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immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

antigen processing and presentation of peptide antigen via MHC class I

The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

cell motion

Any process involved in the controlled movement of a cell.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

intracellular signaling cascade

A series of reactions within the cell that occur as a result of a single trigger reaction or compound.

protein kinase cascade

A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

behavior

The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

locomotory behavior

The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

response to external stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

antigen processing and presentation

The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

antigen processing and presentation of peptide antigen

The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

localization of cell

Any process by which a cell is transported to, and/or maintained in, a specific location.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

cell motion

Any process involved in the controlled movement of a cell.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

MHC class I protein complex

A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

MHC protein complex

A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

MHC protein complex

A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.

protein binding

Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

receptor binding

Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

cytokine activity

Functions to control the survival, growth, differentiation and effector function of tissues and cells.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.

MHC class I receptor activity

Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

Id	Pvalue	ExpCount	Count	Size	Term
GO:0002376	7.601e-08	15.61	44 C1R, C1S, CBLB, CCL2, CCRL1, CD55, CD97, CLEC7A, CSF1, CXCL3, DPP4, ERAP2, GEM, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HMOX1, HOXB7, ICAM1, IL11, IL1RAP, IL1RL1, IL6, IL8, JARID2, LIF, LY96, NFIL3, NFKB1, NP, OSTM1, PSMB8, RUNX1, SECTM1, SHB, SIX1, SOD2, SOX4, TNFRSF14, TNFSF4, TRIM22, VEGFA	466	immune system process
GO:0032501	3.860e-07	53.95	95 ACSL1, ADRA2A, ANGPTL2, ANGPTL4, ANO1, AQP1, BHLHE40, CCL2, COL13A1, COL15A1, COL7A1, CREG1, CSF1, CST3, DCN, DGKD, DKK2, EGR2, EGR3, EPHB3, ERAP2, F10, F3, FGF2, FGF7, FLG, FNDC3A, FOSB, GAA, GAP43, GDF5, GPNMB, HBEGF, HHEX, HK2, HMOX1, HOXB6, HOXB7, HOXC10, HOXD11, HSPB7, HTR2A, HTR2B, IDUA, IL11, IL6, IL8, ITPR3, JARID2, KCNMB4, KCNN4, LIF, MAN2B1, MAP2K3, MEIS1, MEOX1, NFKB1, NINJ1, NKX3-1, NOVA1, NP, NPTX1, NR3C1, NR4A3, OSTM1, PDGFA, PLAUR, PPARD, PPL, PTN, RABGGTB, RPS4Y1, RUNX1, SECTM1, SEMA5A, SEPP1, SHB, SIX1, SLC19A2, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, TBX3, THBD, TNFAIP2, TNFRSF11B, TNS3, TNXB, TPP1, USP22, VEGFA, ZMYM6	1611	multicellular organismal process
GO:0009611	2.027e-06	7.569	27 C1R, C1S, CCL2, CD55, CD97, CLEC7A, CXCL3, F10, F3, FGF7, GAP43, HBEGF, HMOX1, IL1RAP, IL6, IL8, JMJD3, LY96, MAP2K3, NFKB1, NINJ1, PDGFA, PLAUR, PPARD, SOD2, THBD, TPST1	226	response to wounding
GO:0006955	5.929e-06	9.612	30 C1R, C1S, CBLB, CCL2, CCRL1, CD55, CD97, CLEC7A, CXCL3, ERAP2, GEM, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HMOX1, ICAM1, IL1RAP, IL1RL1, IL6, IL8, LIF, LY96, NFIL3, PSMB8, SECTM1, TNFRSF14, TNFSF4, TRIM22	287	immune response
GO:0009605	1.033e-05	12.19	34 BHLHE40, C1R, C1S, CCL2, CCRL1, CD55, CD97, CLEC7A, CXCL3, EGR2, F10, F3, FGF2, FGF7, GAP43, HBEGF, HMOX1, IL1RAP, IL6, IL8, JMJD3, LY96, MAP2K3, NFKB1, NINJ1, NPC1, NR4A3, PDGFA, PLAUR, PPARD, SOD2, THBD, TPST1, VEGFA	364	response to external stimulus
GO:0007275	2.480e-05	42.1	75 ANGPTL2, ANGPTL4, ANO1, CCL2, COL13A1, COL15A1, COL7A1, CREG1, CSF1, CST3, DCN, DGKD, DKK2, EGR2, EGR3, EPHB3, FGF2, FGF7, FLG, FNDC3A, FOSB, GAA, GAP43, GDF5, GPNMB, HBEGF, HHEX, HMOX1, HOXB6, HOXB7, HOXC10, HOXD11, HTR2B, IDUA, IL11, IL6, IL8, JARID2, LIF, MEIS1, MEOX1, NFKB1, NINJ1, NKX3-1, NP, NPTX1, NR3C1, NR4A3, OSTM1, PDGFA, PPARD, PPL, PTN, RPS4Y1, RUNX1, SECTM1, SEMA5A, SEPP1, SHB, SIX1, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, TBX3, THBD, TNFAIP2, TNFRSF11B, TNS3, TPP1, USP22, VEGFA, ZMYM6	1257	multicellular organismal development
GO:0048513	4.377e-05	24.41	51 ANGPTL4, CCL2, COL15A1, COL7A1, CSF1, CST3, DCN, EGR2, EGR3, FGF2, FGF7, FNDC3A, GAA, GAP43, GDF5, GPNMB, HBEGF, HHEX, HMOX1, HOXB6, HOXB7, HTR2B, IDUA, IL11, IL6, IL8, JARID2, LIF, NFKB1, NINJ1, NP, NR3C1, NR4A3, OSTM1, PPARD, PPL, PTN, RUNX1, SECTM1, SEMA5A, SEPP1, SHB, SIX1, SOD2, SOX4, SPRY2, TBX3, TNFAIP2, TNFRSF11B, TNS3, VEGFA	729	organ development
GO:0050896	4.490e-05	44.38	77 ADRA2A, ANGPTL4, BDKRB1, BHLHE40, C1R, C1S, CBLB, CCL2, CCRL1, CD55, CD97, CLEC7A, CST3, CXCL3, DGKD, DPP4, EGLN2, EGR2, ERAP2, F10, F3, FGF2, FGF7, FOSB, GAA, GADD45A, GAP43, GEM, GPX3, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HMOX1, HSPB7, HTR2A, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6, IL8, JMJD3, KCNMB4, KCNN4, LIF, LY96, MAN2B1, MAP2K3, MAP3K4, NFIL3, NFKB1, NINJ1, NOVA1, NPC1, NR3C1, NR4A3, PDGFA, PLAUR, PPARD, PSMB8, PTN, SECTM1, SEPP1, SOCS2, SOD2, SOD3, THBD, TNFRSF14, TNFSF4, TP53I11, TPST1, TRIB1, TRIM22, VEGFA	1325	response to stimulus
