Previous module | Next module Module #634, TG: 2.8, TC: 1.8, 82 probes, 82 Entrez genes, 9 conditions

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Expression data for module #634

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Under-expression is coded with green, over-expression with red color.

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immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

immune system development

The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

leukocyte differentiation

The process whereby a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell or any cell of the myeloid leukocyte or lymphocyte lineages.

myeloid leukocyte differentiation

The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

hemopoiesis

The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.

myeloid cell differentiation

The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.

osteoclast differentiation

The process whereby a relatively unspecialized monocyte acquires the specialized features of a osteoclast cell.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

hemopoietic or lymphoid organ development

The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

all

This term is the most general term possible

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

immune system development

The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

hemopoietic or lymphoid organ development

The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.

leukocyte differentiation

The process whereby a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell or any cell of the myeloid leukocyte or lymphocyte lineages.

myeloid cell differentiation

The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.

myeloid leukocyte differentiation

The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.

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Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04080 3.252e-02 0.7003 5
83 Neuroactive ligand-receptor interaction

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACSL4acyl-CoA synthetase long-chain family member 4 (202422_s_at), score: -0.7 ACTR3BARP3 actin-related protein 3 homolog B (yeast) (218868_at), score: -0.75 ADARadenosine deaminase, RNA-specific (201786_s_at), score: 0.7 ADORA2Badenosine A2b receptor (205891_at), score: 0.77 AHI1Abelson helper integration site 1 (221569_at), score: -0.81 AIM1absent in melanoma 1 (212543_at), score: 0.7 ANGPTL2angiopoietin-like 2 (213001_at), score: 0.69 ANXA10annexin A10 (210143_at), score: -0.89 APOL6apolipoprotein L, 6 (219716_at), score: 0.65 ARHGEF2rho/rac guanine nucleotide exchange factor (GEF) 2 (209435_s_at), score: 0.68 BIN1bridging integrator 1 (210201_x_at), score: 0.65 C13orf15chromosome 13 open reading frame 15 (218723_s_at), score: 0.68 C4orf43chromosome 4 open reading frame 43 (218513_at), score: -0.73 CALCOCO1calcium binding and coiled-coil domain 1 (209002_s_at), score: 0.74 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (205532_s_at), score: -0.71 CDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2) (213348_at), score: 0.68 CHUKconserved helix-loop-helix ubiquitous kinase (209666_s_at), score: -0.69 CLIP3CAP-GLY domain containing linker protein 3 (212358_at), score: 0.68 CRTC3CREB regulated transcription coactivator 3 (218648_at), score: 0.92 DENND2ADENN/MADD domain containing 2A (53991_at), score: 0.65 DEPDC6DEP domain containing 6 (218858_at), score: 0.74 DHRS3dehydrogenase/reductase (SDR family) member 3 (202481_at), score: 0.74 DNAJB9DnaJ (Hsp40) homolog, subfamily B, member 9 (202843_at), score: -0.82 DOCK10dedicator of cytokinesis 10 (219279_at), score: -0.73 DUSP4dual specificity phosphatase 4 (204014_at), score: -0.78 EAF2ELL associated factor 2 (219551_at), score: -0.74 EIF4Eeukaryotic translation initiation factor 4E (201436_at), score: -0.77 ESM1endothelial cell-specific molecule 1 (208394_x_at), score: -0.76 GFOD1glucose-fructose oxidoreductase domain containing 1 (219821_s_at), score: -0.73 GHRgrowth hormone receptor (205498_at), score: -0.69 GKglycerol kinase (207387_s_at), score: -0.79 GK3Pglycerol kinase 3 pseudogene (215966_x_at), score: -0.88 GMCL1germ cell-less homolog 1 (Drosophila) (218458_at), score: -0.79 GTF2A1Lgeneral transcription factor IIA, 1-like (213413_at), score: 0.77 HISPPD1histidine acid phosphatase domain containing 1 (203253_s_at), score: -0.75 HSPA12Aheat shock 70kDa protein 12A (214434_at), score: 0.72 IL33interleukin 33 (209821_at), score: -0.76 KAL1Kallmann syndrome 1 sequence (205206_at), score: -0.91 KIAA1305KIAA1305 (220911_s_at), score: 0.75 KIAA1462KIAA1462 (213316_at), score: 0.68 KLHL23kelch-like 23 (Drosophila) (213610_s_at), score: -0.77 LARP4La ribonucleoprotein domain family, member 4 (214155_s_at), score: -0.71 LOC100132540similar to LOC339047 protein (214870_x_at), score: 0.76 LOC339047hypothetical protein LOC339047 (221501_x_at), score: 0.77 LOC399491LOC399491 protein (214035_x_at), score: 0.71 LRP8low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (205282_at), score: -0.74 LRRN3leucine rich repeat neuronal 3 (209841_s_at), score: -0.73 LYPD1LY6/PLAUR domain containing 1 (212909_at), score: -0.72 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: 0.73 MC4Rmelanocortin 4 receptor (221467_at), score: -0.74 MFAP3Lmicrofibrillar-associated protein 3-like (205442_at), score: -0.74 MMP10matrix metallopeptidase 10 (stromelysin 2) (205680_at), score: -0.73 MMP16matrix metallopeptidase 16 (membrane-inserted) (207012_at), score: -0.75 MSTO1misato homolog 1 (Drosophila) (218296_x_at), score: -0.7 NEFMneurofilament, medium polypeptide (205113_at), score: -1 NPIPnuclear pore complex interacting protein (204538_x_at), score: 0.79 NPTX1neuronal pentraxin I (204684_at), score: -0.86 OPCMLopioid binding protein/cell adhesion molecule-like (214111_at), score: -0.83 ORAI3ORAI calcium release-activated calcium modulator 3 (221864_at), score: 0.67 OSTM1osteopetrosis associated transmembrane protein 1 (218196_at), score: -0.73 P2RY5purinergic receptor P2Y, G-protein coupled, 5 (218589_at), score: 0.68 PCDH9protocadherin 9 (219737_s_at), score: -0.91 PITX1paired-like homeodomain 1 (208502_s_at), score: 0.65 PNPLA2patatin-like phospholipase domain containing 2 (212705_x_at), score: 0.7 REREarginine-glutamic acid dipeptide (RE) repeats (200940_s_at), score: 0.76 ROR2receptor tyrosine kinase-like orphan receptor 2 (205578_at), score: 0.69 SLC25A13solute carrier family 25, member 13 (citrin) (203775_at), score: -0.74 SLC4A7solute carrier family 4, sodium bicarbonate cotransporter, member 7 (209884_s_at), score: -0.78 SLMO2slowmo homolog 2 (Drosophila) (217851_s_at), score: -0.72 SNNstannin (218032_at), score: 0.67 SSTR1somatostatin receptor 1 (208482_at), score: -0.71 TBC1D2BTBC1 domain family, member 2B (212796_s_at), score: 0.65 TICAM2toll-like receptor adaptor molecule 2 (214658_at), score: -0.72 TLR3toll-like receptor 3 (206271_at), score: 0.66 TMEM2transmembrane protein 2 (218113_at), score: -0.76 TP53tumor protein p53 (201746_at), score: 0.81 TRIM21tripartite motif-containing 21 (204804_at), score: 0.74 TRIM24tripartite motif-containing 24 (213301_x_at), score: -0.69 UHRF1BP1LUHRF1 binding protein 1-like (213118_at), score: -0.75 ULBP2UL16 binding protein 2 (221291_at), score: -0.77 WDR6WD repeat domain 6 (217734_s_at), score: 0.7 ZDHHC7zinc finger, DHHC-type containing 7 (218606_at), score: 0.8

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
E-TABM-263-raw-cel-1515486371.cel 37 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485891.cel 13 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485811.cel 9 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485771.cel 7 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485671.cel 2 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485751.cel 6 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485831.cel 10 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486271.cel 32 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486291.cel 33 6 Cycle hgu133a2 none Cycle 1

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