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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

organic acid transport

The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of, within or between cells by means of some external agent such as a transporter or pore.

vitamin transport

The directed movement of vitamins into, out of, within or between cells by means of some external agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.

carboxylic acid metabolic process

The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

small molecule metabolic process

The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass.

carboxylic acid transport

The directed movement of carboxylic acids into, out of, within or between cells by means of some external agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

all

NA

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

sodium channel complex

An ion channel complex through which sodium ions pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

metal ion transmembrane transporter activity

Catalysis of the transfer of metal ions from one side of a membrane to the other.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

organic acid transmembrane transporter activity

Catalysis of the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

monocarboxylic acid transmembrane transporter activity

Catalysis of the transfer of monocarboxylic acids from one side of the membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

monovalent inorganic cation transmembrane transporter activity

Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

sodium ion transmembrane transporter activity

Catalysis of the transfer of sodium ions (Na+) from one side of a membrane to the other.

symporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

vitamin binding

Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

carboxylic acid transmembrane transporter activity

Catalysis of the transfer of carboxylic acids from one side of the membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

sodium ion transmembrane transporter activity

Catalysis of the transfer of sodium ions (Na+) from one side of a membrane to the other.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0007588	1.665e-06	1.489	12 AQP3, ATP6V0A4, AVPR1A, CLCN5, CLDN16, DAB2, KCNJ1, KCNK5, NPHS2, SCNN1A, SCNN1B, SCNN1G	24	excretion
GO:0006811	4.134e-06	20.59	48 ABCC4, AQP11, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, BSPRY, CLCN5, CLDN16, CLIC3, CLIC6, EGF, GABRP, KCND3, KCNJ1, KCNJ16, KCNK5, LPAR3, PKD2, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC17A5, SLC1A1, SLC22A4, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC39A9, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC9A3, TCN2, TRPM6, TRPM7, TRPV4, WNK1, ZDHHC13	332	ion transport
GO:0006812	1.017e-05	14.14	37 ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, BSPRY, EGF, KCND3, KCNJ1, KCNJ16, KCNK5, LPAR3, PKD2, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC39A9, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC9A3, TCN2, TRPM6, TRPM7, TRPV4	228	cation transport
GO:0051234	1.671e-05	67.18	106 ABCC2, ABCC4, ABCD3, AKAP6, AP1G1, AP1S3, AQP11, AQP3, ARFIP1, ARSB, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, AVPR1A, BSPRY, CLCN5, CLDN16, CLIC3, CLIC6, CLU, CRY2, CSE1L, CUBN, CYB5R4, CYTH1, DAB2, DPP4, EGF, EXOC3, EXOC6, FAM3D, FLVCR1, GABRP, HNF1A, KCND3, KCNJ1, KCNJ16, KCNK5, LLGL2, LPAR3, M6PR, MYO6, NECAB3, NPHS2, OPTN, OSBPL3, OSBPL6, OSTalpha, PKD2, PRLR, RAB19, RAB3IP, RHAG, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SCRN1, SEC22C, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC25A16, SLC25A17, SLC25A48, SLC27A1, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC37A3, SLC39A9, SLC3A1, SLC46A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, SNX2, TCN2, TRPM6, TRPM7, TRPV4, UPK3A, VPS39, VPS54, WNK1, WNT5A, ZDHHC13	1083	establishment of localization
GO:0006810	1.827e-05	66.44	105 ABCC2, ABCC4, ABCD3, AKAP6, AP1G1, AP1S3, AQP11, AQP3, ARFIP1, ARSB, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, AVPR1A, BSPRY, CLCN5, CLDN16, CLIC3, CLIC6, CLU, CRY2, CSE1L, CUBN, CYB5R4, CYTH1, DAB2, EGF, EXOC3, EXOC6, FAM3D, FLVCR1, GABRP, HNF1A, KCND3, KCNJ1, KCNJ16, KCNK5, LLGL2, LPAR3, M6PR, MYO6, NECAB3, NPHS2, OPTN, OSBPL3, OSBPL6, OSTalpha, PKD2, PRLR, RAB19, RAB3IP, RHAG, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SCRN1, SEC22C, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC25A16, SLC25A17, SLC25A48, SLC27A1, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC37A3, SLC39A9, SLC3A1, SLC46A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, SNX2, TCN2, TRPM6, TRPM7, TRPV4, UPK3A, VPS39, VPS54, WNK1, WNT5A, ZDHHC13	1071	transport
GO:0006814	1.959e-05	2.916	15 ATP1B1, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC9A3	47	sodium ion transport
GO:0055085	5.838e-05	17.25	40 ABCC2, ABCC4, ABCD3, AQP3, ATP6V0A4, ATP6V0D2, ATP7A, CLCN5, CRY2, EGF, FLVCR1, KCND3, PKD2, RHAG, RHCG, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC22A4, SLC25A10, SLC25A16, SLC25A17, SLC25A48, SLC30A6, SLC30A7, SLC37A3, SLC39A9, SLC46A1, SLC5A11, SLC5A12, SLC5A9, SLC7A9, SLC9A3, TRPM6, TRPM7, TRPV4	278	transmembrane transport
GO:0030001	7.946e-05	12.34	32 ATP1B1, ATP7A, BSPRY, EGF, KCND3, KCNJ1, KCNJ16, KCNK5, LPAR3, PKD2, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC39A9, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC9A3, TCN2, TRPM6, TRPM7, TRPV4	199	metal ion transport
GO:0015849	1.187e-04	4.28	17 ABCD3, HNF1A, SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC27A1, SLC3A1, SLC46A1, SLC6A19, SLC6A6, SLC7A9	69	organic acid transport
GO:0046942	1.187e-04	4.28	17 ABCD3, HNF1A, SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC27A1, SLC3A1, SLC46A1, SLC6A19, SLC6A6, SLC7A9	69	carboxylic acid transport
GO:0051179	1.671e-04	77.79	114 ABCC2, ABCC4, ABCD3, AKAP6, AP1G1, AP1S3, AQP11, AQP3, ARFIP1, ARSB, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, AVPR1A, BSPRY, CLCN5, CLDN16, CLIC3, CLIC6, CLU, CRY2, CSE1L, CUBN, CYB5R4, CYTH1, DAB2, DPP4, EGF, ENPEP, EXOC3, EXOC6, F2RL1, FAM3D, FERMT1, FLVCR1, GABRP, HNF1A, KCND3, KCNJ1, KCNJ16, KCNK5, LLGL2, LPAR3, M6PR, MAP3K1, MPP1, MYO6, NECAB3, NPHS2, OPTN, OSBPL3, OSBPL6, OSTalpha, PKD2, PLAU, PRLR, RAB19, RAB3IP, REEP1, RHAG, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SCRN1, SEC22C, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC25A16, SLC25A17, SLC25A48, SLC27A1, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC37A3, SLC39A9, SLC3A1, SLC46A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, SNX2, TCN2, TRPM6, TRPM7, TRPV4, UPK3A, VASH1, VPS39, VPS54, WNK1, WNT5A, ZDHHC13	1254	localization
GO:0015672	5.184e-04	6.948	21 ATP1B1, ATP6V0A4, ATP6V0D2, KCND3, KCNJ1, KCNJ16, KCNK5, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC9A3	112	monovalent inorganic cation transport
GO:0046903	1.661e-03	11.91	28 AQP3, ARFIP1, ATP6V0A4, AVPR1A, CLCN5, CLDN16, CYB5R4, DAB2, EGF, EXOC3, EXOC6, FAM3D, HNF1A, KCNJ1, KCNK5, LLGL2, MYO6, NECAB3, NPHS2, PRLR, SCIN, SCNN1A, SCNN1B, SCNN1G, SCRN1, SLC22A4, TRPV4, WNT5A	192	secretion
GO:0051180	3.967e-03	0.4963	5 CUBN, SLC19A1, SLC22A4, SLC46A1, TCN2	8	vitamin transport
GO:0006082	9.744e-03	14.14	29 ACMSD, ACO1, ADIPOR1, AKR1A1, AKR1D1, ALDH6A1, ALDH8A1, ALDH9A1, ASPA, ATP7A, AVPR1A, CCBL1, CTH, DAO, GCLM, HNF1A, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, PCK1, SLC22A4, SLC25A10, SLC27A1, SLC3A1, SLC6A6, SLC7A9	228	organic acid metabolic process
GO:0019752	9.744e-03	14.14	29 ACMSD, ACO1, ADIPOR1, AKR1A1, AKR1D1, ALDH6A1, ALDH8A1, ALDH9A1, ASPA, ATP7A, AVPR1A, CCBL1, CTH, DAO, GCLM, HNF1A, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, PCK1, SLC22A4, SLC25A10, SLC27A1, SLC3A1, SLC6A6, SLC7A9	228	carboxylic acid metabolic process
GO:0043436	9.744e-03	14.14	29 ACMSD, ACO1, ADIPOR1, AKR1A1, AKR1D1, ALDH6A1, ALDH8A1, ALDH9A1, ASPA, ATP7A, AVPR1A, CCBL1, CTH, DAO, GCLM, HNF1A, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, PCK1, SLC22A4, SLC25A10, SLC27A1, SLC3A1, SLC6A6, SLC7A9	228	oxoacid metabolic process
GO:0006519	1.057e-02	8.188	20 ALDH6A1, ALDH9A1, ASPA, ATP7A, BPHL, CCBL1, CTH, DAO, GCLM, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, SLC22A4, SLC27A1, SLC3A1, SLC6A6, SLC7A9	132	cellular amino acid and derivative metabolic process
GO:0044106	1.264e-02	7.072	18 ALDH6A1, ALDH9A1, ASPA, ATP7A, CCBL1, CTH, DAO, GCLM, HNF4A, IVD, KMO, MCCC1, MSRA, SLC22A4, SLC27A1, SLC3A1, SLC6A6, SLC7A9	114	cellular amine metabolic process
GO:0042180	1.311e-02	14.45	29 ACMSD, ACO1, ADIPOR1, AKR1A1, AKR1D1, ALDH6A1, ALDH8A1, ALDH9A1, ASPA, ATP7A, AVPR1A, CCBL1, CTH, DAO, GCLM, HNF1A, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, PCK1, SLC22A4, SLC25A10, SLC27A1, SLC3A1, SLC6A6, SLC7A9	233	cellular ketone metabolic process
GO:0006551	1.524e-02	0.1861	3 DAO, IVD, MCCC1	3	leucine metabolic process
GO:0006520	2.067e-02	5.583	15 ALDH6A1, ASPA, ATP7A, CCBL1, CTH, DAO, GCLM, HNF4A, IVD, KMO, MCCC1, MSRA, SLC3A1, SLC6A6, SLC7A9	90	cellular amino acid metabolic process
GO:0015718	3.679e-02	1.613	7 ABCD3, HNF1A, SLC10A2, SLC16A2, SLC16A4, SLC17A5, SLC27A1	26	monocarboxylic acid transport
GO:0009081	3.871e-02	0.4963	4 ALDH6A1, DAO, IVD, MCCC1	8	branched chain family amino acid metabolic process
GO:0015840	4.100e-02	0.2481	3 AQP11, AQP3, UPK3A	4	urea transport
GO:0042886	4.100e-02	0.2481	3 AQP11, AQP3, UPK3A	4	amide transport
GO:0006081	4.764e-02	0.8685	5 AKR1A1, ALDH8A1, ALDH9A1, DAO, IDH1	14	cellular aldehyde metabolic process
GO:0006767	4.764e-02	0.8685	5 AKR1A1, ALDH9A1, KMO, MCCC1, SLC22A4	14	water-soluble vitamin metabolic process
GO:0046849	4.764e-02	0.8685	5 HNF1A, NOX4, SLC34A1, SPP1, TPP1	14	bone remodeling

