Previous module | Next module Module #85, TG: 2.8, TC: 2.6, 43 probes, 43 Entrez genes, 6 conditions

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Expression data for module #85

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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cytokine production

The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

regulation of cytokine production

Any process that modulates the frequency, rate, or extent of production of a cytokine.

positive regulation of cytokine production

Any process that activates or increases the frequency, rate or extent of production of a cytokine.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

immune system development

The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

leukocyte differentiation

The process whereby a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell or any cell of the myeloid leukocyte or lymphocyte lineages.

regulation of response to biotic stimulus

Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

response to biotic stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

hemopoiesis

The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

interferon-gamma production

The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.

regulation of interferon-gamma production

Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

positive regulation of interferon-gamma production

Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

hemopoietic or lymphoid organ development

The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

positive regulation of multicellular organismal process

Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

NA

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

positive regulation of multicellular organismal process

Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cytokine production

Any process that modulates the frequency, rate, or extent of production of a cytokine.

positive regulation of multicellular organismal process

Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

positive regulation of cytokine production

Any process that activates or increases the frequency, rate or extent of production of a cytokine.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

regulation of response to biotic stimulus

Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.

positive regulation of cytokine production

Any process that activates or increases the frequency, rate or extent of production of a cytokine.

regulation of interferon-gamma production

Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

positive regulation of interferon-gamma production

Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

immune system development

The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

hemopoietic or lymphoid organ development

The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.

leukocyte differentiation

The process whereby a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell or any cell of the myeloid leukocyte or lymphocyte lineages.

positive regulation of interferon-gamma production

Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

Help | Hide | Top The GO tree — Cellular Components

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Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
05330 7.963e-04 0.04825 3
5 Allograft rejection
04672 1.392e-02 0.1351 3
14 Intestinal immune network for IgA production
04660 1.930e-02 0.3764 4
39 T cell receptor signaling pathway
04940 4.529e-02 0.0579 2
6 Type I diabetes mellitus

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACAD9acyl-CoA dehydrogenase family, member 9 (ENSG00000177646), score: 0.66 APBB3amyloid beta (A4) precursor protein-binding, family B, member 3 (ENSG00000113108), score: -0.77 C13orf39chromosome 13 open reading frame 39 (ENSG00000139780), score: 0.73 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.68 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.61 CA6carbonic anhydrase VI (ENSG00000131686), score: 0.71 CD28CD28 molecule (ENSG00000178562), score: 0.66 CD40LGCD40 ligand (ENSG00000102245), score: 0.77 CDCP2CUB domain containing protein 2 (ENSG00000157211), score: 1 CHRNA5cholinergic receptor, nicotinic, alpha 5 (ENSG00000169684), score: 0.62 DHX32DEAH (Asp-Glu-Ala-His) box polypeptide 32 (ENSG00000089876), score: -0.63 EREGepiregulin (ENSG00000124882), score: 0.69 FAM109Bfamily with sequence similarity 109, member B (ENSG00000177096), score: 0.69 FBXL18F-box and leucine-rich repeat protein 18 (ENSG00000155034), score: 0.71 HPGDShematopoietic prostaglandin D synthase (ENSG00000163106), score: 0.95 ICOSinducible T-cell co-stimulator (ENSG00000163600), score: 0.7 IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (ENSG00000113302), score: 0.78 IL22RA2interleukin 22 receptor, alpha 2 (ENSG00000164485), score: 0.75 IRF8interferon regulatory factor 8 (ENSG00000140968), score: 0.63 LAPTM4Blysosomal protein transmembrane 4 beta (ENSG00000104341), score: -0.61 LASS6LAG1 homolog, ceramide synthase 6 (ENSG00000172292), score: -0.64 LHX8LIM homeobox 8 (ENSG00000162624), score: 0.71 OLFML2Aolfactomedin-like 2A (ENSG00000185585), score: 0.6 ORC5Lorigin recognition complex, subunit 5-like (yeast) (ENSG00000164815), score: -0.63 PANX3pannexin 3 (ENSG00000154143), score: 0.69 PAPOLGpoly(A) polymerase gamma (ENSG00000115421), score: -0.66 PATZ1POZ (BTB) and AT hook containing zinc finger 1 (ENSG00000100105), score: -0.66 PDX1pancreatic and duodenal homeobox 1 (ENSG00000139515), score: 0.67 PIK3CGphosphoinositide-3-kinase, catalytic, gamma polypeptide (ENSG00000105851), score: 0.64 RHAGRh-associated glycoprotein (ENSG00000112077), score: 0.64 RPIAribose 5-phosphate isomerase A (ENSG00000153574), score: 0.7 SEPT2septin 2 (ENSG00000168385), score: -0.62 SLBPstem-loop binding protein (ENSG00000163950), score: -0.63 SLC26A5solute carrier family 26, member 5 (prestin) (ENSG00000170615), score: 0.84 SPINK4serine peptidase inhibitor, Kazal type 4 (ENSG00000122711), score: 0.85 TAF3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa (ENSG00000165632), score: 0.63 TM7SF4transmembrane 7 superfamily member 4 (ENSG00000164935), score: 0.61 TMPRSS13transmembrane protease, serine 13 (ENSG00000137747), score: 0.65 TMX1thioredoxin-related transmembrane protein 1 (ENSG00000139921), score: -0.61 TNFRSF11Atumor necrosis factor receptor superfamily, member 11a, NFKB activator (ENSG00000141655), score: 0.69 WDR41WD repeat domain 41 (ENSG00000164253), score: -0.77 ZBTB8Bzinc finger and BTB domain containing 8B (ENSG00000215897), score: 0.64 ZNF704zinc finger protein 704 (ENSG00000164684), score: 0.63

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id species tissue sex individual
gga_ht_f_ca1 gga ht f _
gga_ht_m_ca1 gga ht m _
gga_kd_f_ca1 gga kd f _
gga_kd_m_ca1 gga kd m _
gga_lv_f_ca1 gga lv f _
gga_lv_m_ca1 gga lv m _

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