Usual name: Alex
Premier Assistant / Postdoctoral Researcher
- email: adam.smith at unil.ch
- ACM lab web page: https://wwwfbm.unil.ch/physiol/marques_pres_en.html
Alex was trained as a French engineer with a specialisation in Applied Statistics in Rennes. He obtained a CEA PhD scholarship to work on metabolic networks and prokaryote comparative genomics, devising a method to search for candidate genes for sequence-orphan enzymatic activities & integrating evolutionary relationships to inform a high-throughput exploration of the enzymatic activities of a newly-discovered protein family. He then followed his wife to New Zealand, where he worked as a biostatistics post-doc for the Sleep/Wake Research Center, before being recruited by the Malaghan Institute of Medical Research to initiate a bioinformatics workforce there, with as a main project the analysis of RNA-seq data from mouse dendritic cells stimulated with parasite material.
Now back in Europe with his lovely wife, Alex is working on the design and analysis of bulk RNA-seq data generated from staged mESCs in an effort to identify lncRNAs involved in driving or maintaining the cell cycle, as well as exploring publicly-available single-cell data of staged mESCs to establish whether cell-cycle-involved lncRNAs can be identified at the single-cell level.
Alex loves to tinker in R and gnaws at datasets until he can get everything out of them, and enjoys helping out biologists with their experimental designs and statistical analyses – albeit with a lot of frowning.