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Expression data for module #1076

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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DNA replication

The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.

skeletal system development

The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).

ossification

The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.

angiogenesis

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

blood vessel development

The process whose specific outcome is the progression of the blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.

osteoblast differentiation

The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, the mesodermal cell that gives rise to bone.

cell activation

A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.

vasculature development

The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

circulatory system process

A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

cellular alcohol metabolic process

The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

DNA metabolic process

The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

transcription

The synthesis of either RNA on a template of DNA or DNA on a template of RNA.

transcription, DNA-dependent

The synthesis of RNA on a template of DNA.

transcription from RNA polymerase II promoter

The synthesis of RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).

lipid metabolic process

The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

steroid biosynthetic process

The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.

cell motion

Any process involved in the controlled movement of a cell.

chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

intracellular signaling cascade

A series of reactions within the cell that occur as a result of a single trigger reaction or compound.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

behavior

The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

locomotory behavior

The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

blood circulation

The flow of blood through the body of an animal, enabling the transport of O2 and nutrients to the tissues and the removal of waste products.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

cholesterol metabolic process

The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

biosynthetic process

The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

response to external stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

gene expression

The process by which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.

RNA metabolic process

The chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

sterol metabolic process

The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

sterol biosynthetic process

The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

cell migration

The orderly movement of cells from one site to another, often during the development of a multicellular organism or multicellular structure.

second-messenger-mediated signaling

A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell.

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

RNA biosynthetic process

The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

locomotion

Self-propelled movement of a cell or organism from one location to another.

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

muscle cell differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a muscle cell.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.

biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

regulation of cell differentiation

Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.

positive regulation of cell differentiation

Any process that activates or increases the frequency, rate or extent of cell differentiation.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

blood vessel morphogenesis

The process by which the anatomical structures of blood vessels are generated and organized. Morphogenesis pertains to the creation of form. The blood vessel is the vasculature carrying blood.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

anatomical structure formation

The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

tissue remodeling

The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of developmental process

Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of muscle cell differentiation

Any process that modulates the frequency, rate or extent of muscle cell differentiation.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

positive regulation of cell motion

Any process that activates or increases the frequency, rate or extent of the movement of a cell.

localization of cell

Any process by which a cell is transported to, and/or maintained in, a specific location.

bone development

The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

positive regulation of developmental process

Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

positive regulation of cell motion

Any process that activates or increases the frequency, rate or extent of the movement of a cell.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

anatomical structure formation

The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

regulation of cell differentiation

Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.

positive regulation of developmental process

Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

positive regulation of cell differentiation

Any process that activates or increases the frequency, rate or extent of cell differentiation.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

cell motion

Any process involved in the controlled movement of a cell.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

transcription

The synthesis of either RNA on a template of DNA or DNA on a template of RNA.

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

positive regulation of cell motion

Any process that activates or increases the frequency, rate or extent of the movement of a cell.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

osteoblast differentiation

The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, the mesodermal cell that gives rise to bone.

regulation of cell differentiation

Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.

positive regulation of cell differentiation

Any process that activates or increases the frequency, rate or extent of cell differentiation.

positive regulation of cell differentiation

Any process that activates or increases the frequency, rate or extent of cell differentiation.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

ossification

The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

steroid biosynthetic process

The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.

sterol metabolic process

The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

transcription, DNA-dependent

The synthesis of RNA on a template of DNA.

DNA metabolic process

The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

RNA metabolic process

The chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

sterol biosynthetic process

The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

RNA biosynthetic process

The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers.

regulation of muscle cell differentiation

Any process that modulates the frequency, rate or extent of muscle cell differentiation.

bone development

The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.

angiogenesis

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.

DNA replication

The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.

transcription

The synthesis of either RNA on a template of DNA or DNA on a template of RNA.

blood vessel morphogenesis

The process by which the anatomical structures of blood vessels are generated and organized. Morphogenesis pertains to the creation of form. The blood vessel is the vasculature carrying blood.

Help | Hide | Top The GO tree — Cellular Components

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extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

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protein binding

Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

G-protein-coupled receptor binding

Interacting selectively with a G-protein-coupled receptor.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

nucleic acid binding

Interacting selectively with any nucleic acid.

DNA binding

Interacting selectively with DNA (deoxyribonucleic acid).

transcription factor activity

The function of binding to a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.

receptor binding

Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

cytokine activity

Functions to control the survival, growth, differentiation and effector function of tissues and cells.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

chemokine activity

The function of a family of chemotactic pro-inflammatory activation-inducible cytokines acting primarily upon hemopoietic cells in immunoregulatory processes; all chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation.

growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.

transcription repressor activity

Any transcription regulator activity that prevents or downregulates transcription.

transcription regulator activity

Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.

chemokine receptor binding

Interacting selectively with any chemokine receptor.

all

This term is the most general term possible

transcription factor activity

The function of binding to a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.

chemokine activity

The function of a family of chemotactic pro-inflammatory activation-inducible cytokines acting primarily upon hemopoietic cells in immunoregulatory processes; all chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation.

