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system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell surface receptor linked signal transduction

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

G-protein coupled receptor protein signaling pathway

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

sensory perception

The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cognition

The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

G-protein coupled receptor activity

A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

Id	Pvalue	ExpCount	Count	Size	Term
GO:0032501	2.583e-05	47.66	81 ABCG1, ADORA1, ADORA2A, AIPL1, ALMS1, BAIAP3, BCL2L11, CA4, CATSPER2, COX5B, CSPG5, CTSE, CYLC1, CYP11B1, CYP1A2, DAZ1, DAZ3, DAZ4, DIP2A, DLX4, DUOX1, EDA, ERBB4, F11, FCER1G, FGF12, GNRHR, GP6, GRM6, HAND1, HBB, HTN1, HTR1E, IFNG, INSR, KLF1, KRT2, LHX3, LY6H, MCL1, MEP1B, MFNG, MOBP, MOG, MYH15, MYO1A, NHLH2, NTRK2, OR2B2, OR2W1, OR7E24, OVOL2, PBX2, PGF, POGZ, POU4F1, POU4F2, PPARGC1A, REG3A, RET, RPGRIP1, RRH, SERF1B, SFN, SFTPB, SH3GL3, SLC15A1, SLC17A6, SPN, TAC1, TAS2R16, TAS2R9, TBX21, TBX6, TIMM8A, TP63, TRPV1, UTF1, XRCC2, ZNF160, ZNF287	1648	multicellular organismal process
GO:0007600	5.033e-04	5.119	18 ADORA2A, AIPL1, ALMS1, CA4, GRM6, MYO1A, OR2B2, OR2W1, OR7E24, POU4F1, POU4F2, RPGRIP1, RRH, TAC1, TAS2R16, TAS2R9, TIMM8A, TRPV1	177	sensory perception
GO:0007186	2.002e-03	6.854	20 ADORA1, ADORA2A, CCR9, GNG4, GNRHR, GRM6, HTR1E, INSR, NPY2R, OR2B2, OR2W1, OR7E24, P2RY4, RRH, TAAR2, TAC1, TACR1, TAS2R16, TAS2R9, TSHB	237	G-protein coupled receptor protein signaling pathway
GO:0050890	3.878e-03	6.073	18 ADORA2A, AIPL1, ALMS1, CA4, GRM6, MYO1A, OR2B2, OR2W1, OR7E24, POU4F1, POU4F2, RPGRIP1, RRH, TAC1, TAS2R16, TAS2R9, TIMM8A, TRPV1	210	cognition
GO:0050877	6.914e-03	9.486	23 ADORA2A, AIPL1, ALMS1, BAIAP3, CA4, GRM6, HTR1E, IFNG, MYO1A, NTRK2, OR2B2, OR2W1, OR7E24, POU4F1, POU4F2, RPGRIP1, RRH, SLC17A6, TAC1, TAS2R16, TAS2R9, TIMM8A, TRPV1	328	neurological system process
GO:0050896	1.112e-02	39.04	61 ABCG1, ADORA1, ADORA2A, AIPL1, ALMS1, CA4, CCR9, CIRBP, CLEC4E, CYP11B1, CYP1A2, DUOX1, EDA, F11, FCAR, FCER1G, GNG4, GP6, GRM6, HTN1, IFNA16, IFNA5, IFNG, ITK, KMO, LAX1, MAP2K7, MAP3K9, MASP2, MEFV, MNDA, NHLH2, NPY2R, NTRK2, OR2B2, OR2W1, OR7E24, PLA2G7, PMS2L2, POU4F1, PPARGC1A, REG3A, RPGRIP1, SCN11A, SERPINB13, SFN, SLC11A1, SLC30A5, SPG21, SPN, TAC1, TACR1, TAS2R16, TAS2R9, TBX21, TNFSF10, TP63, TRPV1, TSHB, UGT2B28, XRCC2	1350	response to stimulus
GO:0006968	1.359e-02	0.5495	5 ADORA2A, CCR9, ITK, MNDA, SPN	19	cellular defense response
GO:0007606	3.241e-02	0.6941	5 OR2B2, OR2W1, OR7E24, TAS2R16, TAS2R9	24	sensory perception of chemical stimulus
GO:0003008	3.725e-02	13.19	26 ADORA2A, AIPL1, ALMS1, BAIAP3, CA4, CYP11B1, GRM6, HBB, HTR1E, IFNG, MYH15, MYO1A, NTRK2, OR2B2, OR2W1, OR7E24, POU4F1, POU4F2, RPGRIP1, RRH, SLC17A6, TAC1, TAS2R16, TAS2R9, TIMM8A, TRPV1	456	system process
GO:0007166	4.352e-02	20.19	35 ADORA1, ADORA2A, BCL9, CCR9, DUOX1, ERBB4, FCER1G, FGFR2, GNG4, GNRHR, GP6, GRM6, HTR1E, IFNG, IL2RB, INSR, NPY2R, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, RRH, SIRPB1, SPG21, SPN, TAAR2, TAC1, TACR1, TAS2R16, TAS2R9, TP63, TRPV1, TSHB, WNT6	698	cell surface receptor linked signal transduction
GO:0048304	4.418e-02	0.05784	2 IFNG, TBX21	2	positive regulation of isotype switching to IgG isotypes

