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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

cellular aldehyde metabolic process

The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

oxidation reduction

The process of removal or addition of one or more electrons with or without the concomitant removal or addition of a proton or protons.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

glycine metabolic process

The chemical reactions and pathways involving glycine, aminoethanoic acid.

vitamin metabolic process

The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.

water-soluble vitamin metabolic process

The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water.

nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

serine family amino acid metabolic process

The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.

amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

amine catabolic process

The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

organic acid transport

The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of, within or between cells by means of some external agent such as a transporter or pore.

organic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.

carboxylic acid metabolic process

The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

monocarboxylic acid metabolic process

The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

cellular amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

small molecule metabolic process

The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass.

small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.

carboxylic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.

carboxylic acid transport

The directed movement of carboxylic acids into, out of, within or between cells by means of some external agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

all

NA

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

cellular amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

organic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.

organic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

carboxylic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

sodium channel complex

An ion channel complex through which sodium ions pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

organic acid transmembrane transporter activity

Catalysis of the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other.

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

exopeptidase activity

Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

peptidase activity, acting on L-amino acid peptides

Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

lyase activity

Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.

vitamin binding

Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

carboxylic acid transmembrane transporter activity

Catalysis of the transfer of carboxylic acids from one side of the membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).

cofactor binding

Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.

coenzyme binding

Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0006082	1.222e-08	14.71	44 ACMSD, ACO1, ACOT12, ACSM3, ACSM5, AGXT, AKR1A1, ALDH6A1, ALDH8A1, ALDH9A1, AMDHD1, AVPR1A, BBOX1, CRYL1, CTH, DAO, DDC, DMGDH, DPYS, EHHADH, GATM, GGH, GLDC, HAO2, HGD, HNF1A, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, NR1H4, PAH, PCK1, PCK2, PEPD, PLP1, SARDH, SDSL, SGPL1, SLC25A10, SLC3A1, SLC7A9	228	organic acid metabolic process
GO:0019752	1.222e-08	14.71	44 ACMSD, ACO1, ACOT12, ACSM3, ACSM5, AGXT, AKR1A1, ALDH6A1, ALDH8A1, ALDH9A1, AMDHD1, AVPR1A, BBOX1, CRYL1, CTH, DAO, DDC, DMGDH, DPYS, EHHADH, GATM, GGH, GLDC, HAO2, HGD, HNF1A, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, NR1H4, PAH, PCK1, PCK2, PEPD, PLP1, SARDH, SDSL, SGPL1, SLC25A10, SLC3A1, SLC7A9	228	carboxylic acid metabolic process
GO:0043436	1.222e-08	14.71	44 ACMSD, ACO1, ACOT12, ACSM3, ACSM5, AGXT, AKR1A1, ALDH6A1, ALDH8A1, ALDH9A1, AMDHD1, AVPR1A, BBOX1, CRYL1, CTH, DAO, DDC, DMGDH, DPYS, EHHADH, GATM, GGH, GLDC, HAO2, HGD, HNF1A, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, NR1H4, PAH, PCK1, PCK2, PEPD, PLP1, SARDH, SDSL, SGPL1, SLC25A10, SLC3A1, SLC7A9	228	oxoacid metabolic process
GO:0042180	2.430e-08	15.03	44 ACMSD, ACO1, ACOT12, ACSM3, ACSM5, AGXT, AKR1A1, ALDH6A1, ALDH8A1, ALDH9A1, AMDHD1, AVPR1A, BBOX1, CRYL1, CTH, DAO, DDC, DMGDH, DPYS, EHHADH, GATM, GGH, GLDC, HAO2, HGD, HNF1A, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, NR1H4, PAH, PCK1, PCK2, PEPD, PLP1, SARDH, SDSL, SGPL1, SLC25A10, SLC3A1, SLC7A9	233	cellular ketone metabolic process
GO:0007588	2.236e-07	1.549	13 AQP3, ATP6V0A4, AVPR1A, CLCN5, CLDN16, DAB2, KCNJ1, KCNK5, NPHS2, NPR3, SCNN1A, SCNN1B, SCNN1G	24	excretion
GO:0006519	1.184e-06	8.517	29 AGXT, ALDH6A1, ALDH9A1, AMDHD1, BBOX1, BPHL, CTH, DAO, DDC, DMGDH, DPYS, ETNK2, GATM, GGH, GLDC, HGD, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, PAH, PEPD, SARDH, SDSL, SLC3A1, SLC7A9, TPMT	132	cellular amino acid and derivative metabolic process
GO:0044106	1.098e-05	7.356	25 AGXT, ALDH6A1, ALDH9A1, AMDHD1, BBOX1, CTH, DAO, DDC, DMGDH, DPYS, ETNK2, GGH, GLDC, HGD, HNF4A, IVD, KMO, MCCC1, MSRA, PAH, PEPD, SARDH, SDSL, SLC3A1, SLC7A9	114	cellular amine metabolic process
GO:0006520	3.734e-05	5.807	21 AGXT, ALDH6A1, AMDHD1, CTH, DAO, DMGDH, DPYS, GGH, GLDC, HGD, HNF4A, IVD, KMO, MCCC1, MSRA, PAH, PEPD, SARDH, SDSL, SLC3A1, SLC7A9	90	cellular amino acid metabolic process
GO:0009308	1.554e-04	9.743	27 AGXT, ALDH6A1, ALDH9A1, AMDHD1, BBOX1, CTBS, CTH, DAO, DDC, DMGDH, DPYS, ETNK2, GATM, GGH, GLDC, HGD, HNF4A, IVD, KMO, MCCC1, MSRA, PAH, PEPD, SARDH, SDSL, SLC3A1, SLC7A9	151	amine metabolic process
GO:0055114	5.907e-04	12.45	30 AKR1A1, ALDH2, ALDH6A1, ALDH8A1, ALDH9A1, BBOX1, CRYL1, CYB5A, CYBASC3, DAO, DECR2, DHRS3, DHTKD1, DMGDH, EHHADH, GLDC, HAO2, HGD, HSD11B2, IDH1, IVD, IYD, KMO, LDHD, MSRA, NOX4, PAH, PYROXD2, SARDH, SUMF1	193	oxidation reduction
GO:0009063	6.947e-04	1.807	10 ALDH6A1, AMDHD1, DMGDH, GLDC, HGD, IVD, KMO, MCCC1, PAH, SARDH	28	cellular amino acid catabolic process
GO:0009310	9.416e-04	1.871	10 ALDH6A1, AMDHD1, DMGDH, GLDC, HGD, IVD, KMO, MCCC1, PAH, SARDH	29	amine catabolic process
GO:0055085	1.522e-03	17.94	37 ABCC2, ABCC8, AQP3, ATP6V0A4, ATP6V0D2, ATP6V0E1, CACNA1C, CDH1, CLCN5, EGF, HCN4, ITPR2, PDIA3, PLCG2, RHCG, RRBP1, RYR2, SFXN2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC25A10, SLC26A7, SLC2A2, SLC2A9, SLC39A9, SLC45A3, SLC5A12, SLC5A9, SLC7A9, SLC9A3R1, TRPM6, TRPV4	278	transmembrane transport
GO:0006544	1.911e-03	0.2581	4 AGXT, DMGDH, GLDC, SARDH	4	glycine metabolic process
GO:0006812	1.951e-03	14.71	32 ABCC8, ATP6V0A4, ATP6V0D2, ATP6V0E1, CACNA1C, EGF, HCN4, ITPR2, KCNJ1, KCNJ16, KCNK5, PLCG2, RHCG, RYR2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC31A1, SLC34A1, SLC38A10, SLC39A9, SLC40A1, SLC5A12, SLC5A9, SLC9A3R1, TCN2, TRPM6, TRPV4	228	cation transport
GO:0044281	2.006e-03	38.84	64 ACMSD, ACO1, ACOT12, ACSM3, ACSM5, AGXT, AKR1A1, ALDH2, ALDH6A1, ALDH8A1, ALDH9A1, AMDHD1, ATP6V0A4, ATP6V0D2, ATP6V0E1, AVPR1A, BBOX1, BPHL, CA12, CRYL1, CTH, CUBN, DAK, DAO, DDC, DHRS3, DHTKD1, DMGDH, DPYS, EHHADH, ETNK2, GALK1, GALK2, GATM, GGH, GLDC, HAO2, HGD, HNF1A, HNF4A, IDH1, IVD, KMO, MCCC1, MSRA, NAPRT1, NPR3, NR1H4, PAH, PANK1, PCK1, PCK2, PEPD, PLCG2, PLP1, POFUT1, RBKS, SARDH, SDSL, SGPL1, SLC25A10, SLC3A1, SLC7A9, TPMT	602	small molecule metabolic process
GO:0009069	2.204e-03	0.4517	5 AGXT, CTH, DMGDH, GLDC, SARDH	7	serine family amino acid metabolic process
GO:0016054	3.414e-03	3.097	12 AKR1A1, ALDH6A1, AMDHD1, DMGDH, GLDC, HAO2, HGD, IVD, KMO, MCCC1, PAH, SARDH	48	organic acid catabolic process
GO:0046395	3.414e-03	3.097	12 AKR1A1, ALDH6A1, AMDHD1, DMGDH, GLDC, HAO2, HGD, IVD, KMO, MCCC1, PAH, SARDH	48	carboxylic acid catabolic process
GO:0032787	4.813e-03	8.259	21 ACOT12, ACSM3, ACSM5, AGXT, AKR1A1, ALDH8A1, ALDH9A1, AVPR1A, BBOX1, CRYL1, DAO, EHHADH, HAO2, HNF1A, IDH1, MCCC1, NR1H4, PCK1, PCK2, PLP1, SLC25A10	128	monocarboxylic acid metabolic process
GO:0015849	7.596e-03	4.452	14 AGXT, HNF1A, SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC25A10, SLC26A7, SLC38A10, SLC3A1, SLC6A19, SLC7A9, THBS1	69	organic acid transport
GO:0046942	7.596e-03	4.452	14 AGXT, HNF1A, SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC25A10, SLC26A7, SLC38A10, SLC3A1, SLC6A19, SLC7A9, THBS1	69	carboxylic acid transport
GO:0006081	9.712e-03	0.9033	6 AGXT, AKR1A1, ALDH8A1, ALDH9A1, DAO, IDH1	14	cellular aldehyde metabolic process
GO:0006767	9.712e-03	0.9033	6 AKR1A1, ALDH9A1, BBOX1, KMO, MCCC1, NAPRT1	14	water-soluble vitamin metabolic process
GO:0015672	1.561e-02	7.227	18 ABCC8, ATP6V0A4, ATP6V0D2, ATP6V0E1, KCNJ1, KCNJ16, KCNK5, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC34A1, SLC38A10, SLC5A12, SLC5A9, SLC9A3R1	112	monovalent inorganic cation transport
GO:0006546	1.669e-02	0.1936	3 DMGDH, GLDC, SARDH	3	glycine catabolic process
GO:0006551	1.669e-02	0.1936	3 DAO, IVD, MCCC1	3	leucine metabolic process
GO:0006766	1.694e-02	1.807	8 AKR1A1, ALDH8A1, ALDH9A1, BBOX1, DHRS3, KMO, MCCC1, NAPRT1	28	vitamin metabolic process
GO:0030001	2.119e-02	12.84	26 ABCC8, CACNA1C, EGF, ITPR2, KCNJ1, KCNJ16, KCNK5, PLCG2, RYR2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC31A1, SLC34A1, SLC38A10, SLC39A9, SLC40A1, SLC5A12, SLC5A9, TCN2, TRPM6, TRPV4	199	metal ion transport
GO:0042221	2.155e-02	33.68	53 ACO1, AGXT, ALDH2, AQP3, ARSB, ATP6V0E1, AVPR1A, BPHL, BTRC, CASP6, CASR, CDH1, COL4A3, CTSH, CUBN, DDC, DPP4, EDEM1, EPHX2, ERBB2, ESR1, F2RL1, FZD4, GATA3, GATM, GGH, HDAC9, HNF1A, HNF4A, HSD11B2, IDH1, IGFBP7, IHH, ITGA1, ITPR2, MAP1B, MSRA, NAPRT1, NR1H4, PCK1, PCK2, PLCG2, RYR2, SCNN1B, SCNN1G, SERPINF2, SGK2, SLC34A1, SLC6A19, THBS1, TPMT, TRIB1, TRPM6	522	response to chemical stimulus
GO:0032026	2.696e-02	0.4517	4 PLCG2, RYR2, SLC34A1, THBS1	7	response to magnesium ion
GO:0030855	2.900e-02	4.065	12 AQP3, EHF, ELF3, ELF5, ESR1, IHH, IRF6, RHCG, SALL1, TCF21, TFCP2L1, ZEB1	63	epithelial cell differentiation
GO:0006811	2.923e-02	21.42	37 ABCC8, ATP6V0A4, ATP6V0D2, ATP6V0E1, CACNA1C, CLCN5, CLDN16, EGF, HCN4, ITPR2, KCNJ1, KCNJ16, KCNK5, PLCG2, RHCG, RYR2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC17A5, SLC22A7, SLC26A7, SLC31A1, SLC34A1, SLC38A10, SLC39A9, SLC40A1, SLC5A12, SLC5A9, SLC9A3R1, TCN2, TRPM6, TRPV4	332	ion transport
GO:0006814	3.232e-02	3.033	10 SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC34A1, SLC38A10, SLC5A12, SLC5A9	47	sodium ion transport
GO:0009081	4.317e-02	0.5162	4 ALDH6A1, DAO, IVD, MCCC1	8	branched chain family amino acid metabolic process
GO:0019439	4.317e-02	0.5162	4 EPHX2, HGD, KMO, PAH	8	aromatic compound catabolic process
GO:0048545	4.321e-02	6.13	15 AGXT, ALDH2, ARSB, AVPR1A, CASP6, ERBB2, ESR1, GATA3, HSD11B2, IGFBP7, IHH, MAP1B, PCK2, THBS1, TPMT	95	response to steroid hormone stimulus
GO:0006575	4.376e-02	3.742	11 ALDH9A1, BBOX1, CTH, DDC, DMGDH, ETNK2, GATM, IDH1, KMO, PAH, TPMT	58	cellular amino acid derivative metabolic process
GO:0009071	4.462e-02	0.2581	3 DMGDH, GLDC, SARDH	4	serine family amino acid catabolic process
GO:0016338	4.462e-02	0.2581	3 CLDN1, CLDN16, CLDN19	4	calcium-independent cell-cell adhesion
GO:0046487	4.462e-02	0.2581	3 AGXT, DAO, IDH1	4	glyoxylate metabolic process

