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skeletal system development

The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

regulation of systemic arterial blood pressure by hormone

The process by which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.

regionalization

The pattern specification process by which an axis or axes is subdivided in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

circulatory system process

A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.

regulation of systemic arterial blood pressure mediated by a chemical signal

The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.

regulation of systemic arterial blood pressure

The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.

transcription

The cellular synthesis of either RNA on a template of DNA or DNA on a template of RNA.

transcription, DNA-dependent

The cellular synthesis of RNA on a template of DNA.

regulation of transcription, DNA-dependent

Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription.

nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

phosphate transport

The directed movement of phosphate into, out of, within or between cells by means of some external agent such as a transporter or pore.

anion transport

The directed movement of anions, atoms or small molecules with a net negative charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

embryo development

The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.

pattern specification process

Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

blood circulation

The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

regulation of blood pressure

Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.

biosynthetic process

The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

embryo development ending in birth or egg hatching

The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.

regulation of biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.

anterior/posterior pattern formation

The regionalization process by which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

proximal/distal pattern formation

The regionalization process by which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

gene expression

The process by which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.

regulation of gene expression

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.

regulation of macromolecule biosynthetic process

Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

inorganic anion transport

The directed movement of inorganic anions into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.

organic anion transport

The directed movement of organic anions into, out of, within or between cells by means of some external agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.

RNA metabolic process

The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

cell-cell adhesion

The attachment of one cell to another cell via adhesion molecules.

calcium-independent cell-cell adhesion

The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

biological adhesion

The attachment of a cell or organism to a substrate or other organism.

thyroid gland development

The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

regulation of cellular biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

RNA biosynthetic process

The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

endocrine system development

Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.

homeostatic process

Any biological process involved in the maintenance of an internal steady-state.

chordate embryonic development

The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

regulation of transcription

Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA.

ion homeostasis

Any process involved in the maintenance of an internal steady-state of ions within an organism or cell.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

embryonic organ morphogenesis

Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

embryonic organ development

Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

embryonic morphogenesis

The process by which anatomical structures are generated and organized during the embryonic phase. Morphogenesis pertains to the creation of form. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.

embryonic skeletal system morphogenesis

The process by which the anatomical structures of the skeleton are generated and organized during the embryonic phase. Morphogenesis pertains to the creation of form.

skeletal system morphogenesis

The process by which the anatomical structures of the skeleton are generated and organized. Morphogenesis pertains to the creation of form.

embryonic skeletal system development

The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

gland development

The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

chemical homeostasis

Any biological process involved in the maintenance of an internal steady-state of a chemical.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

endocrine process

The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.

regulation of nitrogen compound metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of RNA metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.

di-, tri-valent inorganic anion homeostasis

Any process involved in the maintenance of an internal steady-state of divalent or trivalent inorganic anions within an organism or cell.

phosphate ion homeostasis

Any process involved in the maintenance of an internal steady-state of phosphate ions within an organism or cell.

anion homeostasis

Any process involved in the maintenance of an internal steady-state of anions within an organism or cell.

regulation of macromolecule metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

regulation of primary metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

nucleic acid metabolic process

Any cellular metabolic process involving nucleic acids.

all

NA

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.

regulation of nitrogen compound metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of macromolecule metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

regulation of primary metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

embryo development

The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.

pattern specification process

Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.

embryonic morphogenesis

The process by which anatomical structures are generated and organized during the embryonic phase. Morphogenesis pertains to the creation of form. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of macromolecule biosynthetic process

Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of cellular biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of cellular biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

regulation of macromolecule biosynthetic process

Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of gene expression

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

embryonic organ morphogenesis

Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

embryonic organ morphogenesis

Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

embryonic organ development

Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

regulation of RNA metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.

regulation of transcription

Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA.

transcription

The cellular synthesis of either RNA on a template of DNA or DNA on a template of RNA.

regulation of transcription

Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA.

regulation of transcription

Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA.

transcription, DNA-dependent

The cellular synthesis of RNA on a template of DNA.

regulation of transcription

Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA.

RNA biosynthetic process

The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers.

regulation of RNA metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.

transcription

The cellular synthesis of either RNA on a template of DNA or DNA on a template of RNA.

RNA metabolic process

The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

regulation of blood pressure

Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.

skeletal system morphogenesis

The process by which the anatomical structures of the skeleton are generated and organized. Morphogenesis pertains to the creation of form.

embryonic skeletal system morphogenesis

The process by which the anatomical structures of the skeleton are generated and organized during the embryonic phase. Morphogenesis pertains to the creation of form.

embryonic skeletal system development

The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.

thyroid gland development

The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.

regulation of transcription, DNA-dependent

Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription.

regulation of transcription, DNA-dependent

Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription.

embryonic skeletal system morphogenesis

The process by which the anatomical structures of the skeleton are generated and organized during the embryonic phase. Morphogenesis pertains to the creation of form.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

regulation of systemic arterial blood pressure by hormone

The process by which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

proton-transporting two-sector ATPase complex

A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

vacuolar membrane

The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

basolateral plasma membrane

The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

vacuolar proton-transporting V-type ATPase complex

A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.

organelle membrane

The lipid bilayer surrounding an organelle.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

proton-transporting V-type ATPase complex

A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

vacuolar part

Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

organelle membrane

The lipid bilayer surrounding an organelle.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

organelle membrane

The lipid bilayer surrounding an organelle.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

proton-transporting two-sector ATPase complex

A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.

vacuolar membrane

The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

vacuolar proton-transporting V-type ATPase complex

A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

vacuolar part

Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

vacuolar proton-transporting V-type ATPase complex

A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.

vacuolar part

Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

nucleic acid binding

Interacting selectively and non-covalently with any nucleic acid.

DNA binding

Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).

sequence-specific DNA binding transcription factor activity

Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

inorganic anion exchanger activity

NA

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

anion transmembrane transporter activity

Catalysis of the transfer of a negatively charged ion from one side of a membrane to the other.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

monovalent inorganic cation transmembrane transporter activity

Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

inorganic anion transmembrane transporter activity

Catalysis of the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.

phosphate transmembrane transporter activity

Catalysis of the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.

symporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

solute:cation symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).

antiporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

solute:solute antiporter activity

Catalysis of the reaction: solute A(out) + solute B(in) = solute A(in) + solute B(out).

anion:anion antiporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).

sodium-dependent phosphate transmembrane transporter activity

Catalysis of the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other, requiring sodium ions.

anion exchanger activity

NA

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

sequence-specific DNA binding

Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

solute:cation symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).

anion:anion antiporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).

