Under-expression is coded with green,
over-expression with red color.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
cell-cell signaling
Any process that mediates the transfer of information from one cell to another.
synaptic transmission
The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
nervous system development
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
neurological system process
A organ system process carried out by any of the organs or tissues of neurological system.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
transmission of nerve impulse
The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.
signaling process
Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.
signaling
The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.
signal transmission
The process whereby a signal is released and/or conveyed from one location to another.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
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signaling process
Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
cell-cell signaling
Any process that mediates the transfer of information from one cell to another.
transmission of nerve impulse
The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
synaptic transmission
The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
transmission of nerve impulse
The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
dendrite
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
cation channel complex
An ion channel complex through which cations pass.
potassium channel complex
An ion channel complex through which potassium ions pass.
cell projection
A prolongation or process extending from a cell, e.g. a flagellum or axon.
neuron projection
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
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cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
inositol or phosphatidylinositol kinase activity
Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
ion channel activity
Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
voltage-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.
cation channel activity
Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
transmembrane transporter activity
Enables the transfer of a substance from one side of a membrane to the other.
cation transmembrane transporter activity
Catalysis of the transfer of cation from one side of the membrane to the other.
ion transmembrane transporter activity
Catalysis of the transfer of an ion from one side of a membrane to the other.
channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
kinase activity
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
transferase activity
Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
transferase activity, transferring phosphorus-containing groups
Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
passive transmembrane transporter activity
Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.
voltage-gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.
substrate-specific channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
voltage-gated cation channel activity
Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific transporter activity
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
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substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
