Previous module | Next module Module #666, TG: 2.8, TC: 2, 185 probes, 185 Entrez genes, 3 conditions

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Expression data for module #666

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

biological adhesion

The attachment of a cell or organism to a substrate or other organism.

all

This term is the most general term possible

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
05220 2.237e-02 1.786 8
64 Chronic myeloid leukemia
05222 4.318e-02 2.037 8
73 Small cell lung cancer

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

A2Malpha-2-macroglobulin (217757_at), score: 0.55 ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif, 12 (221421_s_at), score: -0.85 ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif, 2 (214454_at), score: -0.53 ADAP2ArfGAP with dual PH domains 2 (219358_s_at), score: 0.55 ANGPTL2angiopoietin-like 2 (213004_at), score: 0.56 APOL1apolipoprotein L, 1 (209546_s_at), score: 0.57 APOL6apolipoprotein L, 6 (219716_at), score: 0.61 ARFRP1ADP-ribosylation factor related protein 1 (215984_s_at), score: -0.51 ARHGDIARho GDP dissociation inhibitor (GDI) alpha (213606_s_at), score: -0.64 ARPC4actin related protein 2/3 complex, subunit 4, 20kDa (211672_s_at), score: -0.59 B9D1B9 protein domain 1 (210534_s_at), score: 0.68 BACE2beta-site APP-cleaving enzyme 2 (217867_x_at), score: -0.5 BAT2D1BAT2 domain containing 1 (211947_s_at), score: -0.62 BCHEbutyrylcholinesterase (205433_at), score: -0.9 BCL2L1BCL2-like 1 (215037_s_at), score: -0.57 BDKRB1bradykinin receptor B1 (207510_at), score: 0.54 BET1Lblocked early in transport 1 homolog (S. cerevisiae)-like (220470_at), score: -0.61 BRD2bromodomain containing 2 (214911_s_at), score: -0.53 BTRCbeta-transducin repeat containing (216091_s_at), score: -0.56 C11orf41chromosome 11 open reading frame 41 (214772_at), score: -0.6 C21orf7chromosome 21 open reading frame 7 (221211_s_at), score: -0.7 CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (211368_s_at), score: 0.72 CCND1cyclin D1 (208711_s_at), score: -0.6 CD82CD82 molecule (203904_x_at), score: -0.52 CDK10cyclin-dependent kinase 10 (210622_x_at), score: -0.52 CDK6cyclin-dependent kinase 6 (207143_at), score: -0.5 CFIcomplement factor I (203854_at), score: 0.99 CLTCL1clathrin, heavy chain-like 1 (205944_s_at), score: 0.59 CMAHcytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) pseudogene (205518_s_at), score: -0.66 COL1A1collagen, type I, alpha 1 (217430_x_at), score: -0.6 COPAcoatomer protein complex, subunit alpha (214336_s_at), score: -0.56 CYTH3cytohesin 3 (206523_at), score: -0.62 CYTIPcytohesin 1 interacting protein (209606_at), score: -1 DAPK3death-associated protein kinase 3 (203890_s_at), score: -0.56 DDX24DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 (200702_s_at), score: -0.53 DENND3DENN/MADD domain containing 3 (212974_at), score: -0.51 DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 9 (212105_s_at), score: -0.59 DKFZp434H1419hypothetical protein DKFZp434H1419 (214717_at), score: -0.55 DKK1dickkopf homolog 1 (Xenopus laevis) (204602_at), score: -0.52 DOM3Zdom-3 homolog Z (C. elegans) (215982_s_at), score: 0.55 DOPEY2dopey family member 2 (205248_at), score: -0.53 DSC2desmocollin 2 (204751_x_at), score: -0.76 DSC3desmocollin 3 (206032_at), score: -0.61 ECHDC2enoyl Coenzyme A hydratase domain containing 2 (218552_at), score: 0.71 