GO:0007154	1.691e-04	63.9	98 ADRA2A, ANGPTL2, ANGPTL4, ASAP2, BDKRB1, BHLHE40, CASP1, CBLB, CCL2, CCRL1, CD97, CDC42SE1, CLEC7A, DGKD, DKK2, ECM1, EGLN2, EGR2, EGR3, EPHB3, FAM13B, FGF2, FGF7, GAP43, GDF5, GEM, GNAL, GPR37, GRN, HBEGF, HHEX, HMOX1, HTR2A, HTR2B, HTRA1, IFITM1, IL11, IL15RA, IL1RAP, IL1RL1, IL6, IL8, ITPR3, KCNMB4, LGR4, LIF, LY96, LYN, MAP2K3, MAP3K4, MAP3K7IP2, MFAP4, MTSS1, NAMPT, NET1, NFATC1, NFKB1, NOVA1, NPC1, NPTX1, NR3C1, PDGFA, PIAS4, PIK3CD, PLAUR, PMEPA1, PPAP2A, PPARD, PTN, RALGPS2, RAPGEF2, RCAN2, RGS2, RGS3, RRAD, SECTM1, SEMA5A, SH2B2, SHB, SIX1, SOCS2, SOD2, SOX4, SPRED2, SPRY2, SPRY4, STK38L, TBX3, TEX2, TNFRSF11B, TNFRSF14, TNFSF4, TNXB, TP53BP2, TRAF3, TRAF3IP2, TRIB1, VEGFA	1908	cell communication
GO:0008284	1.923e-04	6.263	21 ADRA2A, CCL2, CCND2, CSF1, FGF2, FGF7, HBEGF, HOXC10, HTR2A, IL11, IL6, LIF, NAMPT, NP, PDGFA, PTN, SOX4, TBX3, TNFSF4, TNS3, VEGFA	187	positive regulation of cell proliferation
GO:0007610	2.901e-04	5.392	19 CCL2, CCRL1, CXCL3, EGR2, FGF2, FOSB, GAA, HTR2A, IL6, IL8, MAN2B1, NOVA1, NR4A3, PDGFA, PLAUR, PTN, SEPP1, SOD2, VEGFA	161	behavior
GO:0032502	4.285e-04	62.63	95 ANGPTL2, ANGPTL4, ANO1, CASP1, CASP4, CCL2, CDC42SE1, COL13A1, COL15A1, COL7A1, CREG1, CSF1, CST3, DCN, DGKD, DKK2, EGLN2, EGR2, EGR3, EPHB3, FGF2, FGF7, FLG, FNDC3A, FOSB, GAA, GADD45A, GAP43, GDF5, GNPTAB, GPNMB, HBEGF, HHEX, HMOX1, HOXB6, HOXB7, HOXC10, HOXD11, HTR2A, HTR2B, HTRA1, IDUA, IL11, IL6, IL8, JARID2, LIF, MEIS1, MEOX1, MTSS1, NET1, NFKB1, NINJ1, NKX3-1, NP, NPTX1, NR3C1, NR4A3, OSTM1, PDGFA, PHLDA1, PPARD, PPL, PTN, RPS4Y1, RUNX1, SECTM1, SEMA5A, SEPP1, SERPINB2, SHB, SIX1, SOCS2, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, SULF1, TBX3, THBD, TM2D1, TNFAIP2, TNFAIP8, TNFRSF11B, TNFRSF14, TNFRSF1B, TNS3, TP53BP2, TPP1, TRAF3, USP22, VEGFA, ZMYM6	1870	developmental process
GO:0042127	4.453e-04	12.59	31 ADRA2A, CCL2, CCND2, CSF1, FGF2, FGF7, GPNMB, HBEGF, HHEX, HMOX1, HOXC10, HTR2A, IFITM1, IL11, IL6, IL8, JARID2, LIF, NAMPT, NP, PDGFA, PPAP2A, PTN, SOD2, SOX4, TBX3, TNFSF4, TNS3, TP53I11, TRIB1, VEGFA	376	regulation of cell proliferation
GO:0010646	9.627e-04	13.8	32 ASAP2, BHLHE40, CASP1, DKK2, ECM1, EGR2, HHEX, HMOX1, HTR2A, HTR2B, HTRA1, IL11, IL1RL1, IL6, KCNMB4, LIF, MAP3K7IP2, NET1, NPC1, PPARD, RAPGEF2, RGS2, RGS3, SECTM1, SOCS2, SOX4, SPRED2, SPRY2, SPRY4, TRAF3IP2, TRIB1, VEGFA	412	regulation of cell communication
GO:0048518	1.212e-03	28.4	52 ABLIM3, ADRA2A, ANGPTL4, C1R, C1S, CASP1, CASP4, CCL2, CCND2, CD55, CSF1, ECM1, EGLN2, EGR2, FGF2, FGF7, GDF5, HBEGF, HHEX, HMOX1, HOXC10, HTR2A, HTR2B, ICAM1, IL11, IL6, IL8, KCNN4, LIF, MAP2K3, MAP3K7IP2, MEOX1, NAMPT, NFKB1, NP, NR4A3, PDGFA, PPARD, PTN, RUNX1, SECTM1, SOD2, SOX4, TBX3, TM2D1, TNFSF4, TNS3, TP53BP2, TRAF3, TRAF3IP2, USP22, VEGFA	848	positive regulation of biological process
GO:0002474	1.741e-03	0.5693	6 ERAP2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	17	antigen processing and presentation of peptide antigen via MHC class I
GO:0065007	2.346e-03	124.2	156 ABLIM3, ACSL1, ADRA2A, AEBP1, ANGPTL2, ANGPTL4, ARID5A, ASAP2, BDKRB1, BHLHE40, C1R, C1S, CASP1, CASP4, CBLB, CCL2, CCND2, CCRL1, CD55, CD97, CDC42SE1, CLEC7A, CREG1, CSF1, CST3, DGKD, DKK2, DNAJC1, DPP4, ECM1, EGLN2, EGR2, EGR3, EPHB3, ERAP2, F10, F3, FAM13B, FGF2, FGF7, FOSB, GAA, GADD45A, GAP43, GDF5, GEM, GNAL, GPNMB, GPR37, GRN, HBEGF, HHEX, HMOX1, HOXB6, HOXB7, HOXC10, HSD17B11, HSPB7, HTR2A, HTR2B, HTRA1, ICAM1, IDUA, IFITM1, IL11, IL15RA, IL1RAP, IL1RL1, IL6, IL8, ITPR3, JARID2, JMJD3, KANK1, KCNMB4, KCNN4, KHDRBS3, LGR4, LIF, LMCD1, LY96, LYN, MAF, MAP2K3, MAP3K4, MAP3K7IP2, MEIS1, MEIS3P1, MEOX1, MFAP4, MTSS1, NAMPT, NET1, NFATC1, NFIB, NFIL3, NFKB1, NKX3-1, NP, NPC1, NPC2, NR3C1, NR4A3, PDGFA, PDGFD, PIAS4, PIK3CD, PLAUR, PMEPA1, PPAP2A, PPARD, PSMB8, PTN, RALGPS2, RAPGEF2, RCAN2, RGS2, RGS3, RRAD, RUNX1, SECTM1, SERPINB2, SH2B2, SHB, SIX1, SOCS2, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, STK38L, TBX3, TEX2, THBD, TM2D1, TNFAIP8, TNFRSF11B, TNFRSF14, TNFSF4, TNS3, TNXB, TP53BP2, TP53I11, TPP1, TRAF3, TRAF3IP2, TRIB1, TRIM22, USP22, VEGFA, ZBTB20, ZKSCAN3, ZNF35, ZNF672	3707	biological regulation
GO:0007165	2.380e-03	59.21	88 ADRA2A, ANGPTL2, ANGPTL4, ASAP2, BDKRB1, CASP1, CBLB, CCL2, CCRL1, CD97, CDC42SE1, CLEC7A, DGKD, DKK2, ECM1, EGLN2, EPHB3, FAM13B, FGF2, FGF7, GAP43, GDF5, GEM, GNAL, GPR37, GRN, HBEGF, HHEX, HMOX1, HTR2A, HTR2B, HTRA1, IFITM1, IL11, IL15RA, IL1RAP, IL1RL1, IL6, IL8, ITPR3, LGR4, LIF, LY96, LYN, MAP2K3, MAP3K4, MAP3K7IP2, MFAP4, MTSS1, NAMPT, NET1, NFATC1, NFKB1, NR3C1, PDGFA, PIAS4, PIK3CD, PLAUR, PMEPA1, PPAP2A, PPARD, PTN, RALGPS2, RAPGEF2, RCAN2, RGS2, RGS3, RRAD, SECTM1, SH2B2, SHB, SOCS2, SOD2, SOX4, SPRED2, SPRY2, SPRY4, STK38L, TEX2, TNFRSF11B, TNFRSF14, TNFSF4, TNXB, TP53BP2, TRAF3, TRAF3IP2, TRIB1, VEGFA	1768	signal transduction
GO:0007626	2.983e-03	3.316	13 CCL2, CCRL1, CXCL3, FGF2, GAA, IL6, IL8, NOVA1, PDGFA, PLAUR, SEPP1, SOD2, VEGFA	99	locomotory behavior
GO:0006928	3.095e-03	8.875	23 ADRA2A, CCL2, CD97, CSF1, EGR2, EPHB3, FGF2, GAP43, HBEGF, HMOX1, ICAM1, IL6, IL8, MTSS1, PDGFA, PLAUR, PPAP2A, PPARD, SEMA5A, SIX1, TNS3, TRIB1, VEGFA	265	cell motion
