Under-expression is coded with green,
over-expression with red color.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
xenobiotic metabolic process
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
response to xenobiotic stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
response to chemical stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
all
This term is the most general term possible
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
xenobiotic metabolic process
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
lytic vacuole
A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.
lysosome
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
vacuole
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
proteinaceous extracellular matrix
A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
extracellular matrix
A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants).
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
vacuole
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
ABCB1ATP-binding cassette, sub-family B (MDR/TAP), member 1 (209993_at), score: 1 ABCB4ATP-binding cassette, sub-family B (MDR/TAP), member 4 (207819_s_at), score: 0.71 ADORA2Badenosine A2b receptor (205891_at), score: 0.66 AGPSalkylglycerone phosphate synthase (205401_at), score: 0.63 AIM2absent in melanoma 2 (206513_at), score: 0.66 AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase) (206561_s_at), score: 0.89 ANK3ankyrin 3, node of Ranvier (ankyrin G) (206385_s_at), score: 0.62 ANP32Aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A (201043_s_at), score: 0.58 APH1Banterior pharynx defective 1 homolog B (C. elegans) (221036_s_at), score: -0.56 APOBEC3Gapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G (204205_at), score: 0.69 APOL3apolipoprotein L, 3 (221087_s_at), score: 0.57 AQP3aquaporin 3 (Gill blood group) (39248_at), score: 0.58 ARSJarylsulfatase family, member J (219973_at), score: -0.54 BAT1HLA-B associated transcript 1 (200041_s_at), score: 0.57 C10orf116chromosome 10 open reading frame 116 (203571_s_at), score: -0.58 C3orf64chromosome 3 open reading frame 64 (221935_s_at), score: -0.66 C5orf30chromosome 5 open reading frame 30 (221823_at), score: -0.61 CA3carbonic anhydrase III, muscle specific (204865_at), score: 0.58 CCNG1cyclin G1 (208796_s_at), score: -0.52 CD24CD24 molecule (209771_x_at), score: 0.74 CD248CD248 molecule, endosialin (219025_at), score: -0.66 CD81CD81 molecule (200675_at), score: -0.53 CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1) (202284_s_at), score: -0.68 COL11A1collagen, type XI, alpha 1 (37892_at), score: -0.63 CRTAPcartilage associated protein (201380_at), score: -0.59 CRYABcrystallin, alpha B (209283_at), score: -0.58 CTNNBL1catenin, beta like 1 (221021_s_at), score: 0.63 CTSHcathepsin H (202295_s_at), score: 0.58 CTSKcathepsin K (202450_s_at), score: -0.62 DCNdecorin (211896_s_at), score: -0.54 DDAH1dimethylarginine dimethylaminohydrolase 1 (209094_at), score: -0.53 DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 (208151_x_at), score: 0.58 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: 0.8 DHX38DEAH (Asp-Glu-Ala-His) box polypeptide 38 (209178_at), score: 0.61 DIO2deiodinase, iodothyronine, type II (203699_s_at), score: 0.86 DNAJC7DnaJ (Hsp40) homolog, subfamily C, member 7 (202416_at), score: 0.6 DRAP1DR1-associated protein 1 (negative cofactor 2 alpha) (203258_at), score: 0.57 DUSP14dual specificity phosphatase 14 (203367_at), score: -0.57 