Id	Pvalue	ExpCount	Count	Size	Term
GO:0045177	5.015e-08	4.624	22 ABCC2, AKR1A1, ATP6V0A4, ATP6V0D2, CDH1, CLCN5, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, LGMN, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC5A12, SLC9A3R1, TRPM6	75	apical part of cell
GO:0016324	1.292e-07	3.637	19 ABCC2, AKR1A1, ATP6V0A4, ATP6V0D2, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC5A12, SLC9A3R1, TRPM6	59	apical plasma membrane
GO:0044459	6.783e-05	44.45	75 ABCC2, ADAM23, AKR1A1, AQP3, ARHGAP26, ATP6V0A4, ATP6V0D2, AVPR1A, CACNA1C, CAMK2A, CASR, CDH1, CLCN5, CLDN1, CLDN16, CLDN19, CTNND2, CUBN, DPEP1, DPP4, DTNA, ENPEP, EPCAM, EPHA1, ERBB2, ESR1, F2RL1, FGFR4, FZD4, FZD5, GJB1, GPRC5C, IL13RA1, ITGA1, KCNJ1, KCNJ16, KCNK5, KL, LRP8, MARVELD2, MYH9, MYO1D, NOX4, NPHS2, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC26A7, SLC2A2, SLC2A9, SLC31A1, SLC34A1, SLC3A1, SLC40A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3R1, SPTB, ST14, THBS1, TJP3, TMPRSS2, TNFSF10, TNFSF15, TRPM6, TRPV4	721	plasma membrane part
GO:0005886	9.808e-04	69.85	100 ABCC2, ACE2, ADAM23, AKR1A1, ANKS4B, AQP3, ARHGAP26, ATP6V0A4, ATP6V0D2, AVPR1A, CACNA1C, CAMK2A, CASR, CCDC88A, CDCP1, CDH1, CLCN5, CLDN1, CLDN16, CLDN19, CTNND1, CTNND2, CUBN, DPEP1, DPP4, DTNA, EGF, ENPEP, EPCAM, EPHA1, ERBB2, ESR1, F2RL1, FGFR4, FZD4, FZD5, GJB1, GPR160, GPRC5C, IHH, IL13RA1, ILDR1, ITGA1, IYD, KCNJ1, KCNJ16, KCNK5, KL, LGR4, LRP8, MAP1B, MARVELD2, MYH9, MYO1D, NOX4, NPHS2, NTM, OSTalpha, PAWR, PLCG2, PROM2, RAB17, RAB19, RAB7L1, RAB9B, RHCG, RYR2, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC26A7, SLC2A2, SLC2A9, SLC31A1, SLC34A1, SLC3A1, SLC40A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3R1, SPTB, ST14, THBS1, TJP3, TMPRSS2, TNFSF10, TNFSF15, TRPM6, TRPV4, XPNPEP2	1133	plasma membrane
GO:0005903	1.737e-03	1.11	7 ATP6V0A4, CUBN, ENPEP, SLC13A1, SLC2A2, SLC34A1, TRPM6	18	brush border
GO:0034706	5.639e-03	0.1849	3 SCNN1A, SCNN1B, SCNN1G	3	sodium channel complex
GO:0005773	9.230e-03	5.672	15 ARSB, ATP6V0A4, ATP6V0D2, CLN5, CTBS, CTSH, CUBN, CYBASC3, FAM176A, GGH, GLB1, LGMN, SLC17A5, SLC3A1, TPP1	92	vacuole
GO:0031526	1.421e-02	0.8014	5 ATP6V0A4, CUBN, SLC2A2, SLC34A1, TRPM6	13	brush border membrane
GO:0031253	1.811e-02	2.651	9 ATP6V0A4, CUBN, DPEP1, DPP4, MYO1D, PROM2, SLC2A2, SLC34A1, TRPM6	43	cell projection membrane
GO:0005739	2.246e-02	26.32	42 ACSM3, ACSM5, ACSS3, AGXT, AK2, ALDH2, ALDH6A1, ALDH9A1, ARSB, BBOX1, BPHL, CYB5A, DHDPSL, DHTKD1, DMGDH, DUSP26, ECHDC3, EHHADH, GATM, GLDC, GLYCTK, GPRC5C, HAO2, IDH1, IVD, KMO, LAP3, LDHD, MCCC1, MSRA, NIPSNAP1, NIT2, PCK2, REEP1, SACS, SARDH, SDSL, SFXN2, SLC25A10, SLC3A1, TDRKH, TPP1	427	mitochondrion
GO:0031226	3.145e-02	26.08	41 ABCC2, ADAM23, AVPR1A, CASR, CLCN5, CLDN1, ENPEP, EPHA1, F2RL1, FGFR4, FZD4, FZD5, GPRC5C, IL13RA1, ITGA1, KCNJ1, KCNJ16, KCNK5, KL, MYH9, NPHS2, RHCG, SCNN1G, SLC10A2, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC2A2, SLC2A9, SLC31A1, SLC34A1, SLC3A1, SLC40A1, SLC6A19, SLC7A9, SPTB, ST14, TMPRSS2, TNFSF10, TNFSF15	423	intrinsic to plasma membrane
GO:0000323	3.282e-02	4.685	12 ARSB, CLN5, CTBS, CTSH, CUBN, CYBASC3, FAM176A, GGH, GLB1, LGMN, SLC17A5, TPP1	76	lytic vacuole
GO:0005764	3.282e-02	4.685	12 ARSB, CLN5, CTBS, CTSH, CUBN, CYBASC3, FAM176A, GGH, GLB1, LGMN, SLC17A5, TPP1	76	lysosome
GO:0005887	3.482e-02	25.46	40 ABCC2, ADAM23, AVPR1A, CASR, CLCN5, CLDN1, ENPEP, EPHA1, F2RL1, FGFR4, FZD4, FZD5, GPRC5C, IL13RA1, ITGA1, KCNJ1, KCNJ16, KCNK5, KL, MYH9, NPHS2, RHCG, SCNN1G, SLC10A2, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC2A2, SLC2A9, SLC31A1, SLC34A1, SLC3A1, SLC40A1, SLC6A19, SLC7A9, ST14, TMPRSS2, TNFSF10, TNFSF15	413	integral to plasma membrane
GO:0005911	3.874e-02	4.192	11 ABCC2, AQP3, CDH1, CLDN1, CLDN16, CLDN19, DPP4, GJB1, MARVELD2, MYH9, TJP3	68	cell-cell junction
GO:0005777	4.648e-02	2.034	7 AGXT, DAO, DECR2, EHHADH, EPHX2, HAO2, IDH1	33	peroxisome
GO:0042579	4.648e-02	2.034	7 AGXT, DAO, DECR2, EHHADH, EPHX2, HAO2, IDH1	33	microbody

