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DNA replication

The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.

chromosome segregation

The process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.

chromosome organization

A process that is carried out at the cellular level that results in the formation, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information.

mitotic sister chromatid segregation

The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.

cell cycle checkpoint

The cell cycle regulatory process by which progression through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage.

DNA replication checkpoint

A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.

DNA damage checkpoint

A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds.

G2 phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through G2 phase, one of two 'gap' phases in the mitotic cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of mitosis.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

microtubule cytoskeleton organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.

mitotic cell cycle

Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.

M phase

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the cell cycle comprising nuclear division.

nuclear division

A process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.

double-strand break repair via homologous recombination

The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.

recombinational repair

The repair of damaged DNA that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA.

DNA synthesis during DNA repair

Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template.

sister chromatid segregation

The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets.

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

regulation of cell cycle

Any process that modulates the rate or extent of progression through the cell cycle.

cytoskeleton organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

DNA metabolic process

The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

DNA-dependent DNA replication

The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.

DNA unwinding during replication

The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.

DNA replication initiation

The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.

regulation of DNA replication

Any process that modulates the frequency, rate or extent of DNA replication.

DNA repair

The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

nucleotide-excision repair

In nucleotide excision repair a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).

nucleotide-excision repair, DNA gap filling

Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes.

double-strand break repair

The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.

DNA recombination

Any process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.

DNA packaging

Any process by which DNA and associated proteins are formed into a compact, orderly structure.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

response to DNA damage stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

organelle organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

microtubule-based process

Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

spindle organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

mitotic chromosome condensation

The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells.

mitotic cell cycle checkpoint

A signal transduction-based surveillance mechanism that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

intracellular signaling cascade

A series of reactions within the cell that occur as a result of a single trigger reaction or compound.

regulation of mitotic cell cycle

Any process that modulates the rate or extent of progress through the mitotic cell cycle.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

negative regulation of DNA replication

Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication.

biosynthetic process

The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.

negative regulation of biosynthetic process

Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.

negative regulation of metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of macromolecule biosynthetic process

Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

negative regulation of macromolecule biosynthetic process

Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of cell cycle process

Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

negative regulation of macromolecule metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

cellular component organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component.

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

cell cycle phase

A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events.

regulation of DNA replication initiation

Any process that modulates the frequency, rate or extent of initiation of DNA replication; the process by which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.

chromosome condensation

The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

negative regulation of cellular metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

regulation of cellular biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

negative regulation of cellular biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

DNA integrity checkpoint

Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure.

negative regulation of DNA replication initiation

Any process that stops, prevents or reduces the frequency, rate or extent of initiation of DNA replication.

DNA geometric change

The process by which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.

DNA duplex unwinding

The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.

cellular response to stress

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

cellular response to DNA damage stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

DNA damage response, signal transduction

A cascade of processes induced by the detection of DNA damage within a cell.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.

biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

organelle fission

The creation of two or more organelles by division of one organelle.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of cellular process

Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of DNA metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.

negative regulation of DNA metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.

cell division

The process resulting in the physical partitioning and separation of a cell into daughter cells.

G2 phase

A cell cycle process comprising the steps by which a cell progresses through G2 phase, one of two 'gap' phases in the cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).

S phase

A cell cycle process comprising the steps by which a cell progresses through S phase, the part of the cell cycle during which DNA synthesis takes place.

interphase

A cell cycle process comprising the steps by which a cell progresses through interphase, the stage of cell cycle between successive rounds of chromosome segregation. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs.

interphase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs.

cellular response to stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of macromolecule metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

negative regulation of metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

negative regulation of cellular process

Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cellular response to stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biosynthetic process

Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.

regulation of biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.

negative regulation of metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

negative regulation of macromolecule metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of macromolecule metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

negative regulation of cellular metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

sister chromatid segregation

The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets.

negative regulation of cellular metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

regulation of cell cycle

Any process that modulates the rate or extent of progression through the cell cycle.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

negative regulation of cellular process

Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cellular response to stress

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

negative regulation of biosynthetic process

Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.

regulation of macromolecule biosynthetic process

Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

negative regulation of macromolecule biosynthetic process

Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of cellular biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

negative regulation of cellular biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

negative regulation of macromolecule biosynthetic process

Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

negative regulation of cellular biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

negative regulation of cellular metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

regulation of cellular biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

regulation of macromolecule biosynthetic process

Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

negative regulation of macromolecule metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of mitotic cell cycle

Any process that modulates the rate or extent of progress through the mitotic cell cycle.

regulation of cell cycle process

Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

cellular response to DNA damage stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

negative regulation of macromolecule biosynthetic process

Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

regulation of DNA replication

Any process that modulates the frequency, rate or extent of DNA replication.

negative regulation of cellular biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

negative regulation of DNA replication

Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication.

negative regulation of DNA replication

Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication.

negative regulation of DNA metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.

negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of DNA metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.

regulation of DNA replication

Any process that modulates the frequency, rate or extent of DNA replication.

negative regulation of DNA metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.

DNA metabolic process

The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

regulation of DNA metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.

negative regulation of DNA metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.

mitotic chromosome condensation

The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

mitotic cell cycle checkpoint

A signal transduction-based surveillance mechanism that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.

mitotic chromosome condensation

The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells.

sister chromatid segregation

The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets.

chromosome condensation

The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.

microtubule cytoskeleton organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

spindle organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.

mitotic sister chromatid segregation

The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.

G2 phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through G2 phase, one of two 'gap' phases in the mitotic cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of mitosis.

G2 phase

A cell cycle process comprising the steps by which a cell progresses through G2 phase, one of two 'gap' phases in the cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).

S phase

A cell cycle process comprising the steps by which a cell progresses through S phase, the part of the cell cycle during which DNA synthesis takes place.

interphase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs.

DNA repair

The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

DNA damage response, signal transduction

A cascade of processes induced by the detection of DNA damage within a cell.

negative regulation of DNA replication

Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication.

DNA replication

The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.

regulation of DNA replication

Any process that modulates the frequency, rate or extent of DNA replication.

negative regulation of DNA replication

Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication.

regulation of DNA replication initiation

Any process that modulates the frequency, rate or extent of initiation of DNA replication; the process by which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.

negative regulation of DNA replication initiation

Any process that stops, prevents or reduces the frequency, rate or extent of initiation of DNA replication.

DNA synthesis during DNA repair

Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template.

recombinational repair

The repair of damaged DNA that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA.

DNA damage checkpoint

A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

negative regulation of DNA replication initiation

Any process that stops, prevents or reduces the frequency, rate or extent of initiation of DNA replication.

DNA replication checkpoint

A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.

DNA replication initiation

The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.

nucleotide-excision repair, DNA gap filling

Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes.

double-strand break repair via homologous recombination

The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.

DNA unwinding during replication

The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.

nuclear chromosome

A chromosome found in the nucleus of a eukaryotic cell.

condensed nuclear chromosome

A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure that remains in the nucleus.

condensed chromosome

A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

chromosome, centromeric region

The region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

condensed chromosome kinetochore

A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.

condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

condensin complex

A multisubunit protein complex that plays a central role in chromosome condensation.

outer kinetochore of condensed chromosome

The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

collagen

Any of the various assemblies in which collagen chains form a left-handed triple helix; may assemble into higher order structures.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

proteinaceous extracellular matrix

A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

replication fork

The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.

alpha DNA polymerase:primase complex

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

chromosome

A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

cytoskeleton

Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

microtubule cytoskeleton

The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.

replisome

A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

sheet-forming collagen

Any collagen polymer in which collagen triple helices associate to form sheet-like networks.

extracellular matrix

A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants).

membrane-enclosed lumen

The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.

nuclear lumen

The volume enclosed by the nuclear inner membrane.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

protein-DNA complex

A macromolecular complex containing both protein and DNA molecules.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

organelle lumen

The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

nuclear replication fork

The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.

nuclear replisome

A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

extracellular matrix part

Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

chromosomal part

Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

nuclear part

Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

nuclear chromosome part

Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

intracellular organelle lumen

An organelle lumen that is part of an intracellular organelle.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

organelle lumen

The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

extracellular matrix part

Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).

intracellular organelle lumen

An organelle lumen that is part of an intracellular organelle.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

collagen

Any of the various assemblies in which collagen chains form a left-handed triple helix; may assemble into higher order structures.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

condensin complex

A multisubunit protein complex that plays a central role in chromosome condensation.

outer kinetochore of condensed chromosome

The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.

replisome

A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

nuclear lumen

The volume enclosed by the nuclear inner membrane.

nuclear chromosome part

Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

alpha DNA polymerase:primase complex

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

outer kinetochore of condensed chromosome

The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.

nuclear part

Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.

nuclear chromosome

A chromosome found in the nucleus of a eukaryotic cell.

chromosomal part

Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

replisome

A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

alpha DNA polymerase:primase complex

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

nuclear replication fork

The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.

nuclear replisome

A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

nuclear chromosome part

Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.

condensed nuclear chromosome

A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure that remains in the nucleus.

condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

condensin complex

A multisubunit protein complex that plays a central role in chromosome condensation.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

condensed chromosome kinetochore

A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.

nuclear replisome

A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

ATPase activity, coupled

Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane.

motor activity

Catalysis of movement along a polymeric molecule such as a microfilament or microtubule, coupled to the hydrolysis of a nucleoside triphosphate.

microtubule motor activity

Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

nucleoside-triphosphatase activity

Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.

DNA-dependent ATPase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single- or double-stranded DNA; drives another reaction.

ATPase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate. May or may not be coupled to another reaction.

pyrophosphatase activity

Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

hydrolase activity, acting on acid anhydrides

Catalysis of the hydrolysis of any acid anhydride.

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.

