Under-expression is coded with green,
over-expression with red color.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
immune effector process
Any process of the immune system that occurs as part of an immune response.
activation of immune response
Any process that initiates an immune response.
immune system process
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
acute inflammatory response
Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
activation of plasma proteins during acute inflammatory response
Any process activating plasma proteins via proteolysis during an acute inflammatory response.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
defense response
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
proteolysis
The hydrolysis of a peptide bond or bonds within a protein.
response to stress
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
inflammatory response
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
humoral immune response
An immune response mediated through a body fluid.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
response to external stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
response to wounding
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
all
This term is the most general term possible
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
immune effector process
Any process of the immune system that occurs as part of an immune response.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
response to wounding
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
activation of immune response
Any process that initiates an immune response.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
inflammatory response
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
activation of plasma proteins during acute inflammatory response
Any process activating plasma proteins via proteolysis during an acute inflammatory response.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
ABCA8ATP-binding cassette, sub-family A (ABC1), member 8 (204719_at), score: 1 BNC2basonuclin 2 (220272_at), score: 0.87 CD200CD200 molecule (209583_s_at), score: 0.98 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: 0.79 CFHcomplement factor H (213800_at), score: 0.91 CFHR1complement factor H-related 1 (215388_s_at), score: 0.87 CHRDL1chordin-like 1 (209763_at), score: 0.8 CMAHcytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) pseudogene (205518_s_at), score: 0.77 CUGBP2CUG triplet repeat, RNA binding protein 2 (202158_s_at), score: 0.78 DPYSL3dihydropyrimidinase-like 3 (201430_s_at), score: 0.77 DSG2desmoglein 2 (217901_at), score: 0.88 ERGv-ets erythroblastosis virus E26 oncogene homolog (avian) (213541_s_at), score: 0.8 FGL2fibrinogen-like 2 (204834_at), score: 0.87 GALNT12UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12) (218885_s_at), score: 0.79 GPR116G protein-coupled receptor 116 (212950_at), score: -0.87 GPR126G protein-coupled receptor 126 (213094_at), score: 0.84 GPR4G protein-coupled receptor 4 (206236_at), score: 0.82 HSPB8heat shock 22kDa protein 8 (221667_s_at), score: -0.82 IFI27interferon, alpha-inducible protein 27 (202411_at), score: 0.9 KCTD12potassium channel tetramerisation domain containing 12 (212192_at), score: 0.85 LAMA4laminin, alpha 4 (202202_s_at), score: 0.77 LAMC2laminin, gamma 2 (202267_at), score: 0.9 LIPGlipase, endothelial (219181_at), score: 0.81 MYH10myosin, heavy chain 10, non-muscle (212372_at), score: 0.8 MYLKmyosin light chain kinase (202555_s_at), score: -0.81 NFIBnuclear factor I/B (209289_at), score: 0.82 NOX4NADPH oxidase 4 (219773_at), score: 0.85 PARP3poly (ADP-ribose) polymerase family, member 3 (209940_at), score: -0.82 PLXNA2plexin A2 (213030_s_at), score: 0.79 RPP25ribonuclease P/MRP 25kDa subunit (219143_s_at), score: -0.84 UAP1L1UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 (214755_at), score: -0.82 ZFHX4zinc finger homeobox 4 (219779_at), score: 0.93 ZNF323zinc finger protein 323 (222016_s_at), score: 0.84
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-GEOD-3860-raw-cel-1561690231.cel | 4 | 5 | HGPS | hgu133a | HGPS | AG10750 |
| E-GEOD-3860-raw-cel-1561690432.cel | 16 | 5 | HGPS | hgu133a | HGPS | AG10750 |
| E-GEOD-3860-raw-cel-1561690336.cel | 9 | 5 | HGPS | hgu133a | HGPS | AG10750 |
| 1104_CNTL.CEL | 3 | 8 | WBS | hgu133plus2 | none | WBS 1 |
| E-GEOD-3860-raw-cel-1561690352.cel | 11 | 5 | HGPS | hgu133a | HGPS | AG11498 |
| E-GEOD-3860-raw-cel-1561690272.cel | 7 | 5 | HGPS | hgu133a | HGPS | AG11498 |
| E-GEOD-3860-raw-cel-1561690480.cel | 18 | 5 | HGPS | hgu133a | HGPS | AG11498 |