GO:0051674	3.095e-03	8.875	23 ADRA2A, CCL2, CD97, CSF1, EGR2, EPHB3, FGF2, GAP43, HBEGF, HMOX1, ICAM1, IL6, IL8, MTSS1, PDGFA, PLAUR, PPAP2A, PPARD, SEMA5A, SIX1, TNS3, TRIB1, VEGFA	265	localization of cell
GO:0009887	3.340e-03	10.18	25 ANGPTL4, CCL2, COL15A1, CST3, DCN, FGF2, GAA, HHEX, HMOX1, HOXB6, HOXB7, IDUA, IL6, IL8, JARID2, NR4A3, SEMA5A, SHB, SIX1, SOD2, SPRY2, TBX3, TNFAIP2, TNFRSF11B, VEGFA	304	organ morphogenesis
GO:0048731	4.053e-03	33.06	56 ANGPTL4, CCL2, COL15A1, COL7A1, CSF1, CST3, DCN, EGR2, EGR3, EPHB3, FGF2, FGF7, FNDC3A, GAA, GAP43, GDF5, GPNMB, HBEGF, HHEX, HMOX1, HOXB6, HOXB7, HOXC10, HTR2B, IDUA, IL11, IL6, IL8, JARID2, LIF, NFKB1, NINJ1, NP, NPTX1, NR3C1, NR4A3, OSTM1, PPARD, PPL, PTN, RUNX1, SECTM1, SEMA5A, SEPP1, SHB, SIX1, SOD2, SOX11, SOX4, SPRY2, TBX3, TNFAIP2, TNFRSF11B, TNS3, TPP1, VEGFA	987	system development
GO:0006954	4.527e-03	5.024	16 C1R, C1S, CCL2, CD55, CD97, CLEC7A, CXCL3, HMOX1, IL1RAP, IL6, IL8, JMJD3, LY96, MAP2K3, NFKB1, TPST1	150	inflammatory response
GO:0019882	4.984e-03	1.34	8 ERAP2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, ICAM1, PSMB8	40	antigen processing and presentation
GO:0048002	5.393e-03	0.7033	6 ERAP2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	21	antigen processing and presentation of peptide antigen
GO:0042060	6.264e-03	2.646	11 F10, F3, GAP43, HBEGF, HMOX1, IL6, NINJ1, PDGFA, PLAUR, PPARD, THBD	79	wound healing
GO:0007243	8.172e-03	9.578	23 ADRA2A, CASP1, CCL2, ECM1, FGF2, HMOX1, HTR2B, IL11, IL1RL1, IL6, LIF, LY96, MAP2K3, MAP3K4, MAP3K7IP2, PPARD, RAPGEF2, RGS3, SECTM1, SOCS2, STK38L, TRAF3IP2, TRIB1	286	protein kinase cascade
GO:0050789	8.361e-03	117.8	147 ABLIM3, ACSL1, ADRA2A, AEBP1, ANGPTL2, ANGPTL4, ARID5A, ASAP2, BDKRB1, BHLHE40, C1R, C1S, CASP1, CASP4, CBLB, CCL2, CCND2, CCRL1, CD55, CD97, CDC42SE1, CLEC7A, CREG1, CSF1, CST3, DGKD, DKK2, DNAJC1, DPP4, ECM1, EGLN2, EGR2, EGR3, EPHB3, FAM13B, FGF2, FGF7, FOSB, GAA, GADD45A, GAP43, GDF5, GEM, GNAL, GPNMB, GPR37, GRN, HBEGF, HHEX, HMOX1, HOXB7, HOXC10, HSPB7, HTR2A, HTR2B, HTRA1, ICAM1, IFITM1, IL11, IL15RA, IL1RAP, IL1RL1, IL6, IL8, ITPR3, JARID2, JMJD3, KANK1, KCNMB4, KCNN4, KHDRBS3, LGR4, LIF, LMCD1, LY96, LYN, MAF, MAP2K3, MAP3K4, MAP3K7IP2, MEIS1, MEIS3P1, MEOX1, MFAP4, MTSS1, NAMPT, NET1, NFATC1, NFIB, NFIL3, NFKB1, NKX3-1, NP, NPC1, NPC2, NR3C1, NR4A3, PDGFA, PDGFD, PIAS4, PIK3CD, PLAUR, PMEPA1, PPAP2A, PPARD, PTN, RALGPS2, RAPGEF2, RCAN2, RGS2, RGS3, RRAD, RUNX1, SECTM1, SERPINB2, SH2B2, SHB, SIX1, SOCS2, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, STK38L, TBX3, TEX2, TM2D1, TNFAIP8, TNFRSF11B, TNFRSF14, TNFSF4, TNS3, TNXB, TP53BP2, TP53I11, TRAF3, TRAF3IP2, TRIB1, TRIM22, USP22, VEGFA, ZBTB20, ZKSCAN3, ZNF35, ZNF672	3518	regulation of biological process
GO:0008283	9.313e-03	18.72	36 ADRA2A, CCL2, CCND2, CREG1, CSF1, FGF2, FGF7, GPNMB, HBEGF, HHEX, HMOX1, HOXC10, HTR2A, IFITM1, IL11, IL15RA, IL6, IL8, JARID2, LIF, NAMPT, NP, PDGFA, PDGFD, PPAP2A, PPARD, PTN, SHB, SOD2, SOX4, TBX3, TNFSF4, TNS3, TP53I11, TRIB1, VEGFA	559	cell proliferation
GO:0009966	1.018e-02	12.43	27 ASAP2, CASP1, DKK2, ECM1, HHEX, HMOX1, HTR2B, HTRA1, IL11, IL1RL1, IL6, LIF, MAP3K7IP2, NET1, PPARD, RAPGEF2, RGS2, RGS3, SECTM1, SOCS2, SOX4, SPRED2, SPRY2, SPRY4, TRAF3IP2, TRIB1, VEGFA	371	regulation of signal transduction
GO:0051239	1.101e-02	10.48	24 ANGPTL4, BHLHE40, CSF1, CST3, EGR2, FGF2, GAA, GDF5, HBEGF, HHEX, HMOX1, HSPB7, HTR2A, IL6, KCNMB4, LIF, MAP2K3, NFKB1, NP, PDGFA, RUNX1, SIX1, TBX3, TNFRSF11B	313	regulation of multicellular organismal process
GO:0048856	1.131e-02	40.42	63 ANGPTL4, CCL2, CDC42SE1, COL15A1, COL7A1, CSF1, CST3, DCN, DGKD, EGLN2, EGR2, EGR3, EPHB3, FGF2, FGF7, FNDC3A, GAA, GAP43, GDF5, GPNMB, HBEGF, HHEX, HMOX1, HOXB6, HOXB7, HOXC10, HTR2B, HTRA1, IDUA, IL11, IL6, IL8, JARID2, LIF, MTSS1, NET1, NFKB1, NINJ1, NP, NPTX1, NR3C1, NR4A3, OSTM1, PPARD, PPL, PTN, RUNX1, SECTM1, SEMA5A, SEPP1, SHB, SIX1, SOCS2, SOD2, SOX11, SOX4, SPRY2, TBX3, TNFAIP2, TNFRSF11B, TNS3, TPP1, VEGFA	1207	anatomical structure development
GO:0002685	1.226e-02	0.3014	4 HMOX1, ICAM1, IL6, VEGFA	9	regulation of leukocyte migration
GO:0033135	1.290e-02	0.134	3 IL11, IL6, LIF	4	regulation of peptidyl-serine phosphorylation
GO:0033138	1.290e-02	0.134	3 IL11, IL6, LIF	4	positive regulation of peptidyl-serine phosphorylation
GO:0050794	1.348e-02	114	142 ABLIM3, ACSL1, ADRA2A, AEBP1, ANGPTL2, ANGPTL4, ARID5A, ASAP2, BDKRB1, BHLHE40, CASP1, CASP4, CBLB, CCL2, CCND2, CCRL1, CD97, CDC42SE1, CLEC7A, CREG1, CSF1, CST3, DGKD, DKK2, DNAJC1, DPP4, ECM1, EGLN2, EGR2, EGR3, EPHB3, FAM13B, FGF2, FGF7, FOSB, GADD45A, GAP43, GDF5, GEM, GNAL, GPNMB, GPR37, GRN, HBEGF, HHEX, HMOX1, HOXB7, HOXC10, HTR2A, HTR2B, HTRA1, ICAM1, IFITM1, IL11, IL15RA, IL1RAP, IL1RL1, IL6, IL8, ITPR3, JARID2, JMJD3, KANK1, KCNMB4, KCNN4, KHDRBS3, LGR4, LIF, LMCD1, LY96, LYN, MAF, MAP2K3, MAP3K4, MAP3K7IP2, MEIS1, MEIS3P1, MEOX1, MFAP4, MTSS1, NAMPT, NET1, NFATC1, NFIB, NFIL3, NFKB1, NKX3-1, NP, NPC1, NPC2, NR3C1, NR4A3, PDGFA, PDGFD, PIAS4, PIK3CD, PLAUR, PMEPA1, PPAP2A, PPARD, PTN, RALGPS2, RAPGEF2, RCAN2, RGS2, RGS3, RRAD, RUNX1, SECTM1, SERPINB2, SH2B2, SHB, SIX1, SOCS2, SOD2, SOX11, SOX4, SPRED2, SPRY2, SPRY4, STK38L, TBX3, TEX2, TM2D1, TNFAIP8, TNFRSF11B, TNFRSF14, TNFSF4, TNS3, TNXB, TP53BP2, TP53I11, TRAF3, TRAF3IP2, TRIB1, TRIM22, USP22, VEGFA, ZBTB20, ZKSCAN3, ZNF35, ZNF672	3404	regulation of cellular process