EMP1epithelial membrane protein 1 (201325_s_at), score: -0.54 EPHB2EPH receptor B2 (209589_s_at), score: 0.76 EPHX1epoxide hydrolase 1, microsomal (xenobiotic) (202017_at), score: 0.57 EWSR1Ewing sarcoma breakpoint region 1 (209214_s_at), score: 0.59 FAM105Afamily with sequence similarity 105, member A (219694_at), score: 0.68 FAM169Afamily with sequence similarity 169, member A (213954_at), score: 0.62 FARP1FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) (201911_s_at), score: -0.52 FAT1FAT tumor suppressor homolog 1 (Drosophila) (201579_at), score: -0.69 FBN2fibrillin 2 (203184_at), score: -0.53 FKBP4FK506 binding protein 4, 59kDa (200895_s_at), score: 0.59 FKBP9FK506 binding protein 9, 63 kDa (212169_at), score: -0.62 FLJ10357hypothetical protein FLJ10357 (58780_s_at), score: -0.54 FOXG1forkhead box G1 (206018_at), score: 0.66 GAGE4G antigen 4 (207086_x_at), score: 0.96 GAGE6G antigen 6 (208155_x_at), score: 0.91 GALCgalactosylceramidase (204417_at), score: -0.49 GALNT6UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) (219956_at), score: -0.5 GAS1growth arrest-specific 1 (204457_s_at), score: -0.52 GAS6growth arrest-specific 6 (202177_at), score: -0.52 GATA3GATA binding protein 3 (209604_s_at), score: 0.82 GCLCglutamate-cysteine ligase, catalytic subunit (202923_s_at), score: 0.62 GLSglutaminase (203159_at), score: -0.63 GNL3guanine nucleotide binding protein-like 3 (nucleolar) (217850_at), score: 0.58 GREM1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) (218469_at), score: -0.67 GSRglutathione reductase (205770_at), score: 0.58 HAS2hyaluronan synthase 2 (206432_at), score: -0.57 HERC5hect domain and RLD 5 (219863_at), score: 0.81 HGSNATheparan-alpha-glucosaminide N-acetyltransferase (218017_s_at), score: -0.65 HIVEP2human immunodeficiency virus type I enhancer binding protein 2 (212642_s_at), score: -0.54 HLA-Bmajor histocompatibility complex, class I, B (211911_x_at), score: 0.58 HRASLSHRAS-like suppressor (219983_at), score: 0.57 HSD17B12hydroxysteroid (17-beta) dehydrogenase 12 (217869_at), score: -0.51 HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 1 (214359_s_at), score: 0.64 HSPB7heat shock 27kDa protein family, member 7 (cardiovascular) (218934_s_at), score: -0.53 IGF2BP3insulin-like growth factor 2 mRNA binding protein 3 (203819_s_at), score: 0.57 IGSF3immunoglobulin superfamily, member 3 (202421_at), score: 0.75 IKIK cytokine, down-regulator of HLA II (200066_at), score: 0.61 IRS2insulin receptor substrate 2 (209185_s_at), score: -0.67 KIAA0802KIAA0802 (213358_at), score: -0.49 KIAA0895KIAA0895 (213424_at), score: 0.6 KIFC1kinesin family member C1 (209680_s_at), score: 0.58 KYNUkynureninase (L-kynurenine hydrolase) (217388_s_at), score: 0.77 LAMB3laminin, beta 3 (209270_at), score: 0.62 LBHlimb bud and heart development homolog (mouse) (221011_s_at), score: -0.51 LDOC1leucine zipper, down-regulated in cancer 1 (204454_at), score: -0.51 LEF1lymphoid enhancer-binding factor 1 (221558_s_at), score: 0.86 LGMNlegumain (201212_at), score: -0.5 LIPAlipase A, lysosomal acid, cholesterol esterase (201847_at), score: -0.58 LOC728855hypothetical LOC728855 (222001_x_at), score: 0.81 LRRC2leucine rich repeat containing 2 (219949_at), score: -0.68 LTBP2latent transforming growth factor beta binding protein 2 (204682_at), score: -0.73 LUMlumican (201744_s_at), score: -0.6 MAGOHmago-nashi homolog, proliferation-associated (Drosophila) (210092_at), score: 0.63 MAN2A1mannosidase, alpha, class 2A, member 1 (205105_at), score: -0.66 MARCH2membrane-associated ring finger (C3HC4) 2 (210075_at), score: -0.56 MARK1MAP/microtubule affinity-regulating kinase 1 (221047_s_at), score: 0.61 MFAP5microfibrillar associated protein 5 (213764_s_at), score: -0.6 MOXD1monooxygenase, DBH-like 1 (209708_at), score: -0.67 MRC2mannose receptor, C type 2 (37408_at), score: -0.6 MSCmusculin (activated B-cell factor-1) (209928_s_at), score: 0.58 MXRA5matrix-remodelling associated 5 (209596_at), score: -0.59 MXRA8matrix-remodelling associated 8 (213422_s_at), score: -0.61 NASPnuclear autoantigenic sperm protein (histone-binding) (201970_s_at), score: 0.57 NDNnecdin homolog (mouse) (209550_at), score: -0.58 NEFLneurofilament, light polypeptide (221805_at), score: 0.71 NEK7NIMA (never in mitosis gene a)-related kinase 7 (212530_at), score: -0.59 NFASCneurofascin homolog (chicken) (213438_at), score: -0.56 NGDNneuroguidin, EIF4E binding protein (213794_s_at), score: 0.57 NMUneuromedin U (206023_at), score: 0.68 NOC2Lnucleolar complex associated 2 homolog (S. cerevisiae) (202115_s_at), score: 0.6 NOL12nucleolar protein 12 (219324_at), score: 0.66 NONOnon-POU domain containing, octamer-binding (208698_s_at), score: 0.6 NRGNneurogranin (protein kinase C substrate, RC3) (204081_at), score: 0.65 OASL2'-5'-oligoadenylate synthetase-like (210797_s_at), score: 0.96 OLFML3olfactomedin-like 3 (218162_at), score: -0.5 PBX1pre-B-cell leukemia homeobox 1 (212148_at), score: -0.6 PCLOpiccolo (presynaptic cytomatrix protein) (213558_at), score: 0.84 PDE10Aphosphodiesterase 10A (205501_at), score: 0.58 PDGFCplatelet derived growth factor C (218718_at), score: -0.59 PHF11PHD finger protein 11 (221816_s_at), score: -0.49 PILRBpaired immunoglobin-like type 2 receptor beta (220954_s_at), score: 0.65 PIRpirin (iron-binding nuclear protein) (207469_s_at), score: 0.62 PLCB1phospholipase C, beta 1 (phosphoinositide-specific) (213222_at), score: -0.51 PLK2polo-like kinase 2 (Drosophila) (201939_at), score: 0.59 POLR3Gpolymerase (RNA) III (DNA directed) polypeptide G (32kD) (206653_at), score: 0.6 PPIHpeptidylprolyl isomerase H (cyclophilin H) (204228_at), score: 0.59 PPP2R2Bprotein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform (213849_s_at), score: 0.57 PQBP1polyglutamine binding protein 1 (214527_s_at), score: 0.66 PRRX1paired related homeobox 1 (205991_s_at), score: -0.5 PSMB8proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (209040_s_at), score: 0.68 PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 3 (201267_s_at), score: 0.57 PTGER3prostaglandin E receptor 3 (subtype EP3) (213933_at), score: -0.5 QPCTglutaminyl-peptide cyclotransferase (205174_s_at), score: -0.66 RARRES3retinoic acid receptor responder (tazarotene induced) 3 (204070_at), score: 0.64 RECKreversion-inducing-cysteine-rich protein with kazal motifs (205407_at), score: -0.68 RGP1RGP1 retrograde golgi transport homolog (S. cerevisiae) (203169_at), score: 0.66 RPP14ribonuclease P/MRP 14kDa subunit (204245_s_at), score: 0.59 SAMD4Asterile alpha motif domain containing 4A (212845_at), score: -0.65 SC65synaptonemal complex protein SC65 (204078_at), score: -0.49 SERPINB7serpin peptidase inhibitor, clade B (ovalbumin), member 7 (206421_s_at), score: -0.64 SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (212190_at), score: -0.52 SERPINF1serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (202283_at), score: -0.52 SGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein) (213543_at), score: -0.49 SHFM1split hand/foot