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system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell surface receptor linked signal transduction

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

G-protein coupled receptor protein signaling pathway

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

sensory perception

The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cognition

The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell fraction

A generic term for parts of cells prepared by disruptive biochemical techniques.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

insoluble fraction

That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

nucleotide receptor activity, G-protein coupled

A GPCR that binds a nucleotide or nucleotide derivative as its ligand.

purinergic nucleotide receptor activity

Combining with a purine nucleotide to initiate a change in cell activity.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

G-protein coupled receptor activity

A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

metal ion binding

Interacting selectively with any metal ion.

iron ion binding

Interacting selectively with iron (Fe) ions.

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

oxygen binding

Interacting selectively with oxygen (O2).

nucleotide receptor activity

Combining with a nucleotide to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.

heme binding

Interacting selectively with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

neurotransmitter binding

Interacting selectively with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.

ion binding

Interacting selectively with ions, charged atoms or groups of atoms.

cation binding

Interacting selectively with cations, charged atoms or groups of atoms with a net positive charge.

purinergic nucleotide receptor activity, G-protein coupled

Combining with a purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.

tetrapyrrole binding

Interacting selectively with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.

transition metal ion binding

Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.

transition metal ion binding

Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

heme binding

Interacting selectively with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

purinergic nucleotide receptor activity, G-protein coupled

Combining with a purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0032501	3.320e-09	78.8	134 ABCG1, ACRV1, ADAMTS9, ADORA1, ADORA2A, ADRA1D, AIPL1, AKIRIN2, AKR1D1, ALMS1, BAIAP3, BCL2L11, BMP10, BRS3, CA4, CAPN9, CATSPER2, CD28, CEACAM1, CHRNA6, COL11A2, COX5B, CSF2RB, CSPG5, CTSE, CXCL10, CYLC1, CYP11B1, CYP1A2, DAZ1, DAZ3, DAZ4, DES, DIP2A, DLX4, DRD5, EDAR, ERBB3, ERBB4, F11, FABP7, FCER1A, FCER1G, FOXC1, FZD3, GABRR1, GATA3, GLRA1, GNAO1, GNRHR, GP6, GRM6, HAND1, HBB, HOXD4, HTN1, HTR1E, HTR1F, IFNG, IL12B, IL1RAPL1, INSR, ISL1, KALRN, KCNMB4, KERA, KLF1, KNG1, KRT2, LHX3, LY6H, MB, MCL1, MEP1B, MFNG, MOBP, MOG, MYBPC1, MYH15, MYL4, MYO1A, NHLH2, NOTCH4, NTNG1, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, OVOL2, PAX4, PBX2, PGC, PGF, PHC3, POGZ, POU4F1, PPARGC1A, PROX1, RET, RPGRIP1, RRH, RYR3, SCN10A, SEMA6D, SERF1B, SFN, SFTPB, SH3GL3, SHOX2, SLC15A1, SLC17A6, SLC1A2, SLC26A4, SPN, SPRY1, SYN2, TAC1, TAS2R16, TAS2R9, TBX21, TBX6, TIMM8A, TLR1, TP63, TRPV1, TSPY1, TULP2, UTF1, VGF, XRCC2, ZIC1, ZNF160, ZNF287	1611	multicellular organismal process
GO:0003008	2.598e-07	21.77	53 ADORA2A, ADRA1D, AIPL1, ALMS1, BAIAP3, BMP10, BRS3, CA4, CHRNA6, COL11A2, CXCL10, CYP11B1, DES, DRD5, FOXC1, GABRR1, GATA3, GLRA1, GNAO1, GRM6, HBB, HTR1E, HTR1F, IFNG, IL12B, IL1RAPL1, KCNMB4, KERA, KNG1, MYBPC1, MYH15, MYL4, MYO1A, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, RYR3, SCN10A, SLC17A6, SLC1A2, SLC26A4, SYN2, TAC1, TAS2R16, TAS2R9, TIMM8A, TRPV1, TULP2	445	system process
GO:0007186	5.657e-06	11.3	33 ADORA1, ADORA2A, ADRA1D, BRS3, CCR9, DRD5, FZD3, GABRR1, GLRA1, GNAO1, GNG4, GNRHR, GPR12, GPR32, GRM6, HTR1E, HTR1F, INSR, LPAR4, NPY2R, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, RAPGEF4, RRH, TAAR2, TAC1, TACR1, TAS2R16, TAS2R9, TSHB	231	G-protein coupled receptor protein signaling pathway
GO:0050877	6.116e-06	15.51	40 ADORA2A, ADRA1D, AIPL1, ALMS1, BAIAP3, CA4, CHRNA6, COL11A2, DRD5, GABRR1, GATA3, GLRA1, GRM6, HTR1E, HTR1F, IFNG, IL12B, IL1RAPL1, KCNMB4, KERA, MYO1A, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, SCN10A, SLC17A6, SLC1A2, SLC26A4, SYN2, TAC1, TAS2R16, TAS2R9, TIMM8A, TRPV1, TULP2	317	neurological system process
GO:0007600	4.500e-05	8.365	26 ADORA2A, AIPL1, ALMS1, CA4, COL11A2, GATA3, GLRA1, GRM6, IL12B, KERA, MYO1A, OR2B2, OR2C1, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, SCN10A, SLC26A4, TAC1, TAS2R16, TAS2R9, TIMM8A, TRPV1, TULP2	171	sensory perception
GO:0007166	1.662e-04	33.41	62 ADORA1, ADORA2A, ADRA1D, BCL9, BMP10, BRS3, CCR9, CD28, CDKN1C, CEACAM1, CSF2RB, CXCL10, DRD5, DTX4, ERBB3, ERBB4, FCER1A, FCER1G, FGFR2, FOXC1, FZD3, GAB1, GABRR1, GLRA1, GNAO1, GNG4, GNRHR, GP6, GPR12, GPR32, GRM6, HTR1E, HTR1F, IFNG, IL12B, IL2RB, INSR, LAT2, LPAR4, MAGI1, NOTCH4, NPY2R, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, RAPGEF4, ROS1, RRH, SIRPB1, SPN, TAAR2, TAC1, TACR1, TAS2R16, TAS2R9, TP63, TRPV1, TSHB, WNT6	683	cell surface receptor linked signal transduction
GO:0050890	3.202e-04	9.93	27 ADORA2A, AIPL1, ALMS1, CA4, COL11A2, GATA3, GLRA1, GRM6, IL12B, IL1RAPL1, KERA, MYO1A, OR2B2, OR2C1, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, SCN10A, SLC26A4, TAC1, TAS2R16, TAS2R9, TIMM8A, TRPV1, TULP2	203	cognition
GO:0006952	4.385e-04	12.57	31 ADORA1, ADORA2A, AKIRIN2, CCR9, CD28, CHST4, CR1, CXCL10, CYBB, FCER1A, FCER1G, GATA3, HAMP, HTN1, IFNA16, IFNA5, IFNG, IL12B, IL1RAPL1, ITK, KNG1, MASP2, MEFV, PGLYRP4, PLA2G7, PLUNC, SP140, SPN, TAC1, TACR1, TLR1	257	defense response
GO:0007586	1.557e-02	1.272	7 AKR1D1, CAPN9, CTSE, MEP1B, PGC, PPARGC1A, SLC15A1	26	digestion
GO:0042108	1.687e-02	0.9294	6 CD28, FCER1A, IFNG, IL12B, SPN, TLR1	19	positive regulation of cytokine biosynthetic process
GO:0006805	1.967e-02	0.6359	5 CYP1A2, HAMP, HTN1, PON1, UGT2B28	13	xenobiotic metabolic process
GO:0007165	2.059e-02	86.48	115 ACOT11, ADCY2, ADORA1, ADORA2A, ADRA1D, APBB2, ARAP2, BCL2L11, BCL9, BMP10, BRS3, CCR9, CD28, CD53, CDKN1C, CEACAM1, CEACAM6, CHN2, CHRNA6, CLEC4M, CNKSR2, CSF2RB, CXCL10, DAPP1, DNASE1L3, DRD5, DTX4, EDAR, EEF1D, EPAG, ERBB3, ERBB4, FCER1A, FCER1G, FGD2, FGD6, FGFR2, FGL1, FOXC1, FZD3, G3BP1, GAB1, GABRR1, GLRA1, GNAO1, GNG4, GNRHR, GP6, GPR12, GPR32, GRM6, HLA-DRB4, HTR1E, HTR1F, IFNG, IL12B, IL1RAPL1, IL2RB, INSR, ITK, KALRN, LAT2, LAX1, LILRB4, LPAR4, LRRN2, MAGI1, MAP2K7, MAP3K9, MCF2L2, MCL1, MCTP2, MPP3, NOTCH4, NPY2R, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, P2RY5, PDE3A, PDE4C, PDE8B, PECAM1, PER2, PGF, PPARGC1A, PRKCB, RAB26, RAPGEF4, RET, RGS10, RLN1, ROS1, RRH, SFN, SH3BP2, SH3GL3, SIRPB1, SPN, SPRY1, TAAR2, TAC1, TACR1, TAS2R16, TAS2R9, TLR1, TP63, TPTE, TRPV1, TSHB, USP6, WNT6	1768	signal transduction
GO:0042742	2.138e-02	0.9783	6 FCER1G, HAMP, HTN1, IFNG, PGLYRP4, SPN	20	defense response to bacterium
GO:0006811	2.348e-02	13.99	28 ATP2C2, ATP5O, CATSPER2, CHRNA6, CSN2, CYBB, GABRR1, GLRA1, GLRA3, KCNJ14, KCNJ16, KCNMB4, P2RY4, PRKCB, RYR3, SCN10A, SCN11A, SLC10A1, SLC10A2, SLC11A1, SLC12A3, SLC17A6, SLC26A4, SLC4A5, SLCO1A2, SLCO1C1, TRPM3, TRPV1	286	ion transport
GO:0007154	2.385e-02	93.33	122 ACOT11, ADCY2, ADORA1, ADORA2A, ADRA1D, APBB2, ARAP2, BAIAP3, BCL2L11, BCL9, BMP10, BRS3, CCR9, CD28, CD53, CDKN1C, CEACAM1, CEACAM6, CHN2, CHRNA6, CHST4, CLEC4M, CNKSR2, CSF2RB, CXCL10, DAPP1, DNASE1L3, DRD5, DTX4, EDAR, EEF1D, EPAG, ERBB3, ERBB4, FCER1A, FCER1G, FGD2, FGD6, FGFR2, FGL1, FOXC1, FZD3, G3BP1, GAB1, GABRR1, GLRA1, GNAO1, GNG4, GNRHR, GP6, GPR12, GPR32, GRM6, HLA-DRB4, HTR1E, HTR1F, IFNG, IL12B, IL1RAPL1, IL2RB, INSR, ITK, KALRN, KCNMB4, LAT2, LAX1, LILRB4, LPAR4, LRRN2, MAGI1, MAP2K7, MAP3K9, MCF2L2, MCL1, MCTP2, MPP3, NOTCH4, NPY2R, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, P2RY5, PDE3A, PDE4C, PDE8B, PECAM1, PER2, PGF, PPARGC1A, PRKCB, RAB26, RAPGEF4, RET, RGS10, RLN1, ROS1, RRH, SFN, SH3BP2, SH3GL3, SIRPB1, SLC17A6, SLC1A2, SPN, SPRY1, SYN2, TAAR2, TAC1, TACR1, TAS2R16, TAS2R9, TLR1, TP63, TPTE, TRPV1, TSHB, USP6, VGF, WNT6	1908	cell communication
GO:0006955	2.446e-02	14.04	28 AKIRIN2, CCR9, CD28, CHST4, CLEC4E, CLEC4M, CR1, CXCL10, CYBB, CYP11B1, FCER1A, FCER1G, HAMP, HLA-DRB4, IFNG, IL12B, IL16, IL1RAPL1, LAT2, LAX1, LILRA5, LILRB4, MASP2, PGLYRP4, PLUNC, SPN, TBX21, TLR1	287	immune response
GO:0002438	2.968e-02	0.1957	3 FCER1A, FCER1G, SPN	4	acute inflammatory response to antigenic stimulus
GO:0002448	2.968e-02	0.1957	3 FCER1A, FCER1G, LAT2	4	mast cell mediated immunity
GO:0002524	2.968e-02	0.1957	3 FCER1A, FCER1G, SPN	4	hypersensitivity
GO:0002864	2.968e-02	0.1957	3 FCER1A, FCER1G, SPN	4	regulation of acute inflammatory response to antigenic stimulus
GO:0002883	2.968e-02	0.1957	3 FCER1A, FCER1G, SPN	4	regulation of hypersensitivity
GO:0043303	2.968e-02	0.1957	3 FCER1A, FCER1G, LAT2	4	mast cell degranulation
GO:0042035	3.130e-02	1.467	7 CD28, FCER1A, IFNG, IL12B, SPN, TLR1, ZNF287	30	regulation of cytokine biosynthetic process
GO:0007606	3.827e-02	1.125	6 OR2B2, OR2C1, OR2W1, OR7E24, TAS2R16, TAS2R9	23	sensory perception of chemical stimulus
GO:0007267	3.866e-02	12.47	25 ADORA1, ADORA2A, ADRA1D, BAIAP3, CEACAM6, CHRNA6, CHST4, CXCL10, DRD5, FCER1A, GABRR1, GLRA1, HTR1E, HTR1F, IFNG, KCNMB4, NTRK2, PGF, SLC17A6, SLC1A2, SPRY1, SYN2, TAC1, TSHB, VGF	255	cell-cell signaling
GO:0009410	4.224e-02	0.7827	5 CYP1A2, HAMP, HTN1, PON1, UGT2B28	16	response to xenobiotic stimulus
GO:0002706	4.487e-02	1.174	6 FCER1A, FCER1G, IFNG, IL12B, SPN, TBX21	24	regulation of lymphocyte mediated immunity