all

This term is the most general term possible

Id	Pvalue	ExpCount	Count	Size	Term
GO:0022403	7.621e-27	18.93	79 ASPM, AURKA, AURKB, BIRC5, BLM, BRCA2, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCNE1, CCNF, CDC20, CDC25A, CDC6, CDC7, CDCA3, CDCA8, CDK2, CDKN2D, CDT1, CENPE, CENPF, CHEK1, CIT, DDX11, DMC1, DSN1, E2F1, ERCC6L, ESPL1, EXO1, FAM29A, FOXN3, GTSE1, HELLS, IL1A, KIF11, KIF15, KIF20B, KIF22, KIF23, KIF2C, KIFC1, KNTC1, MAD2L1, MRE11A, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, PKIA, PKMYT1, POLA1, POLD1, POLE, PSMC3IP, RAD51, RAD54B, RAD54L, SMC2, SMC4, SPAG5, SPC25, STMN1, TACC3, TCF7L1, TIMELESS, TIPIN, TPD52L1, TPX2, TTK, UBE2C, ZWILCH, ZWINT	285	cell cycle phase
GO:0000279	6.428e-23	15.28	66 ASPM, AURKA, AURKB, BIRC5, BRCA2, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCNF, CDC20, CDC25A, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, CHEK1, CIT, DDX11, DMC1, DSN1, ERCC6L, ESPL1, EXO1, FAM29A, HELLS, IL1A, KIF11, KIF15, KIF20B, KIF22, KIF23, KIF2C, KIFC1, KNTC1, MAD2L1, MRE11A, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, PKMYT1, PSMC3IP, RAD51, RAD54B, RAD54L, SMC2, SMC4, SPAG5, SPC25, STMN1, TACC3, TCF7L1, TIMELESS, TIPIN, TPX2, TTK, UBE2C, ZWILCH, ZWINT	230	M phase
GO:0007049	2.758e-22	42.91	116 ASNS, ASPM, AURKA, AURKB, BARD1, BIRC5, BLM, BRCA1, BRCA2, BRIP1, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCND3, CCNE1, CCNE2, CCNF, CDC20, CDC25A, CDC45L, CDC6, CDC7, CDCA3, CDCA8, CDK2, CDKN2D, CDT1, CENPE, CENPF, CHAF1A, CHAF1B, CHEK1, CIT, CKAP2, DDX11, DDX12, DIRAS3, DMC1, DSCC1, DSN1, E2F1, E2F8, ERCC6L, ESPL1, EXO1, FAM29A, FANCG, FANCI, FOXN3, GMNN, GTSE1, HELLS, IL1A, KIF11, KIF15, KIF20B, KIF22, KIF23, KIF2C, KIFC1, KNTC1, KRT18, LIG1, MAD2L1, MAP3K8, MCM2, MCM3, MCM6, MCM7, MKI67, MRE11A, MSH2, NBL1, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, PDCD4, PKIA, PKMYT1, PLA2G16, POLA1, POLD1, POLE, PSMB9, PSMC3IP, PSMD2, PSRC1, RACGAP1, RAD51, RAD54B, RAD54L, RAD9A, RBL1, SMC2, SMC4, SPAG5, SPC25, STMN1, SUV39H1, TACC3, TCF7L1, TIMELESS, TIPIN, TP53, TPD52L1, TPX2, TTK, UBE2C, ZWILCH, ZWINT	646	cell cycle
GO:0022402	1.184e-21	26.04	86 ASPM, AURKA, AURKB, BARD1, BIRC5, BLM, BRCA1, BRCA2, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCNE1, CCNF, CDC20, CDC25A, CDC6, CDC7, CDCA3, CDCA8, CDK2, CDKN2D, CDT1, CENPE, CENPF, CHEK1, CIT, DDX11, DMC1, DSN1, E2F1, ERCC6L, ESPL1, EXO1, FAM29A, FOXN3, GTSE1, HELLS, IL1A, KIF11, KIF15, KIF20B, KIF22, KIF23, KIF2C, KIFC1, KNTC1, MAD2L1, MRE11A, MSH2, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, PKIA, PKMYT1, POLA1, POLD1, POLE, PSMB9, PSMC3IP, PSMD2, RACGAP1, RAD51, RAD54B, RAD54L, SMC2, SMC4, SPAG5, SPC25, STMN1, TACC3, TCF7L1, TIMELESS, TIPIN, TP53, TPD52L1, TPX2, TTK, UBE2C, ZWILCH, ZWINT	392	cell cycle process
GO:0006260	5.235e-21	11.96	56 BLM, BRCA1, BRCA2, CDC25A, CDC45L, CDC6, CDC7, CDK2, CDKN2D, CDT1, CHAF1A, CHAF1B, CHEK1, DNA2, DSCC1, DTL, EXO1, FEN1, GINS1, GINS2, GINS3, GINS4, GMNN, HMGA1, LIG1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MRE11A, MSH2, ORC1L, ORC6L, PDGFA, POLA1, POLA2, POLD1, POLD3, POLE, POLE2, POLQ, PRIM1, RAD51, RAD9A, RFC2, RFC3, RFC4, RMI1, RNASEH2A, SUPT16H, TDG, TIPIN, TP53	180	DNA replication
GO:0000278	5.276e-21	20.79	75 ASNS, ASPM, AURKA, AURKB, BIRC5, BLM, BRCA2, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCNE1, CCNF, CDC20, CDC25A, CDC6, CDC7, CDCA3, CDCA8, CDK2, CDKN2D, CDT1, CENPE, CENPF, CHEK1, CIT, DDX11, DSN1, E2F1, ERCC6L, ESPL1, FAM29A, FOXN3, GTSE1, HELLS, IL1A, KIF11, KIF15, KIF20B, KIF22, KIF23, KIF2C, KIFC1, KNTC1, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, PKIA, PKMYT1, POLA1, POLD1, POLE, PSMB9, PSMD2, SMC2, SMC4, SPAG5, SPC25, STMN1, TCF7L1, TIMELESS, TIPIN, TP53, TPD52L1, TPX2, TTK, UBE2C, ZWILCH, ZWINT	313	mitotic cell cycle
GO:0000280	2.946e-20	11.49	54 ASPM, AURKA, AURKB, BIRC5, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCNF, CDC20, CDC25A, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, CIT, DDX11, DSN1, ERCC6L, ESPL1, FAM29A, HELLS, IL1A, KIF11, KIF15, KIF20B, KIF22, KIF23, KIF2C, KIFC1, KNTC1, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, PKMYT1, SMC2, SMC4, SPAG5, SPC25, TCF7L1, TIMELESS, TIPIN, TPX2, UBE2C, ZWILCH, ZWINT	173	nuclear division
GO:0007067	2.946e-20	11.49	54 ASPM, AURKA, AURKB, BIRC5, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCNF, CDC20, CDC25A, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, CIT, DDX11, DSN1, ERCC6L, ESPL1, FAM29A, HELLS, IL1A, KIF11, KIF15, KIF20B, KIF22, KIF23, KIF2C, KIFC1, KNTC1, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, PKMYT1, SMC2, SMC4, SPAG5, SPC25, TCF7L1, TIMELESS, TIPIN, TPX2, UBE2C, ZWILCH, ZWINT	173	mitosis
GO:0000087	7.377e-20	11.69	54 ASPM, AURKA, AURKB, BIRC5, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCNF, CDC20, CDC25A, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, CIT, DDX11, DSN1, ERCC6L, ESPL1, FAM29A, HELLS, IL1A, KIF11, KIF15, KIF20B, KIF22, KIF23, KIF2C, KIFC1, KNTC1, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, PKMYT1, SMC2, SMC4, SPAG5, SPC25, TCF7L1, TIMELESS, TIPIN, TPX2, UBE2C, ZWILCH, ZWINT	176	M phase of mitotic cell cycle
GO:0048285	1.793e-19	11.89	54 ASPM, AURKA, AURKB, BIRC5, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCNF, CDC20, CDC25A, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, CIT, DDX11, DSN1, ERCC6L, ESPL1, FAM29A, HELLS, IL1A, KIF11, KIF15, KIF20B, KIF22, KIF23, KIF2C, KIFC1, KNTC1, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, PKMYT1, SMC2, SMC4, SPAG5, SPC25, TCF7L1, TIMELESS, TIPIN, TPX2, UBE2C, ZWILCH, ZWINT	179	organelle fission
GO:0051301	2.302e-16	12.75	52 ASPM, AURKB, BLM, BRCA2, BUB1, BUB1B, C18orf24, C21orf45, CCNA2, CCND3, CCNE1, CCNE2, CCNF, CDC20, CDC25A, CDC6, CDC7, CDCA3, CDCA8, CDK2, CENPE, CENPF, CIT, DSN1, ERCC6L, ESPL1, FAM29A, HELLS, KIF11, KIF20B, KIF23, KIFC1, KNTC1, LIG1, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, RACGAP1, SMC2, SMC4, SPAG5, SPC25, TIMELESS, TIPIN, UBE2C, ZWILCH, ZWINT	192	cell division
GO:0006259	5.546e-14	24.64	71 BLM, BRCA1, BRCA2, BRIP1, CDC25A, CDC45L, CDC6, CDC7, CDK2, CDKN2D, CDT1, CHAF1A, CHAF1B, CHEK1, DCLRE1B, DCLRE1C, DMC1, DNA2, DSCC1, DTL, EXO1, FANCA, FANCG, FANCI, FEN1, GINS1, GINS2, GINS3, GINS4, GMNN, HELLS, HMGA1, LIG1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MRE11A, MSH2, ORC1L, ORC6L, PARP2, PDGFA, POLA1, POLA2, POLD1, POLD3, POLE, POLE2, POLQ, PRIM1, PSMC3IP, RAD51, RAD51AP1, RAD54B, RAD54L, RAD9A, RFC2, RFC3, RFC4, RMI1, RNASEH2A, SUPT16H, TDG, TIPIN, TOPBP1, TP53, UNG	371	DNA metabolic process
GO:0000075	3.050e-11	3.521	23 BLM, BRIP1, BUB1, BUB1B, CCNA2, CCNE2, CDC45L, CDC6, CDT1, CENPF, CHEK1, FANCG, FOXN3, GTSE1, KNTC1, MAD2L1, MSH2, RAD9A, TIPIN, TP53, TTK, ZWILCH, ZWINT	53	cell cycle checkpoint
GO:0006261	9.301e-10	4.052	23 CDC45L, CDC6, CDT1, EXO1, HMGA1, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MSH2, ORC1L, POLA1, POLD3, POLE2, PRIM1, RAD51, RAD9A, RFC3, RFC4, TDG, TIPIN	61	DNA-dependent DNA replication
GO:0006270	9.846e-09	1.329	13 CDC45L, CDC6, CDT1, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, ORC1L, POLA1, RAD9A, TIPIN	20	DNA replication initiation
GO:0051726	4.169e-08	17.07	47 ASNS, BLM, BRCA1, BRCA2, BRIP1, BUB1, BUB1B, CCNA2, CCND3, CCNE2, CDC25A, CDC45L, CDC6, CDC7, CDK2, CDKN2D, CDT1, CENPF, CHEK1, DIRAS3, E2F1, ESPL1, FANCG, FOXN3, GMNN, GTSE1, IL1A, KIF20B, KNTC1, MAD2L1, MSH2, NBL1, NEK2, PDCD4, PKIA, PKMYT1, PLA2G16, RAD9A, RBL1, TACC3, TIMELESS, TIPIN, TP53, TTK, UBE2C, ZWILCH, ZWINT	257	regulation of cell cycle
GO:0006974	7.895e-08	17.4	47 BARD1, BLM, BRCA1, BRCA2, BRIP1, CCNA2, CDKN2D, CHAF1A, CHAF1B, CHEK1, DCLRE1B, DCLRE1C, DTL, EXO1, FANCA, FANCG, FANCI, FEN1, FOXN3, GTSE1, LIG1, MCM7, MRE11A, MSH2, NUPR1, PARP2, POLA1, POLD1, POLD3, POLE, POLE2, POLQ, RAD51, RAD51AP1, RAD54B, RAD54L, RAD9A, RFC2, RFC3, RFC4, SUPT16H, TDG, TIMELESS, TIPIN, TOPBP1, TP53, UNG	262	response to DNA damage stimulus
GO:0034984	1.828e-07	15.48	43 BLM, BRCA1, BRCA2, BRIP1, CCNA2, CDKN2D, CHAF1A, CHAF1B, CHEK1, DCLRE1B, DCLRE1C, EXO1, FANCA, FANCG, FANCI, FEN1, FOXN3, GTSE1, LIG1, MRE11A, MSH2, NUPR1, PARP2, POLA1, POLD1, POLD3, POLE, POLE2, POLQ, RAD51, RAD51AP1, RAD54B, RAD54L, RAD9A, RFC2, RFC3, RFC4, SUPT16H, TDG, TIPIN, TOPBP1, TP53, UNG	233	cellular response to DNA damage stimulus
GO:0007346	3.737e-07	5.779	24 ASNS, BLM, BRCA2, BUB1, BUB1B, CCNA2, CDC6, CDK2, CDT1, CENPF, ESPL1, GTSE1, IL1A, KIF20B, KNTC1, MAD2L1, NEK2, PKIA, PKMYT1, TP53, TTK, UBE2C, ZWILCH, ZWINT	87	regulation of mitotic cell cycle
GO:0006281	1.130e-06	13.48	38 BLM, BRCA1, BRCA2, BRIP1, CDKN2D, CHAF1A, CHAF1B, CHEK1, DCLRE1B, DCLRE1C, EXO1, FANCA, FANCG, FANCI, FEN1, LIG1, MRE11A, MSH2, PARP2, POLA1, POLD1, POLD3, POLE, POLE2, POLQ, RAD51, RAD51AP1, RAD54B, RAD54L, RAD9A, RFC2, RFC3, RFC4, SUPT16H, TDG, TOPBP1, TP53, UNG	203	DNA repair
GO:0031570	1.159e-06	1.793	13 BLM, BRIP1, CCNA2, CDC45L, CDC6, CDT1, CHEK1, FOXN3, GTSE1, MSH2, RAD9A, TIPIN, TP53	27	DNA integrity checkpoint
GO:0051325	1.626e-06	4.849	21 BLM, BRCA2, CCNE1, CDC6, CDC7, CDK2, CDKN2D, CDT1, CENPF, CHEK1, DDX11, E2F1, FOXN3, GTSE1, PKIA, POLA1, POLD1, POLE, TIMELESS, TIPIN, TPD52L1	73	interphase
GO:0000070	1.670e-05	1.528	11 CENPE, DDX11, ESPL1, KIFC1, NCAPD3, NCAPG, NCAPG2, NCAPH, SMC2, SMC4, ZWINT	23	mitotic sister chromatid segregation
GO:0051329	1.990e-05	4.65	19 BLM, BRCA2, CCNE1, CDC6, CDC7, CDK2, CDKN2D, CDT1, CENPF, CHEK1, DDX11, E2F1, FOXN3, GTSE1, PKIA, POLA1, POLD1, POLE, TPD52L1	70	interphase of mitotic cell cycle
GO:0006996	2.003e-05	59.38	99 ASF1B, ASPM, AURKA, AURKB, BIRC5, BLM, BRCA1, BRCA2, BUB1, BUB1B, C18orf24, C21orf45, CAPG, CCNA2, CCNF, CDC20, CDC25A, CDC6, CDCA3, CDCA8, CDK2, CENPE, CENPF, CHAF1A, CHAF1B, CIT, CPA4, DAAM1, DAAM2, DDX11, DSN1, ERCC6L, ESPL1, EXOSC9, EZH2, FAM29A, FANCG, FHOD3, GOLGB1, GSN, HELLS, HIP1, HMGA1, HTRA2, IL1A, KIF11, KIF15, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, KNTC1, LIMK1, MAD2L1, MCM2, MRE11A, MSH2, NAP1L4, NCAPD3, NCAPG, NCAPG2, NCAPH, NEDD9, NEK2, OIP5, OPTN, PDGFA, PKMYT1, PLEK2, PMAIP1, PRKG1, PSRC1, RACGAP1, RAD54L, RBL1, S1PR1, SLC25A4, SMC2, SMC4, SPAG5, SPC25, STMN1, SUPT16H, SUV39H1, SUZ12, TACC3, TCF7L1, TIMELESS, TIPIN, TP53, TPX2, TTK, TUBGCP5, UBE2C, WHSC1, ZWILCH, ZWINT	894	organelle organization