GO:0048522	1.667e-02	26.39	45 ABLIM3, ADRA2A, CASP1, CASP4, CCL2, CCND2, CSF1, ECM1, EGR2, FGF2, FGF7, GDF5, HBEGF, HHEX, HMOX1, HOXC10, HTR2A, HTR2B, ICAM1, IL11, IL6, LIF, MAP2K3, MAP3K7IP2, MEOX1, NAMPT, NFKB1, NP, NR4A3, PDGFA, PPARD, PTN, RUNX1, SECTM1, SOD2, SOX4, TBX3, TM2D1, TNFSF4, TNS3, TP53BP2, TRAF3, TRAF3IP2, USP22, VEGFA	788	positive regulation of cellular process
GO:0030335	1.793e-02	1.273	7 CSF1, FGF2, HBEGF, ICAM1, IL6, PDGFA, VEGFA	38	positive regulation of cell migration
GO:0010740	2.120e-02	3.148	11 CASP1, ECM1, HMOX1, HTR2B, IL11, IL6, LIF, MAP3K7IP2, PPARD, SECTM1, TRAF3IP2	94	positive regulation of protein kinase cascade
GO:0007166	2.167e-02	22.87	40 ADRA2A, BDKRB1, CBLB, CCL2, CCRL1, CD97, DGKD, DKK2, EPHB3, FGF2, FGF7, GAP43, GDF5, GEM, GNAL, GPR37, HBEGF, HHEX, HTR2A, HTR2B, HTRA1, IFITM1, IL6, IL8, ITPR3, LGR4, LIF, LY96, MTSS1, PDGFA, PIAS4, PPAP2A, PTN, RGS2, RGS3, SOCS2, SOX4, TNFRSF14, TRIB1, VEGFA	683	cell surface receptor linked signal transduction
GO:0007267	2.371e-02	8.54	20 BHLHE40, CD97, EGR2, EGR3, FGF2, GDF5, HTR2A, IL11, IL6, IL8, KCNMB4, LIF, NAMPT, NOVA1, NPTX1, PDGFA, SEMA5A, SIX1, SPRY2, TBX3	255	cell-cell signaling
GO:0040012	2.443e-02	2.713	10 CSF1, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, PDGFA, TRIB1, VEGFA	81	regulation of locomotion
GO:0006935	2.526e-02	2.244	9 CCL2, CCRL1, CXCL3, FGF2, IL6, IL8, PDGFA, PLAUR, VEGFA	67	chemotaxis
GO:0042330	2.526e-02	2.244	9 CCL2, CCRL1, CXCL3, FGF2, IL6, IL8, PDGFA, PLAUR, VEGFA	67	taxis
GO:0006952	2.553e-02	8.607	20 C1R, C1S, CCL2, CD55, CD97, CLEC7A, CST3, CXCL3, HLA-B, HMOX1, IL1RAP, IL1RL1, IL6, IL8, JMJD3, KCNN4, LY96, MAP2K3, NFKB1, TPST1	257	defense response
GO:0050900	2.744e-02	1.005	6 CCL2, HMOX1, ICAM1, IL6, IL8, VEGFA	30	leukocyte migration
GO:0010627	2.762e-02	3.818	12 CASP1, ECM1, HMOX1, HTR2B, IL11, IL1RL1, IL6, LIF, MAP3K7IP2, PPARD, SECTM1, TRAF3IP2	114	regulation of protein kinase cascade
GO:0009888	2.809e-02	4.957	14 COL7A1, CST3, FGF7, GAA, GAP43, GDF5, GPNMB, NINJ1, NR4A3, PPARD, PPL, PTN, SECTM1, TBX3	148	tissue development
GO:0006950	3.126e-02	28.23	46 ADRA2A, ANGPTL4, C1R, C1S, CCL2, CD55, CD97, CLEC7A, CST3, CXCL3, DPP4, EGLN2, F10, F3, FGF7, GADD45A, GAP43, GPX3, HBEGF, HLA-B, HMOX1, HSPB7, HTR2A, IL1RAP, IL1RL1, IL6, IL8, JMJD3, KCNN4, LY96, MAP2K3, MAP3K4, NFKB1, NINJ1, NPC1, PDGFA, PLAUR, PPARD, SEPP1, SOD2, SOD3, THBD, TP53I11, TPST1, TRIB1, VEGFA	843	response to stress
GO:0040011	3.152e-02	7.502	18 CCL2, CCRL1, CSF1, CXCL3, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, PDGFA, PLAUR, PPAP2A, PPARD, SIX1, TNS3, TRIB1, VEGFA	224	locomotion
GO:0051272	3.189e-02	1.44	7 CSF1, FGF2, HBEGF, ICAM1, IL6, PDGFA, VEGFA	43	positive regulation of cell motion
GO:0016477	3.255e-02	5.66	15 CCL2, CSF1, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, PDGFA, PPAP2A, PPARD, SIX1, TNS3, TRIB1, VEGFA	169	cell migration
GO:0045859	3.255e-02	5.66	15 ADRA2A, CCND2, CSF1, DGKD, FGF2, GADD45A, GAP43, HTR2A, MAP2K3, MAP3K4, PPAP2A, RGS3, SPRY2, SPRY4, TRIB1	169	regulation of protein kinase activity
GO:0009653	3.262e-02	22.74	39 ANGPTL4, CCL2, CDC42SE1, COL15A1, CST3, DCN, DGKD, EGLN2, EGR2, EPHB3, FGF2, GAA, GAP43, GDF5, HHEX, HMOX1, HOXB6, HOXB7, HOXC10, HTRA1, IDUA, IL6, IL8, JARID2, MTSS1, NET1, NINJ1, NR4A3, PPL, SEMA5A, SHB, SIX1, SOCS2, SOD2, SPRY2, TBX3, TNFAIP2, TNFRSF11B, VEGFA	679	anatomical structure morphogenesis
GO:0010648	3.433e-02	2.88	10 DKK2, HHEX, HTR2A, HTRA1, IL1RL1, NPC1, RGS2, RGS3, SOCS2, TRIB1	86	negative regulation of cell communication
GO:0009967	3.440e-02	4.521	13 CASP1, ECM1, HMOX1, HTR2B, IL11, IL6, LIF, MAP3K7IP2, PPARD, SECTM1, SOX4, TRAF3IP2, VEGFA	135	positive regulation of signal transduction
GO:0051046	3.459e-02	1.909	8 DNAJC1, HMOX1, HTR2A, IL11, IL6, KCNMB4, KCNN4, LIF	57	regulation of secretion
GO:0001525	3.500e-02	3.416	11 ANGPTL4, COL15A1, FGF2, HHEX, HMOX1, IL6, IL8, SEMA5A, SHB, TNFAIP2, VEGFA	102	angiogenesis
GO:0043549	3.849e-02	5.794	15 ADRA2A, CCND2, CSF1, DGKD, FGF2, GADD45A, GAP43, HTR2A, MAP2K3, MAP3K4, PPAP2A, RGS3, SPRY2, SPRY4, TRIB1	173	regulation of kinase activity
GO:0030334	3.956e-02	2.445	9 CSF1, FGF2, HBEGF, HMOX1, ICAM1, IL6, PDGFA, TRIB1, VEGFA	73	regulation of cell migration
GO:0002763	3.981e-02	0.4354	4 CSF1, LIF, NFKB1, RUNX1	13	positive regulation of myeloid leukocyte differentiation
GO:0048514	3.991e-02	4.052	12 ANGPTL4, COL15A1, CST3, FGF2, HHEX, HMOX1, IL6, IL8, SEMA5A, SHB, TNFAIP2, VEGFA	121	blood vessel morphogenesis
GO:0048870	4.151e-02	5.861	15 CCL2, CSF1, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, PDGFA, PPAP2A, PPARD, SIX1, TNS3, TRIB1, VEGFA	175	cell motility
GO:0003013	4.632e-02	3.048	10 ERAP2, GAA, HBEGF, HMOX1, HSPB7, HTR2A, HTR2B, KCNMB4, MAP2K3, SOD2	91	circulatory system process
GO:0008015	4.632e-02	3.048	10 ERAP2, GAA, HBEGF, HMOX1, HSPB7, HTR2A, HTR2B, KCNMB4, MAP2K3, SOD2	91	blood circulation
GO:0010647	4.735e-02	4.756	13 CASP1, ECM1, HMOX1, HTR2B, IL11, IL6, LIF, MAP3K7IP2, PPARD, SECTM1, SOX4, TRAF3IP2, VEGFA	142	positive regulation of cell communication
GO:0051338	4.856e-02	5.995	15 ADRA2A, CCND2, CSF1, DGKD, FGF2, GADD45A, GAP43, HTR2A, MAP2K3, MAP3K4, PPAP2A, RGS3, SPRY2, SPRY4, TRIB1	179	regulation of transferase activity