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005887	4.227e-07	27.46	60 ABCG1, ADORA1, ADORA2A, ADRA1D, CCR9, CD28, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CLEC4M, CR1, CSF2RB, CSPG5, CYBB, DRD5, ERBB3, ERBB4, FCER1A, FCER1G, FOLH1, FZD3, GABRR1, GLRA1, GNRHR, GP6, GPR12, GPR32, GRM6, HLA-DRB4, HTR1E, HTR1F, IL2RB, INSR, KCNJ14, KCNMB4, LPAR4, MEP1B, MPP3, NOTCH4, NPY2R, NTRK2, P2RY4, ROS1, RRH, SCN10A, SCN11A, SIRPB1, SLC10A1, SLC10A2, SLC11A1, SLC12A3, SLC15A1, SLC6A14, SPN, TACR1, TLR1, TNFRSF9, TRPV1, TSPAN15	535	integral to plasma membrane
GO:0031226	5.515e-07	27.66	60 ABCG1, ADORA1, ADORA2A, ADRA1D, CCR9, CD28, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CLEC4M, CR1, CSF2RB, CSPG5, CYBB, DRD5, ERBB3, ERBB4, FCER1A, FCER1G, FOLH1, FZD3, GABRR1, GLRA1, GNRHR, GP6, GPR12, GPR32, GRM6, HLA-DRB4, HTR1E, HTR1F, IL2RB, INSR, KCNJ14, KCNMB4, LPAR4, MEP1B, MPP3, NOTCH4, NPY2R, NTRK2, P2RY4, ROS1, RRH, SCN10A, SCN11A, SIRPB1, SLC10A1, SLC10A2, SLC11A1, SLC12A3, SLC15A1, SLC6A14, SPN, TACR1, TLR1, TNFRSF9, TRPV1, TSPAN15	539	intrinsic to plasma membrane
GO:0031224	1.211e-06	103.1	153 ABCG1, ABCG4, ACSL5, ACSL6, ADAM21, ADORA1, ADORA2A, ADRA1D, AKAP6, ATP2C2, ATRNL1, B4GALNT1, BEAN, BRS3, BTNL3, CA4, CADM4, CATSPER2, CCR9, CD28, CD53, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CHST4, CLDN10, CLDN18, CLEC4E, CLEC4M, CR1, CSF2RB, CSPG5, CTAGE1, CYBB, CYP3A4, DKFZP564O0823, DRD5, DSC2, EDAR, ERBB3, ERBB4, FA2H, FAM134B, FAM38B, FAM75A3, FCER1A, FCER1G, FCGR2A, FGFR2, FMO4, FOLH1, FUT2, FUT3, FZD3, GABRR1, GLRA1, GNRHR, GP6, GPR12, GPR32, GRM6, HAVCR1, HLA-DRB4, HS3ST2, HTR1E, HTR1F, IL1RAPL1, IL2RB, INSR, ITM2A, KCNJ14, KCNJ16, KCNMB4, KIAA1324, KMO, LAT2, LAX1, LILRA5, LILRB4, LOC23117, LOC93432, LPAR4, LRP4, LRRN2, LRRTM4, LY6H, MCL1, MCTP2, MEP1B, MFNG, MFSD11, MGAT4C, MGC5590, MOG, MPP3, NOTCH4, NPY2R, NRN1, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, PECAM1, PNPLA2, PRSS7, RET, ROS1, RP11-35N6.1, RRH, RYR3, SCARF1, SCD5, SCN10A, SCN11A, SEMA6D, SIRPB1, SLC10A1, SLC10A2, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC1A2, SLC26A10, SLC26A4, SLC4A5, SLC6A14, SLCO1A2, SLCO1C1, SPAM1, SPN, SPTLC3, ST3GAL2, ST8SIA3, TAAR2, TACR1, TAS2R16, TLR1, TMCC2, TMEM100, TMEM19, TNFRSF9, TPTE, TRPM3, TRPV1, TSPAN15, UGT1A8, UGT2B28, VAMP8, VEZT	2010	intrinsic to membrane
GO:0005886	4.368e-06	72.31	115 ABCG1, ACSL6, ADORA1, ADORA2A, ADRA1D, ATP5O, BCL2L11, BRS3, CA4, CAMK1G, CATSPER2, CCR9, CD28, CD53, CDH19, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CLDN10, CLDN18, CLEC4M, CNKSR2, CR1, CSF2RB, CSPG5, CYBB, DES, DRD5, DSC2, EDAR, ERBB3, ERBB4, FCER1A, FCER1G, FCGR2A, FGFR2, FOLH1, FZD3, G3BP1, GABRR1, GLRA1, GLRA3, GNG4, GNRHR, GP6, GPR12, GPR32, GRM6, HLA-DRB4, HTR1E, HTR1F, ICA1, IL2RB, INSR, ITK, ITM2A, KCNJ14, KCNMB4, LAT2, LAX1, LILRB4, LPAR4, LY6H, MAGI1, MEP1B, MOG, MPP3, MYO1A, NOTCH4, NPY2R, NRN1, NTNG1, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, P2RY5, PECAM1, PNPLA2, PRKCB, RAB26, RET, RIMS2, ROS1, RRH, SCN10A, SCN11A, SEMA6D, SIRPB1, SLC10A1, SLC10A2, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC4A5, SLC6A14, SLCO1A2, SPAM1, SPN, SPRY1, SYN2, TAAR2, TACR1, TAS2R16, TLR1, TNFRSF9, TP63, TRA@, TRPV1, TSPAN15, VEZT	1409	plasma membrane
GO:0016021	4.735e-06	101.8	149 ABCG1, ABCG4, ACSL5, ACSL6, ADAM21, ADORA1, ADORA2A, ADRA1D, AKAP6, ATP2C2, ATRNL1, B4GALNT1, BEAN, BRS3, BTNL3, CADM4, CATSPER2, CCR9, CD28, CD53, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CHST4, CLDN10, CLDN18, CLEC4E, CLEC4M, CR1, CSF2RB, CSPG5, CTAGE1, CYBB, CYP3A4, DKFZP564O0823, DRD5, DSC2, EDAR, ERBB3, ERBB4, FA2H, FAM134B, FAM38B, FAM75A3, FCER1A, FCER1G, FCGR2A, FGFR2, FMO4, FOLH1, FUT2, FUT3, FZD3, GABRR1, GLRA1, GNRHR, GP6, GPR12, GPR32, GRM6, HAVCR1, HLA-DRB4, HS3ST2, HTR1E, HTR1F, IL1RAPL1, IL2RB, INSR, ITM2A, KCNJ14, KCNJ16, KCNMB4, KIAA1324, KMO, LAT2, LAX1, LILRA5, LILRB4, LOC23117, LOC93432, LPAR4, LRP4, LRRN2, LRRTM4, MCL1, MCTP2, MEP1B, MFNG, MFSD11, MGAT4C, MGC5590, MOG, MPP3, NOTCH4, NPY2R, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, PECAM1, PNPLA2, PRSS7, RET, ROS1, RP11-35N6.1, RRH, RYR3, SCARF1, SCD5, SCN10A, SCN11A, SEMA6D, SIRPB1, SLC10A1, SLC10A2, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC1A2, SLC26A10, SLC26A4, SLC4A5, SLC6A14, SLCO1A2, SLCO1C1, SPN, SPTLC3, ST3GAL2, ST8SIA3, TAAR2, TACR1, TAS2R16, TLR1, TMCC2, TMEM100, TMEM19, TNFRSF9, TPTE, TRPM3, TRPV1, TSPAN15, UGT1A8, UGT2B28, VAMP8, VEZT	1983	integral to membrane