ion channel activity
Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
cation channel activity
Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
voltage-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.
voltage-gated cation channel activity
Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.
ABCE1ATP-binding cassette, sub-family E (OABP), member 1 (ENSG00000164163), score: -0.59 ABHD12abhydrolase domain containing 12 (ENSG00000100997), score: 0.73 ABRactive BCR-related gene (ENSG00000159842), score: 0.7 ACTL6Aactin-like 6A (ENSG00000136518), score: -0.64 ADAMTS14ADAM metallopeptidase with thrombospondin type 1 motif, 14 (ENSG00000138316), score: 0.83 ADAMTS8ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ENSG00000134917), score: 0.79 ADCY2adenylate cyclase 2 (brain) (ENSG00000078295), score: 0.74 AIMP1aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 (ENSG00000164022), score: -0.58 ANKRD24ankyrin repeat domain 24 (ENSG00000089847), score: 0.81 AP3B1adaptor-related protein complex 3, beta 1 subunit (ENSG00000132842), score: -0.6 AP3M1adaptor-related protein complex 3, mu 1 subunit (ENSG00000185009), score: -0.63 ARCactivity-regulated cytoskeleton-associated protein (ENSG00000198576), score: 0.78 ARFIP1ADP-ribosylation factor interacting protein 1 (ENSG00000164144), score: -0.62 ARHGAP22Rho GTPase activating protein 22 (ENSG00000128805), score: 0.73 ASB6ankyrin repeat and SOCS box-containing 6 (ENSG00000148331), score: 0.75 ASXL2additional sex combs like 2 (Drosophila) (ENSG00000143970), score: -0.61 ATP13A2ATPase type 13A2 (ENSG00000159363), score: 0.79 ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b (ENSG00000117410), score: 0.74 BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 1 (ENSG00000156273), score: -0.64 BAI1brain-specific angiogenesis inhibitor 1 (ENSG00000181790), score: 0.77 BAP1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (ENSG00000163930), score: 0.88 BCL11BB-cell CLL/lymphoma 11B (zinc finger protein) (ENSG00000127152), score: 0.67 BEGAINbrain-enriched guanylate kinase-associated homolog (rat) (ENSG00000183092), score: 0.75 BTBD2BTB (POZ) domain containing 2 (ENSG00000133243), score: 0.71 C12orf53chromosome 12 open reading frame 53 (ENSG00000139200), score: 0.72 C13orf36chromosome 13 open reading frame 36 (ENSG00000180440), score: 0.73 C1orf128chromosome 1 open reading frame 128 (ENSG00000057757), score: 0.83 C1orf27chromosome 1 open reading frame 27 (ENSG00000157181), score: -0.59 C1orf55chromosome 1 open reading frame 55 (ENSG00000143751), score: -0.72 C20orf103chromosome 20 open reading frame 103 (ENSG00000125869), score: 0.68 C22orf9chromosome 22 open reading frame 9 (ENSG00000100364), score: 0.89 C8orf46chromosome 8 open reading frame 46 (ENSG00000169085), score: 0.83 C9orf16chromosome 9 open reading frame 16 (ENSG00000171159), score: 0.88 C9orf91chromosome 9 open reading frame 91 (ENSG00000157693), score: 0.72 CA7carbonic anhydrase VII (ENSG00000168748), score: 0.8 CABP1calcium binding protein 1 (ENSG00000157782), score: 0.71 CACNG3calcium channel, voltage-dependent, gamma subunit 3 (ENSG00000006116), score: 0.72 CALHM1calcium homeostasis modulator 1 (ENSG00000185933), score: 0.98 CAMK1Gcalcium/calmodulin-dependent protein kinase IG (ENSG00000008118), score: 0.83 CAMK2Acalcium/calmodulin-dependent protein kinase II alpha (ENSG00000070808), score: 0.78 CAMK2Gcalcium/calmodulin-dependent