Under-expression is coded with green,
over-expression with red color.
regulation of DNA recombination
Any process that modulates the frequency, rate or extent of DNA recombination, a process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
cell activation
A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
somatic diversification of immune receptors
The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.
somatic recombination of immunoglobulin genes during immune response
The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response.
somatic diversification of immunoglobulins during immune response
The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response.
adaptive immune response
An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).
immune effector process
Any process of the immune system that occurs as part of an immune response.
immune system process
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
immunoglobulin production
The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
immunoglobulin production during immune response
The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.
production of molecular mediator of immune response
The synthesis or release of any molecular mediator of the immune response following an immunological stimulus, resulting in an increase in its intracellular or extracellular levels.
leukocyte mediated immunity
Any process involved in the carrying out of an immune response by a leukocyte.
lymphocyte mediated immunity
Any process involved in the carrying out of an immune response by a lymphocyte.
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies).
immune system development
The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
somatic diversification of immune receptors via germline recombination within a single locus
The process by which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.
regulation of immunoglobulin production
Any process that modulates the frequency, rate, or extent of immunoglobulin production.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
regulation of leukocyte activation
Any process that modulates the frequency, rate, or extent of leukocyte activation.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
regulation of immune effector process
Any process that modulates the frequency, rate, or extent of an immune effector process.
regulation of production of molecular mediator of immune response
Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.
regulation of leukocyte mediated immunity
Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.
regulation of lymphocyte mediated immunity
Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.
regulation of B cell mediated immunity
Any process that modulates the frequency, rate, or extent of B cell mediated immunity.
regulation of adaptive immune response
Any process that modulates the frequency, rate, or extent of an adaptive immune response.
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.
regulation of immunoglobulin mediated immune response
Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
DNA metabolic process
The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
DNA recombination
Any process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
immunoglobulin mediated immune response
An immune response mediated by immunoglobulins, whether cell-bound or in solution.
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
somatic cell DNA recombination
Recombination occurring within or between DNA molecules in somatic cells.
somatic diversification of immunoglobulins
The somatic process by means of which sequence diversity of immunoglobulins is generated.
somatic recombination of immunoglobulin gene segments
The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
regulation of metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
B cell mediated immunity
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
B cell activation
The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
isotype switching
The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
regulation of isotype switching
Any process that modulates the frequency, rate or extent of isotype switching.
leukocyte activation
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
positive regulation of isotype switching
Any process that activates or increases the frequency, rate or extent of isotype switching.
positive regulation of DNA recombination
Any process that activates or increases the frequency, rate or extent of DNA recombination.
lymphocyte activation
A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
isotype switching to IgG isotypes
The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.
regulation of isotype switching to IgG isotypes
Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
positive regulation of isotype switching to IgG isotypes
Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of developmental process
Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of B cell activation
Any process that modulates the frequency, rate or extent of B cell activation.
regulation of cell activation
Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
positive regulation of cell activation
Any process that activates or increases the frequency, rate or extent of activation.
positive regulation of B cell activation
Any process that activates or increases the frequency, rate or extent of B cell activation.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of DNA metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
positive regulation of DNA metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
regulation of lymphocyte activation
Any process that modulates the frequency, rate or extent of lymphocyte activation.
positive regulation of lymphocyte activation
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
regulation of macromolecule metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
all
This term is the most general term possible
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
regulation of metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of developmental process
Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
regulation of macromolecule metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
somatic diversification of immune receptors
The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
immune effector process
Any process of the immune system that occurs as part of an immune response.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
regulation of leukocyte activation
Any process that modulates the frequency, rate, or extent of leukocyte activation.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
leukocyte activation
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cell activation
Any process that activates or increases the frequency, rate or extent of activation.
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of cell activation
Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
regulation of isotype switching
Any process that modulates the frequency, rate or extent of isotype switching.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
somatic recombination of immunoglobulin gene segments
The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.
regulation of production of molecular mediator of immune response
Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.
regulation of leukocyte mediated immunity
Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
regulation of immune effector process
Any process that modulates the frequency, rate, or extent of an immune effector process.
regulation of adaptive immune response
Any process that modulates the frequency, rate, or extent of an adaptive immune response.
regulation of lymphocyte activation
Any process that modulates the frequency, rate or extent of lymphocyte activation.
positive regulation of lymphocyte activation
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
regulation of leukocyte activation
Any process that modulates the frequency, rate, or extent of leukocyte activation.
positive regulation of cell activation
Any process that activates or increases the frequency, rate or extent of activation.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
immune system development
The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
positive regulation of DNA metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
regulation of DNA metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
positive regulation of DNA metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
DNA metabolic process
The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
regulation of DNA metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
positive regulation of DNA metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
somatic recombination of immunoglobulin genes during immune response
The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response.
somatic diversification of immunoglobulins
The somatic process by means of which sequence diversity of immunoglobulins is generated.
regulation of immunoglobulin production
Any process that modulates the frequency, rate, or extent of immunoglobulin production.
regulation of lymphocyte mediated immunity
Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.
positive regulation of lymphocyte activation
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.
