Difference between revisions of "Narcolepsy"

 
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'''Narcolepsy Project'''
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[[Category:Bulletins]]
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<newstitle>Genome-wide Association Study reveals new HLA-haplotype strongly protective against narcolepsy</newstitle>
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    <teaser>
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In collaboration with Mehdi Tafti's research group we have published our recent discovery on a newly identified HLA haplotype that protects individuals from narcolepsy even if they carry the famous risk haplotype. Our article appeared online in <a href="http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html">Nature Genetics</a> on 15 August 2010.
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    <date>16 Aug 2010 — 11:45</date>
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    </teaser>
  
We are involved in a Genome-wide Association Study on narcolepsy conducted by [http://www.unil.ch/cig/page8695_en.html Mehdi Tafti]'s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in [http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics].
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We are involved in a [[Genome Wide Association Studies | Genome-wide Association Study]] on narcolepsy conducted by [http://www.unil.ch/cig/page8695_en.html Mehdi Tafti]'s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in [http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics].
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<pubmed>
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20711174
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</pubmed>

Latest revision as of 17:07, 20 August 2012



We are involved in a Genome-wide Association Study on narcolepsy conducted by Mehdi Tafti's Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in Nature Genetics.