Id	Pvalue	ExpCount	Count	Size	Term
GO:0048037	3.490e-06	5.38	22 AGXT, ALDH6A1, ALDH9A1, CRYL1, CTH, DDC, DHTKD1, DMGDH, EHHADH, GLDC, HAO2, HSD11B2, IDH1, IVD, KMO, LDHD, NOX4, PAH, SARDH, SDSL, SGPL1, THNSL2	83	cofactor binding
GO:0008238	1.387e-03	2.398	11 ACE2, DPEP1, DPP4, ENPEP, GGH, LAP3, PEPD, SCRN2, TMEM27, TPP1, XPNPEP2	37	exopeptidase activity
GO:0022857	1.590e-03	23.85	45 ABCC2, ABCC8, AQP3, ATP6V0A4, ATP6V0D2, ATP6V0E1, CACNA1C, CLCN5, CLDN16, CYB5A, GJB1, HCN4, ITPR2, KCNJ1, KCNJ16, KCNK5, RHCG, RYR2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC25A10, SLC26A7, SLC2A2, SLC2A9, SLC31A1, SLC34A1, SLC39A9, SLC3A1, SLC40A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, TRPM6, TRPV4	368	transmembrane transporter activity
GO:0050662	1.594e-03	3.824	14 ALDH6A1, ALDH9A1, CRYL1, DHTKD1, DMGDH, EHHADH, HAO2, HSD11B2, IDH1, IVD, KMO, LDHD, NOX4, SARDH	59	coenzyme binding
GO:0016491	1.609e-03	13.29	30 AKR1A1, ALDH2, ALDH6A1, ALDH8A1, ALDH9A1, BBOX1, CRYL1, CYB5A, CYBASC3, DAO, DECR2, DHRS3, DHTKD1, DMGDH, EHHADH, GLDC, HAO2, HGD, HSD11B2, IDH1, IVD, IYD, KMO, LDHD, MSRA, NOX4, PAH, PYROXD2, SARDH, SUMF1	205	oxidoreductase activity
GO:0022891	2.511e-03	22.17	42 ABCC2, ABCC8, AQP3, ATP6V0A4, ATP6V0D2, ATP6V0E1, CACNA1C, CLCN5, CLDN16, CYB5A, HCN4, ITPR2, KCNJ1, KCNJ16, KCNK5, RHCG, RYR2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC25A10, SLC26A7, SLC2A2, SLC2A9, SLC31A1, SLC34A1, SLC39A9, SLC3A1, SLC40A1, SLC5A9, SLC6A19, SLC7A9, TRPM6, TRPV4	342	substrate-specific transmembrane transporter activity
GO:0019842	2.839e-03	3.565	13 AGXT, CTH, CUBN, DDC, DHTKD1, DMGDH, GLDC, KL, MCCC1, SDSL, SGPL1, TCN2, THNSL2	55	vitamin binding
GO:0016829	3.393e-03	4.148	14 ACMSD, ACO1, CA12, CTH, DAK, DDC, DHDPSL, EHHADH, GLDC, PCK1, PCK2, SDSL, SGPL1, THNSL2	64	lyase activity
GO:0022804	5.259e-03	8.426	21 ABCC2, ABCC8, ATP6V0A4, ATP6V0E1, CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC26A7, SLC2A9, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9	130	active transmembrane transporter activity
GO:0022890	6.340e-03	4.991	15 ABCC8, ATP6V0A4, ATP6V0D2, ATP6V0E1, CLDN16, CYB5A, ITPR2, RHCG, SLC10A2, SLC13A1, SLC13A3, SLC31A1, SLC40A1, SLC5A9, SLC6A19	77	inorganic cation transmembrane transporter activity
GO:0008324	7.389e-03	14.71	30 ABCC8, ATP6V0A4, ATP6V0D2, ATP6V0E1, CACNA1C, CLDN16, CYB5A, HCN4, ITPR2, KCNJ1, KCNJ16, KCNK5, RHCG, RYR2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC17A5, SLC2A9, SLC31A1, SLC39A9, SLC40A1, SLC5A9, SLC6A19, TRPM6, TRPV4	227	cation transmembrane transporter activity
GO:0022892	7.933e-03	25.15	44 ABCC2, ABCC8, AP1S3, AQP3, ATP6V0A4, ATP6V0D2, ATP6V0E1, CACNA1C, CLCN5, CLDN16, CYB5A, HCN4, ITPR2, KCNJ1, KCNJ16, KCNK5, RHCG, RYR2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC25A10, SLC26A7, SLC2A2, SLC2A9, SLC31A1, SLC34A1, SLC39A9, SLC3A1, SLC40A1, SLC5A9, SLC6A19, SLC7A9, SNX2, TRPM6, TRPV4	388	substrate-specific transporter activity
GO:0005342	8.215e-03	2.528	10 SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC25A10, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	organic acid transmembrane transporter activity
GO:0046943	8.215e-03	2.528	10 SLC10A2, SLC13A3, SLC16A2, SLC16A4, SLC17A5, SLC25A10, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	carboxylic acid transmembrane transporter activity
GO:0005215	1.013e-02	29.43	49 ABCC2, ABCC8, AP1S3, AQP3, ATP6V0A4, ATP6V0D2, ATP6V0E1, CACNA1C, CLCN5, CLDN16, CUBN, CYB5A, GJB1, HCN4, ITPR2, KCNJ1, KCNJ16, KCNK5, OSTalpha, RHCG, RYR2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC25A10, SLC26A7, SLC2A2, SLC2A9, SLC31A1, SLC34A1, SLC39A9, SLC3A1, SLC40A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SNX2, TRPM6, TRPV4	454	transporter activity
GO:0015293	1.055e-02	3.63	12 SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC2A9, SLC34A1, SLC5A12, SLC5A9, SLC6A19	56	symporter activity
GO:0016831	1.175e-02	0.6482	5 ACMSD, DDC, PCK1, PCK2, SGPL1	10	carboxy-lyase activity
GO:0030170	1.272e-02	1.361	7 AGXT, CTH, DDC, GLDC, SDSL, SGPL1, THNSL2	21	pyridoxal phosphate binding
GO:0070279	1.272e-02	1.361	7 AGXT, CTH, DDC, GLDC, SDSL, SGPL1, THNSL2	21	vitamin B6 binding
GO:0015291	1.380e-02	5.445	15 CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A2, SLC16A4, SLC17A5, SLC22A7, SLC26A7, SLC2A9, SLC34A1, SLC5A12, SLC5A9, SLC6A19	84	secondary active transmembrane transporter activity
GO:0015075	1.816e-02	19.45	35 ABCC2, ABCC8, ATP6V0A4, ATP6V0D2, ATP6V0E1, CACNA1C, CLCN5, CLDN16, CYB5A, HCN4, ITPR2, KCNJ1, KCNJ16, KCNK5, RHCG, RYR2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC17A5, SLC22A7, SLC26A7, SLC2A9, SLC31A1, SLC34A1, SLC39A9, SLC40A1, SLC5A9, SLC6A19, TRPM6, TRPV4	300	ion transmembrane transporter activity
GO:0016614	2.124e-02	1.945	8 AKR1A1, CRYL1, CYB5A, EHHADH, HAO2, HSD11B2, IDH1, LDHD	30	oxidoreductase activity, acting on CH-OH group of donors
GO:0003729	2.784e-02	1.167	6 A1CF, ACO1, ELAVL2, ELAVL4, ESRP1, ESRP2	18	mRNA binding
GO:0046873	3.044e-02	3.63	11 ABCC8, CLDN16, ITPR2, SLC10A2, SLC13A1, SLC13A3, SLC31A1, SLC39A9, SLC40A1, SLC5A9, SLC6A19	56	metal ion transmembrane transporter activity
GO:0016830	3.515e-02	0.8426	5 ACMSD, DDC, PCK1, PCK2, SGPL1	13	carbon-carbon lyase activity
GO:0016903	3.515e-02	0.8426	5 ALDH2, ALDH6A1, ALDH8A1, ALDH9A1, DHTKD1	13	oxidoreductase activity, acting on the aldehyde or oxo group of donors
GO:0016620	3.663e-02	0.5185	4 ALDH2, ALDH6A1, ALDH8A1, ALDH9A1	8	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0008233	3.722e-02	11.54	23 ACE2, ADAM23, APEH, CASP6, CTSH, DPEP1, DPP4, ENPEP, GGH, IHH, LAP3, LGMN, MMP7, PDIA3, PEPD, PGPEP1, SCRN2, ST14, TINAG, TMEM27, TMPRSS2, TPP1, XPNPEP2	178	peptidase activity
GO:0015280	3.764e-02	0.2593	3 SCNN1A, SCNN1B, SCNN1G	4	amiloride-sensitive sodium channel activity
GO:0016805	3.764e-02	0.2593	3 DPEP1, PEPD, SCRN2	4	dipeptidase activity
GO:0070011	4.609e-02	11.08	22 ACE2, ADAM23, APEH, CASP6, CTSH, DPEP1, DPP4, ENPEP, GGH, LAP3, LGMN, MMP7, PDIA3, PEPD, PGPEP1, SCRN2, ST14, TINAG, TMEM27, TMPRSS2, TPP1, XPNPEP2	171	peptidase activity, acting on L-amino acid peptides

