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skeletal system development

The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).

ossification

The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.

angiogenesis

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

blood vessel development

The process whose specific outcome is the progression of the blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.

osteoblast differentiation

The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, the mesodermal cell that gives rise to bone.

cell activation

A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.

vasculature development

The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure.

immune effector process

Any process of the immune system that occurs as part of an immune response.

activation of immune response

Any process that initiates an immune response.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

antigen processing and presentation of peptide antigen via MHC class I

The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.

acute inflammatory response

Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.

activation of plasma proteins during acute inflammatory response

Any process activating plasma proteins via proteolysis during an acute inflammatory response.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

regionalization

The pattern specification process by which an axis or axes is subdivided in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

proteolysis

The hydrolysis of a peptide bond or bonds within a protein.

cell motion

Any process involved in the controlled movement of a cell.

chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

humoral immune response

An immune response mediated through a body fluid.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell surface receptor linked signal transduction

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

enzyme linked receptor protein signaling pathway

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase.

intracellular signaling cascade

A series of reactions within the cell that occur as a result of a single trigger reaction or compound.

protein kinase cascade

A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

pattern specification process

Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

hemostasis

The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.

behavior

The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

locomotory behavior

The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

response to external stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

anterior/posterior pattern formation

The regionalization process by which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

regulation of signal transduction

Any process that modulates the frequency, rate or extent of signal transduction.

positive regulation of signal transduction

Any process that activates or increases the frequency, rate or extent of signal transduction.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of protein kinase cascade

Any process that modulates the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

positive regulation of cell communication

Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

positive regulation of protein kinase cascade

Any process that increases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

cell migration

The orderly movement of cells from one site to another, often during the development of a multicellular organism or multicellular structure.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

antigen processing and presentation

The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.

leukocyte chemotaxis

The movement of a leukocyte in response to an external stimulus.

regulation of response to external stimulus

Any process that modulates the frequency, rate or extent of a response to an external stimulus.

positive regulation of response to external stimulus

Any process that activates, maintains or increases the rate of a response to an external stimulus.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

locomotion

Self-propelled movement of a cell or organism from one location to another.

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

cellular protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.

leukocyte activation

A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.

lymphocyte activation

A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.

antigen processing and presentation of peptide antigen

The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

blood vessel morphogenesis

The process by which the anatomical structures of blood vessels are generated and organized. Morphogenesis pertains to the creation of form. The blood vessel is the vasculature carrying blood.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

anatomical structure formation

The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

coagulation

The process by which a fluid solution, or part of it, changes into a solid or semisolid mass.

regulation of body fluid levels

Any process that modulates the levels of body fluids.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

leukocyte migration

The movement of leukocytes within or between different tissues and organs of the body.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

localization of cell

Any process by which a cell is transported to, and/or maintained in, a specific location.

cell chemotaxis

The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

bone development

The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

all

This term is the most general term possible

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

immune effector process

Any process of the immune system that occurs as part of an immune response.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

leukocyte activation

A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

positive regulation of cell communication

Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

pattern specification process

Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

anatomical structure formation

The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

regulation of response to external stimulus

Any process that modulates the frequency, rate or extent of a response to an external stimulus.

positive regulation of response to external stimulus

Any process that activates, maintains or increases the rate of a response to an external stimulus.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

cell motion

Any process involved in the controlled movement of a cell.

regulation of body fluid levels

Any process that modulates the levels of body fluids.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

activation of immune response

Any process that initiates an immune response.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

regulation of signal transduction

Any process that modulates the frequency, rate or extent of signal transduction.

positive regulation of cell communication

Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

positive regulation of signal transduction

Any process that activates or increases the frequency, rate or extent of signal transduction.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

osteoblast differentiation

The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, the mesodermal cell that gives rise to bone.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

ossification

The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.

cell chemotaxis

The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

leukocyte migration

The movement of leukocytes within or between different tissues and organs of the body.

leukocyte chemotaxis

The movement of a leukocyte in response to an external stimulus.

positive regulation of response to external stimulus

Any process that activates, maintains or increases the rate of a response to an external stimulus.

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

cellular protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.

positive regulation of signal transduction

Any process that activates or increases the frequency, rate or extent of signal transduction.

bone development

The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.

angiogenesis

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

regulation of protein kinase cascade

Any process that modulates the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

positive regulation of protein kinase cascade

Any process that increases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

positive regulation of protein kinase cascade

Any process that increases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

blood vessel morphogenesis

The process by which the anatomical structures of blood vessels are generated and organized. Morphogenesis pertains to the creation of form. The blood vessel is the vasculature carrying blood.

activation of plasma proteins during acute inflammatory response

Any process activating plasma proteins via proteolysis during an acute inflammatory response.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

lytic vacuole

A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

MHC class I protein complex

A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.

lysosome

A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

MHC protein complex

A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

MHC protein complex

A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

protein binding

Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

calcium ion binding

Interacting selectively with calcium ions (Ca2+).

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

serine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

receptor binding

Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

growth factor binding

Interacting selectively with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.

cytokine activity

Functions to control the survival, growth, differentiation and effector function of tissues and cells.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

metal ion binding

Interacting selectively with any metal ion.

growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.

peptidase activity, acting on L-amino acid peptides

Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

serine hydrolase activity

Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

MHC class I receptor activity

Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.

ion binding

Interacting selectively with ions, charged atoms or groups of atoms.

cation binding

Interacting selectively with cations, charged atoms or groups of atoms with a net positive charge.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

calcium ion binding

Interacting selectively with calcium ions (Ca2+).

