Under-expression is coded with green,
over-expression with red color.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
nervous system development
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
neurogenesis
Generation of cells within the nervous system.
cell differentiation
The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
neuron differentiation
The process whereby a relatively unspecialized cell acquires specialized features of a neuron.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
regulation of cell differentiation
Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.
negative regulation of cell differentiation
Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation.
regulation of neuron differentiation
Any process that modulates the frequency, rate or extent of neuron differentiation.
negative regulation of neuron differentiation
Any process that stops, prevents or reduces the frequency, rate or extent of neuron differentiation.
cell development
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
negative regulation of biological process
Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
negative regulation of cellular process
Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
generation of neurons
The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
regulation of neurogenesis
Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of developmental process
Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
negative regulation of developmental process
Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
regulation of nervous system development
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
regulation of cell development
Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
all
This term is the most general term possible
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
negative regulation of cellular process
Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
negative regulation of developmental process
Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
negative regulation of biological process
Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of developmental process
Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
negative regulation of cellular process
Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
regulation of cell differentiation
Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.
negative regulation of developmental process
Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
regulation of nervous system development
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
negative regulation of cell differentiation
Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation.
regulation of neurogenesis
Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
regulation of cell differentiation
Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.
negative regulation of cell differentiation
Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation.
cell development
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
negative regulation of cell differentiation
Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation.
regulation of cell development
Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
regulation of neurogenesis
Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
neuron differentiation
The process whereby a relatively unspecialized cell acquires specialized features of a neuron.
regulation of neurogenesis
Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
regulation of neuron differentiation
Any process that modulates the frequency, rate or extent of neuron differentiation.
negative regulation of neuron differentiation
Any process that stops, prevents or reduces the frequency, rate or extent of neuron differentiation.
neurogenesis
Generation of cells within the nervous system.
regulation of nervous system development
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
negative regulation of neuron differentiation
Any process that stops, prevents or reduces the frequency, rate or extent of neuron differentiation.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
extracellular space
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