protein kinase II gamma (ENSG00000148660), score: 0.71 CAPN9calpain 9 (ENSG00000135773), score: 0.89 CBLN4cerebellin 4 precursor (ENSG00000054803), score: 0.82 CCDC3coiled-coil domain containing 3 (ENSG00000151468), score: 0.69 CCDC50coiled-coil domain containing 50 (ENSG00000152492), score: -0.68 CCM2cerebral cavernous malformation 2 (ENSG00000136280), score: 0.83 CD2APCD2-associated protein (ENSG00000198087), score: -0.64 CDH12cadherin 12, type 2 (N-cadherin 2) (ENSG00000154162), score: 0.72 CELF5CUGBP, Elav-like family member 5 (ENSG00000161082), score: 0.69 CETN3centrin, EF-hand protein, 3 (ENSG00000153140), score: -0.75 CHN1chimerin (chimaerin) 1 (ENSG00000128656), score: 0.74 CHRM3cholinergic receptor, muscarinic 3 (ENSG00000133019), score: 0.72 CHRNA4cholinergic receptor, nicotinic, alpha 4 (ENSG00000101204), score: 0.7 CHST1carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 (ENSG00000175264), score: 0.75 CLN5ceroid-lipofuscinosis, neuronal 5 (ENSG00000102805), score: -0.61 CNIH3cornichon homolog 3 (Drosophila) (ENSG00000143786), score: 0.76 COPB1coatomer protein complex, subunit beta 1 (ENSG00000129083), score: -0.65 COPB2coatomer protein complex, subunit beta 2 (beta prime) (ENSG00000184432), score: -0.63 CPNE4copine IV (ENSG00000196353), score: 0.67 CRHcorticotropin releasing hormone (ENSG00000147571), score: 0.72 CRTAC1cartilage acidic protein 1 (ENSG00000095713), score: 0.73 CTNND2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) (ENSG00000169862), score: 0.69 DAAM2dishevelled associated activator of morphogenesis 2 (ENSG00000146122), score: 0.74 DDX41DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (ENSG00000183258), score: 0.76 DDX51DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 (ENSG00000185163), score: 0.73 DERL2Der1-like domain family, member 2 (ENSG00000072849), score: -0.59 DGCR2DiGeorge syndrome critical region gene 2 (ENSG00000070413), score: 0.74 DGKZdiacylglycerol kinase, zeta 104kDa (ENSG00000149091), score: 0.85 DHX37DEAH (Asp-Glu-Ala-His) box polypeptide 37 (ENSG00000150990), score: 0.68 DLX1distal-less homeobox 1 (ENSG00000144355), score: 0.85 DNAJC10DnaJ (Hsp40) homolog, subfamily C, member 10 (ENSG00000077232), score: -0.66 DNAJC7DnaJ (Hsp40) homolog, subfamily C, member 7 (ENSG00000168259), score: 0.72 DPYSL4dihydropyrimidinase-like 4 (ENSG00000151640), score: 0.67 DRP2dystrophin related protein 2 (ENSG00000102385), score: 0.67 DSCAMDown syndrome cell adhesion molecule (ENSG00000171587), score: 0.7 DSCAML1Down syndrome cell adhesion molecule like 1 (ENSG00000177103), score: 0.69 EIF3Eeukaryotic translation initiation factor 3, subunit E (ENSG00000104408), score: -0.58 ELFN2extracellular leucine-rich repeat and fibronectin type III domain containing 2 (ENSG00000166897), score: 0.79 ELMOD2ELMO/CED-12 domain containing 2 (ENSG00000179387), score: -0.61 ENC1ectodermal-neural cortex 1 (with BTB-like domain) (ENSG00000171617), score: 0.86 ENTPD3ectonucleoside triphosphate diphosphohydrolase 3 (ENSG00000168032), score: 0.74 ENTPD6ectonucleoside triphosphate diphosphohydrolase 6 (putative) (ENSG00000197586), score: 0.71 EPHB6EPH receptor B6 (ENSG00000106123), score: 0.91 ETAA1Ewing tumor-associated antigen 1 (ENSG00000143971), score: -0.75 EXOC7exocyst complex component 7 (ENSG00000182473), score: 0.79 FAM102Afamily with sequence similarity 102, member A (ENSG00000167106), score: 0.74 FAM168Bfamily