Previous module | Next module Module #935, TG: 2.2, TC: 2, 376 probes, 376 Entrez genes, 5 conditions

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Expression data for module #935

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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skeletal system development

The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

response to external stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cellular component organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component.

biological adhesion

The attachment of a cell or organism to a substrate or other organism.

extracellular matrix organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of an extracellular matrix.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

extracellular structure organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

collagen

Any of the various assemblies in which collagen chains form a left-handed triple helix; may assemble into higher order structures.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

proteinaceous extracellular matrix

A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.

fibrillar collagen

Any collagen polymer in which collagen triple helices associate to form fibrils.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

extracellular matrix

A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants).

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

I-kappaB/NF-kappaB complex

A protein complex containing an I-kappaB protein and one or more copies of an NF-kappaB protein; mediates regulation of NF-kappaB activity by I-kappaB.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

extracellular matrix part

Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

extracellular matrix part

Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

I-kappaB/NF-kappaB complex

A protein complex containing an I-kappaB protein and one or more copies of an NF-kappaB protein; mediates regulation of NF-kappaB activity by I-kappaB.

collagen

Any of the various assemblies in which collagen chains form a left-handed triple helix; may assemble into higher order structures.

Help | Hide | Top The GO tree — Molecular Function

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protein binding

Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

pattern binding

Interacting selectively with a repeating or polymeric structure, such as a polysaccharide or peptidoglycan.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

receptor binding

Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

carbohydrate binding

Interacting selectively with any carbohydrate.

cytokine receptor activity

Combining with a cytokine to initiate a change in cell activity.

interleukin-1 receptor activity

Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.

growth factor binding

Interacting selectively with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.

cytokine activity

Functions to control the survival, growth, differentiation and effector function of tissues and cells.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

glycosaminoglycan binding

Interacting selectively with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.

heparin binding

Interacting selectively with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha1-4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.

cytokine binding

Interacting selectively with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.

interleukin-1 binding

Interacting selectively with interleukin-1.

polysaccharide binding

Interacting selectively with any polysaccharide.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

polysaccharide binding

Interacting selectively with any polysaccharide.

interleukin-1 binding

Interacting selectively with interleukin-1.

interleukin-1 receptor activity

Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.

cytokine receptor activity

Combining with a cytokine to initiate a change in cell activity.

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04060 1.484e-03 5.219 17
115 Cytokine-cytokine receptor interaction
00010 6.323e-03 1.861 9
41 Glycolysis / Gluconeogenesis