Id	Pvalue	ExpCount	Count	Size	Term
01100	1.298e-05	27.89	54 ACMSD, ACO1, ACSM3, ACSM5, ACSS3, AGXT, AK2, AKR1A1, ALDH2, ALDH6A1, ALDH9A1, AMDHD1, ARSB, ATP6V0A4, ATP6V0D2, ATP6V0E1, CRYL1, CTH, DAK, DAO, DDC, DHRS3, DMGDH, DPYS, EHHADH, EPHX2, ETNK2, GALK1, GALK2, GATM, GLB1, GLDC, GLYCTK, HAO2, HGD, HSD11B2, HYI, IDH1, IVD, KMO, LAP3, MCCC1, PAFAH2, PAH, PANK1, PCK1, PCK2, PLA2G12B, PLCB4, PLCG2, PPCS, SARDH, SGPL1, UPB1	353	Metabolic pathways
00260	1.742e-04	1.027	8 AGXT, CTH, DAO, DMGDH, GATM, GLDC, GLYCTK, SARDH	13	Glycine, serine and threonine metabolism
00410	1.500e-02	0.7111	5 ALDH2, ALDH9A1, DPYS, EHHADH, UPB1	9	beta-Alanine metabolism
00770	2.263e-02	0.4741	4 DPYS, PANK1, PPCS, UPB1	6	Pantothenate and CoA biosynthesis
00640	2.354e-02	0.7901	5 ACSS3, ALDH2, ALDH6A1, ALDH9A1, EHHADH	10	Propanoate metabolism
00620	2.610e-02	1.185	6 ACOT12, ALDH2, ALDH9A1, LDHD, PCK1, PCK2	15	Pyruvate metabolism
00380	3.472e-02	1.264	6 ACMSD, ALDH2, ALDH9A1, DDC, EHHADH, KMO	16	Tryptophan metabolism
00280	4.555e-02	1.343	6 ALDH2, ALDH6A1, ALDH9A1, EHHADH, IVD, MCCC1	17	Valine, leucine and isoleucine degradation
00010	4.831e-02	0.9481	5 AKR1A1, ALDH2, ALDH9A1, PCK1, PCK2	12	Glycolysis / Gluconeogenesis
04142	4.991e-02	4.03	11 AP1S3, ARSB, ATP6V0A4, ATP6V0D2, CLN5, CTSH, GLB1, LGMN, SLC17A5, SUMF1, TPP1	51	Lysosome