with sequence similarity 168, member B (ENSG00000152102), score: 0.71 FAM171A1family with sequence similarity 171, member A1 (ENSG00000148468), score: 0.68 FAM189A1family with sequence similarity 189, member A1 (ENSG00000104059), score: 0.67 FAM19A1family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 (ENSG00000183662), score: 0.79 FAM5Bfamily with sequence similarity 5, member B (ENSG00000198797), score: 0.8 FAM60Afamily with sequence similarity 60, member A (ENSG00000139146), score: -0.62 FBLN7fibulin 7 (ENSG00000144152), score: 0.9 FBXL15F-box and leucine-rich repeat protein 15 (ENSG00000107872), score: 0.77 FBXL16F-box and leucine-rich repeat protein 16 (ENSG00000127585), score: 0.78 FBXO2F-box protein 2 (ENSG00000116661), score: 0.71 FBXO30F-box protein 30 (ENSG00000118496), score: -0.58 FBXO8F-box protein 8 (ENSG00000164117), score: -0.64 FCHO2FCH domain only 2 (ENSG00000157107), score: -0.63 FEZF2FEZ family zinc finger 2 (ENSG00000153266), score: 0.99 FGF22fibroblast growth factor 22 (ENSG00000070388), score: 0.78 FNDC3Bfibronectin type III domain containing 3B (ENSG00000075420), score: -0.6 FOXG1forkhead box G1 (ENSG00000176165), score: 0.87 FRS3fibroblast growth factor receptor substrate 3 (ENSG00000137218), score: 0.71 GABPAGA binding protein transcription factor, alpha subunit 60kDa (ENSG00000154727), score: -0.79 GABRB3gamma-aminobutyric acid (GABA) A receptor, beta 3 (ENSG00000166206), score: 0.67 GJB5gap junction protein, beta 5, 31.1kDa (ENSG00000189280), score: 0.69 GJD4gap junction protein, delta 4, 40.1kDa (ENSG00000177291), score: 0.89 GLDNgliomedin (ENSG00000186417), score: 0.88 GNAZguanine nucleotide binding protein (G protein), alpha z polypeptide (ENSG00000128266), score: 0.7 GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1 (ENSG00000078369), score: 0.77 GOLGA4golgin A4 (ENSG00000144674), score: -0.75 GPR123G protein-coupled receptor 123 (ENSG00000197177), score: 0.85 GPR176G protein-coupled receptor 176 (ENSG00000166073), score: 0.75 GRID1glutamate receptor, ionotropic, delta 1 (ENSG00000182771), score: 0.74 GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 (ENSG00000176884), score: 0.71 GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A (ENSG00000183454), score: 0.67 GRM3glutamate receptor, metabotropic 3 (ENSG00000198822), score: 0.69 GSG1LGSG1-like (ENSG00000169181), score: 0.67 GXYLT1glucoside xylosyltransferase 1 (ENSG00000151233), score: -0.61 HAT1histone acetyltransferase 1 (ENSG00000128708), score: -0.64 HEATR5AHEAT repeat containing 5A (ENSG00000129493), score: -0.69 HGShepatocyte growth factor-regulated tyrosine kinase substrate (ENSG00000185359), score: 0.68 HIBCH3-hydroxyisobutyryl-CoA hydrolase (ENSG00000198130), score: -0.58 HMBOX1homeobox containing 1 (ENSG00000147421), score: -0.62 HRH2histamine receptor H2 (ENSG00000113749), score: 0.7 HRH3histamine receptor H3 (ENSG00000101180), score: 0.82 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (ENSG00000102468), score: 0.9 IDEinsulin-degrading enzyme (ENSG00000119912), score: -0.68 ITPK1inositol 1,3,4-triphosphate 5/6 kinase (ENSG00000100605), score: 0.75 ITPKAinositol 1,4,5-trisphosphate 3-kinase A (ENSG00000137825), score: 0.75 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (ENSG00000006459), score: -0.66 KCNA6potassium voltage-gated channel, shaker-related subfamily, member 6 (ENSG00000151079), score: 0.7 KCNF1potassium voltage-gated