GO:0044425	1.909e-05	122.2	169 ABCG1, ABCG4, ACSL5, ACSL6, ADAM21, ADORA1, ADORA2A, ADRA1D, AKAP6, ATP2C2, ATP5O, ATRNL1, B4GALNT1, BEAN, BRS3, BTNL3, C8orf17, CA4, CADM4, CATSPER2, CCR9, CD28, CD53, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CHST4, CLDN10, CLDN18, CLEC4E, CLEC4M, CR1, CSF2RB, CSPG5, CTAGE1, CYBB, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2E1, CYP3A4, DKFZP564O0823, DRD5, DSC2, EDAR, EPB41L1, ERBB3, ERBB4, FA2H, FAM134B, FAM38B, FAM75A3, FCER1A, FCER1G, FCGR2A, FGFR2, FMO4, FOLH1, FUT2, FUT3, FZD3, GABRR1, GLRA1, GLRA3, GNG4, GNRHR, GP6, GPR12, GPR32, GRM6, HAVCR1, HLA-DRB4, HS3ST2, HTR1E, HTR1F, ICA1, IL1RAPL1, IL2RB, INSR, ITM2A, KCNJ14, KCNJ16, KCNMB4, KIAA1324, KMO, LAT2, LAX1, LILRA5, LILRB4, LOC23117, LOC93432, LPAR4, LRP4, LRRN2, LRRTM4, LY6H, MAGI1, MCL1, MCTP2, MEP1B, MFNG, MFSD11, MGAT4C, MGC5590, MOG, MPP3, MYO1A, NOTCH4, NPY2R, NRN1, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, PECAM1, PNPLA2, PRSS7, RET, RIMS2, ROS1, RP11-35N6.1, RRH, RYR3, SCARF1, SCD5, SCN10A, SCN11A, SEMA6D, SIRPB1, SLC10A1, SLC10A2, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC1A2, SLC26A10, SLC26A4, SLC4A5, SLC6A14, SLCO1A2, SLCO1C1, SPAM1, SPN, SPTLC3, ST3GAL2, ST8SIA3, SYN2, TAAR2, TACR1, TAS2R16, TLR1, TMCC2, TMEM100, TMEM19, TNFRSF9, TP63, TPTE, TRPM3, TRPV1, TSPAN15, UGT1A8, UGT2B28, VAMP8, VEZT	2382	membrane part
GO:0044459	9.439e-05	43.88	75 ABCG1, ADORA1, ADORA2A, ADRA1D, CCR9, CD28, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CLDN10, CLDN18, CLEC4M, CR1, CSF2RB, CSPG5, CYBB, DRD5, DSC2, ERBB3, ERBB4, FCER1A, FCER1G, FOLH1, FZD3, GABRR1, GLRA1, GLRA3, GNG4, GNRHR, GP6, GPR12, GPR32, GRM6, HLA-DRB4, HTR1E, HTR1F, ICA1, IL2RB, INSR, KCNJ14, KCNMB4, LPAR4, MAGI1, MEP1B, MPP3, MYO1A, NOTCH4, NPY2R, NTRK2, P2RY4, RIMS2, ROS1, RRH, SCN10A, SCN11A, SIRPB1, SLC10A1, SLC10A2, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC4A5, SLC6A14, SPN, SYN2, TACR1, TAS2R16, TLR1, TNFRSF9, TP63, TRPV1, TSPAN15, VEZT	855	plasma membrane part
GO:0016020	2.763e-04	159.9	203 ABCG1, ABCG4, ACSL5, ACSL6, ADAM21, ADCY2, ADORA1, ADORA2A, ADRA1D, AKAP6, APBB2, ATP2C2, ATP5O, ATP8A1, ATRNL1, B4GALNT1, BCL2L11, BEAN, BRS3, BTNL3, C8orf17, CA4, CADM4, CAMK1G, CATSPER2, CCR9, CD28, CD53, CDH19, CEACAM1, CEACAM5, CEACAM6, CHN2, CHRNA6, CHST4, CLDN10, CLDN18, CLEC4E, CLEC4M, CNKSR2, COX5B, CR1, CSF2RB, CSPG5, CTAGE1, CYBB, CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2E1, CYP3A4, DAPP1, DES, DKFZP564O0823, DRD5, DSC2, EDAR, EPB41L1, ERBB3, ERBB4, F11, FA2H, FAM134B, FAM38B, FAM75A3, FCER1A, FCER1G, FCGR2A, FGFR2, FMO4, FOLH1, FUT2, FUT3, FZD3, G3BP1, GABRR1, GK2, GLRA1, GLRA3, GNG4, GNRHR, GP6, GPR12, GPR32, GRM6, HAVCR1, HLA-DRB4, HS3ST2, HTR1E, HTR1F, ICA1, IL12B, IL1RAPL1, IL2RB, INSR, ITK, ITM2A, KCNJ14, KCNJ16, KCNMB4, KIAA1324, KMO, LAT2, LAX1, LILRA5, LILRB4, LOC23117, LOC93432, LPAR4, LRP4, LRRN2, LRRTM4, LY6H, MAGI1, MCL1, MCTP2, MEP1B, MFNG, MFSD11, MGAT4C, MGC5590, MOG, MPP3, MYO1A, N4BP3, NOTCH4, NPY2R, NRN1, NTNG1, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, P2RY5, PDE3A, PECAM1, PELI2, PGF, PGLYRP4, PIP5K1B, PNPLA2, PRKCB, PRSS7, RAB26, RAPGEF4, RET, RIMS2, ROS1, RP11-35N6.1, RRH, RYR3, SCARF1, SCD5, SCN10A, SCN11A, SEMA6D, SH3GL3, SIRPB1, SLC10A1, SLC10A2, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC1A2, SLC1A7, SLC26A10, SLC26A4, SLC4A5, SLC6A14, SLCO1A2, SLCO1C1, SPAM1, SPN, SPRY1, SPTLC3, ST3GAL2, ST8SIA3, SYN2, TAAR2, TACR1, TAS2R16, TAS2R9, TIMM8A, TLR1, TMCC2, TMEM100, TMEM19, TNFRSF9, TP63, TPTE, TRA@, TRPM3, TRPV1, TSPAN15, UGT1A8, UGT2B28, VAMP8, VEZT	3116	membrane
GO:0005576	3.300e-04	34.54	61 ADAMDEC1, ADAMTS9, ADAMTSL3, APOD, BMP10, C10orf59, CEACAM1, CHI3L1, CLEC4M, COL11A2, CSN2, CXCL10, ERBB3, F11, FGFR2, FGL1, GZMM, HAMP, HTN1, IFNA16, IFNA5, IFNG, IL12B, IL16, ITIH2, KERA, KNG1, LAMB4, LILRA5, MASP2, MEP1B, MFNG, MIA2, MMRN2, MSTP9, MUC5AC, NOTCH4, NTNG1, PECAM1, PGC, PGF, PLA2G7, PLGLB1, PLUNC, PON1, PRB3, PROL1, PSG7, RLN1, SERPINA7, SFN, SFTPB, SPARCL1, SPINLW1, SPN, ST3GAL2, TAC1, TSHB, VGF, WNT6, ZPBP	673	extracellular region
GO:0005626	9.476e-03	18.94	35 ACSL5, ADORA2A, B4GALNT1, BCL2L11, C8orf17, CA4, CEACAM1, CSPG5, CYP1A2, CYP2A6, CYP2C9, CYP2E1, CYP3A4, DES, FA2H, FOLH1, FUT3, GLRA1, INSR, MCTP2, MEP1B, PDE3A, PON1, RAPGEF4, ROS1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC1A2, TSPAN15, UGT1A8, UGT2B28, VAMP8	369	insoluble fraction
GO:0005624	1.879e-02	18.27	33 ACSL5, ADORA2A, B4GALNT1, BCL2L11, C8orf17, CA4, CEACAM1, CSPG5, CYP1A2, CYP2A6, CYP2C9, CYP2E1, CYP3A4, FA2H, FOLH1, FUT3, GLRA1, INSR, MCTP2, MEP1B, PON1, RAPGEF4, ROS1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC1A2, TSPAN15, UGT1A8, UGT2B28, VAMP8	356	membrane fraction
GO:0044421	2.328e-02	19.3	34 ADAMTS9, ADAMTSL3, APOD, BMP10, CHI3L1, COL11A2, CXCL10, ERBB3, F11, FGL1, IFNA16, IFNA5, IFNG, IL12B, IL16, KERA, LAMB4, MEP1B, MFNG, MMRN2, MUC5AC, NOTCH4, NTNG1, PECAM1, PGC, PON1, SERPINA7, SFN, SFTPB, SPARCL1, SPN, TAC1, VGF, WNT6	376	extracellular region part
GO:0005615	2.808e-02	12.16	24 APOD, BMP10, CHI3L1, CXCL10, ERBB3, F11, FGL1, IFNA16, IFNA5, IFNG, IL12B, IL16, MEP1B, MFNG, NOTCH4, PECAM1, PGC, PON1, SERPINA7, SFN, SFTPB, SPN, TAC1, VGF	237	extracellular space
GO:0005792	4.356e-02	4.567	12 ACSL5, C8orf17, CYP1A2, CYP2A6, CYP2C9, CYP2E1, CYP3A4, FA2H, INSR, PON1, UGT1A8, UGT2B28	89	microsome
GO:0042598	4.706e-02	4.619	12 ACSL5, C8orf17, CYP1A2, CYP2A6, CYP2C9, CYP2E1, CYP3A4, FA2H, INSR, PON1, UGT1A8, UGT2B28	90	vesicular fraction