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005576	6.852e-16	21.62	68 AEBP1, ANGPTL2, ANGPTL4, APOD, C1R, C1S, CCL2, CD97, COL13A1, COL14A1, COL15A1, COL7A1, CREG1, CSF1, CST3, CTSL1, CXCL3, DCN, DKK2, DPP4, DPT, ECM1, F10, FGF2, FGF7, GDF5, GPX3, GRN, HBEGF, HLA-C, HMOX1, HSD17B11, HTRA1, ICAM1, IL11, IL15RA, IL1RAP, IL1RL1, IL6, IL8, ITIH2, LIF, LY96, MAN2B2, MFAP4, MUC3A, NID1, NPC2, OLFML2A, PDGFA, PDGFD, PLAUR, PTGDS, PTN, SCPEP1, SECTM1, SEPP1, SERPINB2, SOD3, SULF1, SVEP1, THBD, TNFAIP2, TNFRSF11B, TNFRSF1B, TNFSF4, TNXB, VEGFA	673	extracellular region
GO:0044421	1.097e-10	12.08	42 ANGPTL2, ANGPTL4, APOD, CCL2, COL13A1, COL14A1, COL15A1, COL7A1, CSF1, CST3, CXCL3, DCN, DKK2, DPT, ECM1, FGF2, GDF5, GPX3, GRN, HBEGF, HMOX1, HTRA1, ICAM1, IL11, IL6, IL8, LIF, MFAP4, NID1, OLFML2A, PDGFA, PTN, SECTM1, SEPP1, SOD3, SULF1, THBD, TNFAIP2, TNFRSF11B, TNFSF4, TNXB, VEGFA	376	extracellular region part
GO:0005615	1.059e-08	7.613	30 ANGPTL2, ANGPTL4, APOD, CCL2, CSF1, CST3, CXCL3, DKK2, FGF2, GDF5, GPX3, GRN, HBEGF, HMOX1, HTRA1, ICAM1, IL11, IL6, IL8, LIF, PDGFA, PTN, SECTM1, SEPP1, SOD3, SULF1, THBD, TNFAIP2, TNFSF4, VEGFA	237	extracellular space
GO:0005886	2.490e-03	45.26	70 ADRA2A, AJAP1, AQP1, ASAP2, BDKRB1, CADPS2, CCRL1, CD55, CD97, CDC42SE1, CLEC2B, COL13A1, CSF1, DDX3Y, DGKD, DPP4, EPHB3, F10, F3, GAP43, GEM, GPNMB, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HTR2A, HTR2B, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6, ITPR3, KCNMB4, KCNN4, LGR4, LY96, LYN, MAGI2, NPC1, PKP2, PLAUR, PMEPA1, PPAP2A, PPL, PTPRN, RALGPS2, RAPGEF2, RGS3, SCARB2, SECTM1, SETD3, SH2B2, SHB, SLC19A2, SLC4A5, SPRED2, SPRY2, SPRY4, STOM, THBD, TM2D1, TNFRSF14, TNFRSF1B, TNFSF4, TNS3	1409	plasma membrane
GO:0042612	2.993e-03	0.4818	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	15	MHC class I protein complex
GO:0042611	1.635e-02	0.7067	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	22	MHC protein complex
GO:0031012	2.082e-02	5.236	14 ANGPTL4, COL13A1, COL14A1, COL15A1, COL7A1, DCN, DPT, ECM1, MFAP4, NID1, OLFML2A, TNFRSF11B, TNXB, VEGFA	163	extracellular matrix
GO:0005887	2.515e-02	17.19	31 ADRA2A, AQP1, BDKRB1, CCRL1, CD55, CD97, CLEC2B, EPHB3, GPNMB, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HTR2A, HTR2B, ICAM1, IL1RAP, IL6, KCNMB4, KCNN4, NPC1, PPAP2A, PTPRN, RAPGEF2, SCARB2, STOM, THBD, TM2D1, TNFRSF14, TNFSF4	535	integral to plasma membrane
GO:0044459	2.614e-02	27.46	44 ADRA2A, AJAP1, AQP1, BDKRB1, CADPS2, CCRL1, CD55, CD97, CLEC2B, DPP4, EPHB3, GAP43, GPNMB, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6, ITPR3, KCNMB4, KCNN4, MAGI2, NPC1, PKP2, PPAP2A, PPL, PTPRN, RAPGEF2, SCARB2, SLC4A5, STOM, THBD, TM2D1, TNFRSF14, TNFSF4, TNS3	855	plasma membrane part
GO:0031226	2.765e-02	17.31	31 ADRA2A, AQP1, BDKRB1, CCRL1, CD55, CD97, CLEC2B, EPHB3, GPNMB, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HTR2A, HTR2B, ICAM1, IL1RAP, IL6, KCNMB4, KCNN4, NPC1, PPAP2A, PTPRN, RAPGEF2, SCARB2, STOM, THBD, TM2D1, TNFRSF14, TNFSF4	539	intrinsic to plasma membrane
GO:0016020	3.048e-02	100.1	124 ACSL1, ADRA2A, AJAP1, ANO1, AQP1, ASAP2, ATP13A3, B4GALT5, B4GALT6, BDKRB1, C9orf167, CADPS2, CCRL1, CD302, CD55, CD97, CDC42SE1, CLEC2B, CLEC7A, COL13A1, CSF1, CSGALNACT2, CYP51A1, DDX3Y, DGKD, DNAJC1, DOCK9, DPP4, EPHB3, ERAP2, F10, F3, FADS3, FNDC3A, GAP43, GEM, GNPTAB, GPNMB, GPR37, HBEGF, HK2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HTR2A, HTR2B, ICAM1, IFITM1, IL15RA, IL1RAP, IL1RL1, IL6, ITPR3, KCNMB4, KCNN4, KIAA0247, KIAA1644, LEPROT, LGR4, LHFP, LMBRD1, LRIG1, LRRC15, LY96, LYN, MAGI2, MAN1C1, MAP3K7IP2, MUC3A, NID1, NINJ1, NPC1, NR3C1, OLFML2A, OSTM1, PDGFA, PDGFD, PHLDA1, PKP2, PLAUR, PLSCR4, PMEPA1, PPAP2A, PPL, PTGDS, PTPRN, RALGPS2, RAPGEF2, RGS3, SCARB2, SECTM1, SEMA5A, SETD3, SH2B2, SHB, SLC19A2, SLC39A8, SLC4A5, SLCO3A1, SOD2, SPRED2, SPRY2, SPRY4, SQRDL, STOM, SVEP1, TEX2, THBD, TM2D1, TM6SF1, TMBIM4, TMEM158, TMEM41B, TNFRSF14, TNFRSF1B, TNFSF4, TNS3, TOM1, TPST1, VEGFA, WTAP, YRDC	3116	membrane
GO:0005581	3.176e-02	0.8352	5 COL13A1, COL14A1, COL15A1, COL7A1, TNXB	26	collagen
GO:0005578	3.178e-02	4.915	13 ANGPTL4, COL13A1, COL14A1, COL15A1, COL7A1, DCN, DPT, ECM1, MFAP4, NID1, TNFRSF11B, TNXB, VEGFA	153	proteinaceous extracellular matrix