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ABCA8ATP-binding cassette, sub-family A (ABC1), member 8 (204719_at), score: 0.35 ABI1abl-interactor 1 (209028_s_at), score: -0.34 ABLIM1actin binding LIM protein 1 (200965_s_at), score: 0.35 ABLIM3actin binding LIM protein family, member 3 (205730_s_at), score: -0.36 ACSL1acyl-CoA synthetase long-chain family member 1 (201963_at), score: -0.41 ACSL4acyl-CoA synthetase long-chain family member 4 (202422_s_at), score: -0.44 ACTR5ARP5 actin-related protein 5 homolog (yeast) (219623_at), score: 0.38 ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif, 1 (222162_s_at), score: 0.34 ADAMTS6ADAM metallopeptidase with thrombospondin type 1 motif, 6 (220866_at), score: 0.34 ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide (209612_s_at), score: -0.67 ADH5alcohol dehydrogenase 5 (class III), chi polypeptide (208848_at), score: -0.34 ADRA2Aadrenergic, alpha-2A-, receptor (209869_at), score: -0.43 AFF1AF4/FMR2 family, member 1 (201924_at), score: -0.34 AIPL1aryl hydrocarbon receptor interacting protein-like 1 (219977_at), score: 0.32 AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (204151_x_at), score: -0.3 AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (209160_at), score: -0.53 ALADaminolevulinate, delta-, dehydratase (218487_at), score: -0.36 ALAS1aminolevulinate, delta-, synthase 1 (205633_s_at), score: -0.31 AMD1adenosylmethionine decarboxylase 1 (201196_s_at), score: -0.31 ANGangiogenin, ribonuclease, RNase A family, 5 (213397_x_at), score: -0.3 ANO1anoctamin 1, calcium activated chloride channel (218804_at), score: -0.31 APBB1IPamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein (219994_at), score: -0.32 APODapolipoprotein D (201525_at), score: -0.78 ARFGAP1ADP-ribosylation factor GTPase activating protein 1 (217888_s_at), score: 0.36 ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (206414_s_at), score: -0.64 ASNSasparagine synthetase (205047_s_at), score: 0.4 ASPHD1aspartate beta-hydroxylase domain containing 1 (214993_at), score: 0.33 ATF1activating transcription factor 1 (222103_at), score: -0.33 ATF5activating transcription factor 5 (204999_s_at), score: -0.48 AUHAU RNA binding protein/enoyl-Coenzyme A hydratase (205052_at), score: -0.35 B4GALT5UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (221484_at), score: -0.31 B4GALT6UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 (206233_at), score: 0.52 BACE2beta-site APP-cleaving enzyme 2 (217867_x_at), score: 0.4 BAG1BCL2-associated athanogene (211475_s_at), score: -0.32 BCL11AB-cell CLL/lymphoma 11A (zinc finger protein) (219497_s_at), score: 0.37 BCL3B-cell CLL/lymphoma 3 (204908_s_at), score: -0.38 BEND5BEN domain containing 5 (219670_at), score: 0.35 BMP2bone morphogenetic protein 2 (205289_at), score: -0.32 BNC1basonuclin 1 (206581_at), score: -0.33 BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3 (201848_s_at), score: 0.45 BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like (221479_s_at), score: 0.37 BTN3A2butyrophilin, subfamily 3, member A2 (209846_s_at), score: -0.37 C13orf15chromosome 13 open reading frame 15 (218723_s_at), score: -0.44 C14orf104chromosome 14 open reading frame 104 (219166_at), score: -0.32 C16orf7chromosome 16 open reading frame 7 (205781_at), score: 0.38 C1DC1D nuclear receptor co-repressor (200056_s_at), score: -0.31 C1orf56chromosome 1 open reading frame 56 (221222_s_at), score: -0.33 C21orf2chromosome 21 open reading frame 2 (203996_s_at), score: 0.36 C22orf9chromosome 22 open reading frame 9 (217118_s_at), score: -0.4 C2CD2C2 calcium-dependent domain containing 2 (212875_s_at), score: -0.43 C6orf48chromosome 6 open reading frame 48 (220755_s_at), score: 0.32 C6orf66chromosome 6 open reading frame 66 (219006_at), score: -0.34 CAB39calcium binding protein 39 (217873_at), score: -0.41 CADM1cell adhesion molecule 1 (209031_at), score: 0.46 CAMK2N1calcium/calmodulin-dependent protein kinase II inhibitor 1 (218309_at), score: -0.34 CBX7chromobox homolog 7 (212914_at), score: -0.32 CCDC59coiled-coil domain containing 59 (218936_s_at), score: -0.34 CCND2cyclin D2 (200953_s_at), score: 0.8 CCRL1chemokine (C-C motif) receptor-like 1 (220351_at), score: -0.69 CD302CD302 molecule (203799_at), score: -0.46 CD40CD40 molecule, TNF receptor superfamily member 5 (35150_at), score: 0.36 CD97CD97 molecule (202910_s_at), score: -0.36 CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae) (208022_s_at), score: -0.34 CDC42SE1CDC42 small effector 1 (218157_x_at), score: -0.41 CDH13cadherin 13, H-cadherin (heart) (204726_at), score: -0.33 CDH18cadherin 18, type 2 (206280_at), score: 0.59 CDYLchromodomain protein, Y-like (203100_s_at), score: -0.33 CEBPBCCAAT/enhancer binding protein (C/EBP), beta (212501_at), score: -0.32 CEBPZCCAAT/enhancer binding protein (C/EBP), zeta (203341_at), score: -0.46 CHD1chromodomain helicase DNA binding protein 1 (204258_at), score: -0.3 CHORDC1cysteine and histidine-rich domain (CHORD)-containing 1 (218566_s_at), score: -0.43 CHPFchondroitin polymerizing factor (202175_at), score: 0.38 CLDN11claudin 11 (206908_s_at), score: 0.37 CLEC2BC-type lectin domain family 2, member B (209732_at), score: -0.43 CLEC7AC-type lectin domain family 7, member A (221698_s_at), score: 0.37 CNN3calponin 3, acidic (201445_at), score: 0.43 COL11A1collagen, type XI, alpha 1 (37892_at), score: 0.53 COL13A1collagen, type XIII, alpha 1 (211343_s_at), score: -0.3 COL14A1collagen, type XIV, alpha 1 (212865_s_at), score: -0.62 COL1A1collagen, type I, alpha 1 (217430_x_at), score: 0.33 COL5A1collagen, type V, alpha 1 (212488_at), score: 0.37 COL5A2collagen, type V, alpha 2 (221730_at), score: 0.38 CPA4carboxypeptidase A4 (205832_at), score: 0.35 CPNE3copine III (202118_s_at), score: -0.4 CREG1cellular repressor of E1A-stimulated genes 1 (201200_at), score: -0.37 CSF1colony stimulating factor 1 (macrophage) (209716_at), score: -0.5 CSRP2cysteine and glycine-rich protein 2 (211126_s_at), score: 0.46 CTSBcathepsin B (213274_s_at), score: -0.5 CTSL1cathepsin L1 (202087_s_at), score: -0.55 CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (204470_at), score: -0.42 CXCL2chemokine (C-X-C motif) ligand 2 (209774_x_at), score: -0.33 CXCL3chemokine (C-X-C motif) ligand 3 (207850_at), score: -0.4 DHRS3dehydrogenase/reductase (SDR family) member 3 (202481_at), score: 0.38 DKFZP586H2123regeneration associated muscle protease (213661_at), score: 0.32 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: -0.69 DMWDdystrophia myotonica, WD repeat containing (33768_at), score: 0.36 DNTTIP2deoxynucleotidyltransferase, terminal, interacting protein 2 (202776_at), score: -0.38 DOCK10dedicator of cytokinesis 10 (219279_at), score: -0.3 DOCK4dedicator of cytokinesis 4 (205003_at), score: -0.37 DPP4dipeptidyl-peptidase 4 (211478_s_at), score: -0.47 DPTdermatopontin (213068_at), score: -0.42 DPYDdihydropyrimidine dehydrogenase (204646_at), score: -0.37 DPYSL3dihydropyrimidinase-like 3 (201431_s_at), score: -0.35 DSPdesmoplakin (200606_at), score: 0.51 DUSP14dual specificity phosphatase 14 (203367_at), score: -0.38 ECM1extracellular matrix protein 1 (209365_s_at), score: -0.34 ECM2extracellular matrix protein 2, female organ and adipocyte specific (206101_at), score: -0.34 EDARectodysplasin A receptor (220048_at), score: 0.38 EDIL3EGF-like repeats and discoidin I-like domains 3 (207379_at), score: 0.51 EGFL6EGF-like-domain, multiple 6 (219454_at), score: 0.37 EGFRepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (201983_s_at), score: -0.51 EGR1early growth response 1 (201694_s_at), score: 0.39 EIF4EBP1eukaryotic translation initiation factor 4E binding protein 1 (221539_at), score: 0.39 EIF5Aeukaryotic translation initiation factor 5A (201123_s_at), score: 0.58 ELK3ELK3, ETS-domain protein (SRF accessory protein 2) (221773_at), score: -0.39 EML1echinoderm microtubule associated protein like 1 (204797_s_at), score: -0.43 ENO2enolase 2 (gamma, neuronal) (201313_at), score: 0.36 EPHB3EPH receptor B3 (1438_at), score: 0.33 ERAP2endoplasmic reticulum aminopeptidase 2 (219759_at), score: -0.31 ETS2v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (201328_at), score: -0.41 F10coagulation factor X (205620_at), score: -0.37 F3coagulation factor III (thromboplastin, tissue factor) (204363_at), score: -0.44 FAM38Bfamily with sequence similarity 38, member B (219602_s_at), score: 0.52 FAM70Afamily with sequence similarity 70, member A (219895_at), score: 0.32 FBLN2fibulin 2 (203886_s_at), score: -0.32 FBN2fibrillin 2 (203184_at), score: 0.36 FEM1Bfem-1 homolog b (C. elegans) (212367_at), score: -0.35 FGF13fibroblast growth factor 13 (205110_s_at), score: -0.38 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: -0.3 FLGfilaggrin (215704_at), score: 1 FMODfibromodulin (202709_at), score: 0.51 FNDC3Afibronectin type III domain containing 3A (202304_at), score: -0.46 FOSv-fos FBJ murine osteosarcoma viral oncogene homolog (209189_at), score: 0.67 FOSL1FOS-like antigen 1 (204420_at), score: -0.46 GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 5 (206456_at), score: 0.35 GABRQgamma-aminobutyric acid (GABA) receptor, theta (220886_at), score: 0.33 GATAD2AGATA zinc finger domain containing 2A (218131_s_at), score: -0.32 GCC2GRIP and coiled-coil domain containing 2 (202832_at), score: -0.36 GCH1GTP cyclohydrolase 1 (204224_s_at), score: -0.34 GLSglutaminase (203159_at), score: 0.45 GNG11guanine nucleotide binding protein (G protein), gamma 11 (204115_at), score: -0.33 GOLGA8Agolgi autoantigen, golgin subfamily a, 8A (208798_x_at), score: 0.35 GOLSYNGolgi-localized protein (218692_at), score: 0.52 GPIglucose phosphate isomerase (208308_s_at), score: 0.34 GPNMBglycoprotein (transmembrane) nmb (201141_at), score: -0.37 GPRC5BG protein-coupled receptor, family C, group 5, member B (203632_s_at), score: -0.37 HAPLN1hyaluronan and proteoglycan link protein 1 (205523_at), score: 0.63 HK2hexokinase 2 (202934_at), score: -0.46 HMGN1high-mobility group nucleosome binding domain 1 (200944_s_at), score: 0.44 HOXB5homeobox B5 (205601_s_at), score: 0.35 HOXC10homeobox C10 (218959_at), score: -0.56 HOXC8homeobox C8 (221350_at), score: 0.46 HOXD11homeobox D11 (214604_at), score: 0.37 HPCAL1hippocalcin-like 1 (205462_s_at), score: -0.47 HSD17B11hydroxysteroid (17-beta) dehydrogenase 11 (217989_at), score: -0.44 HSPB7heat shock 27kDa protein family, member 7 (cardiovascular) (218934_s_at), score: -0.36 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: -0.34 IER2immediate early response 2 (202081_at), score: 0.34 IER5immediate early response 5 (218611_at), score: -0.37 IFITM1interferon induced transmembrane protein 1 (9-27) (214022_s_at), score: -0.39 IGFBP2insulin-like growth factor binding protein 2, 36kDa (202718_at), score: 0.39 IGFBP3insulin-like growth factor binding protein 3 (212143_s_at), score: 0.39 IGFBP7insulin-like