Id	Pvalue	ExpCount	Count	Size	Term
GO:0004888	1.844e-10	15.76	52 ADORA1, ADORA2A, ADRA1D, BRS3, CCR9, CHRNA6, CLEC4M, CR1, CSF2RB, DRD5, EDAR, ERBB3, ERBB4, FCER1A, FCER1G, FGFR2, FZD3, GABRR1, GLRA1, GLRA3, GNRHR, GP6, GPR12, GPR32, GRM6, HLA-DRB4, HTR1E, HTR1F, IL12B, IL1RAPL1, IL2RB, INSR, LPAR4, NPY2R, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, P2RY5, PRSS7, RET, ROS1, RRH, SCARF1, SPN, TAAR2, TACR1, TAS2R16, TAS2R9, TLR1	324	transmembrane receptor activity
GO:0004872	4.222e-09	25.25	65 ADORA1, ADORA2A, ADRA1D, BRS3, CCR9, CD28, CHRNA6, CLEC4M, CR1, CSF2RB, DRD5, EDAR, ERBB3, ERBB4, FCER1A, FCER1G, FCGR2A, FGFR2, FZD3, GABRR1, GLRA1, GLRA3, GNRHR, GP6, GPR12, GPR32, GRM6, HAVCR1, HLA-DRB4, HTR1E, HTR1F, IL12B, IL1RAPL1, IL2RB, INSR, LILRA5, LILRB4, LPAR4, LRP4, LRRN2, NOTCH4, NPY2R, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, P2RY5, PGLYRP4, PRSS7, RET, ROS1, RRH, RYR3, SCARF1, SEMA6D, SPN, TAAR2, TACR1, TAS2R16, TAS2R9, TLR1, TNFRSF9, TRA@	519	receptor activity
GO:0004930	9.569e-07	6.373	26 ADORA1, ADORA2A, ADRA1D, BRS3, CCR9, DRD5, FZD3, GNRHR, GPR12, GPR32, GRM6, HTR1E, HTR1F, LPAR4, NPY2R, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, P2RY5, RRH, TAAR2, TACR1, TAS2R16, TAS2R9	131	G-protein coupled receptor activity
GO:0004871	1.842e-06	37.95	76 ADORA1, ADORA2A, ADRA1D, BRS3, CCR9, CD28, CHN2, CHRNA6, CLEC4M, CR1, CSF2RB, DRD5, EDAR, EEF1D, EPAG, ERBB3, ERBB4, FCER1A, FCER1G, FCGR2A, FGFR2, FZD3, GAB1, GABRR1, GLRA1, GLRA3, GNAO1, GNG4, GNRHR, GP6, GPR12, GPR32, GRM6, HAVCR1, HLA-DRB4, HTR1E, HTR1F, IL12B, IL1RAPL1, IL2RB, INSR, LILRA5, LILRB4, LPAR4, LRP4, LRRN2, NOTCH4, NPY2R, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, P2RY5, PDE8B, PER2, PGLYRP4, PRSS7, RET, RGS10, ROS1, RRH, RYR3, SCARF1, SEMA6D, SH3BP2, SPN, TAAR2, TACR1, TAS2R16, TAS2R9, TLR1, TNFRSF9, TRA@, WNT6	780	signal transducer activity
GO:0060089	1.842e-06	37.95	76 ADORA1, ADORA2A, ADRA1D, BRS3, CCR9, CD28, CHN2, CHRNA6, CLEC4M, CR1, CSF2RB, DRD5, EDAR, EEF1D, EPAG, ERBB3, ERBB4, FCER1A, FCER1G, FCGR2A, FGFR2, FZD3, GAB1, GABRR1, GLRA1, GLRA3, GNAO1, GNG4, GNRHR, GP6, GPR12, GPR32, GRM6, HAVCR1, HLA-DRB4, HTR1E, HTR1F, IL12B, IL1RAPL1, IL2RB, INSR, LILRA5, LILRB4, LPAR4, LRP4, LRRN2, NOTCH4, NPY2R, NTRK2, OR2B2, OR2C1, OR2W1, OR7E24, P2RY4, P2RY5, PDE8B, PER2, PGLYRP4, PRSS7, RET, RGS10, ROS1, RRH, RYR3, SCARF1, SEMA6D, SH3BP2, SPN, TAAR2, TACR1, TAS2R16, TAS2R9, TLR1, TNFRSF9, TRA@, WNT6	780	molecular transducer activity
GO:0004497	1.447e-04	1.654	11 C10orf59, CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2E1, CYP3A4, DOHH, FMO4, KMO	34	monooxygenase activity
GO:0019825	3.303e-04	0.4378	6 CYP1A2, CYP2A6, CYP2E1, CYP3A4, HBB, MB	9	oxygen binding
GO:0016712	4.866e-04	0.2919	5 CYP1A2, CYP2A6, CYP2B6, CYP2E1, CYP3A4	6	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0001608	1.269e-03	0.3405	5 ADORA1, ADORA2A, LPAR4, P2RY4, P2RY5	7	nucleotide receptor activity, G-protein coupled
GO:0045028	1.269e-03	0.3405	5 ADORA1, ADORA2A, LPAR4, P2RY4, P2RY5	7	purinergic nucleotide receptor activity, G-protein coupled
GO:0020037	1.343e-03	2.141	11 CYBB, CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2E1, CYP3A4, FA2H, HBB, MB	44	heme binding
GO:0046906	1.343e-03	2.141	11 CYBB, CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2E1, CYP3A4, FA2H, HBB, MB	44	tetrapyrrole binding
GO:0030594	1.690e-03	1.119	8 BRS3, CHRNA6, DRD5, GABRR1, GLRA1, GLRA3, NPY2R, TACR1	23	neurotransmitter receptor activity
GO:0042165	1.690e-03	1.119	8 BRS3, CHRNA6, DRD5, GABRR1, GLRA1, GLRA3, NPY2R, TACR1	23	neurotransmitter binding
GO:0016705	3.235e-03	2.822	12 CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2E1, CYP3A4, DOHH, EGLN3, FMO4, KMO, SCD5	58	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0001614	4.812e-03	0.4378	5 ADORA1, ADORA2A, LPAR4, P2RY4, P2RY5	9	purinergic nucleotide receptor activity
GO:0016502	4.812e-03	0.4378	5 ADORA1, ADORA2A, LPAR4, P2RY4, P2RY5	9	nucleotide receptor activity
GO:0015125	1.426e-02	0.1459	3 SLC10A1, SLC10A2, SLCO1A2	3	bile acid transmembrane transporter activity
GO:0015075	3.125e-02	14.01	28 ATP2C2, ATP5O, ATP8A1, CATSPER2, CHRNA6, COX5B, CYBB, GABRR1, GLRA1, GLRA3, KCNJ14, KCNJ16, KCNMB4, RYR3, SCN10A, SCN11A, SLC10A1, SLC10A2, SLC12A3, SLC15A1, SLC1A2, SLC1A7, SLC26A4, SLC4A5, SLC6A14, SLCO1A2, TRPM3, TRPV1	288	ion transmembrane transporter activity
GO:0015267	3.218e-02	5.497	15 CATSPER2, CHRNA6, CYBB, GABRR1, GLRA1, GLRA3, KCNJ14, KCNJ16, KCNMB4, MCL1, RYR3, SCN10A, SCN11A, TRPM3, TRPV1	113	channel activity
GO:0022803	3.218e-02	5.497	15 CATSPER2, CHRNA6, CYBB, GABRR1, GLRA1, GLRA3, KCNJ14, KCNJ16, KCNMB4, MCL1, RYR3, SCN10A, SCN11A, TRPM3, TRPV1	113	passive transmembrane transporter activity
GO:0008188	3.751e-02	0.1946	3 BRS3, NPY2R, TACR1	4	neuropeptide receptor activity
GO:0042923	3.751e-02	0.1946	3 BRS3, NPY2R, TACR1	4	neuropeptide binding
GO:0004984	4.442e-02	0.4378	4 OR2B2, OR2C1, OR2W1, OR7E24	9	olfactory receptor activity

