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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

signal transduction

The process whereby an activated receptor conveys information down the signaling pathway, resulting in a change in the function or state of a cell.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

potassium ion transport

The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

homophilic cell adhesion

The attachment of an adhesion molecule in one cell to an identical molecule in an adjacent cell.

cell surface receptor linked signaling pathway

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

G-protein coupled receptor protein signaling pathway

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

G-protein signaling, coupled to cyclic nucleotide second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.

activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.

activation of phospholipase C activity

The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

serotonin receptor signaling pathway

The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

synaptic transmission

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

behavior

The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of phospholipase activity

Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.

positive regulation of phospholipase activity

Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.

positive regulation of phospholipase C activity

Any process that increases the rate of phospholipase C activity.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

cell-cell adhesion

The attachment of one cell to another cell via adhesion molecules.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

second-messenger-mediated signaling

A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell.

cyclic-nucleotide-mediated signaling

A series of molecular signals in which a cell uses a cyclic nucleotide to convert an extracellular signal into a response.

phosphoinositide-mediated signaling

A series of molecular signals in which a cell uses a phosphoinositide to convert an extracellular signal into a response.

biological adhesion

The attachment of a cell or organism to a substrate or other organism.

signaling pathway

The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms.

intracellular signaling pathway

The series of molecular events whereby information is sent from one location to another within a cell.

signaling process

Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.

signaling

The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.

signal transmission

The process whereby a signal is released and/or conveyed from one location to another.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

intracellular signal transduction

The process whereby a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

positive regulation of catalytic activity

Any process that activates or increases the activity of an enzyme.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

positive regulation of molecular function

Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of catalytic activity

Any process that modulates the activity of an enzyme.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of hydrolase activity

Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

positive regulation of hydrolase activity

Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.

regulation of lipase activity

Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.

positive regulation of lipase activity

Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of molecular function

Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.

all

NA

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

signaling process

Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

signal transduction

The process whereby an activated receptor conveys information down the signaling pathway, resulting in a change in the function or state of a cell.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

regulation of catalytic activity

Any process that modulates the activity of an enzyme.

synaptic transmission

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

intracellular signal transduction

The process whereby a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

positive regulation of catalytic activity

Any process that activates or increases the activity of an enzyme.

positive regulation of hydrolase activity

Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.

positive regulation of lipase activity

Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.

potassium ion transport

The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

positive regulation of phospholipase activity

Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.

G-protein signaling, coupled to cyclic nucleotide second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.

activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.

activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

voltage-gated potassium channel complex

A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.

axon

The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

axon part

A part of an axon, a cell projection of a neuron.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

potassium channel complex

An ion channel complex through which potassium ions pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

neuron projection

A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

axon terminus

Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.

neuron projection terminus

The specialized, terminal region of a neuron projection such as an axon or a dendrite.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

synapse part

Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

synapse

The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

synapse part

Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

neuron projection terminus

The specialized, terminal region of a neuron projection such as an axon or a dendrite.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

axon terminus

Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.

axon part

A part of an axon, a cell projection of a neuron.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

voltage-gated potassium channel complex

A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.

voltage-gated potassium channel complex

A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.

peptide receptor activity

Combining with an extracellular or intracellular peptide to initiate a change in cell activity.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

inositol or phosphatidylinositol phosphodiesterase activity

NA

phosphoinositide phospholipase C activity

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.

phospholipase activity

Catalysis of the hydrolysis of a glycerophospholipid.

phospholipase C activity

Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

G-protein coupled receptor activity

A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

muscarinic acetylcholine receptor activity

Combining with acetylcholine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of muscarinic receptors.

serotonin receptor activity

Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

voltage-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.

voltage-gated potassium channel activity

Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.

delayed rectifier potassium channel activity

Catalysis of the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and activation is slow.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

potassium channel activity

Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

phosphoric diester hydrolase activity

Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

drug binding

Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.

neuropeptide receptor activity

Combining with a neuropeptide to initiate a change in cell activity.

G-protein coupled amine receptor activity

A receptor that binds an extracellular amine and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

peptide receptor activity, G-protein coupled

Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

acetylcholine receptor activity

Combining with acetylcholine to initiate a change in cell activity.

lipase activity

Catalysis of the hydrolysis of a lipid or phospholipid.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

hydrolase activity, acting on ester bonds

Catalysis of the hydrolysis of any ester bond.

G-protein coupled acetylcholine receptor activity

Combining with acetylcholine to initiate a change in cell activity via activation of a G protein.

passive transmembrane transporter activity

Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.

voltage-gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

voltage-gated cation channel activity

Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

neurotransmitter binding

Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.

acetylcholine binding

Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.

peptide binding

Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.

phosphoric ester hydrolase activity

Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.

neuropeptide binding

Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).

amine binding

Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group.

serotonin binding

Interacting selectively and non-covalently with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

acetylcholine binding

Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.

acetylcholine receptor activity

Combining with acetylcholine to initiate a change in cell activity.

neuropeptide receptor activity

Combining with a neuropeptide to initiate a change in cell activity.

peptide receptor activity

Combining with an extracellular or intracellular peptide to initiate a change in cell activity.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

neuropeptide receptor activity

Combining with a neuropeptide to initiate a change in cell activity.

acetylcholine receptor activity

Combining with acetylcholine to initiate a change in cell activity.

phospholipase C activity

Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

peptide receptor activity, G-protein coupled

Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.

phosphoinositide phospholipase C activity

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.

voltage-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.

voltage-gated cation channel activity

Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.