serine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

Id	Pvalue	ExpCount	Count	Size	Term
GO:0002376	5.354e-10	22.01	59 C1R, C1S, CBFB, CBLB, CCL2, CCRL1, CD46, CD55, CFH, CFHR1, CSF1, DNASE2, DPP4, EDN1, ERAP1, FAS, FKBP1A, GEM, GPR183, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HMOX1, HOXB7, ICAM1, IL11, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, ITGA1, ITGA4, JARID2, LIF, LY96, MAPK1, NFIL3, NFKB1, NP, OSTM1, PDCD1LG2, PSMB8, PSMB9, RUNX1, SCG2, SHB, SKAP2, SOX4, TGFBR1, TNFSF4, TPD52, TRIM22, VEGFA, ZEB1	475	immune system process
GO:0009611	7.956e-09	10.7	37 ACVR1, C1R, C1S, CCL2, CD46, CD55, CFH, CFHR1, EDN1, F10, F3, FGF7, GAP43, GNA13, HBEGF, HMOX1, IL1RAP, IL23A, IL6, IL6ST, IL8, JMJD3, LMAN1, LY96, NFKB1, NINJ1, OSMR, PARP4, PDGFA, PLAUR, PPARD, PROS1, SCG2, SRF, TFPI, TGM2, TPST1	231	response to wounding
GO:0009605	5.082e-08	17.14	47 ACVR1, ADIPOR2, BHLHE40, C1R, C1S, CCL2, CCRL1, CD46, CD55, CFH, CFHR1, EDN1, F10, F3, FGF2, FGF7, GAP43, GNA13, HBEGF, HMOX1, IL1RAP, IL23A, IL6, IL6ST, IL8, ITGA1, JMJD3, LMAN1, LY96, MAPK1, NFKB1, NINJ1, NPC1, NR4A3, OSMR, PARP4, PDGFA, PLAUR, PPARD, PROS1, SCG2, SLC10A3, SRF, TFPI, TGM2, TPST1, VEGFA	370	response to external stimulus
GO:0032501	1.587e-06	76.35	122 ACVR1, ADRA2A, ANGPTL4, ANO1, ASPH, BBS1, BHLHE40, BMPR2, CBFB, CCL2, CHST11, COL13A1, COL15A1, CORIN, CREG1, CSF1, CST3, DCN, DES, DGKD, DKK2, DNASE2, EDN1, EGR3, EPHA2, ERAP1, F10, F3, FAS, FGF1, FGF2, FGF5, FGF7, FKBP1A, FOSB, FURIN, GAP43, GDF11, GNA13, GPNMB, GRIK2, GSTM3, HBEGF, HEXA, HHEX, HK2, HLX, HMOX1, HOXB5, HOXB6, HOXB7, HSPB7, HTR2A, HTR2B, IDUA, IL11, IL23A, IL6, IL6ST, IL8, ITGA4, ITPR3, JARID2, JUND, KCNN4, LBH, LIF, LMAN1, LRP1, MAN2B1, MAP1S, MAPK1, MEIS1, MEOX1, NFKB1, NINJ1, NOVA1, NP, NR3C1, NR4A3, NRXN3, OSTM1, P2RX4, PBX3, PDGFA, PDLIM3, PLAUR, PPARD, PROS1, RPS4Y1, RTN1, RUNX1, SCG2, SEMA5A, SFRP1, SGCE, SHB, SLC19A2, SLC1A1, SMURF1, SOX4, SPATA20, SPRED2, SPRY2, SPRY4, SRF, STBD1, TBX3, TCTN1, TFPI, TGFBR1, TGM2, TNFAIP2, TNFRSF11B, TNS3, TPD52, TPP1, UTP3, VDR, VEGFA, WWTR1, ZMYM6	1648	multicellular organismal process
GO:0006955	1.856e-06	13.67	38 C1R, C1S, CBLB, CCL2, CCRL1, CD46, CD55, CFH, CFHR1, ERAP1, FAS, FKBP1A, GEM, GPR183, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HMOX1, ICAM1, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, LIF, LY96, MAPK1, NFIL3, PDCD1LG2, PSMB8, PSMB9, TNFSF4, TRIM22, ZEB1	295	immune response
GO:0009887	7.851e-06	14.45	38 ACVR1, ANGPTL4, BBS1, CCL2, CHST11, COL15A1, CST3, DCN, EDN1, ERAP1, FGF1, FGF2, FKBP1A, GDF11, GNA13, HHEX, HMOX1, HOXB5, HOXB6, HOXB7, IDUA, IL6, IL8, JARID2, MAPK1, NR4A3, SCG2, SEMA5A, SHB, SPRY2, SRF, TBX3, TGFBR1, TGM2, TNFAIP2, TNFRSF11B, VDR, VEGFA	312	organ morphogenesis
GO:0032502	8.248e-06	88.16	133 ACVR1, ADIPOR2, ANGPTL4, ANO1, BBS1, BMPR2, CAP2, CASP1, CASP4, CBFB, CCL2, CDC42SE1, CHST11, COL13A1, COL15A1, CORIN, CREG1, CSF1, CST3, DCN, DGKD, DKK2, DNASE2, DOCK1, EDN1, EGR3, EPHA2, ERAP1, ESM1, FAS, FGF1, FGF2, FGF5, FGF7, FKBP1A, FOSB, FURIN, GAP43, GDF11, GNA13, GNPTAB, GPNMB, GRIK2, GSTM3, HBEGF, HEXA, HHEX, HIP1, HIPK3, HLX, HMOX1, HOXB5, HOXB6, HOXB7, HTR2A, HTR2B, HTRA1, IDUA, IGFBP5, IGFBP7, IL11, IL6, IL6ST, IL8, ITGA4, JARID2, JUND, LBH, LIF, LIMS1, LITAF, LRP1, LTBR, MAP1S, MAPK1, MEIS1, MEOX1, MTSS1, NFKB1, NINJ1, NLRP1, NP, NR3C1, NR4A3, NRXN3, OSTM1, P2RX4, PARP4, PBX3, PDGFA, PDLIM3, PPARD, RPS4Y1, RTN1, RUNX1, SCG2, SCML2, SEMA5A, SERPINB2, SETX, SFRP1, SGCE, SGPP1, SHB, SMURF1, SOCS2, SOX4, SPATA20, SPRED2, SPRY2, SPRY4, SRF, STAT1, SULF1, TBX3, TCTN1, TGFBR1, TGM2, TM2D1, TNFAIP2, TNFRSF11B, TNS3, TP53BP2, TPD52, TPP1, TRAF3, TRIM32, UTP3, VDR, VEGFA, VEGFB, WWTR1, ZMYM6	1903	developmental process
GO:0048513	2.188e-05	34.42	66 ACVR1, ANGPTL4, BBS1, BMPR2, CBFB, CCL2, CHST11, COL15A1, CSF1, CST3, DCN, DNASE2, EDN1, EGR3, ERAP1, FAS, FGF1, FGF2, FGF7, FKBP1A, GAP43, GDF11, GNA13, GPNMB, HBEGF, HHEX, HMOX1, HOXB5, HOXB6, HOXB7, HTR2B, IDUA, IL11, IL6, IL8, ITGA4, JARID2, LIF, MAP1S, MAPK1, NFKB1, NINJ1, NP, NR3C1, NR4A3, OSTM1, PDLIM3, PPARD, RUNX1, SCG2, SEMA5A, SGCE, SHB, SMURF1, SOX4, SPRY2, SRF, TBX3, TGFBR1, TGM2, TNFAIP2, TNFRSF11B, TNS3, TPD52, VDR, VEGFA	743	organ development
GO:0008284	3.067e-05	8.756	27 ADRA2A, CCL2, CSF1, EDN1, FGF1, FGF2, FGF7, HBEGF, HTR2A, IL11, IL6, IL6ST, LIF, NAMPT, NP, OSMR, PDCD1LG2, PDGFA, SCG2, SOX4, TBX3, TGFBR1, TGM2, TNFSF4, TNS3, VEGFA, VEGFB	189	positive regulation of cell proliferation
GO:0048583	3.724e-05	5.698	21 C1R, C1S, CD46, CD55, CFH, CFHR1, EDN1, ERAP1, FKBP1A, HMOX1, ICAM1, IL6, IL6ST, IL8, MAPK1, NPC1, OSMR, PDGFA, SCG2, TGM2, VEGFA	123	regulation of response to stimulus
GO:0007275	3.765e-05	59.48	97 ACVR1, ANGPTL4, ANO1, BBS1, BMPR2, CBFB, CCL2, CHST11, COL13A1, COL15A1, CREG1, CSF1, CST3, DCN, DGKD, DKK2, DNASE2, EDN1, EGR3, EPHA2, ERAP1, FAS, FGF1, FGF2, FGF5, FGF7, FKBP1A, FOSB, GAP43, GDF11, GNA13, GPNMB, GSTM3, HBEGF, HEXA, HHEX, HLX, HMOX1, HOXB5, HOXB6, HOXB7, HTR2B, IDUA, IL11, IL6, IL6ST, IL8, ITGA4, JARID2, JUND, LBH, LIF, LRP1, MAP1S, MAPK1, MEIS1, MEOX1, NFKB1, NINJ1, NP, NR3C1, NR4A3, NRXN3, OSTM1, PBX3, PDGFA, PDLIM3, PPARD, RPS4Y1, RTN1, RUNX1, SCG2, SEMA5A, SFRP1, SGCE, SHB, SMURF1, SOX4, SPATA20, SPRED2, SPRY2, SPRY4, SRF, TBX3, TCTN1, TGFBR1, TGM2, TNFAIP2, TNFRSF11B, TNS3, TPD52, TPP1, UTP3, VDR, VEGFA, WWTR1, ZMYM6	1284	multicellular organismal development
GO:0048514	4.246e-05	5.745	21 ACVR1, ANGPTL4, COL15A1, CST3, EDN1, ERAP1, FGF1, FGF2, GNA13, HHEX, HMOX1, IL6, IL8, SCG2, SEMA5A, SHB, SRF, TGFBR1, TGM2, TNFAIP2, VEGFA	124	blood vessel morphogenesis
GO:0048869	4.466e-05	38.17	70 ACVR1, ADIPOR2, ANGPTL4, BBS1, BMPR2, CAP2, CBFB, CDC42SE1, CHST11, COL13A1, COL15A1, CSF1, DGKD, DNASE2, EDN1, EPHA2, ERAP1, ESM1, FAS, FGF1, FGF2, FGF5, GAP43, GDF11, GNA13, GNPTAB, GPNMB, GSTM3, HHEX, HIP1, HLX, HOXB5, HOXB7, HTRA1, IDUA, IGFBP5, IGFBP7, IL11, IL6, IL6ST, ITGA4, JUND, LIF, MAP1S, MAPK1, MTSS1, NFKB1, NP, NRXN3, OSTM1, PPARD, RTN1, RUNX1, SEMA5A, SFRP1, SHB, SMURF1, SOCS2, SOX4, SPATA20, SPRY2, SRF, TBX3, TGFBR1, TNFAIP2, TPD52, TRIM32, VEGFA, VEGFB, WWTR1	824	cellular developmental process
GO:0042127	5.791e-05	17.65	41 ADRA2A, BMPR2, CCL2, CHST11, CSF1, EDN1, FGF1, FGF2, FGF7, GDF11, GPNMB, HBEGF, HHEX, HMOX1, HTR2A, IGFBP5, IGFBP7, IL11, IL6, IL6ST, IL8, JARID2, LIF, NAMPT, NP, OSMR, PDCD1LG2, PDGFA, PPAP2A, SCG2, SKAP2, SOX4, TBX3, TGFBR1, TGM2, TNFSF4, TNS3, TP53I11, TRIB1, VEGFA, VEGFB	381	regulation of cell proliferation
GO:0048518	7.044e-05	40.21	72 ABLIM3, ACVR1, ADRA2A, ANGPTL4, BMPR2, C1R, C1S, CASP1, CASP4, CBFB, CCL2, CD46, CD55, CFH, CFHR1, CSF1, ECM1, EDN1, ERAP1, FAS, FGF1, FGF2, FGF7, FKBP1A, FURIN, GRIK2, HBEGF, HHEX, HIP1, HMOX1, HTR2A, HTR2B, ICAM1, IL11, IL6, IL6ST, IL8, JUND, KCNN4, LIF, LITAF, LTBR, MAP3K7IP2, MAPK1, MEOX1, NAMPT, NFKB1, NLRP1, NP, NR4A3, OSMR, P2RX4, PDCD1LG2, PDGFA, PPARD, RUNX1, SCG2, SMURF1, SOX4, SRF, TBX3, TGFBR1, TGM2, TM2D1, TNFSF4, TNS3, TP53BP2, TRAF3, TRAF3IP2, VEGFA, VEGFB, WWTR1	868	positive regulation of biological process
GO:0001775	8.524e-05	7.042	23 CBFB, CSF1, DPP4, EDN1, FAS, FKBP1A, GNA13, HMOX1, ICAM1, IL11, IL23A, IL6, IL6ST, IL8, ITGA4, NP, P2RX4, PDCD1LG2, PDGFA, SHB, SKAP2, SOX4, TPD52	152	cell activation
GO:0042060	1.115e-04	3.706	16 EDN1, F10, F3, GAP43, GNA13, HBEGF, HMOX1, IL6, LMAN1, NINJ1, PDGFA, PLAUR, PPARD, PROS1, SRF, TFPI	80	wound healing
GO:0050896	1.861e-04	62.54	98 ACVR1, ADIPOR2, ADRA2A, ANGPTL4, BBS1, BHLHE40, C1R, C1S, CBLB, CCL2, CCRL1, CD46, CD55, CFH, CFHR1, CST3, DGKD, DPP4, EDN1, ERAP1, F10, F3, FAS, FGF2, FGF7, FKBP1A, FOSB, GAP43, GEM, GNA13, GPR183, GPX3, GRIK2, GSTM3, H2BFS, HBEGF, HEXA, HIST1H2BK, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HMOX1, HSPB7, HTR2A, ICAM1, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, ITGA1, JMJD3, KCNN4, LGALS3BP, LIF, LMAN1, LY96, MAN2B1, MAP3K2, MAP3K4, MAPK1, NFIL3, NFKB1, NINJ1, NOVA1, NPC1, NR3C1, NR4A3, OSMR, P2RX4, PARP4, PDCD1LG2, PDGFA, PLAUR, PPARD, PROS1, PSMB8, PSMB9, SCG2, SETX, SLC10A3, SOCS2, SRF, STAT1, TFPI, TGM2, TNFSF4, TP53I11, TPST1, TRIB1, TRIM22, UBXN4, VEGFA, ZEB1	1350	response to stimulus
GO:0001525	1.962e-04	4.818	18 ACVR1, ANGPTL4, COL15A1, EDN1, ERAP1, FGF1, FGF2, GNA13, HHEX, HMOX1, IL6, IL8, SCG2, SEMA5A, SHB, SRF, TNFAIP2, VEGFA	104	angiogenesis
GO:0001568	2.000e-04	6.347	21 ACVR1, ANGPTL4, COL15A1, CST3, EDN1, ERAP1, FGF1, FGF2, GNA13, HHEX, HMOX1, IL6, IL8, SCG2, SEMA5A, SHB, SRF, TGFBR1, TGM2, TNFAIP2, VEGFA	137	blood vessel development
GO:0007243	2.288e-04	13.43	33 ADRA2A, CASP1, CCL2, ECM1, EDN1, FGF2, FKBP1A, GNA13, HMOX1, HTR2B, IL11, IL1RL1, IL6, IL6ST, LIF, LITAF, LTBR, LY96, MAP3K2, MAP3K4, MAP3K7IP2, MAPK1, MAPKAPK2, PPARD, RAPGEF2, SCG2, SOCS2, STAT1, STK38L, TGFBR1, TGM2, TRAF3IP2, TRIB1	290	protein kinase cascade
GO:0006952	2.293e-04	12.18	31 ACVR1, C1R, C1S, CCL2, CD46, CD55, CFH, CFHR1, CST3, ERAP1, H2BFS, HIST1H2BK, HLA-B, HLA-G, HMOX1, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, JMJD3, KCNN4, LGALS3BP, LY96, NFKB1, OSMR, PARP4, SCG2, TGM2, TPST1	263	defense response
GO:0001944	2.482e-04	6.439	21 ACVR1, ANGPTL4, COL15A1, CST3, EDN1, ERAP1, FGF1, FGF2, GNA13, HHEX, HMOX1, IL6, IL8, SCG2, SEMA5A, SHB, SRF, TGFBR1, TGM2, TNFAIP2, VEGFA	139	vasculature development
GO:0006954	3.165e-04	7.088	22 ACVR1, C1R, C1S, CCL2, CD46, CD55, CFH, CFHR1, HMOX1, IL1RAP, IL23A, IL6, IL6ST, IL8, JMJD3, LY96, NFKB1, OSMR, PARP4, SCG2, TGM2, TPST1	153	inflammatory response
GO:0030154	3.259e-04	31.22	58 ACVR1, ANGPTL4, BBS1, BMPR2, CBFB, CHST11, COL13A1, COL15A1, CSF1, DNASE2, EDN1, EPHA2, ERAP1, FAS, FGF1, FGF2, FGF5, GAP43, GDF11, GNA13, GNPTAB, GPNMB, GSTM3, HHEX, HIP1, HLX, HOXB5, HOXB7, IL11, IL6, IL6ST, ITGA4, JUND, LIF, MAP1S, MAPK1, NFKB1, NP, NRXN3, OSTM1, PPARD, RTN1, RUNX1, SEMA5A, SFRP1, SHB, SMURF1, SOX4, SPATA20, SPRY2, SRF, TBX3, TGFBR1, TNFAIP2, TPD52, TRIM32, VEGFA, WWTR1	674	cell differentiation
GO:0008283	3.709e-04	26.17	51 ADRA2A, BMPR2, CCL2, CDV3, CHST11, CREG1, CSF1, EDN1, FGF1, FGF2, FGF5, FGF7, FURIN, GDF11, GPNMB, HBEGF, HHEX, HMOX1, HTR2A, IGFBP5, IGFBP7, IL11, IL23A, IL6, IL6ST, IL8, JARID2, LIF, LRP1, NAMPT, NP, OSMR, PDCD1LG2, PDGFA, PDGFD, PPAP2A, PPARD, SCG2, SHB, SKAP2, SOX4, TBX3, TGFBR1, TGM2, TNFSF4, TNS3, TP53I11, TRIB1, VEGFA, VEGFB, ZEB1	565	cell proliferation
GO:0048584	4.078e-04	3.197	14 C1R, C1S, CD46, CD55, CFH, CFHR1, IL6, IL6ST, IL8, MAPK1, OSMR, SCG2, TGM2, VEGFA	69	positive regulation of response to stimulus