Id	Pvalue	ExpCount	Count	Size	Term
04080	5.784e-07	4.208	20 ADORA1, ADORA2A, ADRA1D, BRS3, DRD5, GABRR1, GLRA1, GLRA3, GNRHR, GRM6, HTR1E, HTR1F, LPAR4, NPY2R, P2RY4, P2RY5, TAAR2, TACR1, TRPV1, TSHB	78	Neuroactive ligand-receptor interaction
00830	6.971e-03	1.133	7 CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP3A4, UGT1A8, UGT2B28	21	Retinol metabolism
00982	7.794e-03	1.942	9 CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2E1, CYP3A4, FMO4, UGT1A8, UGT2B28	36	Drug metabolism - cytochrome P450
00591	4.506e-02	0.4855	4 CYP1A2, CYP2C9, CYP2E1, CYP3A4	9	Linoleic acid metabolism

No enriched terms

No enriched terms

Entrez genes

A1CFAPOBEC1 complementation factor (220951_s_at), score: 0.64 ABCG1ATP-binding cassette, sub-family G (WHITE), member 1 (204567_s_at), score: 0.59 ABCG4ATP-binding cassette, sub-family G (WHITE), member 4 (207593_at), score: 0.5 ABI3BPABI family, member 3 (NESH) binding protein (220518_at), score: 0.57 ACOT11acyl-CoA thioesterase 11 (216103_at), score: 0.9 ACRV1acrosomal vesicle protein 1 (207969_x_at), score: 0.52 ACSL5acyl-CoA synthetase long-chain family member 5 (218322_s_at), score: 0.53 ACSL6acyl-CoA synthetase long-chain family member 6 (211207_s_at), score: 0.51 ADAM21ADAM metallopeptidase domain 21 (207665_at), score: 0.5 ADAMDEC1ADAM-like, decysin 1 (206134_at), score: 0.73 ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif, 9 (220287_at), score: 0.6 ADAMTSL3ADAMTS-like 3 (213974_at), score: 0.68 ADCY2adenylate cyclase 2 (brain) (217687_at), score: 0.63 ADORA1adenosine A1 receptor (216220_s_at), score: 0.69 ADORA2Aadenosine A2a receptor (205013_s_at), score: 0.59 ADRA1Dadrenergic, alpha-1D-, receptor (210961_s_at), score: 0.48 AGBL2ATP/GTP binding protein-like 2 (220390_at), score: 0.48 AGMATagmatine ureohydrolase (agmatinase) (219792_at), score: 0.6 AIPL1aryl hydrocarbon receptor interacting protein-like 1 (219977_at), score: 0.68 AKAP6A kinase (PRKA) anchor protein 6 (205359_at), score: 0.68 AKIRIN2akirin 2 (213810_s_at), score: 0.61 AKR1D1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (207102_at), score: 0.63 ALDOAP2aldolase A, fructose-bisphosphate pseudogene 2 (211617_at), score: 0.79 ALMS1Alstrom syndrome 1 (214707_x_at), score: 0.79 ANKRD36Bankyrin repeat domain 36B (220940_at), score: 0.52 APBB2amyloid beta (A4) precursor protein-binding, family B, member 2 (212972_x_at), score: 0.57 APODapolipoprotein D (201525_at), score: 0.64 ARAP2ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 (214102_at), score: 0.61 ARID4AAT rich interactive domain 4A (RBP1-like) (205062_x_at), score: 0.51 ARL17P1ADP-ribosylation factor-like 17 pseudogene 1 (210718_s_at), score: 0.51 ATF7IP2activating transcription factor 7 interacting protein 2 (219870_at), score: 0.5 ATP2C2ATPase, Ca++ transporting, type 2C, member 2 (214798_at), score: 0.49 ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (216954_x_at), score: 0.83 ATP8A1ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (213106_at), score: 0.59 ATRNL1attractin-like 1 (213744_at), score: 0.57 B4GALNT1beta-1,4-N-acetyl-galactosaminyl transferase 1 (206435_at), score: 0.53 BACH2BTB and CNC homology 1, basic leucine zipper transcription factor 2 (221234_s_at), score: 0.77 BAIAP3BAI1-associated protein 3 (216356_x_at), score: 0.58 BCL2L11BCL2-like 11 (apoptosis facilitator) (222343_at), score: 0.59 BCL9B-cell CLL/lymphoma 9 (204129_at), score: 0.73 BEANbrain expressed, associated with Nedd4 (214068_at), score: 0.7 BHLHB9basic helix-loop-helix domain containing, class B, 9 (213709_at), score: 0.5 BMP10bone morphogenetic protein 10 (208292_at), score: 0.61 BRS3bombesin-like receptor 3 (207369_at), score: 0.63 BTNL3butyrophilin-like 3 (217207_s_at), score: 0.57 C10orf110chromosome 10 open reading frame 110 (220703_at), score: 0.74 C10orf59chromosome 10 open reading frame 59 (220564_at), score: 0.57 C11orf1chromosome 11 open reading frame 1 (218925_s_at), score: 0.65 C15orf5chromosome 15 open reading frame 5 (208109_s_at), score: 0.74 C17orf86chromosome 17 open reading frame 86 (221621_at), score: 0.62 C1orf61chromosome 1 open reading frame 61 (205103_at), score: 0.57 C1orf69chromosome 1 open reading frame 69 (215490_at), score: 0.59 C20orf12chromosome 20 open reading frame 12 (219951_s_at), score: 0.5 C21orf2chromosome 21 open reading frame 2 (203996_s_at), score: 0.61 C7orf28Achromosome 7 open reading frame 28A (201974_s_at), score: 0.86 C8orf17chromosome 8 open reading frame 17 (208266_at), score: 0.49 C8orf60chromosome 8 open reading frame 60 (220712_at), score: 0.6 C9orf33chromosome 9 open reading frame 33 (217130_at), score: 0.56 CA1carbonic anhydrase I (205949_at), score: 0.54 CA4carbonic anhydrase IV (206209_s_at), score: 0.72 CADM4cell adhesion molecule 4 (222293_at), score: 0.65 CAMK1Gcalcium/calmodulin-dependent protein kinase IG (217128_s_at), score: 0.5 CAPN9calpain 9 (210641_at), score: 0.5 CASQ1calsequestrin 1 (fast-twitch, skeletal muscle) (219645_at), score: 0.66 CASZ1castor zinc finger 1 (220015_at), score: 0.51 CATSPER2cation channel, sperm associated 2 (217588_at), score: 0.84 CBFA2T2core-binding factor, runt domain, alpha subunit 2; translocated to, 2 (207625_s_at), score: 0.53 CCR9chemokine (C-C motif) receptor 9 (207445_s_at), score: 0.76 CD28CD28 molecule (206545_at), score: 0.54 CD53CD53 molecule (203416_at), score: 0.75 CDC14ACDC14 cell division cycle 14 homolog A (S. cerevisiae) (205288_at), score: 0.54 CDH19cadherin 19, type 2 (206898_at), score: 0.53 CDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2) (213183_s_at), score: 0.64 CDR1cerebellar degeneration-related protein 1, 34kDa (207276_at), score: 0.74 CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (211883_x_at), score: 0.51 CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5 (201884_at), score: 0.92 CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (211657_at), score: 0.52 CEP152centrosomal protein 152kDa (215170_s_at), score: 0.55 CEP27centrosomal protein 27kDa (220071_x_at), score: 0.81 CGGBP1CGG triplet repeat binding protein 1 (214050_at), score: 0.95 CHD2chromodomain helicase DNA binding protein 2 (203461_at), score: 0.75 CHI3L1chitinase 3-like 1 (cartilage glycoprotein-39) (209395_at), score: 0.61 CHN2chimerin (chimaerin) 2 (207486_x_at), score: 0.76 CHRNA6cholinergic receptor, nicotinic, alpha 6 (207568_at), score: 0.68 CHST4carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (220446_s_at), score: 0.56 CIRBPcold inducible RNA binding protein (200811_at), score: 0.57 CLDN10claudin 10 (205328_at), score: 0.73 CLDN18claudin 18 (214135_at), score: 0.52 CLEC4EC-type lectin domain family 4, member E (219859_at), score: 0.77 CLEC4MC-type lectin domain family 4, member M (207995_s_at), score: 0.49 CNKSR2connector enhancer of kinase suppressor of Ras 2 (206731_at), score: 0.69 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: 0.54 COX5Bcytochrome c oxidase subunit Vb (213736_at), score: 0.49 CR1complement component (3b/4b) receptor 1 (Knops blood group) (217484_at), score: 0.57 CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (205159_at), score: 0.63 CSN2casein beta (207951_at), score: 0.5 CSPG5chondroitin sulfate proteoglycan 5 (neuroglycan C) (39966_at), score: 0.6 CTAGE1cutaneous T-cell lymphoma-associated antigen 1 (220957_at), score: 0.65 CTSEcathepsin E (205927_s_at), score: 0.57 CTTNBP2NLCTTNBP2 N-terminal like (214731_at), score: 0.72 CXCL10chemokine (C-X-C motif) ligand 10 (204533_at), score: 0.52 CXorf21chromosome X open reading frame 21 (220252_x_at), score: 0.7 CYBBcytochrome b-245, beta polypeptide (217431_x_at), score: 0.65 CYLC1cylicin, basic protein of sperm head cytoskeleton 1 (216809_at), score: 0.76 CYP11B1cytochrome P450, family 11, subfamily B, polypeptide 1 (214610_at), score: 0.66 CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 2 (207608_x_at), score: 0.51 CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6 (211295_x_at), score: 0.51 CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 6 (217133_x_at), score: 0.74 CYP2B7P1cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1 (210272_at), score: 0.54 CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 9 (214421_x_at), score: 0.9 CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1 (1431_at), score: 0.55 CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 4 (205998_x_at), score: 0.67 DAOD-amino-acid oxidase (206878_at), score: 0.49 DAPP1dual adaptor of phosphotyrosine and 3-phosphoinositides (219290_x_at), score: 0.82 DAZ1deleted in azoospermia 1 (216922_x_at), score: 0.88 DAZ3deleted