G-protein coupled acetylcholine receptor activity

Combining with acetylcholine to initiate a change in cell activity via activation of a G protein.

voltage-gated potassium channel activity

Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0007186	2.110e-08	3.393	20 ADRA1D, CHRM1, CHRM3, GPR123, GPR26, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR4, HTR6, KISS1R, OPRD1, PDYN, PNOC, PRLHR, RXFP3, SST, TRHR	416	G-protein coupled receptor protein signaling pathway
GO:0007268	2.661e-08	2.341	17 ARC, CHRM1, EGR3, GLRA3, GRIN2B, HRH1, HTR2A, HTR2C, HTR3A, HTR6, KISS1R, NETO1, PDYN, PNOC, SHC3, SLIT1, SST	287	synaptic transmission
GO:0007267	6.911e-08	4.519	22 ADCYAP1, ADRA1D, ARC, CHRM1, EGR3, FGF10, GLRA3, GRIN2B, HRH1, HTR2A, HTR2C, HTR3A, HTR6, KISS1R, NETO1, PCDH8, PCSK1, PDYN, PNOC, SHC3, SLIT1, SST	554	cell-cell signaling
GO:0019226	1.836e-07	2.692	17 ARC, CHRM1, EGR3, GLRA3, GRIN2B, HRH1, HTR2A, HTR2C, HTR3A, HTR6, KISS1R, NETO1, PDYN, PNOC, SHC3, SLIT1, SST	330	transmission of nerve impulse
GO:0006813	4.481e-07	0.9625	11 HTR2A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNH4, KCNS1, KCNV1, KCTD16, KCTD4	118	potassium ion transport
GO:0050877	1.388e-06	5.922	23 ADRA1D, ARC, CHRM1, CRYGA, EGR3, GLRA3, GRIN2B, GRPR, HRH1, HTR2A, HTR2C, HTR3A, HTR6, KISS1R, MAPK3, NETO1, OPRD1, PDYN, PNOC, SHC3, SLIT1, SST, TSHZ3	726	neurological system process
GO:0003008	5.646e-06	8.14	26 ADRA1D, ARC, CHRM1, CHRM3, CRYGA, EGR3, FGF10, GLRA3, GRIN2B, GRPR, HRH1, HTR2A, HTR2C, HTR3A, HTR6, KCNB2, KISS1R, MAPK3, NETO1, OPRD1, PDYN, PNOC, SHC3, SLIT1, SST, TSHZ3	998	system process
GO:0007166	1.456e-05	9.82	28 ADCYAP1, ADRA1D, CHRM1, CHRM3, EPHA5, FGF10, GPR123, GPR26, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR4, HTR6, KISS1R, MAPK3, OPRD1, PDYN, PNOC, PRLHR, RXFP3, SHC3, SST, TRHR, WNT1, WNT16	1204	cell surface receptor linked signaling pathway
GO:0006811	2.507e-05	5.408	20 CACNG3, GABRQ, GLRA3, GRIN2B, HTR2A, HTR2C, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, OPRD1	663	ion transport
GO:0019932	6.213e-05	1.648	11 ADRA1D, CHRM1, GPR26, HRH1, HTR1A, HTR2A, HTR4, HTR6, KISS1R, OPRD1, RXFP3	202	second-messenger-mediated signaling
GO:0030001	8.231e-05	3.344	15 CACNG3, GRIN2B, HTR2A, HTR2C, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNH4, KCNS1, KCNV1, KCTD16, KCTD4, OPRD1	410	metal ion transport
GO:0023052	1.757e-04	22.81	43 ADCYAP1, ADRA1D, ARC, CHRM1, CHRM3, CNTNAP5, EGR3, EPHA5, FGF10, GABRQ, GLRA3, GPR123, GPR26, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KCNH4, KISS1R, MAPK3, NETO1, OPRD1, PCDH8, PCSK1, PDYN, PLXNA4, PNOC, PRLHR, RXFP3, SHC3, SLC7A3, SLIT1, SPRED3, SST, TRHR, WNT1, WNT16	2797	signaling
GO:0023060	2.015e-04	16.45	35 ADRA1D, ARC, CHRM1, CHRM3, CNTNAP5, EGR3, FGF10, GABRQ, GLRA3, GPR123, GPR26, GRIN2B, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KCNH4, KISS1R, MAPK3, NETO1, OPRD1, PDYN, PLXNA4, PNOC, RXFP3, SHC3, SLC7A3, SLIT1, SPRED3, SST, WNT16	2017	signal transmission
GO:0023046	2.147e-04	16.5	35 ADRA1D, ARC, CHRM1, CHRM3, CNTNAP5, EGR3, FGF10, GABRQ, GLRA3, GPR123, GPR26, GRIN2B, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KCNH4, KISS1R, MAPK3, NETO1, OPRD1, PDYN, PLXNA4, PNOC, RXFP3, SHC3, SLC7A3, SLIT1, SPRED3, SST, WNT16	2023	signaling process
GO:0007154	2.637e-04	10.84	27 ADCYAP1, ADRA1D, ARC, CHRM1, EGR3, FGF10, FREM3, GLRA3, GRIN2B, HRH1, HTR2A, HTR2C, HTR3A, HTR6, KISS1R, NETO1, PCDH8, PCSK1, PDYN, PNOC, SHC3, SLC7A3, SLIT1, SPRED3, SST, WNT1, WNT16	1329	cell communication
GO:0007210	3.775e-04	0.04078	3 HTR1A, HTR2A, HTR2C	5	serotonin receptor signaling pathway
GO:0006812	4.361e-04	3.899	15 CACNG3, GRIN2B, HTR2A, HTR2C, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNH4, KCNS1, KCNV1, KCTD16, KCTD4, OPRD1	478	cation transport
GO:0015672	4.421e-04	2.072	11 HTR2A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNH4, KCNS1, KCNV1, KCTD16, KCTD4	254	monovalent inorganic cation transport
