Difference between revisions of "Gene Expression Signatures 101 - The PAM50 gene expression signature"

 
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Revision as of 09:51, 19 November 2018

  • Title: "Gene Expression Signatures 101 - The PAM50 gene expression signature"
  • Papers to be examined:

Perou, C. M. et al. (2000) Molecular portraits of human breast tumours. Nature, 406(6797), 747–752. Parker, J. S. et al. (2009) Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes. Journal of Clinical Oncology, 27(8), 1160–1167. Gatza, M. L. et al. (2014) An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer. Nature Genetics, 46(10), 1051–1059

  • Data and Code:
  • Key bioinformatics concept of this module: "What are gene expression signatures. How are they created and used."