malformation (ectrodactyly) type 1 (202276_at), score: 0.59 SLC12A8solute carrier family 12 (potassium/chloride transporters), member 8 (219874_at), score: 0.67 SLC30A1solute carrier family 30 (zinc transporter), member 1 (212907_at), score: -0.62 SLC4A4solute carrier family 4, sodium bicarbonate cotransporter, member 4 (203908_at), score: -0.54 SLC7A11solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (217678_at), score: 0.68 SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal (209420_s_at), score: -0.49 SNCAsynuclein, alpha (non A4 component of amyloid precursor) (204466_s_at), score: 0.6 SSR3signal sequence receptor, gamma (translocon-associated protein gamma) (217790_s_at), score: -0.52 SSRP1structure specific recognition protein 1 (200956_s_at), score: 0.62 STSsteroid sulfatase (microsomal), isozyme S (203767_s_at), score: -0.53 TBC1D3TBC1 domain family, member 3 (209403_at), score: 0.57 TBC1D8TBC1 domain family, member 8 (with GRAM domain) (204526_s_at), score: 0.61 TCEAL2transcription elongation factor A (SII)-like 2 (211276_at), score: 0.76 TEKTEK tyrosine kinase, endothelial (206702_at), score: -0.54 TERF1telomeric repeat binding factor (NIMA-interacting) 1 (203448_s_at), score: 0.6 TESK1testis-specific kinase 1 (204106_at), score: -0.5 TIMP2TIMP metallopeptidase inhibitor 2 (203167_at), score: -0.73 TKTtransketolase (208699_x_at), score: 0.65 TMEM204transmembrane protein 204 (219315_s_at), score: -0.57 TMEM47transmembrane protein 47 (209656_s_at), score: -0.69 TMOD1tropomodulin 1 (203661_s_at), score: 0.64 TNS1tensin 1 (221748_s_at), score: -0.78 TOB1transducer of ERBB2, 1 (202704_at), score: -0.66 TPD52tumor protein D52 (201690_s_at), score: 0.6 TRIM16tripartite motif-containing 16 (204341_at), score: 0.64 TSPAN13tetraspanin 13 (217979_at), score: -0.66 TSPYL1TSPY-like 1 (221493_at), score: -0.51 TSPYL5TSPY-like 5 (213122_at), score: -0.68 TYRP1tyrosinase-related protein 1 (205694_at), score: 0.68 UAP1UDP-N-acteylglucosamine pyrophosphorylase 1 (209340_at), score: -0.54 UBL3ubiquitin-like 3 (201535_at), score: -0.72 UGT1A1UDP glucuronosyltransferase 1 family, polypeptide A1 (207126_x_at), score: 0.88 UGT1A6UDP glucuronosyltransferase 1 family, polypeptide A6 (206094_x_at), score: 0.84 UGT1A9UDP glucuronosyltransferase 1 family, polypeptide A9 (204532_x_at), score: 0.85 VWA5Avon Willebrand factor A domain containing 5A (210102_at), score: 0.57 WDR74WD repeat domain 74 (221712_s_at), score: 0.59 WT1Wilms tumor 1 (206067_s_at), score: 0.83 YPEL5yippee-like 5 (Drosophila) (217783_s_at), score: -0.53
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-GEOD-4219-raw-cel-1311956824.cel | 24 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956178.cel | 6 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956358.cel | 10 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956418.cel | 13 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956457.cel | 14 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956138.cel | 4 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956321.cel | 9 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956614.cel | 18 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-3407-raw-cel-1437949938.cel | 8 | 4 | Cockayne | hgu133a | none | CSB |
| E-GEOD-3407-raw-cel-1437949579.cel | 2 | 4 | Cockayne | hgu133a | none | CSB |
| E-GEOD-3407-raw-cel-1437949721.cel | 5 | 4 | Cockayne | hgu133a | CS | CSB |
| E-GEOD-3407-raw-cel-1437949750.cel | 6 | 4 | Cockayne | hgu133a | CS | CSB |
