Previous module | Next module Module #753, TG: 2.6, TC: 1.6, 125 probes, 125 Entrez genes, 10 conditions

Help | Hide | Top Expression data


Expression data for module #753

color bar
Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

color bar

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

xenobiotic metabolic process

The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

response to xenobiotic stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

all

This term is the most general term possible

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

xenobiotic metabolic process

The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.

Help | Hide | Top The GO tree — Cellular Components

color bar

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

proteinaceous extracellular matrix

A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.

extracellular matrix

A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants).

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

Help | Hide | Top The GO tree — Molecular Function

color bar

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
00150 1.295e-02 0.285 4
21 Androgen and estrogen metabolism
00983 3.409e-02 0.3936 4
29 Drug metabolism - other enzymes
00040 3.710e-02 0.1764 3
13 Pentose and glucuronate interconversions

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ABCB1ATP-binding cassette, sub-family B (MDR/TAP), member 1 (209993_at), score: -1 ABCB4ATP-binding cassette, sub-family B (MDR/TAP), member 4 (207819_s_at), score: -0.71 ADORA2Badenosine A2b receptor (205891_at), score: -0.57 AIM2absent in melanoma 2 (206513_at), score: -0.62 AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase) (206561_s_at), score: -0.73 ANK3ankyrin 3, node of Ranvier (ankyrin G) (206385_s_at), score: -0.58 APH1Banterior pharynx defective 1 homolog B (C. elegans) (221036_s_at), score: 0.5 APOBEC3Gapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G (204205_at), score: -0.63 ARSJarylsulfatase family, member J (219973_at), score: 0.5 C10orf116chromosome 10 open reading frame 116 (203571_s_at), score: 0.53 C3orf64chromosome 3 open reading frame 64 (221935_s_at), score: 0.59 C5orf30chromosome 5 open reading frame 30 (221823_at), score: 0.62 CA3carbonic anhydrase III, muscle specific (204865_at), score: -0.59 CCNG1cyclin G1 (208796_s_at), score: 0.5 CD24CD24 molecule (209771_x_at), score: -0.66 CD248CD248 molecule, endosialin (219025_at), score: 0.58 CD81CD81 molecule (200675_at), score: 0.49 CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1) (202284_s_at), score: 0.61 COL11A1collagen, type XI, alpha 1 (37892_at), score: 0.6 CRTAPcartilage associated protein (201380_at), score: 0.61 CRYABcrystallin, alpha B (209283_at), score: 0.56 CTNNBL1catenin, beta like 1 (221021_s_at), score: -0.59 CTSKcathepsin K (202450_s_at), score: 0.52 DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 (208151_x_at), score: -0.6 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: -0.7 DHX38DEAH (Asp-Glu-Ala-His) box polypeptide 38 (209178_at), score: -0.58 DIO2deiodinase, iodothyronine, type II (203699_s_at), score: -0.84 DUSP14dual specificity phosphatase 14 (203367_at), score: 0.54 EPHB2EPH receptor B2 (209589_s_at), score: -0.72 FAM105Afamily with sequence similarity 105, member A (219694_at), score: -0.63 FAM169Afamily with sequence similarity 169, member A (213954_at), score: -0.64 FARP1FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) (201911_s_at), score: 0.48 FAT1FAT tumor suppressor homolog 1 (Drosophila) (201579_at), score: 0.65 FBN2fibrillin 2 (203184_at), score: 0.49 FKBP9FK506 binding protein 9, 63 kDa (212169_at), score: 0.63 FOXG1forkhead box G1 (206018_at), score: -0.57 GAGE4G antigen 4 (207086_x_at), score: -0.95 GAGE6G antigen 6 (208155_x_at), score: -0.91 GAS6growth arrest-specific 6 (202177_at), score: 0.51 GATA3GATA binding protein 3 (209604_s_at), score: -0.79 GLSglutaminase (203159_at), score: 0.61 GREM1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) (218469_at), score: 0.51 HAS2hyaluronan synthase 2 (206432_at), score: 0.53 HERC5hect domain and RLD 5 (219863_at), score: -0.78 HGSNATheparan-alpha-glucosaminide N-acetyltransferase (218017_s_at), score: 0.64 HIVEP2human immunodeficiency virus type I enhancer binding protein 2 (212642_s_at), score: 0.5 HRASLSHRAS-like suppressor (219983_at), score: -0.56 HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 1 (214359_s_at), score: -0.57 HSPB7heat shock 27kDa protein family, member 7 (cardiovascular) (218934_s_at), score: 0.52 IGSF3immunoglobulin superfamily, member 3 (202421_at), score: -0.6 IRS2insulin receptor substrate 2 (209185_s_at), score: 0.64 KYNUkynureninase (L-kynurenine hydrolase) (217388_s_at), score: -0.62 LAMB3laminin, beta 3 (209270_at), score: -0.58 LBHlimb bud and heart development homolog (mouse) (221011_s_at), score: 0.49 LDOC1leucine zipper, down-regulated in