamin B6 binding
Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
all
NA
amino acid binding
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
peptidase inhibitor activity
Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
pyridoxal phosphate binding
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
folic acid binding
Interacting selectively and non-covalently with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
endopeptidase inhibitor activity
Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 04610 | 7.865e-08 | 2.432 | 15 | 21 | Complement and coagulation cascades |
| 01100 | 7.577e-05 | 40.88 | 69 | 353 | Metabolic pathways |
| 00260 | 2.159e-04 | 1.505 | 9 | 13 | Glycine, serine and threonine metabolism |
| 02010 | 2.037e-02 | 1.621 | 7 | 14 | ABC transporters |
| 04950 | 3.266e-02 | 0.9264 | 5 | 8 | Maturity onset diabetes of the young |
| 04146 | 4.530e-02 | 3.474 | 10 | 30 | Peroxisome |
A1CFAPOBEC1 complementation factor (ENSG00000148584), score: 0.77 ABCA1ATP-binding cassette, sub-family A (ABC1), member 1 (ENSG00000165029), score: 0.57 ABCA12ATP-binding cassette, sub-family A (ABC1), member 12 (ENSG00000144452), score: 0.55 ABCB11ATP-binding cassette, sub-family B (MDR/TAP), member 11 (ENSG00000073734), score: 0.74 ABCC1ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (ENSG00000103222), score: -0.59 ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ENSG00000023839), score: 0.65 ABCD3ATP-binding cassette, sub-family D (ALD), member 3 (ENSG00000117528), score: 0.53 ABCG5ATP-binding cassette, sub-family G (WHITE), member 5 (ENSG00000138075), score: 0.77 ABHD5abhydrolase domain containing 5 (ENSG00000011198), score: 0.55 ACAD9acyl-CoA dehydrogenase family, member 9 (ENSG00000177646), score: 0.62 ACBD5acyl-CoA binding domain containing 5 (ENSG00000107897), score: 0.58 ACO1aconitase 1, soluble (ENSG00000122729), score: 0.67 ACP2acid phosphatase 2, lysosomal (ENSG00000134575), score: 0.66 ACSL5acyl-CoA synthetase long-chain family member 5 (ENSG00000197142), score: 0.68 ACSM5acyl-CoA synthetase medium-chain family member 5 (ENSG00000183549), score: 0.74 ACSS3acyl-CoA synthetase short-chain family member 3 (ENSG00000111058), score: 0.64 ADRA1Badrenergic, alpha-1B-, receptor (ENSG00000170214), score: 0.54 AFMIDarylformamidase (ENSG00000183077), score: 0.62 AGXTalanine-glyoxylate aminotransferase (ENSG00000172482), score: 0.84 AHRaryl hydrocarbon receptor (ENSG00000106546), score: 0.82 AIFM2apoptosis-inducing factor, mitochondrion-associated, 2 (ENSG00000042286), score: 0.53 AKAP12A kinase (PRKA) anchor protein 12 (ENSG00000131016), score: -0.6 AKR1D1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (ENSG00000122787), score: 0.85 AKT3v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) (ENSG00000117020), score: -0.63 ALAS1aminolevulinate, delta-, synthase 1 (ENSG00000023330), score: 0.57 ALBalbumin (ENSG00000163631), score: 0.84 ALDH2aldehyde dehydrogenase 2 family (mitochondrial) (ENSG00000111275), score: 0.61 ALDH8A1aldehyde dehydrogenase 8 family, member A1 (ENSG00000118514), score: 0.61 ALDH9A1aldehyde dehydrogenase 9 family, member A1 (ENSG00000143149), score: 0.53 AMBPalpha-1-microglobulin/bikunin precursor (ENSG00000106927), score: 0.8 AMDHD1amidohydrolase domain containing 1 (ENSG00000139344), score: 0.81 ANK2ankyrin 2, neuronal (ENSG00000145362), score: -0.7 ANO1anoctamin 1, calcium activated chloride channel (ENSG00000131620), score: 0.71 ANXA10annexin A10 (ENSG00000109511), score: 0.55 AP2B1adaptor-related protein complex 2, beta 1 subunit (ENSG00000006125), score: -0.58 ARCN1archain 1 (ENSG00000095139), score: 0.62 ARHGEF10Rho guanine nucleotide exchange factor (GEF) 10 (ENSG00000104728), score: -0.67 ARL3ADP-ribosylation factor-like 3 (ENSG00000138175), score: -0.57 ARRDC3arrestin domain containing 3 (ENSG00000113369), score: 0.57 ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ENSG00000153317), score: -0.56 ASPGasparaginase homolog (S. cerevisiae) (ENSG00000166183), score: 0.7 ATMINATM interactor (ENSG00000166454), score: -0.63 ATOH8atonal homolog 8 (Drosophila) (ENSG00000168874), score: 0.51 ATP2C1ATPase, Ca++ transporting, type 2C, member 1 (ENSG00000017260), score: -0.57 ATRNattractin (ENSG00000088812), score: 0.6 BBOX1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (ENSG00000129151), score: 0.6 BCHEbutyrylcholinesterase (ENSG00000114200), score: 0.6 BCMO1beta-carotene 15,15'-monooxygenase 1 (ENSG00000135697), score: 0.62 BLMHbleomycin hydrolase (ENSG00000108578), score: 0.54 BPGM2,3-bisphosphoglycerate mutase (ENSG00000172331), score: -0.56 BPTFbromodomain PHD finger transcription factor (ENSG00000171634), score: -0.56 C10orf47chromosome 10 open reading frame 47 (ENSG00000148426), score: 0.52 C12orf66chromosome 12 open reading frame 66 (ENSG00000174206), score: 0.54 C13orf15chromosome 13 open reading frame 15 (ENSG00000102760), score: -0.57 C1orf130chromosome 1 open reading frame 130 (ENSG00000184454), score: 0.57 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.85 C5complement component 5 (ENSG00000106804), score: 0.81 C5orf33chromosome 5 open reading frame 33 (ENSG00000152620), score: 0.67 C8Acomplement component 8, alpha polypeptide (ENSG00000157131), score: 0.92 C8Bcomplement component 8, beta polypeptide (ENSG00000021852), score: 0.65 C8Gcomplement component 8, gamma polypeptide (ENSG00000176919), score: 0.78 C9orf150chromosome 9 open reading frame 150 (ENSG00000153714), score: 0.57 CACNB2calcium channel, voltage-dependent, beta 2 subunit (ENSG00000165995), score: -0.56 CAMSAP1calmodulin regulated spectrin-associated protein 1 (ENSG00000130559), score: -0.68 CAMSAP1L1calmodulin regulated spectrin-associated protein 1-like 1 (ENSG00000118200), score: -0.56 CD28CD28 molecule (ENSG00000178562), score: 0.72 CDC42BPACDC42 binding protein kinase alpha (DMPK-like) (ENSG00000143776), score: -0.67 CDH1cadherin 1, type 1, E-cadherin (epithelial) (ENSG00000039068), score: 0.64 CDK14cyclin-dependent kinase 14 (ENSG00000058091), score: -0.62 CDO1cysteine dioxygenase, type I (ENSG00000129596), score: 0.67 CDR2Lcerebellar degeneration-related protein 2-like (ENSG00000109089), score: -0.61 CEPT1choline/ethanolamine phosphotransferase 1 (ENSG00000134255), score: 0.66 CLDN1claudin 1 (ENSG00000163347), score: 0.84 CLINT1clathrin interactor 1 (ENSG00000113282), score: 0.57 CLN5ceroid-lipofuscinosis, neuronal 5 (ENSG00000102805), score: 0.58 COLEC10collectin sub-family member 10 (C-type lectin) (ENSG00000184374), score: 0.77 COLEC11collectin sub-family member 11 (ENSG00000118004), score: 0.6 COMTD1catechol-O-methyltransferase domain containing 1 (ENSG00000165644), score: 0.6 CPB2carboxypeptidase B2 (plasma) (ENSG00000080618), score: 0.82 CPOXcoproporphyrinogen oxidase (ENSG00000080819), score: 0.56 CRAMP1LCrm, cramped-like (Drosophila) (ENSG00000007545), score: -0.59 CREB3L3cAMP responsive element binding protein 3-like 3 (ENSG00000060566), score: 0.8 CREG1cellular repressor of E1A-stimulated genes 1 (ENSG00000143162), score: 0.56 CRLS1cardiolipin synthase 1 (ENSG00000088766), score: 0.53 CRYABcrystallin, alpha B (ENSG00000109846), score: -0.63 CRYGNcrystallin, gamma N (ENSG00000127377), score: 0.55 CTBSchitobiase, di-N-acetyl- (ENSG00000117151), score: 0.67 CTHcystathionase (cystathionine gamma-lyase) (ENSG00000116761), score: 0.67 CYB5Acytochrome b5 type A (microsomal) (ENSG00000166347), score: 0.57 CYBASC3cytochrome b, ascorbate dependent 3 (ENSG00000162144), score: 0.6 CYBBcytochrome b-245, beta polypeptide (ENSG00000165168), score: 