GO:0000819	2.758e-05	1.594	11 CENPE, DDX11, ESPL1, KIFC1, NCAPD3, NCAPG, NCAPG2, NCAPH, SMC2, SMC4, ZWINT	24	sister chromatid segregation
GO:0007093	2.883e-05	1.926	12 BLM, BUB1, BUB1B, CCNA2, CENPF, GTSE1, KNTC1, MAD2L1, TP53, TTK, ZWILCH, ZWINT	29	mitotic cell cycle checkpoint
GO:0007051	4.408e-05	1.661	11 AURKA, BUB1B, ESPL1, KIF11, KIF23, SPAG5, STMN1, TACC3, TTK, UBE2C, ZWINT	25	spindle organization
GO:0006302	5.362e-05	2.391	13 BLM, BRCA1, BRCA2, BRIP1, FEN1, MRE11A, MSH2, POLA1, RAD51, RAD51AP1, RAD54B, RAD54L, TP53	36	double-strand break repair
GO:0007017	1.139e-04	8.901	26 AURKA, BRCA1, BRCA2, BUB1B, CENPE, ESPL1, GTSE1, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, NEK2, PSRC1, SPAG5, STMN1, TACC3, TTK, TUBGCP5, UBE2C, ZWINT	134	microtubule-based process
GO:0007059	1.795e-04	3.056	14 BRCA1, CENPE, CENPF, DDX11, DSN1, ESPL1, KIFC1, NCAPD3, NCAPG, NCAPG2, NCAPH, SMC2, SMC4, ZWINT	46	chromosome segregation
GO:0033554	1.917e-04	21.26	45 ASNS, BLM, BRCA1, BRCA2, BRIP1, CCNA2, CDKN2D, CHAF1A, CHAF1B, CHEK1, DCLRE1B, DCLRE1C, EXO1, FANCA, FANCG, FANCI, FEN1, FOXN3, GTSE1, LIG1, MRE11A, MSH2, NEDD4, NUPR1, PARP2, POLA1, POLD1, POLD3, POLE, POLE2, POLQ, RAD51, RAD51AP1, RAD54B, RAD54L, RAD9A, RFC2, RFC3, RFC4, SUPT16H, TDG, TIPIN, TOPBP1, TP53, UNG	320	cellular response to stress
GO:0000077	2.461e-04	1.594	10 BLM, BRIP1, CCNA2, CHEK1, FOXN3, GTSE1, MSH2, RAD9A, TIPIN, TP53	24	DNA damage checkpoint
GO:0051320	2.872e-04	0.9964	8 BRCA2, CDC7, CDT1, DDX11, POLA1, POLD1, TIMELESS, TIPIN	15	S phase
GO:0051716	3.183e-04	22.39	46 ASNS, BLM, BRCA1, BRCA2, BRIP1, CCNA2, CDKN2D, CHAF1A, CHAF1B, CHEK1, DCLRE1B, DCLRE1C, ENPP1, EXO1, FANCA, FANCG, FANCI, FEN1, FOXN3, GTSE1, LIG1, MRE11A, MSH2, NEDD4, NUPR1, PARP2, POLA1, POLD1, POLD3, POLE, POLE2, POLQ, RAD51, RAD51AP1, RAD54B, RAD54L, RAD9A, RFC2, RFC3, RFC4, SUPT16H, TDG, TIPIN, TOPBP1, TP53, UNG	337	cellular response to stimulus
GO:0000731	3.783e-04	0.5314	6 CDKN2D, POLA1, POLD1, POLD3, POLE, RFC3	8	DNA synthesis during DNA repair
GO:0010564	6.056e-04	3.388	14 BRCA1, BRCA2, CDC7, CDT1, ESPL1, IL1A, KIF20B, KNTC1, NEK2, PKIA, PKMYT1, TIMELESS, TIPIN, UBE2C	51	regulation of cell cycle process
GO:0042770	7.076e-04	2.989	13 BLM, BRCA1, BRCA2, BRIP1, CCNA2, CHEK1, FOXN3, GTSE1, MSH2, NUPR1, RAD9A, TIPIN, TP53	45	DNA damage response, signal transduction
GO:0006297	8.300e-04	1.129	8 LIG1, POLD1, POLD3, POLE, POLE2, RFC2, RFC3, RFC4	17	nucleotide-excision repair, DNA gap filling
GO:0008156	8.623e-04	1.461	9 BLM, BRCA2, CDC45L, CDC6, CDT1, GMNN, RAD9A, TIPIN, TP53	22	negative regulation of DNA replication
GO:0000076	1.113e-03	0.3986	5 CDC45L, CDC6, CDT1, RAD9A, TIPIN	6	DNA replication checkpoint
GO:0032297	1.113e-03	0.3986	5 CDC45L, CDC6, CDT1, RAD9A, TIPIN	6	negative regulation of DNA replication initiation
GO:0000226	1.284e-03	5.115	17 AURKA, BRCA1, BRCA2, BUB1B, ESPL1, KIF11, KIF23, KIF2C, NEK2, PSRC1, SPAG5, STMN1, TACC3, TTK, TUBGCP5, UBE2C, ZWINT	77	microtubule cytoskeleton organization
GO:0051053	1.438e-03	1.926	10 BLM, BRCA2, CDC45L, CDC6, CDT1, GMNN, MSH2, RAD9A, TIPIN, TP53	29	negative regulation of DNA metabolic process
GO:0000724	1.792e-03	0.93	7 BLM, BRCA1, BRCA2, RAD51, RAD51AP1, RAD54B, RAD54L	14	double-strand break repair via homologous recombination
GO:0000725	1.792e-03	0.93	7 BLM, BRCA1, BRCA2, RAD51, RAD51AP1, RAD54B, RAD54L	14	recombinational repair
GO:0051052	2.638e-03	4.384	15 BLM, BRCA1, BRCA2, CDC45L, CDC6, CDK2, CDT1, GMNN, MRE11A, MSH2, PDGFA, RAD51, RAD9A, TIPIN, TP53	66	regulation of DNA metabolic process
GO:0030174	3.070e-03	0.465	5 CDC45L, CDC6, CDT1, RAD9A, TIPIN	7	regulation of DNA replication initiation
GO:0006268	3.597e-03	0.7307	6 HMGA1, MCM2, MCM4, MCM6, MCM7, RAD51	11	DNA unwinding during replication
GO:0006275	4.655e-03	2.657	11 BLM, BRCA2, CDC45L, CDC6, CDK2, CDT1, GMNN, PDGFA, RAD9A, TIPIN, TP53	40	regulation of DNA replication
GO:0007076	6.034e-03	0.7971	6 NCAPD3, NCAPG, NCAPG2, NCAPH, SMC2, SMC4	12	mitotic chromosome condensation
GO:0006310	7.117e-03	5.38	16 BLM, BRCA1, BRCA2, CHEK1, DCLRE1C, DMC1, EXO1, HMGA1, LIG1, MRE11A, MSH2, PSMC3IP, RAD51, RAD51AP1, RAD54B, RAD54L	81	DNA recombination
GO:0000085	9.107e-03	0.3321	4 BLM, CENPF, FOXN3, GTSE1	5	G2 phase of mitotic cell cycle
GO:0051319	9.107e-03	0.3321	4 BLM, CENPF, FOXN3, GTSE1	5	G2 phase
GO:0009314	1.267e-02	5.713	16 ATXN1, BLM, BRCA2, CDKN2D, FANCG, FEN1, KIT, MSH2, NEDD4, OPN3, POLD1, RAD54B, RAD54L, SCARA3, TOPBP1, TP53	86	response to radiation
GO:0032392	1.378e-02	0.93	6 HMGA1, MCM2, MCM4, MCM6, MCM7, RAD51	14	DNA geometric change
GO:0032508	1.378e-02	0.93	6 HMGA1, MCM2, MCM4, MCM6, MCM7, RAD51	14	DNA duplex unwinding
GO:0007126	1.863e-02	3.188	11 BRCA2, CHEK1, DMC1, ESPL1, EXO1, MRE11A, NEK2, PSMC3IP, RAD51, RAD54B, RAD54L	48	meiosis
GO:0051321	1.863e-02	3.188	11 BRCA2, CHEK1, DMC1, ESPL1, EXO1, MRE11A, NEK2, PSMC3IP, RAD51, RAD54B, RAD54L	48	meiotic cell cycle
GO:0051327	1.863e-02	3.188	11 BRCA2, CHEK1, DMC1, ESPL1, EXO1, MRE11A, NEK2, PSMC3IP, RAD51, RAD54B, RAD54L	48	M phase of meiotic cell cycle
GO:0033261	1.898e-02	0.6643	5 BRCA2, CDC7, CDT1, TIMELESS, TIPIN	10	regulation of S phase
GO:0030261	1.939e-02	0.9964	6 NCAPD3, NCAPG, NCAPG2, NCAPH, SMC2, SMC4	15	chromosome condensation
GO:0019932	2.114e-02	6.045	16 AGTR1, AURKA, BUB1B, CCL2, CDH13, FEN1, HTR1F, NPR3, PTGER4, RAPGEF2, RCAN3, RFC4, S1PR1, SPAG5, UBE2C, ZWINT	91	second-messenger-mediated signaling
GO:0006271	2.176e-02	0.1993	3 POLA1, RFC3, RFC4	3	DNA strand elongation during DNA replication
GO:0048478	2.176e-02	0.1993	3 BLM, BRCA2, TIPIN	3	replication fork protection
GO:0048856	2.784e-02	80.18	108 ACAN, AGTR1, ALDH1A3, ANPEP, BAIAP2, BLM, BRCA2, CA9, CAPG, CCL2, CCNF, CDH13, CDH4, CDKN2D, CENPF, CHPT1, CIT, CLEC3B, COL4A2, COL8A1, COMP, CORIN, DFNA5, DHCR7, DMC1, DMD, DPYSL2, E2F1, EMX2, ENPP1, F2R, FANCG, FHL1, FOXE1, FOXF2, FST, GATA2, GATA6, GINS1, GPC4, GSTM3, HELLS, HMGB3, HOXB7, HOXC10, HOXC11, HTRA2, ID1, IER3, IFT20, IL1A, IL6, ITGA2, ITGA8, JAG1, KIT, KRT18, LAMA2, LAMC2, LIG1, LIMK1, LRP5, MBP, MEOX2, MEST, MGP, MMP14, MMP2, MSH2, NEDD4, NET1, NOV, NPR3, NRG1, NRXN3, NUPR1, OLFM1, PALM, PITX2, POSTN, PPL, PRELP, PRKG1, PRRX2, PSRC1, PTGER4, PTPRZ1, RCAN3, RELN, RORA, S1PR1, SCRG1, SECTM1, SFRP1, SIX2, SLIT2, SPOCK1, SRGN, STMN1, TACC3, TCF7L1, TFAP2A, TLR4, TNS3, TP53, TUFT1, WHSC1, ZNF423	1207	anatomical structure development
GO:0032502	3.065e-02	124.2	156 ACAN, AGTR1, ALDH1A3, ANPEP, ASF1B, ASNS, ATXN1, BAIAP2, BARD1, BIRC5, BLM, BRCA1, BRCA2, BST1, BUB1B, CA9, CAPG, CASP2, CCL2, CCNF, CDH13, CDH4, CDKN2D, CENPF, CENPI, CHPT1, CIT, CKAP2, CLEC3B, COL13A1, COL4A2, COL8A1, COMP, CORIN, CYFIP2, DACT1, DFNA5, DHCR7, DMC1, DMD, DPYSL2, DRAM, E2F1, EDIL3, EMX2, ENPP1, ESPL1, F2R, FANCG, FHL1, FOXE1, FOXF2, FST, FZD7, GATA2, GATA6, GINS1, GNPTAB, GPC4, GSTM3, HELLS, HIP1, HMGB3, HOXA9, HOXB7, HOXC10, HOXC11, HTRA2, ID1, IER3, IFI27, IFT20, IL1A, IL6, ITGA2, ITGA8, JAG1, KIT, KLF9, KRT18, LAMA2, LAMA5, LAMC2, LIG1, LIMK1, LMO2, LRP5, MBP, MEOX2, MEST, MGP, MMD, MMP14, MMP2, MSH2, NEDD4, NET1, NKX3-1, NOV, NPR3, NRG1, NRXN3, NUPR1, OLFM1, OPTN, PALM, PAPPA, PDCD4, PDGFA, PITX2, PLXNC1, PLXND1, PMAIP1, POSTN, PPL, PPP3CC, PRELP, PRKG1, PRRX2, PSRC1, PTGER4, PTPRZ1, RACGAP1, RAD9A, RASGRP1, RCAN3, RELN, RHOB, RORA, S1PR1, SCN9A, SCRG1, SECTM1, SFRP1, SIX2, SLC2A14, SLIT2, SPOCK1, SRGN, STAT1, STIL, STMN1, SUV39H1, TACC3, TCF7L1, TFAP2A, TIMELESS, TLR4, TNFAIP8, TNFRSF10B, TNS3, TP53, TRAF5, TUFT1, WHSC1, ZNF423	1870	developmental process
GO:0010212	3.308e-02	1.528	7 BLM, BRCA2, MSH2, RAD54B, RAD54L, TOPBP1, TP53	23	response to ionizing radiation
GO:0007275	3.429e-02	83.5	111 ACAN, AGTR1, ALDH1A3, ANPEP, ASF1B, BAIAP2, BLM, BRCA1, BRCA2, BST1, CCL2, CCNF, CDH13, CDH4, CENPF, CIT, CLEC3B, COL13A1, COL4A2, COL8A1, COMP, DACT1, DFNA5, DHCR7, DMC1, DMD, DPYSL2, E2F1, EDIL3, EMX2, ENPP1, FANCG, FHL1, FOXE1, FOXF2, FST, FZD7, GATA2, GATA6, GINS1, GSTM3, HELLS, HMGB3, HOXA9, HOXB7, HOXC10, HOXC11, HTRA2, ID1, IL1A, IL6, ITGA2, ITGA8, JAG1, KIT, KLF9, LAMA2, LAMA5, LAMC2, LIG1, LIMK1, LMO2, LRP5, MBP, MEOX2, MEST, MGP, MMP14, MMP2, MSH2, NEDD4, NKX3-1, NPR3, NRG1, NRXN3, OLFM1, PDGFA, PITX2, PLXNC1, PLXND1, POSTN, PPL, PRELP, PRKG1, PRRX2, PTGER4, PTPRZ1, RELN, RHOB, RORA, S1PR1, SCN9A, SCRG1, SECTM1, SFRP1, SIX2, SLC2A14, SLIT2, SPOCK1, SRGN, STIL, STMN1, TACC3, TCF7L1, TFAP2A, TIMELESS, TLR4, TNS3, TP53, TUFT1, ZNF423	1257	multicellular organismal development
GO:0006323	3.449e-02	4.052	12 ASF1B, CHAF1A, CHAF1B, HMGA1, MCM2, NAP1L4, NCAPD3, NCAPG, NCAPG2, NCAPH, SMC2, SMC4	61	DNA packaging
GO:0048015	3.568e-02	2.989	10 AGTR1, AURKA, BUB1B, FEN1, NPR3, RFC4, S1PR1, SPAG5, UBE2C, ZWINT	45	phosphoinositide-mediated signaling
GO:0000084	3.938e-02	0.7971	5 BRCA2, CDT1, DDX11, POLA1, POLD1	12	S phase of mitotic cell cycle
GO:0000086	3.938e-02	0.7971	5 CDK2, CHEK1, DDX11, PKIA, TPD52L1	12	G2/M transition of mitotic cell cycle
GO:0032501	4.336e-02	107	136 ACAN, AGTR1, ALDH1A3, ANPEP, ASF1B, ATXN1, BAIAP2, BARD1, BLM, BRCA1, BRCA2, BST1, CALD1, CCL2, CCNF, CDH13, CDH4, CENPF, CIT, CLEC3B, COL13A1, COL4A2, COL8A1, COMP, CORIN, CYP1B1, DACT1, DFNA5, DHCR7, DMC1, DMD, DPYSL2, E2F1, EDIL3, EFEMP1, EMX2, ENPP1, F2R, FANCG, FHL1, FOXE1, FOXF2, FST, FZD7, GABBR2, GATA2, GATA6, GINS1, GSTM3, HELLS, HMGB3, HNMT, HOXA9, HOXB7, HOXC10, HOXC11, HTR1F, HTRA2, ID1, IL1A, IL6, ITGA2, ITGA8, JAG1, KCNN4, KIAA1199, KIT, KLF9, LAMA2, LAMA5, LAMC2, LIG1, LIMK1, LMO2, LRP5, MBP, MEOX2, MEST, MGP, MMP14, MMP2, MMP3, MSH2, MYL5, NEDD4, NKX3-1, NPR3, NPTX2, NRG1, NRXN3, OLFM1, OPN3, PDGFA, PENK, PITX2, PLXNC1, PLXND1, POSTN, PPL, PRELP, PRKG1, PROS1, PRRX2, PTGER4, PTPRZ1, RELN, RHOB, RORA, S1PR1, SCN9A, SCRG1, SECTM1, SFRP1, SIX2, SLC1A4, SLC25A4, SLC2A14, SLIT2, SNTB1, SPOCK1, SRGN, STIL, STMN1, TACC3, TCF7L1, TFAP2A, TFPI, TFPI2, TIMELESS, TLR4, TNS3, TNXB, TP53, TRPV2, TUFT1, ZNF423	1611	multicellular organismal process
GO:0006289	4.531e-02	3.122	10 BRCA2, LIG1, POLD1, POLD3, POLE, POLE2, RFC2, RFC3, RFC4, TP53	47	nucleotide-excision repair

