Under-expression is coded with green,
over-expression with red color.
cell adhesion
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
anatomical structure morphogenesis
The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
nervous system development
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
biological adhesion
The attachment of a cell or organism to a substrate or other organism.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
all
This term is the most general term possible
cell adhesion
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
anatomical structure morphogenesis
The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
proteinaceous extracellular matrix
A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
extracellular matrix
A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants).
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
structural molecule activity
The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell.
extracellular matrix structural constituent
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
all
This term is the most general term possible
ANK3ankyrin 3, node of Ranvier (ankyrin G) (206385_s_at), score: 0.73 ANKRD1ankyrin repeat domain 1 (cardiac muscle) (206029_at), score: 0.89 ARID5BAT rich interactive domain 5B (MRF1-like) (212614_at), score: 0.66 AUTS2autism susceptibility candidate 2 (212599_at), score: -0.79 B3GALT2UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 (217452_s_at), score: 0.65 BAALCbrain and acute leukemia, cytoplasmic (218899_s_at), score: -0.6 BACE2beta-site APP-cleaving enzyme 2 (217867_x_at), score: -0.68 BST1bone marrow stromal cell antigen 1 (205715_at), score: 0.86 C1orf54chromosome 1 open reading frame 54 (219506_at), score: 0.79 C1QTNF3C1q and tumor necrosis factor related protein 3 (220988_s_at), score: -0.74 C5orf23chromosome 5 open reading frame 23 (219054_at), score: -0.58 C7orf10chromosome 7 open reading frame 10 (219655_at), score: 0.68 C8orf84chromosome 8 open reading frame 84 (214725_at), score: 0.63 CA12carbonic anhydrase XII (203963_at), score: -0.64 CAMK2N1calcium/calmodulin-dependent protein kinase II inhibitor 1 (218309_at), score: -0.96 CAPGcapping protein (actin filament), gelsolin-like (201850_at), score: -0.67 CCDC81coiled-coil domain containing 81 (220389_at), score: 0.7 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: 0.72 CCR10chemokine (C-C motif) receptor 10 (220565_at), score: 0.72 CDH4cadherin 4, type 1, R-cadherin (retinal) (220227_at), score: -0.67 CLGNcalmegin (205830_at), score: -0.65 CNIH3cornichon homolog 3 (Drosophila) (214841_at), score: -0.58 COBLL1COBL-like 1 (203642_s_at), score: 0.69 COL13A1collagen, type XIII, alpha 1 (211343_s_at), score: -0.57 COL4A1collagen, type IV, alpha 1 (211981_at), score: 0.71 COL4A5collagen, type IV, alpha 5 (213110_s_at), score: 0.66 COL8A2collagen, type VIII, alpha 2 (221900_at), score: -0.58 COMPcartilage oligomeric matrix protein (205713_s_at), score: -0.71 CTSCcathepsin C (201487_at), score: 0.77 CYFIP2cytoplasmic FMR1 interacting protein 2 (215785_s_at), score: 0.65 CYP1B1cytochrome P450, family 1, subfamily B, polypeptide 1 (202436_s_at), score: 0.78 DCHS1dachsous 1 (Drosophila) (222101_s_at), score: -0.58 DMDdystrophin (203881_s_at), score: 0.75 DNM1dynamin 1 (215116_s_at), score: -0.66 EDIL3EGF-like repeats and discoidin I-like domains 3 (207379_at), score: 0.78 EIF2S3eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa (205321_at), score: 0.67 EMP2epithelial membrane protein 2 (204975_at), score: -0.58 EMX2empty spiracles homeobox 2 (221950_at), score: -0.7 ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 (205066_s_at), score: -0.81 EPHA5EPH receptor A5 (215664_s_at), score: 0.89 F2Rcoagulation factor II (thrombin) receptor (203989_x_at), score: 0.85 F3coagulation factor III (thromboplastin, tissue factor) (204363_at), score: -0.6 FHL1four and a half LIM domains 1 (201539_s_at), score: 0.67 FHOD3formin homology 2 domain containing 3 (218980_at), score: -0.76 FOLR3folate receptor 3 (gamma) (206371_at), score: -0.57 FOXE1forkhead box E1 (thyroid transcription factor 2) (206912_at), score: 0.69 FRMD4AFERM domain containing 4A (208476_s_at), score: 0.7 FSTfollistatin (204948_s_at), score: 0.79 FYCO1FYVE and coiled-coil domain containing 1 (218204_s_at), score: 0.65 GABBR2gamma-aminobutyric acid (GABA) B receptor, 2 (209990_s_at), score: -0.74 