growth factor binding protein 7 (201162_at), score: 0.46 IL15RAinterleukin 15 receptor, alpha (207375_s_at), score: -0.43 IL1R1interleukin 1 receptor, type I (202948_at), score: -0.32 IL1RAPinterleukin 1 receptor accessory protein (205227_at), score: -0.31 IL1RL1interleukin 1 receptor-like 1 (207526_s_at), score: -0.99 IL33interleukin 33 (209821_at), score: -0.43 IL6interleukin 6 (interferon, beta 2) (205207_at), score: -0.44 IL8interleukin 8 (211506_s_at), score: -0.38 INHBBinhibin, beta B (205258_at), score: 0.32 ITIH2inter-alpha (globulin) inhibitor H2 (204987_at), score: 0.33 ITM2Bintegral membrane protein 2B (217732_s_at), score: -0.34 ITPR3inositol 1,4,5-triphosphate receptor, type 3 (201189_s_at), score: -0.33 JAG2jagged 2 (32137_at), score: 0.39 JAM2junctional adhesion molecule 2 (219213_at), score: 0.81 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: -0.35 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (221778_at), score: -0.53 KANK1KN motif and ankyrin repeat domains 1 (213005_s_at), score: -0.42 KBTBD2kelch repeat and BTB (POZ) domain containing 2 (212447_at), score: -0.33 KCNMB4potassium large conductance calcium-activated channel, subfamily M, beta member 4 (219287_at), score: 0.42 KHDRBS3KH domain containing, RNA binding, signal transduction associated 3 (209781_s_at), score: -0.36 KIAA1199KIAA1199 (212942_s_at), score: 0.37 KIAA1644KIAA1644 (52837_at), score: -0.58 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: 0.32 KLF10Kruppel-like factor 10 (202393_s_at), score: -0.33 KLF2Kruppel-like factor 2 (lung) (219371_s_at), score: 0.33 L3MBTLl(3)mbt-like (Drosophila) (210306_at), score: 0.32 LGALS3lectin, galactoside-binding, soluble, 3 (208949_s_at), score: -0.39 LGR4leucine-rich repeat-containing G protein-coupled receptor 4 (218326_s_at), score: 0.5 LHFPlipoma HMGIC fusion partner (218656_s_at), score: -0.64 LOC220594TL132 protein (213510_x_at), score: -0.3 LOC286434hypothetical protein LOC286434 (222196_at), score: 0.41 LOC440354PI-3-kinase-related kinase SMG-1 pseudogene (210396_s_at), score: -0.34 LOXlysyl oxidase (213640_s_at), score: 0.49 LOXL2lysyl oxidase-like 2 (202997_s_at), score: 0.67 LPHN1latrophilin 1 (203488_at), score: 0.34 LPHN2latrophilin 2 (206953_s_at), score: 0.33 LPXNleupaxin (216250_s_at), score: -0.31 LRP2low density lipoprotein-related protein 2 (205710_at), score: 0.32 LRRC15leucine rich repeat containing 15 (213909_at), score: -0.36 LXNlatexin (218729_at), score: 0.34 LY96lymphocyte antigen 96 (206584_at), score: -0.5 MAN1A1mannosidase, alpha, class 1A, member 1 (221760_at), score: -0.4 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: -0.46 MAN2B1mannosidase, alpha, class 2B, member 1 (209166_s_at), score: -0.38 MARCH7membrane-associated ring finger (C3HC4) 7 (202654_x_at), score: -0.35 MBmyoglobin (204179_at), score: 0.31 MDKmidkine (neurite growth-promoting factor 2) (209035_at), score: 0.38 MEG3maternally expressed 3 (non-protein coding) (210794_s_at), score: 0.44 MEOX1mesenchyme homeobox 1 (205619_s_at), score: 0.45 MESTmesoderm specific transcript homolog (mouse) (202016_at), score: 0.55 MFAP3Lmicrofibrillar-associated protein 3-like (205442_at), score: 0.33 MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor) (217871_s_at), score: 0.36 MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 (211071_s_at), score: 0.35 MSTP9macrophage stimulating, pseudogene 9 (213382_at), score: 0.35 MSX1msh homeobox 1 (205932_s_at), score: -0.39 MTSS1metastasis suppressor 1 (203037_s_at), score: -0.35 MUC13mucin 13, cell surface associated (218687_s_at), score: 0.37 MUC3Amucin 3A, cell surface associated (217117_x_at), score: 0.38 MYO1Dmyosin ID (212338_at), score: -0.57 NAMPTnicotinamide phosphoribosyltransferase (217738_at), score: -0.46 NAV2neuron navigator 2 (218330_s_at), score: -0.45 NDST1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 (202607_at), score: 0.36 NFIBnuclear factor I/B (209290_s_at), score: 0.32 NFIL3nuclear factor, interleukin 3 regulated (203574_at), score: -0.4 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: -0.48 NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (207535_s_at), score: -0.33 NKIRAS2NFKB inhibitor interacting Ras-like 2 (218240_at), score: 0.32 NOP16NOP16 nucleolar protein homolog (yeast) (203023_at), score: -0.31 NPC1Niemann-Pick disease, type C1 (202679_at), score: -0.3 NPTX1neuronal pentraxin I (204684_at), score: -0.4 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: -0.39 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: -0.33 NRP1neuropilin 1 (212298_at), score: -0.33 NT5DC25'-nucleotidase domain containing 2 (218051_s_at), score: 0.41 NT5E5'-nucleotidase, ecto (CD73) (203939_at), score: -0.32 NUAK1NUAK family, SNF1-like kinase, 1 (204589_at), score: 0.36 NXT1NTF2-like export factor 1 (218708_at), score: -0.32 OCLMoculomedin (208274_at), score: 0.46 OLFML1olfactomedin-like 1 (217525_at), score: -0.49 OLFML2Aolfactomedin-like 2A (213075_at), score: -0.34 OPCMLopioid binding protein/cell adhesion molecule-like (214111_at), score: 0.37 OVOL2ovo-like 2 (Drosophila) (211778_s_at), score: 0.33 P4HA1prolyl 4-hydroxylase, alpha polypeptide I (207543_s_at), score: 0.61 PALMparalemmin (203859_s_at), score: 0.52 PAMpeptidylglycine alpha-amidating monooxygenase (214620_x_at), score: -0.44 PAPPA2pappalysin 2 (213332_at), score: 0.48 PCTK2PCTAIRE protein kinase 2 (221918_at), score: -0.39 PCYOX1prenylcysteine oxidase 1 (203803_at), score: -0.32 PDGFRLplatelet-derived growth factor receptor-like (205226_at), score: -0.35 PDLIM7PDZ and LIM domain 7 (enigma) (203370_s_at), score: 0.37 PDXKpyridoxal (pyridoxine, vitamin B6) kinase (202671_s_at), score: 0.35 PFKFB36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (202464_s_at), score: -0.42 PFKLphosphofructokinase, liver (201102_s_at), score: 0.64 PFN2profilin 2 (204992_s_at), score: 0.35 PGK1phosphoglycerate kinase 1 (217356_s_at), score: 0.37 PGM1phosphoglucomutase 1 (201968_s_at), score: 0.34 PHLDA1pleckstrin homology-like domain, family A, member 1 (217997_at), score: -0.47 PHLDA2pleckstrin homology-like domain, family A, member 2 (209803_s_at), score: -0.38 PLA2G4Cphospholipase A2, group IVC (cytosolic, calcium-independent) (209785_s_at), score: -0.34 PLD3phospholipase D family, member 3 (201050_at), score: 0.38 PLOD1procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 (200827_at), score: 0.38 PLOD2procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (202619_s_at), score: 0.42 PLXDC1plexin domain containing 1 (219700_at), score: 0.32 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: -0.35 PNMA1paraneoplastic antigen MA1 (218224_at), score: -0.31 PNRC2proline-rich nuclear receptor coactivator 2 (217779_s_at), score: -0.49 POFUT2protein O-fucosyltransferase 2 (209578_s_at), score: 0.37 PON1paraoxonase 1 (206344_at), score: 0.37 POSTNperiostin, osteoblast specific factor (210809_s_at), score: 0.6 PPAP2Aphosphatidic acid phosphatase type 2A (209147_s_at), score: -0.39 PPARDperoxisome proliferator-activated receptor delta (37152_at), score: -0.51 PPLperiplakin (203407_at), score: -0.7 PPP1R9Aprotein phosphatase 1, regulatory (inhibitor) subunit 9A (221088_s_at), score: 0.34 PRSS12protease, serine, 12 (neurotrypsin, motopsin) (205515_at), score: 