GO:0048856	4.414e-04	57.12	90 ACVR1, ADIPOR2, ANGPTL4, BBS1, BMPR2, CAP2, CBFB, CCL2, CDC42SE1, CHST11, COL15A1, CORIN, CSF1, CST3, DCN, DGKD, DNASE2, EDN1, EGR3, EPHA2, ERAP1, ESM1, FAS, FGF1, FGF2, FGF5, FGF7, FKBP1A, GAP43, GDF11, GNA13, GPNMB, GSTM3, HBEGF, HEXA, HHEX, HMOX1, HOXB5, HOXB6, HOXB7, HTR2B, HTRA1, IDUA, IGFBP5, IGFBP7, IL11, IL6, IL6ST, IL8, ITGA4, JARID2, JUND, LIF, MAP1S, MAPK1, MTSS1, NFKB1, NINJ1, NP, NR3C1, NR4A3, NRXN3, OSTM1, PDLIM3, PPARD, RTN1, RUNX1, SCG2, SCML2, SEMA5A, SFRP1, SGCE, SHB, SMURF1, SOCS2, SOX4, SPRY2, SRF, TBX3, TGFBR1, TGM2, TNFAIP2, TNFRSF11B, TNS3, TPD52, TPP1, VDR, VEGFA, VEGFB, WWTR1	1233	anatomical structure development
GO:0048646	5.086e-04	6.764	21 ACVR1, ANGPTL4, BMPR2, COL15A1, EDN1, ERAP1, FGF1, FGF2, FKBP1A, GNA13, HHEX, HMOX1, IL6, IL8, NR4A3, SCG2, SEMA5A, SHB, SRF, TNFAIP2, VEGFA	146	anatomical structure formation
GO:0045321	6.721e-04	6.347	20 CBFB, CSF1, DPP4, EDN1, FAS, FKBP1A, HMOX1, ICAM1, IL11, IL23A, IL6, IL6ST, IL8, ITGA4, NP, PDCD1LG2, SHB, SKAP2, SOX4, TPD52	137	leukocyte activation
GO:0002682	6.836e-04	6.903	21 C1R, C1S, CD46, CD55, CFH, CFHR1, CSF1, ERAP1, FAS, FKBP1A, HMOX1, ICAM1, IL6, IL6ST, LIF, MAPK1, NFKB1, NP, PDCD1LG2, RUNX1, VEGFA	149	regulation of immune system process
GO:0002526	7.064e-04	1.714	10 ACVR1, C1R, C1S, CD46, CD55, CFH, CFHR1, IL6, IL6ST, OSMR	37	acute inflammatory response
GO:0009653	7.160e-04	32.1	58 ACVR1, ADIPOR2, ANGPTL4, BBS1, BMPR2, CAP2, CCL2, CDC42SE1, CHST11, COL15A1, CORIN, CST3, DCN, DGKD, EDN1, ERAP1, ESM1, FGF1, FGF2, FKBP1A, GAP43, GDF11, GNA13, HHEX, HMOX1, HOXB5, HOXB6, HOXB7, HTRA1, IDUA, IGFBP5, IGFBP7, IL6, IL8, JARID2, MAP1S, MAPK1, MTSS1, NINJ1, NR4A3, NRXN3, SCG2, SCML2, SEMA5A, SFRP1, SHB, SOCS2, SPRY2, SRF, TBX3, TGFBR1, TGM2, TNFAIP2, TNFRSF11B, TPD52, VDR, VEGFA, VEGFB	693	anatomical structure morphogenesis
GO:0040012	7.554e-04	3.845	15 BBS1, CSF1, EDN1, FGF2, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, PDGFA, SCG2, TRIB1, VEGFA	83	regulation of locomotion
GO:0050900	8.127e-04	1.39	9 CCL2, EDN1, HMOX1, ICAM1, IL6, IL8, ITGA1, SCG2, VEGFA	30	leukocyte migration
GO:0002474	8.476e-04	0.7876	7 ERAP1, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	17	antigen processing and presentation of peptide antigen via MHC class I
GO:0048870	9.301e-04	8.2	23 ACVR1, BBS1, CCL2, CSF1, EDN1, FGF2, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, ITGA1, PDGFA, PPAP2A, PPARD, SCG2, SRF, TGFBR1, TNS3, TRIB1, VEGFA	177	cell motility
GO:0048731	9.856e-04	46.74	76 ACVR1, ANGPTL4, BBS1, BMPR2, CBFB, CCL2, CHST11, COL15A1, CSF1, CST3, DCN, DNASE2, EDN1, EGR3, EPHA2, ERAP1, FAS, FGF1, FGF2, FGF5, FGF7, FKBP1A, GAP43, GDF11, GNA13, GPNMB, GSTM3, HBEGF, HEXA, HHEX, HMOX1, HOXB5, HOXB6, HOXB7, HTR2B, IDUA, IL11, IL6, IL6ST, IL8, ITGA4, JARID2, JUND, LIF, MAP1S, MAPK1, NFKB1, NINJ1, NP, NR3C1, NR4A3, NRXN3, OSTM1, PDLIM3, PPARD, RTN1, RUNX1, SCG2, SEMA5A, SGCE, SHB, SMURF1, SOX4, SPRY2, SRF, TBX3, TGFBR1, TGM2, TNFAIP2, TNFRSF11B, TNS3, TPD52, TPP1, VDR, VEGFA, WWTR1	1009	system development
GO:0010740	1.316e-03	4.54	16 CASP1, ECM1, FKBP1A, HMOX1, HTR2B, IL11, IL6, IL6ST, LIF, LITAF, LTBR, MAP3K7IP2, PPARD, TGFBR1, TGM2, TRAF3IP2	98	positive regulation of protein kinase cascade
GO:0016477	1.605e-03	7.922	22 ACVR1, CCL2, CSF1, EDN1, FGF2, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, ITGA1, PDGFA, PPAP2A, PPARD, SCG2, SRF, TGFBR1, TNS3, TRIB1, VEGFA	171	cell migration
GO:0050793	1.701e-03	32.38	57 ACVR1, ADIPOR2, ANGPTL4, BMPR2, CASP1, CASP4, CCL2, CDC42SE1, CHST11, CSF1, CST3, DGKD, EDN1, ERAP1, ESM1, FAS, FGF2, FURIN, GDF11, GNA13, GRIK2, HHEX, HIP1, HIPK3, HMOX1, HTRA1, IGFBP5, IGFBP7, IL6, IL6ST, JUND, LIF, MAPK1, NFKB1, NLRP1, NP, P2RX4, PPARD, RUNX1, SCG2, SERPINB2, SFRP1, SMURF1, SOCS2, SOX4, SRF, STAT1, TBX3, TGFBR1, TGM2, TM2D1, TNFRSF11B, TP53BP2, TRAF3, VEGFA, VEGFB, WWTR1	699	regulation of developmental process
GO:0007389	1.853e-03	4.679	16 ACVR1, BMPR2, EDN1, FGF1, FGF2, GDF11, GNA13, HOXB5, HOXB6, HOXB7, MEOX1, PBX3, SEMA5A, SFRP1, TBX3, TGFBR1	101	pattern specification process
GO:0001501	1.982e-03	7.459	21 ACVR1, BMPR2, CBFB, CHST11, EDN1, GDF11, GPNMB, HEXA, HOXB5, HOXB6, HOXB7, IDUA, IL6, IL6ST, JUND, SMURF1, TBX3, TGFBR1, TNFRSF11B, VDR, WWTR1	161	skeletal system development
GO:0010647	2.053e-03	6.903	20 CASP1, ECM1, FKBP1A, GRIK2, HMOX1, HTR2B, IL11, IL6, IL6ST, LIF, LITAF, LTBR, MAP3K7IP2, P2RX4, PPARD, SOX4, TGFBR1, TGM2, TRAF3IP2, VEGFA	149	positive regulation of cell communication
GO:0006928	2.166e-03	12.46	29 ACVR1, ADRA2A, BBS1, CCL2, CSF1, EDN1, FGF2, GAP43, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, ITGA1, MTSS1, NRXN3, PDGFA, PLAUR, PPAP2A, PPARD, SCG2, SEMA5A, SRF, TGFBR1, TNS3, TRIB1, VEGFA	269	cell motion
GO:0051674	2.166e-03	12.46	29 ACVR1, ADRA2A, BBS1, CCL2, CSF1, EDN1, FGF2, GAP43, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, ITGA1, MTSS1, NRXN3, PDGFA, PLAUR, PPAP2A, PPARD, SCG2, SEMA5A, SRF, TGFBR1, TNS3, TRIB1, VEGFA	269	localization of cell
GO:0040011	2.227e-03	10.56	26 ACVR1, BBS1, CCL2, CCRL1, CSF1, EDN1, FGF2, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, ITGA1, MAPK1, PDGFA, PLAUR, PPAP2A, PPARD, SCG2, SRF, TGFBR1, TNS3, TRIB1, VEGFA	228	locomotion
GO:0010646	2.574e-03	19.46	39 ACVR1, BHLHE40, CASP1, CHST11, DKK2, ECM1, EDN1, FKBP1A, GRIK2, HHEX, HMOX1, HTR2A, HTR2B, HTRA1, IGFBP5, IL11, IL1RL1, IL6, IL6ST, LIF, LITAF, LTBR, MAP3K7IP2, NPC1, P2RX4, PPARD, RAPGEF2, RGS2, SMURF1, SOCS2, SOX4, SPRED2, SPRY2, SPRY4, TGFBR1, TGM2, TRAF3IP2, TRIB1, VEGFA	420	regulation of cell communication
GO:0009967	2.702e-03	6.486	19 CASP1, ECM1, FKBP1A, HMOX1, HTR2B, IL11, IL6, IL6ST, LIF, LITAF, LTBR, MAP3K7IP2, P2RX4, PPARD, SOX4, TGFBR1, TGM2, TRAF3IP2, VEGFA	140	positive regulation of signal transduction
GO:0007166	2.973e-03	32.34	56 ACVR1, ADRA2A, APLP2, BMPR2, CBLB, CCL2, CCRL1, CHST11, CPZ, DGKD, DKK2, DOCK1, EDN1, EPHA2, FGF1, FGF2, FGF5, FGF7, FKBP1A, GAP43, GEM, GNA13, GNAL, GPR183, GPR37, GRIK2, HBEGF, HHEX, HTR2A, HTR2B, HTRA1, IGFBP5, IL6, IL6ST, IL8, ITGA1, ITGA4, ITPR3, LIF, LTBP2, LY96, MAPK1, MTSS1, NEDD9, OSMR, PDGFA, PPAP2A, RGS2, SFRP1, SMURF1, SOCS2, SOX4, TGFBR1, TGM2, TRIB1, VEGFA	698	cell surface receptor linked signal transduction
GO:0001649	3.232e-03	1.297	8 ACVR1, BMPR2, CBFB, GPNMB, IL6, IL6ST, JUND, WWTR1	28	osteoblast differentiation
GO:0010627	3.247e-03	5.467	17 CASP1, ECM1, FKBP1A, HMOX1, HTR2B, IL11, IL1RL1, IL6, IL6ST, LIF, LITAF, LTBR, MAP3K7IP2, PPARD, TGFBR1, TGM2, TRAF3IP2	118	regulation of protein kinase cascade
GO:0048002	3.395e-03	0.9729	7 ERAP1, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	21	antigen processing and presentation of peptide antigen
GO:0003002	3.441e-03	3.428	13 BMPR2, EDN1, FGF1, FGF2, GDF11, HOXB5, HOXB6, HOXB7, MEOX1, PBX3, SFRP1, TBX3, TGFBR1	74	regionalization
GO:0050776	3.441e-03	3.428	13 C1R, C1S, CD46, CD55, CFH, CFHR1, ERAP1, FKBP1A, HMOX1, ICAM1, IL6, IL6ST, MAPK1	74	regulation of immune response
GO:0048522	3.726e-03	37.39	62 ABLIM3, ACVR1, ADRA2A, BMPR2, CASP1, CASP4, CBFB, CCL2, CSF1, ECM1, EDN1, FAS, FGF1, FGF2, FGF7, FKBP1A, FURIN, GRIK2, HBEGF, HHEX, HIP1, HMOX1, HTR2A, HTR2B, ICAM1, IL11, IL6, IL6ST, JUND, LIF, LITAF, LTBR, MAP3K7IP2, MAPK1, MEOX1, NAMPT, NFKB1, NLRP1, NP, NR4A3, OSMR, P2RX4, PDCD1LG2, PDGFA, PPARD, RUNX1, SCG2, SMURF1, SOX4, SRF, TBX3, TGFBR1, TGM2, TM2D1, TNFSF4, TNS3, TP53BP2, TRAF3, TRAF3IP2, VEGFA, VEGFB, WWTR1	807	positive regulation of cellular process
GO:0051241	4.188e-03	2.131	10 BMPR2, CST3, EDN1, FURIN, HMOX1, HTR2A, IL6, P2RX4, PDGFA, SMURF1	46	negative regulation of multicellular organismal process
GO:0032879	4.905e-03	9.868	24 BBS1, CSF1, DNAJC1, EDN1, FGF2, FKBP1A, GNA13, HBEGF, HIP1, HMOX1, HTR2A, ICAM1, IGFBP5, IL11, IL6, KCNN4, LIF, NFKB1, P2RX4, PDGFA, RAB5C, TGFBR1, TRIB1, VEGFA	213	regulation of localization
GO:0006959	5.111e-03	1.39	8 C1R, C1S, CCL2, CD46, CD55, CFH, CFHR1, IL6	30	humoral immune response
GO:0009966	5.961e-03	17.47	35 ACVR1, CASP1, CHST11, DKK2, ECM1, EDN1, FKBP1A, HHEX, HMOX1, HTR2B, HTRA1, IGFBP5, IL11, IL1RL1, IL6, IL6ST, LIF, LITAF, LTBR, MAP3K7IP2, P2RX4, PPARD, RAPGEF2, RGS2, SMURF1, SOCS2, SOX4, SPRED2, SPRY2, SPRY4, TGFBR1, TGM2, TRAF3IP2, TRIB1, VEGFA	377	regulation of signal transduction
GO:0051270	6.179e-03	4.169	14 BBS1, CSF1, EDN1, FGF2, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, PDGFA, TGFBR1, TRIB1, VEGFA	90	regulation of cell motion
GO:0007167	6.696e-03	10.75	25 ACVR1, BMPR2, CCL2, CHST11, DGKD, EPHA2, FGF1, FGF2, FGF5, FGF7, FKBP1A, HBEGF, HHEX, HTRA1, IGFBP5, IL6ST, LIF, LTBP2, MTSS1, PDGFA, RGS2, SMURF1, SOCS2, TGFBR1, VEGFA	232	enzyme linked receptor protein signaling pathway
GO:0006935	6.709e-03	3.197	12 CCL2, CCRL1, EDN1, FGF2, IL6, IL8, ITGA1, MAPK1, PDGFA, PLAUR, SCG2, VEGFA	69	chemotaxis
GO:0042330	6.709e-03	3.197	12 CCL2, CCRL1, EDN1, FGF2, IL6, IL8, ITGA1, MAPK1, PDGFA, PLAUR, SCG2, VEGFA	69	taxis
GO:0019882	6.897e-03	1.853	9 ERAP1, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, ICAM1, PSMB8	40	antigen processing and presentation
GO:0051239	7.024e-03	14.82	31 ACVR1, ANGPTL4, BHLHE40, BMPR2, CSF1, CST3, DES, EDN1, ERAP1, FAS, FGF2, FURIN, GRIK2, HBEGF, HHEX, HMOX1, HSPB7, HTR2A, IL6, IL6ST, JUND, LIF, NFKB1, NP, P2RX4, PDGFA, RUNX1, SMURF1, SRF, TBX3, TNFRSF11B	320	regulation of multicellular organismal process
GO:0046649	7.229e-03	5.328	16 CBFB, DPP4, FAS, FKBP1A, ICAM1, IL11, IL23A, IL6, IL6ST, ITGA4, NP, PDCD1LG2, SHB, SKAP2, SOX4, TPD52	115	lymphocyte activation
GO:0032103	7.491e-03	1.112	7 IL6, IL6ST, IL8, OSMR, SCG2, TGM2, VEGFA	24	positive regulation of response to external stimulus
GO:0002541	7.536e-03	0.7876	6 C1R, C1S, CD46, CD55, CFH, CFHR1	17	activation of plasma proteins during acute inflammatory response
GO:0006956	7.536e-03	0.7876	6 C1R, C1S, CD46, CD55, CFH, CFHR1	17	complement activation
GO:0030595	7.536e-03	0.7876	6 CCL2, EDN1, IL6, IL8, ITGA1, SCG2	17	leukocyte chemotaxis
GO:0060326	7.536e-03	0.7876	6 CCL2, EDN1, IL6, IL8, ITGA1, SCG2	17	cell chemotaxis
GO:0007596	7.722e-03	2.316	10 EDN1, F10, F3, GNA13, IL6, LMAN1, PDGFA, PLAUR, PROS1, TFPI	50	blood coagulation
GO:0050817	7.722e-03	2.316	10 EDN1, F10, F3, GNA13, IL6, LMAN1, PDGFA, PLAUR, PROS1, TFPI	50	coagulation
GO:0050878	7.861e-03	2.78	11 EDN1, F10, F3, GNA13, IL6, KCNN4, LMAN1, PDGFA, PLAUR, PROS1, TFPI	60	regulation of body fluid levels
GO:0002684	8.535e-03	3.799	13 C1R, C1S, CD46, CD55, CFH, CFHR1, ICAM1, IL6, IL6ST, MAPK1, NP, PDCD1LG2, VEGFA	82	positive regulation of immune system process
GO:0009952	8.885e-03	2.363	10 BMPR2, GDF11, HOXB5, HOXB6, HOXB7, MEOX1, PBX3, SFRP1, TBX3, TGFBR1	51	anterior/posterior pattern formation