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005887	2.153e-04	16.2	36 ABCG1, ADORA1, ADORA2A, CCR9, CEACAM5, CSPG5, ERBB4, FCAR, FCER1G, FOLH1, GNRHR, GP6, GRM6, HTR1E, IL2RB, INSR, KCNJ14, MEP1B, NPY2R, NTRK2, P2RY4, RRH, SCN11A, SIRPB1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC30A5, SLC6A14, SPN, TACR1, TNFRSF9, TNFSF10, TRPV1, TSPAN15	549	integral to plasma membrane
GO:0031226	2.599e-04	16.35	36 ABCG1, ADORA1, ADORA2A, CCR9, CEACAM5, CSPG5, ERBB4, FCAR, FCER1G, FOLH1, GNRHR, GP6, GRM6, HTR1E, IL2RB, INSR, KCNJ14, MEP1B, NPY2R, NTRK2, P2RY4, RRH, SCN11A, SIRPB1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC30A5, SLC6A14, SPN, TACR1, TNFRSF9, TNFSF10, TRPV1, TSPAN15	554	intrinsic to plasma membrane
GO:0005576	6.186e-04	20.66	41 ADAMDEC1, ADAMTSL3, CHI3L1, EDA, F11, FCAR, FGF12, FGFR2, FGL1, GZMM, HTN1, IFNA16, IFNA5, IFNG, LAMB4, MASP2, MEP1B, MFNG, MMRN2, MSTP9, MUC5AC, PECAM1, PGF, PLA2G7, PLGLB1, PRB3, PROL1, REG3A, RLN1, SERPINA7, SFN, SFTPB, SPARCL1, SPINLW1, SPN, ST3GAL2, TAC1, TNFSF10, TSHB, WNT6, ZPBP	700	extracellular region
GO:0005886	1.088e-03	42.59	68 ABCG1, ADORA1, ADORA2A, ATP5O, BCL2L11, CA4, CATSPER2, CCR9, CD53, CEACAM5, CLDN10, CNKSR2, CSPG5, DUOX1, EDA, ERBB4, FCAR, FCER1G, FCGR2A, FGFR2, FOLH1, G3BP1, GNG4, GNRHR, GP6, GRM6, HTR1E, IL2RB, INSR, ITK, KCNJ14, LAX1, LY6H, MEP1B, MOG, MYO1A, NPY2R, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, PECAM1, RAB26, RET, RIMS2, RRH, SCN11A, SIRPB1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC30A5, SLC6A14, SPAM1, SPN, STXBP5L, TAAR2, TACR1, TAS2R16, TNFRSF9, TNFSF10, TP63, TRPV1, TSPAN15, VEZT	1443	plasma membrane
GO:0044459	4.257e-03	25.83	45 ABCG1, ADORA1, ADORA2A, CCR9, CEACAM5, CLDN10, CSPG5, DUOX1, ERBB4, FCAR, FCER1G, FOLH1, GNG4, GNRHR, GP6, GRM6, HTR1E, IL2RB, INSR, KCNJ14, MEP1B, MYO1A, NPY2R, NTRK2, P2RY4, RIMS2, RRH, SCN11A, SIRPB1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC30A5, SLC6A14, SPN, TACR1, TAS2R16, TNFRSF9, TNFSF10, TP63, TRPV1, TSPAN15, VEZT	875	plasma membrane part
GO:0005615	2.445e-02	7.261	17 CHI3L1, F11, FGF12, FGL1, IFNA16, IFNA5, IFNG, MEP1B, MFNG, PECAM1, REG3A, SERPINA7, SFN, SFTPB, SPN, TAC1, TNFSF10	246	extracellular space
GO:0044421	2.631e-02	11.42	23 ADAMTSL3, CHI3L1, F11, FGF12, FGL1, IFNA16, IFNA5, IFNG, LAMB4, MEP1B, MFNG, MMRN2, MUC5AC, PECAM1, REG3A, SERPINA7, SFN, SFTPB, SPARCL1, SPN, TAC1, TNFSF10, WNT6	387	extracellular region part

