Previous module | Next module Module #713, TG: 2.6, TC: 2, 94 probes, 94 Entrez genes, 5 conditions

Help | Hide | Top Expression data


Expression data for module #713

color bar
Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

color bar

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

sensory perception

The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

cognition

The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.

all

This term is the most general term possible

Help | Hide | Top The GO tree — Cellular Components

color bar

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

Help | Hide | Top The GO tree — Molecular Function

color bar

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

neurotransmitter binding

Interacting selectively with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

A1CFAPOBEC1 complementation factor (220951_s_at), score: -0.73 ACSL6acyl-CoA synthetase long-chain family member 6 (211207_s_at), score: -0.68 ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif, 9 (220287_at), score: -0.68 BMP10bone morphogenetic protein 10 (208292_at), score: -0.7 BRS3bombesin-like receptor 3 (207369_at), score: -0.72 BTNL3butyrophilin-like 3 (217207_s_at), score: -0.74 C10orf59chromosome 10 open reading frame 59 (220564_at), score: -0.68 C7orf28Achromosome 7 open reading frame 28A (201974_s_at), score: -0.73 C8orf60chromosome 8 open reading frame 60 (220712_at), score: -0.69 CA4carbonic anhydrase IV (206209_s_at), score: -0.72 CATSPER2cation channel, sperm associated 2 (217588_at), score: -0.69 CCDC9coiled-coil domain containing 9 (206257_at), score: -0.74 CD53CD53 molecule (203416_at), score: -0.71 CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5 (201884_at), score: -0.72 CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (211657_at), score: -0.79 CHRNA9cholinergic receptor, nicotinic, alpha 9 (221107_at), score: -0.7 CLDN10claudin 10 (205328_at), score: -0.79 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: -0.67 CSN2casein beta (207951_at), score: -0.69 CXCL10chemokine (C-X-C motif) ligand 10 (204533_at), score: -0.72 CYBBcytochrome b-245, beta polypeptide (203923_s_at), score: -0.73 CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1 (1431_at), score: -0.67 DHRS9dehydrogenase/reductase (SDR family) member 9 (219799_s_at), score: -0.82 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: -0.74 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: -0.74 DOHHdeoxyhypusine hydroxylase/monooxygenase (208141_s_at), score: -0.74 DPTdermatopontin (213068_at), score: -0.68 DRD5dopamine receptor D5 (208486_at), score: -0.71 EDAectodysplasin A (211130_x_at), score: -0.77 ENPP4ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function) (204160_s_at), score: -0.75 FKSG2apoptosis inhibitor (208588_at), score: -0.72 FLRT1fibronectin leucine rich transmembrane protein 1 (210414_at), score: -0.67 FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (214088_s_at), score: -0.71 GPATCH4G patch domain containing 4 (220596_at), score: -0.69 GPR12G protein-coupled receptor 12 (214558_at), score: -0.81 HIVEP2human immunodeficiency virus type I enhancer binding protein 2 (212642_s_at), score: -0.67 HS3ST2heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (219697_at), score: -0.69 ITIH5inter-alpha (globulin) inhibitor H5 (219064_at), score: -0.73 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: -0.68 KIR3DX1killer cell immunoglobulin-like receptor, three domains, X1 (216428_x_at), score: -0.71 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: -0.74 KLHL4kelch-like 4 (Drosophila) (214591_at), score: -0.68 KRT2keratin 2 (207908_at), score: -0.71 LHX3LIM homeobox 3 (221670_s_at), score: -0.78 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: -0.77 LOC389906similar to Serine/threonine-protein kinase PRKX (Protein kinase PKX1) (59433_at), score: -0.7 LOC643293FLJ44451 pseudogene (215057_at), score: -0.7 LOC93432maltase-glucoamylase-like pseudogene (216666_at), score: -0.69 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: -0.75 LRRN2leucine rich repeat neuronal 2 (216164_at), score: -0.7 MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 (205050_s_at), score: -0.7 MBmyoglobin (204179_at), score: -0.69 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: -0.7 MMRN2multimerin 2 (219091_s_at), score: -0.99 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: -0.9 MSTP9macrophage stimulating, pseudogene 9 (213382_at), score: -0.67 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: -0.73 MYO1Amyosin IA (211916_s_at), score: -0.99 N4BP3Nedd4 binding protein 3 (214775_at), score: -0.75 NRN1neuritin 1 (218625_at), score: -0.82 NTNG1netrin G1 (206713_at), score: -0.67 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: -0.71 NTRK3neurotrophic tyrosine kinase, receptor, type 3 (217033_x_at), score: -0.74 OR1E2olfactory receptor, family 1, subfamily E, member 2 (208587_s_at), score: -0.8 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: -0.78 PAX4paired box 4 (207867_at), score: -0.67 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: -0.8 PGK2phosphoglycerate kinase 2 (217009_at), score: -0.8 PIPOXpipecolic acid oxidase (221605_s_at), score: -0.74 PNPLA2patatin-like phospholipase domain containing 2 (212705_x_at), score: -0.7 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: -1 PYHIN1pyrin and HIN domain family, member 1 (216748_at), score: -0.76 RASL11BRAS-like, family 11, member B (219142_at), score: -0.69 RETret proto-oncogene (205879_x_at), score: -0.68 RP11-35N6.1plasticity related gene 3 (219732_at), score: -0.87 RP3-377H14.5hypothetical LOC285830 (222279_at), score: -0.7 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: -0.79 RUNX3runt-related transcription factor 3 (204198_s_at), score: -0.67 S100A14S100 calcium binding protein A14 (218677_at), score: -0.73 SCN10Asodium channel, voltage-gated, type X, alpha subunit (208578_at), score: -0.78 SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (220574_at), score: -0.67 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (207185_at), score: -0.72 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (207095_at), score: -0.72 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: -0.71 SLC26A10solute carrier family 26, member 10 (214951_at), score: -0.68 SLCO1C1solute carrier organic anion transporter family, member 1C1 (220460_at), score: -0.74 STAP2signal transducing adaptor family member 2 (221610_s_at), score: -0.69 TACR1tachykinin receptor 1 (208048_at), score: -0.86 TAS2R9taste receptor, type 2, member 9 (221461_at), score: -0.67 TBX21T-box 21 (220684_at), score: -0.78 TBX6T-box 6 (207684_at), score: -0.75 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: -0.73 VGFVGF nerve growth factor inducible (205586_x_at), score: -0.94 WISP2WNT1 inducible signaling pathway protein 2 (205792_at), score: -0.71

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
ctrl a 08-03.CEL 1 1 DS-CC hgu133a none DS-CC 1
t21a 08-03.CEL 4 1 DS-CC hgu133a Down DS-CC 4
E-GEOD-3407-raw-cel-1437949557.cel 1 4 Cockayne hgu133a CS eGFP
ctrl c 08-03.CEL 3 1 DS-CC hgu133a none DS-CC 3
E-TABM-263-raw-cel-1515485651.cel 1 6 Cycle hgu133a2 none Cycle 1

Valid XHTML 1.1 Valid CSS! Best viewed with Firefox

© 2008-2010 Computational Biology Group, Department of Medical Genetics, University of Lausanne, Switzerland