http://www2.unil.ch/cbg/index.php?title=Bias_in_de_novo_germline_mutation_rates&feed=atom&action=history
Bias in de novo germline mutation rates - Revision history
2024-03-29T14:23:41Z
Revision history for this page on the wiki
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http://www2.unil.ch/cbg/index.php?title=Bias_in_de_novo_germline_mutation_rates&diff=4798&oldid=prev
WikiSysop at 08:23, 6 June 2016
2016-06-06T08:23:51Z
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 08:23, 6 June 2016</td>
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<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Le rapport <del class="diffchange diffchange-inline">est </del>[[File:Bias_in_de_novo_germline_mutation_rates.pdf ]]</div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Le rapport<ins class="diffchange diffchange-inline">: </ins>[[File:Bias_in_de_novo_germline_mutation_rates.pdf ]]</div></td></tr>
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WikiSysop
http://www2.unil.ch/cbg/index.php?title=Bias_in_de_novo_germline_mutation_rates&diff=4797&oldid=prev
WikiSysop at 08:22, 6 June 2016
2016-06-06T08:22:33Z
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 08:22, 6 June 2016</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Supervisor''': [[ User:Micha | Micha]]</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Supervisor''': [[ User:Micha | Micha]]</div></td></tr>
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WikiSysop
http://www2.unil.ch/cbg/index.php?title=Bias_in_de_novo_germline_mutation_rates&diff=4668&oldid=prev
Micha at 15:07, 17 February 2016
2016-02-17T15:07:42Z
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 15:07, 17 February 2016</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Biological aspects''': The biology of germline mutations and their consequence in terms of population genetics.</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Biological aspects''': The biology of germline mutations and their consequence in terms of population genetics.</div></td></tr>
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<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''Supervisor''': [ User:Micha | Micha]</div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''Supervisor''': <ins class="diffchange diffchange-inline">[</ins>[ User:Micha | Micha<ins class="diffchange diffchange-inline">]</ins>]</div></td></tr>
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Micha
http://www2.unil.ch/cbg/index.php?title=Bias_in_de_novo_germline_mutation_rates&diff=4667&oldid=prev
Micha at 15:07, 17 February 2016
2016-02-17T15:07:24Z
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 15:07, 17 February 2016</td>
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<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''Background''': A crucial aspect of evolution and a key component of <del class="diffchange diffchange-inline">its </del>creativity <del class="diffchange diffchange-inline">is </del>the  </div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''Background''': A crucial aspect of evolution and a key component of <ins class="diffchange diffchange-inline">the </ins>creativity <ins class="diffchange diffchange-inline">displayed by the evolutionary process lies in the so called de novo, or spontaneous, mutations. These are new random mutations that usually originate in the germlines and sporadically appear in an individual of a population. Depending on whether this mutation confers an evolutionary advantage or dis-advantage, it will spread or not in the population. When disadvantageous, these mutation can also cause diseases. Biases in the novo mutation rates may have far reaching implications for dynamics of the evolutionary process and </ins>the <ins class="diffchange diffchange-inline">health of a population. </ins></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Goal''': The goal of this project is to identify the presence of biases affecting de novo germline mutations. In other words, the students will try to identify what are the factors influencing the probability of spontaneous mutations. We will focus on single nucleotide mutations.</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Goal''': The goal of this project is to identify the presence of biases affecting de novo germline mutations. In other words, the students will try to identify what are the factors influencing the probability of spontaneous mutations. We will focus on single nucleotide mutations.</div></td></tr>
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Micha
http://www2.unil.ch/cbg/index.php?title=Bias_in_de_novo_germline_mutation_rates&diff=4666&oldid=prev
Micha at 14:57, 17 February 2016
2016-02-17T14:57:37Z
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<p><b>New page</b></p><div>'''Background''': A crucial aspect of evolution and a key component of its creativity is the <br />
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'''Goal''': The goal of this project is to identify the presence of biases affecting de novo germline mutations. In other words, the students will try to identify what are the factors influencing the probability of spontaneous mutations. We will focus on single nucleotide mutations.<br />
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'''Mathematical tools''': Statistics, linear regression, mixed models<br />
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'''Biological aspects''': The biology of germline mutations and their consequence in terms of population genetics.<br />
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'''Supervisor''': [ User:Micha | Micha]</div>
Micha