Id	Pvalue	ExpCount	Count	Size	Term
GO:0004930	4.416e-04	3.88	16 ADORA1, ADORA2A, CCR9, GNRHR, GRM6, HTR1E, NPY2R, OR2B2, OR2W1, OR7E24, P2RY4, RRH, TAAR2, TACR1, TAS2R16, TAS2R9	137	G-protein coupled receptor activity
GO:0004888	6.569e-04	9.46	26 ADORA1, ADORA2A, CCR9, ERBB4, FCER1G, FGFR2, GNRHR, GP6, GRM6, HTR1E, IL2RB, INSR, NPY2R, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, RET, RRH, SCARF1, SPN, TAAR2, TACR1, TAS2R16, TAS2R9	334	transmembrane receptor activity
GO:0004497	5.684e-03	0.963	7 CYP11B1, CYP1A2, CYP2B6, CYP2C9, CYP3A4, DOHH, KMO	34	monooxygenase activity
GO:0004872	2.120e-02	15.1	30 ADORA1, ADORA2A, CCR9, ERBB4, FCAR, FCER1G, FCGR2A, FGFR2, GNRHR, GP6, GRM6, HTR1E, IL2RB, INSR, NPY2R, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, RET, RRH, SCARF1, SPN, TAAR2, TACR1, TAS2R16, TAS2R9, TNFRSF9, TNPO3	533	receptor activity
GO:0020037	2.329e-02	1.275	7 CYP11B1, CYP1A2, CYP2B6, CYP2C9, CYP3A4, DUOX1, HBB	45	heme binding
GO:0046906	2.329e-02	1.275	7 CYP11B1, CYP1A2, CYP2B6, CYP2C9, CYP3A4, DUOX1, HBB	45	tetrapyrrole binding
GO:0016712	3.429e-02	0.1699	3 CYP1A2, CYP2B6, CYP3A4	6	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019865	3.429e-02	0.1699	3 FCAR, FCER1G, FCGR2A	6	immunoglobulin binding
GO:0001608	4.931e-02	0.1983	3 ADORA1, ADORA2A, P2RY4	7	nucleotide receptor activity, G-protein coupled
GO:0045028	4.931e-02	0.1983	3 ADORA1, ADORA2A, P2RY4	7	purinergic nucleotide receptor activity, G-protein coupled

Id	Pvalue	ExpCount	Count	Size	Term
04080	2.261e-03	2.405	11 ADORA1, ADORA2A, GNRHR, GRM6, HTR1E, NPY2R, P2RY4, TAAR2, TACR1, TRPV1, TSHB	83	Neuroactive ligand-receptor interaction
00830	2.715e-02	0.6665	5 CYP1A2, CYP2B6, CYP2C9, CYP3A4, UGT2B28	23	Retinol metabolism