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005694	1.455e-16	16.6	60 ASF1B, AURKB, BIRC5, BLM, BRCA1, BUB1, BUB1B, C18orf24, C21orf45, CDCA8, CDT1, CENPE, CENPF, CENPI, CENPM, CHEK1, DMC1, DSN1, ERCC6L, FANCI, HMGA1, HMGB3, KIF22, KIF2C, KNTC1, MAD2L1, MCM2, MCM3, MCM7, MLF1IP, NCAPD3, NCAPG, NCAPH, NEDD4, NUP85, OIP5, ORC6L, POLA1, POLA2, POLD3, PRIM1, RANGAP1, RFC2, RFC3, RFC4, SMC2, SMC4, SPAG5, SPC25, SUPT16H, SUV39H1, SUZ12, TELO2, TIMELESS, TIPIN, TMPO, TOPBP1, TP53, ZWILCH, ZWINT	248	chromosome
GO:0044427	1.590e-16	13.25	53 ASF1B, AURKB, BLM, BUB1, BUB1B, C18orf24, C21orf45, CDCA8, CDT1, CENPE, CENPF, CENPI, CENPM, CHEK1, DSN1, ERCC6L, HMGA1, KIF22, KIF2C, KNTC1, MAD2L1, MCM2, MCM3, MCM7, MLF1IP, NCAPD3, NCAPG, NCAPH, NEDD4, NUP85, OIP5, ORC6L, POLA1, POLA2, POLD3, PRIM1, RANGAP1, RFC2, RFC3, RFC4, SMC2, SMC4, SPAG5, SPC25, SUV39H1, SUZ12, TELO2, TIMELESS, TIPIN, TMPO, TP53, ZWILCH, ZWINT	198	chromosomal part
GO:0000793	5.229e-13	4.417	27 BLM, BRCA1, BUB1, BUB1B, C18orf24, CENPE, CENPF, CENPM, CHEK1, DMC1, DSN1, ERCC6L, KNTC1, MLF1IP, NCAPD3, NCAPG, NCAPH, NUP85, RANGAP1, SMC2, SMC4, SPAG5, SPC25, SUV39H1, TOPBP1, ZWILCH, ZWINT	66	condensed chromosome
GO:0000775	1.138e-11	4.217	25 AURKB, BUB1, BUB1B, C18orf24, C21orf45, CDCA8, CENPE, CENPF, CENPI, CENPM, DSN1, ERCC6L, KIF22, KIF2C, KNTC1, MAD2L1, MLF1IP, NUP85, OIP5, RANGAP1, SPAG5, SPC25, SUV39H1, ZWILCH, ZWINT	63	chromosome, centromeric region
GO:0005819	3.928e-09	5.354	25 AURKA, AURKB, BUB1, BUB1B, C18orf24, CDC20, CDC6, CENPE, CENPF, FAM29A, KIF11, KIF14, KIF15, KIF23, KIF4A, KIFC1, KNTC1, NEDD9, NUP85, PSRC1, RACGAP1, SPAG5, TPX2, TTK, TUBGCP5	80	spindle
GO:0000777	1.219e-08	2.276	16 BUB1, BUB1B, C18orf24, CENPE, CENPF, CENPM, DSN1, ERCC6L, KNTC1, MLF1IP, NUP85, RANGAP1, SPAG5, SPC25, ZWILCH, ZWINT	34	condensed chromosome kinetochore
GO:0000779	1.219e-08	2.276	16 BUB1, BUB1B, C18orf24, CENPE, CENPF, CENPM, DSN1, ERCC6L, KNTC1, MLF1IP, NUP85, RANGAP1, SPAG5, SPC25, ZWILCH, ZWINT	34	condensed chromosome, centromeric region
GO:0000776	3.262e-08	3.079	18 BUB1, BUB1B, C18orf24, CENPE, CENPF, CENPM, DSN1, ERCC6L, KIF22, KNTC1, MAD2L1, MLF1IP, NUP85, RANGAP1, SPAG5, SPC25, ZWILCH, ZWINT	46	kinetochore
GO:0005657	2.348e-07	1.74	13 BLM, CDT1, CHEK1, MCM3, MCM7, POLA1, POLA2, POLD3, PRIM1, RFC2, RFC3, RFC4, TP53	26	replication fork
GO:0000228	3.246e-05	5.154	19 BLM, BUB1, CHEK1, DMC1, MCM2, MCM3, MCM7, NCAPD3, ORC6L, POLA1, POLA2, POLD3, PRIM1, SMC2, SUV39H1, SUZ12, TIMELESS, TIPIN, TOPBP1	77	nuclear chromosome
GO:0043228	5.208e-05	89.62	132 ABHD4, ANK2, ANK3, ASF1B, ATF3, AURKA, AURKB, BACH1, BIRC5, BLM, BRCA1, BRCA2, BUB1, BUB1B, C18orf24, C21orf45, CALD1, CAMK2N1, CAPG, CDC20, CDC45L, CDC6, CDCA8, CDT1, CENPE, CENPF, CENPI, CENPM, CHEK1, CKAP2, CSTF2, DDX11, DDX54, DMC1, DMD, DPYSL2, DSN1, ERCC6L, ESPL1, EXOSC9, FAM29A, FANCI, FGFR1OP, FHOD3, FRMD4A, FRMD4B, GABARAPL3, GATA2, GSN, GTSE1, HIP1, HMGA1, HMGB3, IFT20, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, KNTC1, KRT18, LMNB1, LMNB2, MAD2L1, MCM2, MCM3, MCM4, MCM7, MKI67, MLF1IP, MRE11A, MYBL1, MYL5, MYO19, MYO1E, NCAPD3, NCAPG, NCAPH, NEDD4, NEDD9, NEK2, NUP85, OIP5, ORC6L, OSBPL10, PARP2, PLEK2, POLA1, POLA2, POLD3, PPL, PRIM1, PRKG1, PSRC1, RACGAP1, RAD9A, RANGAP1, RFC2, RFC3, RFC4, SMC2, SMC4, SNTB1, SPAG5, SPC25, STAT1, STAT4, STMN1, SUPT16H, SUV39H1, SUZ12, TELO2, TIMELESS, TIPIN, TMPO, TNS3, TOPBP1, TP53, TPX2, TRAF5, TTK, TUBGCP5, TYRO3, USP13, WDHD1, ZWILCH, ZWINT	1339	non-membrane-bounded organelle
GO:0043232	5.208e-05	89.62	132 ABHD4, ANK2, ANK3, ASF1B, ATF3, AURKA, AURKB, BACH1, BIRC5, BLM, BRCA1, BRCA2, BUB1, BUB1B, C18orf24, C21orf45, CALD1, CAMK2N1, CAPG, CDC20, CDC45L, CDC6, CDCA8, CDT1, CENPE, CENPF, CENPI, CENPM, CHEK1, CKAP2, CSTF2, DDX11, DDX54, DMC1, DMD, DPYSL2, DSN1, ERCC6L, ESPL1, EXOSC9, FAM29A, FANCI, FGFR1OP, FHOD3, FRMD4A, FRMD4B, GABARAPL3, GATA2, GSN, GTSE1, HIP1, HMGA1, HMGB3, IFT20, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, KNTC1, KRT18, LMNB1, LMNB2, MAD2L1, MCM2, MCM3, MCM4, MCM7, MKI67, MLF1IP, MRE11A, MYBL1, MYL5, MYO19, MYO1E, NCAPD3, NCAPG, NCAPH, NEDD4, NEDD9, NEK2, NUP85, OIP5, ORC6L, OSBPL10, PARP2, PLEK2, POLA1, POLA2, POLD3, PPL, PRIM1, PRKG1, PSRC1, RACGAP1, RAD9A, RANGAP1, RFC2, RFC3, RFC4, SMC2, SMC4, SNTB1, SPAG5, SPC25, STAT1, STAT4, STMN1, SUPT16H, SUV39H1, SUZ12, TELO2, TIMELESS, TIPIN, TMPO, TNS3, TOPBP1, TP53, TPX2, TRAF5, TTK, TUBGCP5, TYRO3, USP13, WDHD1, ZWILCH, ZWINT	1339	intracellular non-membrane-bounded organelle
GO:0005654	6.186e-05	37.82	68 ANKRD1, ATXN1, BLM, BRCA1, BRCA2, CCNA2, CCNE1, CCNE2, CCNL1, CDC20, CDC25A, CDC45L, CDC6, CDC7, CDK2, CDT1, CHAF1A, CHAF1B, CHEK1, DNA2, E2F1, E2F8, EZH2, FOXF2, GMNN, HMGA1, KIF20B, KIF23, LIG1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MRE11A, NAP1L4, OIP5, ORC1L, ORC6L, PARP2, PITX2, PKMYT1, POLA1, POLA2, POLD1, POLD3, POLE, POLE2, POLQ, POLR3K, PRIM1, PRKAG2, RAD51, RBL1, RFC2, RFC3, RFC4, SUPT16H, SUV39H1, SUZ12, TDG, TOE1, TOPBP1, TP53, UBE2C, WDHD1	565	nucleoplasm
GO:0005576	8.080e-05	45.04	77 ACAN, ASPN, C1orf54, C1QTNF3, CCL2, CDH13, CFHR1, CLEC3B, COL13A1, COL21A1, COL4A1, COL4A2, COL4A5, COL8A1, COMP, CPA4, ECM2, EDIL3, EFEMP1, ENPP1, FOLR3, GDF15, GPC4, GREM2, GSN, HEG1, ICAM1, IL13RA2, IL1A, IL6, ISLR, ITGBL1, JAG1, KIT, LAMA2, LAMA5, LAMC2, LGALS3BP, LIPG, MGP, MMP14, MMP2, MMP3, NBL1, NID2, NOV, NPTX2, NRG1, PAPPA, PCOLCE2, PDGFA, PDGFRL, PENK, POSTN, PRELP, PROS1, PRSS12, PTX3, RELN, RNASET2, SCRG1, SECTM1, SFRP1, SLIT2, SORD, SPINT2, SPOCK1, SPON1, SRGN, ST3GAL4, TFPI, TFPI2, THBS2, TINAGL1, TNFSF4, TNXB, TUFT1	673	extracellular region
GO:0005578	1.595e-04	10.24	27 ACAN, ASPN, COL13A1, COL21A1, COL4A1, COL4A2, COL4A5, COL8A1, COMP, ECM2, EFEMP1, GPC4, LAMA2, LAMA5, LAMC2, LGALS3BP, MGP, MMP14, MMP2, MMP3, NID2, PRELP, RELN, SPOCK1, SPON1, TFPI2, TNXB	153	proteinaceous extracellular matrix
GO:0031012	1.787e-04	10.91	28 ACAN, ASPN, COL13A1, COL21A1, COL4A1, COL4A2, COL4A5, COL8A1, COMP, ECM2, EFEMP1, GPC4, LAMA2, LAMA5, LAMC2, LGALS3BP, MGP, MMP14, MMP2, MMP3, NID2, PRELP, RELN, SPINT2, SPOCK1, SPON1, TFPI2, TNXB	163	extracellular matrix
GO:0031981	3.306e-04	57.43	90 ABHD4, ANKRD1, ATF3, ATXN1, BACH1, BIRC5, BLM, BRCA1, BRCA2, CCNA2, CCNE1, CCNE2, CCNL1, CDC20, CDC25A, CDC45L, CDC6, CDC7, CDK2, CDT1, CENPF, CHAF1A, CHAF1B, CHEK1, CSTF2, DDX11, DDX54, DNA2, E2F1, E2F8, EXOSC9, EZH2, FOXF2, GATA2, GMNN, HMGA1, KIF20B, KIF23, KIF4A, LIG1, LMNB1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MKI67, MRE11A, MYBL1, NAP1L4, OIP5, ORC1L, ORC6L, OSBPL10, PARP2, PITX2, PKMYT1, POLA1, POLA2, POLD1, POLD3, POLE, POLE2, POLQ, POLR3K, PRIM1, PRKAG2, PRKG1, RAD51, RAD9A, RBL1, RFC2, RFC3, RFC4, STAT1, STAT4, SUPT16H, SUV39H1, SUZ12, TDG, TNS3, TOE1, TOPBP1, TP53, TYRO3, UBE2C, USP13, WDHD1	858	nuclear lumen
GO:0000796	3.938e-04	0.4016	5 NCAPD3, NCAPG, NCAPH, SMC2, SMC4	6	condensin complex
GO:0044454	7.753e-04	3.815	14 BLM, BUB1, MCM2, MCM3, MCM7, NCAPD3, ORC6L, POLA1, POLA2, POLD3, PRIM1, SUZ12, TIMELESS, TIPIN	57	nuclear chromosome part
GO:0015630	8.595e-04	21.48	42 AURKA, AURKB, BRCA1, BRCA2, BUB1, BUB1B, C18orf24, CDC20, CDC45L, CDC6, CENPE, CENPF, CKAP2, ESPL1, FAM29A, FGFR1OP, GABARAPL3, GTSE1, IFT20, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, KNTC1, KRT18, NEDD9, NEK2, NUP85, PSRC1, RACGAP1, SPAG5, STMN1, TPX2, TRAF5, TTK, TUBGCP5	321	microtubule cytoskeleton
GO:0005634	9.123e-04	204.7	250 ABHD4, ANKRD1, ARHGAP19, ARID5B, ARL4C, ARNTL2, ASF1B, ASPM, ATAD2, ATF3, ATXN1, AURKA, AURKB, AUTS2, BACH1, BARD1, BCAS3, BEX4, BIRC5, BLM, BRCA1, BRCA2, BRIP1, BUB1, BUB1B, C21orf45, CA9, CAPG, CCNA2, CCND3, CCNE1, CCNE2, CCNF, CCNL1, CDC20, CDC25A, CDC45L, CDC6, CDC7, CDCA4, CDCA8, CDK2, CDKN2D, CDT1, CENPE, CENPF, CENPI, CENPM, CHAF1A, CHAF1B, CHEK1, CPA3, CSTF2, DACT1, DCK, DCLRE1B, DCLRE1C, DDX11, DDX12, DDX54, DEPDC1, DHCR7, DMC1, DMD, DNA2, DSCC1, DSN1, DTL, E2F1, E2F8, ESPL1, ETV1, EXO1, EXOSC9, EZH2, FANCA, FANCG, FANCI, FEN1, FHL1, FOXE1, FOXF2, FOXM1, FOXN3, GALE, GATA2, GATA6, GINS1, GINS2, GINS3, GINS4, GMNN, GNPTAB, HELLS, HIP1, HIVEP1, HJURP, HMGA1, HMGB3, HOXA9, HOXB7, HOXC10, HOXC11, HTRA2, ID1, KHSRP, KIF11, KIF14, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, KIT, KLF9, KNTC1, LGALS3BP, LIG1, LIMK1, LMCD1, LMNB1, LMNB2, LMO2, LSM2, LUZP1, MAD2L1, MANSC1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MDM1, MEOX2, MEX3D, MKI67, MLF1IP, MRE11A, MSC, MSH2, MYBL1, MYCT1, NAP1L4, NCAPD3, NCAPG, NCAPG2, NCAPH, NCOA3, NEDD9, NEK2, NET1, NKX3-1, NR1D1, NRG1, NUP155, NUP85, NUPR1, OIP5, ORC1L, ORC6L, OSBPL10, PARP2, PDCD4, PER3, PIR, PITX2, PKIA, PKMYT1, PLEK2, PNMA2, POLA1, POLA2, POLD1, POLD3, POLE, POLE2, POLQ, POLR3K, PPL, PRIM1, PRKAG2, PRKG1, PROS1, PRRX2, PSMB9, PSMC3IP, PTGES, RACGAP1, RAD51, RAD51AP1, RAD54B, RAD54L, RAD9A, RANGAP1, RBL1, RFC2, RFC3, RFC4, RMI1, RNASEH2A, RORA, RRAGB, SIX2, SMC2, SMC4, SPC25, SREBF2, SSX2IP, STAT1, STAT4, SUPT16H, SUV39H1, SUZ12, TBC1D1, TCF7L1, TDG, TELO2, TFAP2A, TFPI, TIMELESS, TIPIN, TMEM38B, TMPO, TNS3, TOE1, TOPBP1, TP53, TPX2, TRIM22, TRIP13, TSC22D1, TYRO3, UBE2C, UBR7, UNG, USP13, VRK1, WDHD1, WHSC1, XBP1, ZNF273, ZNF394, ZNF395, ZNF423, ZNF536, ZNF85, ZWINT	3059	nucleus
GO:0044428	1.003e-03	75.3	109 ABHD4, ANKRD1, ATF3, ATXN1, BACH1, BARD1, BIRC5, BLM, BRCA1, BRCA2, BUB1, BUB1B, CCNA2, CCNE1, CCNE2, CCNL1, CDC20, CDC25A, CDC45L, CDC6, CDC7, CDK2, CDT1, CENPF, CHAF1A, CHAF1B, CHEK1, CSTF2, DDX11, DDX54, DHCR7, DMC1, DNA2, DTL, E2F1, E2F8, EXOSC9, EZH2, FOXF2, GATA2, GMNN, HMGA1, HOXC10, KIF20B, KIF23, KIF4A, LIG1, LMNB1, LSM2, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MKI67, MRE11A, MSH2, MYBL1, NAP1L4, NCAPD3, NUP155, NUP85, OIP5, ORC1L, ORC6L, OSBPL10, PARP2, PITX2, PKMYT1, POLA1, POLA2, POLD1, POLD3, POLE, POLE2, POLQ, POLR3K, PRIM1, PRKAG2, PRKG1, PTGES, RAD51, RAD9A, RANGAP1, RBL1, RFC2, RFC3, RFC4, SMC2, STAT1, STAT4, SUPT16H, SUV39H1, SUZ12, TDG, TIMELESS, TIPIN, TMEM38B, TMPO, TNS3, TOE1, TOPBP1, TP53, TYRO3, UBE2C, USP13, WDHD1	1125	nuclear part
GO:0043596	1.341e-03	0.7362	6 MCM3, MCM7, POLA1, POLA2, POLD3, PRIM1	11	nuclear replication fork
GO:0044421	1.744e-03	25.17	46 ACAN, ASPN, CCL2, CDH13, CFHR1, COL13A1, COL21A1, COL4A1, COL4A2, COL4A5, COL8A1, COMP, ECM2, EFEMP1, ENPP1, GDF15, GPC4, GREM2, ICAM1, IL13RA2, IL1A, IL6, KIT, LAMA2, LAMA5, LAMC2, LGALS3BP, MGP, MMP14, MMP2, MMP3, NID2, PDGFA, PRELP, RELN, SCRG1, SECTM1, SFRP1, SORD, SPINT2, SPOCK1, SPON1, SRGN, TFPI2, TNFSF4, TNXB	376	extracellular region part
GO:0044430	2.776e-03	27.98	49 AURKA, AURKB, BRCA1, BRCA2, BUB1, BUB1B, C18orf24, CAMK2N1, CAPG, CDC20, CDC45L, CDC6, CENPE, CENPF, CKAP2, ESPL1, FAM29A, FGFR1OP, GABARAPL3, GTSE1, IFT20, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, KNTC1, KRT18, LMNB1, LMNB2, MYL5, MYO19, MYO1E, NEDD9, NEK2, NUP85, PSRC1, RACGAP1, SPAG5, STMN1, TPX2, TRAF5, TTK, TUBGCP5	418	cytoskeletal part
GO:0005658	3.594e-03	0.3347	4 MCM3, POLA1, POLA2, PRIM1	5	alpha DNA polymerase:primase complex
GO:0030935	3.594e-03	0.3347	4 COL4A1, COL4A2, COL4A5, COL8A1	5	sheet-forming collagen
GO:0030894	4.843e-03	0.6024	5 MCM3, POLA1, POLA2, POLD3, PRIM1	9	replisome
GO:0043601	4.843e-03	0.6024	5 MCM3, POLA1, POLA2, POLD3, PRIM1	9	nuclear replisome
GO:0000794	7.142e-03	1.339	7 BLM, BUB1, CHEK1, DMC1, NCAPD3, SUV39H1, TOPBP1	20	condensed nuclear chromosome
GO:0000940	9.703e-03	0.2008	3 BUB1B, CENPE, CENPF	3	outer kinetochore of condensed chromosome
GO:0005587	2.958e-02	0.2677	3 COL4A1, COL4A2, COL4A5	4	collagen type IV
GO:0000922	3.706e-02	1.339	6 BUB1, CENPF, KIF11, KNTC1, TPX2, TUBGCP5	20	spindle pole
GO:0031974	3.863e-02	73.16	97 ABHD4, ANKRD1, ATF3, ATXN1, BACH1, BIRC5, BLM, BRCA1, BRCA2, CCNA2, CCNE1, CCNE2, CCNL1, CDC20, CDC25A, CDC45L, CDC6, CDC7, CDK2, CDT1, CENPF, CHAF1A, CHAF1B, CHEK1, CSTF2, DDX11, DDX54, DNA2, E2F1, E2F8, EXOSC9, EZH2, FOXF2, GATA2, GMNN, HMGA1, HTRA2, KIF20B, KIF23, KIF4A, LIG1, LMNB1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MKI67, MRE11A, MYBL1, NAP1L4, OIP5, OLFM1, ORC1L, ORC6L, OSBPL10, PARP2, PDGFA, PITX2, PKMYT1, POLA1, POLA2, POLD1, POLD3, POLE, POLE2, POLQ, POLR3K, PRIM1, PRKAG2, PRKG1, PTGES, PTGIS, RAD51, RAD9A, RBL1, RCN1, RFC2, RFC3, RFC4, STAT1, STAT4, SUPT16H, SUV39H1, SUZ12, TDG, THBS2, TNS3, TOE1, TOPBP1, TP53, TYRO3, UBE2C, USP13, WDHD1	1093	membrane-enclosed lumen
GO:0043233	3.997e-02	71.48	95 ABHD4, ANKRD1, ATF3, ATXN1, BACH1, BIRC5, BLM, BRCA1, BRCA2, CCNA2, CCNE1, CCNE2, CCNL1, CDC20, CDC25A, CDC45L, CDC6, CDC7, CDK2, CDT1, CENPF, CHAF1A, CHAF1B, CHEK1, CSTF2, DDX11, DDX54, DNA2, E2F1, E2F8, EXOSC9, EZH2, FOXF2, GATA2, GMNN, HMGA1, KIF20B, KIF23, KIF4A, LIG1, LMNB1, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MKI67, MRE11A, MYBL1, NAP1L4, OIP5, OLFM1, ORC1L, ORC6L, OSBPL10, PARP2, PDGFA, PITX2, PKMYT1, POLA1, POLA2, POLD1, POLD3, POLE, POLE2, POLQ, POLR3K, PRIM1, PRKAG2, PRKG1, PTGIS, RAD51, RAD9A, RBL1, RCN1, RFC2, RFC3, RFC4, STAT1, STAT4, SUPT16H, SUV39H1, SUZ12, TDG, THBS2, TNS3, TOE1, TOPBP1, TP53, TYRO3, UBE2C, USP13, WDHD1	1068	organelle lumen
GO:0005604	4.938e-02	2.41	8 COL4A1, COL4A2, COL4A5, COL8A1, LAMA2, LAMA5, LAMC2, NID2	36	basement membrane