GO:0044057	5.185e-04	2.113	11 ADRA1D, ARC, CHRM3, FGF10, GRIN2B, HTR2A, KCNB2, KISS1R, NETO1, OPRD1, TSHZ3	259	regulation of system process
GO:0007610	3.135e-03	3.148	12 FGF10, GRIN2B, GRPR, HTR1A, HTR2A, HTR2C, KISS1R, NETO1, OPRD1, PRLHR, SHC3, SLIT1	386	behavior
GO:0007187	3.949e-03	0.7259	6 ADRA1D, GPR26, HTR1A, HTR4, HTR6, OPRD1	89	G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0035556	7.732e-03	7.781	19 ADRA1D, CHRM1, FGF10, GPR26, GRIN2B, HRH1, HTR1A, HTR2A, HTR2C, HTR4, HTR6, KISS1R, MAPK3, OPRD1, RXFP3, SHC3, SLC7A3, SPRED3, WNT16	954	intracellular signal transduction
GO:0007200	8.064e-03	0.2936	4 CHRM1, HRH1, HTR2A, RXFP3	36	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0019935	8.703e-03	0.8646	6 ADRA1D, GPR26, HTR1A, HTR4, HTR6, OPRD1	106	cyclic-nucleotide-mediated signaling
GO:0007156	9.064e-03	0.8727	6 CDH4, CDH8, CDH9, PCDH19, PCDH20, PCDH8	107	homophilic cell adhesion
GO:0051145	1.031e-02	0.1305	3 FGF10, MKL2, TSHZ3	16	smooth muscle cell differentiation
GO:0019233	1.034e-02	0.3181	4 GRIN2B, HTR2A, MAPK3, OPRD1	39	sensory perception of pain
GO:0023033	1.404e-02	16.52	30 ADCYAP1, ADRA1D, CHRM1, CHRM3, EPHA5, FGF10, GPR123, GPR26, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR4, HTR6, KISS1R, MAPK3, OPRD1, PDYN, PNOC, PRLHR, RXFP3, SHC3, SLC7A3, SPRED3, SST, TRHR, WNT1, WNT16	2025	signaling pathway
GO:0031644	1.749e-02	1.02	6 ARC, GRIN2B, HTR2A, KISS1R, NETO1, OPRD1	125	regulation of neurological system process
GO:0007202	1.950e-02	0.3915	4 CHRM1, HRH1, HTR2A, RXFP3	48	activation of phospholipase C activity
GO:0010863	1.950e-02	0.3915	4 CHRM1, HRH1, HTR2A, RXFP3	48	positive regulation of phospholipase C activity
GO:0010518	2.305e-02	0.416	4 CHRM1, HRH1, HTR2A, RXFP3	51	positive regulation of phospholipase activity
GO:0010517	2.544e-02	0.4323	4 CHRM1, HRH1, HTR2A, RXFP3	53	regulation of phospholipase activity
GO:0007611	2.570e-02	0.7504	5 GRIN2B, GRPR, HTR2A, NETO1, SHC3	92	learning or memory
GO:0032501	2.647e-02	26.92	41 ADRA1D, ARC, BCL11B, CDH4, CHRM1, CHRM3, CRYGA, DLX1, EGR3, FGF10, GLRA3, GRIN2B, GRPR, HRH1, HTR2A, HTR2C, HTR3A, HTR6, IL1RAPL2, KCNB2, KISS1R, LPPR4, MAPK3, MEPE, MKL2, MYO16, NETO1, OPRD1, PCDH8, PCSK1, PDYN, PLXNA4, PNOC, SHC3, SLIT1, SPRED3, SST, TSHZ3, WNT1, WNT16, XYLT1	3300	multicellular organismal process
GO:0009190	2.846e-02	0.7749	5 ADCYAP1, GPR26, HTR1A, HTR2C, OPRD1	95	cyclic nucleotide biosynthetic process
GO:0048168	2.871e-02	0.2039	3 ARC, GRIN2B, NETO1	25	regulation of neuronal synaptic plasticity
GO:0007631	2.947e-02	0.4568	4 GRIN2B, HTR1A, HTR2C, PRLHR	56	feeding behavior
GO:0060193	2.947e-02	0.4568	4 CHRM1, HRH1, HTR2A, RXFP3	56	positive regulation of lipase activity
GO:0007165	3.125e-02	14.32	26 ADRA1D, CHRM1, CHRM3, CNTNAP5, FGF10, GABRQ, GPR123, GPR26, GRIN2B, HRH1, HTR1A, HTR2A, HTR2C, HTR4, HTR6, IL1RAPL2, KISS1R, MAPK3, OPRD1, PLXNA4, PNOC, RXFP3, SHC3, SLC7A3, SPRED3, WNT16	1756	signal transduction
GO:0050890	3.149e-02	0.7993	5 GRIN2B, GRPR, HTR2A, NETO1, SHC3	98	cognition
GO:0045747	3.413e-02	0.0571	2 FGF10, WNT1	7	positive regulation of Notch signaling pathway
GO:0023034	3.421e-02	9.837	20 ADRA1D, CHRM1, FGF10, GPR26, GRIN2B, HRH1, HTR1A, HTR2A, HTR2C, HTR4, HTR6, KISS1R, MAPK3, OPRD1, RXFP3, SHC3, SLC7A3, SPRED3, WNT1, WNT16	1206	intracellular signaling pathway
GO:0051239	3.907e-02	7.121	16 ADRA1D, ARC, CDH4, CHRM3, DLX1, FGF10, GRIN2B, HTR2A, KCNB2, KISS1R, MKL2, NETO1, OPRD1, SLIT1, TSHZ3, XYLT1	873	regulation of multicellular organismal process
GO:0048015	4.236e-02	0.522	4 CHRM1, HRH1, HTR2A, RXFP3	64	phosphoinositide-mediated signaling
GO:0007586	4.418e-02	0.5302	4 CHRM3, FGF10, HTR3A, SST	65	digestion
GO:0060191	4.418e-02	0.5302	4 CHRM1, HRH1, HTR2A, RXFP3	65	regulation of lipase activity
GO:0050804	4.444e-02	0.8891	5 ARC, GRIN2B, HTR2A, KISS1R, NETO1	109	regulation of synaptic transmission
GO:0007188	4.777e-02	0.5465	4 ADRA1D, GPR26, HTR1A, OPRD1	67	G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0009187	4.975e-02	0.9217	5 ADCYAP1, GPR26, HTR1A, HTR2C, OPRD1	113	cyclic nucleotide metabolic process