No enriched terms

No enriched terms

Entrez genes

ABCG1ATP-binding cassette, sub-family G (WHITE), member 1 (204567_s_at), score: 0.68 ACOT11acyl-CoA thioesterase 11 (216103_at), score: 0.85 ADAMDEC1ADAM-like, decysin 1 (206134_at), score: 0.68 ADAMTSL3ADAMTS-like 3 (213974_at), score: 0.67 ADORA1adenosine A1 receptor (216220_s_at), score: 0.78 ADORA2Aadenosine A2a receptor (205013_s_at), score: 0.76 AGMATagmatine ureohydrolase (agmatinase) (219792_at), score: 0.65 AIPL1aryl hydrocarbon receptor interacting protein-like 1 (219977_at), score: 0.69 ALDOAP2aldolase A, fructose-bisphosphate pseudogene 2 (211617_at), score: 0.87 ALMS1Alstrom syndrome 1 (214707_x_at), score: 0.84 APBB2amyloid beta (A4) precursor protein-binding, family B, member 2 (212972_x_at), score: 0.74 ARAP2ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 (214102_at), score: 0.71 ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (216954_x_at), score: 0.78 BACH2BTB and CNC homology 1, basic leucine zipper transcription factor 2 (221234_s_at), score: 0.63 BAIAP3BAI1-associated protein 3 (216356_x_at), score: 0.69 BCL2L11BCL2-like 11 (apoptosis facilitator) (222343_at), score: 0.75 BCL9B-cell CLL/lymphoma 9 (204129_at), score: 0.76 BTF3L2basic transcription factor 3, like 2 (217461_x_at), score: 0.63 C10orf110chromosome 10 open reading frame 110 (220703_at), score: 0.76 C11orf1chromosome 11 open reading frame 1 (218925_s_at), score: 0.65 C17orf86chromosome 17 open reading frame 86 (221621_at), score: 0.79 C1orf69chromosome 1 open reading frame 69 (215490_at), score: 0.69 C3orf51chromosome 3 open reading frame 51 (208247_at), score: 0.66 C6orf162chromosome 6 open reading frame 162 (213314_at), score: 0.63 C7orf28Achromosome 7 open reading frame 28A (201974_s_at), score: 0.81 C8orf60chromosome 8 open reading frame 60 (220712_at), score: 0.67 CA4carbonic anhydrase IV (206209_s_at), score: 0.65 CADM4cell adhesion molecule 4 (222293_at), score: 0.74 CATSPER2cation channel, sperm associated 2 (217588_at), score: 0.79 CCR9chemokine (C-C motif) receptor 9 (207445_s_at), score: 0.77 CD53CD53 molecule (203416_at), score: 0.8 CDC14ACDC14 cell division cycle 14 homolog A (S. cerevisiae) (205288_at), score: 0.66 CDR1cerebellar degeneration-related protein 1, 34kDa (207276_at), score: 0.81 CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5 (201884_at), score: 0.83 CEP27centrosomal protein 27kDa (220071_x_at), score: 0.84 CGGBP1CGG triplet repeat binding protein 1 (214050_at), score: 0.93 CHD2chromodomain helicase DNA binding protein 2 (203461_at), score: 0.65 CHI3L1chitinase 3-like 1 (cartilage glycoprotein-39) (209395_at), score: 0.74 CHN2chimerin (chimaerin) 2 (207486_x_at), score: 0.81 CIRBPcold inducible RNA binding protein (200811_at), score: 0.71 CLDN10claudin 10 (205328_at), score: 0.71 CLEC4EC-type lectin domain family 4, member E (219859_at), score: 0.77 CNKSR2connector enhancer of kinase suppressor of Ras 2 (206731_at), score: 0.69 COX5Bcytochrome c oxidase subunit Vb (213736_at), score: 0.69 CSPG5chondroitin sulfate proteoglycan 5 (neuroglycan C) (39966_at), score: 0.66 CTSEcathepsin E (205927_s_at), score: 0.68 CTTNBP2NLCTTNBP2 N-terminal like (214731_at), score: 0.73 CXorf21chromosome X open reading frame 21 (220252_x_at), score: 0.75 CYLC1cylicin, basic protein of sperm head cytoskeleton 1 (216809_at), score: 0.82 CYP11B1cytochrome P450, family 11, subfamily B, polypeptide 1 (214610_at), score: 0.79 CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 2 (207608_x_at), score: 0.68 CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 6 (217133_x_at), score: 0.8 CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 9 (214421_x_at), score: 0.86 CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 4 (205998_x_at), score: 0.82 DAPP1dual adaptor of phosphotyrosine and 3-phosphoinositides (219290_x_at), score: 0.86 DAZ1deleted in azoospermia 1 (216922_x_at), score: 0.87 DAZ3deleted in azoospermia 3 (208281_x_at), score: 0.82 DAZ4deleted in azoospermia 4 (216351_x_at), score: 0.86 DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila) (215529_x_at), score: 0.76 DKFZp686O1327hypothetical gene supported by BC043549; BX648102 (216877_at), score: 0.86 DLX4distal-less homeobox 4 (208216_at), score: 0.76 DNAH7dynein, axonemal, heavy chain 7 (214222_at), score: 0.66 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: 0.67 DNM3dynamin 3 (209839_at), score: 0.65 DOHHdeoxyhypusine hydroxylase/monooxygenase (208141_s_at), score: 0.63 DTNBdystrobrevin, beta (215295_at), score: 0.64 DUOX1dual oxidase 1 (215800_at), score: 0.75 EDAectodysplasin A (211130_x_at), score: 0.66 EEF1Deukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) (214395_x_at), score: 0.67 ELK4ELK4, ETS-domain protein (SRF accessory protein 1) (206919_at), score: 0.84 ELL3elongation factor RNA polymerase II-like 3 (219517_at), score: 0.67 EPAGearly lymphoid activation protein (217050_at), score: 