Id	Pvalue	ExpCount	Count	Size	Term
GO:0003777	2.846e-03	2.411	11 CENPE, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1	37	microtubule motor activity
GO:0008094	3.575e-03	2.477	11 BLM, BRIP1, DDX11, DDX12, DMC1, DNA2, RAD51, RAD54B, RFC2, RFC3, RFC4	38	DNA-dependent ATPase activity
GO:0003887	1.097e-02	1.173	7 POLA1, POLA2, POLD1, POLD3, POLE, POLE2, POLQ	18	DNA-directed DNA polymerase activity
GO:0003774	1.611e-02	4.562	14 CENPE, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, MYL5, MYO19, MYO1E	70	motor activity
GO:0003678	2.013e-02	2.151	9 BLM, BRIP1, DDX11, DDX12, DNA2, MCM4, MCM6, MCM7, RAD54B	33	DNA helicase activity
GO:0046870	2.434e-02	0.391	4 MT1G, MT1H, MT1M, MT1X	6	cadmium ion binding
GO:0034061	2.502e-02	1.369	7 POLA1, POLA2, POLD1, POLD3, POLE, POLE2, POLQ	21	DNA polymerase activity
GO:0005201	2.713e-02	2.737	10 ACAN, COL4A1, COL4A2, COL4A5, COMP, MGP, PRELP, TFPI2, TINAGL1, TUFT1	42	extracellular matrix structural constituent
GO:0004527	2.876e-02	2.281	9 DCLRE1C, ENPP1, ERI2, EXO1, EXOSC9, FEN1, MRE11A, POLD1, RAD9A	35	exonuclease activity
GO:0030554	3.628e-02	55.72	80 ABCA5, ABCA8, AOX1, ATAD2, AURKA, AURKB, BLM, BRIP1, BUB1, BUB1B, CDC6, CDC7, CDK2, CENPE, CHEK1, CIT, DCK, DDX11, DDX12, DDX54, DMC1, DNA2, ENPP1, EPHA5, ERCC6L, GALNAC4S-6ST, HELLS, HSPA14, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, KIT, LIG1, LIMK1, MAP3K8, MCM2, MCM3, MCM5, MCM6, MCM7, MKI67, MSH2, MYO19, MYO1E, NEK2, NUAK1, ORC1L, PAK4, PDE10A, PDGFRB, PKMYT1, PLK4, POLQ, PRKAG2, PRKG1, RAD54B, RAD54L, RFC2, RFC4, ROR1, SMC2, SMC4, SQLE, STEAP1, STK38L, TP53, TPX2, TRIP13, TTK, TYRO3, UBA7, UBE2C, VRK1	855	adenyl nucleotide binding
GO:0032559	4.314e-02	52.79	76 ABCA5, ABCA8, ATAD2, AURKA, AURKB, BLM, BRIP1, BUB1, BUB1B, CDC6, CDC7, CDK2, CENPE, CHEK1, CIT, DCK, DDX11, DDX12, DDX54, DMC1, DNA2, ENPP1, EPHA5, ERCC6L, HELLS, HSPA14, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, KIT, LIG1, LIMK1, MAP3K8, MCM2, MCM3, MCM5, MCM6, MCM7, MKI67, MSH2, MYO19, MYO1E, NEK2, NUAK1, ORC1L, PAK4, PDE10A, PDGFRB, PKMYT1, PLK4, POLQ, PRKAG2, PRKG1, RAD54B, RAD54L, RFC2, RFC4, ROR1, SMC2, SMC4, STK38L, TP53, TPX2, TRIP13, TTK, TYRO3, UBA7, UBE2C, VRK1	810	adenyl ribonucleotide binding
GO:0005524	4.774e-02	52.2	75 ABCA5, ABCA8, ATAD2, AURKA, AURKB, BLM, BRIP1, BUB1, BUB1B, CDC6, CDC7, CDK2, CENPE, CHEK1, CIT, DCK, DDX11, DDX12, DDX54, DMC1, DNA2, ENPP1, EPHA5, ERCC6L, HELLS, HSPA14, KIF11, KIF14, KIF15, KIF18B, KIF20B, KIF22, KIF23, KIF2C, KIF4A, KIFC1, KIT, LIG1, LIMK1, MAP3K8, MCM2, MCM3, MCM5, MCM6, MCM7, MKI67, MSH2, MYO19, MYO1E, NEK2, NUAK1, ORC1L, PAK4, PDGFRB, PKMYT1, PLK4, POLQ, PRKAG2, PRKG1, RAD54B, RAD54L, RFC2, RFC4, ROR1, SMC2, SMC4, STK38L, TP53, TPX2, TRIP13, TTK, TYRO3, UBA7, UBE2C, VRK1	801	ATP binding