0.56 CYP39A1cytochrome P450, family 39, subfamily A, polypeptide 1 (ENSG00000146233), score: 0.96 CYP7B1cytochrome P450, family 7, subfamily B, polypeptide 1 (ENSG00000172817), score: 0.68 CYTSBcytospin B (ENSG00000128487), score: -0.59 DAKdihydroxyacetone kinase 2 homolog (S. cerevisiae) (ENSG00000149476), score: 0.7 DDOSTdolichyl-diphosphooligosaccharide--protein glycosyltransferase (ENSG00000244038), score: 0.62 DECR22,4-dienoyl CoA reductase 2, peroxisomal (ENSG00000242612), score: 0.66 DENND5ADENN/MADD domain containing 5A (ENSG00000184014), score: -0.59 DERL1Der1-like domain family, member 1 (ENSG00000136986), score: 0.53 DHCR77-dehydrocholesterol reductase (ENSG00000172893), score: 0.52 DHTKD1dehydrogenase E1 and transketolase domain containing 1 (ENSG00000181192), score: 0.71 DMGDHdimethylglycine dehydrogenase (ENSG00000132837), score: 0.56 DNAJC22DnaJ (Hsp40) homolog, subfamily C, member 22 (ENSG00000178401), score: 0.63 DNMBPdynamin binding protein (ENSG00000107554), score: 0.55 DPYSdihydropyrimidinase (ENSG00000147647), score: 0.59 DTNAdystrobrevin, alpha (ENSG00000134769), score: -0.58 ECHDC3enoyl CoA hydratase domain containing 3 (ENSG00000134463), score: 0.54 EDEM1ER degradation enhancer, mannosidase alpha-like 1 (ENSG00000134109), score: 0.72 EGFRepidermal growth factor receptor (ENSG00000146648), score: 0.6 EHHADHenoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (ENSG00000113790), score: 0.63 EIF4EBP1eukaryotic translation initiation factor 4E binding protein 1 (ENSG00000187840), score: 0.62 EPB41L3erythrocyte membrane protein band 4.1-like 3 (ENSG00000082397), score: -0.57 EPHA7EPH receptor A7 (ENSG00000135333), score: -0.6 EPHX1epoxide hydrolase 1, microsomal (xenobiotic) (ENSG00000143819), score: 0.59 EPHX2epoxide hydrolase 2, cytoplasmic (ENSG00000120915), score: 0.53 EPT1ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) (ENSG00000138018), score: 0.54 ERLIN2ER lipid raft associated 2 (ENSG00000147475), score: 0.55 ERN1endoplasmic reticulum to nucleus signaling 1 (ENSG00000178607), score: 0.57 ESR1estrogen receptor 1 (ENSG00000091831), score: 0.79 ESRP2epithelial splicing regulatory protein 2 (ENSG00000103067), score: 0.64 ETNK2ethanolamine kinase 2 (ENSG00000143845), score: 0.54 EXOC1exocyst complex component 1 (ENSG00000090989), score: -0.58 F10coagulation factor X (ENSG00000126218), score: 0.64 F2coagulation factor II (thrombin) (ENSG00000180210), score: 0.81 F2RL2coagulation factor II (thrombin) receptor-like 2 (ENSG00000164220), score: 0.54 F9coagulation factor IX (ENSG00000101981), score: 0.94 FAF2Fas associated factor family member 2 (ENSG00000113194), score: 0.6 FAM164Afamily with sequence similarity 164, member A (ENSG00000104427), score: -0.56 FAM82Bfamily with sequence similarity 82, member B (ENSG00000176623), score: 0.54 FAR1fatty acyl CoA reductase 1 (ENSG00000197601), score: -0.64 FETUBfetuin B (ENSG00000090512), score: 1 FGBfibrinogen beta chain (ENSG00000171564), score: 0.79 FGF1fibroblast growth factor 1 (acidic) (ENSG00000113578), score: -0.62 FGF9fibroblast growth factor 9 (glia-activating factor) (ENSG00000102678), score: -0.57 FGFR4fibroblast growth factor receptor 4 (ENSG00000160867), score: 0.73 FGGfibrinogen gamma chain (ENSG00000171557), score: 0.79 FHOD3formin homology 2 domain containing 3 (ENSG00000134775), score: -0.6 FN1fibronectin 1 (ENSG00000115414), score: 0.76 FPGSfolylpolyglutamate synthase (ENSG00000136877), score: 0.63 FRRS1ferric-chelate reductase 1 (ENSG00000156869), score: 0.52 FSTfollistatin (ENSG00000134363), score: 0.68 FZD5frizzled homolog 5 (Drosophila) (ENSG00000163251), score: 0.81 GALK1galactokinase 1 (ENSG00000108479), score: 0.57 GAMTguanidinoacetate N-methyltransferase (ENSG00000130005), score: 0.54 GBE1glucan (1,4-alpha-), branching enzyme 1 (ENSG00000114480), score: 0.69 GCH1GTP cyclohydrolase 1 (ENSG00000131979), score: 0.65 GDF2growth differentiation factor 2 (ENSG00000128802), score: 0.71 GJB1gap junction protein, beta 1, 32kDa (ENSG00000169562), score: 0.66 GK5glycerol kinase 5 (putative) (ENSG00000175066), score: 0.62 GLDCglycine dehydrogenase (decarboxylating) (ENSG00000178445), score: 0.62 GLT25D1glycosyltransferase 25 domain containing 1 (ENSG00000130309), score: 0.52 GLYCTKglycerate kinase (ENSG00000168237), score: 0.58 GNB5guanine nucleotide binding protein (G protein), beta 5 (ENSG00000069966), score: -0.59 GNEglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (ENSG00000159921), score: 0.66 GNMTglycine N-methyltransferase (ENSG00000124713), score: 0.72 GPAMglycerol-3-phosphate acyltransferase, mitochondrial (ENSG00000119927), score: 0.68 GPLD1glycosylphosphatidylinositol specific phospholipase D1 (ENSG00000112293), score: 0.65 GPR114G protein-coupled receptor 114 (ENSG00000159618), score: 0.6 GPR146G protein-coupled receptor 146 (ENSG00000164849), score: 0.72 GRAMD1BGRAM domain containing 1B (ENSG00000023171), score: -0.57 H6PDhexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) (ENSG00000049239), score: 0.58 HABP2hyaluronan binding protein 2 (ENSG00000148702), score: 0.71 HALhistidine ammonia-lyase (ENSG00000084110), score: 0.88 HAO1hydroxyacid oxidase (glycolate oxidase) 1 (ENSG00000101323), score: 0.8 HDGFRP3hepatoma-derived growth factor, related protein 3 (ENSG00000166503), score: -0.66 HEBP1heme binding protein 1 (ENSG00000013583), score: 0.52 HGDhomogentisate 1,2-dioxygenase (ENSG00000113924), score: 0.64 HGFhepatocyte growth factor (hepapoietin A; scatter factor) (ENSG00000019991), score: 0.52 HM13histocompatibility (minor) 13 (ENSG00000101294), score: 0.63 HNF1AHNF1 homeobox A (ENSG00000135100), score: 0.63 HNF4Ahepatocyte nuclear factor 4, alpha (ENSG00000101076), score: 0.54 HPXhemopexin (ENSG00000110169), score: 0.84 HRGhistidine-rich glycoprotein (ENSG00000113905), score: 0.87 HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (ENSG00000044574), score: 0.56 ICOSLGinducible T-cell co-stimulator ligand (ENSG00000160223), score: 0.54 IDH1isocitrate dehydrogenase 1 (NADP+), soluble (ENSG00000138413), score: 0.62 IDH3Aisocitrate dehydrogenase 3 (NAD+) alpha (ENSG00000166411), score: -0.66 IFT20intraflagellar transport 20 homolog (Chlamydomonas) (ENSG00000109083), score: 0.58 IGF1insulin-like growth factor 1 (somatomedin C) (ENSG00000017427), score: 0.8 IGFBP1insulin-like growth factor binding protein 1 (ENSG00000146678), score: 0.75 IGSF6immunoglobulin superfamily, member 6 (ENSG00000140749), score: 0.64 IHHIndian hedgehog (ENSG00000163501), score: 0.67 IKZF1IKAROS family zinc finger 1 (Ikaros) (ENSG00000185811), score: 0.52 IKZF3IKAROS family zinc finger 3 (Aiolos) (ENSG00000161405), score: 0.74 IL10RAinterleukin 10 receptor, alpha (ENSG00000110324), score: 0.63 IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (ENSG00000113302), score: 0.72 IL1R2interleukin 1 receptor, type II (ENSG00000115590), score: 0.66 IL1RAPinterleukin 1 receptor accessory protein (ENSG00000196083), score: 0.69 IL22RA2interleukin 22 receptor, alpha 2 (ENSG00000164485), score: 0.78 IL28RAinterleukin 28 receptor, alpha (interferon, lambda receptor) (ENSG00000185436), score: 0.72 IL2RBinterleukin 2 receptor, beta (ENSG00000100385), score: 0.61 IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor) (ENSG00000134352), score: 0.7 IL7Rinterleukin 7 receptor (ENSG00000168685), score: 0.6 INHBAinhibin, beta A (ENSG00000122641), score: 0.89 IRF8interferon regulatory factor 8 (ENSG00000140968), score: 0.66 IYDiodotyrosine deiodinase (ENSG00000009765), score: 0.7 JAG2jagged 2 (ENSG00000184916), score: -0.55 JAM3junctional adhesion molecule 3 (ENSG00000166086), score: -0.72 KIDINS220kinase D-interacting substrate, 220kDa (ENSG00000134313), score: -0.65 KIFAP3kinesin-associated protein 3 (ENSG00000075945), score: -0.63 KLBklotho beta (ENSG00000134962), score: 0.81 KLF15Kruppel-like factor 15 (ENSG00000163884), score: 0.54 KLF3Kruppel-like factor 3 (basic) (ENSG00000109787), score: 0.56 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (ENSG00000117009), score: 0.6 LAG3lymphocyte-activation gene 3 (ENSG00000089692), score: 0.56 LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) (ENSG00000043462), score: 0.57 LEAP2liver expressed antimicrobial peptide 2 (ENSG00000164406), score: 0.72 LECT2leukocyte cell-derived chemotaxin 2 (ENSG00000145826), score: 0.74 LEPRE1leucine proline-enriched proteoglycan (leprecan) 1 (ENSG00000117385), score: 0.65 LHX8LIM homeobox 8 (ENSG00000162624), score: 0.55 LIPClipase, hepatic (ENSG00000166035), score: 0.55 LPIN2lipin 2 (ENSG00000101577), score: 0.65 LRATlecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) (ENSG00000121207), score: 0.61 LRRC49leucine rich repeat containing 49 (ENSG00000137821), score: -0.62 LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (ENSG00000160285), score: 0.52 LYSMD3LysM, putative peptidoglycan-binding, domain containing 3 (ENSG00000176018), score: 0.57 MARVELD2MARVEL domain containing 2 (ENSG00000152939), score: 0.52 MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (ENSG00000127241), score: 0.66 MASP2mannan-binding lectin serine peptidase 2 (ENSG00000009724), score: 0.76 MAT1Amethionine adenosyltransferase I, alpha (ENSG00000151224), score: 0.84 MBNL3muscleblind-like 3 (Drosophila) (ENSG00000076770), score: 0.55 MFSD2Amajor facilitator superfamily domain containing 2A (ENSG00000168389), score: 0.57 MGAT4Bmannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B (ENSG00000161013), score: 0.56 MGAT5mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase (ENSG00000152127), score: -0.6 MIA3melanoma inhibitory activity family, member 3 (ENSG00000154305), score: 0.54 MINPP1multiple inositol-polyphosphate phosphatase 1 (ENSG00000107789), score: 0.54 MOCOSmolybdenum cofactor sulfurase (ENSG00000075643), score: 0.67 MPPED2metallophosphoesterase domain containing 2 (ENSG00000066382), score: -0.6 MTMR14myotubularin related protein 14 (ENSG00000163719), score: 0.52 MTMR2myotubularin related protein 2 (ENSG00000087053), score: -0.63 MTTPmicrosomal triglyceride transfer protein (ENSG00000138823), score: 0.79 MUTmethylmalonyl CoA mutase (ENSG00000146085), score: 0.54 MYO1Bmyosin IB (ENSG00000128641), score: 0.66 MYO1Fmyosin IF (ENSG00000142347), score: 0.53 NADKNAD kinase (ENSG00000008130), score: 0.55 NAGAN-acetylgalactosaminidase, alpha- (ENSG00000198951), score: 0.59 NAPRT1nicotinate phosphoribosyltransferase domain containing 1 (ENSG00000147813), score: 0.6 NEBLnebulette (ENSG00000078114), score: -0.56 NFIAnuclear factor I/A (ENSG00000162599), score: 0.63 NIPSNAP1nipsnap homolog 1 (C. elegans) (ENSG00000184117), score: 0.58 NR0B2nuclear receptor subfamily 0, group B, member 2 (ENSG00000131910), score: 0.71 NR1H3nuclear receptor subfamily 1, group H, member 3 (ENSG00000025434), score: 0.59 NR1H4nuclear receptor subfamily 1, group H, member 4 (ENSG00000012504), score: 0.65 NR5A2nuclear receptor subfamily 5, group A, member 2 (ENSG00000116833), score: 0.87 NRBF2nuclear receptor binding factor 2 (ENSG00000148572), score: 0.57 NUDT12nudix (nucleoside diphosphate linked moiety X)-type motif 12 (ENSG00000112874), score: 0.63 OIT3oncoprotein induced transcript 3 (ENSG00000138315), score: 0.73 ONECUT1one cut homeobox 1 (ENSG00000169856), score: 0.79 OSTalphaorganic solute transporter alpha (ENSG00000163959), score: 0.72 OTCornithine