Under-expression is coded with green,
over-expression with red color.
MAPKKK cascade
Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways.
activation of MAPK activity
The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
immune system process
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
antigen processing and presentation of peptide antigen via MHC class I
The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
signal transduction
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
protein amino acid phosphorylation
The process of introducing a phosphate group on to a protein.
phosphorus metabolic process
The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
phosphate metabolic process
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
response to stress
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
intracellular signaling cascade
A series of reactions within the cell that occur as a result of a single trigger reaction or compound.
protein kinase cascade
A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.
JNK cascade
A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
activation of JUN kinase activity
The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
phosphorylation
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
antigen processing and presentation
The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
stress-activated protein kinase signaling pathway
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
cellular response to stress
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
positive regulation of kinase activity
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
positive regulation of catalytic activity
Any process that activates or increases the activity of an enzyme.
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.
regulation of MAP kinase activity
Any process that modulates the frequency, rate or extent of MAP kinase activity.
positive regulation of MAP kinase activity
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
biopolymer modification
The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer, resulting in a change in its properties.
regulation of JUN kinase activity
Any process that modulates the frequency, rate or extent of JUN kinase activity.
positive regulation of JUN kinase activity
Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
regulation of kinase activity
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
post-translational protein modification
The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
regulation of protein kinase activity
Any process that modulates the frequency, rate or extent of protein kinase activity.
positive regulation of protein kinase activity
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
antigen processing and presentation of peptide antigen
The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of catalytic activity
Any process that modulates the activity of an enzyme.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of transferase activity
Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
positive regulation of transferase activity
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
cellular response to stimulus
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
regulation of molecular function
Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding.
all
This term is the most general term possible
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
cellular response to stimulus
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
signal transduction
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.
cellular response to stress
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
stress-activated protein kinase signaling pathway
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
positive regulation of transferase activity
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
positive regulation of kinase activity
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
protein amino acid phosphorylation
The process of introducing a phosphate group on to a protein.
activation of MAPK activity
