Under-expression is coded with green,
over-expression with red color.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
defense response
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
signal transduction
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.
transport
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism.
response to stress
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
cell surface receptor linked signal transduction
Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.
G-protein coupled receptor protein signaling pathway
The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.
cell-cell signaling
Any process that mediates the transfer of information from one cell to another.
neurological system process
A organ system process carried out by any of the organs or tissues of neurological system.
sensory perception
The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
peptide transport
The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of, within or between cells.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
cognition
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
localization
Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
all
This term is the most general term possible
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
signal transduction
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
extracellular space
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
monooxygenase activity
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
signal transducer activity
Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.
receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
transmembrane receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.
G-protein coupled receptor activity
A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.
binding
The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
oxygen binding
Interacting selectively with oxygen (O2).
neurotransmitter receptor activity
Combining with a neurotransmitter to initiate a change in cell activity.
neurotransmitter binding
Interacting selectively with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
molecular transducer activity
The molecular function that accepts an input of one form and creates an output of a different form.
all
This term is the most general term possible
neurotransmitter receptor activity
Combining with a neurotransmitter to initiate a change in cell activity.
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 04080 | 3.102e-04 | 2.699 | 13 | 78 | Neuroactive ligand-receptor interaction |
A1CFAPOBEC1 complementation factor (220951_s_at), score: -0.76 ABCG4ATP-binding cassette, sub-family G (WHITE), member 4 (207593_at), score: -0.61 ABOABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) (216716_at), score: -0.78 ACSL6acyl-CoA synthetase long-chain family member 6 (211207_s_at), score: -0.7 ADAMDEC1ADAM-like, decysin 1 (206134_at), score: -0.62 ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif, 7 (220705_s_at), score: -0.76 ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif, 9 (220287_at), score: -0.72 ADAMTSL4ADAMTS-like 4 (220578_at), score: -0.65 ADCY2adenylate cyclase 2 (brain) (217687_at), score: -0.62 ADD2adducin 2 (beta) (206807_s_at), score: -0.67 ADORA1adenosine A1 receptor (216220_s_at), score: -0.55 ADRA1Dadrenergic, alpha-1D-, receptor (210961_s_at), score: -0.62 ADRA2Aadrenergic, alpha-2A-, receptor (209869_at), score: -0.63 AGMATagmatine ureohydrolase (agmatinase) (219792_at), score: -0.63 AIPL1aryl hydrocarbon receptor interacting protein-like 1 (219977_at), score: -0.57 AKAP6A kinase (PRKA) anchor protein 6 (205359_at), score: -0.58 AKR1D1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (207102_at), score: -0.52 APOMapolipoprotein M (205682_x_at), score: -0.74 ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 (219103_at), score: -0.71 AZGP1alpha-2-glycoprotein 1, zinc-binding (217014_s_at), score: -0.67 BEANbrain expressed, associated with Nedd4 (214068_at), score: -0.6 BEND5BEN domain containing 5 (219670_at), score: -0.59 BMP10bone morphogenetic protein 10 (208292_at), score: -0.62 BRS3bombesin-like receptor 3 (207369_at), score: -0.76 BTNL3butyrophilin-like 3 (217207_s_at), score: -0.83 C10orf59chromosome 10 open reading frame 59 (220564_at), score: -0.56 C11orf1chromosome 11 open reading frame 1 (218925_s_at), score: -0.53 C15orf5chromosome 15 open reading frame 5 (208109_s_at), score: -0.67 C1orf61chromosome 1 open reading frame 61 (205103_at), score: -0.65 C1QL1complement component 1, q subcomponent-like 1 (205575_at), score: -0.57 C20orf149chromosome 20 open reading frame 149 (218010_x_at), score: -0.55 C21orf2chromosome 21 open reading frame 2 (203996_s_at), score: -0.63 C2orf54chromosome 2 open reading frame 54 (220149_at), score: -0.57 C7orf28Achromosome 7 open reading frame 28A (201974_s_at), score: -0.73 C8orf17chromosome 8 open reading frame 17 (208266_at), score: -0.65 C8orf60chromosome 8 open reading frame 60 (220712_at), score: -0.67 CA4carbonic anhydrase IV (206209_s_at), score: -0.71 CALCAcalcitonin-related polypeptide alpha (217561_at), score: -0.59 CASQ1calsequestrin 1 (fast-twitch, skeletal muscle) (219645_at), score: -0.51 CASZ1castor zinc finger 1 (220015_at), score: -0.69 CATSPER2cation channel, sperm associated 2 (217588_at), score: -0.66 CCDC71coiled-coil domain containing 71 (219893_at), score: -0.61 CCDC9coiled-coil domain containing 9 (206257_at), score: -0.69 CCND2cyclin D2 (200953_s_at), score: -0.53 CCR9chemokine (C-C motif) receptor 9 (207445_s_at), score: -0.59 CCRN4LCCR4 carbon catabolite repression 4-like (S. cerevisiae) (220671_at), score: -0.56 CD53CD53 molecule (203416_at), score: -0.63 CDH19cadherin 19, type 2 (206898_at), score: -0.55 CDH8cadherin 8, type 2 (217574_at), score: -0.52 CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (211883_x_at), score: -0.53 CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5 (201884_at), score: -0.72 CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (211657_at), score: -0.79 CHD2chromodomain helicase DNA binding protein 2 (203461_at), score: -0.68 CHN2chimerin (chimaerin) 2 (207486_x_at), score: -0.6 CHRNA6cholinergic receptor, nicotinic, alpha 6 (207568_at), score: -0.55 CHRNA9cholinergic receptor, nicotinic, alpha 9 (221107_at), score: -0.58 CHST4carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (220446_s_at), score: -0.66 CLDN10claudin 10 (205328_at), score: -0.73 CLDN18claudin 18 (214135_at), score: -0.62 CLEC4MC-type lectin domain family 4, member M (207995_s_at), score: -0.65 CLEC7AC-type lectin domain family 7, member A (221698_s_at), score: -0.62 CNKSR2connector enhancer of kinase suppressor of Ras 2 (206731_at), score: -0.6 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: -0.74 COL8A1collagen, type VIII, alpha 1 (214587_at), score: -0.51 CR1complement component (3b/4b) receptor 1 (Knops blood group) (217484_at), score: -0.61 CRYGDcrystallin, gamma D (207532_at), score: -0.54 CSN2casein beta (207951_at), score: -0.65 CTSEcathepsin E (205927_s_at), score: -0.56 CTTNBP2NLCTTNBP2 N-terminal like (214731_at), score: -0.6 CXCL10chemokine (C-X-C motif) ligand 10 (204533_at), score: -0.57 CXorf21chromosome X open reading frame 21 (220252_x_at), score: -0.56 CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6 (211295_x_at), score: -0.6 CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 9 (214421_x_at), score: -0.7 CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1 (1431_at), score: -0.63 CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 4 (205998_x_at), score: -0.69 D4S234EDNA segment