Previous module | Next module Module #929, TG: 2.2, TC: 2, 354 probes, 354 Entrez genes, 5 conditions

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Expression data for module #929

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Under-expression is coded with green, over-expression with red color.

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MAPKKK cascade

Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways.

activation of MAPK activity

The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

protein modification process

The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).

protein amino acid phosphorylation

The process of introducing a phosphate group on to a protein.

phosphorus metabolic process

The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).

phosphate metabolic process

The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

intracellular signaling cascade

A series of reactions within the cell that occur as a result of a single trigger reaction or compound.

protein kinase cascade

A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

positive regulation of kinase activity

Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

positive regulation of catalytic activity

Any process that activates or increases the activity of an enzyme.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.

regulation of MAP kinase activity

Any process that modulates the frequency, rate or extent of MAP kinase activity.

positive regulation of MAP kinase activity

Any process that activates or increases the frequency, rate or extent of MAP kinase activity.

biopolymer modification

The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer, resulting in a change in its properties.

regulation of kinase activity

Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

post-translational protein modification

The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

cellular protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.

regulation of protein kinase activity

Any process that modulates the frequency, rate or extent of protein kinase activity.

positive regulation of protein kinase activity

Any process that activates or increases the frequency, rate or extent of protein kinase activity.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of catalytic activity

Any process that modulates the activity of an enzyme.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of transferase activity

Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

positive regulation of transferase activity

Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of molecular function

Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding.

all

This term is the most general term possible

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

cellular protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.

protein modification process

The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).

positive regulation of transferase activity

Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.

positive regulation of kinase activity

Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

protein amino acid phosphorylation

The process of introducing a phosphate group on to a protein.

activation of MAPK activity

The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.

positive regulation of protein kinase activity

Any process that activates or increases the frequency, rate or extent of protein kinase activity.

positive regulation of MAP kinase activity

Any process that activates or increases the frequency, rate or extent of MAP kinase activity.

activation of MAPK activity

The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.

Help | Hide | Top The GO tree — Cellular Components

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intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cell surface

The external part of the cell wall and/or plasma membrane.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