GO:0007154	9.526e-03	90.2	121 ACVR1, ADIPOR2, ADRA2A, ANGPTL4, ANK2, APLP2, BHLHE40, BMPR2, CAP2, CASP1, CBLB, CCL2, CCRL1, CDC42SE1, CHST11, CPZ, DGKD, DKK2, DOCK1, ECM1, EDN1, EGR3, EPHA2, FAS, FGF1, FGF2, FGF5, FGF7, FKBP1A, GAP43, GEM, GNA13, GNAL, GPR183, GPR37, GRIK2, GRN, HBEGF, HEXA, HHEX, HIP1, HMOX1, HTR2A, HTR2B, HTRA1, IGFBP5, IL11, IL1RAP, IL1RL1, IL6, IL6ST, IL8, INPP1, ITGA1, ITGA4, ITPR3, KIDINS220, LGALS3BP, LIF, LITAF, LTBP2, LTBR, LY96, LYN, MAP3K2, MAP3K4, MAP3K7IP2, MAPK1, MAPKAPK2, MFAP4, MTSS1, NAMPT, NEDD9, NFATC1, NFKB1, NLRP1, NOVA1, NPC1, NR3C1, OSMR, P2RX4, PDGFA, PI4KB, PIK3CD, PLAUR, PMEPA1, PPAP2A, PPARD, RAB5C, RAPGEF2, RCAN2, RGS2, RRAD, SCG2, SEMA5A, SFRP1, SHB, SKAP2, SLC1A1, SMURF1, SOCS2, SOX4, SPRED2, SPRY2, SPRY4, STARD13, STAT1, STK38L, TBX3, TEX2, TGFBR1, TGM2, TNFRSF11B, TNFSF4, TP53BP2, TRAF3, TRAF3IP2, TRIB1, VDR, VEGFA, VEGFB	1947	cell communication
GO:0032101	1.019e-02	2.409	10 EDN1, IL6, IL6ST, IL8, NPC1, OSMR, PDGFA, SCG2, TGM2, VEGFA	52	regulation of response to external stimulus
GO:0045597	1.146e-02	3.938	13 ACVR1, BMPR2, CSF1, FGF2, IL6, IL6ST, JUND, LIF, NFKB1, NP, PPARD, RUNX1, SRF	85	positive regulation of cell differentiation
GO:0007165	1.153e-02	83.39	113 ACVR1, ADIPOR2, ADRA2A, ANGPTL4, ANK2, APLP2, BMPR2, CAP2, CASP1, CBLB, CCL2, CCRL1, CDC42SE1, CHST11, CPZ, DGKD, DKK2, DOCK1, ECM1, EDN1, EPHA2, FAS, FGF1, FGF2, FGF5, FGF7, FKBP1A, GAP43, GEM, GNA13, GNAL, GPR183, GPR37, GRIK2, GRN, HBEGF, HHEX, HIP1, HMOX1, HTR2A, HTR2B, HTRA1, IGFBP5, IL11, IL1RAP, IL1RL1, IL6, IL6ST, IL8, INPP1, ITGA1, ITGA4, ITPR3, KIDINS220, LGALS3BP, LIF, LITAF, LTBP2, LTBR, LY96, LYN, MAP3K2, MAP3K4, MAP3K7IP2, MAPK1, MAPKAPK2, MFAP4, MTSS1, NAMPT, NEDD9, NFATC1, NFKB1, NLRP1, NR3C1, OSMR, P2RX4, PDGFA, PI4KB, PIK3CD, PLAUR, PMEPA1, PPAP2A, PPARD, RAB5C, RAPGEF2, RCAN2, RGS2, RRAD, SCG2, SFRP1, SHB, SKAP2, SMURF1, SOCS2, SOX4, SPRED2, SPRY2, SPRY4, STARD13, STAT1, STK38L, TEX2, TGFBR1, TGM2, TNFRSF11B, TNFSF4, TP53BP2, TRAF3, TRAF3IP2, TRIB1, VDR, VEGFA, VEGFB	1800	signal transduction
GO:0048519	1.269e-02	42.67	66 ACVR1, ADIPOR2, ANGPTL4, ARID5A, BCL7A, BHLHE40, BMPR2, CCL2, CHST11, CST3, DKK2, DNAJC1, EDN1, FAS, FGF2, FOSB, FURIN, GDF11, GPNMB, HHEX, HIPK3, HMOX1, HTR2A, HTRA1, IGFBP5, IGFBP7, IL11, IL1RL1, IL6, IL6ST, IL8, JARID2, JMJD3, KANK1, LIF, LMCD1, MAF, MAPK1, MTSS1, NAB1, NFKB1, NPC1, P2RX4, PDCD1LG2, PDGFA, PPAP2A, RGS2, SCG2, SERPINB2, SFRP1, SKAP2, SMURF1, SOCS2, SOX4, STARD13, TBX3, TGFBR1, TNFRSF11B, TP53BP2, TP53I11, TRIB1, VDR, VEGFA, WT1, WWTR1, ZEB1	921	negative regulation of biological process
GO:0051272	1.277e-02	2.038	9 CSF1, EDN1, FGF2, HBEGF, ICAM1, IL6, PDGFA, TGFBR1, VEGFA	44	positive regulation of cell motion
GO:0030334	1.289e-02	3.475	12 CSF1, EDN1, FGF2, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, PDGFA, TRIB1, VEGFA	75	regulation of cell migration
GO:0007599	1.314e-02	2.502	10 EDN1, F10, F3, GNA13, IL6, LMAN1, PDGFA, PLAUR, PROS1, TFPI	54	hemostasis
GO:0048771	1.314e-02	2.502	10 ACVR1, BMPR2, CST3, IL23A, IL6, IL6ST, JUND, SMURF1, TGM2, TPP1	54	tissue remodeling
GO:0048523	1.316e-02	40.26	63 ACVR1, ADIPOR2, ANGPTL4, ARID5A, BCL7A, BHLHE40, CCL2, CHST11, CST3, DKK2, DNAJC1, EDN1, FAS, FGF2, FOSB, FURIN, GDF11, GPNMB, HHEX, HIPK3, HMOX1, HTR2A, HTRA1, IGFBP5, IGFBP7, IL11, IL1RL1, IL6, IL6ST, IL8, JARID2, JMJD3, KANK1, LIF, LMCD1, MAF, MAPK1, MTSS1, NAB1, NFKB1, NPC1, PDCD1LG2, PDGFA, PPAP2A, RGS2, SCG2, SERPINB2, SFRP1, SKAP2, SMURF1, SOCS2, SOX4, STARD13, TBX3, TGFBR1, TP53BP2, TP53I11, TRIB1, VDR, VEGFA, WT1, WWTR1, ZEB1	869	negative regulation of cellular process
GO:0010648	1.379e-02	4.03	13 ACVR1, CHST11, DKK2, HHEX, HTR2A, HTRA1, IGFBP5, IL1RL1, NPC1, RGS2, SMURF1, SOCS2, TRIB1	87	negative regulation of cell communication
GO:0006950	1.560e-02	39.75	62 ACVR1, ADRA2A, ANGPTL4, C1R, C1S, CCL2, CD46, CD55, CFH, CFHR1, CST3, DPP4, EDN1, ERAP1, F10, F3, FGF7, GAP43, GNA13, GPX3, H2BFS, HBEGF, HIST1H2BK, HLA-B, HLA-G, HMOX1, HSPB7, HTR2A, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, JMJD3, KCNN4, LGALS3BP, LMAN1, LY96, MAP3K2, MAP3K4, MAPK1, NFKB1, NINJ1, NPC1, OSMR, P2RX4, PARP4, PDGFA, PLAUR, PPARD, PROS1, SCG2, SETX, SRF, TFPI, TGM2, TP53I11, TPST1, TRIB1, UBXN4, VEGFA	858	response to stress
GO:0007626	1.665e-02	4.679	14 CCL2, CCRL1, EDN1, FGF2, HEXA, IL6, IL8, ITGA1, MAPK1, NOVA1, PDGFA, PLAUR, SCG2, VEGFA	101	locomotory behavior
GO:0007610	1.757e-02	7.69	19 BBS1, CCL2, CCRL1, EDN1, FGF2, FOSB, HEXA, HTR2A, IL6, IL8, ITGA1, MAN2B1, MAPK1, NOVA1, NR4A3, PDGFA, PLAUR, SCG2, VEGFA	166	behavior
GO:0018209	2.090e-02	0.9729	6 GALNT3, HIPK3, IL11, IL6, LIF, TGFBR1	21	peptidyl-serine modification
GO:0048660	2.090e-02	0.9729	6 EDN1, HBEGF, IGFBP5, IL6, TGM2, TRIB1	21	regulation of smooth muscle cell proliferation
GO:0045669	2.142e-02	0.6486	5 ACVR1, BMPR2, IL6, IL6ST, JUND	14	positive regulation of osteoblast differentiation
GO:0044057	2.263e-02	3.752	12 BHLHE40, BMPR2, DES, EDN1, GRIK2, HBEGF, HMOX1, HSPB7, HTR2A, IL6ST, P2RX4, SRF	81	regulation of system process
GO:0030335	2.385e-02	1.807	8 CSF1, EDN1, FGF2, HBEGF, ICAM1, IL6, PDGFA, VEGFA	39	positive regulation of cell migration
GO:0048659	2.566e-02	1.019	6 EDN1, HBEGF, IGFBP5, IL6, TGM2, TRIB1	22	smooth muscle cell proliferation
GO:0007598	2.595e-02	0.1853	3 F10, F3, TFPI	4	blood coagulation, extrinsic pathway
GO:0033135	2.595e-02	0.1853	3 IL11, IL6, LIF	4	regulation of peptidyl-serine phosphorylation
GO:0033138	2.595e-02	0.1853	3 IL11, IL6, LIF	4	positive regulation of peptidyl-serine phosphorylation
GO:0050930	2.595e-02	0.1853	3 IL8, SCG2, VEGFA	4	induction of positive chemotaxis
GO:0065007	2.704e-02	174.6	205 ABLIM3, ACVR1, ADIPOR2, ADRA2A, ANGPTL4, ANK2, APLP2, ARID5A, BBS1, BCL7A, BCORL1, BHLHE40, BMPR2, C1R, C1S, CAP2, CASP1, CASP4, CBFB, CBLB, CCL2, CCRL1, CD46, CD55, CDC42SE1, CFH, CFHR1, CHST11, CORIN, CPZ, CREG1, CSF1, CST3, DES, DGKD, DKK2, DNAJC1, DNASE2, DOCK1, DPP4, ECM1, EDN1, EGR3, EIF3A, EPHA2, ERAP1, ESM1, F10, F3, FAS, FGF1, FGF2, FGF5, FGF7, FKBP1A, FOSB, FURIN, GAP43, GDF11, GEM, GLRX, GNA13, GNAL, GPNMB, GPR183, GPR37, GRIK2, GRN, HBEGF, HEXA, HHEX, HIP1, HIPK3, HLX, HMOX1, HOXB5, HOXB6, HOXB7, HRSP12, HSPB7, HTR2A, HTR2B, HTRA1, ICAM1, IDUA, IGFBP5, IGFBP7, IL11, IL1RAP, IL1RL1, IL6, IL6ST, IL8, INPP1, ITGA1, ITGA4, ITPR3, JARID2, JMJD3, JUND, KANK1, KCNN4, KHDRBS3, KIDINS220, LBH, LGALS3BP, LIF, LITAF, LMAN1, LMCD1, LTBP2, LTBR, LY96, LYN, MAF, MAP3K2, MAP3K4, MAP3K7IP2, MAPK1, MAPKAPK2, MAX, MEIS1, MEIS3P1, MEOX1, MFAP4, MTSS1, NAB1, NAMPT, NEDD9, NFATC1, NFIL3, NFKB1, NLRP1, NP, NPC1, NPC2, NR3C1, NR4A3, OSMR, P2RX4, PBX3, PDCD1LG2, PDGFA, PDGFD, PHTF2, PI4KB, PIK3CD, PLAUR, PMEPA1, PPAP2A, PPARD, PROS1, PSMB8, PSMB9, RAB5C, RAPGEF2, RCAN2, RGS2, RNF141, RRAD, RUNX1, SCG2, SCML2, SERPINB2, SFRP1, SHB, SKAP2, SMURF1, SOCS2, SOX4, SPRED2, SPRY2, SPRY4, SRF, STARD13, STAT1, STK38L, TBL1XR1, TBX3, TEX2, TFPI, TGFBR1, TGM2, TM2D1, TNFRSF11B, TNFSF4, TNS3, TP53BP2, TP53I11, TPP1, TRAF3, TRAF3IP2, TRIB1, TRIM22, VDR, VEGFA, VEGFB, WT1, WWTR1, ZEB1, ZKSCAN3, ZNF143, ZNF282, ZNF35, ZNF672	3768	biological regulation
GO:0065008	2.806e-02	30.25	49 ADIPOR2, BBS1, BMPR2, CCL2, CD55, CDC42SE1, CORIN, DGKD, DNASE2, EDN1, ERAP1, ESM1, F10, F3, FAS, FURIN, GLRX, GNA13, HEXA, HMOX1, HOXB6, HTR2A, HTRA1, IDUA, IGFBP5, IGFBP7, IL11, IL6, ITPR3, KCNN4, LIF, LMAN1, NPC1, NPC2, NR3C1, P2RX4, PDGFA, PLAUR, PROS1, SOCS2, SRF, TBX3, TFPI, TGFBR1, TGM2, TPP1, VDR, VEGFA, VEGFB	653	regulation of biological quality
GO:0043122	2.817e-02	3.336	11 CASP1, ECM1, FKBP1A, HMOX1, HTR2B, IL1RL1, LITAF, LTBR, MAP3K7IP2, TGM2, TRAF3IP2	72	regulation of I-kappaB kinase/NF-kappaB cascade
GO:0006022	2.835e-02	1.436	7 CHST11, GNS, HEXA, IDS, IDUA, ITIH2, SGSH	31	aminoglycan metabolic process
GO:0030203	2.835e-02	1.436	7 CHST11, GNS, HEXA, IDS, IDUA, ITIH2, SGSH	31	glycosaminoglycan metabolic process
GO:0033002	2.835e-02	1.436	7 EDN1, FGF2, HBEGF, IGFBP5, IL6, TGM2, TRIB1	31	muscle cell proliferation
GO:0007249	2.893e-02	4.447	13 CASP1, ECM1, FKBP1A, HMOX1, HTR2B, IL1RL1, LITAF, LTBR, LY96, MAP3K7IP2, STAT1, TGM2, TRAF3IP2	96	I-kappaB kinase/NF-kappaB cascade
GO:0002685	3.028e-02	0.4169	4 HMOX1, ICAM1, IL6, VEGFA	9	regulation of leukocyte migration
GO:0009880	3.094e-02	1.066	6 ACVR1, EDN1, GNA13, MEOX1, SEMA5A, TBX3	23	embryonic pattern specification
GO:0051094	3.431e-02	13.76	27 ACVR1, ANGPTL4, BMPR2, CASP4, CSF1, ERAP1, FAS, FGF2, GRIK2, HIP1, HMOX1, IL6, IL6ST, JUND, LIF, MAPK1, NFKB1, NLRP1, NP, PPARD, RUNX1, SOX4, SRF, TGM2, TM2D1, TP53BP2, TRAF3	297	positive regulation of developmental process
GO:0001569	4.208e-02	0.4633	4 ACVR1, EDN1, GNA13, SEMA5A	10	patterning of blood vessels
GO:0043500	4.208e-02	0.4633	4 EDN1, HMOX1, IL6ST, P2RX4	10	muscle adaptation
GO:0045595	4.269e-02	8.478	19 ACVR1, BMPR2, CSF1, EDN1, FAS, FGF2, GDF11, IL6, IL6ST, JUND, LIF, MAPK1, NFKB1, NP, PPARD, RUNX1, SRF, TBX3, WWTR1	183	regulation of cell differentiation
GO:0045444	4.321e-02	1.158	6 BBS1, ERAP1, IL11, PPARD, TRIM32, WWTR1	25	fat cell differentiation
GO:0018212	4.352e-02	2.038	8 IL11, IL6, IL6ST, LIF, PDGFD, STAT1, TPST1, TPST2	44	peptidyl-tyrosine modification
GO:0022603	4.588e-02	9.914	21 ADIPOR2, ANGPTL4, CDC42SE1, CST3, DGKD, EDN1, ERAP1, ESM1, FGF2, GNA13, HHEX, HMOX1, HTRA1, IGFBP5, IGFBP7, IL6, SOCS2, TGFBR1, TNFRSF11B, VEGFA, VEGFB	214	regulation of anatomical structure morphogenesis
GO:0051093	4.601e-02	13.43	26 ACVR1, ANGPTL4, CCL2, CHST11, CST3, FAS, FURIN, GDF11, HHEX, HIPK3, HMOX1, IL6, IL6ST, MAPK1, NFKB1, SCG2, SERPINB2, SFRP1, SMURF1, SOCS2, SOX4, TBX3, TGFBR1, TNFRSF11B, VEGFA, WWTR1	290	negative regulation of developmental process
GO:0010611	4.735e-02	0.2316	3 EDN1, IL6ST, P2RX4	5	regulation of cardiac muscle hypertrophy
GO:0010612	4.735e-02	0.2316	3 EDN1, IL6ST, P2RX4	5	regulation of cardiac muscle adaptation
GO:0014743	4.735e-02	0.2316	3 EDN1, IL6ST, P2RX4	5	regulation of muscle hypertrophy
GO:0014887	4.735e-02	0.2316	3 EDN1, IL6ST, P2RX4	5	cardiac muscle adaptation
GO:0014888	4.735e-02	0.2316	3 EDN1, IL6ST, P2RX4	5	striated muscle adaptation
GO:0014897	4.735e-02	0.2316	3 EDN1, IL6ST, P2RX4	5	striated muscle hypertrophy
GO:0014898	4.735e-02	0.2316	3 EDN1, IL6ST, P2RX4	5	cardiac muscle hypertrophy
GO:0031330	4.735e-02	0.2316	3 CST3, FURIN, NPC1	5	negative regulation of cellular catabolic process
GO:0043502	4.735e-02	0.2316	3 EDN1, IL6ST, P2RX4	5	regulation of muscle adaptation
GO:0002253	4.805e-02	1.621	7 C1R, C1S, CD46, CD55, CFH, CFHR1, MAPK1	35	activation of immune response
GO:0051260	4.936e-02	1.204	6 DGKD, FAS, GPX3, ITPR3, STOM, TGM2	26	protein homooligomerization