on chromosome 4 (unique) 234 expressed sequence (209569_x_at), score: -0.55 DAOD-amino-acid oxidase (206878_at), score: -0.63 DAZ4deleted in azoospermia 4 (216351_x_at), score: -0.52 DESdesmin (216947_at), score: -0.75 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: -0.58 DLX4distal-less homeobox 4 (208216_at), score: -0.58 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: -0.64 DOHHdeoxyhypusine hydroxylase/monooxygenase (208141_s_at), score: -0.61 DRD5dopamine receptor D5 (208486_at), score: -0.85 DSC2desmocollin 2 (204751_x_at), score: -0.63 DTX4deltex homolog 4 (Drosophila) (212611_at), score: -0.62 DXS542X-linked retinopathy protein-like (222247_at), score: -0.59 EDARectodysplasin A receptor (220048_at), score: -0.64 EIF5Aeukaryotic translation initiation factor 5A (201123_s_at), score: -0.56 ELNelastin (212670_at), score: -0.72 EN1engrailed homeobox 1 (220559_at), score: -0.52 EPORerythropoietin receptor (396_f_at), score: -0.54 FAM38Bfamily with sequence similarity 38, member B (219602_s_at), score: -0.83 FAM46Cfamily with sequence similarity 46, member C (220306_at), score: -0.55 FAM75A3family with sequence similarity 75, member A3 (215935_at), score: -0.56 FGL1fibrinogen-like 1 (205305_at), score: -0.61 FKSG2apoptosis inhibitor (208588_at), score: -0.6 FLRT1fibronectin leucine rich transmembrane protein 1 (210414_at), score: -0.6 FMO4flavin containing monooxygenase 4 (206263_at), score: -0.64 FOLH1folate hydrolase (prostate-specific membrane antigen) 1 (217487_x_at), score: -0.56 FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (214088_s_at), score: -0.65 GAB1GRB2-associated binding protein 1 (207112_s_at), score: -0.63 GABRR2gamma-aminobutyric acid (GABA) receptor, rho 2 (208217_at), score: -0.63 GBA3glucosidase, beta, acid 3 (cytosolic) (219954_s_at), score: -0.56 GK2glycerol kinase 2 (215430_at), score: -0.54 GLTSCR1glioma tumor suppressor candidate region gene 1 (219445_at), score: -0.71 GNG4guanine nucleotide binding protein (G protein), gamma 4 (205184_at), score: -0.53 GNRHRgonadotropin-releasing hormone receptor (216341_s_at), score: -0.68 GP1BAglycoprotein Ib (platelet), alpha polypeptide (207389_at), score: -0.65 GP6glycoprotein VI (platelet) (220336_s_at), score: -0.63 GPATCH4G patch domain containing 4 (220596_at), score: -0.68 GPR12G protein-coupled receptor 12 (214558_at), score: -0.81 GPR63G protein-coupled receptor 63 (220993_s_at), score: -0.58 GPR85G protein-coupled receptor 85 (219898_at), score: -0.52 GRHL2grainyhead-like 2 (Drosophila) (219388_at), score: -0.65 GRIA1glutamate receptor, ionotropic, AMPA 1 (209793_at), score: -0.64 GRM6glutamate receptor, metabotropic 6 (208035_at), score: -0.62 HABP2hyaluronan binding protein 2 (206010_at), score: -0.54 HAO2hydroxyacid oxidase 2 (long chain) (220801_s_at), score: -0.59 HAVCR1hepatitis A virus cellular receptor 1 (207052_at), score: -0.56 HBBhemoglobin, beta (211696_x_at), score: -0.62 HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (215584_at), score: -0.62 HIST1H2ALhistone cluster 1, H2al (214554_at), score: -0.65 HIST1H4Dhistone cluster 1, H4d (208076_at), score: -0.61 HOXD4homeobox D4 (205522_at), score: -0.65 HS3ST2heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (219697_at), score: -0.6 HSPB6heat shock protein, alpha-crystallin-related, B6 (214767_s_at), score: -0.74 ICA1islet cell autoantigen 1, 69kDa (211740_at), score: -0.57 IFNA16interferon, alpha 16 (208448_x_at), score: -0.63 IFNA5interferon, alpha 5 (214569_at), score: -0.61 IFNGinterferon, gamma (210354_at), score: -0.56 IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (207901_at), score: -0.54 IL16interleukin 16 (lymphocyte chemoattractant factor) (209827_s_at), score: -0.65 INE1inactivation escape 1 (non-protein coding) (207252_at), score: -0.67 ITGB8integrin, beta 8 (211488_s_at), score: -0.59 ITIH2inter-alpha (globulin) inhibitor H2 (204987_at), score: -0.57 KALRNkalirin, RhoGEF kinase (206078_at), score: -0.52 KCNB1potassium voltage-gated channel, Shab-related subfamily, member 1 (211006_s_at), score: -0.54 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: -0.73 KCNMB4potassium large conductance calcium-activated channel, subfamily M, beta member 4 (219287_at), score: -0.69 KIF5Akinesin family member 5A (205318_at), score: -0.53 KIR3DX1killer cell immunoglobulin-like receptor, three domains, X1 (216428_x_at), score: -0.76 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: -0.82 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (205307_s_at), score: -0.54 KRT2keratin 2 (207908_at), score: -0.65 KRT8P12keratin 8 pseudogene 12 (222060_at), score: -0.65 LATS1LATS, large tumor suppressor, homolog 1 (Drosophila) (219813_at), score: -0.52 LAX1lymphocyte transmembrane adaptor 1 (207734_at), score: -0.53 LHX3LIM homeobox 3 (221670_s_at), score: -0.79 LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (211133_x_at), score: -0.57 LOC100133748similar to GTF2IRD2 protein (215569_at), score: -0.57 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: -0.78 LOC23117PI-3-kinase-related kinase SMG-1 isoform 1 homolog (211996_s_at), score: -0.57 LOC286434hypothetical protein LOC286434 (222196_at), score: -0.69 LOC389906similar to Serine/threonine-protein kinase PRKX (Protein kinase PKX1) (59433_at), score: -0.74 LOC730227hypothetical protein LOC730227 (215756_at), score: -0.63 LOC80054hypothetical LOC80054 (220465_at), score: -0.75 LOC93432maltase-glucoamylase-like pseudogene (216666_at), score: -0.58 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: -0.77 LONRF3LON peptidase N-terminal domain and ring finger 3 (220009_at), score: -0.84 LPAR4lysophosphatidic acid receptor 4 (206960_at), score: -0.56 LRRN2leucine rich repeat neuronal 2 (216164_at), score: -0.55 LRRTM4leucine rich repeat transmembrane neuronal 4 (220345_at), score: -0.53 LTBP4latent transforming growth factor beta binding protein 4 (210628_x_at), score: -0.54 MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1 (213013_at), score: -0.63 MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 (205050_s_at), score: -0.75 MAPK8IP3mitogen-activated protein kinase 8 interacting protein 3 (213178_s_at), score: -0.64 MBmyoglobin (204179_at), score: -0.78 MCTP2multiple C2 domains, transmembrane 2 (220603_s_at), score: -0.57 MDM4Mdm4 p53 binding protein homolog (mouse) (205655_at), score: -0.63 MEP1Bmeprin A, beta (207251_at), score: -0.71 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: -0.82 MGAT4Cmannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) (207447_s_at), score: -0.64 MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (203936_s_at), score: -0.69 MMRN2multimerin 2 (219091_s_at), score: -0.87 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: -0.82 MOGmyelin oligodendrocyte glycoprotein (214650_x_at), score: -0.52 MPP3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) (206186_at), score: -0.67 MSTP9macrophage stimulating, pseudogene 9 (213382_at), score: -0.66 MUC13mucin 13, cell surface associated (218687_s_at), score: -0.53 MUC3Amucin 3A, cell surface associated (217117_x_at), score: -0.76 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: -0.74 MYO1Amyosin IA (211916_s_at), score: -0.8 MYO5Cmyosin VC (218966_at), score: -0.58 N4BP3Nedd4 binding protein 3 (214775_at), score: -0.65 NCRNA00092non-protein coding RNA 92 (215861_at), score: -0.58 NCRNA00093non-protein coding RNA 93 (210723_x_at), score: -0.56 NEUROD2neurogenic differentiation 2 (210271_at), score: -0.59 NINninein (GSK3B interacting protein) (219285_s_at), score: -0.55 NOTCH4Notch homolog 4 (Drosophila) (205247_at), score: -0.68 NOVA1neuro-oncological ventral