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04060 4.768e-05 7.016 23
115 Cytokine-cytokine receptor interaction
00100 4.165e-03 1.403 8
23 Biosynthesis of steroids
04610 3.558e-02 2.013 8
33 Complement and coagulation cascades

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide (209612_s_at), score: 0.46 ADIPOR2adiponectin receptor 2 (201346_at), score: 0.46 ADMadrenomedullin (202912_at), score: -0.87 ADRA2Aadrenergic, alpha-2A-, receptor (209869_at), score: 0.52 AJAP1adherens junctions associated protein 1 (206460_at), score: 0.36 ALDH6A1aldehyde dehydrogenase 6 family, member A1 (221589_s_at), score: 0.31 ALDOCaldolase C, fructose-bisphosphate (202022_at), score: 0.38 ANGPTL4angiopoietin-like 4 (221009_s_at), score: 1 ANK2ankyrin 2, neuronal (202920_at), score: 0.62 AQP3aquaporin 3 (Gill blood group) (39248_at), score: 0.55 AREGamphiregulin (205239_at), score: 0.41 ARID5AAT rich interactive domain 5A (MRF1-like) (213138_at), score: 0.58 ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila) (219918_s_at), score: -0.87 ATF3activating transcription factor 3 (202672_s_at), score: 0.36 ATP13A3ATPase type 13A3 (219558_at), score: 0.52 ATP2A2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (212361_s_at), score: 0.36 ATP6V0A1ATPase, H+ transporting, lysosomal V0 subunit a1 (205095_s_at), score: 0.34 B3GNT2UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (219326_s_at), score: 0.61 B4GALT5UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (221484_at), score: 0.41 BBS1Bardet-Biedl syndrome 1 (218471_s_at), score: 0.38 BCL7AB-cell CLL/lymphoma 7A (203795_s_at), score: 0.53 BHLHE40basic helix-loop-helix family, member e40 (201170_s_at), score: 0.55 BIRC3baculoviral IAP repeat-containing 3 (210538_s_at), score: 0.32 BIRC5baculoviral IAP repeat-containing 5 (202095_s_at), score: -0.86 BMP2bone morphogenetic protein 2 (205289_at), score: 0.63 BMP6bone morphogenetic protein 6 (206176_at), score: 0.43 BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) (210214_s_at), score: 0.5 BTN3A1butyrophilin, subfamily 3, member A1 (209770_at), score: 0.32 C11orf75chromosome 11 open reading frame 75 (219806_s_at), score: 0.31 C14orf1chromosome 14 open reading frame 1 (217188_s_at), score: 0.38 C17orf91chromosome 17 open reading frame 91 (214696_at), score: 0.62 C19orf28chromosome 19 open reading frame 28 (220178_at), score: 0.43 C1orf56chromosome 1 open reading frame 56 (221222_s_at), score: 0.33 C1Rcomplement component 1, r subcomponent (212067_s_at), score: 0.61 C1RLcomplement component 1, r subcomponent-like (218983_at), score: 0.41 C1Scomplement component 1, s subcomponent (208747_s_at), score: 0.47 C21orf45chromosome 21 open reading frame 45 (219004_s_at), score: -0.85 C3orf52chromosome 3 open reading frame 52 (219474_at), score: 0.37 C4orf18chromosome 4 open reading frame 18 (219872_at), score: 0.58 C6orf145chromosome 6 open reading frame 145 (212923_s_at), score: 0.44 CADPS2Ca++-dependent secretion activator 2 (219572_at), score: 0.34 CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (211368_s_at), score: 0.39 CBFBcore-binding factor, beta subunit (206788_s_at), score: 0.43 CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b (209682_at), score: 0.42 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: 0.67 CCL7chemokine (C-C motif) ligand 7 (208075_s_at), score: 0.49 CCNE2cyclin E2 (205034_at), score: -0.85 CCNJcyclin J (219470_x_at), score: 0.43 CCRL1chemokine (C-C motif) receptor-like 1 (220351_at), score: 0.31 CD200CD200 molecule (209583_s_at), score: 0.34 CD302CD302 molecule (203799_at), score: 0.54 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: 0.4 CDC42SE1CDC42 small effector 1 (218157_x_at), score: 0.3 CDK2cyclin-dependent kinase 2 (204252_at), score: -0.89 CDV3CDV3 homolog (mouse) (213548_s_at), score: 0.32 CDYLchromodomain protein, Y-like (203100_s_at), score: 0.39 CENPMcentromere protein M (218741_at), score: -0.89 CHAF1Achromatin assembly factor 1, subunit A (p150) (214426_x_at), score: -0.85 CHAF1Bchromatin assembly factor 1, subunit B (p60) (204775_at), score: -0.85 CHIC2cysteine-rich hydrophobic domain 2 (219492_at), score: 0.32 CHMP1Bchromatin modifying protein 1B (218178_s_at), score: 0.36 