carbamoyltransferase (ENSG00000036473), score: 0.66 P2RX4purinergic receptor P2X, ligand-gated ion channel, 4 (ENSG00000135124), score: 0.54 PAHphenylalanine hydroxylase (ENSG00000171759), score: 0.71 PANK1pantothenate kinase 1 (ENSG00000152782), score: 0.56 PAPSS23'-phosphoadenosine 5'-phosphosulfate synthase 2 (ENSG00000198682), score: 0.61 PAQR9progestin and adipoQ receptor family member IX (ENSG00000188582), score: 0.52 PARP16poly (ADP-ribose) polymerase family, member 16 (ENSG00000138617), score: 0.55 PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial) (ENSG00000100889), score: 0.73 PCYOX1prenylcysteine oxidase 1 (ENSG00000116005), score: 0.61 PDCD1LG2programmed cell death 1 ligand 2 (ENSG00000197646), score: 0.65 PDE1Aphosphodiesterase 1A, calmodulin-dependent (ENSG00000115252), score: -0.6 PDE7Aphosphodiesterase 7A (ENSG00000205268), score: -0.7 PDIA3protein disulfide isomerase family A, member 3 (ENSG00000167004), score: 0.63 PDIA5protein disulfide isomerase family A, member 5 (ENSG00000065485), score: 0.63 PDIA6protein disulfide isomerase family A, member 6 (ENSG00000143870), score: 0.52 PDP1pyruvate dehyrogenase phosphatase catalytic subunit 1 (ENSG00000164951), score: -0.61 PDP2pyruvate dehyrogenase phosphatase catalytic subunit 2 (ENSG00000172840), score: 0.77 PEMTphosphatidylethanolamine N-methyltransferase (ENSG00000133027), score: 0.76 PHKA2phosphorylase kinase, alpha 2 (liver) (ENSG00000044446), score: 0.62 PIK3R3phosphoinositide-3-kinase, regulatory subunit 3 (gamma) (ENSG00000117461), score: -0.63 PIP5K1Bphosphatidylinositol-4-phosphate 5-kinase, type I, beta (ENSG00000107242), score: -0.6 PLA2G12Bphospholipase A2, group XIIB (ENSG00000138308), score: 0.74 PLATplasminogen activator, tissue (ENSG00000104368), score: -0.58 PLCB4phospholipase C, beta 4 (ENSG00000101333), score: -0.56 PLCL1phospholipase C-like 1 (ENSG00000115896), score: -0.59 PLXDC2plexin domain containing 2 (ENSG00000120594), score: -0.67 PM20D1peptidase M20 domain containing 1 (ENSG00000162877), score: 0.58 PPAPDC1Bphosphatidic acid phosphatase type 2 domain containing 1B (ENSG00000147535), score: 0.64 PPEF2protein phosphatase, EF-hand calcium binding domain 2 (ENSG00000156194), score: 0.62 PPIBpeptidylprolyl isomerase B (cyclophilin B) (ENSG00000166794), score: 0.58 PRICKLE1prickle homolog 1 (Drosophila) (ENSG00000139174), score: -0.58 PROX1prospero homeobox 1 (ENSG00000117707), score: 0.58 PROZprotein Z, vitamin K-dependent plasma glycoprotein (ENSG00000126231), score: 0.73 PRRG4proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) (ENSG00000135378), score: 0.69 PTBP2polypyrimidine tract binding protein 2 (ENSG00000117569), score: -0.62 PYGLphosphorylase, glycogen, liver (ENSG00000100504), score: 0.73 RAB17RAB17, member RAS oncogene family (ENSG00000124839), score: 0.53 RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (ENSG00000128340), score: 0.58 RANBP10RAN binding protein 10 (ENSG00000141084), score: 0.61 RAPH1Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 (ENSG00000173166), score: 0.56 RASL11BRAS-like, family 11, member B (ENSG00000128045), score: -0.59 RBKSribokinase (ENSG00000171174), score: 0.57 RBP4retinol binding protein 4, plasma (ENSG00000138207), score: 0.67 RCN2reticulocalbin 2, EF-hand calcium binding domain (ENSG00000117906), score: -0.58 RGNregucalcin (senescence marker protein-30) (ENSG00000130988), score: 0.61 RGS18regulator of G-protein signaling 18 (ENSG00000150681), score: 0.8 RNF130ring finger protein 130 (ENSG00000113269), score: 0.51 RNF157ring finger protein 157 (ENSG00000141576), score: -0.61 RNF43ring finger protein 43 (ENSG00000108375), score: 0.54 RRBP1ribosome binding protein 1 homolog 180kDa (dog) (ENSG00000125844), score: 0.61 RXRAretinoid X receptor, alpha (ENSG00000186350), score: 0.52 SARDHsarcosine dehydrogenase (ENSG00000123453), score: 0.67 SASH3SAM and SH3 domain containing 3 (ENSG00000122122), score: 0.6 SCARB1scavenger receptor class B, member 1 (ENSG00000073060), score: 0.71 SCRN1secernin 1 (ENSG00000136193), score: -0.62 SDC2syndecan 2 (ENSG00000169439), score: 0.88 SDF2stromal cell-derived factor 2 (ENSG00000132581), score: 0.58 SEBOXSEBOX homeobox (ENSG00000109072), score: 0.8 SEC16ASEC16 homolog A (S. cerevisiae) (ENSG00000148396), score: 0.53 SEC16BSEC16 homolog B (S. cerevisiae) (ENSG00000120341), score: 0.75 SEC23ASec23 homolog A (S. cerevisiae) (ENSG00000100934), score: 0.53 SEC24DSEC24 family, member D (S. cerevisiae) (ENSG00000150961), score: 0.58 SEC61A1Sec61 alpha 1 subunit (S. cerevisiae) (ENSG00000058262), score: 0.63 SEPSECSSep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase (ENSG00000109618), score: 0.53 SERPINA10serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 (ENSG00000140093), score: 0.72 SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 1 (ENSG00000117601), score: 0.83 SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (ENSG00000135919), score: -0.66 SERPINF2serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (ENSG00000167711), score: 0.65 SFXN2sideroflexin 2 (ENSG00000156398), score: 0.52 SGPL1sphingosine-1-phosphate lyase 1 (ENSG00000166224), score: 0.72 SH3BP5SH3-domain binding protein 5 (BTK-associated) (ENSG00000131370), score: -0.56 SIK2salt-inducible kinase 2 (ENSG00000170145), score: 0.53 SIKE1suppressor of IKBKE 1 (ENSG00000052723), score: 0.58 SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (ENSG00000018280), score: 0.57 SLC16A10solute carrier family 16, member 10 (aromatic amino acid transporter) (ENSG00000112394), score: 0.69 SLC16A2solute carrier family 16, member 2 (monocarboxylic acid transporter 8) (ENSG00000147100), score: 0.64 SLC17A9solute carrier family 17, member 9 (ENSG00000101194), score: 0.59 SLC19A2solute carrier family 19 (thiamine transporter), member 2 (ENSG00000117479), score: 0.59 SLC25A47solute carrier family 25, member 47 (ENSG00000140107), score: 0.7 SLC26A5solute carrier family 26, member 5 (prestin) (ENSG00000170615), score: 0.57 SLC2A10solute carrier family 2 (facilitated glucose transporter), member 10 (ENSG00000197496), score: 0.83 SLC2A2solute carrier family 2 (facilitated glucose transporter), member 2 (ENSG00000163581), score: 0.76 SLC2A9solute carrier family 2 (facilitated glucose transporter), member 9 (ENSG00000109667), score: 0.73 SLC30A1solute carrier family 30 (zinc transporter), member 1 (ENSG00000170385), score: 0.63 SLC30A10solute carrier family 30, member 10 (ENSG00000196660), score: 0.66 SLC30A7solute carrier family 30 (zinc transporter), member 7 (ENSG00000162695), score: 0.59 SLC31A1solute carrier family 31 (copper transporters), member 1 (ENSG00000136868), score: 0.54 SLC33A1solute carrier family 33 (acetyl-CoA transporter), member 1 (ENSG00000169359), score: 0.68 SLC35C1solute carrier family 35, member C1 (ENSG00000181830), score: 0.58 SLC35D1solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 (ENSG00000116704), score: 0.73 SLC38A4solute carrier family 38, member 4 (ENSG00000139209), score: 0.89 SLC39A8solute carrier family 39 (zinc transporter), member 8 (ENSG00000138821), score: 0.66 SLC39A9solute carrier family 39 (zinc transporter), member 9 (ENSG00000029364), score: 0.52 SLC40A1solute carrier family 40 (iron-regulated transporter), member 1 (ENSG00000138449), score: 0.54 SLC41A2solute carrier family 41, member 2 (ENSG00000136052), score: 0.57 SLC46A1solute carrier family 46 (folate transporter), member 1 (ENSG00000076351), score: 0.76 SLC7A2solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 (ENSG00000003989), score: 