Control of mitosis in fission yeast

Background: Fission yeast cells growth up to a given size and then enters mitosis. The question this project addresses is how does the cell knows it has reached to right size for division. This is achieved by a gradient of the pom1 protein along the cortex.

Goal: The goal is to mathematically describe the mechanism by which such a gradient is achieved using differential equation and analyze such gradients from fluorescence microscopy images.

Mathematical tools: Ordinary differential equations, Mathematica, Matlab, ImageJ

Biological or Medical aspects: Size regulation in the fission yeast

Supervisor: Sascha Dalessi

Students: Degrugillier Lucas, Delapierre Fabien, Merçay Johan.

Presentation:

References: <biblio>

  1. hachet10 pmid=21703453

</biblio> <a href="http://cshperspectives.cshlp.org/content/1/3/a001255.full.pdf+html">Morpho </a>

Back to UNIL BSc course: "Solving Biological Problems that require Math 2012"]