0.92 EPB41L1erythrocyte membrane protein band 4.1-like 1 (212339_at), score: 0.72 ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (214053_at), score: 0.72 F11coagulation factor XI (206610_s_at), score: 0.65 FAM106Afamily with sequence similarity 106, member A (220575_at), score: 0.69 FAM75A3family with sequence similarity 75, member A3 (215935_at), score: 0.85 FBXO41F-box protein 41 (44040_at), score: 0.9 FBXW12F-box and WD repeat domain containing 12 (215600_x_at), score: 0.69 FCARFc fragment of IgA, receptor for (211305_x_at), score: 0.68 FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide (204232_at), score: 0.73 FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32) (203561_at), score: 0.65 FETUBfetuin B (214417_s_at), score: 0.64 FGF12fibroblast growth factor 12 (207501_s_at), score: 0.65 FGFR2fibroblast growth factor receptor 2 (208229_at), score: 0.66 FGL1fibrinogen-like 1 (205305_at), score: 0.76 FLJ11292hypothetical protein FLJ11292 (220828_s_at), score: 0.85 FLJ21369hypothetical protein FLJ21369 (220401_at), score: 0.75 FLJ23172hypothetical LOC389177 (217016_x_at), score: 0.9 FOLH1folate hydrolase (prostate-specific membrane antigen) 1 (217487_x_at), score: 0.85 FUT2fucosyltransferase 2 (secretor status included) (210608_s_at), score: 0.76 FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (214088_s_at), score: 0.77 G3BP1GTPase activating protein (SH3 domain) binding protein 1 (222187_x_at), score: 0.9 GK2glycerol kinase 2 (215430_at), score: 0.87 GNG4guanine nucleotide binding protein (G protein), gamma 4 (205184_at), score: 0.7 GNRHRgonadotropin-releasing hormone receptor (216341_s_at), score: 0.71 GP6glycoprotein VI (platelet) (220336_s_at), score: 0.67 GRHL2grainyhead-like 2 (Drosophila) (219388_at), score: 0.88 GRM6glutamate receptor, metabotropic 6 (208035_at), score: 0.75 GZMMgranzyme M (lymphocyte met-ase 1) (207460_at), score: 0.78 HAND1heart and neural crest derivatives expressed 1 (220138_at), score: 0.82 HAO2hydroxyacid oxidase 2 (long chain) (220801_s_at), score: 0.86 HBBhemoglobin, beta (211696_x_at), score: 0.79 HCG2P7HLA complex group 2 pseudogene 7 (216229_x_at), score: 0.79 HIST1H4Dhistone cluster 1, H4d (208076_at), score: 0.7 HTN1histatin 1 (206639_x_at), score: 0.65 HTR1E5-hydroxytryptamine (serotonin) receptor 1E (207404_s_at), score: 0.71 IBD12Inflammatory bowel disease 12 (215373_x_at), score: 0.83 IFNA16interferon, alpha 16 (208448_x_at), score: 0.74 IFNA5interferon, alpha 5 (214569_at), score: 0.64 IFNGinterferon, gamma (210354_at), score: 0.68 IL2RBinterleukin 2 receptor, beta (205291_at), score: 0.63 INE1inactivation escape 1 (non-protein coding) (207252_at), score: 0.69 INSRinsulin receptor (213792_s_at), score: 0.64 ITKIL2-inducible T-cell kinase (211339_s_at), score: 0.64 KCNJ14potassium inwardly-rectifying channel, subfamily J, member 14 (220776_at), score: 0.81 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: 0.86 KIAA0748KIAA0748 (219724_s_at), score: 0.64 KIAA0894KIAA0894 protein (207436_x_at), score: 0.63 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: 0.68 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (205307_s_at), score: 0.67 KRT2keratin 2 (207908_at), score: 0.65 LAMB4laminin, beta 4 (215516_at), score: 0.72 LAX1lymphocyte transmembrane adaptor 1 (207734_at), score: 0.76 LGALS14lectin, galactoside-binding, soluble, 14 (220158_at), score: 0.63 LHX3LIM homeobox 3 (221670_s_at), score: 0.72 LOC100128701heterogeneous nuclear ribonucleoprotein A1-like 2 pseudogene (216497_at), score: 0.72 LOC100128836similar to heterogeneous nuclear ribonucleoprotein A1 (217353_at), score: 0.71 LOC100129624hypothetical LOC100129624 (210748_at), score: 0.79 LOC100130233similar to NPM1 protein (216387_x_at), score: 0.84 LOC100132247similar to Uncharacterized protein KIAA0220 (215002_at), score: 0.73 LOC100134401hypothetical protein LOC100134401 (213605_s_at), score: 0.77 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: 0.66 LOC23117PI-3-kinase-related kinase SMG-1 isoform 1 homolog (211996_s_at), score: 0.79 LOC282997hypothetical protein LOC282997 (222307_at), score: 0.63 LOC284440hypothetical LOC284440 (216126_at), score: 0.65 LOC440345hypothetical protein LOC440345 (214984_at), score: 0.7 LOC51152melanoma antigen (220771_at), score: 0.66 LOC647070hypothetical LOC647070 (215467_x_at), score: 0.74 LOC728844hypothetical LOC728844 (222040_at), score: 0.75 LOC730227hypothetical protein LOC730227 (215756_at), score: 0.63 LOC91316glucuronidase, beta/ immunoglobulin lambda-like polypeptide 1 pseudogene (215816_at), score: 0.72 LY6Hlymphocyte antigen 6 complex, locus H (206773_at), score: 0.66 MAP2K7mitogen-activated protein kinase kinase 7 (216206_x_at), score: 0.77 MAP3K9mitogen-activated protein kinase kinase kinase 9 (213927_at), score: 0.82 MASP2mannan-binding lectin serine peptidase 2 (207041_at), score: 0.69 MCL1myeloid cell leukemia sequence 1 (BCL2-related) (214057_at), score: 0.68 MEFVMediterranean fever (208262_x_at), score: 0.83 MEP1Bmeprin A, beta (207251_at), score: 0.68 METAP2methionyl aminopeptidase 2 (202015_x_at), score: 0.87 METTL7Amethyltransferase like 7A (211424_x_at), score: 0.97 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: 0.68 MFSD11major facilitator superfamily domain containing 11 (221192_x_at), score: 0.76 MKRN1makorin ring finger protein 1 (208082_x_at), score: 0.88 MLLT10myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (216506_x_at), score: 0.65 MMRN2multimerin 2 (219091_s_at), score: 0.64 MNDAmyeloid cell nuclear differentiation antigen (204959_at), score: 0.78 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: 0.73 MOGmyelin oligodendrocyte glycoprotein (214650_x_at), score: 0.8 MRPL44mitochondrial ribosomal protein L44 (218202_x_at), score: 0.74 MSTP9macrophage stimulating, pseudogene 9 (213382_at), score: 0.77 MUC5ACmucin 5AC, oligomeric mucus/gel-forming (217182_at), score: 0.74 MYCL1v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) (214058_at), score: 0.65 MYH15myosin, heavy chain 15 (215331_at), score: 0.73 MYO1Amyosin IA (211916_s_at), score: 0.63 MYO5Cmyosin VC (218966_at), score: 0.65 NACA2nascent polypeptide-associated complex alpha subunit 2 (222224_at), score: 0.69 NAG18NAG18 mRNA (210496_at), score: 0.76 NCRNA00092non-protein coding RNA 92 (215861_at), score: 0.89 NCRNA00093non-protein coding RNA 93 (210723_x_at), score: 0.9 NHLH2nescient helix loop helix 2 (215228_at), score: 0.64 NPIPL2nuclear pore complex interacting protein-like 2 (221992_at), score: 0.79 NPY2Rneuropeptide Y receptor Y2 (210730_s_at), score: 0.74 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: 0.79 OR2B2olfactory receptor, family 2, subfamily B, member 2 (216408_at), score: 0.74 OR2W1olfactory receptor, family 2, subfamily W, member 1 (221451_s_at), score: 0.66 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: 0.7 OVOL2ovo-like 2 (Drosophila) (211778_s_at), score: 0.65 P2RY4pyrimidinergic receptor P2Y, G-protein coupled, 4 (221466_at), score: 0.64 PBX2pre-B-cell leukemia homeobox 2 (202876_s_at), score: 0.66 PDE4Cphosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila) (206792_x_at), score: 0.73 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: 0.83 PEG3paternally expressed 3 (209242_at), score: 0.7 PELI2pellino homolog 2 (Drosophila) (219132_at), score: 0.64 PGFplacental growth factor (215179_x_at), score: 0.67 PLA2G7phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (206214_at), score: 0.68 PLGLB1plasminogen-like B1 (214415_at), score: 0.65 PMS2L2postmeiotic segregation increased 2-like 2 pseudogene (215410_at), score: 0.64 POGZpogo transposable element with ZNF domain (215281_x_at), score: 0.89 POLR1Bpolymerase (RNA) I polypeptide B, 128kDa (220113_x_at), score: 0.67 POM121L9PPOM121 membrane glycoprotein-like 9 (rat) pseudogene (222253_s_at), score: 0.81 POU4F1POU class 4 homeobox 1 (206940_s_at), score: 0.75 POU4F2POU class 4 homeobox 2 (207725_at), score: 0.69 PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha (219195_at), score: 0.83 PPP1R14Dprotein phosphatase 1, regulatory (inhibitor) subunit 14D (220082_at), score: 0.76 PRB3proline-rich protein BstNI subfamily 3 (206998_x_at), score: 0.68 PRINSpsoriasis associated RNA induced by stress (non-protein coding) (216051_x_at), score: 0.99 PROL1proline rich, lacrimal 1 (208004_at), score: 0.75 RAB26RAB26, member RAS oncogene family (50965_at), score: 0.69 RBMX2RNA binding motif protein, X-linked 2 (204098_at), score: 0.63 REG3Aregenerating islet-derived 3 alpha (205815_at), score: 0.64 RETret proto-oncogene (205879_x_at), score: 0.66 RIMS2regulating synaptic membrane exocytosis 2 (215478_at), score: 0.77 RLN1relaxin 1 (211753_s_at), score: 0.75 RP11-35N6.1plasticity related gene 3 (219732_at), score: 0.69 RP3-377H14.5hypothetical LOC285830 (222279_at), score: 0.85 RP5-886K2.1neuronal thread protein AD7c-NTP (207953_at), score: 0.87 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: 0.73 RPL14ribosomal protein L14 (219138_at), score: 0.65 RPL21P37ribosomal protein L21 pseudogene 37 (216479_at), score: 0.95 RPL23AP32ribosomal protein L23a pseudogene 32 (207283_at), score: 0.79 RPL35Aribosomal protein L35a (215208_x_at), score: 0.86 RPL37Aribosomal protein L37a (214041_x_at), score: 0.69 RPLP2ribosomal protein, large, P2 (200908_s_at), score: 0.73 RPS10P3ribosomal protein S10 pseudogene 3 (217336_at), score: 0.76 RPS3AP47ribosomal protein S3a pseudogene 47 (216823_at), score: 0.71 RRHretinal pigment epithelium-derived rhodopsin homolog (208314_at), score: 0.7 S100A14S100 calcium binding protein A14 (218677_at), score: 0.64 SCARF1scavenger receptor class F, member 1 (206995_x_at), score: 0.8 SCN11Asodium channel, voltage-gated, type XI, alpha subunit (220791_x_at), score: 0.81 SERF1Bsmall EDRK-rich factor 1B (centromeric) (219982_s_at), score: 0.68 