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Expression data for module #637

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

potassium ion transport

The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

neurotransmitter transport

The directed movement of a neurotransmitter into, out of, within or between cells by means of some external agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

synaptic transmission

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

nerve-nerve synaptic transmission

The process of communication from a neuron to another neuron across a synapse.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

nervous system development

The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

neurogenesis

Generation of cells within the nervous system.

signaling process

Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.

signaling

The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.

signal transmission

The process whereby a signal is released and/or conveyed from one location to another.

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

neuron differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a neuron.

regulation of neurological system process

Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

generation of neurons

The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of synaptic transmission

Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of transmission of nerve impulse

Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

NA

signaling process

Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

synaptic transmission

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

regulation of transmission of nerve impulse

Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

regulation of neurological system process

Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.

regulation of synaptic transmission

Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

regulation of transmission of nerve impulse

Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.

neurogenesis

Generation of cells within the nervous system.

neuron differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a neuron.

potassium ion transport

The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoskeleton

Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

cell cortex

The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.

synaptic vesicle

A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.

spectrin

Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins.

endomembrane system

A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.

vesicle membrane

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

postsynaptic density

The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.

actin cytoskeleton

The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cell junction

A plasma membrane part that forms a specialized region of connection between two cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.

coated vesicle

Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.

clathrin-coated vesicle

A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.

dendrite

A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

coated vesicle membrane

The lipid bilayer surrounding a coated vesicle.

clathrin coated vesicle membrane

The lipid bilayer surrounding a clathrin-coated vesicle.

synaptic vesicle membrane

The lipid bilayer surrounding a synaptic vesicle.

cortical cytoskeleton

The portion of the cytoskeleton that lies just beneath the plasma membrane.

cortical actin cytoskeleton

The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.

organelle membrane

The lipid bilayer surrounding an organelle.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

neuron projection

A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cell cortex part

Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.

synapse part

Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

synapse

The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

synapse part

Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

organelle membrane

The lipid bilayer surrounding an organelle.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

organelle membrane

The lipid bilayer surrounding an organelle.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.

vesicle membrane

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle membrane

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

postsynaptic density

The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic vesicle part

Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

spectrin

Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins.

cell cortex part

Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.

spectrin

Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins.

cortical cytoskeleton

The portion of the cytoskeleton that lies just beneath the plasma membrane.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

coated vesicle membrane

The lipid bilayer surrounding a coated vesicle.

cortical actin cytoskeleton

The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.

cortical actin cytoskeleton

The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.

synaptic vesicle

A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.

clathrin coated vesicle membrane

The lipid bilayer surrounding a clathrin-coated vesicle.

synaptic vesicle membrane

The lipid bilayer surrounding a synaptic vesicle.

Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

ionotropic glutamate receptor activity

Combining with glutamate to initiate a change in cell activity through the regulation of ion channels.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

extracellular ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.

excitatory extracellular ligand-gated ion channel activity

NA

extracellular-glutamate-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.

voltage-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

potassium channel activity

Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

glutamate receptor activity

Combining with glutamate to initiate a change in cell activity.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

passive transmembrane transporter activity

Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.

voltage-gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

ligand-gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

voltage-gated cation channel activity

Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

voltage-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

voltage-gated cation channel activity

Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04010 2.192e-02 6.523 16
103 MAPK signaling pathway
04720 2.677e-02 1.583 7
25 Long-term potentiation
05014 3.907e-02 1.267 6
20 Amyotrophic lateral sclerosis (ALS)
04080 4.578e-02 6.46 15
102 Neuroactive ligand-receptor interaction