antigen 1 (205794_s_at), score: -0.52 NPY2Rneuropeptide Y receptor Y2 (210730_s_at), score: -0.7 NRN1neuritin 1 (218625_at), score: -0.89 NTNG1netrin G1 (206713_at), score: -0.64 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: -0.65 NTRK3neurotrophic tyrosine kinase, receptor, type 3 (217033_x_at), score: -0.66 NYXnyctalopin (221684_s_at), score: -0.69 OCLMoculomedin (208274_at), score: -0.59 OGFRopioid growth factor receptor (211512_s_at), score: -0.63 OR1D2olfactory receptor, family 1, subfamily D, member 2 (221464_at), score: -0.56 OR1E2olfactory receptor, family 1, subfamily E, member 2 (208587_s_at), score: -0.69 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: -0.8 OVOL2ovo-like 2 (Drosophila) (211778_s_at), score: -0.71 PAX4paired box 4 (207867_at), score: -0.63 PDE3Aphosphodiesterase 3A, cGMP-inhibited (206388_at), score: -0.52 PDE3Bphosphodiesterase 3B, cGMP-inhibited (208591_s_at), score: -0.52 PDZRN4PDZ domain containing ring finger 4 (220595_at), score: -0.54 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: -0.91 PEG3paternally expressed 3 (209242_at), score: -0.6 PGCprogastricsin (pepsinogen C) (205261_at), score: -0.67 PGK2phosphoglycerate kinase 2 (217009_at), score: -0.74 PHF20L1PHD finger protein 20-like 1 (222133_s_at), score: -0.72 PIGQphosphatidylinositol glycan anchor biosynthesis, class Q (204144_s_at), score: -0.52 PIK3IP1phosphoinositide-3-kinase interacting protein 1 (221757_at), score: -0.57 PIPOXpipecolic acid oxidase (221605_s_at), score: -0.66 PLA2G7phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (206214_at), score: -0.54 PLCL1phospholipase C-like 1 (205934_at), score: -0.57 PLEKHG6pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (220073_s_at), score: -0.54 PLUNCpalate, lung and nasal epithelium associated (220542_s_at), score: -0.74 PMP2peripheral myelin protein 2 (206826_at), score: -0.63 PNPLA2patatin-like phospholipase domain containing 2 (212705_x_at), score: -0.88 PON1paraoxonase 1 (206344_at), score: -0.55 POU4F1POU class 4 homeobox 1 (206940_s_at), score: -0.54 PPP4R4protein phosphatase 4, regulatory subunit 4 (220672_at), score: -0.73 PRB3proline-rich protein BstNI subfamily 3 (206998_x_at), score: -0.68 PRINSpsoriasis associated RNA induced by stress (non-protein coding) (216051_x_at), score: -0.58 PRKCBprotein kinase C, beta (209685_s_at), score: -0.54 PROL1proline rich, lacrimal 1 (208004_at), score: -0.55 PROX1prospero homeobox 1 (207401_at), score: -0.71 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: -0.97 PTPREprotein tyrosine phosphatase, receptor type, E (221840_at), score: -0.56 PYHIN1pyrin and HIN domain family, member 1 (216748_at), score: -0.74 RAB26RAB26, member RAS oncogene family (50965_at), score: -0.52 RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4 (205651_x_at), score: -0.56 RARAretinoic acid receptor, alpha (203749_s_at), score: -0.54 RASL11BRAS-like, family 11, member B (219142_at), score: -0.67 RETret proto-oncogene (205879_x_at), score: -0.7 RIMS2regulating synaptic membrane exocytosis 2 (215478_at), score: -0.53 RNASE2ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) (206111_at), score: -0.54 ROS1c-ros oncogene 1 , receptor tyrosine kinase (207569_at), score: -0.66 RP11-35N6.1plasticity related gene 3 (219732_at), score: -0.71 RP3-377H14.5hypothetical LOC285830 (222279_at), score: -0.71 RP4-692D3.1hypothetical protein LOC728621 (221171_at), score: -0.52 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: -0.87 RRHretinal pigment epithelium-derived rhodopsin homolog (208314_at), score: -0.65 S100A12S100 calcium binding protein A12 (205863_at), score: -0.64 S100A14S100 calcium binding protein A14 (218677_at), score: -0.75 SCARF1scavenger receptor class F, member 1 (206995_x_at), score: -0.57 SCN10Asodium channel, voltage-gated, type X, alpha