melanosome

A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

pigment granule

A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

Id Pvalue ExpCount Count Size
miR-320/320abcd 5.629e-04 18.78 46
372

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ABCB1ATP-binding cassette, sub-family B (MDR/TAP), member 1 (209993_at), score: -0.62 ABHD6abhydrolase domain containing 6 (221679_s_at), score: -0.49 ACLYATP citrate lyase (210337_s_at), score: -0.59 ACTR2ARP2 actin-related protein 2 homolog (yeast) (200727_s_at), score: -0.6 ADAM10ADAM metallopeptidase domain 10 (214895_s_at), score: -0.7 ADAM15ADAM metallopeptidase domain 15 (217007_s_at), score: -0.47 ADO2-aminoethanethiol (cysteamine) dioxygenase (212500_at), score: 0.49 ADRBK1adrenergic, beta, receptor kinase 1 (201401_s_at), score: -0.54 AFF4AF4/FMR2 family, member 4 (219199_at), score: -0.61 AGFG1ArfGAP with FG repeats 1 (213926_s_at), score: -0.58 AGPSalkylglycerone phosphate synthase (205401_at), score: -0.5 AHCYL1S-adenosylhomocysteine hydrolase-like 1 (200848_at), score: -0.47 AKAP10A kinase (PRKA) anchor protein 10 (205045_at), score: -0.55 ANKFY1ankyrin repeat and FYVE domain containing 1 (219868_s_at), score: -0.64 ARF1ADP-ribosylation factor 1 (208750_s_at), score: -0.72 ARF4ADP-ribosylation factor 4 (201096_s_at), score: -0.49 ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) (216266_s_at), score: -0.7 ARHGDIARho GDP dissociation inhibitor (GDI) alpha (213606_s_at), score: -0.52 ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (221039_s_at), score: -0.54 ASB1ankyrin repeat and SOCS box-containing 1 (212819_at), score: 0.51 ASPHaspartate beta-hydroxylase (205808_at), score: -0.59 ATP13A3ATPase type 13A3 (219558_at), score: -0.57 ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (201971_s_at), score: -0.79 ATP6V1C1ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 (202874_s_at), score: -0.46 ATP9AATPase, class II, type 9A (212062_at), score: 0.53 BAG5BCL2-associated athanogene 5 (202984_s_at), score: -0.6 BAZ2Abromodomain adjacent to zinc finger domain, 2A (201353_s_at), score: -0.52 BCAT1branched chain aminotransferase 1, cytosolic (214452_at), score: -0.47 BCHEbutyrylcholinesterase (205433_at), score: -0.58 BCL2L1BCL2-like 1 (215037_s_at), score: -0.54 BCLAF1BCL2-associated transcription factor 1 (201101_s_at), score: -0.58 BET1Lblocked early in transport 1 homolog (S. cerevisiae)-like (220470_at), score: -0.54 BICD2bicaudal D homolog 2 (Drosophila) (209203_s_at), score: -0.47 BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) (210214_s_at), score: -0.53 BSGbasigin (Ok blood group) (208677_s_at), score: -0.52 C10orf28chromosome 10 open reading frame 28 (210455_at), score: -0.49 C11orf2chromosome 11 open reading frame2 (217969_at), score: 0.52 C14orf1chromosome 14 open reading frame 1 (217188_s_at), score: -0.48 C14orf118chromosome 14 open reading frame 118 (219720_s_at), score: -0.66 C18orf10chromosome 18 open reading frame 10 (213617_s_at), score: -0.59 C19orf6chromosome 19 open reading frame 6 (213986_s_at), score: -0.77 C20orf30chromosome 20 open reading frame 30 (220477_s_at), score: -0.55 CACNA2D1calcium channel, voltage-dependent, alpha 2/delta subunit 1 (207050_at), score: -0.66 CALUcalumenin (214845_s_at), score: -0.78 CANXcalnexin (208853_s_at), score: -0.78 CAPN7calpain 7 (203357_s_at), score: -0.51 CAPRIN1cell cycle associated protein 1 (200722_s_at), score: -0.74 CBFBcore-binding factor, beta subunit (206788_s_at), score: -0.54 CCDC6coiled-coil domain containing 6 (204716_at), score: -0.53 CD44CD44 molecule (Indian blood