No enriched terms

No enriched terms

Entrez genes

A1CFAPOBEC1 complementation factor (ENSG00000148584), score: 0.84 A2BP1ataxin 2-binding protein 1 (ENSG00000078328), score: -0.72 ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ENSG00000023839), score: 0.86 ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (ENSG00000006071), score: -0.65 ACE2angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ENSG00000130234), score: 0.71 ACMSDaminocarboxymuconate semialdehyde decarboxylase (ENSG00000153086), score: 1 ACO1aconitase 1, soluble (ENSG00000122729), score: 0.85 ACOT12acyl-CoA thioesterase 12 (ENSG00000172497), score: 0.69 ACSM3acyl-CoA synthetase medium-chain family member 3 (ENSG00000005187), score: 0.82 ACSM5acyl-CoA synthetase medium-chain family member 5 (ENSG00000183549), score: 0.7 ACSS3acyl-CoA synthetase short-chain family member 3 (ENSG00000111058), score: 0.72 ADAM23ADAM metallopeptidase domain 23 (ENSG00000114948), score: -0.75 AFF1AF4/FMR2 family, member 1 (ENSG00000172493), score: 0.64 AGPHD1aminoglycoside phosphotransferase domain containing 1 (ENSG00000188266), score: 0.82 AGR2anterior gradient homolog 2 (Xenopus laevis) (ENSG00000106541), score: 0.69 AGXTalanine-glyoxylate aminotransferase (ENSG00000172482), score: 0.67 AIM1absent in melanoma 1 (ENSG00000112297), score: 0.71 AK2adenylate kinase 2 (ENSG00000004455), score: 0.68 AKAP6A kinase (PRKA) anchor protein 6 (ENSG00000151320), score: -0.75 AKR1A1aldo-keto reductase family 1, member A1 (aldehyde reductase) (ENSG00000117448), score: 0.83 ALDH2aldehyde dehydrogenase 2 family (mitochondrial) (ENSG00000111275), score: 0.71 ALDH6A1aldehyde dehydrogenase 6 family, member A1 (ENSG00000119711), score: 0.77 ALDH8A1aldehyde dehydrogenase 8 family, member A1 (ENSG00000118514), score: 0.89 ALDH9A1aldehyde dehydrogenase 9 family, member A1 (ENSG00000143149), score: 0.7 AMDHD1amidohydrolase domain containing 1 (ENSG00000139344), score: 0.65 ANKS4Bankyrin repeat and sterile alpha motif domain containing 4B (ENSG00000175311), score: 0.95 AP1S3adaptor-related protein complex 1, sigma 3 subunit (ENSG00000152056), score: 0.67 APEHN-acylaminoacyl-peptide hydrolase (ENSG00000164062), score: 0.7 AQP3aquaporin 3 (Gill blood group) (ENSG00000165272), score: 0.7 ARHGAP26Rho GTPase activating protein 26 (ENSG00000145819), score: -0.65 ARHGEF38Rho guanine nucleotide exchange factor (GEF) 38 (ENSG00000138784), score: 0.63 ARSBarylsulfatase B (ENSG00000113273), score: 0.64 ATL1atlastin GTPase 1 (ENSG00000198513), score: -0.64 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.82 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.78 ATP6V0E1ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 (ENSG00000113732), score: 0.68 AVPR1Aarginine vasopressin receptor 1A (ENSG00000166148), score: 0.69 BBOX1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (ENSG00000129151), score: 0.76 BPHLbiphenyl hydrolase-like (serine hydrolase) (ENSG00000137274), score: 0.81 BTRCbeta-transducin repeat containing (ENSG00000166167), score: -0.67 C11orf54chromosome 11 open reading frame 54 (ENSG00000182919), score: 0.92 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.66 C1orf183chromosome 1 open reading frame 183 (ENSG00000197852), score: -0.64 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.77 CA12carbonic anhydrase XII (ENSG00000074410), score: 0.73 CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunit (ENSG00000151067), score: -0.66 CALML4calmodulin-like 4 (ENSG00000129007), score: 0.72 CAMK2Acalcium/calmodulin-dependent protein kinase II alpha (ENSG00000070808), score: -0.64 CAMSAP1calmodulin regulated spectrin-associated protein 1 (ENSG00000130559), score: -0.78 CAMSAP1L1calmodulin regulated spectrin-associated protein 1-like 1 (ENSG00000118200), score: -0.65 CASP6caspase 6, apoptosis-related cysteine peptidase (ENSG00000138794), score: 0.64 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.83 CCDC88Acoiled-coil domain containing 88A (ENSG00000115355), score: -0.66 CDCP1CUB domain containing protein 1 (ENSG00000163814), score: 0.66 CDH1cadherin 1, type 1, E-cadherin (epithelial) (ENSG00000039068), score: 0.93 CELF2CUGBP, Elav-like family member 2 (ENSG00000048740), score: -0.75 CHN1chimerin (chimaerin) 1 (ENSG00000128656), score: -0.68 CISHcytokine inducible SH2-containing protein (ENSG00000114737), score: 0.66 CKAP5cytoskeleton associated protein 5 (ENSG00000175216), score: -0.73 CLCN5chloride channel 5 (ENSG00000171365), score: 0.81 CLDN1claudin 1 (ENSG00000163347), score: 0.77 CLDN16claudin 16 (ENSG00000113946), score: 0.87 CLDN19claudin 19 (ENSG00000164007), score: 0.72 CLINT1clathrin interactor 1 (ENSG00000113282), score: 0.71 CLN5ceroid-lipofuscinosis, neuronal 5 (ENSG00000102805), score: 0.71 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.71 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.67 CRYL1crystallin, lambda 1 (ENSG00000165475), score: 0.85 CTBSchitobiase, di-N-acetyl- (ENSG00000117151), score: 0.64 CTDSPLCTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like (ENSG00000144677), score: 0.64 CTHcystathionase (cystathionine gamma-lyase) (ENSG00000116761), score: 0.71 CTNND1catenin (cadherin-associated protein), delta 1 (ENSG00000198561), score: 0.64 CTNND2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) (ENSG00000169862), score: -0.65 CTSHcathepsin H (ENSG00000103811), score: 0.77 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.84 CYB5Acytochrome b5 type A (microsomal) (ENSG00000166347), score: 0.83 CYBASC3cytochrome b, ascorbate dependent 3 (ENSG00000162144), score: 0.66 CYTIPcytohesin 1 interacting protein (ENSG00000115165), score: 0.69 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.85 DAKdihydroxyacetone kinase 2 homolog (S. cerevisiae) (ENSG00000149476), score: 0.77 DAOD-amino-acid oxidase (ENSG00000110887), score: 0.85 DDCdopa decarboxylase (aromatic L-amino acid decarboxylase) (ENSG00000132437), score: 0.95 DECR22,4-dienoyl CoA reductase 2, peroxisomal (ENSG00000242612), score: 0.7 DENND2DDENN/MADD domain containing 2D (ENSG00000162777), score: 0.82 DHDPSLdihydrodipicolinate synthase-like, mitochondrial (ENSG00000241935), score: 0.96 DHRS3dehydrogenase/reductase (SDR family) member 3 (ENSG00000162496), score: 0.64 DHTKD1dehydrogenase E1 and transketolase domain containing 1 (ENSG00000181192), score: 0.8 DMGDHdimethylglycine dehydrogenase (ENSG00000132837), score: 0.9 DNAJC22DnaJ (Hsp40) homolog, subfamily C, member 22 (ENSG00000178401), score: 0.82 DOCK3dedicator of cytokinesis 3 (ENSG00000088538), score: -0.65 DPEP1dipeptidase 1 (renal) (ENSG00000015413), score: 0.74 DPP4dipeptidyl-peptidase 4 (ENSG00000197635), score: 0.89 DPYSdihydropyrimidinase (ENSG00000147647), score: 0.82 DPYSL4dihydropyrimidinase-like 4 (ENSG00000151640), score: -0.65 DTNAdystrobrevin, alpha (ENSG00000134769), score: -0.71 DUSP26dual specificity phosphatase 26 (putative) (ENSG00000133878), score: -0.64 DYNC1I1dynein, cytoplasmic 1, intermediate chain 1 (ENSG00000158560), score: -0.69 ECHDC3enoyl CoA hydratase domain containing 3 (ENSG00000134463), score: 0.7 EDEM1ER degradation enhancer, mannosidase alpha-like 1 (ENSG00000134109), score: 0.64 EFR3BEFR3 homolog B (S. cerevisiae) (ENSG00000084710), score: -0.68 EGFepidermal growth factor (ENSG00000138798), score: 0.66 EHFets homologous factor (ENSG00000135373), score: 0.84 EHHADHenoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (ENSG00000113790), score: 0.86 ELAVL2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) (ENSG00000107105), score: -0.65 ELAVL4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) (ENSG00000162374), score: -0.64 ELF1E74-like factor 1 (ets domain transcription factor) (ENSG00000120690), score: 0.62 ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ENSG00000163435), score: 0.92 ELF5E74-like factor 5 (ets domain transcription factor) (ENSG00000135374), score: 