CHST2carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 (203921_at), score: 0.43 CHST3carbohydrate (chondroitin 6) sulfotransferase 3 (209834_at), score: 0.35 CKAP2cytoskeleton associated protein 2 (218252_at), score: -0.94 CLCF1cardiotrophin-like cytokine factor 1 (219500_at), score: 0.46 CLUclusterin (208791_at), score: 0.46 COL14A1collagen, type XIV, alpha 1 (212865_s_at), score: 0.44 COL15A1collagen, type XV, alpha 1 (203477_at), score: 0.76 CORINcorin, serine peptidase (220356_at), score: 0.39 CPA3carboxypeptidase A3 (mast cell) (205624_at), score: 0.52 CREG1cellular repressor of E1A-stimulated genes 1 (201200_at), score: 0.56 CRISPLD2cysteine-rich secretory protein LCCL domain containing 2 (221541_at), score: 0.5 CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 2 (222235_s_at), score: 0.37 CSRNP2cysteine-serine-rich nuclear protein 2 (221260_s_at), score: 0.41 CST3cystatin C (201360_at), score: 0.31 CTSDcathepsin D (200766_at), score: 0.42 CTSFcathepsin F (203657_s_at), score: 0.33 CTSOcathepsin O (203758_at), score: 0.41 CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (204470_at), score: 0.35 CXCL2chemokine (C-X-C motif) ligand 2 (209774_x_at), score: 0.37 CXCL3chemokine (C-X-C motif) ligand 3 (207850_at), score: 0.62 CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) (206336_at), score: 0.39 CXCR7chemokine (C-X-C motif) receptor 7 (212977_at), score: 0.52 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: 0.6 DAAM2dishevelled associated activator of morphogenesis 2 (212793_at), score: 0.34 DACT1dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) (219179_at), score: 0.36 DCNdecorin (211896_s_at), score: 0.41 DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae) (218508_at), score: 0.44 DDX11DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (208149_x_at), score: -0.85 DDX3YDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked (205000_at), score: 0.35 DEKDEK oncogene (200934_at), score: -0.89 DEPDC1DEP domain containing 1 (220295_x_at), score: -0.85 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: 0.42 DHCR77-dehydrocholesterol reductase (201790_s_at), score: 0.49 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: 0.67 DLGAP5discs, large (Drosophila) homolog-associated protein 5 (203764_at), score: -0.85 DNAJC9DnaJ (Hsp40) homolog, subfamily C, member 9 (213088_s_at), score: -0.87 DNASE2deoxyribonuclease II, lysosomal (214992_s_at), score: 0.46 DOCK9dedicator of cytokinesis 9 (212538_at), score: 0.47 DPP4dipeptidyl-peptidase 4 (211478_s_at), score: 0.6 DRAMdamage-regulated autophagy modulator (218627_at), score: 0.5 DTLdenticleless homolog (Drosophila) (218585_s_at), score: -0.86 DUSP3dual specificity phosphatase 3 (201536_at), score: 0.31 DUSP5dual specificity phosphatase 5 (209457_at), score: 0.57 DVL3dishevelled, dsh homolog 3 (Drosophila) (201908_at), score: 0.32 EDN1endothelin 1 (218995_s_at), score: 0.37 EFHD1EF-hand domain family, member D1 (209343_at), score: 0.31 EGR2early growth response 2 (Krox-20 homolog, Drosophila) (205249_at), score: 0.64 EGR3early growth response 3 (206115_at), score: 0.66 EIF2C2eukaryotic translation initiation factor 2C, 2 (213310_at), score: 0.37 ENTPD7ectonucleoside triphosphate diphosphohydrolase 7 (220153_at), score: 0.63 EPHA2EPH receptor A2 (203499_at), score: 0.33 ERAP1endoplasmic reticulum aminopeptidase 1 (214012_at), score: 0.51 ERCC6Lexcision repair cross-complementing rodent repair deficiency, complementation group 6-like (219650_at), score: -0.85 EREGepiregulin (205767_at), score: 0.35 F10coagulation factor X (205620_at), score: 0.65 F3coagulation factor III (thromboplastin, tissue factor) (204363_at), score: 0.51 FABP3fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) (214285_at), score: 0.38 FAM108B1family with sequence similarity 108, member B1 (220285_at), score: 0.39 FANCGFanconi anemia, complementation group G (203564_at), score: -0.87 FASTKD5FAST kinase domains 5 (219016_at), score: 0.36 FBXW7F-box and WD repeat domain containing 7 (218751_s_at), score: 0.69 FCGRTFc fragment of IgG, receptor, transporter, alpha (218831_s_at), score: 0.48 FEM1Bfem-1 homolog b (C. elegans) (212367_at), score: 0.5 FGF1fibroblast growth factor 