Id	Pvalue	ExpCount	Count	Size	Term
03030	1.645e-12	2.406	20 DNA2, FEN1, LIG1, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, POLA1, POLA2, POLD1, POLD3, POLE, POLE2, PRIM1, RFC2, RFC3, RFC4, RNASEH2A	33	DNA replication
04110	2.735e-08	7.146	28 BUB1, BUB1B, CCNA2, CCND3, CCNE1, CCNE2, CDC20, CDC25A, CDC45L, CDC6, CDC7, CDK2, CDKN2D, CHEK1, E2F1, ESPL1, MAD2L1, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, ORC1L, ORC6L, PKMYT1, RBL1, TP53	98	Cell cycle
04512	4.775e-03	4.229	14 COL4A1, COL4A2, COMP, HMMR, ITGA2, ITGA8, LAMA2, LAMA5, LAMC2, RELN, SDC1, SDC2, THBS2, TNXB	58	ECM-receptor interaction
03430	8.544e-03	1.604	8 EXO1, LIG1, MSH2, POLD1, POLD3, RFC2, RFC3, RFC4	22	Mismatch repair
03410	1.469e-02	2.188	9 FEN1, LIG1, PARP2, POLD1, POLD3, POLE, POLE2, TDG, UNG	30	Base excision repair
03440	1.922e-02	1.823	8 BLM, BRCA2, MRE11A, POLD1, POLD3, RAD51, RAD54B, RAD54L	25	Homologous recombination
01430	4.594e-02	4.302	12 COL4A1, COL4A2, COMP, KRT18, LAMA2, LAMA5, LAMC2, LMNB1, LMNB2, RELN, THBS2, TNXB	59	Cell junctions