Id	Pvalue	ExpCount	Count	Size	Term
GO:0009952	3.880e-11	1.471	17 CER1, HOXA10, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9	116	anterior/posterior pattern formation
GO:0048706	9.385e-10	0.8747	13 HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC6, HOXD1, HOXD10, HOXD3, HOXD4, HOXD9, TFAP2A	69	embryonic skeletal system development
GO:0048704	4.151e-09	0.6085	11 HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXD10, HOXD3, HOXD4, HOXD9, TFAP2A	48	embryonic skeletal system morphogenesis
GO:0048705	4.753e-09	1.23	14 BARX2, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC8, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, TFAP2A	97	skeletal system morphogenesis
GO:0001501	1.171e-08	2.827	19 BARX2, HOXA10, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, TFAP2A	223	skeletal system development
GO:0003002	1.923e-08	2.244	17 CER1, HOXA10, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9	177	regionalization
GO:0007389	5.704e-07	2.865	17 CER1, HOXA10, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9	226	pattern specification process
GO:0032501	6.693e-07	41.83	74 AGR2, AGTR2, AQP2, ATP6V0A4, ATP6V1B1, BARX2, C6orf126, CALCA, CALCR, CDH3, CECR1, CER1, CLDN16, CLDN19, DMRT2, EDAR, EDN2, EGF, EHF, F2RL1, FOXI1, GHRHR, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, HSD11B2, IL18, INSRR, KCNJ1, KLK3, MMP1, MMP7, NPHS2, OLR1, PAX2, PAX8, PKHD1, POU2F3, PRR15, REN, RHCG, SCIN, SCNN1B, SCNN1G, SIM1, SIM2, SLC22A2, SLC34A1, SLC34A2, TACSTD2, TFAP2A, TFAP2B, TFCP2L1, TINAG, TSPAN8, USH1C, WFDC2, WNT9B	3300	multicellular organismal process
GO:0048562	2.025e-06	1.407	12 FOXI1, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXD10, HOXD3, HOXD4, HOXD9, TFAP2A	111	embryonic organ morphogenesis
GO:0006820	5.222e-06	0.9761	10 SLC10A2, SLC22A11, SLC22A12, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC4A1, WNK4	77	anion transport
GO:0006811	6.004e-06	8.405	27 AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, CALCA, CLDN16, EGF, FXYD2, KCNJ1, LTF, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC4A1, WNK4	663	ion transport
GO:0048598	8.073e-06	3.499	17 CER1, FOXI1, HOXA10, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXD10, HOXD3, HOXD4, HOXD9, TFAP2A, TINAG	276	embryonic morphogenesis
GO:0007588	1.302e-05	0.5958	8 AQP2, ATP6V0A4, ATP6V1B1, CLDN16, KCNJ1, NPHS2, SCNN1B, SCNN1G	47	excretion
GO:0009790	1.228e-04	6.44	21 CER1, FOXI1, HOXA10, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, SLC34A2, TFAP2A, TINAG	508	embryo development
GO:0048568	1.700e-04	2.218	12 FOXI1, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXD10, HOXD3, HOXD4, HOXD9, TFAP2A	175	embryonic organ development
GO:0006812	1.790e-04	6.06	20 AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, CALCA, EGF, FXYD2, KCNJ1, LTF, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A2, SLC34A1, SLC34A2, SLC34A3	478	cation transport
GO:0015672	2.905e-04	3.22	14 ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, FXYD2, KCNJ1, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC34A1, SLC34A2, SLC34A3	254	monovalent inorganic cation transport
GO:0030878	3.584e-04	0.1268	4 HOXA3, HOXA5, HOXD3, PAX8	10	thyroid gland development
GO:0009954	3.814e-04	0.2662	5 HOXA10, HOXC10, HOXC11, HOXD10, HOXD9	21	proximal/distal pattern formation
GO:0003073	4.421e-04	0.469	6 AGTR2, AQP2, CALCA, EDN2, HSD11B2, REN	37	regulation of systemic arterial blood pressure
GO:0032502	9.394e-04	32.91	55 AGTR2, AQP2, BARX2, CALCA, CALCR, CECR1, CER1, DMRT2, EDAR, EDN2, EGF, EHF, FOXI1, GATA3, GHRHR, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, IER3, IL18, INSRR, KLK3, PAX2, PAX8, PKHD1, POU2F3, PRR15, PTPRQ, REN, RHCG, SCIN, SIM1, SIM2, SLC34A2, TFAP2A, TFAP2B, TFCP2L1, TINAG, WNT9B	2596	developmental process
GO:0006814	1.025e-03	1.483	9 FXYD2, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC34A1, SLC34A2, SLC34A3	117	sodium ion transport
GO:0007275	1.715e-03	30.25	51 AGTR2, BARX2, CALCA, CALCR, CECR1, CER1, DMRT2, EDAR, EDN2, EGF, EHF, FOXI1, GHRHR, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, IL18, INSRR, KLK3, PAX2, PAX8, PKHD1, POU2F3, PRR15, REN, RHCG, SCIN, SIM1, SIM2, SLC34A2, TFAP2A, TFAP2B, TFCP2L1, TINAG, WNT9B	2386	multicellular organismal development
GO:0009653	1.903e-03	13.22	29 BARX2, CER1, EGF, FOXI1, GATA3, HOXA10, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC8, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, IER3, IL18, KLK3, PAX2, PAX8, PKHD1, TFAP2A, TFCP2L1, TINAG	1043	anatomical structure morphogenesis
GO:0016338	2.141e-03	0.2028	4 CLDN16, CLDN19, CLDN4, CLDN8	16	calcium-independent cell-cell adhesion
GO:0043009	2.373e-03	4.006	14 HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC6, HOXD1, HOXD10, HOXD3, HOXD4, HOXD9, SLC34A2, TFAP2A	316	chordate embryonic development
GO:0051252	2.410e-03	16.33	33 BARX2, CALCR, DMRT2, EHF, ESRP1, FOXI1, GATA3, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, PAX8, POU2F3, SIM1, SIM2, TFAP2A, TFAP2B, TFCP2L1	1288	regulation of RNA metabolic process
GO:0048856	2.421e-03	27.34	47 AGTR2, BARX2, CALCA, CALCR, CER1, DMRT2, EDAR, EDN2, EGF, EHF, FOXI1, GATA3, GHRHR, HOXA10, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, IER3, IL18, KLK3, PAX2, PAX8, PKHD1, POU2F3, REN, RHCG, SCIN, SIM1, SIM2, TFAP2A, TFAP2B, TFCP2L1, TINAG, WNT9B	2157	anatomical structure development