Id	Pvalue	ExpCount	Count	Size	Term
GO:0004871	9.767e-05	25.16	52 ADRA2A, BDKRB1, CBLB, CCL2, CCRL1, CD97, CLEC7A, ECM1, EPHB3, GNAL, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HMOX1, HTR2A, HTR2B, ICAM1, IFITM1, IL15RA, IL1RAP, IL1RL1, ITPR3, LGR4, LY96, LYN, MAP3K4, NPC1, NR3C1, NR4A3, PLAUR, PPARD, PTPRN, RAPGEF2, RGS2, RGS3, SCARB2, SECTM1, SEMA5A, SH2B2, SHB, SOCS2, THBD, TM2D1, TNFRSF11B, TNFRSF14, TNFRSF1B, TP53BP2, TRAF3	780	signal transducer activity
GO:0060089	9.767e-05	25.16	52 ADRA2A, BDKRB1, CBLB, CCL2, CCRL1, CD97, CLEC7A, ECM1, EPHB3, GNAL, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HMOX1, HTR2A, HTR2B, ICAM1, IFITM1, IL15RA, IL1RAP, IL1RL1, ITPR3, LGR4, LY96, LYN, MAP3K4, NPC1, NR3C1, NR4A3, PLAUR, PPARD, PTPRN, RAPGEF2, RGS2, RGS3, SCARB2, SECTM1, SEMA5A, SH2B2, SHB, SOCS2, THBD, TM2D1, TNFRSF11B, TNFRSF14, TNFRSF1B, TP53BP2, TRAF3	780	molecular transducer activity
GO:0005125	1.454e-04	2.29	13 CCL2, CSF1, GDF5, GRN, IL11, IL6, IL8, LIF, NAMPT, SECTM1, TNFRSF11B, TNFSF4, VEGFA	71	cytokine activity
GO:0032393	1.002e-03	0.2903	5 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F	9	MHC class I receptor activity
GO:0008083	1.431e-03	2.935	13 CSF1, FGF2, FGF7, GDF5, GRN, HBEGF, IL11, IL6, LIF, PDGFA, PDGFD, PTN, VEGFA	91	growth factor activity
GO:0004872	3.929e-03	16.74	35 ADRA2A, BDKRB1, CCRL1, CD97, CLEC7A, EPHB3, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HTR2A, HTR2B, ICAM1, IL15RA, IL1RAP, IL1RL1, ITPR3, LGR4, LY96, NPC1, NR3C1, NR4A3, PLAUR, PPARD, PTPRN, SCARB2, SEMA5A, THBD, TM2D1, TNFRSF11B, TNFRSF14, TNFRSF1B	519	receptor activity
GO:0004888	6.513e-03	10.45	25 ADRA2A, BDKRB1, CCRL1, CD97, EPHB3, GPR37, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HTR2A, HTR2B, ICAM1, IL15RA, IL1RAP, IL1RL1, LGR4, NPC1, PTPRN, SEMA5A, THBD, TM2D1, TNFRSF14, TNFRSF1B	324	transmembrane receptor activity
GO:0005102	1.109e-02	12.9	28 ANGPTL2, ANGPTL4, CCL2, CLEC7A, CSF1, FGF2, FGF7, GDF5, GPNMB, GRN, HBEGF, ICAM1, IL11, IL6, IL8, LIF, MFAP4, MTSS1, NAMPT, PDGFA, PDGFD, PSMB8, PTN, SECTM1, SOCS2, TNFRSF11B, TNFSF4, VEGFA	400	receptor binding
GO:0008236	1.729e-02	2	9 C1R, C1S, CTSA, DPP4, F10, HTRA1, SCPEP1, SERPINB2, TPP1	62	serine-type peptidase activity
GO:0017171	1.729e-02	2	9 C1R, C1S, CTSA, DPP4, F10, HTRA1, SCPEP1, SERPINB2, TPP1	62	serine hydrolase activity
GO:0030246	2.664e-02	4.194	13 CD302, CLEC2B, CLEC7A, COL13A1, FGF2, GAA, GPNMB, HBEGF, MAN2B1, MAN2B2, PTN, SOD3, VEGFA	130	carbohydrate binding
GO:0008201	3.873e-02	1.419	7 COL13A1, FGF2, GPNMB, HBEGF, PTN, SOD3, VEGFA	44	heparin binding