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005576	1.426e-11	31.34	76 A2M, ANGPTL4, C1R, C1S, CCL2, CFH, CFHR1, COL13A1, COL15A1, CPZ, CREG1, CSF1, CST3, DCN, DKK2, DPP4, ECM1, EDN1, ERAP1, F10, FAS, FGF1, FGF2, FGF5, FGF7, FURIN, GDF11, GPX3, GRN, HBEGF, HLA-C, HMOX1, HTRA1, ICAM1, IGFBP5, IGFBP7, IL11, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, ITFG1, ITIH2, LGALS3BP, LIF, LTBP2, LY96, MAN2B2, MFAP4, NID1, NPC2, OLFML2A, PDCD1LG2, PDGFA, PDGFD, PLAUR, PROS1, PSAP, PTGDS, RNASET2, SCG2, SCPEP1, SERPINB2, SFRP1, ST3GAL1, SULF1, SVEP1, TCTN1, TFPI, TNFAIP2, TNFRSF11B, TNFSF4, VEGFA, VEGFB	700	extracellular region
GO:0005615	8.187e-08	11.02	35 A2M, ANGPTL4, CCL2, CFH, CFHR1, CSF1, CST3, DKK2, EDN1, FGF1, FGF2, FGF5, FURIN, GDF11, GPX3, GRN, HBEGF, HMOX1, HTRA1, ICAM1, IGFBP5, IL11, IL23A, IL6, IL8, LGALS3BP, LIF, PDGFA, PSAP, SCG2, SFRP1, SULF1, TNFAIP2, TNFSF4, VEGFA	246	extracellular space
GO:0044421	2.167e-07	17.33	45 A2M, ANGPTL4, CCL2, CFH, CFHR1, COL13A1, COL15A1, CPZ, CSF1, CST3, DCN, DKK2, ECM1, EDN1, FGF1, FGF2, FGF5, FURIN, GDF11, GPX3, GRN, HBEGF, HMOX1, HTRA1, ICAM1, IGFBP5, IL11, IL23A, IL6, IL8, LGALS3BP, LIF, LTBP2, MFAP4, NID1, OLFML2A, PDGFA, PSAP, SCG2, SFRP1, SULF1, TNFAIP2, TNFRSF11B, TNFSF4, VEGFA	387	extracellular region part
GO:0042612	1.158e-03	0.6717	6 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	15	MHC class I protein complex
GO:0000323	1.426e-03	5.015	16 CTSA, CTSZ, DNASE2, GNS, HEXA, IDS, IDUA, LITAF, MAN2B1, MANBA, NPC1, NPC2, PSAP, SCARB2, SGSH, TPP1	112	lytic vacuole
GO:0005764	1.426e-03	5.015	16 CTSA, CTSZ, DNASE2, GNS, HEXA, IDS, IDUA, LITAF, MAN2B1, MANBA, NPC1, NPC2, PSAP, SCARB2, SGSH, TPP1	112	lysosome
GO:0005773	2.378e-03	5.821	17 CTSA, CTSZ, DNASE2, GABARAPL1, GNS, HEXA, IDS, IDUA, LITAF, MAN2B1, MANBA, NPC1, NPC2, PSAP, SCARB2, SGSH, TPP1	130	vacuole
GO:0005887	3.521e-03	24.58	44 ACVR1, ADRA2A, BMPR2, CCRL1, CD46, CD55, CD58, CLEC2B, CORIN, EPHA2, GPNMB, GPR183, GPR37, GRIK2, HBEGF, HLA-A, HLA-B, HLA-C, HTR2A, HTR2B, ICAM1, IL1RAP, IL6, IL6ST, ITGA1, ITGA4, KCNN4, LRP1, NPC1, NRXN3, OSMR, P2RX4, PCDH7, PPAP2A, RAPGEF2, SCARB2, SGCE, SLC1A1, SLC20A2, STBD1, STOM, TGFBR1, TM2D1, TNFSF4	549	integral to plasma membrane
GO:0031226	4.224e-03	24.81	44 ACVR1, ADRA2A, BMPR2, CCRL1, CD46, CD55, CD58, CLEC2B, CORIN, EPHA2, GPNMB, GPR183, GPR37, GRIK2, HBEGF, HLA-A, HLA-B, HLA-C, HTR2A, HTR2B, ICAM1, IL1RAP, IL6, IL6ST, ITGA1, ITGA4, KCNN4, LRP1, NPC1, NRXN3, OSMR, P2RX4, PCDH7, PPAP2A, RAPGEF2, SCARB2, SGCE, SLC1A1, SLC20A2, STBD1, STOM, TGFBR1, TM2D1, TNFSF4	554	intrinsic to plasma membrane
GO:0005886	7.309e-03	64.61	91 ACVR1, ADRA2A, AJAP1, APLP2, BBS1, BMPR2, CADPS2, CAP2, CCRL1, CD46, CD55, CD58, CDC42SE1, CHIC2, CLEC2B, COL13A1, CORIN, CSF1, DDX3Y, DES, DGKD, DPP4, EPHA2, F10, F3, FAS, FURIN, GAP43, GEM, GPNMB, GPR183, GPR37, GRIK2, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6, IL6ST, ITGA1, ITGA4, ITPR3, KCNN4, LIMS1, LRP1, LY96, LYN, MAGI2, NEDD9, NPC1, NRXN3, OSMR, P2RX4, PCDH7, PCDHGA11, PDCD1LG2, PKP2, PLAUR, PMEPA1, PPAP2A, RAB5C, RAPGEF2, SCARB1, SCARB2, SGCE, SHB, SKAP2, SLC19A2, SLC1A1, SLC20A2, SLC38A4, SLC9A3R2, SPRED2, SPRY2, SPRY4, STBD1, STOM, TFPI, TGFBR1, TGM2, TM2D1, TNFSF4, TNS3	1443	plasma membrane
GO:0042611	9.543e-03	0.9851	6 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	22	MHC protein complex
GO:0016020	1.106e-02	141.8	173 ACBD3, ACVR1, ADIPOR2, ADRA2A, AJAP1, ANO1, APLP2, ASPH, ATP13A3, BBS1, BMPR2, BTN3A1, C19orf28, C4orf18, C9orf167, CADPS2, CAP2, CCRL1, CD302, CD46, CD55, CD58, CDC42SE1, CHIC2, CHST11, CLEC2B, COL13A1, CORIN, CPD, CSF1, CSGALNACT2, CYP51A1, DDX3Y, DES, DGKD, DNAJC1, DOCK1, DOCK9, DPP4, DSCR3, EPHA2, ERAP1, F10, F3, FADS3, FAS, FURIN, GABARAPL1, GALNT3, GAP43, GEM, GLT8D2, GNA13, GNPTAB, GPNMB, GPR183, GPR37, GRIK2, HBEGF, HEXA, HIP1, HK2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6, IL6ST, ITFG1, ITGA1, ITGA4, ITPR3, KCNN4, KIAA0247, KIDINS220, KPNA4, LEPROT, LGALS3BP, LHFP, LIMS1, LITAF, LMAN1, LMBRD1, LRIG1, LRP1, LTBR, LY96, LYN, MAGI2, MAN1C1, MAP3K7IP2, MEGF9, NEDD9, NID1, NINJ1, NPC1, NR3C1, NRXN3, OLFML2A, OSMR, OSTM1, P2RX4, PCDH7, PCDHGA11, PDCD1LG2, PDGFA, PDGFD, PI4KB, PKP2, PLAUR, PMEPA1, PPAP2A, PSAP, PTGDS, RAB5C, RANBP2, RAPGEF2, RTN1, SCARB1, SCARB2, SCYL2, SEC23IP, SEMA5A, SGCE, SGPP1, SHB, SKAP2, SLC10A3, SLC19A2, SLC1A1, SLC20A2, SLC2A10, SLC38A4, SLC9A3R2, SLCO3A1, SPRED2, SPRY2, SPRY4, SQLE, SQRDL, ST3GAL1, STARD13, STBD1, STOM, SVEP1, TEX2, TFPI, TGFBR1, TGM2, TM2D1, TM6SF1, TMBIM4, TMEM39A, TMEM41B, TMEM51, TNFSF4, TNS3, TOR1AIP1, TPST1, TPST2, UBXN4, VEGFA, VEGFB, WTAP, YIPF6, YRDC	3167	membrane
GO:0044459	1.262e-02	39.18	60 ACVR1, ADRA2A, AJAP1, BMPR2, CADPS2, CCRL1, CD46, CD55, CD58, CLEC2B, CORIN, DPP4, EPHA2, FAS, GAP43, GPNMB, GPR183, GPR37, GRIK2, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6, IL6ST, ITGA1, ITGA4, ITPR3, KCNN4, LIMS1, LRP1, MAGI2, NEDD9, NPC1, NRXN3, OSMR, P2RX4, PCDH7, PKP2, PPAP2A, RAPGEF2, SCARB2, SGCE, SLC1A1, SLC20A2, SLC9A3R2, STBD1, STOM, TGFBR1, TM2D1, TNFSF4, TNS3	875	plasma membrane part
GO:0009986	1.838e-02	5.821	15 BMPR2, CORIN, DPP4, FAS, FURIN, HBEGF, ICAM1, IL1RL1, IL6ST, ITGA1, ITGA4, PDGFA, PLAUR, SULF1, VEGFA	130	cell surface
GO:0016021	2.121e-02	90.54	117 ACVR1, ADIPOR2, ADRA2A, AJAP1, ANO1, APLP2, ASPH, ATP13A3, BMPR2, BTN3A1, C19orf28, C4orf18, C9orf167, CCRL1, CD302, CD46, CD55, CD58, CHST11, CLEC2B, COL13A1, CORIN, CPD, CSF1, CSGALNACT2, CYP51A1, DNAJC1, DPP4, EPHA2, ERAP1, F3, FADS3, FAS, FURIN, GALNT3, GLT8D2, GNPTAB, GPNMB, GPR183, GPR37, GRIK2, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6, IL6ST, ITFG1, ITGA1, ITGA4, ITPR3, KCNN4, KIAA0247, KIDINS220, KPNA4, LHFP, LMAN1, LMBRD1, LRIG1, LRP1, LTBR, MAN1C1, MEGF9, NINJ1, NPC1, NRXN3, OSMR, OSTM1, P2RX4, PCDH7, PCDHGA11, PDCD1LG2, PKP2, PLAUR, PMEPA1, PPAP2A, PSAP, RANBP2, RAPGEF2, RTN1, SCARB1, SCARB2, SEMA5A, SGCE, SGPP1, SLC19A2, SLC1A1, SLC20A2, SLC2A10, SLC38A4, SLCO3A1, SQLE, ST3GAL1, STBD1, STOM, TEX2, TGFBR1, TM2D1, TM6SF1, TMBIM4, TMEM39A, TMEM41B, TMEM51, TNFSF4, TOR1AIP1, TPST1, TPST2, UBXN4, YIPF6	2022	integral to membrane
GO:0031224	3.334e-02	91.84	117 ACVR1, ADIPOR2, ADRA2A, AJAP1, ANO1, APLP2, ASPH, ATP13A3, BMPR2, BTN3A1, C19orf28, C4orf18, C9orf167, CCRL1, CD302, CD46, CD55, CD58, CHST11, CLEC2B, COL13A1, CORIN, CPD, CSF1, CSGALNACT2, CYP51A1, DNAJC1, DPP4, EPHA2, ERAP1, F3, FADS3, FAS, FURIN, GALNT3, GLT8D2, GNPTAB, GPNMB, GPR183, GPR37, GRIK2, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6, IL6ST, ITFG1, ITGA1, ITGA4, ITPR3, KCNN4, KIAA0247, KIDINS220, KPNA4, LHFP, LMAN1, LMBRD1, LRIG1, LRP1, LTBR, MAN1C1, MEGF9, NINJ1, NPC1, NRXN3, OSMR, OSTM1, P2RX4, PCDH7, PCDHGA11, PDCD1LG2, PKP2, PLAUR, PMEPA1, PPAP2A, PSAP, RANBP2, RAPGEF2, RTN1, SCARB1, SCARB2, SEMA5A, SGCE, SGPP1, SLC19A2, SLC1A1, SLC20A2, SLC2A10, SLC38A4, SLCO3A1, SQLE, ST3GAL1, STBD1, STOM, TEX2, TGFBR1, TM2D1, TM6SF1, TMBIM4, TMEM39A, TMEM41B, TMEM51, TNFSF4, TOR1AIP1, TPST1, TPST2, UBXN4, YIPF6	2051	intrinsic to membrane
GO:0043235	3.634e-02	2.239	8 ACVR1, CSF1, IL6, IL6ST, ITGA1, ITGA4, OSMR, TGFBR1	50	receptor complex
GO:0005900	4.485e-02	0.08956	2 IL6ST, OSMR	2	oncostatin-M receptor complex