channel, subfamily F, member 1 (ENSG00000162975), score: 0.94 KCNG1potassium voltage-gated channel, subfamily G, member 1 (ENSG00000026559), score: 0.81 KCNG3potassium voltage-gated channel, subfamily G, member 3 (ENSG00000171126), score: 0.7 KCNH8potassium voltage-gated channel, subfamily H (eag-related), member 8 (ENSG00000183960), score: 0.86 KCNMB4potassium large conductance calcium-activated channel, subfamily M, beta member 4 (ENSG00000135643), score: 0.77 KCNQ2potassium voltage-gated channel, KQT-like subfamily, member 2 (ENSG00000075043), score: 0.75 KCNQ5potassium voltage-gated channel, KQT-like subfamily, member 5 (ENSG00000185760), score: 0.86 KCNS1potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 (ENSG00000124134), score: 0.92 KCNS2potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 (ENSG00000156486), score: 0.76 KCTD4potassium channel tetramerisation domain containing 4 (ENSG00000180332), score: 0.69 KDM5Alysine (K)-specific demethylase 5A (ENSG00000073614), score: -0.66 KIAA0020KIAA0020 (ENSG00000080608), score: -0.74 KIAA0284KIAA0284 (ENSG00000099814), score: 0.73 KIAA0427KIAA0427 (ENSG00000134030), score: 0.71 KIAA1797KIAA1797 (ENSG00000188352), score: 0.74 KIRREL3kin of IRRE like 3 (Drosophila) (ENSG00000149571), score: 0.71 KLHDC3kelch domain containing 3 (ENSG00000124702), score: 0.74 KLHL22kelch-like 22 (Drosophila) (ENSG00000099910), score: 0.75 KLHL26kelch-like 26 (Drosophila) (ENSG00000167487), score: 0.72 LACTBlactamase, beta (ENSG00000103642), score: -0.59 LAPTM4Alysosomal protein transmembrane 4 alpha (ENSG00000068697), score: -0.67 LBRlamin B receptor (ENSG00000143815), score: -0.62 LGR4leucine-rich repeat-containing G protein-coupled receptor 4 (ENSG00000205213), score: -0.69 LIMK1LIM domain kinase 1 (ENSG00000106683), score: 0.82 LMO4LIM domain only 4 (ENSG00000143013), score: 0.88 LNX2ligand of numb-protein X 2 (ENSG00000139517), score: -0.69 LPPR3lipid phosphate phosphatase-related protein type 3 (ENSG00000129951), score: 0.85 LPPR4lipid phosphate phosphatase-related protein type 4 (ENSG00000117600), score: 0.7 LRFN2leucine rich repeat and fibronectin type III domain containing 2 (ENSG00000156564), score: 0.85 LRP3low density lipoprotein receptor-related protein 3 (ENSG00000130881), score: 0.73 LRTM2leucine-rich repeats and transmembrane domains 2 (ENSG00000166159), score: 0.78 LYSMD3LysM, putative peptidoglycan-binding, domain containing 3 (ENSG00000176018), score: -0.69 MAP3K1mitogen-activated protein kinase kinase kinase 1 (ENSG00000095015), score: -0.77 MAPK8IP3mitogen-activated protein kinase 8 interacting protein 3 (ENSG00000138834), score: 0.7 MATKmegakaryocyte-associated tyrosine kinase (ENSG00000007264), score: 0.89 MATN1matrilin 1, cartilage matrix protein (ENSG00000162510), score: 0.74 MC4Rmelanocortin 4 receptor (ENSG00000166603), score: 0.69 MCEEmethylmalonyl CoA epimerase (ENSG00000124370), score: -0.58 MDM4Mdm4 p53 binding protein homolog (mouse) (ENSG00000198625), score: -0.71 MEF2Cmyocyte enhancer factor 2C (ENSG00000081189), score: 0.7 MGAT5Bmannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B (ENSG00000167889), score: 0.81 MIPEPmitochondrial intermediate peptidase (ENSG00000027001), score: -0.63 MKL1megakaryoblastic leukemia (translocation) 1 (ENSG00000196588), score: 0.73 MKL2MKL/myocardin-like 2 (ENSG00000186260), score: 0.73 MMAAmethylmalonic aciduria (cobalamin deficiency) cblA