GO:0009792	2.581e-03	4.044	14 HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC6, HOXD1, HOXD10, HOXD3, HOXD4, HOXD9, SLC34A2, TFAP2A	319	embryo development ending in birth or egg hatching
GO:0048731	3.283e-03	25.25	44 AGTR2, BARX2, CALCA, CALCR, DMRT2, EDAR, EDN2, EGF, EHF, FOXI1, GHRHR, HOXA10, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, IL18, KLK3, PAX2, PAX8, PKHD1, POU2F3, REN, RHCG, SCIN, SIM1, SIM2, TFAP2A, TFAP2B, TFCP2L1, TINAG, WNT9B	1992	system development
GO:0042592	3.349e-03	8.291	21 AQP2, ATP6V0A4, ATP6V1B1, CALCA, CALCR, CCL19, CLDN16, EDN2, F2RL1, GHRHR, GYLTL1B, HOXA5, HOXB6, LTF, PKHD1, RHCG, SLC22A12, SLC34A1, SLC34A2, SLC34A3, SLC4A1	654	homeostatic process
GO:0015711	4.420e-03	0.469	5 SLC10A2, SLC22A11, SLC22A12, SLC22A6, SLC26A7	37	organic anion transport
GO:0001990	4.677e-03	0.2535	4 AGTR2, EDN2, HSD11B2, REN	20	regulation of systemic arterial blood pressure by hormone
GO:0055061	4.849e-03	0.1014	3 SLC34A1, SLC34A2, SLC34A3	8	di-, tri-valent inorganic anion homeostasis
GO:0055062	4.849e-03	0.1014	3 SLC34A1, SLC34A2, SLC34A3	8	phosphate ion homeostasis
GO:0006351	5.318e-03	17.13	33 BARX2, DMRT2, EHF, FOXI1, GATA3, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, PAX2, PAX8, POU2AF1, POU2F3, SIM1, SIM2, TFAP2A, TFAP2B, TFCP2L1	1351	transcription, DNA-dependent
GO:0032774	5.567e-03	17.18	33 BARX2, DMRT2, EHF, FOXI1, GATA3, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, PAX2, PAX8, POU2AF1, POU2F3, SIM1, SIM2, TFAP2A, TFAP2B, TFCP2L1	1355	RNA biosynthetic process
GO:0015698	6.039e-03	0.5071	5 SLC26A7, SLC34A1, SLC34A2, SLC34A3, WNK4	40	inorganic anion transport
GO:0006355	6.789e-03	15.88	31 BARX2, DMRT2, EHF, FOXI1, GATA3, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, PAX8, POU2F3, SIM1, SIM2, TFAP2A, TFAP2B, TFCP2L1	1253	regulation of transcription, DNA-dependent
GO:0050801	6.817e-03	4.513	14 ATP6V0A4, ATP6V1B1, CALCA, CALCR, CCL19, CLDN16, EDN2, F2RL1, LTF, RHCG, SLC34A1, SLC34A2, SLC34A3, SLC4A1	356	ion homeostasis
GO:0048513	8.253e-03	19.17	35 AGTR2, BARX2, CALCA, CALCR, DMRT2, EDAR, EDN2, EGF, EHF, FOXI1, GHRHR, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC11, HOXC8, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, IL18, KLK3, PAX2, PAX8, PKHD1, POU2F3, REN, RHCG, SCIN, TFAP2A, TFCP2L1	1512	organ development
GO:0006817	8.865e-03	0.1268	3 SLC34A1, SLC34A2, SLC34A3	10	phosphate transport
GO:0003044	9.779e-03	0.3169	4 AGTR2, EDN2, HSD11B2, REN	25	regulation of systemic arterial blood pressure mediated by a chemical signal
GO:0003071	1.127e-02	0.1394	3 AGTR2, AQP2, HSD11B2	11	renal system process involved in regulation of systemic arterial blood pressure
GO:0030855	1.183e-02	1.724	8 EHF, HOXA5, HOXA7, HOXB5, PAX2, POU2F3, RHCG, TFCP2L1	136	epithelial cell differentiation
GO:0009887	1.257e-02	6.693	17 BARX2, FOXI1, HOXA3, HOXA5, HOXA7, HOXB5, HOXB6, HOXB7, HOXC11, HOXC8, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, PAX2, TFAP2A	528	organ morphogenesis
GO:0055081	1.403e-02	0.1521	3 SLC34A1, SLC34A2, SLC34A3	12	anion homeostasis
GO:0016337	1.549e-02	3.296	11 BARX2, CALCA, CDH16, CDH17, CDH3, CLDN16, CLDN19, CLDN4, CLDN8, OLR1, PKHD1	260	cell-cell adhesion
GO:0046903	1.679e-02	5.045	14 AGR2, AQP2, ATP6V0A4, ATP6V1B1, CLDN16, EDN2, EGF, GHRHR, KCNJ1, NPHS2, SCIN, SCNN1B, SCNN1G, SLC22A2	398	secretion
GO:0048878	1.686e-02	5.654	15 ATP6V0A4, ATP6V1B1, CALCA, CALCR, CCL19, CLDN16, EDN2, F2RL1, GHRHR, LTF, RHCG, SLC34A1, SLC34A2, SLC34A3, SLC4A1	446	chemical homeostasis
GO:0050886	1.729e-02	0.3803	4 AGTR2, EDN2, HSD11B2, REN	30	endocrine process
GO:0008217	1.801e-02	1.027	6 AGTR2, AQP2, CALCA, EDN2, HSD11B2, REN	81	regulation of blood pressure
GO:0019725	1.854e-02	5.109	14 AQP2, CALCA, CALCR, CCL19, CLDN16, EDN2, F2RL1, GYLTL1B, LTF, RHCG, SLC22A12, SLC34A2, SLC34A3, SLC4A1	403	cellular homeostasis
GO:0030001	2.105e-02	5.198	14 AQP2, CALCA, EGF, FXYD2, KCNJ1, LTF, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC34A1, SLC34A2, SLC34A3	410	metal ion transport
GO:0048934	2.652e-02	0.05071	2 HOXD10, HOXD9	4	peripheral nervous system neuron differentiation
GO:0048935	2.652e-02	0.05071	2 HOXD10, HOXD9	4	peripheral nervous system neuron development
GO:0055080	3.142e-02	3.144	10 ATP6V0A4, ATP6V1B1, CALCA, CALCR, CCL19, CLDN16, EDN2, F2RL1, LTF, RHCG	248	cation homeostasis
GO:0035270	3.281e-02	0.8113	5 GHRHR, HOXA3, HOXA5, HOXD3, PAX8	64	endocrine system development
GO:0048732	3.353e-02	2.13	8 EGF, GHRHR, HOXA3, HOXA5, HOXD3, HOXD9, PAX8, TFCP2L1	168	gland development
GO:0021520	3.797e-02	0.06338	2 HOXC10, HOXD10	5	spinal cord motor neuron cell fate specification
GO:0065007	3.857e-02	65.97	83 AGR2, AGTR2, AQP2, ARHGEF38, ATP6V0A4, ATP6V1B1, BARX2, CALCA, CALCR, CCL19, CER1, CLDN16, DMRT2, DUSP9, EDAR, EDN2, EGF, EHF, ESRP1, F2RL1, FGFBP1, FOXI1, GATA3, GDF15, GHRHR, GPRC6A, GRHL2, GYLTL1B, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, HSD11B2, IER3, IL18, KLK3, KRT7, LTF, MACC1, MMP7, NUAK2, PAX2, PAX8, PKHD1, POU2AF1, POU2F3, PPP1R14D, PTPRQ, RAB25, RAB40A, REN, RHCG, SCIN, SCNN1B, SIM1, SIM2, SLC22A12, SLC22A2, SLC34A1, SLC34A2, SLC34A3, SLC4A1, TFAP2A, TFAP2B, TFCP2L1, TSPAN8, UMOD, WNK4	5204	biological regulation
GO:0009948	3.983e-02	0.2409	3 CER1, HOXB6, HOXD8	19	anterior/posterior axis specification

