Previous module | Next module Module #460, TG: 3.2, TC: 1.8, 83 probes, 83 Entrez genes, 8 conditions

Help | Hide | Top Expression data


Expression data for module #460

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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response to mechanical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

response to external stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

response to abiotic stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

all

This term is the most general term possible

response to mechanical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.

Help | Hide | Top The GO tree — Cellular Components

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intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

melanosome

A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

pigment granule

A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04010 3.077e-02 1.974 8
183 MAPK signaling pathway
04810 4.058e-02 1.586 7
147 Regulation of actin cytoskeleton
05222 4.808e-02 0.7876 5
73 Small cell lung cancer

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ADAM15ADAM metallopeptidase domain 15 (217007_s_at), score: 0.73 ADRBK1adrenergic, beta, receptor kinase 1 (201401_s_at), score: 0.69 AP1S1adaptor-related protein complex 1, sigma 1 subunit (205195_at), score: 0.75 ARF1ADP-ribosylation factor 1 (208750_s_at), score: 0.68 ARHGDIARho GDP dissociation inhibitor (GDI) alpha (213606_s_at), score: 0.94 ARPC4actin related protein 2/3 complex, subunit 4, 20kDa (211672_s_at), score: 0.75 ATP13A3ATPase type 13A3 (219558_at), score: 0.73 BCL2L1BCL2-like 1 (215037_s_at), score: 0.82 BSGbasigin (Ok blood group) (208677_s_at), score: 0.69 C19orf22chromosome 19 open reading frame 22 (221764_at), score: 0.68 C19orf6chromosome 19 open reading frame 6 (213986_s_at), score: 1 CD44CD44 molecule (Indian blood group) (210916_s_at), score: 0.87 CDV3CDV3 homolog (mouse) (213548_s_at), score: 0.75 CLIC4chloride intracellular channel 4 (201559_s_at), score: 0.62 CLPTM1cleft lip and palate associated transmembrane protein 1 (211136_s_at), score: 0.7 COL1A1collagen, type I, alpha 1 (217430_x_at), score: 0.66 COL6A1collagen, type VI, alpha 1 (212940_at), score: 0.88 COPAcoatomer protein complex, subunit alpha (214336_s_at), score: 0.82 DAPK3death-associated protein kinase 3 (203890_s_at), score: 0.84 DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (201211_s_at), score: 0.62 DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 9 (212105_s_at), score: 0.65 EIF4G1eukaryotic translation initiation factor 4 gamma, 1 (208624_s_at), score: 0.68 EIF5Aeukaryotic translation initiation factor 5A (201123_s_at), score: 0.75 ELK1ELK1, member of ETS oncogene family (210376_x_at), score: 0.87 EZRezrin (208621_s_at), score: 0.76 FGFR1fibroblast growth factor receptor 1 (210973_s_at), score: 0.87 FN1fibronectin 1 (214701_s_at), score: 0.85 GLULglutamate-ammonia ligase (glutamine synthetase) (200648_s_at), score: 0.64 GPR137G protein-coupled receptor 137 (43934_at), score: 0.62 GPR176G protein-coupled receptor 176 (206673_at), score: 0.67 HMGA1high mobility group AT-hook 1 (210457_x_at), score: 0.79 KCTD20potassium channel tetramerisation domain containing 20 (214849_at), score: 0.71 KDELR1KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (200922_at), score: 0.62 LAMP1lysosomal-associated membrane protein 1 (201551_s_at), score: 0.92 LOC100133105hypothetical protein LOC100133105 (214237_x_at), score: 0.68 LOXlysyl oxidase (213640_s_at), score: 0.63 LOXL2lysyl oxidase-like 2 (202997_s_at), score: 0.86 LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (211019_s_at), score: 0.64 MAFKv-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) (206750_at), score: 0.69 MAP2K2mitogen-activated