The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
JNK cascade
A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
positive regulation of protein kinase activity
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
activation of JUN kinase activity
The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
positive regulation of MAP kinase activity
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
activation of MAPK activity
The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
positive regulation of JUN kinase activity
Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
activation of JUN kinase activity
The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
all
This term is the most general term possible
ABCG4ATP-binding cassette, sub-family G (WHITE), member 4 (207593_at), score: 0.8 ABLIM3actin binding LIM protein family, member 3 (205730_s_at), score: -0.7 ACTN3actinin, alpha 3 (206891_at), score: 0.8 AGRNagrin (212285_s_at), score: -0.61 AIPL1aryl hydrocarbon receptor interacting protein-like 1 (219977_at), score: 0.87 ALDH1L1aldehyde dehydrogenase 1 family, member L1 (215798_at), score: 0.92 ANXA8L2annexin A8-like 2 (203074_at), score: 0.82 ARHGAP22Rho GTPase activating protein 22 (206298_at), score: -0.6 ARSAarylsulfatase A (204443_at), score: -0.8 BAIAP3BAI1-associated protein 3 (216356_x_at), score: 0.82 BAP1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (201419_at), score: -0.6 BAT2HLA-B associated transcript 2 (212081_x_at), score: -0.76 BAT2LHLA-B associated transcript 2-like (212068_s_at), score: -0.78 BCANbrevican (91920_at), score: 0.76 BCL7AB-cell CLL/lymphoma 7A (203795_s_at), score: -0.74 BTNL3butyrophilin-like 3 (217207_s_at), score: 0.92 C11orf21chromosome 11 open reading frame 21 (220560_at), score: 0.77 C1orf69chromosome 1 open reading frame 69 (215490_at), score: 0.86 C8orf60chromosome 8 open reading frame 60 (220712_at), score: 0.8 C9orf167chromosome 9 open reading frame 167 (219620_x_at), score: -0.76 CALB1calbindin 1, 28kDa (205626_s_at), score: 0.78 CALB2calbindin 2 (205428_s_at), score: 0.78 CAMK1calcium/calmodulin-dependent protein kinase I (204392_at), score: -0.69 CASQ1calsequestrin 1 (fast-twitch, skeletal muscle) (219645_at), score: 0.79 CD40CD40 molecule, TNF receptor superfamily member 5 (35150_at), score: 0.77 CD79BCD79b molecule, immunoglobulin-associated beta (205297_s_at), score: 0.89 CD97CD97 molecule (202910_s_at), score: -0.65 CDAcytidine deaminase (205627_at), score: -0.62 CDADC1cytidine and dCMP deaminase domain containing 1 (221015_s_at), score: 0.77 CHST4carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (220446_s_at), score: 0.95 CIZ1CDKN1A interacting zinc finger protein 1 (205516_x_at), score: -0.61 CLDN10claudin 10 (205328_at), score: 0.78 CLIP2CAP-GLY domain containing linker protein 2 (211031_s_at), score: -0.61 CLIP3CAP-GLY domain containing linker protein 3 (212358_at), score: -0.64 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: 0.94 COL18A1collagen, type XVIII, alpha 1 (209081_s_at), score: -0.76 CORO1Bcoronin, actin binding protein, 1B (64486_at), score: -0.63 COX6A2cytochrome c oxidase subunit VIa polypeptide 2 (206353_at), score: 0.77 CST3cystatin C (201360_at), score: -0.62 CYP24A1cytochrome P450, family 24, subfamily A, polypeptide 1 (206504_at), score: 0.79 CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 4 (205998_x_at), score: 0.78 DCAKDdephospho-CoA kinase domain containing (221224_s_at), score: 0.82 DEAF1deformed epidermal autoregulatory factor 1 (Drosophila) (209407_s_at), score: -0.66 DLX4distal-less homeobox 4 (208216_at), score: 0.78 DMPKdystrophia myotonica-protein kinase (37996_s_at), score: -0.68 DNAJB5DnaJ (Hsp40) homolog, subfamily B, member 5 (212817_at), score: -0.65 DNAJC4DnaJ (Hsp40) homolog, subfamily C, member 4 (206782_s_at), score: -0.7 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: 0.81 DOK4docking protein 4 (209691_s_at), score: -0.68 DSPPdentin sialophosphoprotein (221681_s_at), score: 0.82 ECE1endothelin converting enzyme 1 (201750_s_at), score: -0.59 ECM1extracellular matrix protein 1 (209365_s_at), score: -0.65 EDARectodysplasin A