Id	Pvalue	ExpCount	Count	Size	Term
GO:0045177	1.142e-12	2.289	21 AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, EPCAM, MUC1, PKHD1, PROM2, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC34A2, SLC34A3, SLC4A9, UMOD, USH1C	170	apical part of cell
GO:0016324	1.942e-12	1.818	19 AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, EPCAM, MUC1, PKHD1, PROM2, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC34A2, SLC34A3, UMOD	135	apical plasma membrane
GO:0044459	1.094e-06	21.44	48 AGTR2, AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, BSND, CALCR, CDH17, CDH3, CLDN16, CLDN19, CLDN4, CLDN8, ECEL1, EPCAM, F2RL1, FERMT1, FXYD2, GPR172B, INSRR, KCNJ1, MUC1, NPHS2, OLR1, PKHD1, PROM2, PVRL4, RAB25, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC4A1, SLC4A9, SLC6A19, TACSTD2, UMOD, WNK4	1592	plasma membrane part
GO:0005886	3.207e-05	35.34	62 AGTR2, AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, BSND, CALCR, CDCP1, CDH16, CDH17, CDH3, CLDN16, CLDN19, CLDN4, CLDN8, ECEL1, EGF, EPCAM, F2RL1, FERMT1, FGFBP1, FXYD2, GHRHR, GP2, GPR110, GPR172B, GPRC6A, ILDR1, INSRR, KCNJ1, MUC1, NPHS2, OLR1, PKHD1, PROM2, PVRL4, RAB25, RAB40A, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC47A2, SLC4A1, SLC4A9, SLC6A19, SYT8, TAAR1, TACSTD2, UMOD, WNK4	2624	plasma membrane
GO:0016471	3.339e-05	0.09427	4 ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3	7	vacuolar proton-transporting V-type ATPase complex
GO:0016323	5.425e-05	2.586	13 AQP2, ATP6V1B1, BSND, CDH17, CLDN19, EPCAM, FERMT1, PROM2, RHCG, SLC22A6, SLC26A7, SLC4A1, SLC4A9	192	basolateral plasma membrane
GO:0031526	3.418e-04	0.3232	5 ATP6V0A4, SLC22A12, SLC34A1, SLC34A2, SLC34A3	24	brush border membrane
GO:0031253	6.530e-04	1.226	8 ATP6V0A4, FERMT1, PROM2, RAB25, SLC22A12, SLC34A1, SLC34A2, SLC34A3	91	cell projection membrane
GO:0033176	8.199e-04	0.202	4 ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3	15	proton-transporting V-type ATPase complex
GO:0031224	8.335e-04	50.06	74 AGTR2, APCDD1L, AQP2, ATP6V0A4, BSND, C12orf59, C9orf71, CA12, CALCR, CDCP1, CDH16, CDH17, CDH3, CLDN16, CLDN19, CLDN4, CLDN8, ECEL1, EDAR, EGF, EPCAM, F2RL1, FXYD2, GHRHR, GP2, GPR110, GPR172B, GPRC6A, GRAMD2, GYLTL1B, HEPACAM2, IER3, ILDR1, INSRR, KCNJ1, KLHDC7A, MS4A10, MUC1, NPHS2, OLR1, PDZK1IP1, PKHD1, PROM2, PTPRQ, PVRL4, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC44A4, SLC47A2, SLC4A1, SLC4A9, SLC6A19, SLC7A13, SYT8, TAAR1, TACSTD2, TMEM139, TMEM171, TMEM174, TSPAN1, TSPAN8, UMOD	3717	intrinsic to membrane
GO:0016021	1.357e-03	48.99	72 AGTR2, APCDD1L, AQP2, ATP6V0A4, BSND, C12orf59, C9orf71, CA12, CALCR, CDCP1, CDH16, CDH17, CDH3, CLDN16, CLDN19, CLDN4, CLDN8, ECEL1, EDAR, EGF, EPCAM, F2RL1, FXYD2, GHRHR, GPR110, GPR172B, GPRC6A, GRAMD2, GYLTL1B, HEPACAM2, IER3, ILDR1, INSRR, KCNJ1, KLHDC7A, MS4A10, MUC1, NPHS2, OLR1, PDZK1IP1, PKHD1, PROM2, PTPRQ, PVRL4, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC44A4, SLC47A2, SLC4A1, SLC4A9, SLC6A19, SLC7A13, SYT8, TAAR1, TACSTD2, TMEM139, TMEM171, TMEM174, TSPAN1, TSPAN8	3638	integral to membrane
