Difference between revisions of "Narcolepsy"

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'''Narcolepsy Project'''
 
'''Narcolepsy Project'''
  
We are involved in a Genome-wide Association Study on narcolepsy conducted by [[http://www.unil.ch/cig/page8695_en.html Mehdi Tafti]]'s Group at the University of Lausanne.
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We are involved in a Genome-wide Association Study on narcolepsy conducted by [http://www.unil.ch/cig/page8695_en.html Mehdi Tafti]'s Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in [http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics].
 
 
The research findings were published in [[http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.647.html Nature Genetics]].
 

Revision as of 11:40, 16 August 2010

Narcolepsy Project

We are involved in a Genome-wide Association Study on narcolepsy conducted by Mehdi Tafti's Group at the University of Lausanne. In brief, we identified a haplotype in the HLA-region that is strongly protective against narcolepsy. More than 10% of HLA-positive controls carry this DRB1*1301-DQB1*0603 haplotype, which was found in virtually no narcoleptic cases. The research findings were published in Nature Genetics.