receptor (220048_at), score: 0.93 ERAP2endoplasmic reticulum aminopeptidase 2 (219759_at), score: -0.68 ETV7ets variant 7 (221680_s_at), score: 0.77 FAM65Afamily with sequence similarity 65, member A (45749_at), score: -0.64 FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide (204232_at), score: 0.79 FCF1FCF1 small subunit (SSU) processome component homolog (S. cerevisiae) (219927_at), score: 0.78 FGL1fibrinogen-like 1 (205305_at), score: 0.8 FHOD1formin homology 2 domain containing 1 (218530_at), score: -0.8 FOXK2forkhead box K2 (203064_s_at), score: -0.73 FURINfurin (paired basic amino acid cleaving enzyme) (201945_at), score: -0.68 FUT2fucosyltransferase 2 (secretor status included) (210608_s_at), score: 0.88 GABRR2gamma-aminobutyric acid (GABA) receptor, rho 2 (208217_at), score: 0.76 GBA3glucosidase, beta, acid 3 (cytosolic) (219954_s_at), score: 0.76 GDF9growth differentiation factor 9 (221314_at), score: 0.8 GM2AGM2 ganglioside activator (212737_at), score: -0.59 GMPRguanosine monophosphate reductase (204187_at), score: -0.68 GP1BAglycoprotein Ib (platelet), alpha polypeptide (207389_at), score: 0.83 GPATCH4G patch domain containing 4 (220596_at), score: 0.83 GPD1Lglycerol-3-phosphate dehydrogenase 1-like (212510_at), score: -0.66 GPX3glutathione peroxidase 3 (plasma) (214091_s_at), score: -0.6 GTPBP1GTP binding protein 1 (219357_at), score: -0.73 HAB1B1 for mucin (215778_x_at), score: 0.95 HAMPhepcidin antimicrobial peptide (220491_at), score: 0.86 HAO2hydroxyacid oxidase 2 (long chain) (220801_s_at), score: 0.8 HECTD3HECT domain containing 3 (218632_at), score: -0.59 HHEXhematopoietically expressed homeobox (215933_s_at), score: -0.66 HIST1H4Dhistone cluster 1, H4d (208076_at), score: 0.9 HLA-Emajor histocompatibility complex, class I, E (200904_at), score: -0.83 HLA-Fmajor histocompatibility complex, class I, F (204806_x_at), score: -0.61 HS3ST2heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (219697_at), score: 0.76 HSF1heat shock transcription factor 1 (202344_at), score: -0.84 IDUAiduronidase, alpha-L- (205059_s_at), score: -1 IL9Rinterleukin 9 receptor (217212_s_at), score: 0.91 INPP1inositol polyphosphate-1-phosphatase (202794_at), score: -0.61 ITGALintegrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (213475_s_at), score: 0.81 JUNDjun D proto-oncogene (203751_x_at), score: -0.59 JUPjunction plakoglobin (201015_s_at), score: -0.72 KCNJ14potassium inwardly-rectifying channel, subfamily J, member 14 (220776_at), score: 0.77 KCTD13potassium channel tetramerisation domain containing 13 (45653_at), score: -0.7 KIAA0317KIAA0317 (202128_at), score: -0.64 KIAA0913KIAA0913 (212359_s_at), score: -0.65 KIAA1009KIAA1009 (206005_s_at), score: 0.8 KLHL26kelch-like 26 (Drosophila) (219354_at), score: -0.73 LAX1lymphocyte transmembrane adaptor 1 (207734_at), score: 0.76 LEPREL2leprecan-like 2 (204854_at), score: -0.79 LIMS2LIM and senescent cell antigen-like domains 2 (220765_s_at), score: -0.6 LLGL2lethal giant larvae homolog 2 (Drosophila) (203713_s_at), score: 0.86 LOC149478hypothetical protein LOC149478 (215462_at), score: 0.78 LOC730227hypothetical protein LOC730227 (215756_at), score: 0.77 LRP5low density lipoprotein receptor-related protein 5 (209468_at), score: -0.7 MADCAM1mucosal vascular addressin cell adhesion molecule 1 (208037_s_at), score: 0.78 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: -0.61 MAN2B1mannosidase, alpha, class 2B, member 1 (209166_s_at), score: -0.69 MAP1Smicrotubule-associated protein 1S (218522_s_at), score: -0.87 MAP2K3mitogen-activated protein kinase kinase 3 (207667_s_at), score: -0.64 MAP3K11mitogen-activated protein kinase kinase kinase 11 (203652_at), score: -0.61 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: -0.59 MAP3K6mitogen-activated protein kinase kinase kinase 6 (219278_at), score: -0.76 MAPKAPK5mitogen-activated protein kinase-activated protein kinase 5 (212871_at), score: -0.6 MEOX1mesenchyme homeobox 1 (205619_s_at), score: 0.87 MGST2microsomal glutathione S-transferase 2 (204168_at), score: -0.64 MRPS2mitochondrial ribosomal protein S2 (218001_at), score: -0.61 MUL1mitochondrial