GO:0044425	1.662e-03	57.73	81 AGTR2, AP1S3, APCDD1L, AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, BSND, C12orf59, C9orf71, CA12, CALCR, CDCP1, CDH16, CDH17, CDH3, CLDN16, CLDN19, CLDN4, CLDN8, ECEL1, EDAR, EGF, EPCAM, F2RL1, FERMT1, FXYD2, GHRHR, GP2, GPR110, GPR172B, GPRC6A, GRAMD2, GYLTL1B, HEPACAM2, IER3, ILDR1, INSRR, KCNJ1, KLHDC7A, MS4A10, MUC1, NPHS2, OLR1, PDZK1IP1, PKHD1, PROM2, PTPRQ, PVRL4, RAB25, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC44A4, SLC47A2, SLC4A1, SLC4A9, SLC6A19, SLC7A13, SYT8, TAAR1, TACSTD2, TMEM139, TMEM171, TMEM174, TSPAN1, TSPAN8, UMOD, WNK4	4287	membrane part
GO:0005903	2.065e-03	0.4848	5 ATP6V0A4, SLC22A12, SLC34A1, SLC34A2, SLC34A3	36	brush border
GO:0031226	5.362e-03	12.71	26 AGTR2, BSND, CALCR, CLDN4, ECEL1, F2RL1, FXYD2, GPR172B, INSRR, KCNJ1, MUC1, NPHS2, OLR1, PKHD1, RHCG, SCNN1G, SLC10A2, SLC12A3, SLC22A11, SLC22A2, SLC22A6, SLC34A1, SLC34A2, SLC4A1, SLC6A19, TACSTD2	944	intrinsic to plasma membrane
GO:0005774	6.754e-03	1.374	7 ACPP, ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, PLA2G4F, TSPAN1	102	vacuolar membrane
GO:0005887	8.543e-03	12.44	25 AGTR2, BSND, CALCR, CLDN4, ECEL1, F2RL1, FXYD2, GPR172B, INSRR, KCNJ1, MUC1, NPHS2, OLR1, RHCG, SCNN1G, SLC10A2, SLC12A3, SLC22A11, SLC22A2, SLC22A6, SLC34A1, SLC34A2, SLC4A1, SLC6A19, TACSTD2	924	integral to plasma membrane
GO:0044437	9.061e-03	1.454	7 ACPP, ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, PLA2G4F, TSPAN1	108	vacuolar part
GO:0016469	1.050e-02	0.4175	4 ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3	31	proton-transporting two-sector ATPase complex
GO:0005923	1.153e-02	0.7407	5 CLDN16, CLDN19, CLDN4, CLDN8, WNK4	55	tight junction
GO:0070160	1.153e-02	0.7407	5 CLDN16, CLDN19, CLDN4, CLDN8, WNK4	55	occluding junction
GO:0043296	2.153e-02	0.8754	5 CLDN16, CLDN19, CLDN4, CLDN8, WNK4	65	apical junction complex
GO:0016327	2.545e-02	0.9158	5 CLDN16, CLDN19, CLDN4, CLDN8, WNK4	68	apicolateral plasma membrane
GO:0016020	2.961e-02	69.33	87 ACPP, AGTR2, AP1S3, APCDD1L, AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, BSND, C12orf59, C9orf71, CA12, CALCR, CDCP1, CDH16, CDH17, CDH3, CLDN16, CLDN19, CLDN4, CLDN8, ECEL1, EDAR, EGF, EPCAM, F2RL1, FERMT1, FGFBP1, FXYD2, GHRHR, GP2, GPR110, GPR172B, GPRC6A, GRAMD2, GYLTL1B, HEPACAM2, IER3, ILDR1, INSRR, KCNJ1, KLHDC7A, MS4A10, MUC1, NPHS2, OLR1, PDZK1IP1, PKHD1, PLA2G4F, PROM2, PTPRQ, PVRL4, RAB25, RAB40A, REN, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC44A4, SLC47A2, SLC4A1, SLC4A9, SLC6A19, SLC7A13, SYT8, TAAR1, TACSTD2, TFCP2L1, TMEM139, TMEM171, TMEM174, TSPAN1, TSPAN8, UMOD, WNK4	5148	membrane
GO:0005773	3.379e-02	2.99	9 ACPP, AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, PLA2G4F, TSPAN1, TSPAN8	222	vacuole