0.82 ELMO3engulfment and cell motility 3 (ENSG00000102890), score: 0.71 ENPEPglutamyl aminopeptidase (aminopeptidase A) (ENSG00000138792), score: 0.93 EPCAMepithelial cell adhesion molecule (ENSG00000119888), score: 0.81 EPHA1EPH receptor A1 (ENSG00000146904), score: 0.68 EPHX2epoxide hydrolase 2, cytoplasmic (ENSG00000120915), score: 0.77 ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ENSG00000141736), score: 0.76 ERLIN2ER lipid raft associated 2 (ENSG00000147475), score: 0.65 ESR1estrogen receptor 1 (ENSG00000091831), score: 0.72 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.77 ESRP2epithelial splicing regulatory protein 2 (ENSG00000103067), score: 0.82 ETNK2ethanolamine kinase 2 (ENSG00000143845), score: 0.67 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.89 FAM110Cfamily with sequence similarity 110, member C (ENSG00000184731), score: 0.77 FAM167Bfamily with sequence similarity 167, member B (ENSG00000183615), score: 0.75 FAM176Afamily with sequence similarity 176, member A (ENSG00000115363), score: 0.76 FAM83Hfamily with sequence similarity 83, member H (ENSG00000180921), score: 0.79 FBXW7F-box and WD repeat domain containing 7 (ENSG00000109670), score: -0.81 FGFR4fibroblast growth factor receptor 4 (ENSG00000160867), score: 0.9 FOXI1forkhead box I1 (ENSG00000168269), score: 0.88 FZD4frizzled homolog 4 (Drosophila) (ENSG00000174804), score: 0.65 FZD5frizzled homolog 5 (Drosophila) (ENSG00000163251), score: 0.72 GALK1galactokinase 1 (ENSG00000108479), score: 0.75 GALK2galactokinase 2 (ENSG00000156958), score: 0.77 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.89 GATMglycine amidinotransferase (L-arginine:glycine amidinotransferase) (ENSG00000171766), score: 0.63 GGHgamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (ENSG00000137563), score: 0.68 GJB1gap junction protein, beta 1, 32kDa (ENSG00000169562), score: 0.69 GLB1galactosidase, beta 1 (ENSG00000170266), score: 0.71 GLDCglycine dehydrogenase (decarboxylating) (ENSG00000178445), score: 0.82 GLYCTKglycerate kinase (ENSG00000168237), score: 0.87 GPM6Bglycoprotein M6B (ENSG00000046653), score: -0.67 GPR160G protein-coupled receptor 160 (ENSG00000173890), score: 0.64 GPRC5CG protein-coupled receptor, family C, group 5, member C (ENSG00000170412), score: 0.78 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.79 HAO2hydroxyacid oxidase 2 (long chain) (ENSG00000116882), score: 0.99 HCN4hyperpolarization activated cyclic nucleotide-gated potassium channel 4 (ENSG00000138622), score: -0.65 HDAC9histone deacetylase 9 (ENSG00000048052), score: -0.72 HGDhomogentisate 1,2-dioxygenase (ENSG00000113924), score: 0.91 HNF1AHNF1 homeobox A (ENSG00000135100), score: 0.94 HNF4Ahepatocyte nuclear factor 4, alpha (ENSG00000101076), score: 0.96 HNF4Ghepatocyte nuclear factor 4, gamma (ENSG00000164749), score: 0.89 HOXA10homeobox A10 (ENSG00000153807), score: 0.88 HOXB7homeobox B7 (ENSG00000120087), score: 0.88 HOXD10homeobox D10 (ENSG00000128710), score: 0.84 HOXD4homeobox D4 (ENSG00000170166), score: 0.81 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.93 HYIhydroxypyruvate isomerase (putative) (ENSG00000178922), score: 0.63 IDH1isocitrate dehydrogenase 1 (NADP+), soluble (ENSG00000138413), score: 0.78 IGFBP3insulin-like growth factor binding protein 3 (ENSG00000146674), score: 0.62 IGFBP7insulin-like growth factor binding protein 7 (ENSG00000163453), score: 0.65 IHHIndian hedgehog (ENSG00000163501), score: 0.77 IL13RA1interleukin 13 receptor, alpha 1 (ENSG00000131724), score: 0.65 IL22RA1interleukin 22 receptor, alpha 1 (ENSG00000142677), score: 0.74 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.83 IRF6interferon regulatory factor 6 (ENSG00000117595), score: 0.8 ITGA1integrin, alpha 1 (ENSG00000213949), score: 0.66 ITPR2inositol 1,4,5-triphosphate receptor, type 2 (ENSG00000123104), score: 0.65 IVDisovaleryl-CoA dehydrogenase (ENSG00000128928), score: 0.65 IYDiodotyrosine deiodinase (ENSG00000009765), score: 0.85 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.88 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.67 KCNK5potassium channel, subfamily K, member 5 (ENSG00000164626), score: 1 KIAA1522KIAA1522 (ENSG00000162522), score: 0.64 KIF12kinesin family member 12 (ENSG00000136883), score: 0.84 KIF13Bkinesin family member 13B (ENSG00000197892), score: 0.63 KIF3Akinesin family member 3A (ENSG00000131437), score: -0.68 KIF5Ckinesin family member 5C (ENSG00000168280), score: -0.64 KLklotho (ENSG00000133116), score: 0.77 KLHDC7Akelch domain containing 7A (ENSG00000179023), score: 0.86 KLHL14kelch-like 14 (Drosophila) (ENSG00000197705), score: 0.63 KLHL23kelch-like 23 (Drosophila) (ENSG00000213160), score: -0.67 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (ENSG00000117009), score: 0.83 LAD1ladinin 1 (ENSG00000159166), score: 0.91 LAP3leucine aminopeptidase 3 (ENSG00000002549), score: 0.62 LDHDlactate dehydrogenase D (ENSG00000166816), score: 0.64 LGALS2lectin, galactoside-binding, soluble, 2 (ENSG00000100079), score: 0.78 LGMNlegumain (ENSG00000100600), score: 0.85 LGR4leucine-rich repeat-containing G protein-coupled receptor 4 (ENSG00000205213), score: 0.79 LLGL2lethal giant larvae homolog 2 (Drosophila) (ENSG00000073350), score: 0.85 LMX1BLIM homeobox transcription factor 1, beta (ENSG00000136944), score: 0.66 LPCAT3lysophosphatidylcholine acyltransferase 3 (ENSG00000111684), score: 0.65 LRP8low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (ENSG00000157193), score: -0.66 MAP1Bmicrotubule-associated protein 1B (ENSG00000131711), score: -0.65 MARK1MAP/microtubule affinity-regulating kinase 1 (ENSG00000116141), score: -0.68 MARVELD2MARVEL domain containing 2 (ENSG00000152939), score: 0.79 MARVELD3MARVEL domain containing 3 (ENSG00000140832), score: 0.96 MCCC1methylcrotonoyl-CoA carboxylase 1 (alpha) (ENSG00000078070), score: 0.63 MMP7matrix metallopeptidase 7 (matrilysin, uterine) (ENSG00000137673), score: 0.69 MPZL2myelin protein zero-like 2 (ENSG00000149573), score: 0.77 MSRAmethionine sulfoxide reductase A (ENSG00000175806), score: 0.73 MYH9myosin, heavy chain 9, non-muscle (ENSG00000100345), score: 0.64 MYO1Dmyosin ID (ENSG00000176658), score: 0.65 NAPRT1nicotinate phosphoribosyltransferase domain containing 1 (ENSG00000147813), score: 0.66 NDRG4NDRG family member 4 (ENSG00000103034), score: -0.8 NIPSNAP1nipsnap homolog 1 (C. elegans) (ENSG00000184117), score: 0.66 NIT2nitrilase family, member 2 (ENSG00000114021), score: 0.77 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.77 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 0.84 NPNTnephronectin (ENSG00000168743), score: 0.7 NPR3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (ENSG00000113389), score: 0.63 NR1H4nuclear receptor subfamily 1, group H, member 4 (ENSG00000012504), score: 0.83 NTMneurotrimin (ENSG00000182667), score: -0.64 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.81 OSTalphaorganic solute transporter alpha (ENSG00000163959), score: 0.79 PAFAH2platelet-activating factor acetylhydrolase 2, 40kDa (ENSG00000158006), score: 0.73 PAHphenylalanine hydroxylase (ENSG00000171759), score: 0.82 PANK1pantothenate kinase 1 (ENSG00000152782), score: 0.64 PAWRPRKC, apoptosis, WT1, regulator (ENSG00000177425), score: 0.66 PCK1phosphoenolpyruvate carboxykinase 1 (soluble) (ENSG00000124253), score: 0.9 PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial) (ENSG00000100889), score: 0.86 PDIA3protein disulfide isomerase family A, member 3 (ENSG00000167004), score: 0.65 PDS5BPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) (ENSG00000083642), score: -0.64 PEPDpeptidase D (ENSG00000124299), score: 0.94 PGPEP1pyroglutamyl-peptidase I (ENSG00000130517), score: 0.79 PLA2G12Bphospholipase A2, group XIIB (ENSG00000138308), score: 0.72 PLCB4phospholipase C, beta 4 (ENSG00000101333), score: -0.64 PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific) (ENSG00000197943), score: 0.87 PLCXD2phosphatidylinositol-specific phospholipase C, X domain containing 2 (ENSG00000144824), score: 0.64 PLP1proteolipid protein 1 (ENSG00000123560), score: -0.71 PLS1plastin 1 (ENSG00000120756), score: 0.81 POFUT1protein O-fucosyltransferase 1 (ENSG00000101346), score: 0.64 PPCSphosphopantothenoylcysteine synthetase (ENSG00000127125), score: 0.67 PPIBpeptidylprolyl isomerase B (cyclophilin B) (ENSG00000166794), score: 0.67 PROM2prominin 2 (ENSG00000155066), score: 0.73 PRRG4proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) (ENSG00000135378), score: 0.8 PTPN6protein tyrosine phosphatase, non-receptor type 6 (ENSG00000111679), score: 0.8 PYROXD2pyridine nucleotide-disulphide oxidoreductase domain 2 (ENSG00000119943), score: 0.65 RAB17RAB17, member RAS oncogene family (ENSG00000124839), score: 0.94 RAB19RAB19, member RAS oncogene family (ENSG00000146955), score: 0.63 RAB20RAB20, member RAS oncogene family (ENSG00000139832), score: 0.67 RAB7L1RAB7, member RAS oncogene family-like 1 (ENSG00000117280), score: 0.72 RAB9BRAB9B, member RAS oncogene family (ENSG00000123570), score: -0.64 RADILRas association and DIL domains (ENSG00000157927), score: -0.73 RASSF6Ras association (RalGDS/AF-6) domain family member 6 (ENSG00000169435), score: 0.75 RBKSribokinase (ENSG00000171174), score: 0.83 REEP1receptor accessory protein 1 (ENSG00000068615), score: -0.82 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.76 RIPK4receptor-interacting serine-threonine kinase 4 (ENSG00000183421), score: 0.89 RNF152ring finger protein 152 (ENSG00000176641), score: 0.67 RRBP1ribosome binding protein 1 homolog 180kDa (dog) (ENSG00000125844), score: 0.64 RUNX1T1runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (ENSG00000079102), score: -0.67 RYR2ryanodine receptor 2 (cardiac) (ENSG00000198626), score: -0.68 SACSspastic ataxia of Charlevoix-Saguenay (sacsin) (ENSG00000151835), score: -0.8 SALL1sal-like 1 (Drosophila) (ENSG00000103449), score: 0.77 SAMD8sterile alpha motif domain containing 8 (ENSG00000156671), score: -0.69 SARDHsarcosine dehydrogenase (ENSG00000123453), score: 0.84 SCAMP2secretory carrier membrane protein 2 (ENSG00000140497), score: 0.71 SCINscinderin (ENSG00000006747), score: 0.7 SCNN1Asodium channel, nonvoltage-gated 1 alpha (ENSG00000111319), score: 0.87 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.77 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.73 SCRN2secernin 2 (ENSG00000141295), score: 0.76 SDSLserine dehydratase-like (ENSG00000139410), score: 0.67 SERPINF2serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (ENSG00000167711), score: 0.74 SFXN2sideroflexin 2 (ENSG00000156398), score: 0.85 SGK2serum/glucocorticoid regulated kinase 2 (ENSG00000101049), score: 0.85 SGPL1sphingosine-1-phosphate lyase 1 (ENSG00000166224), score: 0.66 SH2D4ASH2 domain containing 4A (ENSG00000104611), score: 0.8 SH3GL3SH3-domain GRB2-like 3 (ENSG00000140600), score: -0.64 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.83 SIM2single-minded homolog 2 (Drosophila) (ENSG00000159263), score: 0.68 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.74 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.88 SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (ENSG00000158296), score: 0.82 SLC16A12solute carrier family 16, member 12 (monocarboxylic acid transporter 12) (ENSG00000152779), score: 0.87 SLC16A2solute carrier family 16, member 2 (monocarboxylic acid transporter 8) (ENSG00000147100), score: 0.76 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.89 SLC17A5solute carrier family 17 (anion/sugar transporter), member 5 (ENSG00000119899), score: 0.64 SLC22A7solute carrier family 22 (organic anion transporter), member 7 (ENSG00000137204), score: 0.96 SLC25A10solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 (ENSG00000183048), score: 0.93 SLC26A7solute carrier family 26, member 7 (ENSG00000147606), score: 0.66 SLC2A2solute carrier family 2 (facilitated glucose transporter), member 2 (ENSG00000163581), score: 0.82 SLC2A9solute carrier family 2 (facilitated glucose transporter), member 9 (ENSG00000109667), score: 0.79 SLC31A1solute carrier family 31 (copper transporters), member 1 (ENSG00000136868), score: 0.66 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.91 SLC38A10solute carrier family 38, member 10 (ENSG00000157637), score: 0.64 SLC39A9solute carrier family 39 (zinc transporter), member 9 (ENSG00000029364), score: 0.7 SLC3A1solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 (ENSG00000138079), score: 0.63 SLC40A1solute carrier family 40 (iron-regulated transporter), member 1 (ENSG00000138449), score: 0.69 SLC45A3solute carrier family 45, member 3 (ENSG00000158715), score: 0.66 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.89 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 1 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.91 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.92 SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (ENSG00000109062), score: 0.81 SNX2sorting nexin 2 (ENSG00000205302), score: 0.64 SOX8SRY (sex determining region Y)-box 8 (ENSG00000005513), score: -0.66 SPG21spastic paraplegia 21 (autosomal recessive, Mast syndrome) (ENSG00000090487), score: 0.64 SPTBspectrin, beta, erythrocytic (ENSG00000070182), score: -0.69 ST14suppression of tumorigenicity 14 (colon carcinoma) (ENSG00000149418), score: 0.86 SUMF1sulfatase modifying factor 1 (ENSG00000144455), score: 0.81 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.69 SUSD3sushi domain containing 3 (ENSG00000157303), score: 0.64 TBX2T-box 2 (ENSG00000121068), score: 0.76 TCF21transcription factor 21 (ENSG00000118526), score: 0.7 TCN2transcobalamin II (ENSG00000185339), score: 0.79 TDRKHtudor and KH domain containing (ENSG00000182134), score: -0.66 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.85 THBS1thrombospondin 1 (ENSG00000137801), score: 0.68 THNSL2threonine synthase-like 2 (S. cerevisiae) (ENSG00000144115), score: 0.74 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.88 TJP3tight junction protein 3 (zona occludens 3) (ENSG00000105289), score: 0.63 TM6SF1transmembrane 6 superfamily member 1 (ENSG00000136404), score: -0.69 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.72 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.98 TMEM82transmembrane protein 82 (ENSG00000162460), score: 0.79 TMIGD1transmembrane and immunoglobulin domain containing 1 (ENSG00000182271), score: 0.76 TMPRSS2transmembrane protease, serine 2 (ENSG00000184012), score: 0.97 TNFSF10tumor necrosis factor (ligand) superfamily, member 10 (ENSG00000121858), score: 0.72 TNFSF15tumor necrosis factor (ligand) superfamily, member 15 (ENSG00000181634), score: 0.66 TNRC6Ctrinucleotide repeat containing 6C (ENSG00000078687), score: -0.66 TPMTthiopurine S-methyltransferase (ENSG00000137364), score: 0.68 TPP1tripeptidyl peptidase I (ENSG00000166340), score: 0.68 TRIB1tribbles homolog 1 (Drosophila) (ENSG00000173334), score: 0.63 TRPM6transient receptor potential cation channel, subfamily M, member 6 (ENSG00000119121), score: 0.7 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.89 TSKUtsukushi small leucine rich proteoglycan homolog (Xenopus laevis) (ENSG00000182704), score: 0.75 TTC36tetratricopeptide repeat domain 36 (ENSG00000172425), score: 0.8 TTLL7tubulin tyrosine ligase-like family, member 7 (ENSG00000137941), score: -0.74 UPB1ureidopropionase, beta (ENSG00000100024), score: 0.87 WDR72WD repeat domain 72 (ENSG00000166415), score: 0.94 XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (ENSG00000122121), score: 0.85 ZEB1zinc finger E-box binding homeobox 1 (ENSG00000148516), score: -0.74 ZFPM2zinc finger protein, multitype 2 (ENSG00000169946), score: -0.78 ZNF536zinc finger protein 536 (ENSG00000198597), score: -0.67