type (ENSG00000151611), score: -0.6 MTPAPmitochondrial poly(A) polymerase (ENSG00000107951), score: -0.74 MYNNmyoneurin (ENSG00000085274), score: -0.58 NCDNneurochondrin (ENSG00000020129), score: 0.78 NCS1neuronal calcium sensor 1 (ENSG00000107130), score: 0.68 NDPNorrie disease (pseudoglioma) (ENSG00000124479), score: 0.68 NEDD1neural precursor cell expressed, developmentally down-regulated 1 (ENSG00000139350), score: -0.63 NEFLneurofilament, light polypeptide (ENSG00000104725), score: 0.68 NELFnasal embryonic LHRH factor (ENSG00000165802), score: 0.73 NETO1neuropilin (NRP) and tolloid (TLL)-like 1 (ENSG00000166342), score: 0.79 NGEFneuronal guanine nucleotide exchange factor (ENSG00000066248), score: 0.73 NHLRC2NHL repeat containing 2 (ENSG00000196865), score: -0.69 NIPA1non imprinted in Prader-Willi/Angelman syndrome 1 (ENSG00000170113), score: 0.7 NPTNneuroplastin (ENSG00000156642), score: 0.67 NUDCD1NudC domain containing 1 (ENSG00000120526), score: -0.61 NUDCD3NudC domain containing 3 (ENSG00000015676), score: 0.74 OCA2oculocutaneous albinism II (ENSG00000104044), score: 1 OLFM1olfactomedin 1 (ENSG00000130558), score: 0.72 OPRL1opiate receptor-like 1 (ENSG00000125510), score: 0.82 PALMparalemmin (ENSG00000099864), score: 0.72 PANX2pannexin 2 (ENSG00000073150), score: 0.7 PCDH19protocadherin 19 (ENSG00000165194), score: 0.67 PCSK1proprotein convertase subtilisin/kexin type 1 (ENSG00000175426), score: 0.76 PDE6Bphosphodiesterase 6B, cGMP-specific, rod, beta (ENSG00000133256), score: 0.7 PDE8Bphosphodiesterase 8B (ENSG00000113231), score: 0.8 PDZD7PDZ domain containing 7 (ENSG00000186862), score: 0.75 PEX13peroxisomal biogenesis factor 13 (ENSG00000162928), score: -0.77 PIK3C2Aphosphoinositide-3-kinase, class 2, alpha polypeptide (ENSG00000011405), score: -0.63 PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta) (ENSG00000105647), score: 0.7 PIP4K2Aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha (ENSG00000150867), score: 0.68 PIP5K1Cphosphatidylinositol-4-phosphate 5-kinase, type I, gamma (ENSG00000186111), score: 0.68 PKP1plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) (ENSG00000081277), score: 0.8 PLCH1phospholipase C, eta 1 (ENSG00000114805), score: 0.73 PLEKHF2pleckstrin homology domain containing, family F (with FYVE domain) member 2 (ENSG00000175895), score: -0.61 PLEKHM2pleckstrin homology domain containing, family M (with RUN domain) member 2 (ENSG00000116786), score: 0.83 PMP2peripheral myelin protein 2 (ENSG00000147588), score: 0.69 POLD3polymerase (DNA-directed), delta 3, accessory subunit (ENSG00000077514), score: -0.58 POLR3Apolymerase (RNA) III (DNA directed) polypeptide A, 155kDa (ENSG00000148606), score: 0.84 PPARDperoxisome proliferator-activated receptor delta (ENSG00000112033), score: 0.72 PPME1protein phosphatase methylesterase 1 (ENSG00000214517), score: 0.7 PREX1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (ENSG00000124126), score: 0.7 PRKAA1protein kinase, AMP-activated, alpha 1 catalytic subunit (ENSG00000132356), score: -0.64 PRKAR1Bprotein kinase, cAMP-dependent, regulatory, type I, beta (ENSG00000188191), score: 0.75 PRMT8protein arginine methyltransferase 8 (ENSG00000111218), score: 0.67 PRPF19PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) (ENSG00000110107), score: 0.7 PRPF40APRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) (ENSG00000196504), score: -0.65 PSDpleckstrin and