GALNT3UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) (203397_s_at), score: 0.63 GATA6GATA binding protein 6 (210002_at), score: 0.64 GPERG protein-coupled estrogen receptor 1 (210640_s_at), score: -0.7 GPR116G protein-coupled receptor 116 (212950_at), score: 0.9 HAS2hyaluronan synthase 2 (206432_at), score: -0.57 HDAC9histone deacetylase 9 (205659_at), score: 0.64 HIP1huntingtin interacting protein 1 (205425_at), score: -0.59 HMOX1heme oxygenase (decycling) 1 (203665_at), score: -0.78 HNMThistamine N-methyltransferase (204112_s_at), score: 0.63 HOXB7homeobox B7 (204779_s_at), score: -0.68 HOXC11homeobox C11 (206745_at), score: -0.59 HS3ST3A1heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 (219985_at), score: -0.86 IFI27interferon, alpha-inducible protein 27 (202411_at), score: 0.71 IRX5iroquois homeobox 5 (210239_at), score: -0.6 ISLRimmunoglobulin superfamily containing leucine-rich repeat (207191_s_at), score: -0.81 ITGA8integrin, alpha 8 (214265_at), score: 0.65 JAG1jagged 1 (Alagille syndrome) (216268_s_at), score: 0.9 KALRNkalirin, RhoGEF kinase (206078_at), score: 0.72 KCNE4potassium voltage-gated channel, Isk-related family, member 4 (222379_at), score: 0.69 KCNN4potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (204401_at), score: -0.76 KIAA0182KIAA0182 (212057_at), score: -0.65 KIAA1199KIAA1199 (212942_s_at), score: 0.63 KLF9Kruppel-like factor 9 (203543_s_at), score: 0.69 KRT18keratin 18 (201596_x_at), score: 0.8 LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein (200923_at), score: 0.77 LGR5leucine-rich repeat-containing G protein-coupled receptor 5 (213880_at), score: 0.67 LIPGlipase, endothelial (219181_at), score: 0.76 LMO2LIM domain only 2 (rhombotin-like 1) (204249_s_at), score: 0.87 LPHN2latrophilin 2 (206953_s_at), score: 0.89 LPXNleupaxin (216250_s_at), score: -0.74 LRRC15leucine rich repeat containing 15 (213909_at), score: -0.89 LRRC17leucine rich repeat containing 17 (205381_at), score: 0.79 LRRC32leucine rich repeat containing 32 (203835_at), score: 0.66 LRRN3leucine rich repeat neuronal 3 (209841_s_at), score: 0.71 MALLmal, T-cell differentiation protein-like (209373_at), score: -0.59 MAP3K8mitogen-activated protein kinase kinase kinase 8 (205027_s_at), score: 0.63 MBPmyelin basic protein (210136_at), score: 0.84 MEOX2mesenchyme homeobox 2 (206201_s_at), score: 1 MESTmesoderm specific transcript homolog (mouse) (202016_at), score: 0.86 MFAP3Lmicrofibrillar-associated protein 3-like (205442_at), score: 0.65 MGPmatrix Gla protein (202291_s_at), score: 0.9 MMP14matrix metallopeptidase 14 (membrane-inserted) (202827_s_at), score: -0.66 MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (201069_at), score: -0.73 MSX1msh homeobox 1 (205932_s_at), score: -0.76 MT1Mmetallothionein 1M (217546_at), score: -0.76 MYCT1myc target 1 (220471_s_at), score: 0.71 NBL1neuroblastoma, suppression of tumorigenicity 1 (37005_at), score: -0.76 NCAM1neural cell adhesion molecule 1 (212843_at), score: -0.65 NDNnecdin homolog (mouse) (209550_at), score: -0.65 NDUFA4L2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 (218484_at), score: 0.96 NEDD9neural precursor cell expressed, developmentally down-regulated 9 (202149_at), score: 0.63 NEFMneurofilament, medium polypeptide (205113_at), score: 0.66 NET1neuroepithelial cell transforming 1 (201830_s_at), score: -0.79 NFASCneurofascin homolog (chicken) (213438_at), score: -0.6 NID2nidogen 2 (osteonidogen) (204114_at), score: 0.74 NKX3-1NK3 homeobox 1 (209706_at), score: -0.81 NMNAT2nicotinamide nucleotide adenylyltransferase 2 (209755_at), score: 0.64 NOVnephroblastoma overexpressed gene (214321_at), score: 0.76 NRG1neuregulin 1 (206343_s_at), score: -0.72 NRIP3nuclear receptor interacting protein 3 (219557_s_at), score: -0.59 NRXN3neurexin 3 (205795_at), score: 0.76 OLFM1olfactomedin 1 (213131_at), score: -0.67 OLFML3olfactomedin-like 3 (218162_at), score: -0.68 PBX1pre-B-cell leukemia homeobox 1 (212148_at), score: -0.68 PDE10Aphosphodiesterase 10A (205501_at), score: 0.8 PDE4Bphosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) (203708_at), score: -0.59 PLA2G16phospholipase A2, group XVI (209581_at), score: 0.79 PLXND1plexin D1 (38671_at), score: 0.74 PNMA2paraneoplastic antigen MA2 (209598_at), score: 0.84 POSTNperiostin, osteoblast specific factor (210809_s_at), score: 0.74 PRKAG2protein kinase, AMP-activated, gamma 2 non-catalytic subunit (218292_s_at), score: 0.74 PSG5pregnancy specific