Id	Pvalue	ExpCount	Count	Size	Term
04060	1.183e-03	4.578	16 CCL2, CSF1, CXCL3, GDF5, IL11, IL15RA, IL1RAP, IL6, IL8, LIF, PDGFA, TNFRSF11B, TNFRSF14, TNFRSF1B, TNFSF4, VEGFA	115	Cytokine-cytokine receptor interaction
04610	3.604e-03	1.314	8 BDKRB1, C1R, C1S, CD55, F10, F3, PLAUR, THBD	33	Complement and coagulation cascades
05332	1.036e-02	0.8359	6 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, IL6	21	Graft-versus-host disease
04630	1.095e-02	3.463	12 CBLB, CCND2, IL11, IL15RA, IL6, LIF, PIAS4, PIK3CD, SOCS2, SPRED2, SPRY2, SPRY4	87	Jak-STAT signaling pathway
04940	2.690e-02	1.035	6 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, PTPRN	26	Type I diabetes mellitus

No enriched terms

No enriched terms

Entrez genes

ABLIM3actin binding LIM protein family, member 3 (205730_s_at), score: -0.26 ACSL1acyl-CoA synthetase long-chain family member 1 (201963_at), score: -0.26 ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide (209612_s_at), score: -0.36 ADRA2Aadrenergic, alpha-2A-, receptor (209869_at), score: -0.47 AEBP1AE binding protein 1 (201792_at), score: -0.25 AJAP1adherens junctions associated protein 1 (206460_at), score: -0.32 AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (209160_at), score: -0.26 ANGPTL2angiopoietin-like 2 (213004_at), score: -0.23 ANGPTL4angiopoietin-like 4 (221009_s_at), score: -0.43 ANO1anoctamin 1, calcium activated chloride channel (218804_at), score: -0.33 APODapolipoprotein D (201525_at), score: -0.43 AQP1aquaporin 1 (Colton blood group) (209047_at), score: -0.32 ARID5AAT rich interactive domain 5A (MRF1-like) (213138_at), score: -0.23 ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (206414_s_at), score: -0.33 ATP13A3ATPase type 13A3 (219558_at), score: -0.24 B4GALT5UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (221484_at), score: -0.3 B4GALT6UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 (206233_at), score: 0.78 BDKRB1bradykinin receptor B1 (207510_at), score: -0.24 BHLHE40basic helix-loop-helix family, member e40 (201170_s_at), score: -0.24 C11orf20chromosome 11 open reading frame 20 (219883_at), score: 0.78 C17orf91chromosome 17 open reading frame 91 (214696_at), score: -0.29 C1Rcomplement component 1, r subcomponent (212067_s_at), score: -0.47 C1Scomplement component 1, s subcomponent (208747_s_at), score: -0.33 C9orf167chromosome 9 open reading frame 167 (219620_x_at), score: -0.24 CADPS2Ca++-dependent secretion activator 2 (219572_at), score: -0.26 CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (211368_s_at), score: -0.28 CASP4caspase 4, apoptosis-related cysteine peptidase (209310_s_at), score: -0.28 CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b (209682_at), score: -0.31 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: -0.33 CCND2cyclin D2 (200953_s_at), score: 0.74 CCRL1chemokine (C-C motif) receptor-like 1 (220351_at), score: -0.54 CD302CD302 molecule (203799_at), score: -0.4 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: -0.31 CD97CD97 molecule (202910_s_at), score: -0.29 CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae) (208022_s_at), score: -0.23 CDC42SE1CDC42 small effector 1 (218157_x_at), score: -0.39 CLEC2BC-type lectin domain family 2, member B (209732_at), score: -0.45 CLEC7AC-type lectin domain family 7, member A (221698_s_at), score: 0.83 COL13A1collagen, type XIII, alpha 1 (211343_s_at), score: -0.24 COL14A1collagen, type XIV, alpha 1 (212865_s_at), score: -0.35 COL15A1collagen, type XV, alpha 1 (203477_at), score: -0.6 COL7A1collagen, type VII, alpha 1 (217312_s_at), score: -0.22 CREG1cellular repressor of E1A-stimulated genes 1 (201200_at), score: -0.51 CSF1colony stimulating factor 1 (macrophage) (209716_at), score: -0.32 CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 2 (222235_s_at), score: -0.35 CST3cystatin C (201360_at), score: -0.31 CTSAcathepsin A (200661_at), score: -0.25 CTSL1cathepsin L1 (202087_s_at), score: -0.26 CTTNBP2NLCTTNBP2 N-terminal like (214731_at), score: 0.75 CXCL3chemokine (C-X-C motif) ligand 3 (207850_at), score: -0.31 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: -0.23 DCNdecorin (211896_s_at), score: -0.35 DDX3YDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked (205000_at), score: -0.33 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: -0.3 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: -0.61 DNAJC1DnaJ (Hsp40) homolog, subfamily C, member 1 (218409_s_at), score: -0.23 DOCK9dedicator of cytokinesis 9 (212538_at), score: -0.26 DPP4dipeptidyl-peptidase 4 (211478_s_at), score: -0.49 DPTdermatopontin (213068_at), score: -0.35 DUSP14dual specificity phosphatase 14 (203367_at), score: -0.3 DUSP3dual specificity phosphatase 3 (201536_at), score: -0.28 ECM1extracellular matrix protein 1 (209365_s_at), score: -0.45 EGLN2egl nine homolog 2 (C. elegans) (220956_s_at), score: 0.75 EGR2early growth response 2 (Krox-20 homolog, Drosophila) (205249_at), score: -0.3 EGR3early growth response 3 (206115_at), score: -0.35 EIF1AYeukaryotic translation initiation factor 1A, Y-linked (204409_s_at), score: -0.24 EPHB3EPH receptor B3 (1438_at), score: 0.8 ERAP2endoplasmic reticulum aminopeptidase 2 (219759_at), score: -0.23 EXD3exonuclease 3'-5' domain containing 3 (220838_at), score: 0.8 F10coagulation factor X (205620_at), score: -0.44 F3coagulation factor III (thromboplastin, tissue factor) (204363_at), score: -0.44 FADS3fatty acid desaturase 3 (216080_s_at), score: -0.24 FAM13Bfamily with sequence similarity 13, member B (218518_at), score: -0.23 FGF2fibroblast growth factor 2 (basic) (204421_s_at), score: -0.29 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: -0.41 FHOD1formin homology 2 domain containing 1 (218530_at), score: -0.24 FLGfilaggrin (215704_at), score: 0.95 FLJ10404hypothetical protein FLJ10404 (218920_at), score: 0.76 FNDC3Afibronectin type III domain containing 3A (202304_at), score: -0.29 FOSBFBJ murine osteosarcoma viral oncogene homolog B (202768_at), score: -0.38 GAAglucosidase, alpha; acid (202812_at), score: -0.24 GADD45Agrowth arrest and DNA-damage-inducible, alpha (203725_at), score: -0.22 GAP43growth associated protein 43 (204471_at), score: 1 GDF5growth differentiation factor 5 (206614_at), score: 0.83 GEMGTP binding protein overexpressed in skeletal muscle (204472_at), score: -0.3 GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (206355_at), score: 0.75 GNPTABN-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (212959_s_at), score: -0.27 GPNMBglycoprotein (transmembrane) nmb (201141_at), score: -0.81 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: -0.27 GPX3glutathione peroxidase 3 (plasma) (214091_s_at), score: -0.25 GRAMD3GRAM domain containing 3 (218706_s_at), score: -0.24 GRNgranulin (211284_s_at), score: -0.4 GSTT1glutathione S-transferase theta 1 (203815_at), score: -0.28 HBEGFheparin-binding EGF-like growth factor (203821_at), score: -0.33 HHEXhematopoietically expressed homeobox (215933_s_at), score: -0.24 HK2hexokinase 2 (202934_at), score: -0.56 HLA-Amajor histocompatibility complex, class I, A (213932_x_at), score: -0.37 HLA-Amajor histocompatibility complex, class I, A (217436_x_at), score: -0.36 HLA-Bmajor histocompatibility complex, class I, B (211911_x_at), score: -0.37 HLA-Cmajor histocompatibility complex, class I, C (211799_x_at), score: -0.47 HLA-Emajor histocompatibility complex, class I, E (200904_at), score: -0.5 HLA-Fmajor histocompatibility complex, class I, F (204806_x_at), score: -0.42 HMGN1high-mobility group nucleosome binding domain 1 (200944_s_at), score: 0.75 HMOX1heme oxygenase (decycling) 1 (203665_at), score: -0.42 HOXB6homeobox B6 (205366_s_at), score: -0.27 HOXB7homeobox B7 (204779_s_at), score: -0.24 HOXC10homeobox C10 (218959_at), score: -0.34 HOXD11homeobox D11 (214604_at), score: 0.86 HPCAL1hippocalcin-like 1 (205462_s_at), score: -0.36 HSD17B11hydroxysteroid (17-beta) dehydrogenase 11 (217989_at), score: -0.26 HSPB7heat shock 27kDa protein family, member 7 (cardiovascular) (218934_s_at), score: -0.38 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: -0.34 HTR2B5-hydroxytryptamine (serotonin) receptor 2B (206638_at), score: -0.28 HTRA1HtrA serine peptidase 1 (201185_at), score: -0.31 ICAM1intercellular adhesion molecule 1 (202638_s_at), score: -0.25 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: -0.29 IDUAiduronidase, alpha-L- (205059_s_at), score: -0.25 IFITM1interferon induced transmembrane protein 1 (9-27) (214022_s_at), score: -0.39 IL11interleukin 11 (206924_at), score: -0.24 IL15RAinterleukin 15 receptor, alpha (207375_s_at), score: -0.26 IL1RAPinterleukin 1 receptor accessory protein (205227_at), score: -0.35 IL1RL1interleukin 1 receptor-like 1 (207526_s_at), score: -0.74 IL6interleukin 6 (interferon, beta 2) (205207_at), score: -0.56 IL8interleukin 8 (211506_s_at), score: -0.46 ITIH2inter-alpha (globulin) inhibitor H2 (204987_at), score: 0.82 ITPR3inositol 1,4,5-triphosphate receptor, type 3 (201189_s_at), score: -0.36 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: -0.32 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (221778_at), score: -0.38 JMJD3jumonji domain containing 3, histone lysine demethylase (213146_at), score: -0.4 KANK1KN motif and ankyrin repeat domains 1 (213005_s_at), score: -0.25 KCNMB4potassium large conductance calcium-activated channel, subfamily M, beta member 4 (219287_at), score: 0.74 KCNN4potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (204401_at), score: -0.25 KHDRBS3KH domain containing, RNA binding, signal transduction associated 3 (209781_s_at), score: -0.35 KIAA0247KIAA0247 (202181_at), score: -0.22 KIAA1644KIAA1644 (52837_at), score: -0.42 KLHL21kelch-like 21 (Drosophila) (203068_at), score: -0.28 KLHL26kelch-like 26 (Drosophila) (219354_at), score: -0.22 LEPROTleptin