1 (acidic) (205117_at), score: 0.66 FGF2fibroblast growth factor 2 (basic) (204421_s_at), score: 0.38 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: 0.73 FHL3four and a half LIM domains 3 (218818_at), score: 0.36 FHOD1formin homology 2 domain containing 1 (218530_at), score: 0.36 FILIP1Lfilamin A interacting protein 1-like (204135_at), score: 0.33 FOSBFBJ murine osteosarcoma viral oncogene homolog B (202768_at), score: 0.95 FOXO3forkhead box O3 (204132_s_at), score: 0.5 FRYfurry homolog (Drosophila) (204072_s_at), score: 0.33 GAAglucosidase, alpha; acid (202812_at), score: 0.48 GABARAPL1GABA(A) receptor-associated protein like 1 (208868_s_at), score: 0.47 GADD45Agrowth arrest and DNA-damage-inducible, alpha (203725_at), score: 0.33 GALNAC4S-6STB cell RAG associated protein (203066_at), score: 0.41 GCH1GTP cyclohydrolase 1 (204224_s_at), score: 0.62 GDF15growth differentiation factor 15 (221577_x_at), score: 0.3 GDPD5glycerophosphodiester phosphodiesterase domain containing 5 (32502_at), score: 0.31 GEMGTP binding protein overexpressed in skeletal muscle (204472_at), score: 0.8 GFPT2glutamine-fructose-6-phosphate transaminase 2 (205100_at), score: 0.59 GINS1GINS complex subunit 1 (Psf1 homolog) (206102_at), score: -0.91 GINS2GINS complex subunit 2 (Psf2 homolog) (221521_s_at), score: -0.89 GMNNgeminin, DNA replication inhibitor (218350_s_at), score: -0.87 GNPTABN-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (212959_s_at), score: 0.47 GPNMBglycoprotein (transmembrane) nmb (201141_at), score: 0.57 GPR183G protein-coupled receptor 183 (205419_at), score: 0.63 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: 0.45 GRAMD3GRAM domain containing 3 (218706_s_at), score: 0.31 GRNgranulin (211284_s_at), score: 0.4 GSTM1glutathione S-transferase mu 1 (204550_x_at), score: 0.54 GSTM2glutathione S-transferase mu 2 (muscle) (204418_x_at), score: 0.33 HBEGFheparin-binding EGF-like growth factor (203821_at), score: 0.85 HHLA3HERV-H LTR-associating 3 (220387_s_at), score: 0.36 HIPK3homeodomain interacting protein kinase 3 (210148_at), score: 0.56 HIVEP1human immunodeficiency virus type I enhancer binding protein 1 (204512_at), score: 0.7 HIVEP2human immunodeficiency virus type I enhancer binding protein 2 (212642_s_at), score: 0.52 HK2hexokinase 2 (202934_at), score: 0.5 HLA-Cmajor histocompatibility complex, class I, C (211799_x_at), score: 0.43 HLA-Emajor histocompatibility complex, class I, E (200904_at), score: 0.39 HLA-Fmajor histocompatibility complex, class I, F (204806_x_at), score: 0.38 HLXH2.0-like homeobox (214438_at), score: 0.64 HMGB2high-mobility group box 2 (208808_s_at), score: -0.97 HMGCR3-hydroxy-3-methylglutaryl-Coenzyme A reductase (202539_s_at), score: 0.31 HMGCS13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) (221750_at), score: 0.48 HMGN1high-mobility group nucleosome binding domain 1 (200944_s_at), score: -0.86 HMGN2high-mobility group nucleosomal binding domain 2 (208668_x_at), score: -0.89 HMOX1heme oxygenase (decycling) 1 (203665_at), score: 0.57 HNMThistamine N-methyltransferase (204112_s_at), score: 0.31 HOMER1homer homolog 1 (Drosophila) (213793_s_at), score: 0.33 HOXA10homeobox A10 (213150_at), score: -0.85 HSPA12Aheat shock 70kDa protein 12A (214434_at), score: 0.32 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: 0.49 ICAM1intercellular adhesion molecule 1 (202638_s_at), score: 0.77 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: 0.57 IDI2isopentenyl-diphosphate delta isomerase 2 (217631_at), score: 0.39 IDUAiduronidase, alpha-L- (205059_s_at), score: 0.32 IL11interleukin 11 (206924_at), score: 0.71 IL1RAPinterleukin 1 receptor accessory protein (205227_at), score: 0.62 IL1RL1interleukin 1 receptor-like 1 (207526_s_at), score: 0.58 IL23Ainterleukin 23, alpha subunit p19 (211796_s_at), score: 0.34 IL6interleukin 6 (interferon, beta 2) (205207_at), score: 0.89 IL8interleukin 8 (211506_s_at), score: 0.79 INHBAinhibin, beta A (210511_s_at), score: 0.42 INSIG1insulin induced gene 1 (201627_s_at), score: 0.74 ITGA1integrin, alpha 1 (214660_at), score: 0.5 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: 0.61 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (221778_at), score: 