protein kinase kinase 2 (213490_s_at), score: 0.67 MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2 (201461_s_at), score: 0.65 MAT2Amethionine adenosyltransferase II, alpha (200769_s_at), score: 0.62 MAXMYC associated factor X (210734_x_at), score: 0.88 MAZMYC-associated zinc finger protein (purine-binding transcription factor) (207824_s_at), score: 0.61 MFN2mitofusin 2 (216205_s_at), score: 0.65 MMP14matrix metallopeptidase 14 (membrane-inserted) (202827_s_at), score: 0.86 MPDU1mannose-P-dolichol utilization defect 1 (209208_at), score: 0.65 NAB2NGFI-A binding protein 2 (EGR1 binding protein 2) (216017_s_at), score: 0.7 NUMA1nuclear mitotic apparatus protein 1 (214251_s_at), score: 0.68 PCDHGA11protocadherin gamma subfamily A, 11 (211876_x_at), score: 0.91 PCDHGA3protocadherin gamma subfamily A, 3 (216352_x_at), score: 0.95 PICALMphosphatidylinositol binding clathrin assembly protein (215236_s_at), score: 0.73 PIP5K1Aphosphatidylinositol-4-phosphate 5-kinase, type I, alpha (211205_x_at), score: 0.77 PLEC1plectin 1, intermediate filament binding protein 500kDa (216971_s_at), score: 0.9 POLDIP3polymerase (DNA-directed), delta interacting protein 3 (215357_s_at), score: 0.77 POLR2J2polymerase (RNA) II (DNA directed) polypeptide J2 (216242_x_at), score: 0.64 PPP5Cprotein phosphatase 5, catalytic subunit (201979_s_at), score: 0.64 PRPF6PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) (208879_x_at), score: 0.77 PRRX1paired related homeobox 1 (205991_s_at), score: 0.85 PTBP1polypyrimidine tract binding protein 1 (212016_s_at), score: 0.95 PTMSparathymosin (218045_x_at), score: 0.61 PTP4A1protein tyrosine phosphatase type IVA, member 1 (200730_s_at), score: 0.68 PTPN14protein tyrosine phosphatase, non-receptor type 14 (205503_at), score: 0.8 PXNpaxillin (211823_s_at), score: 0.86 RAB11BRAB11B, member RAS oncogene family (34478_at), score: 0.66 RAB35RAB35, member RAS oncogene family (205461_at), score: 0.83 RAB5ARAB5A, member RAS oncogene family (206113_s_at), score: 0.77 RCAN1regulator of calcineurin 1 (215253_s_at), score: 0.63 RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian) (209878_s_at), score: 0.75 RXRBretinoid X receptor, beta (215099_s_at), score: 0.72 SETD8SET domain containing (lysine methyltransferase) 8 (220200_s_at), score: 0.64 SLC12A4solute carrier family 12 (potassium/chloride transporters), member 4 (209401_s_at), score: 0.7 SLC35E1solute carrier family 35, member E1 (222263_at), score: 0.64 SLC6A9solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (207043_s_at), score: 0.7 SRPRsignal recognition particle receptor (docking protein) (200917_s_at), score: 0.86 STIP1stress-induced-phosphoprotein 1 (212009_s_at), score: 0.78 TGFBR2transforming growth factor, beta receptor II (70/80kDa) (207334_s_at), score: 0.79 TMED2transmembrane emp24 domain trafficking protein 2 (204426_at), score: 0.66 TNFRSF10Dtumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (210654_at), score: 0.67 WACWW domain containing adaptor with coiled-coil (219679_s_at), score: 0.65 WDR1WD repeat domain 1 (210935_s_at), score: 0.7 YIPF5Yip1 domain family, member 5 (221423_s_at), score: 0.65 YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (210317_s_at), score: 0.69

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
46B.CEL 2 3 DS-mosaic hgu133plus2 none DS-mosaic 2
E-TABM-263-raw-cel-1515486031.cel 20 6 Cycle hgu133a2 none Cycle 1
ctrl c 08-03.CEL 3 1 DS-CC hgu133a none DS-CC 3
E-GEOD-3407-raw-cel-1437949655.cel 3 4 Cockayne hgu133a none CSB
4Twin.CEL 4 2 DS-twin hgu133plus2 none DS-twin 4
E-GEOD-3860-raw-cel-1561690199.cel 1 5 HGPS hgu133a none GM0316B
46C.CEL 3 3 DS-mosaic hgu133plus2 none DS-mosaic 3
47B.CEL 4 3 DS-mosaic hgu133plus2 Down mosaic DS-mosaic 4

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