Id	Pvalue	ExpCount	Count	Size	Term
GO:0045177	2.155e-10	4.639	25 ABCC2, AKR1A1, ATP1B1, ATP6V0A4, ATP6V0D2, CLCN5, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ITGA8, LGMN, MPDZ, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC22A4, SLC46A1, SLC5A12, SLC9A3, TRPM6, UPK3A	75	apical part of cell
GO:0016324	3.858e-10	3.649	22 ABCC2, AKR1A1, ATP1B1, ATP6V0A4, ATP6V0D2, CUBN, DPEP1, DPP4, ENPEP, EPCAM, MPDZ, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC22A4, SLC46A1, SLC5A12, SLC9A3, TRPM6, UPK3A	59	apical plasma membrane
GO:0044459	4.100e-05	44.59	76 ABCC2, AKR1A1, AQP3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, AVPR1A, BCL10, CASR, CD82, CLCN5, CLDN16, CLDN19, CUBN, DPEP1, DPP4, ENPEP, EPCAM, F2RL1, FERMT1, FLVCR1, FMN1, FZD4, GABRP, ITGA8, ITGB6, ITGB8, KCND3, KCNJ1, KCNJ16, KCNK5, KL, LPAR3, M6PR, MEP1A, MEP1B, MPDZ, MPP1, MYO6, NOX4, NPHS2, RASA3, RHAG, RHCG, SAMD4A, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC19A1, SLC1A1, SLC22A4, SLC25A17, SLC27A1, SLC31A1, SLC34A1, SLC3A1, SLC46A1, SLC4A4, SLC5A12, SLC6A19, SLC6A6, SLC7A9, SLC9A3, ST14, TMPRSS2, TRPM6, TRPV4, TSHR, UPK3A, VEZT	721	plasma membrane part
GO:0005886	1.551e-04	70.08	104 ABCC2, ABCC4, ADIPOR1, AKR1A1, ANKS4B, AQP11, AQP3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, AVPR1A, BCL10, CASR, CD82, CDCP1, CLCN5, CLDN16, CLDN19, CLIC6, CLSTN3, CNTN4, CUBN, CYTH1, DPEP1, DPP4, EGF, ENPEP, EPCAM, F2RL1, FERMT1, FLVCR1, FMN1, FRAS1, FZD4, GABRP, GPR160, ILDR1, IQGAP1, ITCH, ITGA8, ITGB6, ITGB8, IYD, KCND3, KCNJ1, KCNJ16, KCNK5, KL, LGR4, LPAR3, LYPD2, M6PR, MEP1A, MEP1B, MPDZ, MPP1, MYO6, NOX4, NPHS2, OSTalpha, PKD2, PLAU, RAB19, RASA3, RHAG, RHCG, SAMD4A, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC19A1, SLC1A1, SLC22A4, SLC25A17, SLC27A1, SLC31A1, SLC34A1, SLC3A1, SLC41A3, SLC46A1, SLC4A4, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, ST14, TMPRSS2, TRPM6, TRPM7, TRPV4, TSHR, UPK3A, VEZT	1133	plasma membrane
GO:0031224	2.624e-04	100	136 A4GNT, ABCC2, ABCC4, ABCD3, ADIPOR1, AKAP6, ANKLE2, AQP11, AQP3, ATP13A3, ATP1B1, ATP6V0A4, ATP7A, AVPR1A, BCL10, CA12, CASR, CD82, CDCP1, CLCN5, CLDN16, CLDN19, CLIC3, CLIC6, CLSTN3, CNTN4, DPEP1, DPP4, DRAM2, EGF, ENPEP, ENTPD6, EPCAM, ERLIN1, EVC, F2RL1, FLVCR1, FRAS1, FZD4, GABRP, GALNT11, GALNT14, GALNTL1, GPR160, ILDR1, INPP5B, ITGA8, ITGB6, ITGB8, IYD, KCND3, KCNJ1, KCNJ16, KCNK5, KL, KLHDC7A, KMO, LGR4, LPAR3, LYPD2, M6PR, MARVELD3, MEP1A, MEP1B, MPP1, NOX4, NPHS2, OSTalpha, P4HTM, PAQR5, PAQR9, PEX11A, PKD2, PLXDC2, PRLR, RASA3, REEP1, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SEC22C, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC25A16, SLC25A17, SLC25A48, SLC27A1, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC37A3, SLC39A9, SLC3A1, SLC41A3, SLC46A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, SPTLC2, ST14, SUSD2, SUSD3, TMEM106B, TMEM135, TMEM171, TMEM27, TMIGD1, TMPRSS2, TRPM6, TRPM7, TRPV4, TSHR, UPK3A, VEZT, WRB, ZDHHC13, ZMPSTE24, ZPLD1	1617	intrinsic to membrane
GO:0016021	6.032e-04	97.97	132 A4GNT, ABCC2, ABCC4, ABCD3, ADIPOR1, AKAP6, ANKLE2, AQP11, AQP3, ATP13A3, ATP1B1, ATP6V0A4, ATP7A, AVPR1A, BCL10, CA12, CASR, CD82, CDCP1, CLCN5, CLDN16, CLDN19, CLIC3, CLIC6, CLSTN3, DPP4, DRAM2, EGF, ENPEP, ENTPD6, EPCAM, ERLIN1, EVC, F2RL1, FLVCR1, FRAS1, FZD4, GABRP, GALNT11, GALNT14, GALNTL1, GPR160, ILDR1, INPP5B, ITGA8, ITGB6, ITGB8, IYD, KCND3, KCNJ1, KCNJ16, KCNK5, KL, KLHDC7A, KMO, LGR4, LPAR3, M6PR, MARVELD3, MEP1A, MEP1B, MPP1, NOX4, NPHS2, OSTalpha, P4HTM, PAQR5, PAQR9, PEX11A, PKD2, PLXDC2, PRLR, REEP1, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SEC22C, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC25A16, SLC25A17, SLC25A48, SLC27A1, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC37A3, SLC39A9, SLC3A1, SLC41A3, SLC46A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, SPTLC2, ST14, SUSD2, SUSD3, TMEM106B, TMEM135, TMEM171, TMEM27, TMIGD1, TMPRSS2, TRPM6, TRPM7, TRPV4, TSHR, UPK3A, VEZT, WRB, ZDHHC13, ZMPSTE24, ZPLD1	1584	integral to membrane
GO:0005903	1.770e-03	1.113	7 ATP6V0A4, CUBN, ENPEP, SLC13A1, SLC34A1, SLC9A3, TRPM6	18	brush border