B cell mediated immunity
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
regulation of B cell activation
Any process that modulates the frequency, rate or extent of B cell activation.
positive regulation of B cell activation
Any process that activates or increases the frequency, rate or extent of B cell activation.
positive regulation of isotype switching to IgG isotypes
Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.
positive regulation of isotype switching
Any process that activates or increases the frequency, rate or extent of isotype switching.
regulation of isotype switching
Any process that modulates the frequency, rate or extent of isotype switching.
positive regulation of DNA recombination
Any process that activates or increases the frequency, rate or extent of DNA recombination.
regulation of DNA recombination
Any process that modulates the frequency, rate or extent of DNA recombination, a process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.
positive regulation of DNA recombination
Any process that activates or increases the frequency, rate or extent of DNA recombination.
isotype switching
The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
somatic diversification of immunoglobulins during immune response
The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response.
regulation of isotype switching
Any process that modulates the frequency, rate or extent of isotype switching.
regulation of B cell mediated immunity
Any process that modulates the frequency, rate, or extent of B cell mediated immunity.
regulation of isotype switching
Any process that modulates the frequency, rate or extent of isotype switching.
positive regulation of B cell activation
Any process that activates or increases the frequency, rate or extent of B cell activation.
regulation of B cell mediated immunity
Any process that modulates the frequency, rate, or extent of B cell mediated immunity.
positive regulation of isotype switching
Any process that activates or increases the frequency, rate or extent of isotype switching.
regulation of isotype switching
Any process that modulates the frequency, rate or extent of isotype switching.
positive regulation of isotype switching
Any process that activates or increases the frequency, rate or extent of isotype switching.
somatic diversification of immune receptors via germline recombination within a single locus
The process by which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.
immunoglobulin production during immune response
The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.
regulation of immunoglobulin mediated immune response
Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.
regulation of isotype switching to IgG isotypes
Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
positive regulation of isotype switching to IgG isotypes
Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.
regulation of isotype switching
Any process that modulates the frequency, rate or extent of isotype switching.
A1CFAPOBEC1 complementation factor (220951_s_at), score: 0.94 BMP10bone morphogenetic protein 10 (208292_at), score: 0.94 BTNL3butyrophilin-like 3 (217207_s_at), score: 0.99 C1orf61chromosome 1 open reading frame 61 (205103_at), score: 0.94 C8orf60chromosome 8 open reading frame 60 (220712_at), score: 0.91 CASZ1castor zinc finger 1 (220015_at), score: 0.88 CD53CD53 molecule (203416_at), score: 0.87 CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (211657_at), score: 0.95 CHN2chimerin (chimaerin) 2 (207486_x_at), score: 0.86 CHST4carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (220446_s_at), score: 0.87 CLDN10claudin 10 (205328_at), score: 0.87 CLEC4MC-type lectin domain family 4, member M (207995_s_at), score: 0.9 CNKSR2connector enhancer of kinase suppressor of Ras 2 (206731_at), score: 0.9 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: 0.89 CTSEcathepsin E (205927_s_at), score: 0.87 DHRS9dehydrogenase/reductase (SDR family) member 9 (219799_s_at), score: 0.87 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: 0.91 DRD5dopamine receptor D5 (208486_at), score: 0.89 GRHL2grainyhead-like 2 (Drosophila) (219388_at), score: 0.88 IFNGinterferon, gamma (210354_at), score: 0.86 IL16interleukin 16 (lymphocyte chemoattractant factor) (209827_s_at), score: 0.86 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: 0.88 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: 0.94 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (205307_s_at), score: 0.86 LHX3LIM homeobox 3 (221670_s_at), score: 1 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: 0.91 MMRN2multimerin 2 (219091_s_at), score: 0.95 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: 0.99 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: 0.88 MYO1Amyosin IA (211916_s_at), score: 0.91 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: 0.93 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: 1 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: 1 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: 0.97 PYHIN1pyrin and HIN domain family, member 1 (216748_at), score: 0.94 RETret proto-oncogene (205879_x_at), score: 0.95 RP11-35N6.1plasticity related gene 3 (219732_at), score: 0.94 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: 0.93 S100A14S100 calcium binding protein A14 (218677_at), score: 0.95 TBX21T-box 21 (220684_at), score: 0.97 TBX6T-box 6 (207684_at), score: 0.89 TP63tumor protein p63 (209863_s_at), score: 0.87 VGFVGF nerve growth factor inducible (205586_x_at), score: 0.96
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-TABM-263-raw-cel-1515485651.cel | 1 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486071.cel | 22 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486011.cel | 19 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485831.cel | 10 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 46A.CEL | 1 | 3 | DS-mosaic | hgu133plus2 | none | DS-mosaic 1 |
| 2Twin.CEL | 2 | 2 | DS-twin | hgu133plus2 | none | DS-twin 2 |
| t21d 08-03.CEL | 7 | 1 | DS-CC | hgu133a | Down | DS-CC 7 |
| E-GEOD-3407-raw-cel-1437949557.cel | 1 | 4 | Cockayne | hgu133a | CS | eGFP |
| t21a 08-03.CEL | 4 | 1 | DS-CC | hgu133a | Down | DS-CC 4 |
| ctrl a 08-03.CEL | 1 | 1 | DS-CC | hgu133a | none | DS-CC 1 |