Id	Pvalue	ExpCount	Count	Size	Term
GO:0016021	5.771e-13	31.81	70 ADRA1D, C11orf87, C13orf36, C5orf40, CACNG3, CDH4, CDH8, CDH9, CHRM1, CHRM3, CHST1, CNTNAP5, EPHA5, FREM3, GABRQ, GLRA3, GPR123, GPR150, GPR26, GPR45, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KISS1R, LOC644070, LPPR3, LPPR4, LPPR5, LRFN2, LRRC55, LRTM2, MMP17, NETO1, OPRD1, PCDH19, PCDH20, PCDH8, PLD3, PLXNA4, PRLHR, PROKR2, PRRG3, RXFP3, SLC35E4, SLC7A3, ST6GALNAC5, STYK1, TMEM132D, TRHR, XKR4, XYLT1	3638	integral to membrane
GO:0031224	1.768e-12	32.51	70 ADRA1D, C11orf87, C13orf36, C5orf40, CACNG3, CDH4, CDH8, CDH9, CHRM1, CHRM3, CHST1, CNTNAP5, EPHA5, FREM3, GABRQ, GLRA3, GPR123, GPR150, GPR26, GPR45, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KISS1R, LOC644070, LPPR3, LPPR4, LPPR5, LRFN2, LRRC55, LRTM2, MMP17, NETO1, OPRD1, PCDH19, PCDH20, PCDH8, PLD3, PLXNA4, PRLHR, PROKR2, PRRG3, RXFP3, SLC35E4, SLC7A3, ST6GALNAC5, STYK1, TMEM132D, TRHR, XKR4, XYLT1	3717	intrinsic to membrane
GO:0005886	1.850e-11	22.95	57 ADRA1D, ARC, CACNG3, CBLN4, CDH4, CDH8, CDH9, CHRM1, CHRM3, EPHA5, FGF10, GABRQ, GLRA3, GPR123, GPR150, GPR26, GPR45, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KISS1R, LPPR4, LRFN2, MMP17, MYO16, NETO1, OPRD1, PCDH19, PCDH20, PCDH8, PDYN, PLXNA4, PRLHR, PROKR2, RXFP3, SLC7A3, SPRED3, STYK1, TRHR	2624	plasma membrane
GO:0005887	7.111e-11	8.08	33 ADRA1D, CDH4, CHRM1, CHRM3, EPHA5, GABRQ, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR3A, HTR4, HTR6, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, LPPR4, MMP17, OPRD1, PCDH8, PRLHR, RXFP3, TRHR	924	integral to plasma membrane
GO:0008076	9.099e-11	0.6296	12 KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	72	voltage-gated potassium channel complex
GO:0034705	9.099e-11	0.6296	12 KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	72	potassium channel complex
GO:0031226	1.218e-10	8.255	33 ADRA1D, CDH4, CHRM1, CHRM3, EPHA5, GABRQ, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR3A, HTR4, HTR6, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, LPPR4, MMP17, OPRD1, PCDH8, PRLHR, RXFP3, TRHR	944	intrinsic to plasma membrane
GO:0044425	1.781e-10	37.49	72 ADRA1D, ARC, C11orf87, C13orf36, C5orf40, CACNG3, CBLN4, CDH4, CDH8, CDH9, CHRM1, CHRM3, CHST1, CNTNAP5, EPHA5, FREM3, GABRQ, GLRA3, GPR123, GPR150, GPR26, GPR45, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KISS1R, LOC644070, LPPR3, LPPR4, LPPR5, LRFN2, LRRC55, LRTM2, MMP17, NETO1, OPRD1, PCDH19, PCDH20, PCDH8, PLD3, PLXNA4, PRLHR, PROKR2, PRRG3, RXFP3, SLC35E4, SLC7A3, ST6GALNAC5, STYK1, TMEM132D, TRHR, XKR4, XYLT1	4287	membrane part
GO:0034703	1.101e-09	0.9882	13 CACNG3, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	113	cation channel complex
GO:0034702	1.292e-09	1.487	15 CACNG3, GABRQ, GLRA3, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	170	ion channel complex
GO:0016020	1.458e-08	45.02	76 ADRA1D, ARC, C11orf87, C13orf36, C5orf40, CACNG3, CBLN4, CDH4, CDH8, CDH9, CHRM1, CHRM3, CHST1, CNTNAP5, EPHA5, FGF10, FREM3, GABRQ, GLRA3, GPR123, GPR150, GPR26, GPR45, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KISS1R, LOC644070, LPPR3, LPPR4, LPPR5, LRFN2, LRRC55, LRTM2, MMP17, MYO16, NETO1, OPRD1, PCDH19, PCDH20, PCDH8, PDYN, PLD3, PLXNA4, PRLHR, PROKR2, PRRG3, RXFP3, SLC35E4, SLC7A3, SPRED3, ST6GALNAC5, STYK1, TMEM132D, TRHR, XKR4, XYLT1	5148	membrane
GO:0044459	2.361e-08	13.92	39 ADRA1D, ARC, CACNG3, CBLN4, CDH4, CHRM1, CHRM3, EPHA5, GABRQ, GLRA3, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR3A, HTR4, HTR6, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, LPPR4, LRFN2, MMP17, NETO1, OPRD1, PCDH8, PRLHR, RXFP3, TRHR	1592	plasma membrane part
GO:0045211	4.901e-07	1.093	11 ARC, CHRM1, CHRM3, GABRQ, GLRA3, GRIN2B, HTR3A, KCTD16, LRFN2, NETO1, OPRD1	125	postsynaptic membrane
GO:0044456	8.054e-05	1.898	11 ARC, CHRM1, CHRM3, GABRQ, GLRA3, GRIN2B, HTR3A, KCTD16, LRFN2, NETO1, OPRD1	217	synapse part
GO:0045202	2.055e-04	2.536	12 ARC, CBLN4, CHRM1, CHRM3, GABRQ, GLRA3, GRIN2B, HTR3A, KCTD16, LRFN2, NETO1, OPRD1	290	synapse
GO:0043679	2.861e-03	0.2798	4 CHRM1, CHRM3, OPRD1, PCSK1	32	axon terminus
GO:0044306	2.861e-03	0.2798	4 CHRM1, CHRM3, OPRD1, PCSK1	32	neuron projection terminus
GO:0033267	3.206e-03	0.5334	5 CHRM1, CHRM3, HTR1A, OPRD1, PCSK1	61	axon part
GO:0032279	1.043e-02	0.04373	2 CHRM1, CHRM3	5	asymmetric synapse
GO:0030054	1.459e-02	3.69	11 ARC, CBLN4, CHRM1, CHRM3, GABRQ, GLRA3, GRIN2B, HTR3A, KCTD16, LRFN2, NETO1	422	cell junction
GO:0030425	2.294e-02	1.303	6 ARC, CHRM1, CHRM3, GRIN2B, HTR2A, PCSK1	149	dendrite
GO:0014069	2.823e-02	0.5684	4 ARC, CHRM1, GRIN2B, NETO1	65	postsynaptic density
GO:0031012	3.711e-02	2.492	8 ADAMTS8, FGF10, FREM3, GRIN2B, MEPE, MMP17, WNT1, WNT16	285	extracellular matrix
GO:0044463	4.024e-02	2.536	8 ARC, CHRM1, CHRM3, GRIN2B, HTR1A, HTR2A, OPRD1, PCSK1	290	cell projection part