0.37 PSAT1phosphoserine aminotransferase 1 (220892_s_at), score: 0.39 PSG4pregnancy specific beta-1-glycoprotein 4 (208191_x_at), score: -0.4 PSG7pregnancy specific beta-1-glycoprotein 7 (205602_x_at), score: -0.3 PSPHphosphoserine phosphatase (205048_s_at), score: -0.41 PTNpleiotrophin (209466_x_at), score: -0.37 PTPRDprotein tyrosine phosphatase, receptor type, D (214043_at), score: 0.35 PTPRNprotein tyrosine phosphatase, receptor type, N (204945_at), score: 0.33 PVRL3poliovirus receptor-related 3 (213325_at), score: -0.4 RAI14retinoic acid induced 14 (202052_s_at), score: 0.39 RALGPS2Ral GEF with PH domain and SH3 binding motif 2 (220338_at), score: 0.34 RAPGEF2Rap guanine nucleotide exchange factor (GEF) 2 (203097_s_at), score: -0.44 RASGRP1RAS guanyl releasing protein 1 (calcium and DAG-regulated) (205590_at), score: 0.47 RCAN2regulator of calcineurin 2 (203498_at), score: -0.59 RELv-rel reticuloendotheliosis viral oncogene homolog (avian) (206036_s_at), score: -0.3 RELBv-rel reticuloendotheliosis viral oncogene homolog B (205205_at), score: -0.42 RGS3regulator of G-protein signaling 3 (203823_at), score: -0.42 RNF126ring finger protein 126 (205748_s_at), score: -0.33 RNF187ring finger protein 187 (212155_at), score: 0.32 RP11-345P4.4similar to solute carrier family 35, member E2 (217122_s_at), score: 0.32 RPL13Aribosomal protein L13a (200715_x_at), score: -0.33 RRADRas-related associated with diabetes (204802_at), score: -0.55 SCML1sex comb on midleg-like 1 (Drosophila) (218793_s_at), score: -0.31 SCPEP1serine carboxypeptidase 1 (218217_at), score: -0.35 SCRG1scrapie responsive protein 1 (205475_at), score: 0.65 SDC2syndecan 2 (212154_at), score: 0.33 SECTM1secreted and transmembrane 1 (213716_s_at), score: -0.5 SELENBP1selenium binding protein 1 (214433_s_at), score: -0.37 SEPT11septin 11 (201308_s_at), score: 0.35 SFRP4secreted frizzled-related protein 4 (204051_s_at), score: 0.6 SFRS6splicing factor, arginine/serine-rich 6 (206108_s_at), score: -0.42 SH2B2SH2B adaptor protein 2 (205367_at), score: 0.38 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: -0.46 SIX1SIX homeobox 1 (205817_at), score: 0.33 SLC23A2solute carrier family 23 (nucleobase transporters), member 2 (209236_at), score: -0.33 SLC27A3solute carrier family 27 (fatty acid transporter), member 3 (222217_s_at), score: -0.34 SLC2A1solute carrier family 2 (facilitated glucose transporter), member 1 (201250_s_at), score: 0.34 SLC2A10solute carrier family 2 (facilitated glucose transporter), member 10 (221024_s_at), score: -0.31 SLC35F2solute carrier family 35, member F2 (218826_at), score: -0.36 SLC39A8solute carrier family 39 (zinc transporter), member 8 (209267_s_at), score: -0.42 SLC46A3solute carrier family 46, member 3 (214719_at), score: -0.32 SLC4A5solute carrier family 4, sodium bicarbonate cotransporter, member 5 (204296_at), score: 0.32 SLC7A7solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 (204588_s_at), score: 0.4 SLCO3A1solute carrier organic anion transporter family, member 3A1 (219229_at), score: -0.32 SMYD3SET and MYND domain containing 3 (218788_s_at), score: 0.46 SOCS2suppressor of cytokine signaling 2 (203373_at), score: -0.31 SOD2superoxide dismutase 2, mitochondrial (221477_s_at), score: -0.3 SOD3superoxide dismutase 3, extracellular (205236_x_at), score: -0.68 SOX11SRY (sex determining region Y)-box 11 (204914_s_at), score: 0.65 SPP1secreted phosphoprotein 1 (209875_s_at), score: 0.32 SRPXsushi-repeat-containing protein, X-linked (204955_at), score: -0.34 SSR4signal sequence receptor, delta (translocon-associated protein delta) (201004_at), score: 