Sec7 domain containing (ENSG00000059915), score: 0.8 PTK2PTK2 protein tyrosine kinase 2 (ENSG00000169398), score: 0.68 RAB3CRAB3C, member RAS oncogene family (ENSG00000152932), score: 0.67 RAB40CRAB40C, member RAS oncogene family (ENSG00000197562), score: 0.97 RAI1retinoic acid induced 1 (ENSG00000108557), score: 0.69 RANGAP1Ran GTPase activating protein 1 (ENSG00000100401), score: 0.74 RASAL1RAS protein activator like 1 (GAP1 like) (ENSG00000111344), score: 0.74 RASD2RASD family, member 2 (ENSG00000100302), score: 0.68 RBP3retinol binding protein 3, interstitial (ENSG00000107618), score: 0.79 RESTRE1-silencing transcription factor (ENSG00000084093), score: -0.64 RHBDL3rhomboid, veinlet-like 3 (Drosophila) (ENSG00000141314), score: 0.73 RIMS3regulating synaptic membrane exocytosis 3 (ENSG00000117016), score: 0.74 ROCK1Rho-associated, coiled-coil containing protein kinase 1 (ENSG00000067900), score: -0.77 RORBRAR-related orphan receptor B (ENSG00000198963), score: 0.7 RP2retinitis pigmentosa 2 (X-linked recessive) (ENSG00000102218), score: -0.74 RRP15ribosomal RNA processing 15 homolog (S. cerevisiae) (ENSG00000067533), score: -0.58 RSPO2R-spondin 2 homolog (Xenopus laevis) (ENSG00000147655), score: 0.78 SARSseryl-tRNA synthetase (ENSG00000031698), score: 0.75 SATB2SATB homeobox 2 (ENSG00000119042), score: 0.73 SCN3Bsodium channel, voltage-gated, type III, beta (ENSG00000166257), score: 0.76 SCRG1stimulator of chondrogenesis 1 (ENSG00000164106), score: 0.7 SCYL2SCY1-like 2 (S. cerevisiae) (ENSG00000136021), score: -0.68 SEC23IPSEC23 interacting protein (ENSG00000107651), score: -0.61 SERPINI1serpin peptidase inhibitor, clade I (neuroserpin), member 1 (ENSG00000163536), score: 0.71 SGSM2small G protein signaling modulator 2 (ENSG00000141258), score: 0.75 SGSM3small G protein signaling modulator 3 (ENSG00000100359), score: 0.72 SIN3BSIN3 homolog B, transcription regulator (yeast) (ENSG00000127511), score: 0.73 SLC2A6solute carrier family 2 (facilitated glucose transporter), member 6 (ENSG00000160326), score: 0.82 SLC30A7solute carrier family 30 (zinc transporter), member 7 (ENSG00000162695), score: -0.61 SLC33A1solute carrier family 33 (acetyl-CoA transporter), member 1 (ENSG00000169359), score: -0.58 SLC6A7solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 (ENSG00000011083), score: 0.75 SMAD5SMAD family member 5 (ENSG00000113658), score: -0.73 SMEK1SMEK homolog 1, suppressor of mek1 (Dictyostelium) (ENSG00000100796), score: -0.62 SMNDC1survival motor neuron domain containing 1 (ENSG00000119953), score: -0.68 SNRNP48small nuclear ribonucleoprotein 48kDa (U11/U12) (ENSG00000168566), score: -0.64 SORCS1sortilin-related VPS10 domain containing receptor 1 (ENSG00000108018), score: 0.68 SOX8SRY (sex determining region Y)-box 8 (ENSG00000005513), score: 0.76 SPDEFSAM pointed domain containing ets transcription factor (ENSG00000124664), score: 0.9 SREBF2sterol regulatory element binding transcription factor 2 (ENSG00000198911), score: 0.76 SSTsomatostatin (ENSG00000157005), score: 0.79 ST6GALNAC5ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ENSG00000117069), score: 0.78 STMN4stathmin-like 4 (ENSG00000015592), score: 0.68 STOML1stomatin (EPB72)-like 1 (ENSG00000067221), score: 0.81 STRN3striatin, calmodulin binding protein 3 (ENSG00000196792), score: -0.58 SYF2SYF2 homolog, RNA splicing factor (S. cerevisiae) (ENSG00000117614), score: -0.59 SYNGR3synaptogyrin 