EDN1endothelin 1 (218995_s_at), score: -0.62 EFHC1EF-hand domain (C-terminal) containing 1 (219833_s_at), score: 0.55 EGFepidermal growth factor (beta-urogastrone) (206254_at), score: 0.83 EIF2S1eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (201143_s_at), score: -0.57 EIF4G1eukaryotic translation initiation factor 4 gamma, 1 (208624_s_at), score: -0.52 EIF5Aeukaryotic translation initiation factor 5A (201123_s_at), score: -0.52 ELK1ELK1, member of ETS oncogene family (210376_x_at), score: -0.59 ELOVL2elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 (213712_at), score: 0.85 ERN1endoplasmic reticulum to nucleus signaling 1 (207061_at), score: -0.53 EZRezrin (208621_s_at), score: -0.55 FAM155Afamily with sequence similarity 155, member A (214825_at), score: -0.56 FEZ1fasciculation and elongation protein zeta 1 (zygin I) (203562_at), score: 0.61 FGFR1fibroblast growth factor receptor 1 (210973_s_at), score: -0.52 FGFR3fibroblast growth factor receptor 3 (204379_s_at), score: 0.6 FKRPfukutin related protein (219853_at), score: -0.51 FN1fibronectin 1 (214701_s_at), score: -0.69 FOSv-fos FBJ murine osteosarcoma viral oncogene homolog (209189_at), score: 0.76 GBP2guanylate binding protein 2, interferon-inducible (202748_at), score: 0.55 GCH1GTP cyclohydrolase 1 (204224_s_at), score: 0.78 GGT1gamma-glutamyltransferase 1 (209919_x_at), score: 0.69 GPC4glypican 4 (204983_s_at), score: 0.88 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: 0.6 GPR56G protein-coupled receptor 56 (212070_at), score: 0.59 GPX3glutathione peroxidase 3 (plasma) (214091_s_at), score: -0.64 HAPLN1hyaluronan and proteoglycan link protein 1 (205523_at), score: -0.75 HEY1hairy/enhancer-of-split related with YRPW motif 1 (44783_s_at), score: 0.58 HHEXhematopoietically expressed homeobox (215933_s_at), score: 0.68 HIST2H2AA3histone cluster 2, H2aa3 (214290_s_at), score: -0.5 HMOX1heme oxygenase (decycling) 1 (203665_at), score: 0.58 HOXB9homeobox B9 (216417_x_at), score: -0.99 HPS1Hermansky-Pudlak syndrome 1 (217354_s_at), score: -0.52 IL15RAinterleukin 15 receptor, alpha (207375_s_at), score: 0.55 IL1R1interleukin 1 receptor, type I (202948_at), score: 0.57 IL21Rinterleukin 21 receptor (219971_at), score: -0.52 INHBEinhibin, beta E (210587_at), score: 0.91 JAM3junctional adhesion molecule 3 (212813_at), score: -0.5 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (221778_at), score: 0.59 KCNN2potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 (220116_at), score: -0.67 KCTD20potassium channel tetramerisation domain containing 20 (214849_at), score: -0.61 KIAA0644KIAA0644 gene product (205150_s_at), score: 0.56 L1CAML1 cell adhesion molecule (204584_at), score: 0.57 LAMP1lysosomal-associated membrane protein 1 (201551_s_at), score: -0.58 LATS1LATS, large tumor suppressor, homolog 1 (Drosophila) (219813_at), score: -0.57 LHPPphospholysine phosphohistidine inorganic pyrophosphate phosphatase (218523_at), score: 0.69 LOC100128414similar to fibrinogen silencer binding protein (220549_at), score: -0.5 LOC730092RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene (216908_x_at), score: -0.56 LOXL2lysyl oxidase-like 2 (202997_s_at), score: -0.61 LRRN3leucine rich repeat neuronal 3 (209841_s_at), score: -0.6 LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (211019_s_at), score: -0.55 MACROD1MACRO domain containing 1 (219188_s_at), score: 0.67 MALLmal, T-cell