group) (210916_s_at), score: -0.72 CD46CD46 molecule, complement regulatory protein (211574_s_at), score: -0.72 CDC27cell division cycle 27 homolog (S. cerevisiae) (217881_s_at), score: -0.58 CDK6cyclin-dependent kinase 6 (207143_at), score: -0.53 CDV3CDV3 homolog (mouse) (213548_s_at), score: -0.76 CHMchoroideremia (Rab escort protein 1) (207099_s_at), score: -0.66 CLIC4chloride intracellular channel 4 (201559_s_at), score: -0.67 CLINT1clathrin interactor 1 (201768_s_at), score: -0.66 CLIP1CAP-GLY domain containing linker protein 1 (210716_s_at), score: -0.56 CLN3ceroid-lipofuscinosis, neuronal 3 (209275_s_at), score: -0.49 COL1A1collagen, type I, alpha 1 (217430_x_at), score: -0.57 COL6A1collagen, type VI, alpha 1 (212940_at), score: -0.82 COPAcoatomer protein complex, subunit alpha (214336_s_at), score: -0.92 COPS7ACOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) (209029_at), score: -0.46 COPS8COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (202143_s_at), score: -0.49 CPDcarboxypeptidase D (201942_s_at), score: -0.93 CPNE3copine III (202118_s_at), score: -0.46 CRYL1crystallin, lambda 1 (220753_s_at), score: 0.53 CSNK1A1casein kinase 1, alpha 1 (206562_s_at), score: -0.6 CTTNcortactin (201059_at), score: 0.6 CUL4Bcullin 4B (202213_s_at), score: -0.48 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: -0.65 CYTH3cytohesin 3 (206523_at), score: -0.55 DAPK3death-associated protein kinase 3 (203890_s_at), score: -0.6 DAZAP2DAZ associated protein 2 (212595_s_at), score: -0.76 DCBLD2discoidin, CUB and LCCL domain containing 2 (213865_at), score: -0.52 DCP2DCP2 decapping enzyme homolog (S. cerevisiae) (212919_at), score: 0.5 DCTN4dynactin 4 (p62) (218013_x_at), score: -0.55 DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 (208151_x_at), score: -0.58 DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (201211_s_at), score: -1 DEGS1degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) (207431_s_at), score: -0.5 DGCR8DiGeorge syndrome critical region gene 8 (218650_at), score: 0.53 DHDDSdehydrodolichyl diphosphate synthase (218547_at), score: 0.5 DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 9 (212105_s_at), score: -0.92 DNAJB1DnaJ (Hsp40) homolog, subfamily B, member 1 (200664_s_at), score: -0.6 DND1dead end homolog 1 (zebrafish) (57739_at), score: -0.59 DSTdystonin (212253_x_at), score: -0.7 DTX3deltex homolog 3 (Drosophila) (49049_at), score: -0.58 DUSP10dual specificity phosphatase 10 (215501_s_at), score: -0.62 EDIL3EGF-like repeats and discoidin I-like domains 3 (207379_at), score: -0.48 EHMT1euchromatic histone-lysine N-methyltransferase 1 (219339_s_at), score: -0.49 ELK1ELK1, member of ETS oncogene family (210376_x_at), score: -0.56 ENSAendosulfine alpha (221487_s_at), score: -0.52 EPB41L2erythrocyte membrane protein band 4.1-like 2 (201718_s_at), score: -0.69 EPRSglutamyl-prolyl-tRNA synthetase (200841_s_at), score: -0.58 ERLIN1ER lipid raft associated 1 (202444_s_at), score: -0.75 ETS1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (214447_at), score: -0.55 EXOC5exocyst complex component 5 (218748_s_at), score: -0.71 FAM108B1family with sequence similarity 108, member B1 (220285_at), score: -0.6 FAM115Afamily with sequence similarity 115, member A (210529_s_at), score: -0.5 FBN1fibrillin 1 (202765_s_at), score: -0.57 FGFR1fibroblast growth factor receptor 1 (210973_s_at), score: -0.49 FKBP15FK506 binding protein 15, 133kDa (76897_s_at), score: -0.58 FKBP1AFK506 binding protein 1A, 12kDa (210186_s_at), score: -0.65 FN1fibronectin 1 (214701_s_at), score: -0.78 FNTBfarnesyltransferase, CAAX box, beta (204764_at), score: -0.55 FRS2fibroblast growth factor receptor substrate 2 (221308_at), score: -0.66 FUSfusion (involved in t(12;16) in malignant liposarcoma) (217370_x_at), score: -0.57 FXR1fragile X mental retardation, autosomal homolog 1 (201635_s_at), score: -0.63 GABPAGA binding protein transcription factor, alpha subunit 60kDa (210188_at), score: -0.52 GDE1glycerophosphodiester phosphodiesterase 1 (202593_s_at), score: -0.68 GDI2GDP dissociation inhibitor 2 (200008_s_at), score: -0.58 GLE1GLE1 RNA export mediator homolog (yeast) (206920_s_at), score: -0.5 GLUD2glutamate dehydrogenase 2 (215794_x_at), score: -0.46 GLULglutamate-ammonia ligase (glutamine synthetase) (200648_s_at), score: -0.57 GNA12guanine nucleotide binding protein (G protein) alpha 12 (221737_at), score: 0.6 GNA13guanine nucleotide binding protein (G protein), alpha 13 (206917_at), score: -0.84 GNAI3guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 (201179_s_at), score: -0.47 GNRHR2gonadotropin-releasing hormone (type 2) receptor 2 (213852_at), score: 0.51 GNSglucosamine (N-acetyl)-6-sulfatase (203676_at), score: -0.81 GOLGA3golgi autoantigen, golgin subfamily a, 3 (202106_at), score: 0.51 GPR137G protein-coupled receptor 137 (43934_at), score: -0.82 GSTM4glutathione S-transferase mu 4 (204149_s_at), score: -0.51 GTF2Igeneral transcription factor II, i (210892_s_at), score: -0.88 H2AFYH2A histone family, member Y (214500_at), score: -0.58 HIG2hypoxia-inducible protein 2 (218507_at), score: 0.66 HIPK1homeodomain interacting protein kinase 1 (212291_at), score: -0.56 HIPK3homeodomain interacting protein kinase 3 (210148_at), score: -0.56 HMGA1high mobility group AT-hook 1 (210457_x_at), score: -0.5 HN1Lhematological and neurological expressed 1-like (212109_at), score: 0.49 HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2) (200751_s_at), score: -0.53 HNRNPH1heterogeneous nuclear ribonucleoprotein H1 (H) (213470_s_at), score: -0.55 HOXB6homeobox B6 (205366_s_at), score: -0.49 HP1BP3heterochromatin protein 1, binding protein 3 (220633_s_at), score: -0.75 HSPA4heat shock 70kDa protein 4 (211016_x_at), score: -0.69 IFI16interferon, gamma-inducible protein 16 (208965_s_at), score: -0.49 IFNGR1interferon gamma receptor 1 (211676_s_at), score: -0.59 IKZF5IKAROS family zinc finger 5 (Pegasus) (220086_at), score: -0.46 IL13RA1interleukin 13 receptor, alpha 1 (210904_s_at), score: -0.49 IPO8importin 8 (205701_at), score: -0.71 IREB2iron-responsive element binding protein 2 (214666_x_at), score: -0.47 ITGA4integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (205885_s_at), score: -0.55 ITGB5integrin, beta 5 (214021_x_at), score: 0.52 JMJD4jumonji domain containing 4 (218560_s_at), score: 0.63 KCTD20potassium channel tetramerisation domain containing 20 (214849_at), score: -0.54 KIAA1033KIAA1033 (215936_s_at), score: -0.51 KIFC3kinesin family member C3 (209661_at), score: 0.53 KITLGKIT ligand (211124_s_at), score: -0.66 KLHL20kelch-like 20 (Drosophila) (210635_s_at), score: -0.47 KPNA4karyopherin alpha 4 (importin alpha 3) (209653_at), score: -0.64 LAMA4laminin, alpha 4 (202202_s_at), score: 0.52 LAMP1lysosomal-associated membrane protein 1 (201551_s_at), score: -0.61 LATS1LATS, large tumor suppressor, homolog 1 (Drosophila) (219813_at), score: -0.49 LIG4ligase IV, DNA, ATP-dependent (206235_at), score: -0.59 LMAN1lectin, mannose-binding, 1 (203294_s_at), score: -0.78 LOC285412similar to KIAA0737 protein (217448_s_at), score: -0.68 LOC727977hypothetical LOC727977 (205787_x_at), score: -0.48 LOC729148nuclear undecaprenyl pyrophosphate synthase 1 pseudogene (215207_x_at), score: -0.6 LOC730092RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene (216908_x_at), score: -0.7 LRRC2leucine rich repeat containing 2 (219949_at), score: 0.52 LRRC47leucine rich repeat containing 47 (212904_at), score: 0.51 LRRN2leucine rich repeat neuronal 2 (216164_at), score: -0.58 LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (211019_s_at), score: -0.5 M6PRmannose-6-phosphate receptor (cation dependent) (200900_s_at), score: -0.62 MACROD1MACRO domain containing 1 (219188_s_at), score: 0.49 MADDMAP-kinase activating death domain (38398_at), score: 0.64 MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) (36711_at), score: 0.55 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: -0.79 MAP3K7mitogen-activated protein kinase kinase kinase 7 (211537_x_at), score: -0.76 MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (210284_s_at), score: -0.8 MAP4K5mitogen-activated protein kinase kinase kinase kinase 5 (203553_s_at), score: -0.62 MAPK1mitogen-activated protein kinase 1 (208351_s_at), score: -0.73 MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2 (201461_s_at), score: -0.67 MARCH6membrane-associated ring finger (C3HC4) 6 (201737_s_at), score: -0.5 MARCH7membrane-associated ring finger (C3HC4) 7 (202654_x_at), score: -0.64 MAT2Amethionine adenosyltransferase II, alpha (200769_s_at), score: -0.79 MAXMYC associated factor X (210734_x_at), score: -0.74 MAZMYC-associated zinc finger protein (purine-binding transcription factor) (207824_s_at), score: -0.63 MBNL1muscleblind-like (Drosophila) (201151_s_at), score: -0.59 MBNL2muscleblind-like 2 (Drosophila) (205018_s_at), score: -0.82 MBTPS2membrane-bound transcription factor peptidase, site 2 (206473_at), score: -0.67 MED6mediator complex subunit 6 (207079_s_at), score: -0.53 METmet proto-oncogene (hepatocyte growth factor receptor) (211599_x_at), score: -0.56 MFN2mitofusin 2 (216205_s_at), score: -0.65 MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast) (201299_s_at), score: -0.58 MPDU1mannose-P-dolichol utilization defect 1 (209208_at), score: -0.54 MTMR2myotubularin related protein 2 (214649_s_at), score: -0.47 NAB1NGFI-A binding protein 1 (EGR1 binding protein 1) (208047_s_at), score: -0.6 NBPF14neuroblastoma breakpoint family, member 14 (201104_x_at), score: -0.61 NCOA2nuclear receptor coactivator 2 (205732_s_at), score: -0.59 NCRNA00084non-protein coding RNA 84 (214657_s_at), score: -0.53 NDRG3NDRG family member 3 (221082_s_at), score: -0.49 NF1neurofibromin 1 (211094_s_at), score: -0.55 NID1nidogen 1 (202008_s_at), score: -0.54 NNTnicotinamide nucleotide transhydrogenase (202784_s_at), score: -0.54 NONOnon-POU domain containing, octamer-binding (208698_s_at), score: -0.63 NOTCH2Notch homolog 2 (Drosophila) (210756_s_at), score: -0.76 NRASneuroblastoma RAS viral (v-ras) oncogene homolog (202647_s_at), score: -0.49 NRBP1nuclear receptor binding protein 1 (217765_at), score: -0.51 NUMA1nuclear mitotic apparatus protein 1 (214251_s_at), score: -0.57 NUP50nucleoporin 50kDa (218295_s_at), score: -0.55 OASL2'-5'-oligoadenylate synthetase-like (210797_s_at), score: -0.61 OSMRoncostatin M receptor (205729_at), score: -0.62 PAFAH1B1platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa (211547_s_at), score: -0.77 PAOXpolyamine oxidase (exo-N4-amino) (50400_at), score: 0.52 PAPOLApoly(A) polymerase alpha (212720_at), score: -0.64 PARP4poly (ADP-ribose) polymerase family, member 4 (202239_at), score: -0.47 PBLDphenazine biosynthesis-like protein domain containing (219543_at), score: 0.53 PCDHGA11protocadherin gamma subfamily A, 11 (211876_x_at), score: -0.86 