Previous module | Next module Module #712, TG: 2.6, TC: 2, 133 probes, 133 Entrez genes, 5 conditions

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Expression data for module #712

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Under-expression is coded with green, over-expression with red color.

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Help | Hide | Top The GO tree — Cellular Components

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intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

endomembrane system

A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.

vesicle membrane

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

extracellular matrix

A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants).

organelle membrane

The lipid bilayer surrounding an organelle.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

melanosome membrane

The lipid bilayer surrounding a melanosome.

melanosome

A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

extracellular matrix part

Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

chitosome

An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum.

pigment granule

A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

organelle membrane

The lipid bilayer surrounding an organelle.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

extracellular matrix part

Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

organelle membrane

The lipid bilayer surrounding an organelle.

vesicle membrane

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle membrane

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

melanosome membrane

The lipid bilayer surrounding a melanosome.

melanosome membrane

The lipid bilayer surrounding a melanosome.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
00860 1.143e-02 0.2729 4
24 Porphyrin and chlorophyll metabolism
00040 2.443e-02 0.1478 3
13 Pentose and glucuronate interconversions

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

A2Malpha-2-macroglobulin (217757_at), score: 0.55 ABCB1ATP-binding cassette, sub-family B (MDR/TAP), member 1 (209993_at), score: 1 ABCB4ATP-binding cassette, sub-family B (MDR/TAP), member 4 (207819_s_at), score: 0.64 ABHD14Aabhydrolase domain containing 14A (210006_at), score: -0.42 ACIN1apoptotic chromatin condensation inducer 1 (201715_s_at), score: 0.53 AIM2absent in melanoma 2 (206513_at), score: 0.62 AKAP8LA kinase (PRKA) anchor protein 8-like (218064_s_at), score: 0.5 ANP32Aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A (201043_s_at), score: 0.52 APOBEC3Gapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G (204205_at), score: 0.49 ATP6V1B2ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 (201089_at), score: 0.58 BAALCbrain and acute leukemia, cytoplasmic (218899_s_at), score: -0.43 BAZ2Abromodomain adjacent to zinc finger domain, 2A (201353_s_at), score: 0.52 BHMT2betaine-homocysteine methyltransferase 2 (219902_at), score: 0.56 C10orf116chromosome 10 open reading frame 116 (203571_s_at), score: -0.4 C3orf64chromosome 3 open reading frame 64 (221935_s_at), score: -0.46 C4orf31chromosome 4 open reading frame 31 (219747_at), score: -0.46 C5orf30chromosome 5 open reading frame 30 (221823_at), score: -0.52 CA3carbonic anhydrase III, muscle specific (204865_at), score: 0.59 CDR2Lcerebellar degeneration-related protein 2-like (213230_at), score: -0.53 COL11A1collagen, type XI, alpha 1 (37892_at), score: -0.42 COPZ2coatomer protein complex, subunit zeta 2 (219561_at), score: -0.43 CRTAPcartilage associated protein (201380_at), score: -0.56 CRYABcrystallin, alpha B (209283_at), score: -0.49 DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 (208151_x_at), score: 0.67 DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (201211_s_at), score: 0.56 DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 