Previous module | Next module Module #967, TG: 2.2, TC: 1.8, 305 probes, 305 Entrez genes, 9 conditions

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Expression data for module #967

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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skeletal system development

The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

all

This term is the most general term possible

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cell surface

The external part of the cell wall and/or plasma membrane.

endomembrane system

A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

melanosome

A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

receptor complex

Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

pigment granule

A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04060 3.315e-02 4.621 13
115 Cytokine-cytokine receptor interaction

Help | Hide | Top miRNA test for over-representation

Id Pvalue ExpCount Count Size
miR-320/320abcd 1.179e-02 16.88 38
372

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACBD3acyl-Coenzyme A binding domain containing 3 (202323_s_at), score: -0.44 ACLYATP citrate lyase (210337_s_at), score: -0.74 ACTR2ARP2 actin-related protein 2 homolog (yeast) (200727_s_at), score: -0.46 ADAM10ADAM metallopeptidase domain 10 (214895_s_at), score: -0.69 AGFG1ArfGAP with FG repeats 1 (213926_s_at), score: -0.52 AGPSalkylglycerone phosphate synthase (205401_at), score: -0.4 AKIRIN1akirin 1 (217893_s_at), score: -0.56 ALDH18A1aldehyde dehydrogenase 18 family, member A1 (217791_s_at), score: -0.42 ANKFY1ankyrin repeat and FYVE domain containing 1 (219868_s_at), score: -0.45 ANKLE2ankyrin repeat and LEM domain containing 2 (212201_at), score: -0.44 ANTXR1anthrax toxin receptor 1 (220092_s_at), score: -0.41 APLP2amyloid beta (A4) precursor-like protein 2 (208702_x_at), score: -0.66 ARF1ADP-ribosylation factor 1 (208750_s_at), score: -0.6 ARF6ADP-ribosylation factor 6 (203311_s_at), score: -0.55 ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) (216266_s_at), score: -0.57 ARHGDIARho GDP dissociation inhibitor (GDI) alpha (213606_s_at), score: -0.44 ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (221039_s_at), score: -0.53 ASPHaspartate beta-hydroxylase (205808_at), score: -0.71 ATP13A3ATPase type 13A3 (219558_at), score: -0.89 ATP6AP2ATPase, H+ transporting, lysosomal accessory protein 2 (201444_s_at), score: -0.44 ATP6V0A1ATPase, H+ transporting, lysosomal V0 subunit a1 (205095_s_at), score: -0.39 ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (201971_s_at), score: -0.65 B4GALT5UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (221484_at), score: -0.47 BAG5BCL2-associated athanogene 5 (202984_s_at), score: -0.46 BCLAF1BCL2-associated transcription factor 1 (201101_s_at), score: -0.52 BICD2bicaudal D homolog 2 (Drosophila) (209203_s_at), score: -0.45 BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) (210214_s_at), score: -0.57 BSGbasigin (Ok blood group) (208677_s_at), score: -0.39 C14orf1chromosome 14 open reading frame 1 (217188_s_at), score: -0.56 C19orf6chromosome 19 open reading frame 6 (213986_s_at), score: -0.59 C20orf30chromosome 20 open reading frame 30 (220477_s_at), score: -0.61 C4orf18chromosome 4 open reading frame 18 (219872_at), score: -0.54 CALD1caldesmon 1 (201616_s_at), score: -0.49 CALUcalumenin (214845_s_at), score: -0.74 CANXcalnexin (208853_s_at), score: -0.47 CAPN7calpain 7 (203357_s_at), score: -0.43 CAPRIN1cell cycle associated protein 1 (200722_s_at), score: -0.53 CBFBcore-binding factor, beta subunit (206788_s_at), score: -0.76 CD44CD44 molecule (Indian blood group) (210916_s_at), score: -0.55 CD46CD46 molecule, complement regulatory protein (211574_s_at), score: -0.61 CDH11cadherin 11, type 2, OB-cadherin (osteoblast) (207172_s_at), score: -0.45 CDV3CDV3 homolog (mouse) (213548_s_at), score: -0.96 CLIC4chloride intracellular channel 4 (201559_s_at), score: -0.69 CLINT1clathrin interactor 1 (201768_s_at), score: -0.42 CLIP1CAP-GLY domain containing linker protein 1 (210716_s_at), score: -0.58 COL6A1collagen, type VI, alpha 1 (212940_at), score: -0.56 COPAcoatomer protein complex, subunit alpha (214336_s_at), score: -0.85 CPDcarboxypeptidase D (201942_s_at), score: -0.85 CPNE3copine III (202118_s_at), score: -0.48 CRKv-crk sarcoma virus CT10 oncogene homolog (avian) (202226_s_at), score: -0.54 CSF1colony stimulating factor 1 (macrophage) (209716_at), score: -0.39 CSNK1A1casein kinase 1, alpha 1 (206562_s_at), score: -0.38 CUL4Bcullin 4B (202213_s_at), score: -0.44 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: -0.87 DAPK3death-associated protein kinase 3 (203890_s_at), score: -0.65 DAZAP2DAZ associated protein 2 (212595_s_at), score: -0.76 DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (201211_s_at), score: -0.74 DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 9 (212105_s_at), score: -0.78 DIMT1LDIM1 dimethyladenosine transferase 1-like (S. cerevisiae) (210802_s_at), score: -0.54 DLG1discs, large homolog 1 (Drosophila) (202514_at), score: -0.41 DNAJB1DnaJ (Hsp40) homolog, subfamily B, member 1 (200664_s_at), score: -0.57 DNAJB4DnaJ (Hsp40) homolog, subfamily B, member 4 (203811_s_at), score: -0.64 DNASE2deoxyribonuclease II, lysosomal (214992_s_at), score: -0.48 DSTdystonin (212253_x_at), score: -0.48 EDIL3EGF-like repeats and discoidin I-like domains 3 (207379_at), score: -0.42 EDN1endothelin 1 (218995_s_at), score: -0.41 EGR3early growth response 3 (206115_at), score: -0.39 EIF4G1eukaryotic translation initiation factor 4 gamma, 1 (208624_s_at), score: -0.54 EIF5Aeukaryotic translation initiation factor 5A (201123_s_at), score: -0.48 ELL2elongation factor, RNA polymerase II, 2 (214446_at), score: -0.48 EML4echinoderm microtubule associated protein like 4 (220386_s_at), score: -0.5 ENSAendosulfine alpha (221487_s_at), score: -0.41 EPB41L2erythrocyte membrane protein band 4.1-like 2 (201718_s_at), score: -0.53 EPRSglutamyl-prolyl-tRNA synthetase (200841_s_at), score: -0.45 ERLIN1ER lipid raft associated 1 (202444_s_at), score: -0.65 EXOC5exocyst complex component 5 (218748_s_at), score: -0.69 EZRezrin (208621_s_at), score: -0.55 FAM108B1family with sequence similarity 108, member B1 (220285_at), score: -0.57 FBN1fibrillin 1 (202765_s_at), score: -0.43 FGF5fibroblast growth factor 5 (210310_s_at), score: -0.65 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: -0.54 FGFR1fibroblast growth factor receptor 1 (210973_s_at), score: -0.52 FHOD1formin homology 2 domain containing 1 (218530_at), score: -0.45 FKBP15FK506 binding protein 15, 133kDa (76897_s_at), score: -0.41 FKBP1AFK506 binding protein 1A, 12kDa (210186_s_at), score: -0.78 FN1fibronectin 1 (214701_s_at), score: -0.62 FUSIP1FUS interacting protein (serine/arginine-rich) 1 (210178_x_at), score: -0.41 GALNT10UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) (207357_s_at), score: -0.42 GDE1glycerophosphodiester phosphodiesterase 1 (202593_s_at), score: -0.49 GDI2GDP dissociation inhibitor 2 (200008_s_at), score: -0.45 GFPT1glutamine-fructose-6-phosphate transaminase 1 (202721_s_at), score: -0.42 GLRXglutaredoxin (thioltransferase) (209276_s_at), score: -0.46 GLUD1glutamate dehydrogenase 1 (200946_x_at), score: -0.51 GLUD2glutamate dehydrogenase 2 (215794_x_at), score: -0.61 GNA13guanine nucleotide binding protein (G protein), alpha 13 (206917_at), score: -0.62 GNSglucosamine (N-acetyl)-6-sulfatase (203676_at), score: -0.83 GPC4glypican 4 (204983_s_at), score: -0.44 GPNMBglycoprotein (transmembrane) nmb (201141_at), score: -0.4 GPR176G protein-coupled receptor 176 (206673_at), score: -0.69 GPR183G protein-coupled receptor 183 (205419_at), score: -0.42 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: -0.4 GRAMD3GRAM domain containing 3 (218706_s_at), score: -0.57 GTF2Igeneral transcription factor II, i (210892_s_at), score: -0.66 H2BFSH2B histone family, member S (208579_x_at), score: -0.48 HADHAhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit (208629_s_at), score: -0.45 HBEGFheparin-binding EGF-like growth factor (203821_at), score: -0.43 HERC4hect domain and RLD 4 (208055_s_at), score: -0.45 HIP1huntingtin interacting protein 1 (205425_at), score: -0.61 HIPK3homeodomain interacting protein kinase 3 (210148_at), score: -0.74 HLA-Cmajor histocompatibility complex, class I, C (211799_x_at), score: -0.39 HNRNPH1heterogeneous nuclear ribonucleoprotein H1 (H) (213470_s_at), score: -0.45 HOXB6homeobox B6 (205366_s_at), score: -0.63 HP1BP3heterochromatin protein 1, binding protein 3 (220633_s_at), score: -0.48 HSPA4heat shock 70kDa protein 4 (211016_x_at), score: -0.66 HSPH1heat shock 105kDa/110kDa protein 1 (208744_x_at), score: -0.38 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: -0.41 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: -0.38 IGFBP5insulin-like growth factor binding protein 5 (203424_s_at), score: -0.39 IGFBP7insulin-like growth factor binding protein 7 (201162_at), score: -0.38 IL13RA1interleukin 13 receptor, alpha 1 (210904_s_at), score: -0.43 IL1RAPinterleukin 1 receptor accessory protein (205227_at), score: -0.39 IL23Ainterleukin 23, alpha subunit p19 (211796_s_at), score: -0.54 IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor) (211000_s_at), score: -0.5 IMPAD1inositol monophosphatase domain containing 1 (218516_s_at), score: -0.4 ITGA4integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (205885_s_at), score: -0.66 JMJD3jumonji domain containing 3, histone lysine demethylase (213146_at), score: -0.4 JUNDjun D proto-oncogene (203751_x_at), score: -0.41 KCTD20potassium channel tetramerisation domain containing 20 (214849_at), score: -0.52 KDELR3KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 (207265_s_at), score: -0.39 KIDINS220kinase D-interacting substrate, 220kDa (212162_at), score: -0.44 KITLGKIT ligand (211124_s_at), score: -0.64 KPNA4karyopherin alpha 4 (importin alpha 3) (209653_at), score: -0.83 LAMP1lysosomal-associated membrane protein 1 (201551_s_at), score: -0.66 LARP5La ribonucleoprotein domain family, member 5 (208953_at), score: -0.55 LDLRlow density lipoprotein receptor (202068_s_at), score: -0.5 LEPROTleptin receptor overlapping transcript (202378_s_at), score: -0.49 LIG4ligase IV, DNA, ATP-dependent (206235_at), score: -0.46 LIMS1LIM and senescent cell antigen-like domains 1 (207198_s_at), score: -0.56 LMAN1lectin, mannose-binding, 1 (203294_s_at), score: -0.78 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: -0.38 LOC100128809similar to hCG2045829 (215707_s_at), score: -0.74 LOC100133166similar to neighbor of BRCA1 gene 1 (201383_s_at), score: -0.51 LOC285412similar to KIAA0737 protein (217448_s_at), score: -0.46 LOC729148nuclear undecaprenyl pyrophosphate synthase 1 pseudogene (215207_x_at), score: -0.51 LOXL2lysyl oxidase-like 2 (202997_s_at), score: -0.45 M6PRmannose-6-phosphate receptor (cation dependent) (200900_s_at), score: -0.43 MADDMAP-kinase activating death domain (38398_at), score: 1 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: -0.48 MAP2K3mitogen-activated protein kinase kinase 3 (207667_s_at), score: -0.67 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: -0.73 MAP3K7mitogen-activated protein kinase kinase kinase 7 (211537_x_at), score: -0.64 MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (210284_s_at), score: -0.75 MAP4K5mitogen-activated protein kinase kinase kinase kinase 5 (203553_s_at), score: -0.53 MAPK1mitogen-activated protein kinase 1 (208351_s_at), score: -0.69 MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2 (201461_s_at), score: -0.74 MARCH7membrane-associated ring finger (C3HC4) 7 (202654_x_at), score: -0.56 MAT2Amethionine adenosyltransferase II, alpha (200769_s_at), score: -0.8 MAXMYC associated factor X (210734_x_at), score: -0.81 MBNL2muscleblind-like 2 (Drosophila) (205018_s_at), score: -0.62 MED6mediator complex subunit 6 (207079_s_at), score: -0.48 MEIS3P1Meis homeobox 3 pseudogene 1 (214077_x_at), score: -0.43 MFN2mitofusin 2 (216205_s_at), score: -0.52 MGAT2mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (211061_s_at), score: -0.47 MMP14matrix metallopeptidase 14 (membrane-inserted) (202827_s_at), score: -0.48 MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast) (201299_s_at), score: -0.5 MTMR2myotubularin related protein 2 (214649_s_at), score: -0.38 NAB1NGFI-A binding protein 1 (EGR1 binding protein 1) (208047_s_at), score: -0.61 NBPF14neuroblastoma breakpoint family, member 14 (201104_x_at), score: -0.46 NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (210162_s_at), score: -0.46 NID1nidogen 1 (202008_s_at), score: -0.8 NMD3NMD3 homolog (S. cerevisiae) (218036_x_at), score: -0.46 NNTnicotinamide nucleotide transhydrogenase (202784_s_at), score: -0.44 NOTCH2Notch homolog 2 (Drosophila) (210756_s_at), score: -0.62 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: -0.43 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: -0.49 OSMRoncostatin M receptor (205729_at), score: -0.73 PAFAH1B1platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa (211547_s_at), score: -0.66 PAPOLApoly(A) polymerase alpha (212720_at), score: -0.52 PCDHGA11protocadherin gamma subfamily A, 11 (211876_x_at), score: -0.88 PCDHGA3protocadherin gamma subfamily A, 3 (216352_x_at), score: -0.69 PCYOX1prenylcysteine oxidase 1 (203803_at), score: -0.5 PCYT1Aphosphate cytidylyltransferase 1, choline, alpha (204210_s_at), score: -0.38 PDCD1LG2programmed cell death 1 ligand 2 (220049_s_at), score: -0.38 PDE5Aphosphodiesterase 5A, cGMP-specific (206757_at), score: -0.39 PDLIM5PDZ and LIM domain 5 (216804_s_at), score: -0.39 PGRMC1progesterone receptor membrane component 1 (201120_s_at), score: -0.43 PHTF2putative homeodomain transcription factor 2 (217097_s_at), score: -0.84 PICALMphosphatidylinositol binding clathrin assembly protein (215236_s_at), score: -0.91 PIP5K1Aphosphatidylinositol-4-phosphate 5-kinase, type I, alpha (211205_x_at), score: -0.5 PKP2plakophilin 2 (207717_s_at), score: -0.43 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: -0.39 POM121POM121 membrane glycoprotein (rat) (212178_s_at), score: -0.49 PPAP2Aphosphatidic acid phosphatase type 2A (209147_s_at), score: -0.48 PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit (201835_s_at), score: -0.58 PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (200604_s_at), score: -0.53 PRPF4PRP4 pre-mRNA processing factor 4 homolog (yeast) (209162_s_at), score: -0.46 PRPF4BPRP4 pre-mRNA processing factor 4 homolog B (yeast) (211090_s_at), score: -0.71 PRRX1paired related homeobox 1 (205991_s_at), score: -0.8 PSEN1presenilin 1 (207782_s_at), score: -0.62 PSME4proteasome (prosome, macropain) activator subunit 4 (212220_at), score: -0.47 PTBP1polypyrimidine tract binding protein 1 (212016_s_at), score: -0.76 PTP4A1protein tyrosine phosphatase type IVA, member 1 (200730_s_at), score: -0.48 PTPN11protein tyrosine phosphatase, non-receptor type 11 (209896_s_at), score: -0.6 PTPN12protein tyrosine phosphatase, non-receptor type 12 (216915_s_at), score: -0.62 PTPN14protein tyrosine phosphatase, non-receptor type 14 (205503_at), score: -0.67 PTPRAprotein tyrosine phosphatase, receptor type, A (213799_s_at), score: -0.53 PTPROprotein tyrosine