PCDHGA3protocadherin gamma subfamily A, 3 (216352_x_at), score: -0.89 PCIF1PDX1 C-terminal inhibiting factor 1 (222045_s_at), score: -0.58 PGRMC1progesterone receptor membrane component 1 (201120_s_at), score: -0.54 PGRMC2progesterone receptor membrane component 2 (213227_at), score: 0.52 PHTF2putative homeodomain transcription factor 2 (217097_s_at), score: -0.86 PICALMphosphatidylinositol binding clathrin assembly protein (215236_s_at), score: -0.68 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (203879_at), score: 0.49 PIP5K1Aphosphatidylinositol-4-phosphate 5-kinase, type I, alpha (211205_x_at), score: -0.65 POLDIP3polymerase (DNA-directed), delta interacting protein 3 (215357_s_at), score: -0.68 POM121POM121 membrane glycoprotein (rat) (212178_s_at), score: -0.49 PPP2R5Dprotein phosphatase 2, regulatory subunit B', delta isoform (211159_s_at), score: -0.58 PRKAA1protein kinase, AMP-activated, alpha 1 catalytic subunit (209799_at), score: -0.54 PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit (201835_s_at), score: -0.67 PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (200604_s_at), score: -0.64 PRKD3protein kinase D3 (211084_x_at), score: -0.67 PRPF4PRP4 pre-mRNA processing factor 4 homolog (yeast) (209162_s_at), score: -0.56 PRPF40APRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) (214941_s_at), score: -0.56 PRPF4BPRP4 pre-mRNA processing factor 4 homolog B (yeast) (211090_s_at), score: -0.7 PRR4proline rich 4 (lacrimal) (204919_at), score: -0.53 PRRX1paired related homeobox 1 (205991_s_at), score: -0.69 PSEN1presenilin 1 (207782_s_at), score: -0.66 PSMB4proteasome (prosome, macropain) subunit, beta type, 4 (202243_s_at), score: 0.53 PSME4proteasome (prosome, macropain) activator subunit 4 (212220_at), score: -0.46 PTBP1polypyrimidine tract binding protein 1 (212016_s_at), score: -0.86 PTPLAD1protein tyrosine phosphatase-like A domain containing 1 (217777_s_at), score: -0.5 PTPN11protein tyrosine phosphatase, non-receptor type 11 (209896_s_at), score: -0.53 PTPN14protein tyrosine phosphatase, non-receptor type 14 (205503_at), score: -0.57 PTPRAprotein tyrosine phosphatase, receptor type, A (213799_s_at), score: -0.46 PTPRBprotein tyrosine phosphatase, receptor type, B (205846_at), score: 0.55 PTPROprotein tyrosine phosphatase, receptor type, O (211600_at), score: -0.61 PXNpaxillin (211823_s_at), score: -0.71 RAB35RAB35, member RAS oncogene family (205461_at), score: -0.61 RAB5ARAB5A, member RAS oncogene family (206113_s_at), score: -0.88 RAB5CRAB5C, member RAS oncogene family (201156_s_at), score: -0.75 RABGAP1LRAB GTPase activating protein 1-like (213982_s_at), score: 0.5 RAD23BRAD23 homolog B (S. cerevisiae) (201223_s_at), score: 0.54 RANBP2RAN binding protein 2 (201711_x_at), score: -0.51 RANBP9RAN binding protein 9 (202583_s_at), score: -0.55 RASA3RAS p21 protein activator 3 (206220_s_at), score: -0.47 RBBP9retinoblastoma binding protein 9 (221440_s_at), score: -0.46 RBM9RNA binding motif protein 9 (213901_x_at), score: -0.57 RCOR3REST corepressor 3 (218344_s_at), score: -0.55 RDXradixin (204969_s_at), score: -0.62 RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian) (209878_s_at), score: -0.48 RFX7regulatory factor X, 7 (218430_s_at), score: -0.46 RHOAras homolog gene family, member A (200059_s_at), score: -0.5 RIN2Ras and Rab interactor 2 (209684_at), score: 0.58 RNASEH2Bribonuclease H2, subunit B (219056_at), score: 0.57 RNF128ring finger protein 128 (219263_at), score: 0.49 RNF13ring finger protein 13 (201779_s_at), score: -0.47 RNF187ring finger protein 187 (212155_at), score: 0.51 RNF19Aring finger