No enriched terms

No enriched terms

Entrez genes

ABCA5ATP-binding cassette, sub-family A (ABC1), member 5 (213353_at), score: -0.58 ABCA8ATP-binding cassette, sub-family A (ABC1), member 8 (204719_at), score: -0.62 ABHD11abhydrolase domain containing 11 (221927_s_at), score: 0.5 ABHD4abhydrolase domain containing 4 (218581_at), score: -0.6 ACANaggrecan (205679_x_at), score: -0.67 AGPAT51-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) (218096_at), score: 0.48 AGTR1angiotensin II receptor, type 1 (205357_s_at), score: -0.58 ALDH1A3aldehyde dehydrogenase 1 family, member A3 (203180_at), score: 0.5 ANK2ankyrin 2, neuronal (202920_at), score: -0.58 ANK3ankyrin 3, node of Ranvier (ankyrin G) (206385_s_at), score: -0.6 ANKRD1ankyrin repeat domain 1 (cardiac muscle) (206029_at), score: -0.74 ANPEPalanyl (membrane) aminopeptidase (202888_s_at), score: 0.49 ANXA3annexin A3 (209369_at), score: -0.78 AOX1aldehyde oxidase 1 (205083_at), score: -0.74 APOBEC3Bapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B (206632_s_at), score: 0.51 ARHGAP11ARho GTPase activating protein 11A (204492_at), score: 0.53 ARHGAP19Rho GTPase activating protein 19 (212738_at), score: 0.55 ARID5BAT rich interactive domain 5B (MRF1-like) (212614_at), score: -0.6 ARL4CADP-ribosylation factor-like 4C (202207_at), score: -0.63 ARNTL2aryl hydrocarbon receptor nuclear translocator-like 2 (220658_s_at), score: 0.6 ASF1BASF1 anti-silencing function 1 homolog B (S. cerevisiae) (218115_at), score: 0.67 ASNSasparagine synthetase (205047_s_at), score: -0.55 ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila) (219918_s_at), score: 0.52 ASPNasporin (219087_at), score: -0.56 ATAD2ATPase family, AAA domain containing 2 (218782_s_at), score: 0.59 ATF3activating transcription factor 3 (202672_s_at), score: -0.69 ATP6V0E2ATPase, H+ transporting V0 subunit e2 (213587_s_at), score: -0.54 ATXN1ataxin 1 (203232_s_at), score: -0.73 AURKAaurora kinase A (208079_s_at), score: 0.54 AURKBaurora kinase B (209464_at), score: 0.62 AUTS2autism susceptibility candidate 2 (212599_at), score: 0.59 B3GALT2UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 (217452_s_at), score: -0.82 BACE2beta-site APP-cleaving enzyme 2 (217867_x_at), score: 0.55 BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 1 (204194_at), score: -0.54 BAIAP2BAI1-associated protein 2 (205294_at), score: 0.51 BARD1BRCA1 associated RING domain 1 (205345_at), score: 0.71 BCAS3breast carcinoma amplified sequence 3 (220488_s_at), score: -0.53 BEX4brain expressed, X-linked 4 (215440_s_at), score: -0.55 BIRC5baculoviral IAP repeat-containing 5 (202095_s_at), score: 0.5 BLMBloom syndrome (205733_at), score: 0.55 BRCA1breast cancer 1, early onset (204531_s_at), score: 0.57 BRCA2breast cancer 2, early onset (208368_s_at), score: 0.48 BRIP1BRCA1 interacting protein C-terminal helicase 1 (221703_at), score: 0.49 BST1bone marrow stromal cell antigen 1 (205715_at), score: -0.88 BTN3A3butyrophilin, subfamily 3, member A3 (204820_s_at), score: -0.58 BUB1budding uninhibited by benzimidazoles 1 homolog (yeast) (209642_at), score: 0.53 BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast) (203755_at), score: 0.48 C13orf27chromosome 13 open reading frame 27 (213346_at), score: 0.61 C14orf1chromosome 14 open reading frame 1 (217188_s_at), score: -0.62 C16orf53chromosome 16 open reading frame 53 (218300_at), score: 0.49 C17orf91chromosome 17 open reading frame 91 (214696_at), score: -0.66 C18orf24chromosome 18 open reading frame 24 (217640_x_at), score: 0.54 C1orf112chromosome 1 open reading frame 112 (220840_s_at), score: 0.5 C1orf135chromosome 1 open reading frame 135 (220011_at), score: 0.55 C1orf54chromosome 1 open reading frame 54 (219506_at), score: -0.75 C1QTNF3C1q and tumor necrosis factor related protein 3 (220988_s_at), score: 0.48 C21orf45chromosome 21 open reading frame 45 (219004_s_at), score: 0.71 C4orf15chromosome 4 open reading frame 15 (210054_at), score: 0.5 C4orf18chromosome 4 open reading frame 18 (219872_at), score: -0.68 C5orf23chromosome 5 open reading frame 23 (219054_at), score: 0.58 C5orf30chromosome 5 open reading frame 30 (221823_at), score: 0.48 C7orf10chromosome 7 open reading frame 10 (219655_at), score: -0.77 C9orf40chromosome 9 open reading frame 40 (218904_s_at), score: 0.6 CA12carbonic anhydrase XII (203963_at), score: 0.69 CA9carbonic anhydrase IX (205199_at), score: 0.51 CALD1caldesmon 1 (201616_s_at), score: -0.58 CAMK2N1calcium/calmodulin-dependent protein kinase II inhibitor 1 (218309_at), score: 0.72 CAPGcapping protein (actin filament), gelsolin-like (201850_at), score: 0.5 CASP2caspase 2, apoptosis-related cysteine peptidase (209811_at), score: 0.5 CCDC15coiled-coil domain containing 15 (220466_at), score: 0.63 CCDC21coiled-coil domain containing 21 (219611_s_at), score: 0.47 CCDC81coiled-coil domain containing 81 (220389_at), score: -0.62 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: -0.78 CCNA2cyclin A2 (203418_at), score: 0.58 CCND3cyclin D3 (201700_at), score: 0.54 CCNE1cyclin E1 (213523_at), score: 0.57 CCNE2cyclin E2 (205034_at), score: 0.73 CCNFcyclin F (204826_at), score: 0.48 CCNL1cyclin L1 (220046_s_at), score: -0.59 CCR10chemokine (C-C motif) receptor 10 (220565_at), score: -0.55 CDC20cell division cycle 20 homolog (S. cerevisiae) (202870_s_at), score: 0.49 CDC25Acell division cycle 25 homolog A (S. pombe) (204695_at), score: 0.71 CDC45LCDC45 cell division cycle 45-like (S. cerevisiae) (204126_s_at), score: 0.58 CDC6cell division cycle 6 homolog (S. cerevisiae) (203967_at), score: 0.66 CDC7cell division cycle 7 homolog (S. cerevisiae) (204510_at), score: 0.62 CDCA3cell division cycle associated 3 (221436_s_at), score: 0.49 CDCA4cell division cycle associated 4 (218399_s_at), score: 0.49 CDCA8cell division cycle associated 8 (221520_s_at), score: 0.59 CDH13cadherin 13, H-cadherin (heart) (204726_at), score: -0.61 CDH4cadherin 4, type 1, R-cadherin (retinal) (220227_at), score: 0.67 CDK2cyclin-dependent kinase 2 (204252_at), score: 0.68 CDKN2Dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) (210240_s_at), score: 0.56 CDT1chromatin licensing and DNA replication factor 1 (209832_s_at), score: 0.78 CENPEcentromere protein E, 312kDa (205046_at), score: 0.56 CENPFcentromere protein F, 350/400ka (mitosin) (207828_s_at), score: 0.53 CENPIcentromere protein I (214804_at), score: 0.59 CENPMcentromere protein M (218741_at), score: 0.59 CERKceramide kinase (218421_at), score: 0.6 CFHR1complement factor H-related 1 (215388_s_at), score: -0.58 CHAF1Achromatin assembly factor 1, subunit A (p150) (214426_x_at), score: 0.68 CHAF1Bchromatin assembly factor 1, subunit B (p60) (204775_at), score: 0.63 CHEK1CHK1 checkpoint homolog (S. pombe) (205393_s_at), score: 0.51 CHPT1choline phosphotransferase 1 (221675_s_at), score: 0.55 CITcitron (rho-interacting, serine/threonine kinase 21) (212801_at), score: 0.67 CKAP2cytoskeleton associated protein 2 (218252_at), score: 0.53 CLEC3BC-type lectin domain family 3, member B (205200_at), score: -0.79 CLGNcalmegin (205830_at), score: 0.72 CLIP3CAP-GLY domain containing linker protein 3 (212358_at), score: -0.56 COBLL1COBL-like 1 (203642_s_at), score: -0.76 COL13A1collagen, type XIII, alpha 1 (211343_s_at), score: 0.65 COL21A1collagen, type XXI, alpha 1 (208096_s_at), score: -0.63 COL4A1collagen, type IV, alpha 1 (211981_at), score: -0.65 COL4A2collagen, type IV, alpha 2 (211966_at), score: -0.54 COL4A5collagen, type IV, alpha 5 (213110_s_at), score: -0.73 COL8A1collagen, type VIII, alpha 1 (214587_at), score: -0.67 COMPcartilage oligomeric matrix protein (205713_s_at), score: 0.5 CORINcorin, serine peptidase (220356_at), score: -0.75 CPA3carboxypeptidase A3 (mast cell) (205624_at), score: -0.57 CPA4carboxypeptidase A4 (205832_at), score: -0.59 CSTF2cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa (204459_at), score: 0.49 CTSCcathepsin C (201487_at), score: -0.63 CYFIP2cytoplasmic FMR1 interacting protein 2 (215785_s_at), score: -0.77 CYP1B1cytochrome P450, family 1, subfamily B, polypeptide 1 (202436_s_at), score: -0.65 DAAM1dishevelled associated activator of morphogenesis 1 (216060_s_at), score: -0.56 DAAM2dishevelled associated activator of morphogenesis 2 (212793_at), score: -0.72 DACT1dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) (219179_at), score: -0.71 DBNDD2dysbindin (dystrobrevin binding protein 1) domain containing 2 (218094_s_at), score: -0.58 DCKdeoxycytidine kinase (203302_at), score: 0.69 DCLRE1BDNA cross-link repair 1B (PSO2 homolog, S. cerevisiae) (219490_s_at), score: 0.59 DCLRE1CDNA cross-link repair 1C (PSO2 homolog, S. cerevisiae) (222233_s_at), score: 0.48 DDX11DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (208149_x_at), score: 0.58 DDX12DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) (213378_s_at), score: 0.52 DDX54DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 (219111_s_at), score: 0.56 DEPDC1DEP domain containing 1 (220295_x_at), score: 0.51 DEPDC6DEP domain containing 6 (218858_at), score: -0.62 DFNA5deafness, autosomal dominant 5 (203695_s_at), score: -0.56 DHCR77-dehydrocholesterol reductase (201790_s_at), score: -0.63 DHRS12dehydrogenase/reductase (SDR family) member 12 (204800_s_at), score: -0.53 DIRAS3DIRAS family, GTP-binding RAS-like 3 (215506_s_at), score: 0.56 DLEU2deleted in lymphocytic leukemia 2 (non-protein coding) (216870_x_at), score: 0.6 DLEU2Ldeleted in lymphocytic leukemia 2-like (215629_s_at), score: 0.65 DMC1DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) (208382_s_at), score: 0.53 DMDdystrophin (203881_s_at), score: -0.96 DNA2DNA replication helicase 2 homolog (yeast) (213647_at), score: 0.61 DNAJC9DnaJ (Hsp40) homolog, subfamily C, member 9 (213088_s_at), score: 0.55 DPY19L2P2dpy-19-like 2 pseudogene 2 (C. elegans) (215143_at), score: 0.54 DPYSL2dihydropyrimidinase-like 2 (200762_at), score: -0.6 DRAMdamage-regulated autophagy modulator (218627_at), score: -0.69 DSCC1defective in sister chromatid cohesion 1 homolog (S. cerevisiae) (219000_s_at), score: 0.61 DSN1DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) (219512_at), score: 0.72 DTLdenticleless homolog (Drosophila) (218585_s_at), score: 0.68 E2F1E2F transcription factor 1 (204947_at), score: 0.5 E2F8E2F transcription factor 8 (219990_at), score: 0.5 ECH1enoyl Coenzyme A hydratase 1, peroxisomal (200789_at), score: -0.56 ECM2extracellular matrix protein 2, female organ and adipocyte specific (206101_at), score: -0.56 EDIL3EGF-like repeats and discoidin I-like domains 3 (207379_at), score: -0.82 EFEMP1EGF-containing fibulin-like extracellular matrix protein 1 (201842_s_at), score: -0.69 EIF2S3eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa (205321_at), score: -0.78 EMP2epithelial membrane protein 2 (204975_at), score: 0.63 EMX2empty spiracles homeobox 2 (221950_at), score: 0.57 ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 (205066_s_at), score: 0.81 EPHA5EPH receptor A5 (215664_s_at), score: -0.67 ERCC6Lexcision repair cross-complementing rodent repair deficiency, complementation group 6-like (219650_at), score: 0.55 ERI2exoribonuclease 2 (213365_at), score: 0.57 ESPL1extra spindle pole bodies homolog 1 (S. cerevisiae) (38158_at), score: 0.54 ETV1ets variant 1 (221911_at), score: 0.48 EXO1exonuclease 1 (204603_at), score: 0.64 EXOSC9exosome component 9 (205061_s_at), score: 0.7 EZH2enhancer of zeste homolog 2 (Drosophila) (203358_s_at), score: 0.69 F2Rcoagulation factor II (thrombin) receptor (203989_x_at), score: -0.75 FAM111Afamily with sequence similarity 111, member A (218248_at), score: 0.52 FAM29Afamily with sequence similarity 29, member A (218602_s_at), score: 0.53 FAM8A1family with sequence similarity 8, member A1 (203420_at), score: -0.59 FANCAFanconi anemia, complementation group A (203805_s_at), score: 0.54 FANCGFanconi anemia, complementation group G (203564_at), score: 0.62 FANCIFanconi anemia, complementation group I (213007_at), score: 0.49 FEN1flap structure-specific endonuclease 1 (204768_s_at), score: 0.69 FGFR1OPFGFR1 oncogene partner (205588_s_at), score: 0.6 FHL1four and a half LIM domains 1 (201539_s_at), score: -0.68 FHOD3formin homology 2 domain containing 3 (218980_at), score: 0.72 FLJ14213protor-2 (219383_at), score: 0.51 FN3KRPfructosamine 3 kinase related protein (218210_at), score: 0.48 FOLR3folate receptor 3 (gamma) (206371_at), score: 0.61 FOXE1forkhead box E1 (thyroid transcription factor 2) (206912_at), score: -0.54 FOXF2forkhead box F2 (206377_at), score: 0.53 FOXM1forkhead box M1 (202580_x_at), score: 0.5 FOXN3forkhead box N3 (218031_s_at), score: -0.6 FREQfrequenin homolog (Drosophila) (218266_s_at), score: 0.56 FRMD4AFERM domain containing 4A (208476_s_at), score: -0.73 FRMD4BFERM domain containing 4B (213056_at), score: 0.51 FRYfurry homolog (Drosophila) (204072_s_at), score: -0.75 FSTfollistatin (204948_s_at), score: -0.66 FUCA1fucosidase, alpha-L- 1, tissue (202838_at), score: -0.58 FYCO1FYVE and coiled-coil domain containing 1 (218204_s_at), score: -0.74 FZD7frizzled homolog 7 (Drosophila) (203705_s_at), score: -0.58 GABARAPL3GABA(A) receptors associated protein like 3 (pseudogene) (211458_s_at), score: -0.53 GABBR2gamma-aminobutyric acid (GABA) B receptor, 2 (209990_s_at), score: 0.8 GALEUDP-galactose-4-epimerase (202528_at), score: 0.55 GALNAC4S-6STB cell RAG associated protein (203066_at), score: -0.58 GALNT6UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) (219956_at), score: 0.51 GATA2GATA binding protein 2 (209710_at), score: 0.58 GATA6GATA binding protein 6 (210002_at), score: -0.56 GBP2guanylate binding protein 2, interferon-inducible (202748_at), score: -0.63 GDF15growth differentiation factor 15 (221577_x_at), score: -0.65 GINS1GINS complex subunit 1 (Psf1 homolog) (206102_at), score: 0.64 GINS2GINS complex subunit 2 (Psf2 homolog) (221521_s_at), score: 0.61 GINS3GINS complex subunit 3 (Psf3 homolog) (45633_at), score: 0.56 GINS4GINS complex subunit 4 (Sld5 homolog) (211767_at), score: 0.62 GMNNgeminin, DNA replication inhibitor (218350_s_at), score: 0.57 GNPTABN-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (212959_s_at), score: -0.57 GOLGB1golgin B1, golgi integral membrane protein (201057_s_at), score: -0.53 GPC4glypican 4 (204983_s_at), score: 0.51 GPERG protein-coupled estrogen receptor 1 (210640_s_at), score: 0.79 GPR116G protein-coupled receptor 116 (212950_at), score: -0.65 GPR125G protein-coupled receptor 125 (210473_s_at), score: 0.53 GPR89BG protein-coupled receptor 89B (220642_x_at), score: 0.49 GRAMD1CGRAM domain containing 1C (219313_at), score: 0.59 GREM2gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) (220794_at), score: 0.59 GSNgelsolin (amyloidosis, Finnish type) (200696_s_at), score: -0.57 GSTM3glutathione S-transferase mu 3 (brain) (202554_s_at), score: -0.62 GTDC1glycosyltransferase-like domain containing 1 (219770_at), score: -0.66 GTSE1G-2 and S-phase expressed 1 (204318_s_at), score: 0.59 HAS2hyaluronan synthase 2 (206432_at), score: 0.58 HEG1HEG homolog 1 (zebrafish) (213069_at), score: -0.69 HELLShelicase, lymphoid-specific (220085_at), score: 0.51 HERC3hect domain and RLD 3 (206183_s_at), score: 0.54 HIP1huntingtin interacting protein 1 (205425_at), score: 0.71 HIVEP1human immunodeficiency virus type I enhancer binding protein 1 (204512_at), score: -0.77 HJURPHolliday junction recognition protein (218726_at), score: 0.57 HMGA1high mobility group AT-hook 1 (210457_x_at), score: 0.52 HMGB3high-mobility group box 3 (203744_at), score: 0.53 HMMRhyaluronan-mediated motility receptor (RHAMM) (207165_at), score: 0.49 HNMThistamine N-methyltransferase (204112_s_at), score: -0.71 HOXA9homeobox A9 (214651_s_at), score: 0.59 HOXB7homeobox B7 (204779_s_at), score: 0.51 HOXC10homeobox C10 (218959_at), score: 0.56 HOXC11homeobox C11 (206745_at), score: 0.75 HS3ST3A1heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 (219985_at), score: 0.81 HSPA14heat shock 70kDa protein 14 (219212_at), score: 0.52 HTR1F5-hydroxytryptamine (serotonin) receptor 1F (221458_at), score: 0.51 HTRA2HtrA serine peptidase 2 (203089_s_at), score: 0.58 ICAM1intercellular adhesion molecule 1 (202638_s_at), score: -0.58 ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein (208937_s_at), score: 0.51 IER3immediate early response 3 (201631_s_at), score: -0.53 IFI27interferon, alpha-inducible protein 27 (202411_at), score: -0.72 IFT20intraflagellar transport 20 homolog (Chlamydomonas) (210312_s_at), score: -0.68 IL13RA2interleukin 13 receptor, alpha 2 (206172_at), score: 0.48 IL1Ainterleukin 1, alpha (210118_s_at), score: -0.61 IL6interleukin 6 (interferon, beta 2) (205207_at), score: -0.54 ISLRimmunoglobulin superfamily containing leucine-rich repeat (207191_s_at), score: 0.52 ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (205032_at), score: 0.56 ITGA8integrin, alpha 8 (214265_at), score: -0.61 ITGBL1integrin, beta-like 1 (with EGF-like repeat domains) (214927_at), score: -0.55 JAG1jagged 1 (Alagille syndrome) (216268_s_at), score: -0.89 KCND3potassium voltage-gated channel, Shal-related subfamily, member 3 (213832_at), score: -0.79 KCNN4potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (204401_at), score: 0.65 KHSRPKH-type splicing regulatory protein (204372_s_at), score: 0.54 KIAA0182KIAA0182 (212057_at), score: 0.54 KIAA0746KIAA0746 protein (212314_at), score: -0.6 KIAA1199KIAA1199 (212942_s_at), score: -0.66 KIF11kinesin family member 11 (204444_at), score: 0.55 KIF14kinesin family member 14 (206364_at), score: 0.57 KIF15kinesin family member 15 (219306_at), score: 0.63 KIF18Bkinesin family member 18B (222039_at), score: 0.67 KIF20Bkinesin family member 20B (205235_s_at), score: 0.54 KIF22kinesin family member 22 (202183_s_at), score: 0.48 KIF23kinesin family member 23 (204709_s_at), score: 0.49 KIF2Ckinesin family member 2C (209408_at), score: 0.55 KIF4Akinesin family member 4A (218355_at), score: 0.56 KIFC1kinesin family member C1 (209680_s_at), score: 0.54 KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (205051_s_at), score: -0.65 KLF9Kruppel-like factor 9 (203543_s_at), score: -0.75 KNTC1kinetochore associated 1 (206316_s_at), score: 0.59 KRT18keratin 18 (201596_x_at), score: -0.74 LAMA2laminin, alpha 2 (213519_s_at), score: -0.59 LAMA5laminin, alpha 5 (210150_s_at), score: -0.58 LAMC2laminin, gamma 2 (202267_at), score: -0.68 LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein (200923_at), score: -0.79 LIG1ligase I, DNA, ATP-dependent (202726_at), score: 0.67 LIMK1LIM domain kinase 1 (204357_s_at), score: 0.47 LIPGlipase, endothelial (219181_at), score: -0.68 LMBRD1LMBR1 domain containing 1 (218191_s_at), score: -0.55 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: -0.64 LMNB1lamin B1 (203276_at), score: 0.5 LMNB2lamin B2 (216952_s_at), score: 0.49 LMO2LIM domain only 2 (rhombotin-like 1) (204249_s_at), score: -0.59 LOC57228small trans-membrane and glycosylated protein (209679_s_at), score: 0.49 LOC731884similar to programmed cell death 6 interacting protein (217520_x_at), score: 0.62 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: -0.57 LPHN2latrophilin 2 (206953_s_at), score: -0.89 LPPR4plasticity related gene 1 (213496_at), score: -0.8 LPXNleupaxin (216250_s_at), score: 0.76 LRP5low density lipoprotein receptor-related protein 5 (209468_at), score: -0.66 LRRC15leucine rich repeat containing 15 (213909_at), score: 0.83 LRRC17leucine rich repeat containing 17 (205381_at), score: -0.87 LRRC32leucine rich repeat containing 32 (203835_at), score: -0.78 LSM2LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) (209449_at), score: 0.51 LUZP1leucine zipper protein 1 (221832_s_at), score: -0.61 LZTFL1leucine zipper transcription factor-like 1 (218437_s_at), score: -0.61 MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast) (203362_s_at), score: 0.55 MALLmal, T-cell differentiation protein-like (209373_at), score: 0.66 MANSC1MANSC domain containing 1 (220945_x_at), score: -0.6 MAP3K8mitogen-activated protein kinase kinase kinase 8 (205027_s_at), score: -0.79 MARCH2membrane-associated ring finger (C3HC4) 2 (210075_at), score: -0.58 MBPmyelin basic protein (210136_at), score: -0.92 MCM10minichromosome maintenance complex component 10 (220651_s_at), score: 0.75 MCM2minichromosome maintenance complex component 2 (202107_s_at), score: 0.66 MCM3minichromosome maintenance complex component 3 (201555_at), score: 0.67 MCM4minichromosome