phosphatase, receptor type, O (211600_at), score: -0.68 PXNpaxillin (211823_s_at), score: -0.7 RAB3GAP1RAB3 GTPase activating protein subunit 1 (catalytic) (212932_at), score: -0.47 RAB5ARAB5A, member RAS oncogene family (206113_s_at), score: -0.81 RAB5CRAB5C, member RAS oncogene family (201156_s_at), score: -0.78 RANBP2RAN binding protein 2 (201711_x_at), score: -0.81 RANBP9RAN binding protein 9 (202583_s_at), score: -0.47 RASA3RAS p21 protein activator 3 (206220_s_at), score: -0.44 RCAN1regulator of calcineurin 1 (215253_s_at), score: -0.68 RDXradixin (204969_s_at), score: -0.54 RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian) (209878_s_at), score: -0.45 RGPD5RANBP2-like and GRIP domain containing 5 (210676_x_at), score: -0.44 RGS4regulator of G-protein signaling 4 (204338_s_at), score: -0.55 RIOK3RIO kinase 3 (yeast) (202129_s_at), score: -0.57 RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 1 (209941_at), score: -0.42 RNF141ring finger protein 141 (219104_at), score: -0.4 RNF6ring finger protein (C3H2C3 type) 6 (210932_s_at), score: -0.41 RNFT1ring finger protein, transmembrane 1 (221194_s_at), score: -0.38 RRADRas-related associated with diabetes (204802_at), score: -0.39 RRP7Bribosomal RNA processing 7 homolog B (S. cerevisiae) (214828_s_at), score: -0.49 RYKRYK receptor-like tyrosine kinase (216976_s_at), score: -0.51 SCAMP1secretory carrier membrane protein 1 (206667_s_at), score: -0.62 SCARB2scavenger receptor class B, member 2 (201647_s_at), score: -0.68 SCYL2SCY1-like 2 (S. cerevisiae) (221220_s_at), score: -0.51 SDHCsuccinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (216591_s_at), score: -0.58 SEC23ASec23 homolog A (S. cerevisiae) (204344_s_at), score: -0.45 SEC23IPSEC23 interacting protein (216392_s_at), score: -0.61 SELTselenoprotein T (217811_at), score: -0.44 SENP3SUMO1/sentrin/SMT3 specific peptidase 3 (215113_s_at), score: -0.5 SEPT10septin 10 (214720_x_at), score: -0.47 SEPT11septin 11 (201308_s_at), score: -0.56 SFRS1splicing factor, arginine/serine-rich 1 (201742_x_at), score: -0.45 SFRS2Bsplicing factor, arginine/serine-rich 2B (213152_s_at), score: -0.45 SFRS5splicing factor, arginine/serine-rich 5 (212266_s_at), score: -0.48 SGCBsarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (205121_at), score: -0.44 SGPP1sphingosine-1-phosphate phosphatase 1 (221268_s_at), score: -0.57 SKAP2src kinase associated phosphoprotein 2 (216899_s_at), score: -0.6 SLC12A4solute carrier family 12 (potassium/chloride transporters), member 4 (209401_s_at), score: -0.4 SLC1A1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 (213664_at), score: -0.4 SLC20A2solute carrier family 20 (phosphate transporter), member 2 (202744_at), score: -0.4 SLC35E1solute carrier family 35, member E1 (222263_at), score: -0.44 SLC39A6solute carrier family 39 (zinc transporter), member 6 (202089_s_at), score: -0.39 SLC7A6solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (203578_s_at), score: -0.39 SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 (209830_s_at), score: -0.48 SMEK1SMEK homolog 1, suppressor of mek1 (Dictyostelium) (220368_s_at), score: -0.51 SNAP23synaptosomal-associated protein, 23kDa (214544_s_at), score: -0.69 SPAG9sperm associated antigen 9 (206748_s_at), score: -0.62 SPRED2sprouty-related, EVH1 domain containing 2 (212458_at), score: -0.38 SPTLC1serine palmitoyltransferase, long chain base subunit 1 (202278_s_at), score: -0.51 SQLEsqualene epoxidase (213562_s_at), score: -0.72 SRPRsignal recognition particle receptor (docking protein) (200917_s_at), score: -0.57 SS18synovial sarcoma translocation, chromosome 18 (216684_s_at), score: -0.55 STAT1signal transducer and activator of transcription 1, 91kDa (AFFX-HUMISGF3A/M97935_MA_at), score: -0.51 STAT3signal transducer and activator of transcription 3 (acute-phase response