in azoospermia 3 (208281_x_at), score: 0.74 DAZ4deleted in azoospermia 4 (216351_x_at), score: 0.86 DBC1deleted in bladder cancer 1 (205818_at), score: 0.5 DDX6DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (204909_at), score: 0.55 DEM1defects in morphology 1 homolog (S. cerevisiae) (219567_s_at), score: 0.5 DESdesmin (216947_at), score: 0.8 DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila) (215529_x_at), score: 0.63 DKFZP564O0823DKFZP564O0823 protein (204687_at), score: 0.53 DKFZp686O1327hypothetical gene supported by BC043549; BX648102 (216877_at), score: 0.9 DLX4distal-less homeobox 4 (208216_at), score: 0.84 DNAH7dynein, axonemal, heavy chain 7 (214222_at), score: 0.72 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: 0.65 DNM3dynamin 3 (209839_at), score: 0.64 DOHHdeoxyhypusine hydroxylase/monooxygenase (208141_s_at), score: 0.68 DPY19L2P2dpy-19-like 2 pseudogene 2 (C. elegans) (215143_at), score: 0.55 DRD5dopamine receptor D5 (208486_at), score: 0.62 DSC2desmocollin 2 (204751_x_at), score: 0.57 DTX4deltex homolog 4 (Drosophila) (212611_at), score: 0.58 DXS542X-linked retinopathy protein-like (222247_at), score: 0.6 EDARectodysplasin A receptor (220048_at), score: 0.53 EEF1Deukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) (214395_x_at), score: 0.58 EFHC2EF-hand domain (C-terminal) containing 2 (220591_s_at), score: 0.51 EGLN3egl nine homolog 3 (C. elegans) (219232_s_at), score: 0.58 ELK4ELK4, ETS-domain protein (SRF accessory protein 1) (206919_at), score: 0.79 ELL3elongation factor RNA polymerase II-like 3 (219517_at), score: 0.78 EPAGearly lymphoid activation protein (217050_at), score: 0.86 EPB41L1erythrocyte membrane protein band 4.1-like 1 (212339_at), score: 0.67 ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (202454_s_at), score: 0.56 ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (214053_at), score: 0.73 F11coagulation factor XI (206610_s_at), score: 0.5 FA2Hfatty acid 2-hydroxylase (219429_at), score: 0.55 FABP7fatty acid binding protein 7, brain (205030_at), score: 0.61 FAM106Afamily with sequence similarity 106, member A (220575_at), score: 0.66 FAM134Bfamily with sequence similarity 134, member B (218532_s_at), score: 0.58 FAM38Bfamily with sequence similarity 38, member B (219602_s_at), score: 0.53 FAM46Cfamily with sequence similarity 46, member C (220306_at), score: 0.74 FAM75A3family with sequence similarity 75, member A3 (215935_at), score: 0.87 FBXO41F-box protein 41 (44040_at), score: 0.88 FBXW12F-box and WD repeat domain containing 12 (215600_x_at), score: 0.55 FCER1AFc fragment of IgE, high affinity I, receptor for; alpha polypeptide (211734_s_at), score: 0.65 FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide (204232_at), score: 0.51 FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32) (203561_at), score: 0.54 FETUBfetuin B (214417_s_at), score: 0.5 FGD2FYVE, RhoGEF and PH domain containing 2 (215602_at), score: 0.57 FGD6FYVE, RhoGEF and PH domain containing 6 (219901_at), score: 0.69 FGFR2fibroblast growth factor receptor 2 (208229_at), score: 0.62 FGL1fibrinogen-like 1 (205305_at), score: 0.68 FKSG2apoptosis inhibitor (208588_at), score: 0.61 FLJ10038hypothetical protein FLJ10038 (205510_s_at), score: 0.52 FLJ11292hypothetical protein FLJ11292 (220828_s_at), score: 0.69 FLJ21369hypothetical protein FLJ21369 (220401_at), score: 0.76 FLJ23172hypothetical LOC389177 (217016_x_at), score: 0.78 FMO4flavin containing monooxygenase 4 (206263_at), score: 0.55 FOLH1folate hydrolase (prostate-specific membrane antigen) 1 (217487_x_at), score: 0.82 FOXC1forkhead box C1 (213260_at), score: 0.5 FUT2fucosyltransferase 2 (secretor status included) (210608_s_at), score: 0.66 FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (214088_s_at), score: 0.83 FZD3frizzled homolog 3 (Drosophila) (219683_at), score: 0.5 G3BP1GTPase activating protein (SH3 domain) binding protein 1 (222187_x_at), score: 0.85 GAB1GRB2-associated binding protein 1 (207112_s_at), score: 0.53 GABRR1gamma-aminobutyric acid (GABA) receptor, rho 1 (206525_at), score: 0.52 GATA3GATA binding protein 3 (209604_s_at), score: 0.53 GK2glycerol kinase 2 (215430_at), score: 0.87 GLRA1glycine receptor, alpha 1 (207972_at), score: 0.61 GLRA3glycine receptor, alpha 3 (210661_at), score: 0.56 GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (204762_s_at), score: 0.51 GNG4guanine nucleotide binding protein (G protein), gamma 4 (205184_at), score: 0.8 GNRHRgonadotropin-releasing hormone receptor (216341_s_at), score: 0.7 GP6glycoprotein VI (platelet) (220336_s_at), score: 0.69 GPATCH4G patch domain containing 4 (220596_at), score: 0.56 GPR12G protein-coupled receptor 12 (214558_at), score: 0.58 GPR32G protein-coupled receptor 32 (221469_at), score: 0.49 GRHL2grainyhead-like 2 (Drosophila) (219388_at), score: 0.81 GRM6glutamate receptor, metabotropic 6 (208035_at), score: 0.82 GZMMgranzyme M (lymphocyte met-ase 1) (207460_at), score: 0.75 HAMPhepcidin antimicrobial peptide (220491_at), score: 0.48 HAND1heart and neural crest derivatives expressed 1 (220138_at), score: 0.69 HAO2hydroxyacid oxidase 2 (long chain) (220801_s_at), score: 0.89 HAVCR1hepatitis A virus cellular receptor 1 (207052_at), score: 0.57 HBBhemoglobin, beta (211696_x_at), score: 0.76 HCG2P7HLA complex group 2 pseudogene 7 (216229_x_at), score: 0.6 HIST1H4Dhistone cluster 1, H4d (208076_at), score: 0.67 HIVEP2human immunodeficiency virus type I enhancer binding protein 2 (212642_s_at), score: 0.59 HLA-DRB4major histocompatibility complex, class II, DR beta 4 (208306_x_at), score: 0.52 HNRNPDheterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) (213359_at), score: 0.7 HOXD4homeobox D4 (205522_at), score: 0.62 HS3ST2heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (219697_at), score: 0.5 HTN1histatin 1 (206639_x_at), score: 0.56 HTR1E5-hydroxytryptamine (serotonin) receptor 1E (207404_s_at), score: 0.64 HTR1F5-hydroxytryptamine (serotonin) receptor 1F (221458_at), score: 0.58 IBD12Inflammatory bowel disease 12 (215373_x_at), score: 0.77 ICA1islet cell autoantigen 1, 69kDa (211740_at), score: 0.59 IFNA16interferon, alpha 16 (208448_x_at), score: 0.86 IFNA5interferon, alpha 5 (214569_at), score: 0.63 IFNGinterferon, gamma (210354_at), score: 0.67 IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (207901_at), score: 0.52 IL16interleukin 16 (lymphocyte chemoattractant factor) (209827_s_at), score: 0.56 IL1RAPL1interleukin 1 receptor accessory protein-like 1 (220663_at), score: 0.53 IL2RBinterleukin 2 receptor, beta (205291_at), score: 0.5 INE1inactivation escape 1 (non-protein coding) (207252_at), score: 0.62 INSRinsulin receptor (213792_s_at), score: 0.52 ISL1ISL LIM homeobox 1 (206104_at), score: 0.49 ITIH2inter-alpha (globulin) inhibitor H2 (204987_at), score: 0.5 ITKIL2-inducible T-cell kinase (211339_s_at), score: 0.55 ITM2Aintegral membrane protein 2A (202746_at), score: 0.61 KALRNkalirin, RhoGEF kinase (206078_at), score: 0.48 KCNJ14potassium inwardly-rectifying channel, subfamily J, member 14 (220776_at), score: 0.65 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: 0.9 KCNMB4potassium large conductance calcium-activated channel, subfamily M, beta member 4 (219287_at), score: 0.63 KERAkeratocan (220504_at), score: 0.57 KIAA1324KIAA1324 (221874_at), score: 0.64 KIR3DX1killer cell immunoglobulin-like receptor, three domains, X1 (216428_x_at), score: 0.66 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: 0.73 KLF11Kruppel-like factor 11 (218486_at), score: 0.51 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (205307_s_at), score: 0.64 KNG1kininogen 1 (217512_at), score: 0.5 KRT2keratin 2 (207908_at), score: 0.7 KRT8P12keratin 8 pseudogene 12 (222060_at), score: 0.49 LAMB4laminin, beta 4 (215516_at), score: 0.74 LAT2linker for activation of T cells family, member 2 (211768_at), score: 0.5 LAX1lymphocyte transmembrane adaptor 1 (207734_at), score: 0.66 LGALS14lectin, galactoside-binding, soluble, 14 (220158_at), score: 0.66 LHX3LIM homeobox 3 (221670_s_at), score: 0.78 LILRA5leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 (215838_at), score: 0.55 LILRB4leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 (210152_at), score: 0.59 LLPHLLP homolog, long-term synaptic facilitation (Aplysia) (209779_at), score: 0.54 LOC100128701heterogeneous nuclear ribonucleoprotein A1-like 2 pseudogene (216497_at), score: 0.57 LOC100128836similar to heterogeneous nuclear ribonucleoprotein A1 (217353_at), score: 0.59 LOC100129624hypothetical LOC100129624 (210748_at), score: 