SERPINA7serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (206386_at), score: 0.79 SERPINB13serpin peptidase inhibitor, clade B (ovalbumin), member 13 (211362_s_at), score: 0.77 SFNstratifin (33322_i_at), score: 0.75 SFRS11splicing factor, arginine/serine-rich 11 (213742_at), score: 0.63 SFTPBsurfactant protein B (214354_x_at), score: 0.88 SH3BP2SH3-domain binding protein 2 (217257_at), score: 0.84 SH3GL3SH3-domain GRB2-like 3 (211565_at), score: 0.68 SIRPB1signal-regulatory protein beta 1 (206934_at), score: 0.71 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (207185_at), score: 0.84 SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (217473_x_at), score: 0.68 SLC12A3solute carrier family 12 (sodium/chloride transporters), member 3 (215274_at), score: 0.73 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: 0.86 SLC17A6solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 (220551_at), score: 0.77 SLC1A7solute carrier family 1 (glutamate transporter), member 7 (210923_at), score: 0.73 SLC30A5solute carrier family 30 (zinc transporter), member 5 (220181_x_at), score: 0.69 SLC6A14solute carrier family 6 (amino acid transporter), member 14 (219795_at), score: 0.67 SPAM1sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) (216989_at), score: 0.65 SPARCL1SPARC-like 1 (hevin) (200795_at), score: 0.67 SPG21spastic paraplegia 21 (autosomal recessive, Mast syndrome) (215383_x_at), score: 0.66 SPINLW1serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin) (206318_at), score: 0.83 SPNsialophorin (206057_x_at), score: 0.74 SPTLC3serine palmitoyltransferase, long chain base subunit 3 (220456_at), score: 0.93 SSX3synovial sarcoma, X breakpoint 3 (211731_x_at), score: 0.65 ST3GAL2ST3 beta-galactoside alpha-2,3-sialyltransferase 2 (217650_x_at), score: 0.71 ST8SIA3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 (208064_s_at), score: 0.7 STXBP5Lsyntaxin binding protein 5-like (215518_at), score: 0.64 SYCP1synaptonemal complex protein 1 (206740_x_at), score: 0.84 TAAR2trace amine associated receptor 2 (221394_at), score: 0.76 TAC1tachykinin, precursor 1 (206552_s_at), score: 0.69 TACR1tachykinin receptor 1 (208048_at), score: 0.65 TAS2R16taste receptor, type 2, member 16 (221444_at), score: 0.81 TAS2R9taste receptor, type 2, member 9 (221461_at), score: 0.66 TBX21T-box 21 (220684_at), score: 0.64 TBX6T-box 6 (207684_at), score: 0.78 TGM4transglutaminase 4 (prostate) (217566_s_at), score: 0.65 TIMM8Atranslocase of inner mitochondrial membrane 8 homolog A (yeast) (210800_at), score: 0.82 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: 0.71 TNFRSF9tumor necrosis factor receptor superfamily, member 9 (207536_s_at), score: 0.65 TNFSF10tumor necrosis factor (ligand) superfamily, member 10 (214329_x_at), score: 0.68 TNPO3transportin 3 (212317_at), score: 0.63 TP53TG3TP53 target 3 (220167_s_at), score: 0.81 TP63tumor protein p63 (209863_s_at), score: 0.79 TPTEtransmembrane phosphatase with tensin homology (220205_at), score: 0.67 TRIM36tripartite motif-containing 36 (219736_at), score: 0.75 TRIM45tripartite motif-containing 45 (219923_at), score: 0.66 TRPV1transient receptor potential cation channel, subfamily V, member 1 (219632_s_at), score: 0.73 TSHBthyroid stimulating hormone, beta (214529_at), score: 0.66 TSPAN15tetraspanin 15 (218693_at), score: 0.68 TUBA3Ctubulin, alpha 3c (210527_x_at), score: 0.64 TXNthioredoxin (216609_at), score: 0.67 UBQLN4ubiquilin 4 (222252_x_at), score: 0.79 UGT2B28UDP glucuronosyltransferase 2 family, polypeptide B28 (211682_x_at), score: 1 USP6ubiquitin specific peptidase 6 (Tre-2 oncogene) (206405_x_at), score: 0.86 UTF1undifferentiated embryonic cell transcription factor 1 (208275_x_at), score: 0.76 VEZTvezatin, adherens junctions transmembrane protein (207263_x_at), score: 0.82 VPRBPVpr (HIV-1) binding protein (204377_s_at), score: 0.8 WNT6wingless-type MMTV integration site family, member 6 (71933_at), score: 0.91 XRCC2X-ray repair complementing defective repair in Chinese hamster cells 2 (207598_x_at), score: 0.71 ZBTB39zinc finger and BTB domain containing 39 (205256_at), score: 0.77 ZC3H7Bzinc finger CCCH-type containing 7B (206169_x_at), score: 0.86 ZNF117zinc finger protein 117 (207605_x_at), score: 0.74 ZNF160zinc finger protein 160 (214715_x_at), score: 0.78 ZNF287zinc finger protein 287 (216710_x_at), score: 0.75 ZNF440zinc finger protein 440 (215892_at), score: 0.81 ZNF492zinc finger protein 492 (215532_x_at), score: 0.78 ZNF493zinc finger protein 493 (211064_at), score: 0.66 ZNF639zinc finger protein 639 (218413_s_at), score: 0.81 ZNF701zinc finger protein 701 (220242_x_at), score: 0.63 ZNF749zinc finger protein 749 (215289_at), score: 0.68 ZNF770zinc finger protein 770 (220608_s_at), score: 0.71 ZNF816Azinc finger protein 816A (217541_x_at), score: 0.86 ZPBPzona pellucida binding protein (207021_at), score: 0.75 ZSCAN12zinc finger and SCAN domain containing 12 (206507_at), score: 0.64