factor) (208992_s_at), score: -0.59 STIP1stress-induced-phosphoprotein 1 (212009_s_at), score: -0.7 STOMstomatin (201060_x_at), score: -0.53 SYPL1synaptophysin-like 1 (201259_s_at), score: -0.64 TAF9BTAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa (221618_s_at), score: -0.57 TBL1XR1transducin (beta)-like 1 X-linked receptor 1 (221428_s_at), score: -0.5 TBX3T-box 3 (219682_s_at), score: -0.38 TFCP2transcription factor CP2 (207627_s_at), score: -0.39 TFDP1transcription factor Dp-1 (204147_s_at), score: -0.49 TGFBR1transforming growth factor, beta receptor 1 (206943_at), score: -0.4 TGFBR2transforming growth factor, beta receptor II (70/80kDa) (207334_s_at), score: -0.74 TIMM23translocase of inner mitochondrial membrane 23 homolog (yeast) (218119_at), score: -0.39 TJP1tight junction protein 1 (zona occludens 1) (214168_s_at), score: -0.59 TM6SF1transmembrane 6 superfamily member 1 (219892_at), score: -0.4 TM9SF1transmembrane 9 superfamily member 1 (209149_s_at), score: -0.41 TM9SF4transmembrane 9 superfamily protein member 4 (212194_s_at), score: -0.42 TMCO3transmembrane and coiled-coil domains 3 (220240_s_at), score: -0.4 TMED2transmembrane emp24 domain trafficking protein 2 (204426_at), score: -0.53 TMX1thioredoxin-related transmembrane protein 1 (208097_s_at), score: -0.6 TNFRSF10Dtumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (210654_at), score: -0.41 TNFRSF11Btumor necrosis factor receptor superfamily, member 11b (204933_s_at), score: -0.52 TOR1AIP1torsin A interacting protein 1 (216100_s_at), score: -0.67 TP53I11tumor protein p53 inducible protein 11 (214667_s_at), score: -0.47 TPP1tripeptidyl peptidase I (200742_s_at), score: -0.64 TSNtranslin (201504_s_at), score: -0.48 TSPAN3tetraspanin 3 (200973_s_at), score: -0.5 TTPALtocopherol (alpha) transfer protein-like (219633_at), score: -0.5 TUBB2Atubulin, beta 2A (209372_x_at), score: -0.4 TWF1twinfilin, actin-binding protein, homolog 1 (Drosophila) (214007_s_at), score: -0.64 TWSG1twisted gastrulation homolog 1 (Drosophila) (219201_s_at), score: -0.45 UBXN4UBX domain protein 4 (212008_at), score: -0.72 USP34ubiquitin specific peptidase 34 (212065_s_at), score: -0.54 UTRNutrophin (213022_s_at), score: -0.44 VAMP3vesicle-associated membrane protein 3 (cellubrevin) (201337_s_at), score: -0.66 VCLvinculin (200930_s_at), score: -0.38 VEGFAvascular endothelial growth factor A (211527_x_at), score: -0.55 WACWW domain containing adaptor with coiled-coil (219679_s_at), score: -0.84 WDR1WD repeat domain 1 (210935_s_at), score: -0.52 WTAPWilms tumor 1 associated protein (210285_x_at), score: -0.41 XPNPEP1X-prolyl aminopeptidase (aminopeptidase P) 1, soluble (208453_s_at), score: -0.49 YIPF5Yip1 domain family, member 5 (221423_s_at), score: -0.62 YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (210317_s_at), score: -0.46 YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (200641_s_at), score: -0.62 ZEB1zinc finger E-box binding homeobox 1 (212758_s_at), score: -0.4 ZFAND5zinc finger, AN1-type domain 5 (217741_s_at), score: -0.53 ZMYND11zinc finger, MYND domain containing 11 (202137_s_at), score: -0.57

Non-Entrez genes

Unknown, score:

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Id sample Experiment ExpName Array Syndrome Cell.line
46A.CEL 1 3 DS-mosaic hgu133plus2 none DS-mosaic 1
E-GEOD-3407-raw-cel-1437949854.cel 7 4 Cockayne hgu133a CS eGFP
3Twin.CEL 3 2 DS-twin hgu133plus2 Down DS-twin 3
E-GEOD-3407-raw-cel-1437949655.cel 3 4 Cockayne hgu133a none CSB
5CTwin.CEL 5 2 DS-twin hgu133plus2 Down DS-twin 5
E-TABM-263-raw-cel-1515486031.cel 20 6 Cycle hgu133a2 none Cycle 1
1Twin.CEL 1 2 DS-twin hgu133plus2 Down DS-twin 1
4Twin.CEL 4 2 DS-twin hgu133plus2 none DS-twin 4
ctrl c 08-03.CEL 3 1 DS-CC hgu133a none DS-CC 3

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