Previous module | Next module Module #385, TG: 3.2, TC: 2, 136 probes, 136 Entrez genes, 8 conditions

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Expression data for module #385

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

biological adhesion

The attachment of a cell or organism to a substrate or other organism.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

all

This term is the most general term possible

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

proteinaceous extracellular matrix

A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

extracellular matrix

A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants).

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

structural molecule activity

The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell.

extracellular matrix structural constituent

The action of a molecule that contributes to the structural integrity of the extracellular matrix.

all

This term is the most general term possible

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
01430 2.168e-02 0.9523 6
59 Cell junctions
04512 2.168e-02 0.9523 6
59 ECM-receptor interaction

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ANK3ankyrin 3, node of Ranvier (ankyrin G) (206385_s_at), score: -0.64 ANKRD1ankyrin repeat domain 1 (cardiac muscle) (206029_at), score: -0.92 ANXA3annexin A3 (209369_at), score: -0.58 AUTS2autism susceptibility candidate 2 (212599_at), score: 0.73 B3GALT2UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 (217452_s_at), score: -0.58 BAALCbrain and acute leukemia, cytoplasmic (218899_s_at), score: 0.54 BACE2beta-site APP-cleaving enzyme 2 (217867_x_at), score: 0.61 BST1bone marrow stromal cell antigen 1 (205715_at), score: -0.73 C1orf54chromosome 1 open reading frame 54 (219506_at), score: -0.69 C1QTNF3C1q and tumor necrosis factor related protein 3 (220988_s_at), score: 0.72 C8orf84chromosome 8 open reading frame 84 (214725_at), score: -0.68 CA12carbonic anhydrase XII (203963_at), score: 0.58 CAMK2N1calcium/calmodulin-dependent protein kinase II inhibitor 1 (218309_at), score: 0.91 CAPGcapping protein (actin filament), gelsolin-like (201850_at), score: 0.57 CCDC81coiled-coil domain containing 81 (220389_at), score: -0.61 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: -0.68 CCR10chemokine (C-C motif) receptor 10 (220565_at), score: -0.62 CD34CD34 molecule (209543_s_at), score: -0.6 CDH4cadherin 4, type 1, R-cadherin (retinal) (206866_at), score: 0.68 CLGNcalmegin (205830_at), score: 0.6 COL4A1collagen, type IV, alpha 1 (211981_at), score: -0.62 COL4A5collagen, type IV, alpha 5 (213110_s_at), score: -0.58 COMPcartilage oligomeric matrix protein (205713_s_at), score: 0.56 CTSCcathepsin C (201487_at), score: -0.68 CYP1B1cytochrome P450, family 1, subfamily B, polypeptide 1 (202436_s_at), score: -0.71 DMDdystrophin (203881_s_at), score: -0.68 DNM1dynamin 1 (215116_s_at), score: 0.53 EDIL3EGF-like repeats and discoidin I-like domains 3 (207379_at), score: -0.66 EFEMP1EGF-containing fibulin-like extracellular matrix protein 1 (201842_s_at), score: -0.66 EIF2S3eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa (205321_at), score: -0.62 EMX2empty spiracles homeobox 2 (221950_at), score: 0.58 ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 (205066_s_at), score: 0.65 EPHA5EPH receptor A5 (215664_s_at), score: -0.89 F2Rcoagulation factor II (thrombin) receptor (203989_x_at), score: -0.84 FHL1four and a half LIM domains 1 (201539_s_at), score: -0.63 FHOD3formin homology 2 domain containing 