0.74 SLIT3slit homolog 3 (Drosophila) (ENSG00000184347), score: -0.65 SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 (ENSG00000082014), score: -0.62 SPI1spleen focus forming virus (SFFV) proviral integration oncogene spi1 (ENSG00000066336), score: 0.64 SPINK4serine peptidase inhibitor, Kazal type 4 (ENSG00000122711), score: 0.6 SPIRE1spire homolog 1 (Drosophila) (ENSG00000134278), score: -0.66 SPP2secreted phosphoprotein 2, 24kDa (ENSG00000072080), score: 0.94 SRD5A2steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (ENSG00000049319), score: 0.62 SSR1signal sequence receptor, alpha (ENSG00000124783), score: 0.52 ST6GAL1ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 (ENSG00000073849), score: 0.75 STAB1stabilin 1 (ENSG00000010327), score: 0.52 STAB2stabilin 2 (ENSG00000136011), score: 0.75 STARD5StAR-related lipid transfer (START) domain containing 5 (ENSG00000172345), score: 0.65 STT3BSTT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) (ENSG00000163527), score: 0.54 TATtyrosine aminotransferase (ENSG00000198650), score: 0.87 TBC1D8BTBC1 domain family, member 8B (with GRAM domain) (ENSG00000133138), score: 0.61 TBX3T-box 3 (ENSG00000135111), score: 0.71 TDO2tryptophan 2,3-dioxygenase (ENSG00000151790), score: 0.84 TEX264testis expressed 264 (ENSG00000164081), score: 0.6 TGFBItransforming growth factor, beta-induced, 68kDa (ENSG00000120708), score: 0.62 TM4SF4transmembrane 4 L six family member 4 (ENSG00000169903), score: 0.69 TMCO7transmembrane and coiled-coil domains 7 (ENSG00000103047), score: 0.6 TMED5transmembrane emp24 protein transport domain containing 5 (ENSG00000117500), score: 0.67 TMEM195transmembrane protein 195 (ENSG00000187546), score: 0.66 TMEM41Atransmembrane protein 41A (ENSG00000163900), score: 0.54 TMEM82transmembrane protein 82 (ENSG00000162460), score: 0.64 TNFSF10tumor necrosis factor (ligand) superfamily, member 10 (ENSG00000121858), score: 0.58 TOB1transducer of ERBB2, 1 (ENSG00000141232), score: 0.55 TOMM40Ltranslocase of outer mitochondrial membrane 40 homolog (yeast)-like (ENSG00000158882), score: 0.55 TOR1Atorsin family 1, member A (torsin A) (ENSG00000136827), score: 0.52 TP53BP1tumor protein p53 binding protein 1 (ENSG00000067369), score: -0.61 TRAF2TNF receptor-associated factor 2 (ENSG00000127191), score: 0.69 TRAT1T cell receptor associated transmembrane adaptor 1 (ENSG00000163519), score: 0.7 TRPC1transient receptor potential cation channel, subfamily C, member 1 (ENSG00000144935), score: -0.58 TRPM1transient receptor potential cation channel, subfamily M, member 1 (ENSG00000134160), score: 0.53 TSKUtsukushi small leucine rich proteoglycan homolog (Xenopus laevis) (ENSG00000182704), score: 0.68 TTC36tetratricopeptide repeat domain 36 (ENSG00000172425), score: 0.63 TTPAtocopherol (alpha) transfer protein (ENSG00000137561), score: 0.83 TWSG1twisted gastrulation homolog 1 (Drosophila) (ENSG00000128791), score: -0.61 TXNDC12thioredoxin domain containing 12 (endoplasmic reticulum) (ENSG00000117862), score: 0.6 UCK1uridine-cytidine kinase 1 (ENSG00000130717), score: 0.52 UPB1ureidopropionase, beta (ENSG00000100024), score: 0.57 VSIG4V-set and immunoglobulin domain containing 4 (ENSG00000155659), score: 0.76 WDFY2WD repeat and FYVE domain containing 2 (ENSG00000139668), score: 0.8 XCR1chemokine (C motif) receptor 1 (ENSG00000173578), score: 0.94 ZCCHC11zinc finger, CCHC domain containing 11 (ENSG00000134744), score: 0.59
| Id | species | tissue | sex | individual |
|---|---|---|---|---|
| hsa_lv_m1_ca1 | hsa | lv | m | 1 |
| gga_lv_f_ca1 | gga | lv | f | _ |
| mdo_lv_f_ca1 | mdo | lv | f | _ |
| mml_lv_f_ca1 | mml | lv | f | _ |
| mdo_lv_m_ca1 | mdo | lv | m | _ |
| gga_lv_m_ca1 | gga | lv | m | _ |
| mml_lv_m_ca1 | mml | lv | m | _ |