Id	Pvalue	ExpCount	Count	Size	Term
GO:0004871	2.855e-06	35.5	72 ACVR1, ADIPOR2, ADRA2A, BMPR2, CBLB, CCL2, CCRL1, CD46, CORIN, ECM1, EPHA2, FAS, FKBP1A, GNA13, GNAL, GPR183, GPR37, GRIK2, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HMOX1, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6ST, ITGA1, ITGA4, ITPR3, LGALS3BP, LITAF, LRP1, LTBR, LY96, LYN, MAP3K2, MAP3K4, MAPK1, MAPKAPK2, MEGF9, NPC1, NR3C1, NR4A3, NRXN3, OSMR, P2RX4, PDCD1LG2, PLAUR, PPARD, RAPGEF2, RGS2, SCARB1, SCARB2, SEMA5A, SH3BGRL, SHB, SKAP2, SLC20A2, SOCS2, STAT1, TGFBR1, TM2D1, TNFRSF11B, TP53BP2, TRAF3, VDR	798	signal transducer activity
GO:0060089	2.855e-06	35.5	72 ACVR1, ADIPOR2, ADRA2A, BMPR2, CBLB, CCL2, CCRL1, CD46, CORIN, ECM1, EPHA2, FAS, FKBP1A, GNA13, GNAL, GPR183, GPR37, GRIK2, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HMOX1, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6ST, ITGA1, ITGA4, ITPR3, LGALS3BP, LITAF, LRP1, LTBR, LY96, LYN, MAP3K2, MAP3K4, MAPK1, MAPKAPK2, MEGF9, NPC1, NR3C1, NR4A3, NRXN3, OSMR, P2RX4, PDCD1LG2, PLAUR, PPARD, RAPGEF2, RGS2, SCARB1, SCARB2, SEMA5A, SH3BGRL, SHB, SKAP2, SLC20A2, SOCS2, STAT1, TGFBR1, TM2D1, TNFRSF11B, TP53BP2, TRAF3, VDR	798	molecular transducer activity
GO:0004872	5.891e-05	23.71	51 ACVR1, ADIPOR2, ADRA2A, BMPR2, CCRL1, CD46, CORIN, EPHA2, FAS, FKBP1A, GPR183, GPR37, GRIK2, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6ST, ITGA1, ITGA4, ITPR3, LGALS3BP, LRP1, LTBR, LY96, MEGF9, NPC1, NR3C1, NR4A3, NRXN3, OSMR, P2RX4, PDCD1LG2, PLAUR, PPARD, SCARB1, SCARB2, SEMA5A, SLC20A2, TGFBR1, TM2D1, TNFRSF11B, VDR	533	receptor activity
GO:0019838	1.777e-04	2.803	14 A2M, ACVR1, ESM1, FURIN, HTRA1, IGFBP5, IGFBP7, IL1RAP, IL1RL1, IL6ST, LTBP2, OSMR, PDGFA, TGFBR1	63	growth factor binding
GO:0032393	2.026e-04	0.4004	6 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	9	MHC class I receptor activity
GO:0008083	8.349e-04	4.182	16 CSF1, ERAP1, FGF1, FGF2, FGF5, FGF7, GDF11, GRN, HBEGF, IL11, IL6, LIF, PDGFA, PDGFD, VEGFA, VEGFB	94	growth factor activity
GO:0005125	2.992e-03	3.248	13 CCL2, CSF1, GRN, IL11, IL23A, IL6, IL8, LIF, NAMPT, SCG2, TNFRSF11B, TNFSF4, VEGFA	73	cytokine activity
GO:0008236	4.495e-03	2.936	12 C1R, C1S, CORIN, CPD, CTSA, DPP4, F10, FURIN, HTRA1, SCPEP1, SERPINB2, TPP1	66	serine-type peptidase activity
GO:0017171	4.495e-03	2.936	12 C1R, C1S, CORIN, CPD, CTSA, DPP4, F10, FURIN, HTRA1, SCPEP1, SERPINB2, TPP1	66	serine hydrolase activity
GO:0005509	6.139e-03	17.89	36 ANO1, ASPH, C1R, C1S, CADPS2, CBLB, EFHD1, F10, FURIN, GALNT3, GNPTAB, GNS, HPCAL1, IDS, ITGA1, ITGA4, ITPR3, LRP1, LTBP2, MACF1, MAN1C1, MFAP4, NID1, NRXN3, PCDH7, PCDHGA11, PROS1, RAPGEF2, SCG2, SGCE, SGSH, STAT1, SULF1, SVEP1, TGM2, TPD52	402	calcium ion binding
GO:0005102	1.438e-02	18.15	35 ANGPTL4, CCL2, CSF1, EDN1, ERAP1, FGF1, FGF2, FGF5, FGF7, FKBP1A, GDF11, GPNMB, GRN, HBEGF, ICAM1, IL11, IL23A, IL6, IL6ST, IL8, LIF, MFAP4, MTSS1, NAMPT, P2RX4, PDGFA, PDGFD, PSMB8, SCG2, SOCS2, TGFBR1, TNFRSF11B, TNFSF4, VEGFA, VEGFB	408	receptor binding
GO:0004888	1.826e-02	14.86	30 ACVR1, ADRA2A, BMPR2, CCRL1, CORIN, EPHA2, FAS, FKBP1A, GPR183, GPR37, GRIK2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6ST, LGALS3BP, NPC1, OSMR, P2RX4, SEMA5A, TGFBR1, TM2D1	334	transmembrane receptor activity
GO:0004185	2.947e-02	0.178	3 CPD, CTSA, SCPEP1	4	serine-type carboxypeptidase activity
GO:0070008	2.947e-02	0.178	3 CPD, CTSA, SCPEP1	4	serine-type exopeptidase activity
GO:0004252	4.551e-02	2.447	9 C1R, C1S, CORIN, DPP4, F10, FURIN, HTRA1, SERPINB2, TPP1	55	serine-type endopeptidase activity
GO:0008484	4.613e-02	0.4449	4 GNS, IDS, SGSH, SULF1	10	sulfuric ester hydrolase activity