Id	Pvalue	ExpCount	Count	Size	Term
GO:0043565	1.883e-09	5.674	27 BARX2, EHF, FOXI1, GATA3, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, PAX2, PAX8, POU2F3, TFAP2B	460	sequence-specific DNA binding
GO:0003700	1.268e-08	8.734	32 BARX2, DMRT2, EHF, FOXI1, GATA3, GRHL2, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, PAX8, POU2F3, SIM1, SIM2, TFAP2A, TFAP2B, TFCP2L1	708	sequence-specific DNA binding transcription factor activity
GO:0022857	2.237e-07	8.783	30 AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, BSND, CDH17, CLDN16, FXYD2, GPR172B, KCNJ1, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC47A2, SLC4A1, SLC4A9, SLC6A19, SLC7A13	712	transmembrane transporter activity
GO:0022804	8.462e-07	3.417	18 ATP6V0A4, ATP6V1B1, CDH17, FXYD2, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC47A2, SLC4A1, SLC4A9, SLC6A19, SLC7A13	277	active transmembrane transporter activity
GO:0015291	1.022e-06	1.974	14 CDH17, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC47A2, SLC4A1, SLC4A9, SLC6A19	160	secondary active transmembrane transporter activity
GO:0022891	6.845e-06	8.006	26 AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, BSND, CLDN16, FXYD2, KCNJ1, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC4A1, SLC4A9, SLC6A19, SLC7A13	649	substrate-specific transmembrane transporter activity
GO:0022892	9.399e-06	9.301	28 AP1S3, AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, BSND, CDH17, CLDN16, FXYD2, KCNJ1, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC4A1, SLC4A9, SLC6A19, SLC7A13	754	substrate-specific transporter activity
GO:0005215	1.216e-05	11.25	31 AP1S3, AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, BSND, CDH17, CLDN16, FXYD2, GPR172B, KCNJ1, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC47A2, SLC4A1, SLC4A9, SLC6A19, SLC7A13	912	transporter activity
GO:0008509	1.680e-05	1.456	11 BSND, SLC12A1, SLC12A3, SLC22A11, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC4A1, SLC4A9	118	anion transmembrane transporter activity
GO:0015075	2.791e-05	6.97	23 ATP6V0A4, ATP6V0D2, ATP6V1B1, BSND, CLDN16, FXYD2, KCNJ1, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A2, SLC22A6, SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC4A1, SLC4A9, SLC6A19	565	ion transmembrane transporter activity
GO:0015380	7.129e-05	0.1974	5 SLC22A11, SLC22A6, SLC26A7, SLC4A1, SLC4A9	16	anion exchanger activity
GO:0015301	9.603e-05	0.2097	5 SLC22A11, SLC22A6, SLC26A7, SLC4A1, SLC4A9	17	anion:anion antiporter activity
GO:0005452	5.224e-04	0.148	4 SLC22A11, SLC22A6, SLC4A1, SLC4A9	12	inorganic anion exchanger activity
GO:0015321	8.633e-04	0.06168	3 SLC34A1, SLC34A2, SLC34A3	5	sodium-dependent phosphate transmembrane transporter activity
GO:0015103	1.526e-03	0.3824	5 SLC26A7, SLC34A1, SLC34A2, SLC34A3, SLC4A1	31	inorganic anion transmembrane transporter activity
GO:0022890	1.574e-03	2.035	10 ATP6V0A4, ATP6V0D2, ATP6V1B1, CLDN16, FXYD2, RHCG, SLC10A2, SLC34A2, SLC34A3, SLC6A19	165	inorganic cation transmembrane transporter activity
GO:0015297	2.081e-03	0.6661	6 SLC22A11, SLC22A6, SLC26A7, SLC47A2, SLC4A1, SLC4A9	54	antiporter activity
GO:0008324	3.492e-03	5.391	16 ATP6V0A4, ATP6V0D2, ATP6V1B1, CLDN16, FXYD2, KCNJ1, RHCG, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A2, SLC34A2, SLC34A3, SLC6A19	437	cation transmembrane transporter activity
GO:0015300	5.398e-03	0.5181	5 SLC22A11, SLC22A6, SLC26A7, SLC4A1, SLC4A9	42	solute:solute antiporter activity
GO:0015077	5.548e-03	1.554	8 ATP6V0A4, ATP6V0D2, ATP6V1B1, FXYD2, SLC10A2, SLC34A2, SLC34A3, SLC6A19	126	monovalent inorganic cation transmembrane transporter activity
GO:0015294	8.440e-03	0.9005	6 SLC10A2, SLC12A1, SLC12A3, SLC34A2, SLC34A3, SLC6A19	73	solute:cation symporter activity
GO:0015293	1.029e-02	1.32	7 SLC10A2, SLC12A1, SLC12A3, SLC34A1, SLC34A2, SLC34A3, SLC6A19	107	symporter activity
GO:0003677	1.194e-02	16.7	31 BARX2, EHF, FOXI1, GATA3, HOXA10, HOXA3, HOXA5, HOXA7, HOXA9, HOXB5, HOXB6, HOXB7, HOXC10, HOXC11, HOXC6, HOXC8, HOXC9, HOXD1, HOXD10, HOXD3, HOXD4, HOXD8, HOXD9, PAX2, PAX8, POU2AF1, POU2F3, SIM1, SIM2, TFAP2A, TFAP2B	1354	DNA binding
GO:0015296	1.325e-02	0.3701	4 SLC12A1, SLC12A3, SLC34A2, SLC34A3	30	anion:cation symporter activity
GO:0015114	1.337e-02	0.1604	3 SLC34A1, SLC34A2, SLC34A3	13	phosphate transmembrane transporter activity
GO:0015081	2.848e-02	0.8141	5 FXYD2, SLC10A2, SLC34A2, SLC34A3, SLC6A19	66	sodium ion transmembrane transporter activity
GO:0015347	3.118e-02	0.06168	2 SLC22A11, SLC22A6	5	sodium-independent organic anion transmembrane transporter activity
GO:0005342	3.623e-02	0.8758	5 SLC10A2, SLC22A12, SLC26A7, SLC6A19, SLC7A13	71	organic acid transmembrane transporter activity