protein 19A (220483_s_at), score: -0.58 RNFT1ring finger protein, transmembrane 1 (221194_s_at), score: -0.66 RNGTTRNA guanylyltransferase and 5'-phosphatase (204207_s_at), score: -0.52 RPL31ribosomal protein L31 (221593_s_at), score: 0.56 RPS10P3ribosomal protein S10 pseudogene 3 (217336_at), score: 0.54 RRN3RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) (216902_s_at), score: -0.67 RRP7Bribosomal RNA processing 7 homolog B (S. cerevisiae) (214828_s_at), score: -0.61 RXRBretinoid X receptor, beta (215099_s_at), score: -0.71 RYKRYK receptor-like tyrosine kinase (216976_s_at), score: -0.48 SCAMP1secretory carrier membrane protein 1 (206667_s_at), score: -0.71 SCARB2scavenger receptor class B, member 2 (201647_s_at), score: -0.66 SCML2sex comb on midleg-like 2 (Drosophila) (206147_x_at), score: -0.46 SCYL2SCY1-like 2 (S. cerevisiae) (221220_s_at), score: -0.55 SDC4syndecan 4 (202071_at), score: 0.58 SDHCsuccinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (216591_s_at), score: -0.59 SEC23ASec23 homolog A (S. cerevisiae) (204344_s_at), score: -0.51 SENP3SUMO1/sentrin/SMT3 specific peptidase 3 (215113_s_at), score: -0.68 SEPT10septin 10 (214720_x_at), score: -0.49 SEPT11septin 11 (201308_s_at), score: -0.66 SEPT2septin 2 (200778_s_at), score: -0.61 SFRS1splicing factor, arginine/serine-rich 1 (201742_x_at), score: -0.66 SGCBsarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (205121_at), score: -0.49 SGPP1sphingosine-1-phosphate phosphatase 1 (221268_s_at), score: -0.52 SHC1SHC (Src homology 2 domain containing) transforming protein 1 (201469_s_at), score: -0.5 SKAP2src kinase associated phosphoprotein 2 (216899_s_at), score: -0.58 SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (217473_x_at), score: -0.48 SLC12A4solute carrier family 12 (potassium/chloride transporters), member 4 (209401_s_at), score: -0.64 SLC22A4solute carrier family 22 (organic cation/ergothioneine transporter), member 4 (205896_at), score: 0.51 SLC25A40solute carrier family 25, member 40 (205716_at), score: -0.55 SLC2A1solute carrier family 2 (facilitated glucose transporter), member 1 (201250_s_at), score: 0.51 SLC39A9solute carrier family 39 (zinc transporter), member 9 (217859_s_at), score: -0.46 SLC6A9solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (207043_s_at), score: -0.56 SMAD5SMAD family member 5 (205187_at), score: -0.51 SMEK1SMEK homolog 1, suppressor of mek1 (Dictyostelium) (220368_s_at), score: -0.91 SMG1SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) (210057_at), score: -0.46 SNAP23synaptosomal-associated protein, 23kDa (214544_s_at), score: -0.7 SNTB1syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) (208608_s_at), score: -0.49 SOCS5suppressor of cytokine signaling 5 (209647_s_at), score: -0.48 SP1Sp1 transcription factor (214732_at), score: -0.51 SP110SP110 nuclear body protein (209761_s_at), score: -0.47 SPAG9sperm associated antigen 9 (206748_s_at), score: -0.68 SPPL2Bsignal peptide peptidase-like 2B (215833_s_at), score: -0.5 SPSB3splA/ryanodine receptor domain and SOCS box containing 3 (46256_at), score: 0.48 SPTLC1serine palmitoyltransferase, long chain base subunit 1 (202278_s_at), score: -0.61 SRBD1S1 RNA binding domain 1 (219055_at), score: 0.49 SRPRsignal recognition particle receptor (docking protein) (200917_s_at), score: -0.63 SS18synovial sarcoma translocation, chromosome 18 (216684_s_at), score: -0.76 STAT1signal transducer and activator of transcription 1, 91kDa (AFFX-HUMISGF3A/M97935_MA_at), score: -0.52 STIP1stress-induced-phosphoprotein 1 (212009_s_at), score: -0.73 SYPL1synaptophysin-like 1 (201259_s_at), score: -0.9 TAF9BTAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa (221618_s_at), score: -0.76 TANKTRAF family member-associated NFKB activator (207616_s_at), score: -0.49 TBL1XR1transducin (beta)-like 1 X-linked receptor 1 (221428_s_at), score: -0.55 TGFBR2transforming growth factor, beta receptor II (70/80kDa) (207334_s_at), score: -0.74 TIA1TIA1 cytotoxic granule-associated RNA binding protein (201446_s_at), score: -0.46 TJP1tight junction protein 1 (zona occludens 1) (214168_s_at), score: -0.65 TM9SF4transmembrane 9 superfamily protein member 4 (212194_s_at), score: -0.58 TMCO3transmembrane and coiled-coil domains 3 (220240_s_at), score: -0.57 TMED2transmembrane emp24 domain trafficking protein 2 (204426_at), score: -0.68 TMOD3tropomodulin 3 (ubiquitous) (220800_s_at), score: -0.58 TMX1thioredoxin-related transmembrane protein 1 (208097_s_at), score: -0.6 TOR1AIP1torsin A interacting protein 1 (216100_s_at), score: -0.59 TPM4tropomyosin 4 (212481_s_at), score: -0.48 TRAM1translocation associated membrane protein 1 (210733_at), score: -0.56 TSNtranslin (201504_s_at), score: -0.57 TUBB2Atubulin, beta 2A (209372_x_at), score: -0.53 TWF1twinfilin, actin-binding protein, homolog 1 (Drosophila) (214007_s_at), score: -0.62 UBA6ubiquitin-like modifier activating enzyme 6 (218340_s_at), score: -0.55 UBAP2Lubiquitin associated protein 2-like (201378_s_at), score: -0.48 UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) (200669_s_at), score: -0.74 UBE2Hubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) (221962_s_at), score: -0.57 UBXN4UBX domain protein 4 (212008_at), score: -0.72 USP34ubiquitin specific peptidase 34 (212065_s_at), score: -0.54 UTRNutrophin (213022_s_at), score: -0.65 VAMP3vesicle-associated membrane protein 3 (cellubrevin) (201337_s_at), score: -0.74 VCANversican (215646_s_at), score: -0.51 VCLvinculin (200930_s_at), score: -0.46 VPS37Bvacuolar protein sorting 37 homolog B (S. cerevisiae) (221704_s_at), score: 0.49 VPS4Avacuolar protein sorting 4 homolog A (S. cerevisiae) (217913_at), score: 0.48 WACWW domain containing adaptor with coiled-coil (219679_s_at), score: -0.86 WDR1WD repeat domain 1 (210935_s_at), score: -0.65 XPNPEP1X-prolyl aminopeptidase (aminopeptidase P) 1, soluble (208453_s_at), score: -0.53 YIPF5Yip1 domain family, member 5 (221423_s_at), score: -0.57 YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (210317_s_at), score: -0.64 YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (200641_s_at), score: -0.67 ZFAND5zinc finger, AN1-type domain 5 (217741_s_at), score: -0.75 ZFYzinc finger protein, Y-linked (207247_s_at), score: -0.51 ZMIZ2zinc finger, MIZ-type containing 2 (54970_at), score: 0.51 ZMYND11zinc finger, MYND domain containing 11 (202137_s_at), score: -0.66 ZNF137zinc finger protein 137 (207394_at), score: 0.48 ZNF148zinc finger protein 148 (203319_s_at), score: -0.51 ZNF224zinc finger protein 224 (216983_s_at), score: -0.56 ZNF26zinc finger protein 26 (219595_at), score: 0.56 ZNF629zinc finger protein 629 (213196_at), score: 0.53 ZNF675zinc finger protein 675 (217547_x_at), score: -0.51

Non-Entrez genes

Unknown, score:

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Id sample Experiment ExpName Array Syndrome Cell.line
E-GEOD-3407-raw-cel-1437949938.cel 8 4 Cockayne hgu133a none CSB
E-GEOD-3407-raw-cel-1437949854.cel 7 4 Cockayne hgu133a CS eGFP
4Twin.CEL 4 2 DS-twin hgu133plus2 none DS-twin 4
ctrl c 08-03.CEL 3 1 DS-CC hgu133a none DS-CC 3
E-TABM-263-raw-cel-1515486031.cel 20 6 Cycle hgu133a2 none Cycle 1

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