Narcolepsy
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We are involved in a Genome-wide Association Study on narcolepsy conducted by Mehdi Tafti's Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in Nature Genetics.
Andreas Lüscher, Gábor Csárdi, Aitana Morton de Lachapelle, Zoltán Kutalik, Bastian Peter, Sven Bergmann
ExpressionView--an interactive viewer for modules identified in gene expression data.
Bioinformatics: 2010, 26(16);2062-3
[PubMed:20671149]
[WorldCat.org]
[DOI]