Id	Pvalue	ExpCount	Count	Size	Term
GO:0008227	9.556e-12	0.2438	10 ADRA1D, CHRM1, CHRM3, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6	29	G-protein coupled amine receptor activity
GO:0004930	4.394e-10	3.06	21 ADRA1D, CHRM1, CHRM3, GPR123, GPR150, GPR26, GPR45, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, KISS1R, OPRD1, PRLHR, PROKR2, RXFP3, TRHR	364	G-protein coupled receptor activity
GO:0005249	6.364e-10	0.6809	12 KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	81	voltage-gated potassium channel activity
GO:0022843	2.945e-09	0.992	13 CACNG3, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	118	voltage-gated cation channel activity
GO:0022836	3.558e-09	2.076	17 CACNG3, GABRQ, GLRA3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	247	gated channel activity
GO:0004888	6.167e-09	5.75	26 ADRA1D, CHRM1, CHRM3, EPHA5, GABRQ, GPR123, GPR150, GPR26, GPR45, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KISS1R, OPRD1, PLXNA4, PRLHR, PROKR2, RXFP3, TRHR	684	transmembrane receptor activity
GO:0005267	1.373e-08	0.9079	12 KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	108	potassium channel activity
GO:0004871	3.375e-08	11.3	35 ADCYAP1, ADRA1D, CHRM1, CHRM3, EPHA5, GABRQ, GLRA3, GPR123, GPR150, GPR26, GPR45, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KCNH4, KISS1R, MAPK3, NETO1, NPAS4, OPRD1, PLXNA4, PRLHR, PROKR2, RXFP3, SHC3, TRHR, WNT1, WNT16	1344	signal transducer activity
GO:0060089	3.375e-08	11.3	35 ADCYAP1, ADRA1D, CHRM1, CHRM3, EPHA5, GABRQ, GLRA3, GPR123, GPR150, GPR26, GPR45, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KCNH4, KISS1R, MAPK3, NETO1, NPAS4, OPRD1, PLXNA4, PRLHR, PROKR2, RXFP3, SHC3, TRHR, WNT1, WNT16	1344	molecular transducer activity
GO:0005261	5.464e-08	1.858	15 CACNG3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	221	cation channel activity
GO:0005216	5.719e-08	2.53	17 CACNG3, GABRQ, GLRA3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	301	ion channel activity
GO:0005244	5.949e-08	1.295	13 CACNG3, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	154	voltage-gated ion channel activity
GO:0022832	5.949e-08	1.295	13 CACNG3, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	154	voltage-gated channel activity
GO:0022838	8.853e-08	2.614	17 CACNG3, GABRQ, GLRA3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	311	substrate-specific channel activity
GO:0015267	1.427e-07	2.707	17 CACNG3, GABRQ, GLRA3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	322	channel activity
GO:0022803	1.490e-07	2.715	17 CACNG3, GABRQ, GLRA3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	323	passive transmembrane transporter activity
GO:0004872	5.497e-07	8.339	28 ADRA1D, CHRM1, CHRM3, EPHA5, GABRQ, GLRA3, GPR123, GPR150, GPR26, GPR45, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL2, KISS1R, NETO1, OPRD1, PLXNA4, PRLHR, PROKR2, RXFP3, TRHR	992	receptor activity
GO:0004993	1.724e-06	0.09247	5 HTR1A, HTR2A, HTR2C, HTR3A, HTR4	11	serotonin receptor activity
GO:0051378	1.320e-05	0.05885	4 HTR1A, HTR2A, HTR2C, HTR3A	7	serotonin binding