maintenance complex component 4 (212141_at), score: 0.75 MCM5minichromosome maintenance complex component 5 (216237_s_at), score: 0.63 MCM6minichromosome maintenance complex component 6 (201930_at), score: 0.52 MCM7minichromosome maintenance complex component 7 (210983_s_at), score: 0.6 MDM1Mdm1 nuclear protein homolog (mouse) (213761_at), score: 0.53 MEOX2mesenchyme homeobox 2 (206201_s_at), score: -0.75 MESTmesoderm specific transcript homolog (mouse) (202016_at), score: -0.85 MEX3Dmex-3 homolog D (C. elegans) (91816_f_at), score: 0.76 MGC87042similar to Six transmembrane epithelial antigen of prostate (217553_at), score: 0.59 MGPmatrix Gla protein (202291_s_at), score: -0.89 MKI67antigen identified by monoclonal antibody Ki-67 (212022_s_at), score: 0.59 MLF1IPMLF1 interacting protein (218883_s_at), score: 0.48 MMDmonocyte to macrophage differentiation-associated (203414_at), score: 0.49 MMP14matrix metallopeptidase 14 (membrane-inserted) (202827_s_at), score: 0.54 MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (201069_at), score: 0.57 MMP3matrix metallopeptidase 3 (stromelysin 1, progelatinase) (205828_at), score: 0.67 MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae) (205395_s_at), score: 0.51 MSCmusculin (activated B-cell factor-1) (209928_s_at), score: -0.6 MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (209421_at), score: 0.53 MT1Fmetallothionein 1F (217165_x_at), score: 0.51 MT1Gmetallothionein 1G (204745_x_at), score: 0.49 MT1Hmetallothionein 1H (206461_x_at), score: 0.51 MT1Mmetallothionein 1M (217546_at), score: 0.74 MT1P2metallothionein 1 pseudogene 2 (211456_x_at), score: 0.47 MT1Xmetallothionein 1X (204326_x_at), score: 0.65 MT2Ametallothionein 2A (212185_x_at), score: 0.5 MYBL1v-myb myeloblastosis viral oncogene homolog (avian)-like 1 (213906_at), score: 0.69 MYCT1myc target 1 (220471_s_at), score: -0.65 MYL5myosin, light chain 5, regulatory (205145_s_at), score: -0.53 MYO19myosin XIX (219320_at), score: 0.57 MYO1Emyosin IE (203072_at), score: -0.75 NAP1L4nucleosome assembly protein 1-like 4 (201414_s_at), score: 0.49 NASPnuclear autoantigenic sperm protein (histone-binding) (201970_s_at), score: 0.51 NBL1neuroblastoma, suppression of tumorigenicity 1 (37005_at), score: 0.66 NCAPD3non-SMC condensin II complex, subunit D3 (212789_at), score: 0.58 NCAPGnon-SMC condensin I complex, subunit G (218663_at), score: 0.52 NCAPG2non-SMC condensin II complex, subunit G2 (219588_s_at), score: 0.56 NCAPHnon-SMC condensin I complex, subunit H (212949_at), score: 0.58 NCOA3nuclear receptor coactivator 3 (207700_s_at), score: -0.54 NDUFA4L2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 (218484_at), score: -0.82 NEDD4neural precursor cell expressed, developmentally down-regulated 4 (213012_at), score: 0.55 NEDD9neural precursor cell expressed, developmentally down-regulated 9 (202149_at), score: -0.81 NEK2NIMA (never in mitosis gene a)-related kinase 2 (204641_at), score: 0.48 NET1neuroepithelial cell transforming 1 (201830_s_at), score: 0.68 NID2nidogen 2 (osteonidogen) (204114_at), score: -0.67 NKX3-1NK3 homeobox 1 (209706_at), score: 0.6 NNMTnicotinamide N-methyltransferase (202238_s_at), score: -0.58 NOVnephroblastoma overexpressed gene (214321_at), score: -0.59 NPR3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (219789_at), score: 0.63 NPTX2neuronal pentraxin II (213479_at), score: 0.52 NR1D1nuclear receptor subfamily 1, group D, member 1 (31637_s_at), score: 0.48 NRG1neuregulin 1 (206343_s_at), score: 0.71 NRIP3nuclear receptor interacting protein 3 (219557_s_at), score: 0.79 NRXN3neurexin 3 (205795_at), score: -0.66 NUAK1NUAK family, SNF1-like kinase, 1 (204589_at), score: -0.74 NUP155nucleoporin 155kDa (206550_s_at), score: 0.56 NUP85nucleoporin 85kDa (218014_at), score: 0.57 NUPR1nuclear protein 1 (209230_s_at), score: -0.65 OIP5Opa interacting protein 5 (213599_at), score: 0.53 OLFM1olfactomedin 1 (213131_at), score: 0.74 OPN3opsin 3 (219032_x_at), score: -0.65 OPTNoptineurin (202073_at), score: -0.68 ORAI3ORAI calcium release-activated calcium modulator 3 (221864_at), score: -0.66 ORC1Lorigin recognition complex, subunit 1-like (yeast) (205085_at), score: 0.56 ORC6Lorigin recognition complex, subunit 6 like (yeast) (219105_x_at), score: 0.72 OSBPL10oxysterol binding protein-like 10 (219073_s_at), score: -0.65 OSMRoncostatin M receptor (205729_at), score: -0.57 PAK4p21 protein (Cdc42/Rac)-activated kinase 4 (203154_s_at), score: 0.48 PALMparalemmin (203859_s_at), score: -0.65 PAPPApregnancy-associated plasma protein A, pappalysin 1 (201981_at), score: -0.56 PARP2poly (ADP-ribose) polymerase 2 (214086_s_at), score: 0.51 PCOLCE2procollagen C-endopeptidase enhancer 2 (219295_s_at), score: 0.48 PDCD4programmed cell death 4 (neoplastic transformation inhibitor) (202731_at), score: -0.79 PDE10Aphosphodiesterase 10A (205501_at), score: -0.58 PDE4Bphosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) (203708_at), score: 0.57 PDGFAplatelet-derived growth factor alpha polypeptide (205463_s_at), score: -0.67 PDGFRBplatelet-derived growth factor receptor, beta polypeptide (202273_at), score: -0.88 PDGFRLplatelet-derived growth factor receptor-like (205226_at), score: -0.73 PDSS1prenyl (decaprenyl) diphosphate synthase, subunit 1 (220865_s_at), score: 0.52 PELI1pellino homolog 1 (Drosophila) (218319_at), score: -0.56 PENKproenkephalin (213791_at), score: 0.65 PER3period homolog 3 (Drosophila) (221045_s_at), score: 0.48 PGRMC2progesterone receptor membrane component 2 (213227_at), score: -0.75 PIRpirin (iron-binding nuclear protein) (207469_s_at), score: -0.74 PITPNC1phosphatidylinositol transfer protein, cytoplasmic 1 (219155_at), score: 0.68 PITX2paired-like homeodomain 2 (207558_s_at), score: 0.53 PKIAprotein kinase (cAMP-dependent, catalytic) inhibitor alpha (204612_at), score: 0.73 PKMYT1protein kinase, membrane associated tyrosine/threonine 1 (204267_x_at), score: 0.67 PLA2G16phospholipase A2, group XVI (209581_at), score: -0.88 PLCL1phospholipase C-like 1 (205934_at), score: -0.6 PLEK2pleckstrin 2 (218644_at), score: 0.48 PLK4polo-like kinase 4 (Drosophila) (204887_s_at), score: 0.58 PLSCR4phospholipid scramblase 4 (218901_at), score: -0.79 PLXNC1plexin C1 (213241_at), score: -0.55 PLXND1plexin D1 (38671_at), score: -0.82 PMAIP1phorbol-12-myristate-13-acetate-induced protein 1 (204285_s_at), score: 0.55 PNMA2paraneoplastic antigen MA2 (209598_at), score: -0.86 POLA1polymerase (DNA directed), alpha 1, catalytic subunit (204835_at), score: 0.69 POLA2polymerase (DNA directed), alpha 2 (70kD subunit) (204441_s_at), score: 0.59 POLD1polymerase (DNA directed), delta 1, catalytic subunit 125kDa (203422_at), score: 0.65 POLD3polymerase (DNA-directed), delta 3, accessory subunit (212836_at), score: 0.67 POLEpolymerase (DNA directed), epsilon (216026_s_at), score: 0.56 POLE2polymerase (DNA directed), epsilon 2 (p59 subunit) (205909_at), score: 0.65 POLQpolymerase (DNA directed), theta (219510_at), score: 0.57 POLR3Kpolymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa (218866_s_at), score: 0.48 POSTNperiostin, osteoblast specific factor (210809_s_at), score: -0.79 PPLperiplakin (203407_at), score: -0.57 PPP3CCprotein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (207000_s_at), score: -0.74 PRELPproline/arginine-rich end leucine-rich repeat protein (204223_at), score: -0.58 PRIM1primase, DNA, polypeptide 1 (49kDa) (205053_at), score: 0.67 PRKAG2protein kinase, AMP-activated, gamma 2 non-catalytic subunit (218292_s_at), score: -0.75 PRKG1protein kinase, cGMP-dependent, type I (207119_at), score: -0.63 PROS1protein S (alpha) (207808_s_at), score: -0.57 PRRX2paired related homeobox 2 (219729_at), score: 0.5 PRSS12protease, serine, 12 (neurotrypsin, motopsin) (205515_at), score: -0.61 PSAT1phosphoserine aminotransferase 1 (220892_s_at), score: -0.55 PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) (204279_at), score: -0.54 PSMC3IPPSMC3 interacting protein (213951_s_at), score: 0.67 PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (200830_at), score: 0.51 PSRC1proline/serine-rich coiled-coil 1 (201896_s_at), score: 0.54 PTGER2prostaglandin E receptor 2 (subtype EP2), 53kDa (206631_at), score: 0.63 PTGER4prostaglandin E receptor 4 (subtype EP4) (204897_at), score: -0.75 PTGESprostaglandin E synthase (210367_s_at), score: -0.61 PTGISprostaglandin I2 (prostacyclin) synthase (208131_s_at), score: -0.62 PTGS1prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (215813_s_at), score: 0.6 PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (204469_at), score: -0.61 PTX3pentraxin-related gene, rapidly induced by IL-1 beta (206157_at), score: -0.68 RAB15RAB15, member RAS onocogene family (221810_at), score: 0.75 RAB33BRAB33B, member RAS oncogene family (221014_s_at), score: -0.57 RACGAP1Rac GTPase activating protein 1 (222077_s_at), score: 0.49 RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) (205024_s_at), score: 0.62 RAD51AP1RAD51 associated protein 1 (204146_at), score: 0.51 RAD54BRAD54 homolog B (S. cerevisiae) (219494_at), score: 0.74 RAD54LRAD54-like (S. cerevisiae) (204558_at), score: 0.55 RAD9ARAD9 homolog A (S. pombe) (204828_at), score: 0.49 RANGAP1Ran GTPase activating protein 1 (212125_at), score: 0.55 RAPGEF2Rap guanine nucleotide exchange factor (GEF) 2 (203097_s_at), score: -0.56 RASGRP1RAS guanyl releasing protein 1 (calcium and DAG-regulated) (205590_at), score: -0.56 RBL1retinoblastoma-like 1 (p107) (205296_at), score: 0.71 RCAN3RCAN family member 3 (219864_s_at), score: 0.49 RCN1reticulocalbin 1, EF-hand calcium binding domain (201063_at), score: -0.55 RELNreelin (205923_at), score: -0.67 RFC2replication factor C (activator 1) 2, 40kDa (203696_s_at), score: 0.53 RFC3replication factor C (activator 1) 3, 38kDa (204128_s_at), score: 0.73 RFC4replication factor C (activator 1) 4, 37kDa (204023_at), score: 0.59 RFWD3ring finger and WD repeat domain 3 (218564_at), score: 0.74 RHOBras homolog gene family, member B (212099_at), score: -0.63 RMI1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae) (218979_at), score: 0.62 RNASEH2Aribonuclease H2, subunit A (203022_at), score: 0.63 RNASET2ribonuclease T2 (217983_s_at), score: -0.65 RNF128ring finger protein 128 (219263_at), score: 0.51 ROR1receptor tyrosine kinase-like orphan receptor 1 (205805_s_at), score: -0.76 RORARAR-related orphan receptor A (210426_x_at), score: 0.51 RP11-345P4.4similar to solute carrier family 35, member E2 (217122_s_at), score: -0.53 RRAGBRas-related GTP binding B (205540_s_at), score: -0.66 RRM2ribonucleotide reductase M2 polypeptide (209773_s_at), score: 0.53 RWDD2ARWD domain containing 2A (213555_at), score: -0.6 S100A2S100 calcium binding protein A2 (204268_at), score: 0.64 S1PR1sphingosine-1-phosphate receptor 1 (204642_at), score: 0.6 SC4MOLsterol-C4-methyl oxidase-like (209146_at), score: -0.61 SC5DLsterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like (211423_s_at), score: -0.55 SCARA3scavenger receptor class A, member 3 (219416_at), score: 0.76 SCN9Asodium channel, voltage-gated, type IX, alpha subunit (206950_at), score: -0.65 SCRG1scrapie responsive protein 1 (205475_at), score: -0.58 SDC1syndecan 1 (201287_s_at), score: 0.64 SDC2syndecan 2 (212154_at), score: -0.61 SDPRserum deprivation response (phosphatidylserine binding protein) (218711_s_at), score: -0.6 SECTM1secreted and transmembrane 1 (213716_s_at), score: -0.56 SFRP1secreted frizzled-related protein 1 (202036_s_at), score: 0.68 SHCBP1SHC SH2-domain binding protein 1 (219493_at), score: 0.52 SIX2SIX homeobox 2 (206510_at), score: -0.64 SLC16A2solute carrier family 16, member 2 (monocarboxylic acid transporter 8) (204462_s_at), score: 0.56 SLC19A1solute carrier family 19 (folate transporter), member 1 (211576_s_at), score: 0.49 SLC1A4solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 (209610_s_at), score: -0.62 SLC25A4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 (202825_at), score: -0.55 SLC2A1solute carrier family 2 (facilitated glucose transporter), member 1 (201250_s_at), score: -0.58 SLC2A14solute carrier family 2 (facilitated glucose transporter), member 14 (222088_s_at), score: -0.57 SLC46A3solute carrier family 46, member 3 (214719_at), score: -0.76 SLC7A11solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (217678_at), score: -0.59 SLC7A8solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (216092_s_at), score: 0.71 SLCO3A1solute carrier organic anion transporter family, member 3A1 (219229_at), score: 0.61 SLIT2slit homolog 2 (Drosophila) (209897_s_at), score: 0.51 SMC2structural maintenance of chromosomes 2 (204240_s_at), score: 0.6 SMC4structural maintenance of chromosomes 4 (201663_s_at), score: 0.49 SNTB1syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) (208608_s_at), score: -0.82 SOBPsine oculis binding protein homolog (Drosophila) (218974_at), score: -0.64 SORDsorbitol dehydrogenase (201563_at), score: 0.49 SPAG5sperm associated antigen 5 (203145_at), score: 0.57 SPC25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) (209891_at), score: 0.52 SPINT2serine peptidase inhibitor, Kunitz type, 2 (210715_s_at), score: -0.63 SPOCK1sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 (202363_at), score: -0.57 SPON1spondin 1, extracellular matrix protein (209436_at), score: 0.51 SPSB1splA/ryanodine receptor domain and SOCS box containing 1 (219677_at), score: -0.63 SQLEsqualene epoxidase (213562_s_at), score: -0.59 SQRDLsulfide quinone reductase-like (yeast) (217995_at), score: -0.6 SREBF2sterol regulatory element binding transcription factor 2 (201247_at), score: -0.56 SRGNserglycin (201859_at), score: -0.61 SSX2IPsynovial sarcoma, X breakpoint 2 interacting protein (203016_s_at), score: 0.86 ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4 (203759_at), score: 0.56 STACSH3 and cysteine rich domain (205743_at), score: -0.67 STAT1signal transducer and activator of transcription 1, 91kDa (AFFX-HUMISGF3A/M97935_MA_at), score: -0.66 STAT4signal transducer and activator of transcription 4 (206118_at), score: -0.77 STEAP1six transmembrane epithelial antigen of the prostate 1 (205542_at), score: 0.68 STILSCL/TAL1 interrupting locus (205339_at), score: 0.63 STK38Lserine/threonine kinase 38 like (212572_at), score: -0.7 STMN1stathmin 1/oncoprotein 18 (200783_s_at), score: 0.51 STMN2stathmin-like 2 (203000_at), score: 0.62 SUPT16Hsuppressor of Ty 16 homolog (S. cerevisiae) (217815_at), score: 0.48 SUV39H1suppressor of variegation 3-9 homolog 1 (Drosophila) (218619_s_at), score: 0.59 SUZ12suppressor of zeste 12 homolog (Drosophila) (212287_at), score: 0.49 SYNGR2synaptogyrin 2 (201079_at), score: -0.7 SYNPOsynaptopodin (202796_at), score: -0.62 SYT11synaptotagmin XI (209198_s_at), score: -0.56 TACC3transforming, acidic coiled-coil containing protein 3 (218308_at), score: 0.6 TBC1D1TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 (212350_at), score: 0.5 TBC1D12TBC1 domain family, member 12 (221858_at), score: -0.58 TCF7L1transcription factor 7-like 1 (T-cell specific, HMG-box) (221016_s_at), score: -0.75 TDGthymine-DNA glycosylase (203743_s_at), score: -0.54 TELO2TEL2, telomere maintenance 2, homolog (S. cerevisiae) (34260_at), score: 0.59 TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (204653_at), score: 0.48 TFPItissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (209676_at), score: -0.68 TFPI2tissue factor pathway inhibitor 2 (209278_s_at), score: 0.6 THBS2thrombospondin 2 (203083_at), score: -0.71 TIMELESStimeless homolog (Drosophila) (203046_s_at), score: 0.56 TINAGL1tubulointerstitial nephritis antigen-like 1 (219058_x_at), score: -0.72 TIPINTIMELESS interacting protein (219258_at), score: 0.53 TLR4toll-like receptor 4 (221060_s_at), score: -0.55 TM7SF2transmembrane 7 superfamily member 2 (210130_s_at), score: -0.55 TMEM135transmembrane protein 135 (222209_s_at), score: -0.58 TMEM158transmembrane protein 158 (213338_at), score: 0.77 TMEM194Atransmembrane protein 194A (212621_at), score: 0.73 TMEM38Btransmembrane protein 38B (218772_x_at), score: 0.59 TMPOthymopoietin (209754_s_at), score: 0.56 TMSB15Bthymosin beta 15B (214051_at), score: 0.52 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (210260_s_at), score: -0.56 TNFRSF10Btumor necrosis factor receptor superfamily, member 10b (209295_at), score: -0.81 TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (207426_s_at), score: -0.58 TNS3tensin 3 (217853_at), score: -0.55 TNXAtenascin XA pseudogene (213451_x_at), score: -1 TNXBtenascin XB (216333_x_at), score: -0.98 TOE1target of EGR1, member 1 (nuclear) (204080_at), score: 0.51 TOPBP1topoisomerase (DNA) II binding protein 1 (202633_at), score: 0.57 TP53tumor protein p53 (201746_at), score: -0.56 TPD52L1tumor protein D52-like 1 (203786_s_at), score: -0.62 TPX2TPX2, microtubule-associated, homolog (Xenopus laevis) (210052_s_at), score: 0.5 TRAF5TNF receptor-associated factor 5 (204352_at), score: -0.55 TRAPPC2P1trafficking protein particle complex 2 pseudogene 1 (209751_s_at), score: -0.54 TRAPPC6Atrafficking protein particle complex 6A (204985_s_at), score: -0.64 TRIM22tripartite motif-containing 22 (213293_s_at), score: -0.65 TRIP13thyroid hormone receptor interactor 13 (204033_at), score: 0.6 TRPC6transient receptor potential cation channel, subfamily C, member 6 (217287_s_at), score: -0.59 TRPV2transient receptor potential cation channel, subfamily V, member 2 (219282_s_at), score: -0.62 TSC22D1TSC22 domain family, member 1 (215111_s_at), score: -0.54 TSC22D3TSC22 domain family, member 3 (208763_s_at), score: -0.72 TTC12tetratricopeptide repeat domain 12 (219587_at), score: -0.56 TTC28tetratricopeptide repeat domain 28 (215146_s_at), score: -0.58 TTKTTK protein kinase (204822_at), score: 0.6 TUBGCP5tubulin, gamma complex associated protein 5 (214876_s_at), score: 0.49 TUFT1tuftelin 1 (205807_s_at), score: -0.9 TYRO3TYRO3 protein tyrosine kinase (211432_s_at), score: 0.66 UBA7ubiquitin-like modifier activating enzyme 7 (203281_s_at), score: -0.62 UBE2Cubiquitin-conjugating enzyme E2C (202954_at), score: 0.48 UBR7ubiquitin protein ligase E3 component n-recognin 7 (putative) (218108_at), score: 0.5 UNGuracil-DNA glycosylase (202330_s_at), score: 0.68 USP13ubiquitin specific peptidase 13 (isopeptidase T-3) (205356_at), score: 0.48 USP25ubiquitin specific peptidase 25 (220419_s_at), score: -0.57 VRK1vaccinia related kinase 1 (203856_at), score: 0.61 WDHD1WD repeat and HMG-box DNA binding protein 1 (216228_s_at), score: 0.56 WDR62WD repeat domain 62 (215218_s_at), score: 0.61 WDR76WD repeat domain 76 (205519_at), score: 0.64 WHSC1Wolf-Hirschhorn syndrome candidate 1 (209053_s_at), score: 0.66 WIPI1WD repeat domain, phosphoinositide interacting 1 (203827_at), score: -0.65 WRAP53WD repeat containing, antisense to TP53 (44563_at), score: 0.65 WWP2WW domain containing E3 ubiquitin protein ligase 2 (204022_at), score: -0.67 XBP1X-box binding protein 1 (200670_at), score: -0.58 YPEL5yippee-like 5 (Drosophila) (217783_s_at), score: -0.67 ZNF273zinc finger protein 273 (215239_x_at), score: 0.5 ZNF394zinc finger protein 394 (214714_at), score: -0.64 ZNF395zinc finger protein 395 (218149_s_at), score: 0.48 ZNF423zinc finger protein 423 (214761_at), score: -0.95 ZNF536zinc finger protein 536 (206403_at), score: 0.79 ZNF85zinc finger protein 85 (206572_x_at), score: 0.57 ZWILCHZwilch, kinetochore associated, homolog (Drosophila) (218349_s_at), score: 0.54 ZWINTZW10 interactor (204026_s_at), score: 0.51

Non-Entrez genes

Unknown, score:

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
E-TABM-263-raw-cel-1515486331.cel	35	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486271.cel	32	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486231.cel	30	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515485851.cel	11	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486291.cel	33	6	Cycle	hgu133a2	none	Cycle 1
E-GEOD-3860-raw-cel-1561690336.cel	9	5	HGPS	hgu133a	HGPS	AG10750
E-TABM-263-raw-cel-1515486351.cel	36	6	Cycle	hgu133a2	none	Cycle 1
E-GEOD-3860-raw-cel-1561690304.cel	8	5	HGPS	hgu133a	none	GMO8398C
E-GEOD-3860-raw-cel-1561690256.cel	6	5	HGPS	hgu133a	none	GMO8398C
E-GEOD-3860-raw-cel-1561690392.cel	14	5	HGPS	hgu133a	none	GMO8398C
E-GEOD-3860-raw-cel-1561690223.cel	3	5	HGPS	hgu133a	none	GM00038C
E-GEOD-3860-raw-cel-1561690472.cel	17	5	HGPS	hgu133a	none	GM00038C
E-GEOD-3860-raw-cel-1561690344.cel	10	5	HGPS	hgu133a	none	GM00038C