E3 ubiquitin ligase 1 (218246_at), score: -0.69 MYH15myosin, heavy chain 15 (215331_at), score: 0.84 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: 0.79 NACAP1nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 (211445_x_at), score: 0.89 NCDNneurochondrin (209556_at), score: -0.63 NCRNA00093non-protein coding RNA 93 (210723_x_at), score: 0.88 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: -0.74 NINJ1ninjurin 1 (203045_at), score: -0.76 NOVA2neuro-oncological ventral antigen 2 (206477_s_at), score: 0.77 NPDC1neural proliferation, differentiation and control, 1 (218086_at), score: -0.65 OPRL1opiate receptor-like 1 (206564_at), score: 0.78 OR7E47Polfactory receptor, family 7, subfamily E, member 47 pseudogene (216698_x_at), score: 0.88 OS9osteosarcoma amplified 9, endoplasmic reticulum associated protein (200714_x_at), score: -0.59 PARVBparvin, beta (37965_at), score: -0.62 PCDHG@protocadherin gamma cluster (215836_s_at), score: -0.68 PDE7Bphosphodiesterase 7B (220343_at), score: 0.83 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: 0.88 PGCprogastricsin (pepsinogen C) (205261_at), score: 0.82 PHF7PHD finger protein 7 (215622_x_at), score: 0.95 PIP5K1Cphosphatidylinositol-4-phosphate 5-kinase, type I, gamma (212518_at), score: -0.87 PKN1protein kinase N1 (202161_at), score: -0.78 PKP2plakophilin 2 (207717_s_at), score: -0.73 PLAGL2pleiomorphic adenoma gene-like 2 (202925_s_at), score: -0.63 PLAUplasminogen activator, urokinase (211668_s_at), score: -0.64 PNMAL1PNMA-like 1 (218824_at), score: -0.6 PNPLA6patatin-like phospholipase domain containing 6 (203718_at), score: -0.63 POLRMTpolymerase (RNA) mitochondrial (DNA directed) (203782_s_at), score: -0.68 POLSpolymerase (DNA directed) sigma (202466_at), score: -0.61 PORP450 (cytochrome) oxidoreductase (208928_at), score: -0.64 PRAMEF11PRAME family member 11 (217365_at), score: 0.78 PRB3proline-rich protein BstNI subfamily 3 (206998_x_at), score: 0.85 PRKCBprotein kinase C, beta (209685_s_at), score: 0.9 PRKCDprotein kinase C, delta (202545_at), score: -0.9 PTGDSprostaglandin D2 synthase 21kDa (brain) (212187_x_at), score: -0.65 PTPN6protein tyrosine phosphatase, non-receptor type 6 (206687_s_at), score: 0.9 RAB11FIP3RAB11 family interacting protein 3 (class II) (203933_at), score: -0.6 RAB22ARAB22A, member RAS oncogene family (218360_at), score: -0.62 RALGPS2Ral GEF with PH domain and SH3 binding motif 2 (220338_at), score: 0.77 RICH2Rho-type GTPase-activating protein RICH2 (215232_at), score: 0.77 RLN1relaxin 1 (211753_s_at), score: 0.83 RNF130ring finger protein 130 (217865_at), score: -0.7 RNF24ring finger protein 24 (204669_s_at), score: -0.69 RNF40ring finger protein 40 (206845_s_at), score: -0.6 RP5-886K2.1neuronal thread protein AD7c-NTP (207953_at), score: 0.87 RPS17P5ribosomal protein S17 pseudogene 5 (216348_at), score: 0.89 S100A14S100 calcium binding protein A14 (218677_at), score: 0.86 SCAMP4secretory carrier membrane protein 4 (213244_at), score: -0.76 SCG2secretogranin II (chromogranin C) (204035_at), score: -0.65 SDAD1SDA1 domain containing 1 (218607_s_at), score: -0.59 SDC3syndecan 3 (202898_at), score: -0.64 SENP5SUMO1/sentrin specific peptidase 5 (213184_at), score: -0.61 SETXsenataxin (201964_at), score: -0.63 SH3GLB2SH3-domain GRB2-like endophilin B2 (218813_s_at), score: -0.59 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: -0.61 SIGIRRsingle immunoglobulin and toll-interleukin 1 receptor (TIR) domain (52940_at), score: -0.66 SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin (44673_at), score: 0.84 SIGLEC6sialic acid binding Ig-like lectin 6 (210796_x_at), score: 0.86 SIN3BSIN3 homolog B, transcription regulator (yeast) (209352_s_at), score: -0.83 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: 0.78 SLC1A7solute carrier family 1 (glutamate transporter), member 7 (210923_at), score: 0.8 SLC26A10solute carrier family 26, member 10 (214951_at), score: 0.93 SLC2A8solute carrier family 2 (facilitated glucose transporter), member 8 (218985_at), score: -0.65 SLC5A5solute carrier family 5 (sodium iodide symporter), member 5 (211123_at), score: 0.86 SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), member 1 (209453_at), score: -0.8 SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 (209830_s_at), score: -0.69 SMG6Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) (214940_s_at), score: -0.74 SMURF1SMAD specific E3 ubiquitin protein ligase 1 (212666_at), score: -0.63 SOLHsmall optic lobes homolog (Drosophila) (204275_at), score: -0.72 SORL1sortilin-related receptor, L(DLR class) A repeats-containing (203509_at), score: 0.85 SPARCL1SPARC-like 1 (hevin) (200795_at), score: 0.78 SPATA1spermatogenesis associated 1 (221057_at), score: 0.79 SPATA20spermatogenesis associated 20 (218164_at), score: -0.69 SPRY4sprouty homolog 4 (Drosophila) (221489_s_at), score: -0.71 SULT1B1sulfotransferase family, cytosolic, 1B, member 1 (207601_at), score: 0.91 SYT1synaptotagmin I (203999_at), score: -0.59 TAPBPTAP binding protein (tapasin) (208829_at), score: -0.81 TAS2R14taste receptor, type 2, member 14 (221391_at), score: 0.84 TBC1D2BTBC1 domain family, member 2B (212796_s_at), score: -0.65 TBX21T-box 21 (220684_at), score: 0.85 TEP1telomerase-associated protein 1 (205727_at), score: 0.77 TERF2telomeric repeat binding factor 2 (203611_at), score: -0.69 TGM4transglutaminase 4 (prostate) (217566_s_at), score: 0.83 TIAF1TGFB1-induced anti-apoptotic factor 1 (202039_at), score: -0.67 TLE6transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila) (222219_s_at), score: 0.82 TMCC2transmembrane and coiled-coil domain family 2 (213096_at), score: 0.85 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: 0.84 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (202510_s_at), score: -0.61 TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (207426_s_at), score: -0.62 TOB2transducer of ERBB2, 2 (221496_s_at), score: -0.59 TP53I11tumor protein p53 inducible protein 11 (214667_s_at), score: -0.72 TPD52tumor protein D52 (201690_s_at), score: -0.59 TRA@T cell receptor alpha locus (216540_at), score: 0.79 TSC2tuberous sclerosis 2 (215735_s_at), score: -0.66 TSSC4tumor suppressing subtransferable candidate 4 (218612_s_at), score: -0.64 TULP2tubby like protein 2 (206733_at), score: 0.84 UBTD1ubiquitin domain containing 1 (219172_at), score: -0.71 UBXN6UBX domain protein 6 (220757_s_at), score: -0.61 VEGFBvascular endothelial growth factor B (203683_s_at), score: -0.93 VPS37Bvacuolar protein sorting 37 homolog B (S. cerevisiae) (221704_s_at), score: -0.81 WDR42AWD repeat domain 42A (202249_s_at), score: -0.64 WDR6WD repeat domain 6 (217734_s_at), score: -0.65 WNT6wingless-type MMTV integration site family, member 6 (71933_at), score: 0.78 ZDHHC11zinc finger, DHHC-type containing 11 (221646_s_at), score: 0.78 ZFHX3zinc finger homeobox 3 (208033_s_at), score: -0.68 ZNF282zinc finger protein 282 (212892_at), score: -0.72 ZPBPzona pellucida binding protein (207021_at), score: 0.85
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| 46A.CEL | 1 | 3 | DS-mosaic | hgu133plus2 | none | DS-mosaic 1 |
| E-TABM-263-raw-cel-1515485711.cel | 4 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486071.cel | 22 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485691.cel | 3 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485871.cel | 12 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486211.cel | 29 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486031.cel | 20 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486411.cel | 39 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485771.cel | 7 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| t21a 08-03.CEL | 4 | 1 | DS-CC | hgu133a | Down | DS-CC 4 |
| E-TABM-263-raw-cel-1515485751.cel | 6 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 5CTwin.CEL | 5 | 2 | DS-twin | hgu133plus2 | Down | DS-twin 5 |
| t21d 08-03.CEL | 7 | 1 | DS-CC | hgu133a | Down | DS-CC 7 |
| 6Twin.CEL | 6 | 2 | DS-twin | hgu133plus2 | none | DS-twin 6 |
| E-TABM-263-raw-cel-1515486431.cel | 40 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 2Twin.CEL | 2 | 2 | DS-twin | hgu133plus2 | none | DS-twin 2 |
| E-GEOD-3407-raw-cel-1437949557.cel | 1 | 4 | Cockayne | hgu133a | CS | eGFP |