beta-1-glycoprotein 5 (204830_x_at), score: -0.61 PSG9pregnancy specific beta-1-glycoprotein 9 (209594_x_at), score: -0.57 PTGER2prostaglandin E receptor 2 (subtype EP2), 53kDa (206631_at), score: -0.57 PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (204469_at), score: 0.84 PTX3pentraxin-related gene, rapidly induced by IL-1 beta (206157_at), score: 0.7 QSOX1quiescin Q6 sulfhydryl oxidase 1 (201482_at), score: 0.64 RAB15RAB15, member RAS onocogene family (221810_at), score: -0.68 RELNreelin (205923_at), score: 0.85 RGS7regulator of G-protein signaling 7 (206290_s_at), score: 0.78 RNF128ring finger protein 128 (219263_at), score: -0.6 RORARAR-related orphan receptor A (210426_x_at), score: -0.65 RTN1reticulon 1 (203485_at), score: 0.66 SCN9Asodium channel, voltage-gated, type IX, alpha subunit (206950_at), score: 0.67 SCRG1scrapie responsive protein 1 (205475_at), score: 0.64 SDC1syndecan 1 (201287_s_at), score: -0.59 SDPRserum deprivation response (phosphatidylserine binding protein) (218711_s_at), score: 0.65 SEPT6septin 6 (212414_s_at), score: -0.61 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: 0.65 SETBP1SET binding protein 1 (205933_at), score: -0.69 SFRP1secreted frizzled-related protein 1 (202036_s_at), score: -0.68 SGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein) (213543_at), score: -0.74 SLC24A3solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 (57588_at), score: 0.73 SLC25A4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 (202825_at), score: 0.78 SLC7A1solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 (212295_s_at), score: -0.59 SLC7A11solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (217678_at), score: 0.68 SLC7A8solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (216092_s_at), score: -0.85 SLCO3A1solute carrier organic anion transporter family, member 3A1 (219229_at), score: -0.71 SNAI1snail homolog 1 (Drosophila) (219480_at), score: -0.59 SNTB1syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) (208608_s_at), score: 0.68 SOBPsine oculis binding protein homolog (Drosophila) (218974_at), score: 0.69 SRGNserglycin (201859_at), score: 0.79 SSX2IPsynovial sarcoma, X breakpoint 2 interacting protein (203016_s_at), score: -0.69 STAT1signal transducer and activator of transcription 1, 91kDa (AFFX-HUMISGF3A/M97935_MA_at), score: 0.7 STAT4signal transducer and activator of transcription 4 (206118_at), score: 0.68 STEAP1six transmembrane epithelial antigen of the prostate 1 (205542_at), score: -0.61 STMN2stathmin-like 2 (203000_at), score: -0.77 SUSD5sushi domain containing 5 (214954_at), score: 0.7 SYNGR2synaptogyrin 2 (201079_at), score: 0.67 TCF7L1transcription factor 7-like 1 (T-cell specific, HMG-box) (221016_s_at), score: 0.7 TFPItissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (209676_at), score: 0.7 TINAGL1tubulointerstitial nephritis antigen-like 1 (219058_x_at), score: 0.84 TLR4toll-like receptor 4 (221060_s_at), score: 0.66 TMEM158transmembrane protein 158 (213338_at), score: -0.9 TNXAtenascin XA pseudogene (213451_x_at), score: 0.86 TNXBtenascin XB (216333_x_at), score: 0.85 TRPV2transient receptor potential cation channel, subfamily V, member 2 (219282_s_at), score: 0.68 TUFT1tuftelin 1 (205807_s_at), score: 0.78 UBL3ubiquitin-like 3 (201535_at), score: -0.64 WWP2WW domain containing E3 ubiquitin protein ligase 2 (204022_at), score: 0.73 ZCCHC14zinc finger, CCHC domain containing 14 (212655_at), score: -0.61 ZNF423zinc finger protein 423 (214761_at), score: 0.94 ZNF536zinc finger protein 536 (206403_at), score: -0.76
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-GEOD-3860-raw-cel-1561690256.cel | 6 | 5 | HGPS | hgu133a | none | GMO8398C |
| E-GEOD-3860-raw-cel-1561690223.cel | 3 | 5 | HGPS | hgu133a | none | GM00038C |
| E-GEOD-3860-raw-cel-1561690392.cel | 14 | 5 | HGPS | hgu133a | none | GMO8398C |
| E-GEOD-3860-raw-cel-1561690344.cel | 10 | 5 | HGPS | hgu133a | none | GM00038C |
| E-GEOD-3860-raw-cel-1561690472.cel | 17 | 5 | HGPS | hgu133a | none | GM00038C |
| E-GEOD-3860-raw-cel-1561690360.cel | 12 | 5 | HGPS | hgu133a | none | GM0316B |
| E-GEOD-3860-raw-cel-1561690304.cel | 8 | 5 | HGPS | hgu133a | none | GMO8398C |
| E-GEOD-3860-raw-cel-1561690416.cel | 15 | 5 | HGPS | hgu133a | none | GM0316B |
| E-GEOD-3860-raw-cel-1561690248.cel | 5 | 5 | HGPS | hgu133a | HGPS | AG11513 |
| E-GEOD-3860-raw-cel-1561690336.cel | 9 | 5 | HGPS | hgu133a | HGPS | AG10750 |