cancer 1 (204454_at), score: 0.52 LEF1lymphoid enhancer-binding factor 1 (221558_s_at), score: -0.72 LIPAlipase A, lysosomal acid, cholesterol esterase (201847_at), score: 0.52 LOC728855hypothetical LOC728855 (222001_x_at), score: -0.72 LRRC2leucine rich repeat containing 2 (219949_at), score: 0.61 LTBP2latent transforming growth factor beta binding protein 2 (204682_at), score: 0.64 MAGOHmago-nashi homolog, proliferation-associated (Drosophila) (210092_at), score: -0.57 MAN2A1mannosidase, alpha, class 2A, member 1 (205105_at), score: 0.62 MARCH2membrane-associated ring finger (C3HC4) 2 (210075_at), score: 0.49 MARK1MAP/microtubule affinity-regulating kinase 1 (221047_s_at), score: -0.63 MFAP5microfibrillar associated protein 5 (213764_s_at), score: 0.59 MOXD1monooxygenase, DBH-like 1 (209708_at), score: 0.59 MRC2mannose receptor, C type 2 (37408_at), score: 0.54 MXRA5matrix-remodelling associated 5 (209596_at), score: 0.52 MXRA8matrix-remodelling associated 8 (213422_s_at), score: 0.54 NDNnecdin homolog (mouse) (209550_at), score: 0.5 NEFLneurofilament, light polypeptide (221805_at), score: -0.71 NEK7NIMA (never in mitosis gene a)-related kinase 7 (212530_at), score: 0.53 NFASCneurofascin homolog (chicken) (213438_at), score: 0.53 NMUneuromedin U (206023_at), score: -0.65 NOC2Lnucleolar complex associated 2 homolog (S. cerevisiae) (202115_s_at), score: -0.56 NOL12nucleolar protein 12 (219324_at), score: -0.62 NONOnon-POU domain containing, octamer-binding (208698_s_at), score: -0.58 NRGNneurogranin (protein kinase C substrate, RC3) (204081_at), score: -0.65 OASL2'-5'-oligoadenylate synthetase-like (210797_s_at), score: -0.96 PBX1pre-B-cell leukemia homeobox 1 (212148_at), score: 0.54 PCLOpiccolo (presynaptic cytomatrix protein) (213558_at), score: -0.76 PDE10Aphosphodiesterase 10A (205501_at), score: -0.57 PDGFCplatelet derived growth factor C (218718_at), score: 0.55 PILRBpaired immunoglobin-like type 2 receptor beta (220954_s_at), score: -0.64 PQBP1polyglutamine binding protein 1 (214527_s_at), score: -0.61 PSMB8proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (209040_s_at), score: -0.6 PTGER3prostaglandin E receptor 3 (subtype EP3) (213933_at), score: 0.49 QPCTglutaminyl-peptide cyclotransferase (205174_s_at), score: 0.57 RABGAP1LRAB GTPase activating protein 1-like (213982_s_at), score: 0.51 RECKreversion-inducing-cysteine-rich protein with kazal motifs (205407_at), score: 0.61 RGP1RGP1 retrograde golgi transport homolog (S. cerevisiae) (203169_at), score: -0.59 SAMD4Asterile alpha motif domain containing 4A (212845_at), score: 0.56 SERPINB7serpin peptidase inhibitor, clade B (ovalbumin), member 7 (206421_s_at), score: 0.6 SLC12A8solute carrier family 12 (potassium/chloride transporters), member 8 (219874_at), score: -0.57 SLC30A1solute carrier family 30 (zinc transporter), member 1 (212907_at), score: 0.54 SLC4A4solute carrier family 4, sodium bicarbonate cotransporter, member 4 (203908_at), score: 0.53 SLC7A11solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (217678_at), score: -0.6 SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal (209420_s_at), score: 0.48 SNCAsynuclein, alpha (non A4 component of amyloid precursor) (204466_s_at), score: -0.67 SSR3signal sequence receptor, gamma (translocon-associated protein gamma) (217790_s_at), score: 0.49 SSRP1structure specific recognition protein 1 (200956_s_at), score: -0.56 STSsteroid sulfatase (microsomal), isozyme S (203767_s_at), score: 0.49 TBC1D8TBC1 domain family, member 8 (with GRAM domain) (204526_s_at), score: -0.59 TCEAL2transcription elongation factor A (SII)-like 2 (211276_at), score: -0.76 TEKTEK tyrosine kinase, endothelial (206702_at), score: 0.54 TERF1telomeric repeat binding factor (NIMA-interacting) 1 (203448_s_at), score: -0.57 TIMP2TIMP metallopeptidase inhibitor 2 (203167_at), score: 0.66 TKTtransketolase (208699_x_at), score: -0.56 TMEM204transmembrane protein 204 (219315_s_at), score: 0.5 TMEM47transmembrane protein 47 (209656_s_at), score: 0.66 TMOD1tropomodulin 1 (203661_s_at), score: -0.62 TNS1tensin 1 (221748_s_at), score: 0.67 TOB1transducer of ERBB2, 1 (202704_at), score: 0.61 TRIM16tripartite motif-containing 16 (204341_at), score: -0.58 TSPAN13tetraspanin 13 (217979_at), score: 0.59 TSPYL5TSPY-like 5 (213122_at), score: 0.58 TYRP1tyrosinase-related protein 1 (205694_at), score: -0.63 UAP1UDP-N-acteylglucosamine pyrophosphorylase 1 (209340_at), score: 0.5 UBL3ubiquitin-like 3 (201535_at), score: 0.68 UGT1A1UDP glucuronosyltransferase 1 family, polypeptide A1 (207126_x_at), score: -0.87 UGT1A6UDP glucuronosyltransferase 1 family, polypeptide A6 (206094_x_at), score: -0.84 UGT1A9UDP glucuronosyltransferase 1 family, polypeptide A9 (204532_x_at), score: -0.85 VWA5Avon Willebrand factor A domain containing 5A (210102_at), score: -0.57 WDR74WD repeat domain 74 (221712_s_at), score: -0.56 WT1Wilms tumor 1 (206067_s_at), score: -0.76