GO:0044425	1.802e-03	117.5	150 A4GNT, ABCC2, ABCC4, ABCD3, ADIPOR1, AKAP6, AKR1A1, ANKLE2, AP1G1, AP1S3, AQP11, AQP3, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, AVPR1A, BCL10, CA12, CASR, CD82, CDCP1, CLCN5, CLDN16, CLDN19, CLIC3, CLIC6, CLSTN3, CNTN4, CUBN, DAB2, DPEP1, DPP4, DRAM2, EGF, ENPEP, ENTPD6, EPCAM, ERLIN1, EVC, F2RL1, FERMT1, FLVCR1, FMN1, FRAS1, FZD4, GABRP, GALNT11, GALNT14, GALNTL1, GPR160, ILDR1, INPP5B, ITGA8, ITGB6, ITGB8, IYD, KCND3, KCNJ1, KCNJ16, KCNK5, KL, KLHDC7A, KMO, LGR4, LPAR3, LYPD2, M6PR, MARVELD3, MEP1A, MEP1B, MPDZ, MPP1, MYLIP, MYO6, NECAB3, NOX4, NPHS2, OSTalpha, P4HTM, PAQR5, PAQR9, PEX11A, PKD2, PLXDC2, PRLR, RASA3, REEP1, RHAG, RHCG, SAMD4A, SCNN1A, SCNN1B, SCNN1G, SEC22C, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC25A16, SLC25A17, SLC25A48, SLC27A1, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC37A3, SLC39A9, SLC3A1, SLC41A3, SLC46A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, SPTLC2, ST14, SUSD2, SUSD3, TMEM106B, TMEM135, TMEM171, TMEM27, TMIGD1, TMPRSS2, TRPM6, TRPM7, TRPV4, TSHR, UPK3A, VEZT, VPS39, WRB, ZDHHC13, ZMPSTE24, ZPLD1	1899	membrane part
GO:0031226	2.320e-03	26.16	46 ABCC2, ATP1B1, AVPR1A, CASR, CD82, CLCN5, ENPEP, F2RL1, FLVCR1, FZD4, ITGA8, ITGB6, ITGB8, KCND3, KCNJ1, KCNJ16, KCNK5, KL, LPAR3, M6PR, MEP1A, MEP1B, MPP1, NPHS2, RASA3, RHAG, RHCG, SCNN1G, SLC10A2, SLC16A2, SLC16A4, SLC17A5, SLC19A1, SLC1A1, SLC22A4, SLC25A17, SLC31A1, SLC34A1, SLC3A1, SLC4A4, SLC6A19, SLC6A6, SLC7A9, ST14, TMPRSS2, TSHR	423	intrinsic to plasma membrane
GO:0005887	2.594e-03	25.54	45 ABCC2, ATP1B1, AVPR1A, CASR, CD82, CLCN5, ENPEP, F2RL1, FLVCR1, FZD4, ITGA8, ITGB6, ITGB8, KCND3, KCNJ1, KCNJ16, KCNK5, KL, LPAR3, M6PR, MEP1A, MEP1B, MPP1, NPHS2, RHAG, RHCG, SCNN1G, SLC10A2, SLC16A2, SLC16A4, SLC17A5, SLC19A1, SLC1A1, SLC22A4, SLC25A17, SLC31A1, SLC34A1, SLC3A1, SLC4A4, SLC6A19, SLC6A6, SLC7A9, ST14, TMPRSS2, TSHR	413	integral to plasma membrane
GO:0031253	5.337e-03	2.66	10 ATP6V0A4, CUBN, DPEP1, DPP4, FERMT1, ITGA8, MYO6, SLC34A1, SLC9A3, TRPM6	43	cell projection membrane
GO:0034706	5.691e-03	0.1856	3 SCNN1A, SCNN1B, SCNN1G	3	sodium channel complex
GO:0005773	9.488e-03	5.69	15 ARSB, ASAH1, ATP6V0A4, ATP6V0D2, BCL10, CUBN, DRAM2, GLB1, LGMN, M6PR, NAGA, SLC17A5, SLC3A1, TPP1, VPS39	92	vacuole
GO:0031526	1.440e-02	0.8041	5 ATP6V0A4, CUBN, SLC34A1, SLC9A3, TRPM6	13	brush border membrane
GO:0005604	1.612e-02	2.103	8 COL4A3, COL4A4, EGFL6, LAD1, LAMC2, LAMC3, TIMP3, TINAG	34	basement membrane
GO:0016020	2.114e-02	143.9	170 A4GNT, ABCC2, ABCC4, ABCD3, ADIPOR1, AKAP6, AKR1A1, ANKLE2, ANKS4B, AP1G1, AP1S3, AQP11, AQP3, ARFIP1, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, AVPR1A, BCL10, BSPRY, CA12, CASR, CD82, CDCP1, CLCN5, CLDN16, CLDN19, CLIC3, CLIC6, CLSTN3, CNTN4, CUBN, CYTH1, DAB2, DPEP1, DPP4, DRAM2, EDEM3, EGF, EGFL6, ENPEP, ENTPD6, EPCAM, ERLIN1, EVC, F2RL1, FERMT1, FLVCR1, FMN1, FRAS1, FZD4, GABRP, GALNT11, GALNT14, GALNTL1, GPR160, ILDR1, INPP5B, IQGAP1, ITCH, ITGA8, ITGB6, ITGB8, IVD, IYD, KCND3, KCNJ1, KCNJ16, KCNK5, KL, KLHDC7A, KMO, LAMC3, LDHD, LGR4, LPAR3, LYPD2, M6PR, MARVELD3, MCCC1, MEP1A, MEP1B, MPDZ, MPP1, MYLIP, MYO6, NECAB3, NOX4, NPHS2, NPNT, OSTalpha, P4HTM, PAQR5, PAQR9, PEX11A, PHLDB2, PKD2, PLAU, PLXDC2, PRLR, RAB19, RASA3, REEP1, RHAG, RHCG, SAMD4A, SCNN1A, SCNN1B, SCNN1G, SCRN1, SEC22C, SGK1, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC25A16, SLC25A17, SLC25A48, SLC27A1, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC37A3, SLC39A9, SLC3A1, SLC41A3, SLC46A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, SPTLC2, ST14, SUSD2, SUSD3, TBC1D8, TFCP2L1, TMEM106B, TMEM135, TMEM171, TMEM27, TMIGD1, TMPRSS2, TRPM6, TRPM7, TRPV4, TSHR, UPK3A, VEZT, VPS39, WRB, ZDHHC13, ZMPSTE24, ZPLD1	2327	membrane
GO:0005624	2.308e-02	16.95	30 A4GNT, ABCC2, ABCC4, CUBN, DPP4, ENTPD6, HSD11B2, ITCH, KL, MAP3K1, MEP1A, MEP1B, MPDZ, MPP1, SAMD4A, SCNN1A, SCNN1B, SCNN1G, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC27A1, SLC3A1, WNK1, WNT5A, ZMPSTE24	274	membrane fraction
GO:0000323	3.348e-02	4.701	12 ARSB, ASAH1, BCL10, CUBN, DRAM2, GLB1, LGMN, M6PR, NAGA, SLC17A5, TPP1, VPS39	76	lytic vacuole
GO:0005764	3.348e-02	4.701	12 ARSB, ASAH1, BCL10, CUBN, DRAM2, GLB1, LGMN, M6PR, NAGA, SLC17A5, TPP1, VPS39	76	lysosome
GO:0005626	3.589e-02	17.57	30 A4GNT, ABCC2, ABCC4, CUBN, DPP4, ENTPD6, HSD11B2, ITCH, KL, MAP3K1, MEP1A, MEP1B, MPDZ, MPP1, SAMD4A, SCNN1A, SCNN1B, SCNN1G, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC27A1, SLC3A1, WNK1, WNT5A, ZMPSTE24	284	insoluble fraction