0.73 LOC100130233similar to NPM1 protein (216387_x_at), score: 0.81 LOC100130703similar to hCG2042168 (207596_at), score: 0.53 LOC100132247similar to Uncharacterized protein KIAA0220 (215002_at), score: 0.69 LOC100134401hypothetical protein LOC100134401 (213605_s_at), score: 0.69 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: 0.67 LOC202181hypothetical protein LOC202181 (220609_at), score: 0.59 LOC23117PI-3-kinase-related kinase SMG-1 isoform 1 homolog (211996_s_at), score: 0.77 LOC440345hypothetical protein LOC440345 (214984_at), score: 0.57 LOC51152melanoma antigen (220771_at), score: 0.67 LOC647070hypothetical LOC647070 (215467_x_at), score: 0.52 LOC728844hypothetical LOC728844 (222040_at), score: 0.73 LOC730227hypothetical protein LOC730227 (215756_at), score: 0.6 LOC91316glucuronidase, beta/ immunoglobulin lambda-like polypeptide 1 pseudogene (215816_at), score: 0.78 LOC93432maltase-glucoamylase-like pseudogene (216666_at), score: 0.58 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: 0.53 LPAR4lysophosphatidic acid receptor 4 (206960_at), score: 0.61 LRP4low density lipoprotein receptor-related protein 4 (212850_s_at), score: 0.53 LRRC37B2leucine rich repeat containing 37, member B2 (216149_at), score: 0.52 LRRN2leucine rich repeat neuronal 2 (216164_at), score: 0.53 LRRTM4leucine rich repeat transmembrane neuronal 4 (220345_at), score: 0.64 LSM14BLSM14B, SCD6 homolog B (S. cerevisiae) (219653_at), score: 0.52 LY6Hlymphocyte antigen 6 complex, locus H (206773_at), score: 0.59 MAGI1membrane associated guanylate kinase, WW and PDZ domain containing 1 (206144_at), score: 0.52 MAGOH2mago-nashi homolog 2, proliferation-associated (Drosophila) (217692_at), score: 0.5 MAP2K7mitogen-activated protein kinase kinase 7 (216206_x_at), score: 0.63 MAP3K9mitogen-activated protein kinase kinase kinase 9 (213927_at), score: 0.79 MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1 (213013_at), score: 0.59 MASP2mannan-binding lectin serine peptidase 2 (207041_at), score: 0.64 MBmyoglobin (204179_at), score: 0.57 MCF2L2MCF.2 cell line derived transforming sequence-like 2 (215112_x_at), score: 0.61 MCL1myeloid cell leukemia sequence 1 (BCL2-related) (214057_at), score: 0.49 MCTP2multiple C2 domains, transmembrane 2 (220603_s_at), score: 0.48 MDM4Mdm4 p53 binding protein homolog (mouse) (205655_at), score: 0.61 MED9mediator complex subunit 9 (218372_at), score: 0.49 MEFVMediterranean fever (208262_x_at), score: 0.83 MEP1Bmeprin A, beta (207251_at), score: 0.79 METAP2methionyl aminopeptidase 2 (202015_x_at), score: 0.88 METTL7Amethyltransferase like 7A (211424_x_at), score: 0.92 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: 0.83 MFSD11major facilitator superfamily domain containing 11 (221192_x_at), score: 0.56 MGAT4Cmannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) (207447_s_at), score: 0.61 MGC5590hypothetical protein MGC5590 (220931_at), score: 0.49 MIA2melanoma inhibitory activity 2 (221177_at), score: 0.48 MLLT10myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (216506_x_at), score: 0.6 MMRN2multimerin 2 (219091_s_at), score: 0.82 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: 0.8 MOGmyelin oligodendrocyte glycoprotein (214650_x_at), score: 0.62 MPP3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) (206186_at), score: 0.53 MRPL44mitochondrial ribosomal protein L44 (218202_x_at), score: 0.58 MSL2male-specific lethal 2 homolog (Drosophila) (218733_at), score: 0.51 MSTP9macrophage stimulating, pseudogene 9 (213382_at), score: 0.77 MUC5ACmucin 5AC, oligomeric mucus/gel-forming (217182_at), score: 0.62 MYBPC1myosin binding protein C, slow type (214087_s_at), score: 0.59 MYCL1v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) (214058_at), score: 0.56 MYH15myosin, heavy chain 15 (215331_at), score: 0.66 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: 0.54 MYO1Amyosin IA (211916_s_at), score: 0.68 MYO5Cmyosin VC (218966_at), score: 0.59 N4BP3Nedd4 binding protein 3 (214775_at), score: 0.59 NACAnascent polypeptide-associated complex alpha subunit (222018_at), score: 0.57 NACA2nascent polypeptide-associated complex alpha subunit 2 (222224_at), score: 0.55 NCRNA00092non-protein coding RNA 92 (215861_at), score: 0.8 NCRNA00093non-protein coding RNA 93 (210723_x_at), score: 0.77 NHLH2nescient helix loop helix 2 (215228_at), score: 0.72 NINninein (GSK3B interacting protein) (219285_s_at), score: 0.48 NIPSNAP3Bnipsnap homolog 3B (C. elegans) (221104_s_at), score: 0.62 NOTCH4Notch homolog 4 (Drosophila) (205247_at), score: 0.53 NPIPL2nuclear pore complex interacting protein-like 2 (221992_at), score: 0.64 NPY2Rneuropeptide Y receptor Y2 (210730_s_at), score: 0.81 NRN1neuritin 1 (218625_at), score: 0.74 NTNG1netrin G1 (206713_at), score: 0.59 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: 0.72 NUCKS1nuclear casein kinase and cyclin-dependent kinase substrate 1 (222027_at), score: 0.6 OR2B2olfactory receptor, family 2, subfamily B, member 2 (216408_at), score: 0.65 OR2C1olfactory receptor, family 2, subfamily C, member 1 (221460_at), score: 0.49 OR2W1olfactory receptor, family 2, subfamily W, member 1 (221451_s_at), score: 0.59 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: 0.8 OVOL2ovo-like 2 (Drosophila) (211778_s_at), score: 0.65 P2RY4pyrimidinergic receptor P2Y, G-protein coupled, 4 (221466_at), score: 0.62 P2RY5purinergic receptor P2Y, G-protein coupled, 5 (218589_at), score: 0.49 PARP8poly (ADP-ribose) polymerase family, member 8 (219033_at), score: 0.56 PAX4paired box 4 (207867_at), score: 0.51 PBX2pre-B-cell leukemia homeobox 2 (202876_s_at), score: 0.64 PDE3Aphosphodiesterase 3A, cGMP-inhibited (206388_at), score: 0.53 PDE4Cphosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila) (206792_x_at), score: 0.59 PDE8Bphosphodiesterase 8B (213228_at), score: 0.57 PDZRN4PDZ domain containing ring finger 4 (220595_at), score: 0.58 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: 0.92 PEG3paternally expressed 3 (209242_at), score: 0.7 PELI2pellino homolog 2 (Drosophila) (219132_at), score: 0.5 PER2period homolog 2 (Drosophila) (205251_at), score: 0.51 PGCprogastricsin (pepsinogen C) (205261_at), score: 0.5 PGFplacental growth factor (215179_x_at), score: 0.52 PGK2phosphoglycerate kinase 2 (217009_at), score: 0.54 PGLYRP4peptidoglycan recognition protein 4 (220944_at), score: 0.51 PHC3polyhomeotic homolog 3 (Drosophila) (215521_at), score: 0.56 PHF20L1PHD finger protein 20-like 1 (222133_s_at), score: 0.53 PIP5K1Bphosphatidylinositol-4-phosphate 5-kinase, type I, beta (217477_at), score: 0.64 PIPOXpipecolic acid oxidase (221605_s_at), score: 0.6 PLA2G7phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (206214_at), score: 0.74 PLGLB1plasminogen-like B1 (214415_at), score: 0.48 PLUNCpalate, lung and nasal epithelium associated (220542_s_at), score: 0.49 PMP2peripheral myelin protein 2 (206826_at), score: 0.67 PNPLA2patatin-like phospholipase domain containing 2 (212705_x_at), score: 0.61 POGZpogo transposable element with ZNF domain (215281_x_at), score: 0.86 POM121L9PPOM121 membrane glycoprotein-like 9 (rat) pseudogene (222253_s_at), score: 0.64 PON1paraoxonase 1 (206344_at), score: 0.59 POU4F1POU class 4 homeobox 1 (206940_s_at), score: 0.72 PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha (219195_at), score: 0.79 PPP1R14Dprotein phosphatase 1, regulatory (inhibitor) subunit 14D (220082_at), score: 0.72 PPP4R4protein phosphatase 4, regulatory subunit 4 (220672_at), score: 0.49 PRB3proline-rich protein BstNI subfamily 3 (206998_x_at), score: 0.62 PRINSpsoriasis associated RNA induced by stress (non-protein coding) (216051_x_at), score: 1 PRKCBprotein kinase C, beta (209685_s_at), score: 0.53 PROL1proline rich, lacrimal 1 (208004_at), score: 0.71 PROX1prospero homeobox 1 (207401_at), score: 0.64 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: 0.66 PSG7pregnancy specific beta-1-glycoprotein 7 (205602_x_at), score: 0.49 PYHIN1pyrin and HIN domain family, member 1 (216748_at), score: 0.55 RAB26RAB26, member RAS oncogene family (50965_at), score: 0.77 RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4 (205651_x_at), score: 0.53 RASL11BRAS-like, family 11, member B (219142_at), score: 0.68 RBMX2RNA binding motif protein, X-linked 2 (204098_at), score: 0.58 RETret proto-oncogene (205879_x_at), score: 0.72 RGS10regulator of G-protein signaling 10 (214000_s_at), score: 0.53 RIMS2regulating synaptic membrane exocytosis 2 (215478_at), score: 0.73 RLN1relaxin 1 (211753_s_at), score: 0.68 ROS1c-ros oncogene 1 , receptor tyrosine kinase (207569_at), score: 0.53 RP11-35N6.1plasticity related gene 3 (219732_at), score: 0.77 RP3-377H14.5hypothetical LOC285830 (222279_at), score: 0.83 RP5-886K2.1neuronal thread protein AD7c-NTP (207953_at), score: 0.77 RPAINRPA interacting protein (216961_s_at), score: 0.55 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: 0.79 RPL21P37ribosomal protein L21 pseudogene 37 (216479_at), score: 0.82 RPL23AP32ribosomal protein L23a pseudogene 32 (207283_at), score: 0.77 RPL35Aribosomal protein L35a (215208_x_at), score: 0.8 RPL37Aribosomal protein L37a (214041_x_at), score: 0.69 RPLP2ribosomal protein, large, P2 (200908_s_at), score: 0.56 RPS10P3ribosomal protein S10 pseudogene 3 (217336_at), score: 0.52 RRHretinal pigment epithelium-derived rhodopsin homolog (208314_at), score: 0.69 RUNX3runt-related transcription factor 3 (204198_s_at), score: 0.48 RYR3ryanodine receptor 3 (206306_at), score: 0.51 S100A14S100 calcium binding protein A14 (218677_at), score: 0.59 SCARF1scavenger receptor class F, member 1 (206995_x_at), score: 0.91 SCD5stearoyl-CoA desaturase 5 (220232_at), score: 0.54 SCN10Asodium channel, voltage-gated, type X, alpha subunit (208578_at), score: 0.55 SCN11Asodium channel, voltage-gated, type XI, alpha subunit (220791_x_at), score: 0.74 SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (220574_at), score: 0.59 SERF1Bsmall EDRK-rich factor 1B (centromeric) (219982_s_at), score: 0.69 SERPINA7serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (206386_at), score: 0.81 SERPINB13serpin peptidase inhibitor, clade B (ovalbumin), member 13 (211362_s_at), score: 0.75 SFNstratifin (33322_i_at), score: 0.7 SFRS11splicing factor, arginine/serine-rich 11 (213742_at), score: 0.54 SFTPBsurfactant protein B (214354_x_at), score: 0.85 SH3BP2SH3-domain binding protein 2 (217257_at), score: 0.83 SH3GL3SH3-domain GRB2-like 3 (211565_at), score: 0.52 SHOX2short stature homeobox 2 (210135_s_at), score: 0.61 SIRPB1signal-regulatory protein beta 1 (206934_at), score: 0.69 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (207185_at), score: 0.81 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (207095_at), score: 0.69 SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (217473_x_at), score: 0.61 SLC12A3solute carrier family 12 (sodium/chloride transporters), member 3 (215274_at), score: 0.73 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: 0.83 SLC17A6solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 (220551_at), score: 0.77 SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2 (208389_s_at), score: 0.49 SLC1A7solute carrier family 1 (glutamate transporter), member 7 (210923_at), score: 0.63 SLC26A10solute carrier family 26, member 10 (214951_at), score: 0.62 SLC26A4solute carrier family 26, member 4 (206529_x_at), score: 0.49 SLC4A5solute carrier family 4, sodium bicarbonate cotransporter, member 5 (204296_at), score: 0.61 SLC6A14solute carrier family 6 (amino acid transporter), member 14 (219795_at), score: 0.74 SLCO1A2solute carrier organic anion transporter family, member 1A2 (207308_at), score: 0.51 SLCO1C1solute carrier organic anion transporter family, member 1C1 (220460_at), score: 0.67 SP140SP140 nuclear body protein (207777_s_at), score: 0.67 SPAM1sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) (216989_at), score: 0.57 SPARCL1SPARC-like 1 (hevin) (200795_at), score: 0.56 SPINLW1serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin) (206318_at), score: 0.71 SPNsialophorin (206057_x_at), score: 0.62 SPRY1sprouty homolog 1, antagonist of FGF signaling (Drosophila) (212558_at), score: 0.66 SPTLC3serine palmitoyltransferase, long chain base subunit 3 (220456_at), score: 0.88 ST3GAL2ST3 beta-galactoside alpha-2,3-sialyltransferase 2 (217650_x_at), score: 0.49 ST8SIA3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 (208064_s_at), score: 0.61 STAP2signal transducing adaptor family member 2 (221610_s_at), score: 0.64 SYCP1synaptonemal complex protein 1 (206740_x_at), score: 0.77 SYN2synapsin II (210247_at), score: 0.49 TAAR2trace amine associated receptor 2 (221394_at), score: 0.76 TAC1tachykinin, precursor 1 (206552_s_at), score: 0.61 TACR1tachykinin receptor 1 (208048_at), score: 0.85 TAS2R16taste receptor, type 2, member 16 (221444_at), score: 0.83 TAS2R9taste receptor, type 2, member 9 (221461_at), score: 0.73 TATtyrosine aminotransferase (206916_x_at), score: 0.59 TBX21T-box 21 (220684_at), score: 0.68 TBX6T-box 6 (207684_at), score: 0.88 TGM4transglutaminase 4 (prostate) (217566_s_at), score: 0.61 TIMM8Atranslocase of inner mitochondrial membrane 8 homolog A (yeast) (210800_at), score: 0.73 TLR1toll-like receptor 1 (210176_at), score: 0.53 TMCC2transmembrane and coiled-coil domain family 2 (213096_at), score: 0.51 TMEM100transmembrane protein 100 (219230_at), score: 0.57 TMEM19transmembrane protein 19 (219941_at), score: 0.54 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: 0.71 TNFRSF9tumor necrosis factor receptor superfamily, member 9 (207536_s_at), score: 0.57 TP53TG3TP53 target 3 (220167_s_at), score: 0.84 TP63tumor protein p63 (209863_s_at), score: 0.75 TPTEtransmembrane phosphatase with tensin homology (220205_at), score: 0.76 TRA@T cell receptor alpha locus (216540_at), score: 0.89 TRIM36tripartite motif-containing 36 (219736_at), score: 0.74 TRIM45tripartite motif-containing 45 (219923_at), score: 0.66 TRPM3transient receptor potential cation channel, subfamily M, member 3 (220463_at), score: 0.61 TRPV1transient receptor potential cation channel, subfamily V, member 1 (219632_s_at), score: 0.7 TSHBthyroid stimulating hormone, beta (214529_at), score: 0.55 TSPAN15tetraspanin 15 (218693_at), score: 0.51 TSPY1testis specific protein, Y-linked 1 (216374_at), score: 0.53 TUBA3Ctubulin, alpha 3c (210527_x_at), score: 0.7 TULP2tubby like protein 2 (206733_at), score: 0.55 UBQLN4ubiquilin 4 (222252_x_at), score: 0.54 UGT1A8UDP glucuronosyltransferase 1 family, polypeptide A8 (221304_at), score: 0.5 UGT2B28UDP glucuronosyltransferase 2 family, polypeptide B28 (211682_x_at), score: 0.94 USP6ubiquitin specific peptidase 6 (Tre-2 oncogene) (206405_x_at), score: 0.79 UTF1undifferentiated embryonic cell transcription factor 1 (208275_x_at), score: 0.66 VAMP8vesicle-associated membrane protein 8 (endobrevin) (202546_at), score: 0.55 VEZTvezatin, adherens junctions transmembrane protein (207263_x_at), score: 0.77 VGFVGF nerve growth factor inducible (205586_x_at), score: 0.64 WDR78WD repeat domain 78 (220769_s_at), score: 0.54 WNT6wingless-type MMTV integration site family, member 6 (71933_at), score: 0.72 XISTX (inactive)-specific transcript (non-protein coding) (214218_s_at), score: 0.5 XRCC2X-ray repair complementing defective repair in Chinese hamster cells 2 (207598_x_at), score: 0.51 ZBTB39zinc finger and BTB domain containing 39 (205256_at), score: 0.61 ZC3H7Bzinc finger CCCH-type containing 7B (206169_x_at), score: 0.72 ZIC1Zic family member 1 (odd-paired homolog, Drosophila) (206373_at), score: 0.62 ZNF117zinc finger protein 117 (207605_x_at), score: 0.78 ZNF160zinc finger protein 160 (214715_x_at), score: 0.62 ZNF280Azinc finger protein 280A (216034_at), score: 0.54 ZNF287zinc finger protein 287 (216453_at), score: 0.53 ZNF335zinc finger protein 335 (78330_at), score: 0.51 ZNF440zinc finger protein 440 (215892_at), score: 0.83 ZNF492zinc finger protein 492 (215532_x_at), score: 0.67 ZNF493zinc finger protein 493 (211064_at), score: 0.75 ZNF589zinc finger protein 589 (210062_s_at), score: 0.55 ZNF639zinc finger protein 639 (218413_s_at), score: 0.57 ZNF701zinc finger protein 701 (220242_x_at), score: 0.59 ZNF770zinc finger protein 770 (220608_s_at), score: 0.53 ZNF816Azinc finger protein 816A (217541_x_at), score: 0.79 ZPBPzona pellucida binding protein (207021_at), score: 0.74 ZSCAN12zinc finger and SCAN domain containing 12 (206507_at), score: 0.51

Non-Entrez genes

206507_atUnknown, score: 0.72 205256_atUnknown, score: 0.74 213096_atUnknown, score: 0.66 214798_atUnknown, score: 0.48 219697_atUnknown, score: 0.77

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
E-TABM-263-raw-cel-1515485651.cel	1	6	Cycle	hgu133a2	none	Cycle 1
46A.CEL	1	3	DS-mosaic	hgu133plus2	none	DS-mosaic 1
t21d 08-03.CEL	7	1	DS-CC	hgu133a	Down	DS-CC 7
2Twin.CEL	2	2	DS-twin	hgu133plus2	none	DS-twin 2
E-GEOD-3407-raw-cel-1437949557.cel	1	4	Cockayne	hgu133a	CS	eGFP
ctrl a 08-03.CEL	1	1	DS-CC	hgu133a	none	DS-CC 1
t21a 08-03.CEL	4	1	DS-CC	hgu133a	Down	DS-CC 4
E-GEOD-4219-raw-cel-1311956083.cel	2	7	Sph-mono	hgu133plus2	none	Sph-mon 1