Id	Pvalue	ExpCount	Count	Size	Term
04610	1.932e-04	1.883	11 A2M, C1R, C1S, CD46, CD55, CFH, F10, F3, PLAUR, PROS1, TFPI	34	Complement and coagulation cascades
04060	1.026e-03	6.758	20 ACVR1, BMPR2, CCL2, CSF1, FAS, IL11, IL1RAP, IL23A, IL6, IL6ST, IL8, LIF, LTBR, OSMR, PDGFA, TGFBR1, TNFRSF11B, TNFSF4, VEGFA, VEGFB	122	Cytokine-cytokine receptor interaction
05332	1.180e-03	1.163	8 FAS, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, IL6	21	Graft-versus-host disease
01032	2.256e-03	1.274	8 GNS, HEXA, IDS, IDUA, MAN2B1, MAN2B2, MANBA, SGSH	23	Glycan structures - degradation
05330	8.211e-03	1.163	7 FAS, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	21	Allograft rejection
05320	1.095e-02	1.219	7 FAS, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	22	Autoimmune thyroid disease
04940	2.559e-02	1.44	7 FAS, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	26	Type I diabetes mellitus
00531	3.908e-02	0.7755	5 GNS, HEXA, IDS, IDUA, SGSH	14	Glycosaminoglycan degradation
04630	4.844e-02	4.875	13 CBLB, IL11, IL23A, IL6, IL6ST, LIF, OSMR, PIK3CD, SOCS2, SPRED2, SPRY2, SPRY4, STAT1	88	Jak-STAT signaling pathway

