Previous module | Next module Module #151, TG: 2.6, TC: 3, 65 probes, 65 Entrez genes, 3 conditions

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Expression data for module #151

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

histidine metabolic process

The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

humoral immune response

An immune response mediated through a body fluid.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

histidine family amino acid metabolic process

The chemical reactions and pathways involving amino acids of the histidine family.

amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

carboxylic acid metabolic process

The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

cellular amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

small molecule metabolic process

The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass.

heterocycle metabolic process

The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

all

NA

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

cellular amino acid and derivative metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

cellular amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

cellular amino acid metabolic process

The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.

histidine metabolic process

The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

external side of plasma membrane

The side of the plasma membrane that is opposite to the side that faces the cytoplasm.

cell surface

The external part of the cell wall and/or plasma membrane.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

membrane-enclosed lumen

The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

vesicle lumen

The volume enclosed by the membrane or protein that forms a vesicle.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

organelle lumen

The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

cytoplasmic membrane-bounded vesicle lumen

The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

organelle lumen

The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

vesicle lumen

The volume enclosed by the membrane or protein that forms a vesicle.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic membrane-bounded vesicle lumen

The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

external side of plasma membrane

The side of the plasma membrane that is opposite to the side that faces the cytoplasm.

cytoplasmic membrane-bounded vesicle lumen

The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04610 1.761e-03 0.3673 5
21 Complement and coagulation cascades

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ALG9asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae) (ENSG00000086848), score: 0.65 ANKRD22ankyrin repeat domain 22 (ENSG00000152766), score: 0.67 AQP8aquaporin 8 (ENSG00000103375), score: 0.63 BMP10bone morphogenetic protein 10 (ENSG00000163217), score: 0.67 BMPERBMP binding endothelial regulator (ENSG00000164619), score: 0.65 BPIL3bactericidal/permeability-increasing protein-like 3 (ENSG00000167104), score: 0.93 BST1bone marrow stromal cell antigen 1 (ENSG00000109743), score: 0.62 C8Acomplement component 8, alpha polypeptide (ENSG00000157131), score: 0.63 C8Bcomplement component 8, beta polypeptide (ENSG00000021852), score: 0.65 C9orf72chromosome 9 open reading frame 72 (ENSG00000147894), score: 0.62 CCNL1cyclin L1 (ENSG00000163660), score: 0.65 CLDN14claudin 14 (ENSG00000159261), score: 0.71 CNGA1cyclic nucleotide gated channel alpha 1 (ENSG00000198515), score: 0.63 COLEC10collectin sub-family member 10 (C-type lectin) (ENSG00000184374), score: 0.66 CPB2carboxypeptidase B2 (plasma) (ENSG00000080618), score: 0.65 CYTIPcytohesin 1 interacting protein (ENSG00000115165), score: 0.65 DBHdopamine beta-hydroxylase (dopamine beta-monooxygenase) (ENSG00000123454), score: 0.64 DHODHdihydroorotate dehydrogenase (ENSG00000102967), score: 0.84 FAM83Afamily with sequence similarity 83, member A (ENSG00000147689), score: 1 FGBfibrinogen beta chain (ENSG00000171564), score: 0.64 FGGfibrinogen gamma chain (ENSG00000171557), score: 0.65 FOXF1forkhead box F1 (ENSG00000103241), score: 0.62 FSTfollistatin (ENSG00000134363), score: 0.77 GADD45Bgrowth arrest and DNA-damage-inducible, beta (ENSG00000099860), score: 0.63 GPR183G protein-coupled receptor 183 (ENSG00000169508), score: 0.74 GPR97G protein-coupled receptor 97 (ENSG00000182885), score: 0.91 GRAP2GRB2-related adaptor protein 2 (ENSG00000100351), score: 0.78 HALhistidine ammonia-lyase (ENSG00000084110), score: 0.61 HGFhepatocyte growth factor (hepapoietin A; scatter factor) (ENSG00000019991), score: 0.66 IL18RAPinterleukin 18 receptor accessory protein (ENSG00000115607), score: 0.94 IL1R2interleukin 1 receptor, type II (ENSG00000115590), score: 0.8 IL2RBinterleukin 2 receptor, beta (ENSG00000100385), score: 0.63 IL7Rinterleukin 7 receptor (ENSG00000168685), score: 0.66 IRF4interferon regulatory factor 4 (ENSG00000137265), score: 0.67 ITKIL2-inducible T-cell kinase (ENSG00000113263), score: 0.77 KCTD2potassium channel tetramerisation domain containing 2 (ENSG00000180901), score: -0.68 KIAA0146KIAA0146 (ENSG00000164808), score: 0.61 LOC100292202similar to solute carrier family 25, member 25 (ENSG00000148339), score: 0.65 MTHFD2Lmethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like (ENSG00000163738), score: 0.89 MXD1MAX dimerization protein 1 (ENSG00000059728), score: 0.64 MYO1Bmyosin IB (ENSG00000128641), score: 0.61 MYO1Fmyosin IF (ENSG00000142347), score: 0.68 NCF4neutrophil cytosolic factor 4, 40kDa (ENSG00000100365), score: 0.64 NRBF2nuclear receptor binding factor 2 (ENSG00000148572), score: 0.74 NT5M5',3'-nucleotidase, mitochondrial (ENSG00000205309), score: -0.67 OIT3oncoprotein induced transcript 3 (ENSG00000138315), score: 0.69 PRDM1PR domain containing 1, with ZNF domain (ENSG00000057657), score: 0.71 RHOHras homolog gene family, member H (ENSG00000168421), score: 0.61 RND3Rho family GTPase 3 (ENSG00000115963), score: 0.65 S1PR4sphingosine-1-phosphate receptor 4 (ENSG00000125910), score: 0.73 SAMSN1SAM domain, SH3 domain and nuclear localization signals 1 (ENSG00000155307), score: 0.83 SERPINA10serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 (ENSG00000140093), score: 0.69 SIK1salt-inducible kinase 1 (ENSG00000142178), score: 0.61 SLC13A5solute carrier family 13 (sodium-dependent citrate transporter), member 5 (ENSG00000141485), score: 0.69 SLC20A1solute carrier family 20 (phosphate transporter), member 1 (ENSG00000144136), score: 0.63 TATtyrosine aminotransferase (ENSG00000198650), score: 0.63 TDO2tryptophan 2,3-dioxygenase (ENSG00000151790), score: 0.64 TEFthyrotrophic embryonic factor (ENSG00000167074), score: -0.63 TGDSTDP-glucose 4,6-dehydratase (ENSG00000088451), score: 0.68 TMED6transmembrane emp24 protein transport domain containing 6 (ENSG00000157315), score: 0.74 TOB1transducer of ERBB2, 1 (ENSG00000141232), score: 0.76 TRAT1T cell receptor associated transmembrane adaptor 1 (ENSG00000163519), score: 0.68 TRPM8transient receptor potential cation channel, subfamily M, member 8 (ENSG00000144481), score: 0.67 TTPALtocopherol (alpha) transfer protein-like (ENSG00000124120), score: 0.66 USP2ubiquitin specific peptidase 2 (ENSG00000036672), score: -0.7

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id species tissue sex individual
ppa_lv_f_ca1 ppa lv f _
ppy_lv_m_ca1 ppy lv m _
ppy_lv_f_ca1 ppy lv f _

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