ADAM23ADAM metallopeptidase domain 23 (206046_at), score: 0.87 APOL1apolipoprotein L, 1 (209546_s_at), score: 0.66 ARID5AAT rich interactive domain 5A (MRF1-like) (213138_at), score: 0.68 ARL4CADP-ribosylation factor-like 4C (202207_at), score: 0.7 BCAMbasal cell adhesion molecule (Lutheran blood group) (40093_at), score: 0.58 C16orf45chromosome 16 open reading frame 45 (212736_at), score: 0.61 C19orf28chromosome 19 open reading frame 28 (220178_at), score: 0.6 CA11carbonic anhydrase XI (209726_at), score: 0.62 CDH13cadherin 13, H-cadherin (heart) (204726_at), score: 0.72 COL4A5collagen, type IV, alpha 5 (213110_s_at), score: 0.73 CORINcorin, serine peptidase (220356_at), score: 0.61 CUX1cut-like homeobox 1 (214743_at), score: 0.59 CYFIP2cytoplasmic FMR1 interacting protein 2 (215785_s_at), score: 0.73 DAAM2dishevelled associated activator of morphogenesis 2 (212793_at), score: 0.76 DNAJB5DnaJ (Hsp40) homolog, subfamily B, member 5 (212817_at), score: 0.69 DUSP3dual specificity phosphatase 3 (201536_at), score: 0.6 EFHD1EF-hand domain family, member D1 (209343_at), score: 0.91 ERAP1endoplasmic reticulum aminopeptidase 1 (214012_at), score: 0.7 EREGepiregulin (205767_at), score: 0.59 FHOD1formin homology 2 domain containing 1 (218530_at), score: 0.77 GALNT3UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) (203397_s_at), score: 0.91 GEMGTP binding protein overexpressed in skeletal muscle (204472_at), score: 0.61 GPX3glutathione peroxidase 3 (plasma) (214091_s_at), score: 0.83 HES1hairy and enhancer of split 1, (Drosophila) (203394_s_at), score: 0.68 HLA-Amajor histocompatibility complex, class I, A (217436_x_at), score: 0.61 HLA-Cmajor histocompatibility complex, class I, C (211799_x_at), score: 0.65 HNMThistamine N-methyltransferase (204112_s_at), score: 0.75 IL23Ainterleukin 23, alpha subunit p19 (211796_s_at), score: 0.65 LAMA5laminin, alpha 5 (210150_s_at), score: 0.62 LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein (200923_at), score: 0.6 LIMS2LIM and senescent cell antigen-like domains 2 (220765_s_at), score: 0.63 LMOD1leiomodin 1 (smooth muscle) (203766_s_at), score: 0.74 LPPLIM domain containing preferred translocation partner in lipoma (202822_at), score: 0.61 LRP5low density lipoprotein receptor-related protein 5 (209468_at), score: 0.6 MAN2A2mannosidase, alpha, class 2A, member 2 (202032_s_at), score: 0.67 MCCC1methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) (218440_at), score: 0.61 MEF2Amyocyte enhancer factor 2A (214684_at), score: 0.61 MLXIPMLX interacting protein (202519_at), score: 0.61 NAP1L3nucleosome assembly protein 1-like 3 (204749_at), score: -0.84 NESnestin (218678_at), score: 0.65 NOTCH1Notch homolog 1, translocation-associated (Drosophila) (218902_at), score: 0.59 NOTCH3Notch homolog 3 (Drosophila) (203238_s_at), score: 0.69 NRXN3neurexin 3 (205795_at), score: 0.89 P2RX4purinergic receptor P2X, ligand-gated ion channel, 4 (204088_at), score: 0.65 PDE4Aphosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) (204735_at), score: 0.67 PDGFAplatelet-derived growth factor alpha polypeptide (205463_s_at), score: 0.84 PDLIM3PDZ and LIM domain 3 (209621_s_at), score: 1 PLAUplasminogen activator, urokinase (211668_s_at), score: 0.63 PRSS3protease, serine, 3 (213421_x_at), score: 0.75 PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) (204279_at), score: 0.65 PTK2PTK2 protein tyrosine kinase 2 (207821_s_at), score: 0.61 PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (204469_at), score: 0.64 RAB33ARAB33A, member RAS oncogene family (206039_at), score: 0.59 RELNreelin (205923_at), score: 0.66 RPS4Y1ribosomal protein S4, Y-linked 1 (201909_at), score: 0.62 RTN1reticulon 1 (203485_at), score: 0.94 SCARB1scavenger receptor class B, member 1 (201819_at), score: 0.79 SCG2secretogranin II (chromogranin C) (204035_at), score: 0.65 SCN9Asodium channel, voltage-gated, type IX, alpha subunit (206950_at), score: 0.67 SIM2single-minded homolog 2 (Drosophila) (206558_at), score: 0.8 SLC17A9solute carrier family 17, member 9 (219559_at), score: 0.6 SMAD7SMAD family member 7 (204790_at), score: 0.59 SOBPsine oculis binding protein homolog (Drosophila) (218974_at), score: 0.58 SORT1sortilin 1 (212807_s_at), score: 0.71 STAT4signal transducer and activator of transcription 4 (206118_at), score: 0.65 STBD1starch binding domain 1 (203986_at), score: 0.67 SYNMsynemin, intermediate filament protein (212730_at), score: 0.63 TEAD3TEA domain family member 3 (209454_s_at), score: 0.7 TFPItissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (209676_at), score: 0.67 TM6SF1transmembrane 6 superfamily member 1 (219892_at), score: 0.63 TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (207426_s_at), score: 0.9 TPCN1two pore segment channel 1 (217914_at), score: 0.59 TSPAN12tetraspanin 12 (219274_at), score: 0.77 UBA7ubiquitin-like modifier activating enzyme 7 (203281_s_at), score: 0.69 ZFHX3zinc finger homeobox 3 (208033_s_at), score: 0.62
Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
---|---|---|---|---|---|---|
E-GEOD-3407-raw-cel-1437949557.cel | 1 | 4 | Cockayne | hgu133a | CS | eGFP |
6Twin.CEL | 6 | 2 | DS-twin | hgu133plus2 | none | DS-twin 6 |
5CTwin.CEL | 5 | 2 | DS-twin | hgu133plus2 | Down | DS-twin 5 |
E-GEOD-3860-raw-cel-1561690231.cel | 4 | 5 | HGPS | hgu133a | HGPS | AG10750 |
46A.CEL | 1 | 3 | DS-mosaic | hgu133plus2 | none | DS-mosaic 1 |
E-GEOD-3860-raw-cel-1561690432.cel | 16 | 5 | HGPS | hgu133a | HGPS | AG10750 |
E-GEOD-3860-raw-cel-1561690336.cel | 9 | 5 | HGPS | hgu133a | HGPS | AG10750 |