0.78 JMJD3jumonji domain containing 3, histone lysine demethylase (213146_at), score: 0.89 JMJD6jumonji domain containing 6 (212722_s_at), score: 0.55 JUNBjun B proto-oncogene (201473_at), score: 0.49 JUNDjun D proto-oncogene (203751_x_at), score: 0.64 KCTD13potassium channel tetramerisation domain containing 13 (45653_at), score: 0.33 KIAA0247KIAA0247 (202181_at), score: 0.6 KIAA1024KIAA1024 (215081_at), score: 0.4 KIAA1644KIAA1644 (52837_at), score: 0.52 KIF11kinesin family member 11 (204444_at), score: -0.86 KIF20Bkinesin family member 20B (205235_s_at), score: -0.85 KIF22kinesin family member 22 (202183_s_at), score: -0.87 KLHL21kelch-like 21 (Drosophila) (203068_at), score: 0.49 KLHL26kelch-like 26 (Drosophila) (219354_at), score: 0.34 LAMA5laminin, alpha 5 (210150_s_at), score: 0.34 LDLRlow density lipoprotein receptor (202068_s_at), score: 0.47 LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein (200923_at), score: 0.37 LHFPlipoma HMGIC fusion partner (218656_s_at), score: 0.41 LIFleukemia inhibitory factor (cholinergic differentiation factor) (205266_at), score: 0.89 LIMS1LIM and senescent cell antigen-like domains 1 (207198_s_at), score: 0.39 LITAFlipopolysaccharide-induced TNF factor (200706_s_at), score: 0.32 LMBRD1LMBR1 domain containing 1 (218191_s_at), score: 0.35 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: 0.84 LMNB1lamin B1 (203276_at), score: -0.86 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: 0.6 LRIG1leucine-rich repeats and immunoglobulin-like domains 1 (211596_s_at), score: 0.57 LRP1low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) (200785_s_at), score: 0.32 LRRFIP1leucine rich repeat (in FLII) interacting protein 1 (201861_s_at), score: 0.33 LTBRlymphotoxin beta receptor (TNFR superfamily, member 3) (203005_at), score: 0.32 LUZP1leucine zipper protein 1 (221832_s_at), score: 0.39 MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast) (203362_s_at), score: -0.97 MAFv-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) (209348_s_at), score: 0.34 MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) (36711_at), score: 0.35 MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 (209737_at), score: 0.41 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: 0.67 MAP1Smicrotubule-associated protein 1S (218522_s_at), score: 0.33 MAP2K3mitogen-activated protein kinase kinase 3 (207667_s_at), score: 0.72 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: 0.36 MAP3K4mitogen-activated protein kinase kinase kinase 4 (216199_s_at), score: 0.52 MARCH2membrane-associated ring finger (C3HC4) 2 (210075_at), score: 0.32 MAT2Amethionine adenosyltransferase II, alpha (200769_s_at), score: 0.32 MAXMYC associated factor X (210734_x_at), score: 0.35 MCM2minichromosome maintenance complex component 2 (202107_s_at), score: -0.88 MCM5minichromosome maintenance complex component 5 (216237_s_at), score: -0.9 MEIS1Meis homeobox 1 (204069_at), score: 0.31 MEIS3P1Meis homeobox 3 pseudogene 1 (214077_x_at), score: 0.45 MFAP4microfibrillar-associated protein 4 (212713_at), score: 0.68 MLXIPMLX interacting protein (202519_at), score: 0.41 MSCmusculin (activated B-cell factor-1) (209928_s_at), score: 0.54 MSX1msh homeobox 1 (205932_s_at), score: 0.34 MTSS1metastasis suppressor 1 (203037_s_at), score: 0.69 MYCv-myc myelocytomatosis viral oncogene homolog (avian) (202431_s_at), score: 0.38 MYO1Dmyosin ID (212338_at), score: 0.45 MYO1Emyosin IE (203072_at), score: 0.31 NAB1NGFI-A binding protein 1 (EGR1 binding protein 1) (208047_s_at), score: 0.46 NADSYN1NAD synthetase 1 (218840_s_at), score: 0.31 NAMPTnicotinamide phosphoribosyltransferase (217738_at), score: 0.57 NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae) (204162_at), score: -0.86 NDRG1N-myc downstream regulated 1 (200632_s_at), score: 0.3 NEDD9neural precursor cell expressed, developmentally down-regulated 9 (202149_at), score: 0.52 NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (210162_s_at), score: 0.92 NFIL3nuclear factor, interleukin 3 regulated (203574_at), score: 0.62 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: 0.72 NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (207535_s_at), score: 0.47 NID1nidogen 1 (202008_s_at), score: 0.35 NINJ1ninjurin 1 (203045_at), score: 0.61 NPnucleoside phosphorylase (201695_s_at), score: 0.39 NPC1Niemann-Pick disease, type C1 (202679_at), score: 0.35 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: 0.58 NR4A1nuclear receptor subfamily 4, group A, member 1 (202340_x_at), score: 0.73 NR4A2nuclear receptor subfamily 4, group A, member 2 (216248_s_at), score: 0.42 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: 0.9 NUP107nucleoporin 107kDa (218768_at), score: -0.84 NUSAP1nucleolar and spindle associated protein 1 (218039_at), score: -0.87 OLFML2Aolfactomedin-like 2A (213075_at), score: 0.47 ORC6Lorigin recognition complex, subunit 6 like (yeast) (219105_x_at), score: -0.88 OSMRoncostatin M receptor (205729_at), score: 0.45 P2RX4purinergic receptor P2X, ligand-gated ion channel, 4 (204088_at), score: 0.37 PANX1pannexin 1 (204715_at), score: 0.49 PARP2poly (ADP-ribose) polymerase 2 (214086_s_at), score: -0.85 PCTK2PCTAIRE protein kinase 2 (221918_at), score: 0.36 PDGFAplatelet-derived growth factor alpha polypeptide (205463_s_at), score: 0.69 PDGFDplatelet derived growth factor D (219304_s_at), score: 0.71 PDGFRBplatelet-derived growth factor receptor, beta polypeptide (202273_at), score: 0.37 PDGFRLplatelet-derived growth factor receptor-like (205226_at), score: 0.44 PDLIM3PDZ and LIM domain 3 (209621_s_at), score: 0.42 PDLIM4PDZ and LIM domain 4 (211564_s_at), score: 0.3 PGCPplasma glutamate carboxypeptidase (203501_at), score: 0.3 PHLDA3pleckstrin homology-like domain, family A, member 3 (218634_at), score: 0.34 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (203879_at), score: 0.61 PIONpigeon homolog (Drosophila) (222150_s_at), score: 0.31 PIP5K1Aphosphatidylinositol-4-phosphate 5-kinase, type I, alpha (211205_x_at), score: 0.32 PLAURplasminogen activator, urokinase receptor (211924_s_at), score: 0.5 PLCXD1phosphatidylinositol-specific phospholipase C, X domain containing 1 (218951_s_at), score: 0.35 PLK3polo-like kinase 3 (Drosophila) (204958_at), score: 0.5 PLSCR4phospholipid scramblase 4 (218901_at), score: 0.52 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: 1 POLA1polymerase (DNA directed), alpha 1, catalytic subunit (204835_at), score: -0.84 POLA2polymerase (DNA directed), alpha 2 (70kD subunit) (204441_s_at), score: -0.85 POLD1polymerase (DNA directed), delta 1, catalytic subunit 125kDa (203422_at), score: -0.87 POLR1Cpolymerase (RNA) I polypeptide C, 30kDa (207515_s_at), score: 0.5 PPAP2Aphosphatidic acid phosphatase type 2A (209147_s_at), score: 0.33 PPARDperoxisome proliferator-activated receptor delta (37152_at), score: 0.49 PPLperiplakin (203407_at), score: 0.65 PRELPproline/arginine-rich end leucine-rich repeat protein (204223_at), score: 0.39 PRKCDprotein kinase C, delta (202545_at), score: 0.32 PRKG1protein kinase, cGMP-dependent, type I (207119_at), score: 0.35 PROS1protein S (alpha) (207808_s_at), score: 0.41 PRR11proline rich 11 (219392_x_at), score: -0.89 PSAPprosaposin (200866_s_at), score: 0.3 PSMC3IPPSMC3 interacting protein (213951_s_at), score: -0.87 PTGDSprostaglandin D2 synthase 21kDa (brain) (212187_x_at), score: 0.5 PTHLHparathyroid hormone-like hormone (211756_at), score: 0.48 PTPN12protein tyrosine phosphatase, non-receptor type 12 (216915_s_at), score: 0.33 PTPREprotein tyrosine phosphatase, receptor type, E (221840_at), score: 0.51 PTTG1pituitary tumor-transforming 1 (203554_x_at), score: -0.84 RAB33ARAB33A, member RAS oncogene family (206039_at), score: 0.4 RABL2ARAB, member of RAS oncogene family-like 2A (220500_s_at), score: 0.3 RACGAP1Rac GTPase activating protein 1 (222077_s_at), score: -0.87 RAD51AP1RAD51 associated protein 1 (204146_at), score: -0.86 RAD9ARAD9 homolog A (S. pombe) (204828_at), score: -0.84 RAMP1receptor (G protein-coupled) activity modifying protein 1 (204916_at), score: 0.4 RANBP2RAN binding protein 2 (201711_x_at), score: 0.45 RAPGEF2Rap guanine nucleotide exchange factor (GEF) 2 (203097_s_at), score: 0.32 RBMS1RNA binding motif, single stranded interacting protein 1 (209868_s_at), score: 0.33 RCAN1regulator of calcineurin 1 (215253_s_at), score: 0.3 RCAN2regulator of calcineurin 2 (203498_at), score: 0.55 RCL1RNA terminal