9 (212105_s_at), score: 0.5 DIO2deiodinase, iodothyronine, type II (203699_s_at), score: 0.8 DUSP14dual specificity phosphatase 14 (203367_at), score: -0.43 ECM1extracellular matrix protein 1 (209365_s_at), score: -0.41 EPHB2EPH receptor B2 (209589_s_at), score: 0.66 FAM108A1family with sequence similarity 108, member A1 (221267_s_at), score: -0.42 FAM169Afamily with sequence similarity 169, member A (213954_at), score: 0.62 FAT1FAT tumor suppressor homolog 1 (Drosophila) (201579_at), score: -0.54 FKBP9FK506 binding protein 9, 63 kDa (212169_at), score: -0.59 FOLR3folate receptor 3 (gamma) (206371_at), score: -0.43 GAGE4G antigen 4 (207086_x_at), score: 0.93 GAGE6G antigen 6 (208155_x_at), score: 0.87 GAS6growth arrest-specific 6 (202177_at), score: -0.45 GATA3GATA binding protein 3 (209604_s_at), score: 0.75 GHRgrowth hormone receptor (205498_at), score: -0.41 GLSglutaminase (203159_at), score: -0.43 GLTPglycolipid transfer protein (219267_at), score: -0.45 HAS2hyaluronan synthase 2 (206432_at), score: -0.49 HERC5hect domain and RLD 5 (219863_at), score: 0.67 HGSNATheparan-alpha-glucosaminide N-acetyltransferase (218017_s_at), score: -0.57 HIST1H4Chistone cluster 1, H4c (205967_at), score: -0.46 HIVEP2human immunodeficiency virus type I enhancer binding protein 2 (212642_s_at), score: -0.48 HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2) (200751_s_at), score: 0.51 HNRNPH1heterogeneous nuclear ribonucleoprotein H1 (H) (213470_s_at), score: 0.52 HRASLSHRAS-like suppressor (219983_at), score: 0.5 HSPA4Lheat shock 70kDa protein 4-like (205543_at), score: 0.51 HSPB7heat shock 27kDa protein family, member 7 (cardiovascular) (218934_s_at), score: -0.54 IGFBP3insulin-like growth factor binding protein 3 (212143_s_at), score: -0.46 IPO8importin 8 (205701_at), score: 0.51 IRS2insulin receptor substrate 2 (209185_s_at), score: -0.55 ISLRimmunoglobulin superfamily containing leucine-rich repeat (207191_s_at), score: -0.42 KCNS3potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 (205968_at), score: -0.42 KIAA0495KIAA0495 (213340_s_at), score: -0.49 L1CAML1 cell adhesion molecule (204584_at), score: 0.55 LAMB3laminin, beta 3 (209270_at), score: 0.51 LDOC1leucine zipper, down-regulated in cancer 1 (204454_at), score: -0.45 LOC728855hypothetical LOC728855 (222001_x_at), score: 0.53 LRRC2leucine rich repeat containing 2 (219949_at), score: -0.52 LTBP2latent transforming growth factor beta binding protein 2 (204682_at), score: -0.45 M6PRmannose-6-phosphate receptor (cation dependent) (200900_s_at), score: 0.5 MAN2A1mannosidase, alpha, class 2A, member 1 (205105_at), score: -0.51 MARK1MAP/microtubule affinity-regulating kinase 1 (221047_s_at), score: 0.76 MED6mediator complex subunit 6 (207079_s_at), score: 0.51 MFAP5microfibrillar associated protein 5 (213764_s_at), score: -0.53 MITFmicrophthalmia-associated transcription factor (207233_s_at), score: 0.55 MT1P3metallothionein 1 pseudogene 3 (221953_s_at), score: -0.42 MYO1Cmyosin IC (214656_x_at), score: -0.6 NAPGN-ethylmaleimide-sensitive factor attachment protein, gamma (210048_at), score: 0.49 NCRNA00084non-protein coding RNA 84 (214657_s_at), score: 0.57 NEFLneurofilament, light polypeptide (221805_at), score: 0.7 NFASCneurofascin homolog (chicken) (213438_at), score: -0.41 NGDNneuroguidin, EIF4E binding protein (213794_s_at), score: 0.49 NMUneuromedin U (206023_at), score: 0.55 NOC2Lnucleolar complex associated 2 homolog (S. cerevisiae) (202115_s_at), score: 0.49 NOL12nucleolar protein 12 (219324_at), score: 0.5 NONOnon-POU domain containing, octamer-binding (208698_s_at), score: 0.56 NRGNneurogranin (protein kinase C substrate, RC3) (204081_at), score: 0.62 OASL2'-5'-oligoadenylate synthetase-like (210797_s_at), score: 0.95 PDE10Aphosphodiesterase 10A (205501_at), score: 0.56 PDPK13-phosphoinositide