No enriched terms

No enriched terms

Entrez genes

A2Malpha-2-macroglobulin (217757_at), score: 0.23 ABHD4abhydrolase domain containing 4 (218581_at), score: 0.2 ABLIM3actin binding LIM protein family, member 3 (205730_s_at), score: 0.25 ACBD3acyl-Coenzyme A binding domain containing 3 (202323_s_at), score: 0.25 ACVR1activin A receptor, type I (203935_at), score: 0.21 ADIPOR2adiponectin receptor 2 (201346_at), score: 0.2 ADRA2Aadrenergic, alpha-2A-, receptor (209869_at), score: 0.45 AJAP1adherens junctions associated protein 1 (206460_at), score: 0.36 AKIRIN1akirin 1 (217893_s_at), score: 0.22 ANGPTL4angiopoietin-like 4 (221009_s_at), score: 0.46 ANK2ankyrin 2, neuronal (202920_at), score: 0.19 ANO1anoctamin 1, calcium activated chloride channel (218804_at), score: 0.29 APLP2amyloid beta (A4) precursor-like protein 2 (208702_x_at), score: 0.24 ARID5AAT rich interactive domain 5A (MRF1-like) (213138_at), score: 0.27 ARMC9armadillo repeat containing 9 (219637_at), score: 0.21 ASPHaspartate beta-hydroxylase (205808_at), score: 0.24 ATP13A3ATPase type 13A3 (219558_at), score: 0.38 BBS1Bardet-Biedl syndrome 1 (218471_s_at), score: 0.19 BCL7AB-cell CLL/lymphoma 7A (203795_s_at), score: 0.28 BCORL1BCL6 co-repressor-like 1 (219444_at), score: -0.76 BHLHE40basic helix-loop-helix family, member e40 (201170_s_at), score: 0.2 BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) (210214_s_at), score: 0.33 BTN3A1butyrophilin, subfamily 3, member A1 (209770_at), score: 0.18 C11orf20chromosome 11 open reading frame 20 (219883_at), score: -0.76 C17orf71chromosome 17 open reading frame 71 (218514_at), score: 0.19 C17orf91chromosome 17 open reading frame 91 (214696_at), score: 0.3 C19orf28chromosome 19 open reading frame 28 (220178_at), score: 0.28 C1Rcomplement component 1, r subcomponent (212067_s_at), score: 0.44 C1Scomplement component 1, s subcomponent (208747_s_at), score: 0.27 C4orf18chromosome 4 open reading frame 18 (219872_at), score: 0.22 C9orf167chromosome 9 open reading frame 167 (219620_x_at), score: 0.3 CADPS2Ca++-dependent secretion activator 2 (219572_at), score: 0.33 CAP2CAP, adenylate cyclase-associated protein, 2 (yeast) (212554_at), score: 0.2 CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (211368_s_at), score: 0.24 CASP4caspase 4, apoptosis-related cysteine peptidase (209310_s_at), score: 0.28 CBFBcore-binding factor, beta subunit (206788_s_at), score: 0.28 CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b (209682_at), score: 0.26 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: 0.37 CCRL1chemokine (C-C motif) receptor-like 1 (220351_at), score: 0.22 CD302CD302 molecule (203799_at), score: 0.36 CD46CD46 molecule, complement regulatory protein (211574_s_at), score: 0.19 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: 0.25 CD58CD58 molecule (211744_s_at), score: 0.21 CDC42SE1CDC42 small effector 1 (218157_x_at), score: 0.3 CDV3CDV3 homolog (mouse) (213548_s_at), score: 0.26 CFHcomplement factor H (213800_at), score: 0.19 CFHR1complement factor H-related 1 (215388_s_at), score: 0.21 CHIC2cysteine-rich hydrophobic domain 2 (219492_at), score: 0.21 CHST11carbohydrate (chondroitin 4) sulfotransferase 11 (219634_at), score: 0.18 CLEC2BC-type lectin domain family 2, member B (209732_at), score: 0.25 CLIP1CAP-GLY domain containing linker protein 1 (210716_s_at), score: 0.21 CLIP3CAP-GLY domain containing linker protein 3 (212358_at), score: 0.2 COL13A1collagen, type XIII, alpha 1 (211343_s_at), score: 0.19 COL15A1collagen, type XV, alpha 1 (203477_at), score: 0.55 CORINcorin, serine peptidase (220356_at), score: 0.24 CPDcarboxypeptidase D (201942_s_at), score: 0.24 CPZcarboxypeptidase Z (211062_s_at), score: 0.43 CREG1cellular repressor of E1A-stimulated genes 1 (201200_at), score: 0.4 CSF1colony stimulating factor 1 (macrophage) (209716_at), score: 0.24 CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 2 (222235_s_at), score: 0.24 CST3cystatin C (201360_at), score: 0.36 CTSAcathepsin A (200661_at), score: 0.27 CTSOcathepsin O (203758_at), score: 0.29 CTSZcathepsin Z (210042_s_at), score: 0.19 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: 0.36 DAAM2dishevelled associated activator of morphogenesis 2 (212793_at), score: 0.22 DAZAP2DAZ associated protein 2 (212595_s_at), score: 0.26 DCNdecorin (211896_s_at), score: 0.36 DDX3YDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked (205000_at), score: 0.36 DENND3DENN/MADD domain containing 3 (212975_at), score: 0.26 DESdesmin (202222_s_at), score: -1 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: 0.38 DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 9 (212105_s_at), score: 0.22 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: 0.29 DNAJC1DnaJ (Hsp40) homolog, subfamily C, member 1 (218409_s_at), score: 0.2 DNASE2deoxyribonuclease II, lysosomal (214992_s_at), score: 0.28 DOCK1dedicator of cytokinesis 1 (203187_at), score: 0.19 DOCK9dedicator of cytokinesis 9 (212538_at), score: 0.32 DPP4dipeptidyl-peptidase 4 (211478_s_at), score: 0.37 DSCR3Down syndrome critical region gene 3 (203635_at), score: 0.18 DUSP14dual specificity phosphatase 14 (203367_at), score: 0.2 DUSP3dual specificity phosphatase 3 (201537_s_at), score: 0.24 ECM1extracellular matrix protein 1 (209365_s_at), score: 0.36 EDN1endothelin 1 (218995_s_at), score: 0.29 EFHD1EF-hand domain family, member D1 (209343_at), score: 0.25 EGR3early growth response 3 (206115_at), score: 0.38 EIF1AYeukaryotic translation initiation factor 1A, Y-linked (204409_s_at), score: 0.27 EIF3Aeukaryotic translation initiation factor 3, subunit A (200596_s_at), score: 0.2 EPHA2EPH receptor A2 (203499_at), score: 0.2 ERAP1endoplasmic reticulum aminopeptidase 1 (214012_at), score: 0.29 ESM1endothelial cell-specific molecule 1 (208394_x_at), score: 0.22 EXD3exonuclease 3'-5' domain containing 3 (220838_at), score: -0.78 F10coagulation factor X (205620_at), score: 0.34 F3coagulation factor III (thromboplastin, tissue factor) (204363_at), score: 0.28 FADS3fatty acid desaturase 3 (216080_s_at), score: 0.29 FASFas (TNF receptor superfamily, member 6) (216252_x_at), score: 0.33 FGF1fibroblast growth factor 1 (acidic) (205117_at), score: 0.27 FGF2fibroblast growth factor 2 (basic) (204421_s_at), score: 0.24 FGF5fibroblast growth factor 5 (210310_s_at), score: 0.28 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: 0.38 FHOD1formin homology 2 domain containing 1 (218530_at), score: 0.37 FKBP1AFK506 binding protein 1A, 12kDa (210186_s_at), score: 0.22 FLJ10404hypothetical protein FLJ10404 (218920_at), score: -0.78 FOSBFBJ murine osteosarcoma viral oncogene homolog B (202768_at), score: 0.42 FURINfurin (paired basic amino acid cleaving enzyme) (201945_at), score: 0.26 GABARAPL1GABA(A) receptor-associated protein like 1 (208868_s_at), score: 0.18 GALNT3UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) (203397_s_at), score: 0.25 GAP43growth associated protein 43 (204471_at), score: -0.88 GDF11growth differentiation factor 11 (216860_s_at), score: -0.76 GEMGTP binding protein overexpressed in skeletal muscle (204472_at), score: 0.38 GLRXglutaredoxin (thioltransferase) (209276_s_at), score: 0.2 GLT8D2glycosyltransferase 8 domain containing 2 (221447_s_at), score: 0.21 GNA13guanine nucleotide binding protein (G protein), alpha 13 (206917_at), score: 0.19 GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (206355_at), score: -0.79 GNPTABN-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (212959_s_at), score: 0.29 GNSglucosamine (N-acetyl)-6-sulfatase (203676_at), score: 0.29 GPD1Lglycerol-3-phosphate dehydrogenase 1-like (212510_at), score: 0.21 GPNMBglycoprotein (transmembrane) nmb (201141_at), score: 0.67 GPR183G protein-coupled receptor 183 (205419_at), score: 0.3 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: 0.32 GPX3glutathione peroxidase 3 (plasma) (214091_s_at), score: 0.33 GRAMD3GRAM domain containing 3 (218706_s_at), score: 0.39 GRIK2glutamate receptor, ionotropic, kainate 2 (213845_at), score: 0.26 GRNgranulin (211284_s_at), score: 0.33 GSTM1glutathione S-transferase mu 1 (204550_x_at), score: 0.23 GSTM3glutathione S-transferase mu 3 (brain) (202554_s_at), score: 0.19 GSTT1glutathione S-transferase theta 1 (203815_at), score: 0.2 H2BFSH2B histone family, member S (208579_x_at), score: 0.27 HBEGFheparin-binding EGF-like growth factor (203821_at), score: 0.44 HEXAhexosaminidase A (alpha polypeptide) (201765_s_at), score: 0.18 HHEXhematopoietically expressed homeobox (215933_s_at), score: 0.33 HIP1huntingtin interacting protein 1 (205425_at), score: 0.24 HIPK3homeodomain interacting protein kinase 3 (210148_at), score: 0.27 HIST1H2AChistone cluster 1, H2ac (215071_s_at), score: 0.3 HIST1H2BKhistone cluster 1, H2bk (209806_at), score: 0.28 HIST1H4Ehistone cluster 1, H4e (206951_at), score: -0.78 HK2hexokinase 2 (202934_at), score: 0.31 HLA-Amajor histocompatibility complex, class I, A (217436_x_at), score: 0.34 HLA-Bmajor histocompatibility complex, class I, B (211911_x_at), score: 0.35 HLA-Cmajor histocompatibility complex, class I, C (211799_x_at), score: 0.52 HLA-Emajor histocompatibility complex, class I, E (200904_at), score: 0.5 HLA-Fmajor histocompatibility complex, class I, F (204806_x_at), score: 0.45 HLA-Gmajor histocompatibility complex, class I, G (211530_x_at), score: 0.19 HLXH2.0-like homeobox (214438_at), score: 0.23 HMOX1heme oxygenase (decycling) 1 (203665_at), score: 0.33 HOXB5homeobox B5 (205601_s_at), score: 0.24 HOXB6homeobox B6 (205366_s_at), score: 0.48 HOXB7homeobox B7 (204779_s_at), score: 0.36 HPCAL1hippocalcin-like 1 (205462_s_at), score: 0.28 HRSP12heat-responsive protein 12 (203790_s_at), score: 0.19 HSPB7heat shock 27kDa protein family, member 7 (cardiovascular) (218934_s_at), score: 0.19 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: 0.27 HTR2B5-hydroxytryptamine (serotonin) receptor 2B (206638_at), score: 0.32 HTRA1HtrA serine peptidase 1 (201185_at), score: 0.22 ICAM1intercellular adhesion molecule 1 (202638_s_at), score: 0.21 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: 0.33 IDSiduronate 2-sulfatase (202439_s_at), score: 0.24 IDUAiduronidase, alpha-L- (205059_s_at), score: 0.23 IGFBP5insulin-like growth factor binding protein 5 (203424_s_at), score: 0.28 IGFBP7insulin-like growth factor binding protein 7 (201162_at), score: 0.34 IL11interleukin 11 (206924_at), score: 0.31 IL1RAPinterleukin 1 receptor accessory protein (205227_at), score: 0.37 IL1RL1interleukin 1 receptor-like 1 (207526_s_at), score: 0.24 IL23Ainterleukin 23, alpha subunit p19 (211796_s_at), score: 0.29 IL6interleukin 6 (interferon, beta 2) (205207_at), score: 0.44 IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor) (204864_s_at), score: 0.32 IL8interleukin 8 (202859_x_at), score: 0.23 INPP1inositol polyphosphate-1-phosphatase (202794_at), score: 0.24 ITFG1integrin alpha FG-GAP repeat containing 1 (221449_s_at), score: 0.24 ITGA1integrin, alpha 1 (214660_at), score: 0.32 ITGA4integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (205885_s_at), score: 0.24 ITIH2inter-alpha (globulin) inhibitor H2 (204987_at), score: -0.76 ITPR3inositol 1,4,5-triphosphate receptor, type 3 (201189_s_at), score: 0.23 JARID1Djumonji, AT rich interactive domain 1D (206700_s_at), score: 0.23 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: 0.22 JMJD3jumonji domain containing 3, histone lysine demethylase (213146_at), score: 0.37 JUNDjun D proto-oncogene (203751_x_at), score: 0.27 KANK1KN motif and ankyrin repeat domains 1 (213005_s_at), score: 0.19 KCNN4potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (204401_at), score: 0.24 KHDRBS3KH domain containing, RNA binding, signal transduction associated 3 (209781_s_at), score: 0.34 KIAA0247KIAA0247 (202181_at), score: 0.25 KIDINS220kinase D-interacting substrate, 220kDa (212162_at), score: 0.19 KLHL21kelch-like 21 (Drosophila) (203068_at), score: 0.34 KLHL26kelch-like 26 (Drosophila) (219354_at), score: 0.25 KPNA4karyopherin alpha 4 (importin alpha 3) (209653_at), score: 0.28 LARP5La ribonucleoprotein domain family, member 5 (208953_at), score: 0.2 LBHlimb bud and heart development homolog (mouse) (221011_s_at), score: 0.26 LEPREL1leprecan-like 1 (218717_s_at), score: 0.18 LEPROTleptin receptor overlapping transcript (202378_s_at), score: 0.28 LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein (200923_at), score: 0.23 LHFPlipoma HMGIC fusion partner (218656_s_at), score: 0.3 LIFleukemia inhibitory factor (cholinergic differentiation factor) (205266_at), score: 0.38 LIMS1LIM and senescent cell antigen-like domains 1 (207198_s_at), score: 0.31 LITAFlipopolysaccharide-induced TNF factor (200706_s_at), score: 0.23 LMAN1lectin, mannose-binding, 1 (203294_s_at), score: 0.22 LMBRD1LMBR1 domain containing 1 (218191_s_at), score: 0.42 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: 0.39 LMOD1leiomodin 1 (smooth muscle) (203766_s_at), score: 0.19 LOC100128809similar to hCG2045829 (215707_s_at), score: 0.38 LRIG1leucine-rich repeats and immunoglobulin-like domains 1 (211596_s_at), score: 0.18 LRP1low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) (200784_s_at), score: 0.21 LTBP2latent transforming growth factor beta binding protein 2 (204682_at), score: 0.19 LTBRlymphotoxin beta receptor (TNFR superfamily, member 3) (203005_at), score: 0.19 LY96lymphocyte antigen 96 (206584_at), score: 0.26 LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog (202625_at), score: 0.23 MACF1microtubule-actin crosslinking factor 1 (208633_s_at), score: 0.19 MAFv-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) (209348_s_at), score: 0.3 MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 (209737_at), score: 0.29 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: 0.44 MAN2B1mannosidase, alpha, class 2B, member 1 (209166_s_at), score: 0.2 MAN2B2mannosidase, alpha, class 2B, member 2 (214703_s_at), score: 0.21 MANBAmannosidase, beta A, lysosomal (203778_at), score: 0.21 MAP1Smicrotubule-associated protein 1S (218522_s_at), score: 0.25 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: 0.24 MAP3K4mitogen-activated protein kinase kinase kinase 4 (216199_s_at), score: 0.25 MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (210284_s_at), score: 0.32 MAPK1mitogen-activated protein kinase 1 (208351_s_at), score: 0.19 MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2 (201461_s_at), score: 0.21 MARCH7membrane-associated ring finger (C3HC4) 7 (202654_x_at), score: 0.21 MAXMYC associated factor X (210734_x_at), score: 0.24 MEGF9multiple EGF-like-domains 9 (212830_at), score: 0.18 MEIS1Meis homeobox 1 (204069_at), score: 0.31 MEIS3P1Meis homeobox 3 pseudogene 1 (214077_x_at), score: 0.38 MEOX1mesenchyme homeobox 1 (205619_s_at), score: -0.76 MFAP4microfibrillar-associated protein 4 (212713_at), score: 0.37 MKS1Meckel syndrome, type 1 (218630_at), score: -0.78 MTSS1metastasis suppressor 1 (203037_s_at), score: 0.29 MYO1Dmyosin ID (212338_at), score: 0.19 NAB1NGFI-A binding protein 1 (EGR1 binding protein 1) (208047_s_at), score: 0.24 NACAP1nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 (211445_x_at), score: -0.81 NAMPTnicotinamide phosphoribosyltransferase (217738_at), score: 0.25 NEDD9neural precursor cell expressed, developmentally down-regulated 9 (202149_at), score: 0.18 NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (210162_s_at), score: 0.44 NFIL3nuclear factor, interleukin 3 regulated (203574_at), score: 0.19 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: 0.44 NID1nidogen 1 (202008_s_at), score: 0.45 NINJ1ninjurin 1 (203045_at), score: 0.32 NLRP1NLR family, pyrin domain containing 1 (218380_at), score: 0.19 NMD3NMD3 homolog (S. cerevisiae) (218036_x_at), score: 0.21 NOVA1neuro-oncological ventral antigen 1 (205794_s_at), score: -0.8 NPnucleoside phosphorylase (201695_s_at), score: 0.26 NPC1Niemann-Pick disease, type C1 (202679_at), score: 0.29 NPC2Niemann-Pick disease, type C2 (200701_at), score: 0.47 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: 0.27 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: 0.43 NRXN3neurexin 3 (205795_at), score: 0.24 OLFML2Aolfactomedin-like 2A (213075_at), score: 0.25 OS9osteosarcoma amplified 9, endoplasmic reticulum associated protein (200714_x_at), score: 0.22 OSMRoncostatin M receptor (205729_at), score: 0.19 OSTM1osteopetrosis associated transmembrane protein 1 (218196_at), score: 0.3 P2RX4purinergic receptor P2X, ligand-gated ion channel, 4 (204088_at), score: 0.23 PARP4poly (ADP-ribose) polymerase family, member 4 (202239_at), score: 0.18 PBX3pre-B-cell leukemia homeobox 3 (204082_at), score: 0.2 PCDH7protocadherin 7 (205534_at), score: 0.24 PCDHG@protocadherin gamma cluster (215836_s_at), score: 0.2 PCDHGA11protocadherin gamma subfamily A, 11 (211876_x_at), score: 0.24 PDCD1LG2programmed cell death 1 ligand 2 (220049_s_at), score: 0.21 PDE5Aphosphodiesterase 5A, cGMP-specific (206757_at), score: 0.22 PDGFAplatelet-derived growth factor alpha polypeptide (205463_s_at), score: 0.37 PDGFDplatelet derived growth factor D (219304_s_at), score: 0.31 PDLIM3PDZ and LIM domain 3 (209621_s_at), score: 0.29 PHTF2putative homeodomain transcription factor 2 (217097_s_at), score: 0.23 PI4KBphosphatidylinositol 4-kinase, catalytic, beta (206138_s_at), score: 0.19 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (203879_at), score: 0.2 PIONpigeon homolog (Drosophila) (222150_s_at), score: 0.23 PKP2plakophilin 2 (207717_s_at), score: 0.4 PLAURplasminogen activator, urokinase receptor (211924_s_at), score: 0.24 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: 0.49 POLR1Cpolymerase (RNA) I polypeptide C, 30kDa (207515_s_at), score: 0.21 PPAP2Aphosphatidic acid phosphatase type 2A (209147_s_at), score: 0.37 PPARDperoxisome proliferator-activated receptor delta (37152_at), score: 0.31 PROS1protein S (alpha) (207808_s_at), score: 0.26 PSAPprosaposin (200866_s_at), score: 0.19 PSMB8proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (209040_s_at), score: 0.23 PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) (204279_at), score: 0.22 PTGDSprostaglandin D2 synthase 21kDa (brain) (212187_x_at), score: 0.38 PTPN12protein tyrosine phosphatase, non-receptor type 12 (216915_s_at), score: 0.23 RAB5CRAB5C, member RAS oncogene family (201156_s_at), score: 0.2 RANBP2RAN binding protein 2 (201711_x_at), score: 0.32 RANBP9RAN binding protein 9 (202583_s_at), score: 0.24 RAPGEF2Rap guanine nucleotide exchange factor (GEF) 2 (203097_s_at), score: 0.19 RBMS1RNA binding motif, single stranded interacting protein 1 (209868_s_at), score: 0.2 RCAN2regulator of calcineurin 2 (203498_at), score: 0.34 RCL1RNA terminal phosphate cyclase-like 1 (218544_s_at), score: 0.26 RGPD5RANBP2-like and GRIP domain containing 5 (210676_x_at), score: 0.19 RGS2regulator of G-protein signaling 2, 24kDa (202388_at), score: 0.36 RIOK3RIO kinase 3 (yeast) (202129_s_at), score: 0.2 RNASET2ribonuclease T2 (217983_s_at), score: 0.22 RNF13ring finger protein 13 (201779_s_at), score: 0.2 RNF141ring finger protein 141 (219104_at), score: 0.21 RPL7P24ribosomal protein L7 pseudogene 24 (217092_x_at), score: -0.79 RPS4Y1ribosomal protein S4, Y-linked 1 (201909_at), score: 0.43 RRADRas-related associated with diabetes (204803_s_at), score: 0.52 RTN1reticulon 1 (203485_at), score: 0.21 RUNX1runt-related transcription factor 1 (209360_s_at), score: 0.36 SAT1spermidine/spermine N1-acetyltransferase 1 (213988_s_at), score: 0.25 SCARB1scavenger receptor class B, member 1 (201819_at), score: 0.28 SCARB2scavenger receptor class B, member 2 (201647_s_at), score: 0.28 SCG2secretogranin II (chromogranin C) (204035_at), score: 0.24 SCML2sex comb on midleg-like 2 (Drosophila) (206147_x_at), score: 0.21 SCPEP1serine carboxypeptidase 1 (218217_at), score: 0.19 SCYL2SCY1-like 2 (S. cerevisiae) (221220_s_at), score: 0.19 SEC23IPSEC23 interacting protein (216392_s_at), score: 0.23 SEMA5Asema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (205405_at), score: 0.22 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: 0.33 SETXsenataxin (201964_at), score: 0.23 SFRP1secreted frizzled-related protein 1 (202036_s_at), score: 0.27 SFRS2Bsplicing factor, arginine/serine-rich 2B (213152_s_at), score: 0.21 SFRS5splicing factor, arginine/serine-rich 5 (212266_s_at), score: 0.26 SGCEsarcoglycan, epsilon (204688_at), score: 0.19 SGPP1sphingosine-1-phosphate phosphatase 1 (221268_s_at), score: 0.27 SGSHN-sulfoglucosamine sulfohydrolase (35626_at), score: 0.23 SH3BGRLSH3 domain binding glutamic acid-rich protein like (201311_s_at), score: 0.29 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: 0.18 SKAP2src kinase associated phosphoprotein 2 (216899_s_at), score: 0.19 SLC10A3solute carrier family 10 (sodium/bile acid cotransporter family), member 3 (204928_s_at), score: 0.24 SLC19A2solute carrier family 19 (thiamine transporter), member 2 (209681_at), score: 0.34 SLC1A1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 (213664_at), score: 0.29 SLC20A2solute carrier family 20 (phosphate transporter), member 2 (202744_at), score: 0.27 SLC2A10solute carrier family 2 (facilitated glucose transporter), member 10 (221024_s_at), score: 0.21 SLC38A4solute carrier family 38, member 4 (220786_s_at), score: 0.18 SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 (209830_s_at), score: 0.19 SLCO3A1solute carrier organic anion transporter family, member 3A1 (219229_at), score: 0.18 SMOXspermine oxidase (210357_s_at), score: 0.24 SMURF1SMAD specific E3 ubiquitin protein ligase 1 (212666_at), score: 0.19 SOCS2suppressor of cytokine signaling 2 (203373_at), score: 0.19 SOX4SRY (sex determining region Y)-box 4 (201417_at), score: 0.31 SPATA20spermatogenesis associated 20 (218164_at), score: 0.2 SPRED2sprouty-related, EVH1 domain containing 2 (212458_at), score: 0.36 SPRY2sprouty homolog 2 (Drosophila) (204011_at), score: 0.32 SPRY4sprouty homolog 4 (Drosophila) (221489_s_at), score: 0.41 SQLEsqualene epoxidase (213562_s_at), score: 0.28 SQRDLsulfide quinone reductase-like (yeast) (217995_at), score: 0.23 SRFserum response factor (c-fos serum response element-binding transcription factor) (202401_s_at), score: 0.27 ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (208322_s_at), score: 0.2 STARD13StAR-related lipid transfer (START) domain containing 13 (213103_at), score: 0.2 STAT1signal transducer and activator of transcription 1, 91kDa (AFFX-HUMISGF3A/M97935_MA_at), score: 0.19 STBD1starch binding domain 1 (203986_at), score: 0.24 STK38Lserine/threonine kinase 38 like (212572_at), score: 0.36 STOMstomatin (201060_x_at), score: 0.33 SULF1sulfatase 1 (212353_at), score: 0.35 SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (213247_at), score: 0.31 TBL1XR1transducin (beta)-like 1 X-linked receptor 1 (221428_s_at), score: 0.22 TBX3T-box 3 (219682_s_at), score: 0.35 TCTN1tectonic family member 1 (218584_at), score: 0.19 TEX2testis expressed 2 (218099_at), score: 0.35 TFPItissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (209676_at), score: 0.22 TGFBR1transforming growth factor, beta receptor 1 (206943_at), score: 0.2 TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (201042_at), score: 0.23 TM2D1TM2 domain containing 1 (211703_s_at), score: 0.48 TM6SF1transmembrane 6 superfamily member 1 (219892_at), score: 0.33 TMBIM4transmembrane BAX inhibitor motif containing 4 (219206_x_at), score: 0.23 TMEM39Atransmembrane protein 39A (218615_s_at), score: 0.26 TMEM41Btransmembrane protein 41B (212623_at), score: 0.47 TMEM51transmembrane protein 51 (218815_s_at), score: 0.2 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (202510_s_at), score: 0.37 TNFRSF11Btumor necrosis factor receptor superfamily, member 11b (204933_s_at), score: 0.41 TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (207426_s_at), score: 0.36 TNS3tensin 3 (217853_at), score: 0.29 TOR1AIP1torsin A interacting protein 1 (216100_s_at), score: 0.21 TP53BP2tumor protein p53 binding protein, 2 (203120_at), score: 0.24 TP53I11tumor protein p53 inducible protein 11 (214667_s_at), score: 0.38 TPD52tumor protein D52 (201690_s_at), score: 0.26 TPD52L1tumor protein D52-like 1 (203786_s_at), score: 0.21 TPP1tripeptidyl peptidase I (200742_s_at), score: 0.62 TPST1tyrosylprotein sulfotransferase 1 (204140_at), score: 0.37 TPST2tyrosylprotein sulfotransferase 2 (204079_at), score: 0.24 TRAF3TNF receptor-associated factor 3 (221571_at), score: 0.21 TRAF3IP2TRAF3 interacting protein 2 (215411_s_at), score: 0.2 TRIB1tribbles homolog 1 (Drosophila) (202241_at), score: 0.42 TRIM22tripartite motif-containing 22 (213293_s_at), score: 0.33 TRIM32tripartite motif-containing 32 (203846_at), score: 0.22 TTPALtocopherol (alpha) transfer protein-like (219633_at), score: 0.26 UBA7ubiquitin-like modifier activating enzyme 7 (203281_s_at), score: 0.18 UBE3Bubiquitin protein ligase E3B (212403_at), score: 0.25 UBXN4UBX domain protein 4 (212008_at), score: 0.2 UTP3UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) (209486_at), score: 0.26 VDRvitamin D (1,25- dihydroxyvitamin D3) receptor (204255_s_at), score: 0.19 VEGFAvascular endothelial growth factor A (211527_x_at), score: 0.42 VEGFBvascular endothelial growth factor B (203683_s_at), score: 0.23 WACWW domain containing adaptor with coiled-coil (219679_s_at), score: 0.23 WT1Wilms tumor 1 (206067_s_at), score: 0.23 WTAPWilms tumor 1 associated protein (210285_x_at), score: 0.31 WWTR1WW domain containing transcription regulator 1 (202132_at), score: 0.31 YIPF6Yip1 domain family, member 6 (212341_at), score: 0.3 YRDCyrdC domain containing (E. coli) (218647_s_at), score: 0.28 ZEB1zinc finger E-box binding homeobox 1 (212758_s_at), score: 0.24 ZKSCAN3zinc finger with KRAB and SCAN domains 3 (211773_s_at), score: -0.77 ZMYM6zinc finger, MYM-type 6 (219924_s_at), score: 0.28 ZNF143zinc finger protein 143 (221873_at), score: 0.2 ZNF282zinc finger protein 282 (212892_at), score: 0.21 ZNF35zinc finger protein 35 (206096_at), score: 0.31 ZNF672zinc finger protein 672 (218068_s_at), score: 0.24 ZNF804Azinc finger protein 804A (215767_at), score: 0.19

Non-Entrez genes

Unknown, score:

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
1Twin.CEL	1	2	DS-twin	hgu133plus2	Down	DS-twin 1
6Twin.CEL	6	2	DS-twin	hgu133plus2	none	DS-twin 6
5CTwin.CEL	5	2	DS-twin	hgu133plus2	Down	DS-twin 5
2Twin.CEL	2	2	DS-twin	hgu133plus2	none	DS-twin 2
4Twin.CEL	4	2	DS-twin	hgu133plus2	none	DS-twin 4
46A.CEL	1	3	DS-mosaic	hgu133plus2	none	DS-mosaic 1