Difference between revisions of "Narcolepsy"
(12 intermediate revisions by 2 users not shown) | |||
Line 1: | Line 1: | ||
− | ' | + | [[Category:Bulletins]] |
+ | <newstitle>Genome-wide Association Study reveals new HLA-haplotype strongly protective against narcolepsy</newstitle> | ||
+ | <teaser> | ||
+ | In collaboration with Mehdi Tafti's research group we have published our recent discovery on a newly identified HLA haplotype that protects individuals from narcolepsy even if they carry the famous risk haplotype. Our article appeared online in <a href="http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html">Nature Genetics</a> on 15 August 2010. | ||
+ | <date>16 Aug 2010 — 11:45</date> | ||
+ | </teaser> | ||
− | We are involved in a Genome-wide Association Study on narcolepsy conducted by [http://www.unil.ch/cig/page8695_en.html Mehdi Tafti]'s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in [http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics]. | + | We are involved in a [[Genome Wide Association Studies | Genome-wide Association Study]] on narcolepsy conducted by [http://www.unil.ch/cig/page8695_en.html Mehdi Tafti]'s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in [http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics]. |
+ | |||
+ | <pubmed> | ||
+ | 20711174 | ||
+ | </pubmed> |
Latest revision as of 17:07, 20 August 2012
We are involved in a Genome-wide Association Study on narcolepsy conducted by Mehdi Tafti's Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in Nature Genetics.