differentiation protein-like (209373_at), score: 0.62 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: 0.56 MAP2K2mitogen-activated protein kinase kinase 2 (213490_s_at), score: -0.5 MAPRE3microtubule-associated protein, RP/EB family, member 3 (214270_s_at), score: -0.52 MAXMYC associated factor X (210734_x_at), score: -0.6 MAZMYC-associated zinc finger protein (purine-binding transcription factor) (207824_s_at), score: -0.64 MCAMmelanoma cell adhesion molecule (210869_s_at), score: -0.51 ME3malic enzyme 3, NADP(+)-dependent, mitochondrial (204663_at), score: 0.66 MED31mediator complex subunit 31 (219318_x_at), score: -0.6 MEGF8multiple EGF-like-domains 8 (214778_at), score: -0.54 MEGF9multiple EGF-like-domains 9 (212830_at), score: 0.58 MFAP2microfibrillar-associated protein 2 (203417_at), score: -0.51 MFAP4microfibrillar-associated protein 4 (212713_at), score: 0.6 MFN2mitofusin 2 (216205_s_at), score: -0.67 MFSD6major facilitator superfamily domain containing 6 (219858_s_at), score: 0.7 MMP14matrix metallopeptidase 14 (membrane-inserted) (202827_s_at), score: -0.59 MOCOSmolybdenum cofactor sulfurase (219959_at), score: 0.64 MRASmuscle RAS oncogene homolog (206538_at), score: -0.53 MRPS18Amitochondrial ribosomal protein S18A (221693_s_at), score: -0.52 MRPS6mitochondrial ribosomal protein S6 (213167_s_at), score: -0.73 NAB2NGFI-A binding protein 2 (EGR1 binding protein 2) (216017_s_at), score: -0.56 NCAM2neural cell adhesion molecule 2 (205669_at), score: 0.57 NFATC4nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (205897_at), score: -0.53 NPTX1neuronal pentraxin I (204684_at), score: -0.52 NR1H3nuclear receptor subfamily 1, group H, member 3 (203920_at), score: 0.62 NUMA1nuclear mitotic apparatus protein 1 (214251_s_at), score: -0.61 OLFML2Aolfactomedin-like 2A (213075_at), score: 0.58 OLR1oxidized low density lipoprotein (lectin-like) receptor 1 (210004_at), score: -0.67 OR2A9Polfactory receptor, family 2, subfamily A, member 9 pseudogene (222290_at), score: 0.55 PACS1phosphofurin acidic cluster sorting protein 1 (220557_s_at), score: -0.62 PAPPA2pappalysin 2 (213332_at), score: 0.8 PCDHGA11protocadherin gamma subfamily A, 11 (211876_x_at), score: -0.51 PCDHGA3protocadherin gamma subfamily A, 3 (216352_x_at), score: -0.54 PDE1Cphosphodiesterase 1C, calmodulin-dependent 70kDa (207303_at), score: -0.76 PIONpigeon homolog (Drosophila) (222150_s_at), score: 0.58 PIP5K1Aphosphatidylinositol-4-phosphate 5-kinase, type I, alpha (211205_x_at), score: -0.5 POLDIP3polymerase (DNA-directed), delta interacting protein 3 (215357_s_at), score: -0.51 POMT1protein-O-mannosyltransferase 1 (218476_at), score: 0.63 PPP2R5Dprotein phosphatase 2, regulatory subunit B', delta isoform (211159_s_at), score: -0.62 PRPF6PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) (208879_x_at), score: -0.52 PSG9pregnancy specific beta-1-glycoprotein 9 (209594_x_at), score: -0.51 PSME4proteasome (prosome, macropain) activator subunit 4 (212220_at), score: -0.53 PTBP1polypyrimidine tract binding protein 1 (212016_s_at), score: -0.58 PTGDSprostaglandin D2 synthase 21kDa (brain) (212187_x_at), score: 0.72 PTGER4prostaglandin E receptor 4 (subtype EP4) (204897_at), score: 0.58 PTMSparathymosin (218045_x_at), score: -0.57 PTPRAprotein tyrosine phosphatase, receptor type, A (213799_s_at), score: -0.69 PTPREprotein tyrosine phosphatase, receptor type, E (221840_at), score: 0.71 PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (204469_at), score: -0.53 PTRFpolymerase I and transcript release factor (208790_s_at), score: -0.62 PXNpaxillin (211823_s_at), score: -0.63 RARRES3retinoic acid receptor responder (tazarotene induced) 3 (204070_at), score: 0.95 RASA3RAS p21 protein activator 3 (206220_s_at), score: -0.64 RASA4RAS p21 protein activator 4 (208534_s_at), score: -0.58 RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian) (209878_s_at), score: -0.65 RXRBretinoid X receptor, beta (215099_s_at), score: -0.57 SEC14L1SEC14-like 1 (S. cerevisiae) (202082_s_at), score: -0.64 SERPINB9serpin peptidase inhibitor, clade B (ovalbumin), member 9 (209723_at), score: 0.55 SERPINI1serpin peptidase inhibitor, clade I (neuroserpin), member 1 (205352_at), score: -0.6 SHC1SHC (Src homology 2 domain containing) transforming protein 1 (201469_s_at), score: -0.51 SIM2single-minded homolog 2 (Drosophila) (206558_at), score: -0.58 SKIv-ski sarcoma viral oncogene homolog (avian) (204270_at), score: -0.5 SLC26A6solute carrier family 26, member 6 (221572_s_at), score: 0.8 SLC29A1solute carrier family 29 (nucleoside transporters), member 1 (201801_s_at), score: -0.72 SLC6A6solute carrier family 6 (neurotransmitter transporter, taurine), member 6 (205921_s_at), score: -0.52 SLC6A9solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (207043_s_at), score: -0.54 SNCAsynuclein, alpha (non A4 component of amyloid precursor) (204466_s_at), score: -0.7 SONSON DNA binding protein (201085_s_at), score: -0.52 SPPL2Bsignal peptide peptidase-like 2B (215833_s_at), score: -0.67 STAT2signal transducer and activator of transcription 2, 113kDa (205170_at), score: -0.91 STK32Bserine/threonine kinase 32B (219686_at), score: -0.5 SULT1A2sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (207122_x_at), score: 0.65 SULT1A3sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (210580_x_at), score: 0.67 SYT1synaptotagmin I (203999_at), score: 0.59 TANC2tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 (208425_s_at), score: -0.8 TAPBPLTAP binding protein-like (218747_s_at), score: 0.55 TEKTEK tyrosine kinase, endothelial (206702_at), score: -0.55 TGFBR1transforming growth factor, beta receptor 1 (206943_at), score: -0.64 TGFBR2transforming growth factor, beta receptor II (70/80kDa) (207334_s_at), score: -0.51 TLE1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (203221_at), score: 0.55 TLR3toll-like receptor 3 (206271_at), score: 0.62 TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (209354_at), score: 0.62 TOM1target of myb1 (chicken) (202807_s_at), score: 0.56 TOM1L2target of myb1-like 2 (chicken) (214840_at), score: -0.82 TOP3Atopoisomerase (DNA) III alpha (214300_s_at), score: -0.62 TRAF1TNF receptor-associated factor 1 (205599_at), score: -0.63 ZFP36L2zinc finger protein 36, C3H type-like 2 (201367_s_at), score: -0.58 ZFPL1zinc finger protein-like 1 (209428_s_at), score: -0.56 ZNF467zinc finger protein 467 (214746_s_at), score: 0.66 ZNF688zinc finger protein 688 (213527_s_at), score: 0.65 ZNF711zinc finger protein 711 (207781_s_at), score: 0.56

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
47C.CEL 5 3 DS-mosaic hgu133plus2 Down mosaic DS-mosaic 5
47B.CEL 4 3 DS-mosaic hgu133plus2 Down mosaic DS-mosaic 4
46B.CEL 2 3 DS-mosaic hgu133plus2 none DS-mosaic 2

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