GO:0015075	1.420e-05	4.75	19 ADAMTS8, CACNG3, GABRQ, GLRA3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SLC7A3	565	ion transmembrane transporter activity
GO:0042165	3.687e-05	0.4876	7 CHRM1, CHRM3, GRIN2B, GRPR, KISS1R, PRLHR, PROKR2	58	neurotransmitter binding
GO:0008324	4.435e-05	3.674	16 CACNG3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SLC7A3	437	cation transmembrane transporter activity
GO:0022891	9.500e-05	5.456	19 ADAMTS8, CACNG3, GABRQ, GLRA3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SLC7A3	649	substrate-specific transmembrane transporter activity
GO:0030594	2.098e-04	0.4203	6 CHRM1, CHRM3, GRPR, KISS1R, PRLHR, PROKR2	50	neurotransmitter receptor activity
GO:0022857	3.160e-04	5.985	19 ADAMTS8, CACNG3, GABRQ, GLRA3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SLC7A3	712	transmembrane transporter activity
GO:0043176	4.516e-04	0.7398	7 CHRM1, CHRM3, GRIN2B, HTR1A, HTR2A, HTR2C, HTR3A	88	amine binding
GO:0022892	6.379e-04	6.338	19 ADAMTS8, CACNG3, GABRQ, GLRA3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SLC7A3	754	substrate-specific transporter activity
GO:0008144	1.543e-03	0.3783	5 CHRM1, CHRM3, HTR1A, HTR2A, HTR2C	45	drug binding
GO:0005251	1.961e-03	0.07566	3 KCNA3, KCNB2, KCNS1	9	delayed rectifier potassium channel activity
GO:0004434	2.136e-03	0.2102	4 CHRM1, CHRM3, HTR2A, HTR2C	25	inositol or phosphatidylinositol phosphodiesterase activity
GO:0004435	2.136e-03	0.2102	4 CHRM1, CHRM3, HTR2A, HTR2C	25	phosphoinositide phospholipase C activity
GO:0001653	2.521e-03	0.6893	6 GRPR, KISS1R, OPRD1, PRLHR, PROKR2, RXFP3	82	peptide receptor activity
GO:0008528	2.521e-03	0.6893	6 GRPR, KISS1R, OPRD1, PRLHR, PROKR2, RXFP3	82	peptide receptor activity, G-protein coupled
GO:0004629	3.547e-03	0.2438	4 CHRM1, CHRM3, HTR2A, HTR2C	29	phospholipase C activity
GO:0008188	3.975e-03	0.2522	4 GRPR, KISS1R, PRLHR, PROKR2	30	neuropeptide receptor activity
GO:0042923	4.433e-03	0.2606	4 GRPR, KISS1R, PRLHR, PROKR2	31	neuropeptide binding
GO:0005215	5.813e-03	7.667	19 ADAMTS8, CACNG3, GABRQ, GLRA3, GRIN2B, HTR3A, KCNA3, KCNA4, KCNB2, KCNF1, KCNG1, KCNG3, KCNH4, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SLC7A3	912	transporter activity
GO:0004981	6.779e-03	0.02522	2 CHRM1, CHRM3	3	muscarinic acetylcholine receptor activity
GO:0016907	6.779e-03	0.02522	2 CHRM1, CHRM3	3	G-protein coupled acetylcholine receptor activity
GO:0042277	8.701e-03	1.278	7 GRPR, KISS1R, OPRD1, PCSK1, PRLHR, PROKR2, RXFP3	152	peptide binding
GO:0004620	9.038e-03	0.5885	5 CHRM1, CHRM3, HTR2A, HTR2C, PLD3	70	phospholipase activity
GO:0008081	1.172e-02	0.6305	5 CHRM1, CHRM3, HTR2A, HTR2C, PLD3	75	phosphoric diester hydrolase activity
GO:0001515	1.187e-02	0.03363	2 PDYN, PNOC	4	opioid peptide activity
GO:0016298	1.699e-02	0.6977	5 CHRM1, CHRM3, HTR2A, HTR2C, PLD3	83	lipase activity
GO:0004969	2.405e-02	0.05044	2 HRH1, HTR6	6	histamine receptor activity
GO:0005230	3.004e-02	0.4876	4 GABRQ, GLRA3, GRIN2B, HTR3A	58	extracellular ligand-gated ion channel activity
GO:0008195	3.772e-02	0.06725	2 LPPR3, LPPR4	8	phosphatidate phosphatase activity
GO:0004983	4.568e-02	0.07566	2 PRLHR, PROKR2	9	neuropeptide Y receptor activity

