Under-expression is coded with green,
over-expression with red color.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
anatomical structure morphogenesis
The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
nervous system development
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
salivary gland development
The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.
salivary gland morphogenesis
The process by which the anatomical structures of the salivary gland are generated and organized. Morphogenesis pertains to the creation of form.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
gland morphogenesis
The process by which the anatomical structures of a gland are generated and organized. Morphogenesis pertains to the creation of form.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
exocrine system development
Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
gland development
The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
all
This term is the most general term possible
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
anatomical structure morphogenesis
The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
salivary gland development
The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.
gland morphogenesis
The process by which the anatomical structures of a gland are generated and organized. Morphogenesis pertains to the creation of form.
salivary gland morphogenesis
The process by which the anatomical structures of the salivary gland are generated and organized. Morphogenesis pertains to the creation of form.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
aldo-keto reductase activity
Catalysis of the NADPH-dependent reduction of carbonyl compounds.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
steroid dehydrogenase activity
Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.
oxidoreductase activity, acting on CH-OH group of donors
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
oxidoreductase activity, acting on the CH-CH group of donors
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
3-alpha-hydroxysteroid dehydrogenase (A-specific) activity
Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol.
all
This term is the most general term possible
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
ACSL5acyl-CoA synthetase long-chain family member 5 (218322_s_at), score: -0.68 AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase) (206561_s_at), score: -0.9 AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) (209699_x_at), score: -0.63 AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (209160_at), score: -0.65 ALDH3A1aldehyde dehydrogenase 3 family, memberA1 (205623_at), score: -0.69 BMP7bone morphogenetic protein 7 (209590_at), score: -0.74 C14orf169chromosome 14 open reading frame 169 (219526_at), score: 0.71 C20orf39chromosome 20 open reading frame 39 (219310_at), score: -0.81 CELSR1cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) (41660_at), score: -0.86 CELSR3cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) (40020_at), score: -0.71 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: -0.63 DLX4distal-less homeobox 4 (208216_at), score: -0.67 EGLN3egl nine homolog 3 (C. elegans) (219232_s_at), score: -0.68 FAM174Bfamily with sequence similarity 174, member B (51158_at), score: 0.76 FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32) (203561_at), score: -0.81 FGF13fibroblast growth factor 13 (205110_s_at), score: -0.64 GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 2 (207014_at), score: -0.76 GREM1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) (218469_at), score: 0.99 HEY1hairy/enhancer-of-split related with YRPW motif 1 (44783_s_at), score: -0.63 HLA-DRB1major histocompatibility complex, class II, DR beta 1 (209312_x_at), score: -0.68 IGSF3immunoglobulin superfamily, member 3 (202421_at), score: -0.85 KYNUkynureninase (L-kynurenine hydrolase) (217388_s_at), score: -1 LEF1lymphoid enhancer-binding factor 1 (221558_s_at), score: -0.84 LUMlumican (201744_s_at), score: 0.73 MPPED2metallophosphoesterase domain containing 2 (205413_at), score: -1 MYO1Bmyosin IB (212364_at), score: 0.75 NDRG1N-myc downstream regulated 1 (200632_s_at), score: -0.68 NPTX1neuronal pentraxin I (204684_at), score: -0.67 RARBretinoic acid receptor, beta (205080_at), score: -0.69 RBM47RNA binding motif protein 47 (218035_s_at), score: -0.66 RIPK4receptor-interacting serine-threonine kinase 4 (221215_s_at), score: -0.67 SPANXCSPANX family, member C (220217_x_at), score: -0.65 SULT1A1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (203615_x_at), score: -0.66 TGFB2transforming growth factor, beta 2 (220407_s_at), score: -0.69 VAV3vav 3 guanine nucleotide exchange factor (218807_at), score: -0.74 VCAM1vascular cell adhesion molecule 1 (203868_s_at), score: -0.63
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-GEOD-4219-raw-cel-1311956457.cel | 14 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956138.cel | 4 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956614.cel | 18 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956321.cel | 9 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956824.cel | 24 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956358.cel | 10 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956178.cel | 6 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