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005215	4.650e-10	28.27	70 ABCC2, ABCC4, ABCD3, AP1G1, AP1S3, AQP11, AQP3, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, CLCN5, CLDN16, CLIC3, CLIC6, CSE1L, CUBN, FLVCR1, GABRP, KCND3, KCNJ1, KCNJ16, KCNK5, M6PR, OSTalpha, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC25A16, SLC25A17, SLC25A48, SLC27A1, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC39A9, SLC3A1, SLC41A3, SLC46A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, SNX2, TRPM6, TRPM7, TRPV4, ZDHHC13	454	transporter activity
GO:0022857	6.426e-09	22.92	59 ABCC2, ABCC4, ABCD3, AQP3, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, CLCN5, CLDN16, CLIC3, CLIC6, GABRP, KCND3, KCNJ1, KCNJ16, KCNK5, M6PR, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC22A4, SLC25A10, SLC25A16, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC39A9, SLC3A1, SLC41A3, SLC46A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, TRPM6, TRPM7, TRPV4, ZDHHC13	368	transmembrane transporter activity
GO:0022804	1.721e-07	8.096	30 ABCC2, ABCC4, ABCD3, ATP13A3, ATP1B1, ATP6V0A4, ATP7A, CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC19A1, SLC1A1, SLC22A4, SLC25A16, SLC34A1, SLC3A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3	130	active transmembrane transporter activity
GO:0022892	2.432e-07	24.16	57 ABCC2, ABCC4, AP1G1, AP1S3, AQP3, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, CLCN5, CLDN16, CLIC3, CLIC6, CSE1L, GABRP, KCND3, KCNJ1, KCNJ16, KCNK5, M6PR, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC1A1, SLC22A4, SLC25A10, SLC27A1, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC39A9, SLC3A1, SLC41A3, SLC4A4, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, SNX2, TRPM6, TRPM7, TRPV4, ZDHHC13	388	substrate-specific transporter activity
GO:0022891	4.320e-07	21.3	52 ABCC2, ABCC4, AQP3, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, CLCN5, CLDN16, CLIC3, CLIC6, GABRP, KCND3, KCNJ1, KCNJ16, KCNK5, M6PR, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC18A1, SLC1A1, SLC22A4, SLC25A10, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC39A9, SLC3A1, SLC41A3, SLC4A4, SLC5A9, SLC6A19, SLC6A6, SLC7A9, SLC9A3, TRPM6, TRPM7, TRPV4, ZDHHC13	342	substrate-specific transmembrane transporter activity
GO:0022890	9.983e-06	4.795	20 ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, CLDN16, RHAG, RHCG, SLC10A2, SLC13A1, SLC13A3, SLC1A1, SLC22A4, SLC30A6, SLC31A1, SLC4A4, SLC5A9, SLC6A19, SLC6A6, SLC9A3, ZDHHC13	77	inorganic cation transmembrane transporter activity
GO:0015075	1.478e-05	18.68	44 ABCC2, ABCC4, ATP13A3, ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, CLCN5, CLDN16, CLIC3, CLIC6, GABRP, KCND3, KCNJ1, KCNJ16, KCNK5, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC17A5, SLC1A1, SLC22A4, SLC30A6, SLC30A7, SLC31A1, SLC34A1, SLC39A9, SLC41A3, SLC4A4, SLC5A9, SLC6A19, SLC6A6, SLC9A3, TRPM6, TRPM7, TRPV4, ZDHHC13	300	ion transmembrane transporter activity
GO:0008324	3.188e-05	14.14	36 ATP1B1, ATP6V0A4, ATP6V0D2, ATP7A, CLDN16, KCND3, KCNJ1, KCNJ16, KCNK5, PKD2, RASA3, RHAG, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC17A5, SLC1A1, SLC22A4, SLC30A6, SLC30A7, SLC31A1, SLC39A9, SLC41A3, SLC4A4, SLC5A9, SLC6A19, SLC6A6, SLC9A3, TRPM6, TRPM7, TRPV4, ZDHHC13	227	cation transmembrane transporter activity
GO:0015291	3.407e-05	5.231	20 CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC19A1, SLC1A1, SLC22A4, SLC25A16, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6, SLC9A3	84	secondary active transmembrane transporter activity
GO:0015293	4.204e-05	3.487	16 SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC1A1, SLC22A4, SLC34A1, SLC4A4, SLC5A11, SLC5A12, SLC5A9, SLC6A19, SLC6A6	56	symporter activity
GO:0046873	1.739e-04	3.487	15 ATP1B1, ATP7A, CLDN16, SLC10A2, SLC13A1, SLC13A3, SLC1A1, SLC30A6, SLC31A1, SLC39A9, SLC4A4, SLC5A9, SLC6A19, SLC6A6, ZDHHC13	56	metal ion transmembrane transporter activity
GO:0005342	1.586e-03	2.429	11 SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC1A1, SLC25A10, SLC3A1, SLC6A19, SLC6A6, SLC7A9	39	organic acid transmembrane transporter activity
GO:0046943	1.586e-03	2.429	11 SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC1A1, SLC25A10, SLC3A1, SLC6A19, SLC6A6, SLC7A9	39	carboxylic acid transmembrane transporter activity
GO:0019842	2.077e-03	3.425	13 CCBL1, CTH, CUBN, KL, MCCC1, MUT, OGFOD1, P4HTM, SLC19A1, SLC46A1, SPTLC2, TCN2, THNSL2	55	vitamin binding
GO:0008028	6.228e-03	0.5605	5 SLC10A2, SLC16A2, SLC16A4, SLC17A5, SLC6A6	9	monocarboxylic acid transmembrane transporter activity
GO:0015081	7.959e-03	2.055	9 ATP1B1, SLC10A2, SLC13A1, SLC13A3, SLC1A1, SLC4A4, SLC5A9, SLC6A19, SLC6A6	33	sodium ion transmembrane transporter activity
GO:0015077	9.094e-03	3.55	12 ATP1B1, ATP6V0A4, ATP6V0D2, SLC10A2, SLC13A1, SLC13A3, SLC1A1, SLC4A4, SLC5A9, SLC6A19, SLC6A6, SLC9A3	57	monovalent inorganic cation transmembrane transporter activity
GO:0016174	1.283e-02	0.1868	3 CYB5R4, KMO, NOX4	3	NAD(P)H oxidase activity
GO:0031419	1.283e-02	0.1868	3 CUBN, MUT, TCN2	3	cobalamin binding
GO:0015294	1.380e-02	2.242	9 SLC10A2, SLC13A1, SLC13A3, SLC17A5, SLC1A1, SLC4A4, SLC5A9, SLC6A19, SLC6A6	36	solute:cation symporter activity
GO:0008509	2.394e-02	4.048	12 ABCC2, ABCC4, CLCN5, CLIC3, CLIC6, GABRP, PKD2, SLC13A1, SLC13A3, SLC1A1, SLC34A1, SLC4A4	65	anion transmembrane transporter activity
GO:0005275	2.938e-02	2.055	8 SLC13A3, SLC18A1, SLC1A1, SLC22A4, SLC3A1, SLC6A19, SLC6A6, SLC7A9	33	amine transmembrane transporter activity
GO:0015101	3.482e-02	0.2491	3 RHAG, RHCG, SLC22A4	4	organic cation transmembrane transporter activity
GO:0015280	3.482e-02	0.2491	3 SCNN1A, SCNN1B, SCNN1G	4	amiloride-sensitive sodium channel activity
GO:0050664	3.482e-02	0.2491	3 CYB5R4, KMO, NOX4	4	oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor

Id	Pvalue	ExpCount	Count	Size	Term
04960	3.006e-03	1.081	7 ATP1B1, HSD11B2, KCNJ1, SCNN1A, SCNN1B, SCNN1G, SGK1	16	Aldosterone-regulated sodium reabsorption
04964	4.422e-03	0.5404	5 ATP1B1, PCK1, SLC25A10, SLC4A4, SLC9A3	8	Proximal tubule bicarbonate reclamation
04142	5.803e-03	3.445	12 AP1G1, AP1S3, ARSB, ASAH1, ATP6V0A4, ATP6V0D2, GLB1, LGMN, M6PR, NAGA, SLC17A5, TPP1	51	Lysosome

No enriched terms

No enriched terms

Entrez genes

A4GNTalpha-1,4-N-acetylglucosaminyltransferase (ENSG00000118017), score: 0.88 ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ENSG00000023839), score: 0.47 ABCC4ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ENSG00000125257), score: 0.73 ABCD3ATP-binding cassette, sub-family D (ALD), member 3 (ENSG00000117528), score: 0.56 ACMSDaminocarboxymuconate semialdehyde decarboxylase (ENSG00000153086), score: 0.51 ACO1aconitase 1, soluble (ENSG00000122729), score: 0.55 ADIPOR1adiponectin receptor 1 (ENSG00000159346), score: 0.52 AGPHD1aminoglycoside phosphotransferase domain containing 1 (ENSG00000188266), score: 0.65 AKAP6A kinase (PRKA) anchor protein 6 (ENSG00000151320), score: -0.53 AKR1A1aldo-keto reductase family 1, member A1 (aldehyde reductase) (ENSG00000117448), score: 0.63 AKR1D1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (ENSG00000122787), score: 0.47 ALDH6A1aldehyde dehydrogenase 6 family, member A1 (ENSG00000119711), score: 0.55 ALDH8A1aldehyde dehydrogenase 8 family, member A1 (ENSG00000118514), score: 0.5 ALDH9A1aldehyde dehydrogenase 9 family, member A1 (ENSG00000143149), score: 0.46 ANKLE2ankyrin repeat and LEM domain containing 2 (ENSG00000176915), score: -0.49 ANKRD13Cankyrin repeat domain 13C (ENSG00000118454), score: 0.59 ANKS4Bankyrin repeat and sterile alpha motif domain containing 4B (ENSG00000175311), score: 0.6 AP1G1adaptor-related protein complex 1, gamma 1 subunit (ENSG00000166747), score: 0.63 AP1S3adaptor-related protein complex 1, sigma 3 subunit (ENSG00000152056), score: 0.68 APEHN-acylaminoacyl-peptide hydrolase (ENSG00000164062), score: 0.54 AQP11aquaporin 11 (ENSG00000178301), score: 0.45 AQP3aquaporin 3 (Gill blood group) (ENSG00000165272), score: 0.66 ARFIP1ADP-ribosylation factor interacting protein 1 (ENSG00000164144), score: 0.55 ARHGEF38Rho guanine nucleotide exchange factor (GEF) 38 (ENSG00000138784), score: 0.74 ARSBarylsulfatase B (ENSG00000113273), score: 0.73 ARSKarylsulfatase family, member K (ENSG00000164291), score: 0.65 ASAH1N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ENSG00000104763), score: 0.54 ASPAaspartoacylase (ENSG00000108381), score: 0.76 ATP13A3ATPase type 13A3 (ENSG00000133657), score: 0.48 ATP1B1ATPase, Na+/K+ transporting, beta 1 polypeptide (ENSG00000143153), score: 0.52 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.8 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.54 ATP7AATPase, Cu++ transporting, alpha polypeptide (ENSG00000165240), score: 0.56 AVPR1Aarginine vasopressin receptor 1A (ENSG00000166148), score: 0.54 BCL10B-cell CLL/lymphoma 10 (ENSG00000142867), score: 0.49 BNC2basonuclin 2 (ENSG00000173068), score: 0.62 BPHLbiphenyl hydrolase-like (serine hydrolase) (ENSG00000137274), score: 0.47 BPNT13'(2'), 5'-bisphosphate nucleotidase 1 (ENSG00000162813), score: 0.78 BSPRYB-box and SPRY domain containing (ENSG00000119411), score: 0.56 C11orf54chromosome 11 open reading frame 54 (ENSG00000182919), score: 0.67 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.57 C1orf128chromosome 1 open reading frame 128 (ENSG00000057757), score: -0.5 C1orf83chromosome 1 open reading frame 83 (ENSG00000116205), score: 0.52 C7orf57chromosome 7 open reading frame 57 (ENSG00000164746), score: 0.51 C8orf42chromosome 8 open reading frame 42 (ENSG00000180190), score: 0.53 CA12carbonic anhydrase XII (ENSG00000074410), score: 0.6 CALML4calmodulin-like 4 (ENSG00000129007), score: 0.65 CAND2cullin-associated and neddylation-dissociated 2 (putative) (ENSG00000144712), score: -0.47 CAPRIN2caprin family member 2 (ENSG00000110888), score: -0.48 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.89 CCBL1cysteine conjugate-beta lyase, cytoplasmic (ENSG00000171097), score: 0.46 CCDC92coiled-coil domain containing 92 (ENSG00000119242), score: -0.46 CCND3cyclin D3 (ENSG00000112576), score: 0.52 CCNHcyclin H (ENSG00000134480), score: -0.54 CD82CD82 molecule (ENSG00000085117), score: 0.5 CDCP1CUB domain containing protein 1 (ENSG00000163814), score: 0.65 CELF2CUGBP, Elav-like family member 2 (ENSG00000048740), score: -0.54 CIRBPcold inducible RNA binding protein (ENSG00000099622), score: -0.49 CLCN5chloride channel 5 (ENSG00000171365), score: 0.63 CLDN16claudin 16 (ENSG00000113946), score: 0.79 CLDN19claudin 19 (ENSG00000164007), score: 0.92 CLEC3BC-type lectin domain family 3, member B (ENSG00000163815), score: -0.49 CLIC3chloride intracellular channel 3 (ENSG00000169583), score: 0.48 CLIC6chloride intracellular channel 6 (ENSG00000159212), score: 0.62 CLSTN3calsyntenin 3 (ENSG00000139182), score: -0.49 CLUclusterin (ENSG00000120885), score: -0.59 CNTN4contactin 4 (ENSG00000144619), score: -0.46 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.89 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.96 CRY2cryptochrome 2 (photolyase-like) (ENSG00000121671), score: -0.46 CSE1LCSE1 chromosome segregation 1-like (yeast) (ENSG00000124207), score: -0.46 CTHcystathionase (cystathionine gamma-lyase) (ENSG00000116761), score: 0.48 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.85 CYB5R4cytochrome b5 reductase 4 (ENSG00000065615), score: 0.45 CYTH1cytohesin 1 (ENSG00000108669), score: -0.46 CYTIPcytohesin 1 interacting protein (ENSG00000115165), score: 0.52 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.74 DAOD-amino-acid oxidase (ENSG00000110887), score: 0.66 DDA1DET1 and DDB1 associated 1 (ENSG00000130311), score: -0.48 DHDPSLdihydrodipicolinate synthase-like, mitochondrial (ENSG00000241935), score: 0.58 DMXL1Dmx-like 1 (ENSG00000172869), score: 0.52 DPEP1dipeptidase 1 (renal) (ENSG00000015413), score: 0.55 DPP4dipeptidyl-peptidase 4 (ENSG00000197635), score: 0.58 DRAM2DNA-damage regulated autophagy modulator 2 (ENSG00000156171), score: 0.47 E2F5E2F transcription factor 5, p130-binding (ENSG00000133740), score: 0.52 EDEM3ER degradation enhancer, mannosidase alpha-like 3 (ENSG00000116406), score: 0.5 EGFepidermal growth factor (ENSG00000138798), score: 0.9 EGFL6EGF-like-domain, multiple 6 (ENSG00000198759), score: 0.57 EHFets homologous factor (ENSG00000135373), score: 0.73 ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ENSG00000163435), score: 0.46 ENPEPglutamyl aminopeptidase (aminopeptidase A) (ENSG00000138792), score: 0.52 ENTPD6ectonucleoside triphosphate diphosphohydrolase 6 (putative) (ENSG00000197586), score: -0.51 EPCAMepithelial cell adhesion molecule (ENSG00000119888), score: 0.54 ERLIN1ER lipid raft associated 1 (ENSG00000107566), score: 0.45 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.74 EVCEllis van Creveld syndrome (ENSG00000072840), score: 0.62 EXOC3exocyst complex component 3 (ENSG00000180104), score: -0.5 EXOC6exocyst complex component 6 (ENSG00000138190), score: 0.47 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.64 FAM3Dfamily with sequence similarity 3, member D (ENSG00000198643), score: 0.54 FAM83Bfamily with sequence similarity 83, member B (ENSG00000168143), score: 0.6 FBXO31F-box protein 31 (ENSG00000103264), score: -0.51 FBXO4F-box protein 4 (ENSG00000151876), score: 0.51 FBXW4F-box and WD repeat domain containing 4 (ENSG00000107829), score: -0.48 FCHO2FCH domain only 2 (ENSG00000157107), score: 0.49 FERMT1fermitin family member 1 (ENSG00000101311), score: 0.75 FKBP9FK506 binding protein 9, 63 kDa (ENSG00000122642), score: 0.5 FLVCR1feline leukemia virus subgroup C cellular receptor 1 (ENSG00000162769), score: 0.48 FMN1formin 1 (ENSG00000186031), score: 0.56 FOXI1forkhead box I1 (ENSG00000168269), score: 0.69 FRAS1Fraser syndrome 1 (ENSG00000138759), score: 0.5 FSHBfollicle stimulating hormone, beta polypeptide (ENSG00000131808), score: 0.68 FZD4frizzled homolog 4 (Drosophila) (ENSG00000174804), score: 0.49 GABRPgamma-aminobutyric acid (GABA) A receptor, pi (ENSG00000094755), score: 0.54 GALK2galactokinase 2 (ENSG00000156958), score: 0.61 GALNT11UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (ENSG00000178234), score: 0.66 GALNT14UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (ENSG00000158089), score: 0.61 GALNTL1UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 (ENSG00000100626), score: -0.52 GARNL3GTPase activating Rap/RanGAP domain-like 3 (ENSG00000136895), score: -0.47 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.58 GCLMglutamate-cysteine ligase, modifier subunit (ENSG00000023909), score: 0.64 GCM1glial cells missing homolog 1 (Drosophila) (ENSG00000137270), score: 0.69 GLB1galactosidase, beta 1 (ENSG00000170266), score: 0.56 GPR160G protein-coupled receptor 160 (ENSG00000173890), score: 0.59 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.56 HECTD2HECT domain containing 2 (ENSG00000165338), score: -0.47 HEY1hairy/enhancer-of-split related with YRPW motif 1 (ENSG00000164683), score: -0.6 HNF1AHNF1 homeobox A (ENSG00000135100), score: 0.46 HNF4Ahepatocyte nuclear factor 4, alpha (ENSG00000101076), score: 0.55 HNF4Ghepatocyte nuclear factor 4, gamma (ENSG00000164749), score: 0.48 HOXA10homeobox A10 (ENSG00000153807), score: 0.71 HOXB7homeobox B7 (ENSG00000120087), score: 0.81 HOXD10homeobox D10 (ENSG00000128710), score: 0.7 HOXD4homeobox D4 (ENSG00000170166), score: 0.65 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.65 IDH1isocitrate dehydrogenase 1 (NADP+), soluble (ENSG00000138413), score: 0.5 IGFBP7insulin-like growth factor binding protein 7 (ENSG00000163453), score: 0.46 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.7 INPP5Binositol polyphosphate-5-phosphatase, 75kDa (ENSG00000204084), score: 0.5 IQGAP1IQ motif containing GTPase activating protein 1 (ENSG00000140575), score: 0.46 IRX2iroquois homeobox 2 (ENSG00000170561), score: 0.51 ITCHitchy E3 ubiquitin protein ligase homolog (mouse) (ENSG00000078747), score: 0.56 ITGA8integrin, alpha 8 (ENSG00000077943), score: 0.48 ITGB6integrin, beta 6 (ENSG00000115221), score: 0.72 ITGB8integrin, beta 8 (ENSG00000105855), score: 0.48 IVDisovaleryl-CoA dehydrogenase (ENSG00000128928), score: 0.46 IVNS1ABPinfluenza virus NS1A binding protein (ENSG00000116679), score: 0.52 IYDiodotyrosine deiodinase (ENSG00000009765), score: 0.46 JOSD1Josephin domain containing 1 (ENSG00000100221), score: -0.46 KCND3potassium voltage-gated channel, Shal-related subfamily, member 3 (ENSG00000171385), score: -0.5 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.77 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.74 KCNK5potassium channel, subfamily K, member 5 (ENSG00000164626), score: 0.61 KIAA1614KIAA1614 (ENSG00000135835), score: 0.5 KIF12kinesin family member 12 (ENSG00000136883), score: 0.46 KLklotho (ENSG00000133116), score: 0.81 KLHDC7Akelch domain containing 7A (ENSG00000179023), score: 0.58 KLHL14kelch-like 14 (Drosophila) (ENSG00000197705), score: 0.53 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (ENSG00000117009), score: 0.58 KRT23keratin 23 (histone deacetylase inducible) (ENSG00000108244), score: 0.59 KRT80keratin 80 (ENSG00000167767), score: 0.89 LAD1ladinin 1 (ENSG00000159166), score: 0.56 LAMC2laminin, gamma 2 (ENSG00000058085), score: 0.57 LAMC3laminin, gamma 3 (ENSG00000050555), score: 0.51 LDHDlactate dehydrogenase D (ENSG00000166816), score: 0.46 LGMNlegumain (ENSG00000100600), score: 0.76 LGR4leucine-rich repeat-containing G protein-coupled receptor 4 (ENSG00000205213), score: 0.52 LLGL2lethal giant larvae homolog 2 (Drosophila) (ENSG00000073350), score: 0.47 LPAR3lysophosphatidic acid receptor 3 (ENSG00000171517), score: 0.67 LRRC31leucine rich repeat containing 31 (ENSG00000114248), score: 0.54 LRRC58leucine rich repeat containing 58 (ENSG00000163428), score: 0.6 LYPD2LY6/PLAUR domain containing 2 (ENSG00000197353), score: 1 M6PRmannose-6-phosphate receptor (cation dependent) (ENSG00000003056), score: 0.54 MAN2B2mannosidase, alpha, class 2B, member 2 (ENSG00000013288), score: 0.53 MAP3K1mitogen-activated protein kinase kinase kinase 1 (ENSG00000095015), score: 0.61 MARVELD3MARVEL domain