0.33 ST3GAL6ST3 beta-galactoside alpha-2,3-sialyltransferase 6 (210942_s_at), score: 0.37 STC1stanniocalcin 1 (204597_x_at), score: -0.32 STEAP1six transmembrane epithelial antigen of the prostate 1 (205542_at), score: -0.32 STMN2stathmin-like 2 (203000_at), score: -0.47 STOMstomatin (201060_x_at), score: -0.3 SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (213247_at), score: -0.45 SVILsupervillin (202565_s_at), score: -0.37 SWAP70SWAP-70 protein (209307_at), score: -0.39 SYNPOsynaptopodin (202796_at), score: 0.34 TEX10testis expressed 10 (218104_at), score: -0.3 TGFBR3transforming growth factor, beta receptor III (204731_at), score: -0.32 THBDthrombomodulin (203887_s_at), score: -0.37 THBS3thrombospondin 3 (209561_at), score: 0.36 TIPARPTCDD-inducible poly(ADP-ribose) polymerase (212665_at), score: -0.45 TKTtransketolase (208699_x_at), score: -0.41 TLE1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (203221_at), score: -0.34 TMBIM4transmembrane BAX inhibitor motif containing 4 (219206_x_at), score: -0.32 TMEM45Atransmembrane protein 45A (219410_at), score: 0.39 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (202510_s_at), score: -0.53 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (210260_s_at), score: -0.41 TNFRSF11Btumor necrosis factor receptor superfamily, member 11b (204933_s_at), score: -0.41 TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (209354_at), score: -0.39 TNFRSF1Btumor necrosis factor receptor superfamily, member 1B (203508_at), score: -0.4 TNXAtenascin XA pseudogene (213451_x_at), score: -0.34 TNXBtenascin XB (216333_x_at), score: -0.44 TOM1target of myb1 (chicken) (202807_s_at), score: -0.3 TOR1AIP1torsin A interacting protein 1 (216100_s_at), score: -0.31 TP53BP2tumor protein p53 binding protein, 2 (203120_at), score: -0.5 TPCN1two pore segment channel 1 (217914_at), score: -0.32 TPI1triosephosphate isomerase 1 (213011_s_at), score: 0.42 TRAF3IP2TRAF3 interacting protein 2 (215411_s_at), score: -0.36 TRIB2tribbles homolog 2 (Drosophila) (202478_at), score: 0.38 TSC22D1TSC22 domain family, member 1 (215111_s_at), score: -0.36 TSC22D3TSC22 domain family, member 3 (208763_s_at), score: 0.4 TSPAN13tetraspanin 13 (217979_at), score: -0.34 UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (201387_s_at), score: 0.53 URB2URB2 ribosome biogenesis 2 homolog (S. cerevisiae) (205284_at), score: -0.35 USP7ubiquitin specific peptidase 7 (herpes virus-associated) (201498_at), score: -0.32 VGLL3vestigial like 3 (Drosophila) (220327_at), score: -0.34 WDR25WD repeat domain 25 (219609_at), score: 0.32 WDR3WD repeat domain 3 (218882_s_at), score: -0.31 WDR41WD repeat domain 41 (218055_s_at), score: 0.38 WNT2wingless-type MMTV integration site family member 2 (205648_at), score: 0.62 WNT5Awingless-type MMTV integration site family, member 5A (213425_at), score: 0.39 WTAPWilms tumor 1 associated protein (210285_x_at), score: -0.35 YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide (201020_at), score: 0.4 ZBTB20zinc finger and BTB domain containing 20 (205383_s_at), score: -0.4 ZMIZ1zinc finger, MIZ-type containing 1 (212124_at), score: -0.3 ZNF37Azinc finger protein 37A (214878_at), score: 0.35

Non-Entrez genes

Unknown, score:

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Id sample Experiment ExpName Array Syndrome Cell.line
ctrl b 08-03.CEL 2 1 DS-CC hgu133a none DS-CC 2
t21a 08-03.CEL 4 1 DS-CC hgu133a Down DS-CC 4
t21d 08-03.CEL 7 1 DS-CC hgu133a Down DS-CC 7
t21b 08-03.CEL 5 1 DS-CC hgu133a Down DS-CC 5
t21c 08-03.CEL 6 1 DS-CC hgu133a Down DS-CC 6

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