3 (218980_at), score: 0.65 FOLR3folate receptor 3 (gamma) (206371_at), score: 0.57 FOXE1forkhead box E1 (thyroid transcription factor 2) (206912_at), score: -0.59 FSTfollistatin (204948_s_at), score: -0.69 FYCO1FYVE and coiled-coil domain containing 1 (218204_s_at), score: -0.61 GABBR2gamma-aminobutyric acid (GABA) B receptor, 2 (209990_s_at), score: 0.65 GPERG protein-coupled estrogen receptor 1 (210640_s_at), score: 0.6 GPR116G protein-coupled receptor 116 (212950_at), score: -0.81 HMOX1heme oxygenase (decycling) 1 (203665_at), score: 0.66 HOXC11homeobox C11 (206745_at), score: 0.56 HS3ST3A1heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 (219985_at), score: 0.78 IFI27interferon, alpha-inducible protein 27 (202411_at), score: -0.73 ISLRimmunoglobulin superfamily containing leucine-rich repeat (207191_s_at), score: 0.69 ITGA7integrin, alpha 7 (216331_at), score: -0.6 JAG1jagged 1 (Alagille syndrome) (216268_s_at), score: -0.81 KALRNkalirin, RhoGEF kinase (206078_at), score: -0.63 KCNE4potassium voltage-gated channel, Isk-related family, member 4 (222379_at), score: -0.59 KCNN4potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (204401_at), score: 0.73 KIAA0182KIAA0182 (212057_at), score: 0.56 KIAA1199KIAA1199 (212942_s_at), score: -0.59 KLF9Kruppel-like factor 9 (203543_s_at), score: -0.62 KRT18keratin 18 (201596_x_at), score: -0.78 LAMC2laminin, gamma 2 (202267_at), score: -0.65 LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein (200923_at), score: -0.68 LIPGlipase, endothelial (219181_at), score: -0.81 LMO2LIM domain only 2 (rhombotin-like 1) (204249_s_at), score: -0.79 LPHN2latrophilin 2 (206953_s_at), score: -0.83 LPXNleupaxin (216250_s_at), score: 0.69 LRRC15leucine rich repeat containing 15 (213909_at), score: 0.81 LRRC17leucine rich repeat containing 17 (205381_at), score: -0.73 LRRN3leucine rich repeat neuronal 3 (209841_s_at), score: -0.64 LYPD1LY6/PLAUR domain containing 1 (212909_at), score: -0.6 MBPmyelin basic protein (210136_at), score: -0.76 MEOX2mesenchyme homeobox 2 (206201_s_at), score: -1 MESTmesoderm specific transcript homolog (mouse) (202016_at), score: -0.82 MGPmatrix Gla protein (202291_s_at), score: -0.83 MMP14matrix metallopeptidase 14 (membrane-inserted) (202827_s_at), score: 0.6 MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (201069_at), score: 0.62 MSX1msh homeobox 1 (205932_s_at), score: 0.63 MT1Mmetallothionein 1M (217546_at), score: 0.65 MYCT1myc target 1 (220471_s_at), score: -0.67 NBL1neuroblastoma, suppression of tumorigenicity 1 (37005_at), score: 0.67 NDNnecdin homolog (mouse) (209550_at), score: 0.57 NDUFA4L2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 (218484_at), score: -0.8 NEDD9neural precursor cell expressed, developmentally down-regulated 9 (202149_at), score: -0.58 NET1neuroepithelial cell transforming 1 (201830_s_at), score: 0.69 NFASCneurofascin homolog (chicken) (213438_at), score: 0.55 NID2nidogen 2 (osteonidogen) (204114_at), score: -0.7 NKX3-1NK3 homeobox 1 (209706_at), score: 0.78 NMNAT2nicotinamide nucleotide adenylyltransferase 2 (209755_at), score: -0.59 NOVnephroblastoma overexpressed gene (214321_at), score: -0.68 NRG1neuregulin 1 (206343_s_at), score: 0.65 NRIP3nuclear receptor interacting protein 3 (219557_s_at), score: 0.56 NRXN3neurexin 3 (205795_at), score: -0.69 OLFM1olfactomedin 1 (213131_at), score: 0.57 OLFML3olfactomedin-like 3 (218162_at), score: 0.6 PBX1pre-B-cell leukemia homeobox 1 (212148_at), score: 0.57 PDE10Aphosphodiesterase 10A (205501_at), score: -0.75 PLA2G16phospholipase A2, group