3 (ENSG00000127561), score: 0.73 SYT17synaptotagmin XVII (ENSG00000103528), score: 0.8 TBL3transducin (beta)-like 3 (ENSG00000183751), score: 0.68 TDRD3tudor domain containing 3 (ENSG00000083544), score: -0.69 TGFBR1transforming growth factor, beta receptor 1 (ENSG00000106799), score: -0.76 THOC2THO complex 2 (ENSG00000125676), score: -0.59 TIAM2T-cell lymphoma invasion and metastasis 2 (ENSG00000146426), score: 0.67 TJAP1tight junction associated protein 1 (peripheral) (ENSG00000137221), score: 0.74 TMEM175transmembrane protein 175 (ENSG00000127419), score: 0.75 TMEM179transmembrane protein 179 (ENSG00000189203), score: 0.72 TMEM184Btransmembrane protein 184B (ENSG00000198792), score: 0.7 TMEM59Ltransmembrane protein 59-like (ENSG00000105696), score: 0.76 TMTC3transmembrane and tetratricopeptide repeat containing 3 (ENSG00000139324), score: -0.58 TOXthymocyte selection-associated high mobility group box (ENSG00000198846), score: 0.7 TP53INP1tumor protein p53 inducible nuclear protein 1 (ENSG00000164938), score: -0.62 TPPPtubulin polymerization promoting protein (ENSG00000171368), score: 0.75 TRMT61AtRNA methyltransferase 61 homolog A (S. cerevisiae) (ENSG00000166166), score: 0.77 TRPM2transient receptor potential cation channel, subfamily M, member 2 (ENSG00000142185), score: 0.8 TRPM7transient receptor potential cation channel, subfamily M, member 7 (ENSG00000092439), score: -0.82 TTC27tetratricopeptide repeat domain 27 (ENSG00000018699), score: -0.68 TUSC2tumor suppressor candidate 2 (ENSG00000114383), score: 0.7 UNC5Aunc-5 homolog A (C. elegans) (ENSG00000113763), score: 0.8 USO1USO1 vesicle docking protein homolog (yeast) (ENSG00000138768), score: -0.6 USP3ubiquitin specific peptidase 3 (ENSG00000140455), score: -0.66 USP53ubiquitin specific peptidase 53 (ENSG00000145390), score: -0.59 USP8ubiquitin specific peptidase 8 (ENSG00000138592), score: -0.68 VPS39vacuolar protein sorting 39 homolog (S. cerevisiae) (ENSG00000166887), score: 0.71 VPS54vacuolar protein sorting 54 homolog (S. cerevisiae) (ENSG00000143952), score: -0.68 VSTM2AV-set and transmembrane domain containing 2A (ENSG00000170419), score: 0.67 WDR37WD repeat domain 37 (ENSG00000047056), score: 0.71 WDR43WD repeat domain 43 (ENSG00000163811), score: -0.62 WEE1WEE1 homolog (S. pombe) (ENSG00000166483), score: -0.71 WNT7Awingless-type MMTV integration site family, member 7A (ENSG00000154764), score: 0.73 XRN15'-3' exoribonuclease 1 (ENSG00000114127), score: -0.64 XRN25'-3' exoribonuclease 2 (ENSG00000088930), score: -0.75 YARStyrosyl-tRNA synthetase (ENSG00000134684), score: 0.77 YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide (ENSG00000128245), score: 0.71 ZDHHC22zinc finger, DHHC-type containing 22 (ENSG00000177108), score: 0.76 ZER1zer-1 homolog (C. elegans) (ENSG00000160445), score: 0.76 ZFAND6zinc finger, AN1-type domain 6 (ENSG00000086666), score: -0.65 ZMAT4zinc finger, matrin type 4 (ENSG00000165061), score: 0.73 ZNF365zinc finger protein 365 (ENSG00000138311), score: 0.7
| Id | species | tissue | sex | individual |
|---|---|---|---|---|
| ptr_br_m5_ca1 | ptr | br | m | 5 |
| ptr_br_m3_ca1 | ptr | br | m | 3 |
| ggo_br_m_ca1 | ggo | br | m | _ |
| ptr_br_m2_ca1 | ptr | br | m | 2 |
| ppa_br_f1_ca1 | ppa | br | f | 1 |
| ppy_br_m_ca1 | ppy | br | m | _ |
| ptr_br_m1_ca1 | ptr | br | m | 1 |
| hsa_br_m3_ca1 | hsa | br | m | 3 |
| hsa_br_m7_ca1 | hsa | br | m | 7 |