Id	Pvalue	ExpCount	Count	Size	Term
04080	5.083e-12	1.665	17 ADRA1D, CHRM1, CHRM3, GABRQ, GLRA3, GRIN2B, GRPR, HRH1, HTR1A, HTR2A, HTR2C, HTR4, HTR6, KISS1R, OPRD1, PRLHR, TRHR	206	Neuroactive ligand-receptor interaction
04020	6.532e-06	1.172	10 ADRA1D, CHRM1, CHRM3, GRPR, HRH1, HTR2A, HTR2C, HTR4, HTR6, TRHR	145	Calcium signaling pathway

No enriched terms

No enriched terms

Entrez genes

ADAMTS8ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ENSG00000134917), score: 0.72 ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary) (ENSG00000141433), score: 0.74 ADRA1Dadrenergic, alpha-1D-, receptor (ENSG00000171873), score: 0.76 ARCactivity-regulated cytoskeleton-associated protein (ENSG00000198576), score: 0.78 BCL11BB-cell CLL/lymphoma 11B (zinc finger protein) (ENSG00000127152), score: 0.71 BTBD9BTB (POZ) domain containing 9 (ENSG00000183826), score: 0.74 C11orf87chromosome 11 open reading frame 87 (ENSG00000185742), score: 0.71 C13orf36chromosome 13 open reading frame 36 (ENSG00000180440), score: 0.84 C1QL2complement component 1, q subcomponent-like 2 (ENSG00000144119), score: 0.7 C5orf40chromosome 5 open reading frame 40 (ENSG00000172568), score: 0.71 CACNG3calcium channel, voltage-dependent, gamma subunit 3 (ENSG00000006116), score: 0.72 CBLN4cerebellin 4 precursor (ENSG00000054803), score: 0.75 CDH4cadherin 4, type 1, R-cadherin (retinal) (ENSG00000179242), score: 0.7 CDH8cadherin 8, type 2 (ENSG00000150394), score: 0.76 CDH9cadherin 9, type 2 (T1-cadherin) (ENSG00000113100), score: 0.7 CHRM1cholinergic receptor, muscarinic 1 (ENSG00000168539), score: 0.72 CHRM3cholinergic receptor, muscarinic 3 (ENSG00000133019), score: 0.76 CHST1carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 (ENSG00000175264), score: 0.7 CNTNAP5contactin associated protein-like 5 (ENSG00000155052), score: 0.8 CRYGAcrystallin, gamma A (ENSG00000168582), score: 0.83 DLX1distal-less homeobox 1 (ENSG00000144355), score: 0.7 EGR3early growth response 3 (ENSG00000179388), score: 0.76 EPHA5EPH receptor A5 (ENSG00000145242), score: 0.72 FAM19A1family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 (ENSG00000183662), score: 0.77 FAM92Bfamily with sequence similarity 92, member B (ENSG00000153789), score: 0.72 FERD3LFer3-like (Drosophila) (ENSG00000146618), score: 0.93 FGF10fibroblast growth factor 10 (ENSG00000070193), score: 0.71 FREM3FRAS1 related extracellular matrix 3 (ENSG00000183090), score: 0.78 GABRQgamma-aminobutyric acid (GABA) receptor, theta (ENSG00000147402), score: 1 GLRA3glycine receptor, alpha 3 (ENSG00000145451), score: 0.73 GPR123G protein-coupled receptor 123 (ENSG00000197177), score: 0.76 GPR150G protein-coupled receptor 150 (ENSG00000178015), score: 0.74 GPR26G protein-coupled receptor 26 (ENSG00000154478), score: 0.75 GPR45G protein-coupled receptor 45 (ENSG00000135973), score: 0.74 GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B (ENSG00000150086), score: 0.75 HRH1histamine receptor H1 (ENSG00000196639), score: 0.74 HTR1A5-hydroxytryptamine (serotonin) receptor 1A (ENSG00000178394), score: 0.85 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (ENSG00000102468), score: 0.75 HTR2C5-hydroxytryptamine (serotonin) receptor 2C (ENSG00000147246), score: 0.87 HTR3A5-hydroxytryptamine (serotonin) receptor 3A (ENSG00000166736), score: 0.74 HTR45-hydroxytryptamine (serotonin) receptor 4 (ENSG00000164270), score: 0.84 HTR65-hydroxytryptamine (serotonin) receptor 6 (ENSG00000158748), score: 0.97 IL1RAPL2interleukin 1 receptor accessory protein-like 2 (ENSG00000189108), score: 0.75 KCNA3potassium voltage-gated channel, shaker-related subfamily, member 3 (ENSG00000177272), score: 0.74 KCNA4potassium voltage-gated channel, shaker-related subfamily, member 4 (ENSG00000182255), score: 0.77 KCNB2potassium voltage-gated channel, Shab-related subfamily, member 2 (ENSG00000182674), score: 0.72 KCNF1potassium voltage-gated channel, subfamily F, member 1 (ENSG00000162975), score: 0.73 KCNG1potassium voltage-gated channel, subfamily G, member 1 (ENSG00000026559), score: 0.76 KCNG3potassium voltage-gated channel, subfamily G, member 3 (ENSG00000171126), score: 0.78 KCNH4potassium voltage-gated channel, subfamily H (eag-related), member 4 (ENSG00000089558), score: 0.82 KCNS1potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 (ENSG00000124134), score: 0.73 KCNS2potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 (ENSG00000156486), score: 0.76 KCNV1potassium channel, subfamily V, member 1 (ENSG00000164794), score: 0.79 KCTD16potassium channel tetramerisation domain containing 16 (ENSG00000183775), score: 0.71 KCTD4potassium channel tetramerisation domain containing 4 (ENSG00000180332), score: 0.71 KISS1RKISS1 receptor (ENSG00000116014), score: 0.71 LOC100293905similar to gastrin-releasing peptide receptor (ENSG00000126010), score: 0.71 LOC644070germ cell-specific gene 1-like protein 2-like (ENSG00000214978), score: 0.73 LPPR3lipid phosphate phosphatase-related protein type 3 (ENSG00000129951), score: 0.74 LPPR4lipid phosphate phosphatase-related protein type 4 (ENSG00000117600), score: 0.75 LPPR5lipid phosphate phosphatase-related protein type 5 (ENSG00000117598), score: 0.76 LRFN2leucine rich repeat and fibronectin type III domain containing 2 (ENSG00000156564), score: 0.77 LRRC55leucine rich repeat containing 55 (ENSG00000183908), score: 0.72 LRTM2leucine-rich repeats and transmembrane domains 2 (ENSG00000166159), score: 0.76 MAPK3mitogen-activated protein kinase 3 (ENSG00000102882), score: 0.73 MEPEmatrix extracellular phosphoglycoprotein (ENSG00000152595), score: 0.74 MKL2MKL/myocardin-like 2 (ENSG00000186260), score: 0.7 MMP17matrix metallopeptidase 17 (membrane-inserted) (ENSG00000198598), score: 0.73 MYO16myosin XVI (ENSG00000041515), score: 0.72 NETO1neuropilin (NRP) and tolloid (TLL)-like 1 (ENSG00000166342), score: 0.72 NPAS4neuronal PAS domain protein 4 (ENSG00000174576), score: 0.79 OPRD1opioid receptor, delta 1 (ENSG00000116329), score: 0.87 PCDH19protocadherin 19 (ENSG00000165194), score: 0.82 PCDH20protocadherin 20 (ENSG00000197991), score: 0.75 PCDH8protocadherin 8 (ENSG00000136099), score: 0.79 PCSK1proprotein convertase subtilisin/kexin type 1 (ENSG00000175426), score: 0.73 PDYNprodynorphin (ENSG00000101327), score: 0.85 PLD3phospholipase D family, member 3 (ENSG00000105223), score: 0.71 PLXNA4plexin A4 (ENSG00000221866), score: 0.76 PNOCprepronociceptin (ENSG00000168081), score: 0.72 PRLHRprolactin releasing hormone receptor (ENSG00000119973), score: 0.82 PROKR2prokineticin receptor 2 (ENSG00000101292), score: 0.91 PRRG3proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) (ENSG00000130032), score: 0.77 RXFP3relaxin/insulin-like family peptide receptor 3 (ENSG00000182631), score: 0.81 SERPINB13serpin peptidase inhibitor, clade B (ovalbumin), member 13 (ENSG00000197641), score: 0.77 SH2D4BSH2 domain containing 4B (ENSG00000178217), score: 0.76 SH2D5SH2 domain containing 5 (ENSG00000189410), score: 0.71 SHC3SHC (Src homology 2 domain containing) transforming protein 3 (ENSG00000148082), score: 0.74 SLC35E4solute carrier family 35, member E4 (ENSG00000100036), score: 0.7 SLC7A3solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 (ENSG00000165349), score: 0.87 SLIT1slit homolog 1 (Drosophila) (ENSG00000187122), score: 0.75 SPRED3sprouty-related, EVH1 domain containing 3 (ENSG00000188766), score: 0.78 SSTsomatostatin (ENSG00000157005), score: 0.73 ST6GALNAC5ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ENSG00000117069), score: 0.73 STYK1serine/threonine/tyrosine kinase 1 (ENSG00000060140), score: 0.76 TMEM132Dtransmembrane protein 132D (ENSG00000151952), score: 0.75 TRHRthyrotropin-releasing hormone receptor (ENSG00000174417), score: 0.87 TSHZ3teashirt zinc finger homeobox 3 (ENSG00000121297), score: 0.71 VWC2Lvon Willebrand factor C domain-containing protein 2-like (ENSG00000174453), score: 0.74 WNT1wingless-type MMTV integration site family, member 1 (ENSG00000125084), score: 0.77 WNT16wingless-type MMTV integration site family, member 16 (ENSG00000002745), score: 0.78 XKR4XK, Kell blood group complex subunit-related family, member 4 (ENSG00000206579), score: 0.82 XYLT1xylosyltransferase I (ENSG00000103489), score: 0.72 ZNF831zinc finger protein 831 (ENSG00000124203), score: 0.88

Non-Entrez genes

ENSG00000100036Unknown, score: 0.92

Id	species	tissue	sex	individual
ppa_br_f1_ca1	ppa	br	f	1
hsa_br_m3_ca1	hsa	br	m	3
ppy_br_f_ca1	ppy	br	f	_
hsa_br_m7_ca1	hsa	br	m	7
mml_br_m1_ca1	mml	br	m	1
mml_br_f_ca1	mml	br	f	_
ppy_br_m_ca1	ppy	br	m	_
mml_br_m2_ca1	mml	br	m	2