XVI (209581_at), score: -0.76 PLXND1plexin D1 (38671_at), score: -0.69 PNMA2paraneoplastic antigen MA2 (209598_at), score: -0.74 POSTNperiostin, osteoblast specific factor (210809_s_at), score: -0.73 PRKAG2protein kinase, AMP-activated, gamma 2 non-catalytic subunit (218292_s_at), score: -0.65 PTGER2prostaglandin E receptor 2 (subtype EP2), 53kDa (206631_at), score: 0.55 PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (204469_at), score: -0.77 PTX3pentraxin-related gene, rapidly induced by IL-1 beta (206157_at), score: -0.69 RAB15RAB15, member RAS onocogene family (221810_at), score: 0.63 RELNreelin (205923_at), score: -0.75 RGS7regulator of G-protein signaling 7 (206290_s_at), score: -0.67 RORARAR-related orphan receptor A (210426_x_at), score: 0.64 RTN1reticulon 1 (203485_at), score: -0.59 SCN9Asodium channel, voltage-gated, type IX, alpha subunit (206950_at), score: -0.6 SDPRserum deprivation response (phosphatidylserine binding protein) (218711_s_at), score: -0.65 SETBP1SET binding protein 1 (205933_at), score: 0.61 SFRP1secreted frizzled-related protein 1 (202036_s_at), score: 0.56 SGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein) (213543_at), score: 0.65 SLC24A3solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 (57588_at), score: -0.64 SLC25A4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 (202825_at), score: -0.66 SLC7A11solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (217678_at), score: -0.59 SLC7A8solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (216092_s_at), score: 0.81 SLCO3A1solute carrier organic anion transporter family, member 3A1 (219229_at), score: 0.63 SOBPsine oculis binding protein homolog (Drosophila) (218974_at), score: -0.61 SORBS2sorbin and SH3 domain containing 2 (204288_s_at), score: -0.62 SRGNserglycin (201859_at), score: -0.77 SSX2IPsynovial sarcoma, X breakpoint 2 interacting protein (203016_s_at), score: 0.61 STAT1signal transducer and activator of transcription 1, 91kDa (AFFX-HUMISGF3A/M97935_MA_at), score: -0.61 STEAP1six transmembrane epithelial antigen of the prostate 1 (205542_at), score: 0.54 STMN2stathmin-like 2 (203000_at), score: 0.63 SUSD5sushi domain containing 5 (214954_at), score: -0.68 SYNGR2synaptogyrin 2 (201079_at), score: -0.61 TFPItissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (209676_at), score: -0.64 TINAGL1tubulointerstitial nephritis antigen-like 1 (219058_x_at), score: -0.72 TLR4toll-like receptor 4 (221060_s_at), score: -0.66 TMEM158transmembrane protein 158 (213338_at), score: 0.83 TNXAtenascin XA pseudogene (213451_x_at), score: -0.74 TNXBtenascin XB (216333_x_at), score: -0.73 TUFT1tuftelin 1 (205807_s_at), score: -0.71 UBL3ubiquitin-like 3 (201535_at), score: 0.58 WWP2WW domain containing E3 ubiquitin protein ligase 2 (204022_at), score: -0.6 ZNF423zinc finger protein 423 (214761_at), score: -0.87 ZNF536zinc finger protein 536 (206403_at), score: 0.73

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
E-GEOD-3860-raw-cel-1561690248.cel 5 5 HGPS hgu133a HGPS AG11513
E-GEOD-3860-raw-cel-1561690304.cel 8 5 HGPS hgu133a none GMO8398C
E-GEOD-3860-raw-cel-1561690360.cel 12 5 HGPS hgu133a none GM0316B
E-GEOD-3860-raw-cel-1561690472.cel 17 5 HGPS hgu133a none GM00038C
E-GEOD-3860-raw-cel-1561690344.cel 10 5 HGPS hgu133a none GM00038C
E-GEOD-3860-raw-cel-1561690392.cel 14 5 HGPS hgu133a none GMO8398C
E-GEOD-3860-raw-cel-1561690223.cel 3 5 HGPS hgu133a none GM00038C
E-GEOD-3860-raw-cel-1561690256.cel 6 5 HGPS hgu133a none GMO8398C

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