subunit (208578_at), score: -0.74 SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (220574_at), score: -0.61 SERF1Bsmall EDRK-rich factor 1B (centromeric) (219982_s_at), score: -0.64 SERPINA1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (211429_s_at), score: -0.68 SERPINB13serpin peptidase inhibitor, clade B (ovalbumin), member 13 (211362_s_at), score: -0.54 SFMBT1Scm-like with four mbt domains 1 (213370_s_at), score: -0.57 SFTPBsurfactant protein B (214354_x_at), score: -0.58 SH3TC2SH3 domain and tetratricopeptide repeats 2 (219710_at), score: -0.58 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (207185_at), score: -0.8 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (207095_at), score: -0.78 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: -0.73 SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2 (208389_s_at), score: -0.57 SLC1A7solute carrier family 1 (glutamate transporter), member 7 (210923_at), score: -0.55 SLC26A10solute carrier family 26, member 10 (214951_at), score: -0.67 SLC26A4solute carrier family 26, member 4 (206529_x_at), score: -0.56 SLC4A10solute carrier family 4, sodium bicarbonate transporter, member 10 (206830_at), score: -0.57 SLC4A5solute carrier family 4, sodium bicarbonate cotransporter, member 5 (204296_at), score: -0.63 SLC6A14solute carrier family 6 (amino acid transporter), member 14 (219795_at), score: -0.52 SLCO1C1solute carrier organic anion transporter family, member 1C1 (220460_at), score: -0.64 SLCO2A1solute carrier organic anion transporter family, member 2A1 (204368_at), score: -0.52 SOCS3suppressor of cytokine signaling 3 (206359_at), score: -0.75 SP140SP140 nuclear body protein (207777_s_at), score: -0.6 SRCAPSnf2-related CREBBP activator protein (212275_s_at), score: -0.75 ST6GAL1ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 (201998_at), score: -0.69 STAP2signal transducing adaptor family member 2 (221610_s_at), score: -0.54 SULT1B1sulfotransferase family, cytosolic, 1B, member 1 (207601_at), score: -0.58 SYN2synapsin II (210247_at), score: -0.6 TAAR2trace amine associated receptor 2 (221394_at), score: -0.62 TAC3tachykinin 3 (219992_at), score: -0.53 TACR1tachykinin receptor 1 (208048_at), score: -0.95 TAS2R16taste receptor, type 2, member 16 (221444_at), score: -0.62 TAS2R9taste receptor, type 2, member 9 (221461_at), score: -0.66 TBX21T-box 21 (220684_at), score: -0.79 TBX6T-box 6 (207684_at), score: -0.78 TLR1toll-like receptor 1 (210176_at), score: -0.53 TMEM19transmembrane protein 19 (219941_at), score: -0.55 TMEM92transmembrane protein 92 (216791_at), score: -0.69 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: -0.62 TNFSF9tumor necrosis factor (ligand) superfamily, member 9 (206907_at), score: -0.53 TP63tumor protein p63 (209863_s_at), score: -0.7 TRA@T cell receptor alpha locus (216540_at), score: -0.89 TRIM10tripartite motif-containing 10 (56748_at), score: -0.56 TRIM45tripartite motif-containing 45 (219923_at), score: -0.64 TRPM3transient receptor potential cation channel, subfamily M, member 3 (220463_at), score: -0.6 TSPY1testis specific protein, Y-linked 1 (216374_at), score: -0.6 TULP2tubby like protein 2 (206733_at), score: -0.57 VGFVGF nerve growth factor inducible (205586_x_at), score: -1 ZNF117zinc finger protein 117 (207605_x_at), score: -0.55 ZNF287zinc finger protein 287 (216453_at), score: -0.68 ZNF440zinc finger protein 440 (215892_at), score: -0.53
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| ctrl a 08-03.CEL | 1 | 1 | DS-CC | hgu133a | none | DS-CC 1 |
| t21a 08-03.CEL | 4 | 1 | DS-CC | hgu133a | Down | DS-CC 4 |
| t21d 08-03.CEL | 7 | 1 | DS-CC | hgu133a | Down | DS-CC 7 |
| 2Twin.CEL | 2 | 2 | DS-twin | hgu133plus2 | none | DS-twin 2 |
| E-TABM-263-raw-cel-1515485651.cel | 1 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