phosphate cyclase-like 1 (218544_s_at), score: 0.54 RELv-rel reticuloendotheliosis viral oncogene homolog (avian) (206036_s_at), score: 0.32 RELBv-rel reticuloendotheliosis viral oncogene homolog B (205205_at), score: 0.54 RFC4replication factor C (activator 1) 4, 37kDa (204023_at), score: -0.89 RFC5replication factor C (activator 1) 5, 36.5kDa (213734_at), score: -0.89 RGPD5RANBP2-like and GRIP domain containing 5 (210676_x_at), score: 0.54 RGS2regulator of G-protein signaling 2, 24kDa (202388_at), score: 0.61 RGS3regulator of G-protein signaling 3 (203823_at), score: 0.36 RNF103ring finger protein 103 (202636_at), score: 0.37 RNF25ring finger protein 25 (218861_at), score: 0.34 RRADRas-related associated with diabetes (204802_at), score: 0.9 RUNX1runt-related transcription factor 1 (209360_s_at), score: 0.71 SC4MOLsterol-C4-methyl oxidase-like (209146_at), score: 0.46 SCARB1scavenger receptor class B, member 1 (201819_at), score: 0.42 SCDstearoyl-CoA desaturase (delta-9-desaturase) (200832_s_at), score: 0.32 SENP5SUMO1/sentrin specific peptidase 5 (213184_at), score: 0.34 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: 0.47 SERPINB8serpin peptidase inhibitor, clade B (ovalbumin), member 8 (206034_at), score: 0.37 SERPINF1serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (202283_at), score: 0.31 SETXsenataxin (201964_at), score: 0.38 SGK1serum/glucocorticoid regulated kinase 1 (201739_at), score: 0.35 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: 0.59 SIRPAsignal-regulatory protein alpha (202897_at), score: 0.35 SKILSKI-like oncogene (206675_s_at), score: 0.64 SLC10A3solute carrier family 10 (sodium/bile acid cotransporter family), member 3 (204928_s_at), score: 0.35 SLC19A2solute carrier family 19 (thiamine transporter), member 2 (209681_at), score: 0.8 SLC22A18solute carrier family 22, member 18 (204981_at), score: 0.35 SLC23A2solute carrier family 23 (nucleobase transporters), member 2 (209236_at), score: 0.32 SLC2A14solute carrier family 2 (facilitated glucose transporter), member 14 (222088_s_at), score: 0.39 SLC2A3P1solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 1 (221751_at), score: 0.35 SLC30A1solute carrier family 30 (zinc transporter), member 1 (212907_at), score: 0.33 SLC35F2solute carrier family 35, member F2 (218826_at), score: 0.31 SLC38A2solute carrier family 38, member 2 (220924_s_at), score: -0.86 SLC39A8solute carrier family 39 (zinc transporter), member 8 (209267_s_at), score: 0.41 SLC46A3solute carrier family 46, member 3 (214719_at), score: 0.38 SLC7A6solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (203578_s_at), score: 0.33 SMAD7SMAD family member 7 (204790_at), score: 0.44 SMOXspermine oxidase (210357_s_at), score: 0.83 SMURF1SMAD specific E3 ubiquitin protein ligase 1 (212666_at), score: 0.39 SOD2superoxide dismutase 2, mitochondrial (221477_s_at), score: 0.44 SOX4SRY (sex determining region Y)-box 4 (201417_at), score: 0.64 SOX9SRY (sex determining region Y)-box 9 (202935_s_at), score: 0.67 SPATA2Lspermatogenesis associated 2-like (214965_at), score: 0.54 SPHK1sphingosine kinase 1 (219257_s_at), score: 0.46 SPRED2sprouty-related, EVH1 domain containing 2 (212458_at), score: 0.74 SPRY2sprouty homolog 2 (Drosophila) (204011_at), score: 0.7 SPRY4sprouty homolog 4 (Drosophila) (221489_s_at), score: 0.69 SPSB1splA/ryanodine receptor domain and SOCS box containing 1 (219677_at), score: 0.64 SQLEsqualene epoxidase (213562_s_at), score: 0.66 SREBF2sterol regulatory element binding transcription factor 2 (201247_at), score: 0.49 SRFserum response factor (c-fos serum response element-binding transcription factor) (202401_s_at), score: 0.72 ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (208322_s_at), score: 0.7 STBD1starch binding domain 1 (203986_at), score: 0.5 STK38Lserine/threonine kinase 38 like (212572_at), score: 0.78 STMN1stathmin 1/oncoprotein 18 (200783_s_at), score: -0.85 SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (213247_at), score: 0.69 TBX3T-box 3 (219682_s_at), score: 0.5 TCTN1tectonic family member 1 (218584_at), score: 0.3 TEX2testis expressed 2 (218099_at), score: 0.3 TGFBR1transforming growth factor, beta receptor 1 (206943_at), score: 0.68 TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (201042_at), score: 0.35 THBDthrombomodulin (203887_s_at), score: 0.77 TICAM1toll-like receptor adaptor molecule 1 (213191_at), score: 0.47 TK1thymidine kinase 1, soluble (202338_at), score: -0.88 TM6SF1transmembrane 6 superfamily member 1 (219892_at), score: 0.58 TM7SF2transmembrane 7 superfamily member 2 (210130_s_at), score: 0.3 TMEM194Atransmembrane protein 194A (212621_at), score: -0.84 TMEM2transmembrane protein 2 (218113_at), score: 0.32 TMEM39Atransmembrane protein 39A (218615_s_at), score: 0.48 TMEM41Btransmembrane protein 41B (212623_at), score: 0.63 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (202510_s_at), score: 0.53 TNFAIP3tumor necrosis factor, alpha-induced protein 3 (202644_s_at), score: 0.53 TNFAIP6tumor necrosis factor, alpha-induced protein 6 (206026_s_at), score: 0.43 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (210260_s_at), score: 0.46 TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (207426_s_at), score: 0.59 TNS3tensin 3 (217853_at), score: 0.47 TNXAtenascin XA pseudogene (213451_x_at), score: 0.36 TNXBtenascin XB (216333_x_at), score: 0.41 TOB2transducer of ERBB2, 2 (221496_s_at), score: 0.32 TOM1target of myb1 (chicken) (202807_s_at), score: 0.45 TP53BP2tumor protein p53 binding protein, 2 (203120_at), score: 0.58 TP53I11tumor protein p53 inducible protein 11 (214667_s_at), score: 0.48 TPD52L1tumor protein D52-like 1 (203786_s_at), score: 0.35 TPP1tripeptidyl peptidase I (200742_s_at), score: 0.5 TPST1tyrosylprotein sulfotransferase 1 (204140_at), score: 0.42 TRAF3TNF receptor-associated factor 3 (221571_at), score: 0.39 TRAPPC10trafficking protein particle complex 10 (209412_at), score: 0.33 TRIB1tribbles homolog 1 (Drosophila) (202241_at), score: 0.82 TRIM22tripartite motif-containing 22 (213293_s_at), score: 0.39 TRIM32tripartite motif-containing 32 (203846_at), score: 0.31 TRIP13thyroid hormone receptor interactor 13 (204033_at), score: -0.85 TRMT5TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae) (221952_x_at), score: -0.92 TTC17tetratricopeptide repeat domain 17 (218972_at), score: 0.41 TWIST1twist homolog 1 (Drosophila) (213943_at), score: -0.9 UBA7ubiquitin-like modifier activating enzyme 7 (203281_s_at), score: 0.45 USTuronyl-2-sulfotransferase (205139_s_at), score: 0.33 UTP3UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) (209486_at), score: 0.35 VCLvinculin (200930_s_at), score: 0.49 VDRvitamin D (1,25- dihydroxyvitamin D3) receptor (204255_s_at), score: 0.5 VEGFAvascular endothelial growth factor A (211527_x_at), score: 0.89 VPS37Bvacuolar protein sorting 37 homolog B (S. cerevisiae) (221704_s_at), score: 0.42 WDR37WD repeat domain 37 (211383_s_at), score: 0.32 WEE1WEE1 homolog (S. pombe) (212533_at), score: -0.99 WISP1WNT1 inducible signaling pathway protein 1 (206796_at), score: 0.32 WTAPWilms tumor 1 associated protein (210285_x_at), score: 0.3 WWTR1WW domain containing transcription regulator 1 (202132_at), score: 0.4 XPO1exportin 1 (CRM1 homolog, yeast) (208775_at), score: -0.85 YRDCyrdC domain containing (E. coli) (218647_s_at), score: 0.67 ZNF263zinc finger protein 263 (203707_at), score: 0.3 ZNF282zinc finger protein 282 (212892_at), score: 0.43 ZNF35zinc finger protein 35 (206096_at), score: 0.7 ZNF672zinc finger protein 672 (218068_s_at), score: 0.57

Non-Entrez genes

Unknown, score:

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Id sample Experiment ExpName Array Syndrome Cell.line
1Twin.CEL 1 2 DS-twin hgu133plus2 Down DS-twin 1
5CTwin.CEL 5 2 DS-twin hgu133plus2 Down DS-twin 5
6Twin.CEL 6 2 DS-twin hgu133plus2 none DS-twin 6
2Twin.CEL 2 2 DS-twin hgu133plus2 none DS-twin 2
E-GEOD-3407-raw-cel-1437949557.cel 1 4 Cockayne hgu133a CS eGFP
46A.CEL 1 3 DS-mosaic hgu133plus2 none DS-mosaic 1
ctrl b 08-03.CEL 2 1 DS-CC hgu133a none DS-CC 2
ctrl a 08-03.CEL 1 1 DS-CC hgu133a none DS-CC 1
E-TABM-263-raw-cel-1515486351.cel 36 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486331.cel 35 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485851.cel 11 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486231.cel 30 6 Cycle hgu133a2 none Cycle 1

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