containing 3 (ENSG00000140832), score: 0.57 MCCC1methylcrotonoyl-CoA carboxylase 1 (alpha) (ENSG00000078070), score: 0.49 MCM4minichromosome maintenance complex component 4 (ENSG00000104738), score: -0.47 MEAF6MYST/Esa1-associated factor 6 (ENSG00000163875), score: -0.48 MEP1Ameprin A, alpha (PABA peptide hydrolase) (ENSG00000112818), score: 0.92 MEP1Bmeprin A, beta (ENSG00000141434), score: 0.84 MMP13matrix metallopeptidase 13 (collagenase 3) (ENSG00000137745), score: 0.47 MPDZmultiple PDZ domain protein (ENSG00000107186), score: -0.46 MPP1membrane protein, palmitoylated 1, 55kDa (ENSG00000130830), score: 0.66 MSRAmethionine sulfoxide reductase A (ENSG00000175806), score: 0.6 MUTmethylmalonyl CoA mutase (ENSG00000146085), score: 0.46 MYLIPmyosin regulatory light chain interacting protein (ENSG00000007944), score: 0.46 MYO6myosin VI (ENSG00000196586), score: 0.57 NAGAN-acetylgalactosaminidase, alpha- (ENSG00000198951), score: 0.58 NECAB3N-terminal EF-hand calcium binding protein 3 (ENSG00000125967), score: -0.49 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.86 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 0.52 NPNTnephronectin (ENSG00000168743), score: 0.57 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.71 NUDT19nudix (nucleoside diphosphate linked moiety X)-type motif 19 (ENSG00000213965), score: 0.53 OGFOD12-oxoglutarate and iron-dependent oxygenase domain containing 1 (ENSG00000087263), score: -0.49 OLFM4olfactomedin 4 (ENSG00000102837), score: 0.51 OPTNoptineurin (ENSG00000123240), score: -0.55 OSBPL3oxysterol binding protein-like 3 (ENSG00000070882), score: 0.75 OSBPL6oxysterol binding protein-like 6 (ENSG00000079156), score: 0.5 OSTalphaorganic solute transporter alpha (ENSG00000163959), score: 0.46 P4HTMprolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (ENSG00000178467), score: -0.67 PAFAH2platelet-activating factor acetylhydrolase 2, 40kDa (ENSG00000158006), score: 0.59 PANK1pantothenate kinase 1 (ENSG00000152782), score: 0.51 PAQR5progestin and adipoQ receptor family member V (ENSG00000137819), score: 0.56 PAQR9progestin and adipoQ receptor family member IX (ENSG00000188582), score: 0.5 PARP1poly (ADP-ribose) polymerase 1 (ENSG00000143799), score: -0.53 PARP6poly (ADP-ribose) polymerase family, member 6 (ENSG00000137817), score: -0.55 PCK1phosphoenolpyruvate carboxykinase 1 (soluble) (ENSG00000124253), score: 0.55 PEX11Aperoxisomal biogenesis factor 11 alpha (ENSG00000166821), score: 0.52 PGM3phosphoglucomutase 3 (ENSG00000013375), score: 0.64 PGPEP1pyroglutamyl-peptidase I (ENSG00000130517), score: 0.53 PHACTR4phosphatase and actin regulator 4 (ENSG00000204138), score: 0.46 PKD2polycystic kidney disease 2 (autosomal dominant) (ENSG00000118762), score: 0.68 PLAUplasminogen activator, urokinase (ENSG00000122861), score: 0.56 PLCXD2phosphatidylinositol-specific phospholipase C, X domain containing 2 (ENSG00000144824), score: 0.46 PLEKHF2pleckstrin homology domain containing, family F (with FYVE domain) member 2 (ENSG00000175895), score: 0.7 PLS1plastin 1 (ENSG00000120756), score: 0.75 PLXDC2plexin domain containing 2 (ENSG00000120594), score: 0.54 PPP1R13Bprotein phosphatase 1, regulatory (inhibitor) subunit 13B (ENSG00000088808), score: -0.54 PRLRprolactin receptor (ENSG00000113494), score: 0.79 PTERphosphotriesterase related (ENSG00000165983), score: 0.63 PYROXD2pyridine nucleotide-disulphide oxidoreductase domain 2 (ENSG00000119943), score: 0.76 RAB19RAB19, member RAS oncogene family (ENSG00000146955), score: 0.53 RAB3IPRAB3A interacting protein (rabin3) (ENSG00000127328), score: 0.51 RASA3RAS p21 protein activator 3 (ENSG00000185989), score: -0.46 RASSF6Ras association (RalGDS/AF-6) domain family member 6 (ENSG00000169435), score: 0.67 RBPMS2RNA binding protein with multiple splicing 2 (ENSG00000166831), score: 0.46 REEP1receptor accessory protein 1 (ENSG00000068615), score: -0.58 RHAGRh-associated glycoprotein (ENSG00000112077), score: 0.52 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.67 RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2 (ENSG00000071242), score: -0.49 SAMD4Asterile alpha motif domain containing 4A (ENSG00000020577), score: -0.53 SCINscinderin (ENSG00000006747), score: 0.47 SCNN1Asodium channel, nonvoltage-gated 1 alpha (ENSG00000111319), score: 0.62 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.71 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.66 SCRN1secernin 1 (ENSG00000136193), score: -0.46 SEC22CSEC22 vesicle trafficking protein homolog C (S. cerevisiae) (ENSG00000093183), score: -0.48 SETD7SET domain containing (lysine methyltransferase) 7 (ENSG00000145391), score: -0.48 SF3B3splicing factor 3b, subunit 3, 130kDa (ENSG00000189091), score: -0.5 SGK1serum/glucocorticoid regulated kinase 1 (ENSG00000118515), score: 0.45 SH3BP5SH3-domain binding protein 5 (BTK-associated) (ENSG00000131370), score: 0.58 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.74 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.94 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.69 SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (ENSG00000158296), score: 0.63 SLC16A12solute carrier family 16, member 12 (monocarboxylic acid transporter 12) (ENSG00000152779), score: 0.67 SLC16A2solute carrier family 16, member 2 (monocarboxylic acid transporter 8) (ENSG00000147100), score: 0.63 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.7 SLC17A5solute carrier family 17 (anion/sugar transporter), member 5 (ENSG00000119899), score: 0.59 SLC18A1solute carrier family 18 (vesicular monoamine), member 1 (ENSG00000036565), score: 0.59 SLC19A1solute carrier family 19 (folate transporter), member 1 (ENSG00000173638), score: 0.52 SLC1A1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 (ENSG00000106688), score: 0.49 SLC22A4solute carrier family 22 (organic cation/ergothioneine transporter), member 4 (ENSG00000197208), score: 0.74 SLC25A10solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 (ENSG00000183048), score: 0.53 SLC25A16solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 (ENSG00000122912), score: 0.46 SLC25A17solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 (ENSG00000100372), score: 0.56 SLC25A48solute carrier family 25, member 48 (ENSG00000145832), score: 0.64 SLC27A1solute carrier family 27 (fatty acid transporter), member 1 (ENSG00000130304), score: 0.47 SLC30A6solute carrier family 30 (zinc transporter), member 6 (ENSG00000152683), score: 0.55 SLC30A7solute carrier family 30 (zinc transporter), member 7 (ENSG00000162695), score: 0.52 SLC31A1solute carrier family 31 (copper transporters), member 1 (ENSG00000136868), score: 0.47 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.88 SLC37A3solute carrier family 37 (glycerol-3-phosphate transporter), member 3 (ENSG00000157800), score: 0.48 SLC39A9solute carrier family 39 (zinc transporter), member 9 (ENSG00000029364), score: 0.48 SLC3A1solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 (ENSG00000138079), score: 0.57 SLC41A3solute carrier family 41, member 3 (ENSG00000114544), score: -0.47 SLC46A1solute carrier family 46 (folate transporter), member 1 (ENSG00000076351), score: 0.5 SLC4A4solute carrier family 4, sodium bicarbonate cotransporter, member 4 (ENSG00000080493), score: 0.57 SLC5A11solute carrier family 5 (sodium/glucose cotransporter), member 11 (ENSG00000158865), score: 0.61 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.85 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 0.71 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.82 SLC6A6solute carrier family 6 (neurotransmitter transporter, taurine), member 6 (ENSG00000131389), score: 0.56 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.72 SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 3 (ENSG00000066230), score: 0.52 SNRPA1small nuclear ribonucleoprotein polypeptide A' (ENSG00000131876), score: -0.51 SNX2sorting nexin 2 (ENSG00000205302), score: 0.47 SPP1secreted phosphoprotein 1 (ENSG00000118785), score: 0.48 SPTLC2serine palmitoyltransferase, long chain base subunit 2 (ENSG00000100596), score: 0.67 SS18synovial sarcoma translocation, chromosome 18 (ENSG00000141380), score: 0.47 ST14suppression of tumorigenicity 14 (colon carcinoma) (ENSG00000149418), score: 0.52 STC1stanniocalcin 1 (ENSG00000159167), score: 0.5 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.79 SUSD3sushi domain containing 3 (ENSG00000157303), score: 0.5 SYDE2synapse defective 1, Rho GTPase, homolog 2 (C. elegans) (ENSG00000097096), score: 0.62 TBC1D22BTBC1 domain family, member 22B (ENSG00000065491), score: 0.5 TBC1D8TBC1 domain family, member 8 (with GRAM domain) (ENSG00000204634), score: -0.54 TBC1D8BTBC1 domain family, member 8B (with GRAM domain) (ENSG00000133138), score: 0.47 TCEA2transcription elongation factor A (SII), 2 (ENSG00000171703), score: -0.46 TCN2transcobalamin II (ENSG00000185339), score: 0.69 TECtec protein tyrosine kinase (ENSG00000135605), score: 0.56 TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta) (ENSG00000008196), score: 0.63 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.72 THNSL2threonine synthase-like 2 (S. cerevisiae) (ENSG00000144115), score: 0.55 TIMP3TIMP metallopeptidase inhibitor 3 (ENSG00000100234), score: 0.61 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.65 TMEM106Btransmembrane protein 106B (ENSG00000106460), score: 0.5 TMEM135transmembrane protein 135 (ENSG00000166575), score: 0.45 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.64 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.88 TMIGD1transmembrane and immunoglobulin domain containing 1 (ENSG00000182271), score: 0.84 TMPRSS2transmembrane protease, serine 2 (ENSG00000184012), score: 0.57 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (ENSG00000145779), score: 0.77 TPP1tripeptidyl peptidase I (ENSG00000166340), score: 0.46 TRIM7tripartite motif-containing 7 (ENSG00000146054), score: 0.49 TRPM6transient receptor potential cation channel, subfamily M, member 6 (ENSG00000119121), score: 0.83 TRPM7transient receptor potential cation channel, subfamily M, member 7 (ENSG00000092439), score: 0.57 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.73 TSHRthyroid stimulating hormone receptor (ENSG00000165409), score: 0.72 TTC36tetratricopeptide repeat domain 36 (ENSG00000172425), score: 0.52 TTLL7tubulin tyrosine ligase-like family, member 7 (ENSG00000137941), score: -0.47 UAP1L1UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 (ENSG00000197355), score: 0.64 UHRF1BP1LUHRF1 binding protein 1-like (ENSG00000111647), score: 0.47 UPB1ureidopropionase, beta (ENSG00000100024), score: 0.47 UPK3Auroplakin 3A (ENSG00000100373), score: 0.99 VASH1vasohibin 1 (ENSG00000071246), score: -0.53 VEZTvezatin, adherens junctions transmembrane protein (ENSG00000028203), score: -0.5 VPS39vacuolar protein sorting 39 homolog (S. cerevisiae) (ENSG00000166887), score: -0.48 VPS54vacuolar protein sorting 54 homolog (S. cerevisiae) (ENSG00000143952), score: 0.46 VWA2von Willebrand factor A domain containing 2 (ENSG00000165816), score: 0.54 WDR37WD repeat domain 37 (ENSG00000047056), score: -0.52 WDR72WD repeat domain 72 (ENSG00000166415), score: 0.48 WDR8WD repeat domain 8 (ENSG00000116213), score: -0.52 WNK1WNK lysine deficient protein kinase 1 (ENSG00000060237), score: 0.69 WNT5Awingless-type MMTV integration site family, member 5A (ENSG00000114251), score: 0.48 WRBtryptophan rich basic protein (ENSG00000182093), score: -0.58 XPNPEP1X-prolyl aminopeptidase (aminopeptidase P) 1, soluble (ENSG00000108039), score: 0.78 YTHDC2YTH domain containing 2 (ENSG00000047188), score: -0.52 ZBTB49zinc finger and BTB domain containing 49 (ENSG00000168826), score: -0.48 ZDHHC13zinc finger, DHHC-type containing 13 (ENSG00000177054), score: 0.57 ZEB1zinc finger E-box binding homeobox 1 (ENSG00000148516), score: -0.47 ZMPSTE24zinc metallopeptidase (STE24 homolog, S. cerevisiae) (ENSG00000084073), score: 0.46 ZNF750zinc finger protein 750 (ENSG00000141579), score: 0.51 ZPLD1zona pellucida-like domain containing 1 (ENSG00000170044), score: 0.95

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
oan_kd_m_ca1	oan	kd	m	_
mdo_kd_m_ca1	mdo	kd	m	_
oan_kd_f_ca1	oan	kd	f	_
mmu_kd_m2_ca1	mmu	kd	m	2
mmu_kd_f_ca1	mmu	kd	f	_
mmu_kd_m1_ca1	mmu	kd	m	1
mdo_kd_f_ca1	mdo	kd	f	_