Non-Entrez genes

Unknown, score:

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
E-TABM-263-raw-cel-1515485651.cel	1	6	Cycle	hgu133a2	none	Cycle 1
10358_WBS.CEL	1	8	WBS	hgu133plus2	WBS	WBS 1
E-TABM-263-raw-cel-1515485831.cel	10	6	Cycle	hgu133a2	none	Cycle 1
46A.CEL	1	3	DS-mosaic	hgu133plus2	none	DS-mosaic 1
E-TABM-263-raw-cel-1515486211.cel	29	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515485871.cel	12	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486011.cel	19	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515485691.cel	3	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486071.cel	22	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515485951.cel	16	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486171.cel	27	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486411.cel	39	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515485991.cel	18	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515485711.cel	4	6	Cycle	hgu133a2	none	Cycle 1
6Twin.CEL	6	2	DS-twin	hgu133plus2	none	DS-twin 6
E-GEOD-3860-raw-cel-1561690231.cel	4	5	HGPS	hgu133a	HGPS	AG10750
E-GEOD-3860-raw-cel-1561690432.cel	16	5	HGPS	hgu133a	HGPS	AG10750
E-GEOD-4219-raw-cel-1311956418.cel	13	7	Sph-mono	hgu133plus2	none	Sph-mon 1
4Twin.CEL	4	2	DS-twin	hgu133plus2	none	DS-twin 4
3Twin.CEL	3	2	DS-twin	hgu133plus2	Down	DS-twin 3
E-GEOD-4219-raw-cel-1311956275.cel	8	7	Sph-mono	hgu133plus2	none	Sph-mon 1
ctrl c 08-03.CEL	3	1	DS-CC	hgu133a	none	DS-CC 3
t21d 08-03.CEL	7	1	DS-CC	hgu133a	Down	DS-CC 7
2Twin.CEL	2	2	DS-twin	hgu133plus2	none	DS-twin 2
E-GEOD-3407-raw-cel-1437949557.cel	1	4	Cockayne	hgu133a	CS	eGFP
E-GEOD-4219-raw-cel-1311956138.cel	4	7	Sph-mono	hgu133plus2	none	Sph-mon 1
E-GEOD-4219-raw-cel-1311956398.cel	12	7	Sph-mono	hgu133plus2	none	Sph-mon 1
E-GEOD-4219-raw-cel-1311956634.cel	19	7	Sph-mono	hgu133plus2	none	Sph-mon 1
ctrl a 08-03.CEL	1	1	DS-CC	hgu133a	none	DS-CC 1
t21a 08-03.CEL	4	1	DS-CC	hgu133a	Down	DS-CC 4
E-GEOD-4219-raw-cel-1311956083.cel	2	7	Sph-mono	hgu133plus2	none	Sph-mon 1