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
E-GEOD-3407-raw-cel-1437949750.cel 6 4 Cockayne hgu133a CS CSB
E-GEOD-3407-raw-cel-1437949721.cel 5 4 Cockayne hgu133a CS CSB
E-GEOD-3407-raw-cel-1437949579.cel 2 4 Cockayne hgu133a none CSB
E-GEOD-3407-raw-cel-1437949938.cel 8 4 Cockayne hgu133a none CSB
E-GEOD-4219-raw-cel-1311956614.cel 18 7 Sph-mono hgu133plus2 none Sph-mon 1
E-GEOD-4219-raw-cel-1311956138.cel 4 7 Sph-mono hgu133plus2 none Sph-mon 1
E-GEOD-4219-raw-cel-1311956321.cel 9 7 Sph-mono hgu133plus2 none Sph-mon 1
E-GEOD-4219-raw-cel-1311956824.cel 24 7 Sph-mono hgu133plus2 none Sph-mon 1
E-GEOD-4219-raw-cel-1311956178.cel 6 7 Sph-mono hgu133plus2 none Sph-mon 1
E-GEOD-4219-raw-cel-1311956358.cel 10 7 Sph-mono hgu133plus2 none Sph-mon 1

Valid XHTML 1.1 Valid CSS! Best viewed with Firefox

© 2008-2010 Computational Biology Group, Department of Medical Genetics, University of Lausanne, Switzerland