Id	Pvalue	ExpCount	Count	Size	Term
04966	1.330e-04	0.2409	5 ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3, SLC4A1	21	Collecting duct acid secretion
04960	1.053e-03	0.3785	5 FXYD2, HSD11B2, KCNJ1, SCNN1B, SCNN1G	33	Aldosterone-regulated sodium reabsorption
05110	2.070e-02	0.4588	4 ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3	40	Vibrio cholerae infection
05120	4.853e-02	0.6079	4 ATP6V0A4, ATP6V0D2, ATP6V1B1, ATP6V1G3	53	Epithelial cell signaling in Helicobacter pylori infection

No enriched terms

No enriched terms

Entrez genes

ACPPacid phosphatase, prostate (ENSG00000014257), score: 0.58 AGR2anterior gradient homolog 2 (Xenopus laevis) (ENSG00000106541), score: 0.76 AGTR2angiotensin II receptor, type 2 (ENSG00000180772), score: 0.56 AP1S3adaptor-related protein complex 1, sigma 3 subunit (ENSG00000152056), score: 0.7 APCDD1Ladenomatosis polyposis coli down-regulated 1-like (ENSG00000198768), score: 0.69 AQP2aquaporin 2 (collecting duct) (ENSG00000167580), score: 0.61 ARHGEF38Rho guanine nucleotide exchange factor (GEF) 38 (ENSG00000138784), score: 0.97 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.61 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.57 ATP6V1B1ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 (ENSG00000116039), score: 0.59 ATP6V1G3ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 (ENSG00000151418), score: 0.65 BARX2BARX homeobox 2 (ENSG00000043039), score: 0.58 BSNDBartter syndrome, infantile, with sensorineural deafness (Barttin) (ENSG00000162399), score: 0.65 C12orf59chromosome 12 open reading frame 59 (ENSG00000165685), score: 0.58 C17orf99chromosome 17 open reading frame 99 (ENSG00000187997), score: 0.84 C19orf21chromosome 19 open reading frame 21 (ENSG00000099812), score: 0.6 C6orf126chromosome 6 open reading frame 126 (ENSG00000196748), score: 0.65 C9orf71chromosome 9 open reading frame 71 (ENSG00000181778), score: 0.65 C9orf84chromosome 9 open reading frame 84 (ENSG00000165181), score: 0.72 CA12carbonic anhydrase XII (ENSG00000074410), score: 0.56 CALCAcalcitonin-related polypeptide alpha (ENSG00000110680), score: 0.59 CALCRcalcitonin receptor (ENSG00000004948), score: 0.64 CCDC153coiled-coil domain containing 153 (ENSG00000204313), score: 0.57 CCDC64Bcoiled-coil domain containing 64B (ENSG00000162069), score: 0.64 CCL19chemokine (C-C motif) ligand 19 (ENSG00000172724), score: 0.58 CDCP1CUB domain containing protein 1 (ENSG00000163814), score: 0.75 CDH16cadherin 16, KSP-cadherin (ENSG00000166589), score: 0.62 CDH17cadherin 17, LI cadherin (liver-intestine) (ENSG00000079112), score: 0.82 CDH3cadherin 3, type 1, P-cadherin (placental) (ENSG00000062038), score: 0.59 CECR1cat eye syndrome chromosome region, candidate 1 (ENSG00000093072), score: 0.62 CER1cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis) (ENSG00000147869), score: 0.57 CLDN16claudin 16 (ENSG00000113946), score: 0.62 CLDN19claudin 19 (ENSG00000164007), score: 0.59 CLDN4claudin 4 (ENSG00000189143), score: 0.62 CLDN8claudin 8 (ENSG00000156284), score: 0.61 DHDHdihydrodiol dehydrogenase (dimeric) (ENSG00000104808), score: 0.64 DMRT2doublesex and mab-3 related transcription factor 2 (ENSG00000173253), score: 0.59 DUSP9dual specificity phosphatase 9 (ENSG00000130829), score: 0.61 ECEL1endothelin converting enzyme-like 1 (ENSG00000171551), score: 0.73 EDARectodysplasin A receptor (ENSG00000135960), score: 0.7 EDN2endothelin 2 (ENSG00000127129), score: 0.68 EGFepidermal growth factor (ENSG00000138798), score: 0.57 EHFets homologous factor (ENSG00000135373), score: 0.63 ENOSF1enolase superfamily member 1 (ENSG00000132199), score: 0.57 EPCAMepithelial cell adhesion molecule (ENSG00000119888), score: 0.57 EPS8L1EPS8-like 1 (ENSG00000131037), score: 0.75 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.63 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.59 FERMT1fermitin family member 1 (ENSG00000101311), score: 0.69 FGFBP1fibroblast growth factor binding protein 1 (ENSG00000137440), score: 0.7 FOXI1forkhead box I1 (ENSG00000168269), score: 0.59 FRMD1FERM domain containing 1 (ENSG00000153303), score: 0.61 FXYD2FXYD domain containing ion transport regulator 2 (ENSG00000137731), score: 0.57 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.65 GDF15growth differentiation factor 15 (ENSG00000130513), score: 0.56 GHRHRgrowth hormone releasing hormone receptor (ENSG00000106128), score: 0.65 GP2glycoprotein 2 (zymogen granule membrane) (ENSG00000169347), score: 0.57 GPR110G protein-coupled receptor 110 (ENSG00000153292), score: 0.58 GPR172BG protein-coupled receptor 172B (ENSG00000132517), score: 0.63 GPRC6AG protein-coupled receptor, family C, group 6, member A (ENSG00000173612), score: 0.56 GRAMD2GRAM domain containing 2 (ENSG00000175318), score: 0.59 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.63 GYLTL1Bglycosyltransferase-like 1B (ENSG00000165905), score: 0.57 HEPACAM2HEPACAM family member 2 (ENSG00000188175), score: 0.65 HOXA10homeobox A10 (ENSG00000153807), score: 0.7 HOXA3homeobox A3 (ENSG00000105997), score: 0.6 HOXA5homeobox A5 (ENSG00000106004), score: 0.66 HOXA7homeobox A7 (ENSG00000122592), score: 0.57 HOXA9homeobox A9 (ENSG00000078399), score: 0.7 HOXB5homeobox B5 (ENSG00000120075), score: 0.71 HOXB6homeobox B6 (ENSG00000108511), score: 0.61 HOXB7homeobox B7 (ENSG00000120087), score: 0.68 HOXC10homeobox C10 (ENSG00000180818), score: 0.62 HOXC11homeobox C11 (ENSG00000123388), score: 0.78 HOXC6homeobox C6 (ENSG00000197757), score: 0.66 HOXC8homeobox C8 (ENSG00000037965), score: 0.72 HOXC9homeobox C9 (ENSG00000180806), score: 0.64 HOXD1homeobox D1 (ENSG00000128645), score: 0.58 HOXD10homeobox D10 (ENSG00000128710), score: 0.64 HOXD3homeobox D3 (ENSG00000128652), score: 0.69 HOXD4homeobox D4 (ENSG00000170166), score: 0.62 HOXD8homeobox D8 (ENSG00000175879), score: 0.58 HOXD9homeobox D9 (ENSG00000128709), score: 0.66 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.58 IER3immediate early response 3 (ENSG00000137331), score: 0.58 IL18interleukin 18 (interferon-gamma-inducing factor) (ENSG00000150782), score: 0.56 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.63 INSRRinsulin receptor-related receptor (ENSG00000027644), score: 0.57 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.63 KLHDC7Akelch domain containing 7A (ENSG00000179023), score: 0.61 KLK3kallikrein-related peptidase 3 (ENSG00000142515), score: 1 KRT7keratin 7 (ENSG00000135480), score: 0.6 LTFlactotransferrin (ENSG00000012223), score: 0.59 MACC1metastasis associated in colon cancer 1 (ENSG00000183742), score: 0.71 MIOXmyo-inositol oxygenase (ENSG00000100253), score: 0.59 MMP1matrix metallopeptidase 1 (interstitial collagenase) (ENSG00000196611), score: 0.85 MMP7matrix metallopeptidase 7 (matrilysin, uterine) (ENSG00000137673), score: 0.71 MS4A10membrane-spanning 4-domains, subfamily A, member 10 (ENSG00000172689), score: 0.57 MUC1mucin 1, cell surface associated (ENSG00000185499), score: 0.58 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 0.64 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.57 OLR1oxidized low density lipoprotein (lectin-like) receptor 1 (ENSG00000173391), score: 0.58 PAX2paired box 2 (ENSG00000075891), score: 0.56 PAX8paired box 8 (ENSG00000125618), score: 0.62 PDZK1IP1PDZK1 interacting protein 1 (ENSG00000162366), score: 0.57 PKHD1polycystic kidney and hepatic disease 1 (autosomal recessive) (ENSG00000170927), score: 0.6 PLA2G4Fphospholipase A2, group IVF (ENSG00000168907), score: 0.63 POU2AF1POU class 2 associating factor 1 (ENSG00000110777), score: 0.59 POU2F3POU class 2 homeobox 3 (ENSG00000137709), score: 0.69 PPP1R14Dprotein phosphatase 1, regulatory (inhibitor) subunit 14D (ENSG00000166143), score: 0.73 PROM2prominin 2 (ENSG00000155066), score: 0.66 PRR15proline rich 15 (ENSG00000176532), score: 0.67 PRR15Lproline rich 15-like (ENSG00000167183), score: 0.59 PTPRQprotein tyrosine phosphatase, receptor type, Q (ENSG00000139304), score: 0.63 PVRL4poliovirus receptor-related 4 (ENSG00000143217), score: 0.56 R3HDMLR3H domain containing-like (ENSG00000101074), score: 0.57 RAB25RAB25, member RAS oncogene family (ENSG00000132698), score: 0.63 RAB40ARAB40A, member RAS oncogene family (ENSG00000172476), score: 0.6 RENrenin (ENSG00000143839), score: 0.58 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.56 SCGB2A1secretoglobin, family 2A, member 1 (ENSG00000124939), score: 0.7 SCINscinderin (ENSG00000006747), score: 0.58 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.59 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.59 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.64 SIM2single-minded homolog 2 (Drosophila) (ENSG00000159263), score: 0.58 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.57 SLC12A1solute carrier family 12 (sodium/potassium/chloride transporters), member 1 (ENSG00000074803), score: 0.61 SLC12A3solute carrier family 12 (sodium/chloride transporters), member 3 (ENSG00000070915), score: 0.56 SLC22A11solute carrier family 22 (organic anion/urate transporter), member 11 (ENSG00000168065), score: 0.6 SLC22A12solute carrier family 22 (organic anion/urate transporter), member 12 (ENSG00000197891), score: 0.61 SLC22A2solute carrier family 22 (organic cation transporter), member 2 (ENSG00000112499), score: 0.57 SLC22A6solute carrier family 22 (organic anion transporter), member 6 (ENSG00000197901), score: 0.57 SLC26A7solute carrier family 26, member 7 (ENSG00000147606), score: 0.56 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.61 SLC34A2solute carrier family 34 (sodium phosphate), member 2 (ENSG00000157765), score: 0.64 SLC34A3solute carrier family 34 (sodium phosphate), member 3 (ENSG00000198569), score: 0.7 SLC44A4solute carrier family 44, member 4 (ENSG00000204385), score: 0.61 SLC47A2solute carrier family 47, member 2 (ENSG00000180638), score: 0.59 SLC4A1solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (ENSG00000004939), score: 0.58 SLC4A9solute carrier family 4, sodium bicarbonate cotransporter, member 9 (ENSG00000113073), score: 0.59 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.58 SLC7A13solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 (ENSG00000164893), score: 0.6 SULT1C2sulfotransferase family, cytosolic, 1C, member 2 (ENSG00000198203), score: 0.57 SYT8synaptotagmin VIII (ENSG00000149043), score: 0.58 TAAR1trace amine associated receptor 1 (ENSG00000146399), score: 0.66 TACSTD2tumor-associated calcium signal transducer 2 (ENSG00000184292), score: 0.61 TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (ENSG00000137203), score: 0.55 TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta) (ENSG00000008196), score: 0.6 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.56 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.61 TMEM139transmembrane protein 139 (ENSG00000178826), score: 0.61 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.58 TMEM174transmembrane protein 174 (ENSG00000164325), score: 0.62 TSPAN1tetraspanin 1 (ENSG00000117472), score: 0.56 TSPAN8tetraspanin 8 (ENSG00000127324), score: 0.56 UMODuromodulin (ENSG00000169344), score: 0.68 USH1CUsher syndrome 1C (autosomal recessive, severe) (ENSG00000006611), score: 0.6 WFDC2WAP four-disulfide core domain 2 (ENSG00000101443), score: 0.58 WNK4WNK lysine deficient protein kinase 4 (ENSG00000126562), score: 0.68 WNT9Bwingless-type MMTV integration site family, member 9B (ENSG00000158955), score: 0.56

Non-Entrez genes

ENSG00000157111Unknown, score: 0.83 ENSG00000187997Unknown, score: 0.65 ENSG00000127129Unknown, score: 0.58 ENSG00000163814Unknown, score: 0.56

Id	species	tissue	sex	individual
ppa_kd_m_ca1	ppa	kd	m	_
ppa_kd_f_ca1	ppa	kd	f	_
ppy_kd_m_ca1	ppy	kd	m	_
ppy_kd_f_ca1	ppy	kd	f	_