Previous module | Next module Module #563, TG: 3, TC: 2, 59 probes, 59 Entrez genes, 5 conditions

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Expression data for module #563

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

cellular alcohol metabolic process

The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells.

lipid metabolic process

The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

steroid biosynthetic process

The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.

cholesterol biosynthetic process

The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.

isoprenoid metabolic process

The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

cholesterol metabolic process

The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.

isoprenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.

lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

biosynthetic process

The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

sterol metabolic process

The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

sterol biosynthetic process

The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

all

This term is the most general term possible

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

steroid biosynthetic process

The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.

sterol metabolic process

The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

sterol biosynthetic process

The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

isoprenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.

cholesterol biosynthetic process

The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.

Help | Hide | Top The GO tree — Cellular Components

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extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

endomembrane system

A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.

extracellular matrix

A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants).

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
00100 2.717e-07 0.2225 7
23 Biosynthesis of steroids

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide (209612_s_at), score: 0.83 ANK2ankyrin 2, neuronal (202920_at), score: 0.78 B3GALT2UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 (217452_s_at), score: 0.75 C13orf15chromosome 13 open reading frame 15 (218723_s_at), score: 0.85 C4orf18chromosome 4 open reading frame 18 (219872_at), score: 0.72 CCL11chemokine (C-C motif) ligand 11 (210133_at), score: 0.8 COL14A1collagen, type XIV, alpha 1 (212865_s_at), score: 0.73 COL21A1collagen, type XXI, alpha 1 (208096_s_at), score: 0.7 CPA3carboxypeptidase A3 (mast cell) (205624_at), score: 0.76 CSTF2cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa (204459_at), score: -0.68 DAAM2dishevelled associated activator of morphogenesis 2 (212793_at), score: 0.72 DAPK1death-associated protein kinase 1 (203139_at), score: 0.79 DEPDC6DEP domain containing 6 (218858_at), score: 0.71 DHCR77-dehydrocholesterol reductase (201790_s_at), score: 0.71 ECM2extracellular matrix protein 2, female organ and adipocyte specific (206101_at), score: 0.79 ENOX1ecto-NOX disulfide-thiol exchanger 1 (219501_at), score: 0.82 FABP3fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) (214285_at), score: 0.78 FRYfurry homolog (Drosophila) (204072_s_at), score: 0.74 GALNAC4S-6STB cell RAG associated protein (203066_at), score: 0.69 GDPD5glycerophosphodiester phosphodiesterase domain containing 5 (32502_at), score: 0.78 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: 0.7 GTF2A1Lgeneral transcription factor IIA, 1-like (213413_at), score: 0.78 HMGCR3-hydroxy-3-methylglutaryl-Coenzyme A reductase (202539_s_at), score: 0.81 HMGCS13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) (221750_at), score: 0.7 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: 0.79 IFI44Linterferon-induced protein 44-like (204439_at), score: 0.72 IFIH1interferon induced with helicase C domain 1 (219209_at), score: 0.74 INSIG1insulin induced gene 1 (201627_s_at), score: 0.74 KCNB1potassium voltage-gated channel, Shab-related subfamily, member 1 (211006_s_at), score: 0.78 KCND3potassium voltage-gated channel, Shal-related subfamily, member 3 (213832_at), score: 0.8 LDLRlow density lipoprotein receptor (202068_s_at), score: 0.7 LPIN1lipin 1 (212274_at), score: 0.7 LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (211019_s_at), score: 0.83 LZTFL1leucine zipper transcription factor-like 1 (218437_s_at), score: 0.75 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: 0.74 MBPmyelin basic protein (210136_at), score: 0.74 MX2myxovirus (influenza virus) resistance 2 (mouse) (204994_at), score: 0.71 OLFML1olfactomedin-like 1 (217525_at), score: 0.7 OLFML2Aolfactomedin-like 2A (213075_at), score: 0.73 OMDosteomodulin (205907_s_at), score: 0.73 ORAI3ORAI calcium release-activated calcium modulator 3 (221864_at), score: 0.77 PPLperiplakin (203407_at), score: 1 PRELPproline/arginine-rich end leucine-rich repeat protein (204223_at), score: 0.84 PRKG1protein kinase, cGMP-dependent, type I (207119_at), score: 0.83 PRPS2phosphoribosyl pyrophosphate synthetase 2 (203401_at), score: -0.67 RELv-rel reticuloendotheliosis viral oncogene homolog (avian) (206036_s_at), score: 0.76 SC4MOLsterol-C4-methyl oxidase-like (209146_at), score: 0.76 SCDstearoyl-CoA desaturase (delta-9-desaturase) (200832_s_at), score: 0.72 SIX2SIX homeobox 2 (206510_at), score: 0.73 SLC46A3solute carrier family 46, member 3 (214719_at), score: 0.71 SQLEsqualene epoxidase (213562_s_at), score: 0.82 SREBF2sterol regulatory element binding transcription factor 2 (201247_at), score: 0.72 TBC1D12TBC1 domain family, member 12 (221858_at), score: 0.81 TBC1D8TBC1 domain family, member 8 (with GRAM domain) (204526_s_at), score: 0.76 TM7SF2transmembrane 7 superfamily member 2 (210130_s_at), score: 0.7 TNFSF9tumor necrosis factor (ligand) superfamily, member 9 (206907_at), score: 0.83 TNXAtenascin XA pseudogene (213451_x_at), score: 0.77 TNXBtenascin XB (216333_x_at), score: 0.74 XAF1XIAP associated factor 1 (206133_at), score: 0.75

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
ctrl b 08-03.CEL 2 1 DS-CC hgu133a none DS-CC 2
E-TABM-263-raw-cel-1515486231.cel 30 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486331.cel 35 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486271.cel 32 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486291.cel 33 6 Cycle hgu133a2 none Cycle 1

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