dependent protein kinase-1 (204524_at), score: -0.43 PILRBpaired immunoglobin-like type 2 receptor beta (220954_s_at), score: 0.6 PODXLpodocalyxin-like (201578_at), score: -0.45 PPM2Cprotein phosphatase 2C, magnesium-dependent, catalytic subunit (218273_s_at), score: 0.49 PQBP1polyglutamine binding protein 1 (214527_s_at), score: 0.51 PTGER3prostaglandin E receptor 3 (subtype EP3) (213933_at), score: -0.5 QPCTglutaminyl-peptide cyclotransferase (205174_s_at), score: -0.48 RAB7L1RAB7, member RAS oncogene family-like 1 (218700_s_at), score: 0.49 RABGAP1LRAB GTPase activating protein 1-like (213982_s_at), score: -0.52 REEP1receptor accessory protein 1 (204364_s_at), score: 0.52 RP6-213H19.1serine/threonine protein kinase MST4 (218499_at), score: 0.56 SGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein) (213543_at), score: -0.41 SIDT2SID1 transmembrane family, member 2 (56256_at), score: -0.41 SLC16A1solute carrier family 16, member 1 (monocarboxylic acid transporter 1) (209900_s_at), score: -0.42 SLC4A4solute carrier family 4, sodium bicarbonate cotransporter, member 4 (203908_at), score: -0.47 SLC7A11solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (217678_at), score: 0.52 SMEK1SMEK homolog 1, suppressor of mek1 (Dictyostelium) (220368_s_at), score: 0.58 SMG1SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) (210057_at), score: 0.5 SNAPC1small nuclear RNA activating complex, polypeptide 1, 43kDa (205443_at), score: 0.49 SNCAsynuclein, alpha (non A4 component of amyloid precursor) (204466_s_at), score: 0.7 SPARCsecreted protein, acidic, cysteine-rich (osteonectin) (212667_at), score: -0.48 SSR3signal sequence receptor, gamma (translocon-associated protein gamma) (217790_s_at), score: -0.46 SYTL2synaptotagmin-like 2 (220613_s_at), score: 0.5 TBC1D8TBC1 domain family, member 8 (with GRAM domain) (204526_s_at), score: 0.49 TCEAL2transcription elongation factor A (SII)-like 2 (211276_at), score: 0.76 TEKTEK tyrosine kinase, endothelial (206702_at), score: -0.5 TERF1telomeric repeat binding factor (NIMA-interacting) 1 (203448_s_at), score: 0.51 TIMP2TIMP metallopeptidase inhibitor 2 (203167_at), score: -0.5 TMEM204transmembrane protein 204 (219315_s_at), score: -0.43 TMEM47transmembrane protein 47 (209656_s_at), score: -0.5 TMOD1tropomodulin 1 (203661_s_at), score: 0.6 TNS1tensin 1 (221748_s_at), score: -0.46 TOB1transducer of ERBB2, 1 (202704_at), score: -0.45 TRIM8tripartite motif-containing 8 (221012_s_at), score: -0.41 TSPAN13tetraspanin 13 (217979_at), score: -0.45 TSPYL5TSPY-like 5 (213122_at), score: -0.4 TYRP1tyrosinase-related protein 1 (205694_at), score: 0.49 UAP1UDP-N-acteylglucosamine pyrophosphorylase 1 (209340_at), score: -0.47 UBL3ubiquitin-like 3 (201535_at), score: -0.55 UGT1A1UDP glucuronosyltransferase 1 family, polypeptide A1 (207126_x_at), score: 0.86 UGT1A6UDP glucuronosyltransferase 1 family, polypeptide A6 (206094_x_at), score: 0.87 UGT1A9UDP glucuronosyltransferase 1 family, polypeptide A9 (204532_x_at), score: 0.85 UROSuroporphyrinogen III synthase (203031_s_at), score: -0.4 USP18ubiquitin specific peptidase 18 (219211_at), score: 0.54 USP25ubiquitin specific peptidase 25 (220419_s_at), score: -0.41 VWA5Avon Willebrand factor A domain containing 5A (210102_at), score: 0.54 WDR48WD repeat domain 48 (222157_s_at), score: 0.51 WT1Wilms tumor 1 (206067_s_at), score: 0.62 ZNF415zinc finger protein 415 (205514_at), score: -0.43

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
E-GEOD-3407-raw-cel-1437949854.cel 7 4 Cockayne hgu133a CS eGFP
E-GEOD-3407-raw-cel-1437949938.cel 8 4 Cockayne hgu133a none CSB
E-GEOD-3407-raw-cel-1437949579.cel 2 4 Cockayne hgu133a none CSB
E-GEOD-3407-raw-cel-1437949750.cel 6 4 Cockayne hgu133a CS CSB
E-GEOD-3407-raw-cel-1437949721.cel 5 4 Cockayne hgu133a CS CSB

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