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
oan_lv_f_ca1	oan	lv	f	_
ppa_lv_m_ca1	ppa	lv	m	_
ggo_lv_f_ca1	ggo	lv	f	_
mdo_lv_m_ca1	mdo	lv	m	_
ppy_lv_m_ca1	ppy	lv	m	_
mdo_lv_f_ca1	mdo	lv	f	_
ppa_lv_f_ca1	ppa	lv	f	_
oan_lv_m_ca1	oan	lv	m	_
ptr_lv_m_ca1	ptr	lv	m	_
hsa_lv_m2_ca1	hsa	lv	m	2
gga_lv_m_ca1	gga	lv	m	_
mml_lv_f_ca1	mml	lv	f	_
hsa_lv_m1_ca1	hsa	lv	m	1
ptr_kd_f_ca1	ptr	kd	f	_
ppa_kd_m_ca1	ppa	kd	m	_
mml_lv_m_ca1	mml	lv	m	_
ppy_kd_f_ca1	ppy	kd	f	_
oan_kd_m_ca1	oan	kd	m	_
mmu_kd_f_ca1	mmu	kd	f	_
ggo_kd_f_ca1	ggo	kd	f	_
gga_kd_m_ca1	gga	kd	m	_
gga_kd_f_ca1	gga	kd	f	_
ppa_kd_f_ca1	ppa	kd	f	_
ppy_kd_m_ca1	ppy	kd	m	_
mmu_kd_m2_ca1	mmu	kd	m	2
mmu_kd_m1_ca1	mmu	kd	m	1
mml_kd_m_ca1	mml	kd	m	_
ggo_kd_m_ca1	ggo	kd	m	_
mdo_kd_m_ca1	mdo	kd	m	_
ptr_kd_m_ca1	ptr	kd	m	_
oan_kd_f_ca1	oan	kd	f	_
mml_kd_f_ca1	mml	kd	f	_
hsa_kd_f_ca1	hsa	kd	f	_
mdo_kd_f_ca1	mdo	kd	f	_
hsa_kd_m2_ca1	hsa	kd	m	2
hsa_kd_m1_ca1	hsa	kd	m	1