receptor overlapping transcript (202378_s_at), score: -0.24 LGR4leucine-rich repeat-containing G protein-coupled receptor 4 (218326_s_at), score: 0.82 LHFPlipoma HMGIC fusion partner (218656_s_at), score: -0.49 LIFleukemia inhibitory factor (cholinergic differentiation factor) (205266_at), score: -0.24 LMBRD1LMBR1 domain containing 1 (218191_s_at), score: -0.43 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: -0.37 LOC100128809similar to hCG2045829 (215707_s_at), score: -0.23 LOC286434hypothetical protein LOC286434 (222196_at), score: 0.87 LOC730227hypothetical protein LOC730227 (215756_at), score: 0.74 LRIG1leucine-rich repeats and immunoglobulin-like domains 1 (211596_s_at), score: -0.26 LRRC15leucine rich repeat containing 15 (213909_at), score: -0.31 LY96lymphocyte antigen 96 (206584_at), score: -0.47 LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog (202625_at), score: -0.23 MAFv-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) (209348_s_at), score: -0.23 MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 (209737_at), score: -0.25 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: -0.43 MAN2B1mannosidase, alpha, class 2B, member 1 (209166_s_at), score: -0.39 MAN2B2mannosidase, alpha, class 2B, member 2 (214703_s_at), score: -0.23 MAP2K3mitogen-activated protein kinase kinase 3 (207667_s_at), score: -0.38 MAP3K4mitogen-activated protein kinase kinase kinase 4 (216199_s_at), score: -0.23 MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (210284_s_at), score: -0.24 MEIS1Meis homeobox 1 (204069_at), score: -0.25 MEIS3P1Meis homeobox 3 pseudogene 1 (214077_x_at), score: -0.35 MEOX1mesenchyme homeobox 1 (205619_s_at), score: 0.79 MFAP4microfibrillar-associated protein 4 (212713_at), score: -0.36 MTSS1metastasis suppressor 1 (203037_s_at), score: -0.3 MUC3Amucin 3A, cell surface associated (217117_x_at), score: 0.75 MYO1Dmyosin ID (212338_at), score: -0.45 NAMPTnicotinamide phosphoribosyltransferase (217738_at), score: -0.46 NET1neuroepithelial cell transforming 1 (201830_s_at), score: -0.23 NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (210162_s_at), score: -0.48 NFIBnuclear factor I/B (209290_s_at), score: 0.77 NFIL3nuclear factor, interleukin 3 regulated (203574_at), score: -0.38 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: -0.45 NID1nidogen 1 (202008_s_at), score: -0.32 NINJ1ninjurin 1 (203045_at), score: -0.33 NKX3-1NK3 homeobox 1 (209706_at), score: -0.24 NOVA1neuro-oncological ventral antigen 1 (205794_s_at), score: 0.77 NPnucleoside phosphorylase (201695_s_at), score: -0.26 NPC1Niemann-Pick disease, type C1 (202679_at), score: -0.4 NPC2Niemann-Pick disease, type C2 (200701_at), score: -0.54 NPTX1neuronal pentraxin I (204684_at), score: -0.27 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: -0.24 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: -0.47 NT5DC25'-nucleotidase domain containing 2 (218051_s_at), score: 0.81 OLFML2Aolfactomedin-like 2A (213075_at), score: -0.34 OSTM1osteopetrosis associated transmembrane protein 1 (218196_at), score: -0.34 PDGFAplatelet-derived growth factor alpha polypeptide (205463_s_at), score: -0.29 PDGFDplatelet derived growth factor D (219304_s_at), score: -0.43 PHLDA1pleckstrin homology-like domain, family A, member 1 (217997_at), score: -0.24 PIAS4protein inhibitor of activated STAT, 4 (212881_at), score: 0.75 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (203879_at), score: -0.35 PKP2plakophilin 2 (207717_s_at), score: -0.31 PLAURplasminogen activator, urokinase receptor (211924_s_at), score: -0.24 PLSCR4phospholipid scramblase 4 (218901_at), score: -0.25 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: -0.51 PPAP2Aphosphatidic acid phosphatase type 2A (209147_s_at), score: -0.37 PPARDperoxisome proliferator-activated receptor delta (37152_at), score: -0.44 PPLperiplakin (203407_at), score: -0.41 PSG4pregnancy specific beta-1-glycoprotein 4 (208191_x_at), score: -0.25 PSMB8proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (209040_s_at), score: -0.23 PTGDSprostaglandin D2 synthase 21kDa (brain) (212187_x_at), score: -0.41 PTNpleiotrophin (209466_x_at), score: -0.24 PTPRNprotein tyrosine phosphatase, receptor type, N (204945_at), score: 0.79 RABGGTBRab geranylgeranyltransferase, beta subunit (209180_at), score: -0.23 RALGPS2Ral GEF with PH domain and SH3 binding motif 2 (220338_at), score: 0.82 RAPGEF2Rap guanine nucleotide exchange factor (GEF) 2 (203097_s_at), score: -0.39 RCAN2regulator of calcineurin 2 (203498_at), score: -0.52 RCL1RNA terminal phosphate cyclase-like 1 (218544_s_at), score: -0.28 RGS2regulator of G-protein signaling 2, 24kDa (202388_at), score: -0.23 RGS3regulator of G-protein signaling 3 (203823_at), score: -0.44 RPS4Y1ribosomal protein S4, Y-linked 1 (201909_at), score: -0.44 RRADRas-related associated with diabetes (204802_at), score: -0.61 RUFY2RUN and FYVE domain containing 2 (219957_at), score: 0.74 RUNX1runt-related transcription factor 1 (209360_s_at), score: -0.31 SAT1spermidine/spermine N1-acetyltransferase 1 (213988_s_at), score: -0.27 SCARB2scavenger receptor class B, member 2 (201647_s_at), score: -0.24 SCPEP1serine carboxypeptidase 1 (218217_at), score: -0.31 SECTM1secreted and transmembrane 1 (213716_s_at), score: -0.37 SEMA5Asema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (205405_at), score: -0.27 SEPP1selenoprotein P, plasma, 1 (201427_s_at), score: -0.34 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: -0.33 SETD3SET domain containing 3 (212465_at), score: -0.26 SFRS5splicing factor, arginine/serine-rich 5 (212266_s_at), score: -0.28 SH2B2SH2B adaptor protein 2 (205367_at), score: 0.78 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: -0.32 SIX1SIX homeobox 1 (205817_at), score: 0.79 SLC19A2solute carrier family 19 (thiamine transporter), member 2 (209681_at), score: -0.31 SLC39A8solute carrier family 39 (zinc transporter), member 8 (209267_s_at), score: -0.41 SLC4A5solute carrier family 4, sodium bicarbonate cotransporter, member 5 (204296_at), score: 0.75 SLCO3A1solute carrier organic anion transporter family, member 3A1 (219229_at), score: -0.27 SMOXspermine oxidase (210357_s_at), score: -0.27 SOCS2suppressor of cytokine signaling 2 (203373_at), score: -0.29 SOD2superoxide dismutase 2, mitochondrial (221477_s_at), score: -0.25 SOD3superoxide dismutase 3, extracellular (205236_x_at), score: -0.47 SOX11SRY (sex determining region Y)-box 11 (204914_s_at), score: 0.94 SOX4SRY (sex determining region Y)-box 4 (201417_at), score: -0.28 SPRED2sprouty-related, EVH1 domain containing 2 (212458_at), score: -0.27 SPRY2sprouty homolog 2 (Drosophila) (204011_at), score: -0.29 SPRY4sprouty homolog 4 (Drosophila) (221489_s_at), score: -0.33 SQRDLsulfide quinone reductase-like (yeast) (217995_at), score: -0.27 STK38Lserine/threonine kinase 38 like (212572_at), score: -0.28 STOMstomatin (201060_x_at), score: -0.28 SULF1sulfatase 1 (212353_at), score: -0.25 SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (213247_at), score: -0.46 TBX3T-box 3 (219682_s_at), score: -0.41 TEX2testis expressed 2 (218099_at), score: -0.28 THBDthrombomodulin (203887_s_at), score: -0.41 TIPARPTCDD-inducible poly(ADP-ribose) polymerase (212665_at), score: -0.23 TM2D1TM2 domain containing 1 (211703_s_at), score: -0.44 TM6SF1transmembrane 6 superfamily member 1 (219892_at), score: -0.25 TMBIM4transmembrane BAX inhibitor motif containing 4 (219206_x_at), score: -0.33 TMEM158transmembrane protein 158 (213338_at), score: -0.29 TMEM41Btransmembrane protein 41B (212623_at), score: -0.49 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (202510_s_at), score: -0.45 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (210260_s_at), score: -0.23 TNFRSF11Btumor necrosis factor receptor superfamily, member 11b (204933_s_at), score: -0.41 TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (209354_at), score: -0.22 TNFRSF1Btumor necrosis factor receptor superfamily, member 1B (203508_at), score: -0.24 TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (207426_s_at), score: -0.28 TNS3tensin 3 (217853_at), score: -0.34 TNXBtenascin XB (216333_x_at), score: -0.24 TOM1target of myb1 (chicken) (202807_s_at), score: -0.24 TP53BP2tumor protein p53 binding protein, 2 (203120_at), score: -0.3 TP53I11tumor protein p53 inducible protein 11 (214667_s_at), score: -0.28 TPP1tripeptidyl peptidase I (200742_s_at), score: -0.47 TPST1tyrosylprotein sulfotransferase 1 (204140_at), score: -0.38 TRAF3TNF receptor-associated factor 3 (221571_at), score: -0.24 TRAF3IP2TRAF3 interacting protein 2 (215411_s_at), score: -0.34 TRIB1tribbles homolog 1 (Drosophila) (202241_at), score: -0.36 TRIM22tripartite motif-containing 22 (213293_s_at), score: -0.3 TRIM62tripartite motif-containing 62 (219272_at), score: 0.74 USP22ubiquitin specific peptidase 22 (200083_at), score: 0.75 VEGFAvascular endothelial growth factor A (211527_x_at), score: -0.35 WTAPWilms tumor 1 associated protein (210285_x_at), score: -0.42 YRDCyrdC domain containing (E. coli) (218647_s_at), score: -0.26 ZBTB20zinc finger and BTB domain containing 20 (205383_s_at), score: -0.28 ZKSCAN3zinc finger with KRAB and SCAN domains 3 (211773_s_at), score: 0.79 ZMYM6zinc finger, MYM-type 6 (219924_s_at), score: -0.32 ZNF35zinc finger protein 35 (206096_at), score: -0.26 ZNF672zinc finger protein 672 (218068_s_at), score: -0.23

Non-Entrez genes

Unknown, score:

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
t21b 08-03.CEL	5	1	DS-CC	hgu133a	Down	DS-CC 5
t21d 08-03.CEL	7	1	DS-CC	hgu133a	Down	DS-CC 7
t21c 08-03.CEL	6	1	DS-CC	hgu133a	Down	DS-CC 6
5CTwin.CEL	5	2	DS-twin	hgu133plus2	Down	DS-twin 5
2Twin.CEL	2	2	DS-twin	hgu133plus2	none	DS-twin 2
6Twin.CEL	6	2	DS-twin	hgu133plus2	none	DS-twin 6
1Twin.CEL	1	2	DS-twin	hgu133plus2	Down	DS-twin 1