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (ENSG00000006071), score: 0.51 ABCG4ATP-binding cassette, sub-family G (WHITE), member 4 (ENSG00000172350), score: 0.58 ACAA2acetyl-CoA acyltransferase 2 (ENSG00000167315), score: -0.55 ACADSacyl-CoA dehydrogenase, C-2 to C-3 short chain (ENSG00000122971), score: -0.51 ACSL6acyl-CoA synthetase long-chain family member 6 (ENSG00000164398), score: 0.48 ADAM22ADAM metallopeptidase domain 22 (ENSG00000008277), score: 0.65 ADCY8adenylate cyclase 8 (brain) (ENSG00000155897), score: 0.49 AKAP13A kinase (PRKA) anchor protein 13 (ENSG00000170776), score: -0.61 ANTXR2anthrax toxin receptor 2 (ENSG00000163297), score: -0.52 AP3B2adaptor-related protein complex 3, beta 2 subunit (ENSG00000103723), score: 0.53 APPL2adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (ENSG00000136044), score: 0.55 AQP4aquaporin 4 (ENSG00000171885), score: 0.52 ARHGAP44Rho GTPase activating protein 44 (ENSG00000006740), score: 0.46 ARID1BAT rich interactive domain 1B (SWI1-like) (ENSG00000049618), score: 0.49 ARPC2actin related protein 2/3 complex, subunit 2, 34kDa (ENSG00000163466), score: -0.62 ARPP21cAMP-regulated phosphoprotein, 21kDa (ENSG00000172995), score: 0.56 ASAMadipocyte-specific adhesion molecule (ENSG00000166250), score: 0.51 ASTN1astrotactin 1 (ENSG00000152092), score: 0.47 ATP6V0E1ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 (ENSG00000113732), score: -0.53 ATP8B1ATPase, aminophospholipid transporter, class I, type 8B, member 1 (ENSG00000081923), score: -0.52 B4GALT6UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 (ENSG00000118276), score: 0.52 BAHCC1BAH domain and coiled-coil containing 1 (ENSG00000171282), score: 0.51 BCANbrevican (ENSG00000132692), score: 0.5 BICD1bicaudal D homolog 1 (Drosophila) (ENSG00000151746), score: 0.63 BPTFbromodomain PHD finger transcription factor (ENSG00000171634), score: 0.6 BRP44brain protein 44 (ENSG00000143158), score: -0.56 BTBD3BTB (POZ) domain containing 3 (ENSG00000132640), score: 0.59 C11orf41chromosome 11 open reading frame 41 (ENSG00000110427), score: 0.5 C12orf51chromosome 12 open reading frame 51 (ENSG00000173064), score: 0.47 C12orf53chromosome 12 open reading frame 53 (ENSG00000139200), score: 0.47 C13orf23chromosome 13 open reading frame 23 (ENSG00000120685), score: 0.53 C15orf27chromosome 15 open reading frame 27 (ENSG00000169758), score: 0.72 C17orf28chromosome 17 open reading frame 28 (ENSG00000167861), score: 0.52 C3orf58chromosome 3 open reading frame 58 (ENSG00000181744), score: 0.49 C6orf115chromosome 6 open reading frame 115 (ENSG00000146386), score: -0.63 C6orf174chromosome 6 open reading frame 174 (ENSG00000214338), score: 0.54 C7orf16chromosome 7 open reading frame 16 (ENSG00000106341), score: 0.74 C8orf79chromosome 8 open reading frame 79 (ENSG00000170941), score: 0.75 C9orf4chromosome 9 open reading frame 4 (ENSG00000136805), score: 0.57 CA10carbonic anhydrase X (ENSG00000154975), score: 0.63 CA8carbonic anhydrase VIII (ENSG00000178538), score: 0.73 CACNA1Bcalcium channel, voltage-dependent, N type, alpha 1B subunit (ENSG00000148408), score: 0.5 CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit (ENSG00000006283), score: 0.55 CACNA1Icalcium channel, voltage-dependent, T type, alpha 1I subunit (ENSG00000100346), score: 0.59 CACNB4calcium channel, voltage-dependent, beta 4 subunit (ENSG00000182389), score: 0.64 CACNG2calcium channel, voltage-dependent, gamma subunit 2 (ENSG00000166862), score: 0.6 CADM2cell adhesion molecule 2 (ENSG00000175161), score: 0.48 CADM4cell adhesion molecule 4 (ENSG00000105767), score: 0.48 CALB1calbindin 1, 28kDa (ENSG00000104327), score: 0.48 CAMKK2calcium/calmodulin-dependent protein kinase kinase 2, beta (ENSG00000110931), score: 0.59 CAMSAP1L1calmodulin regulated spectrin-associated protein 1-like 1 (ENSG00000118200), score: 0.48 CASP7caspase 7, apoptosis-related cysteine peptidase (ENSG00000165806), score: -0.55 CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 3 (ENSG00000129993), score: 0.51 CBLN1cerebellin 1 precursor (ENSG00000102924), score: 0.91 CCDC109Acoiled-coil domain containing 109A (ENSG00000156026), score: 0.56 CCNJLcyclin J-like (ENSG00000135083), score: 0.47 CCNT2cyclin T2 (ENSG00000082258), score: 0.47 CDC42BPACDC42 binding protein kinase alpha (DMPK-like) (ENSG00000143776), score: 0.47 CDH18cadherin 18, type 2 (ENSG00000145526), score: 0.52 CDH7cadherin 7, type 2 (ENSG00000081138), score: 0.77 CDONCdon homolog (mouse) (ENSG00000064309), score: 0.52 CDR2Lcerebellar degeneration-related protein 2-like (ENSG00000109089), score: 0.52 CDS2CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 (ENSG00000101290), score: 0.54 CERKLceramide kinase-like (ENSG00000188452), score: 0.57 CHD6chromodomain helicase DNA binding protein 6 (ENSG00000124177), score: 0.49 CHD9chromodomain helicase DNA binding protein 9 (ENSG00000177200), score: 0.57 CHGBchromogranin B (secretogranin 1) (ENSG00000089199), score: 0.65 CHN2chimerin (chimaerin) 2 (ENSG00000106069), score: 0.67 CHRNA3cholinergic receptor, nicotinic, alpha 3 (ENSG00000080644), score: 0.61 CLSTN3calsyntenin 3 (ENSG00000139182), score: 0.48 CLVS1clavesin 1 (ENSG00000177182), score: 0.56 CLVS2clavesin 2 (ENSG00000146352), score: 0.67 CNKSR2connector enhancer of kinase suppressor of Ras 2 (ENSG00000149970), score: 0.57 CNNM1cyclin M1 (ENSG00000119946), score: 0.52 CNOT2CCR4-NOT transcription complex, subunit 2 (ENSG00000111596), score: 0.51 CNR1cannabinoid receptor 1 (brain) (ENSG00000118432), score: 0.64 CNTN2contactin 2 (axonal) (ENSG00000184144), score: 0.5 CNTN4contactin 4 (ENSG00000144619), score: 0.48 CNTN6contactin 6 (ENSG00000134115), score: 0.65 CNTNAP1contactin associated protein 1 (ENSG00000108797), score: 0.57 COL3A1collagen, type III, alpha 1 (ENSG00000168542), score: -0.5 COL6A2collagen, type VI, alpha 2 (ENSG00000142173), score: -0.49 CORO2Bcoronin, actin binding protein, 2B (ENSG00000103647), score: 0.51 CRHR1corticotropin releasing hormone receptor 1 (ENSG00000120088), score: 0.66 CRTAMcytotoxic and regulatory T cell molecule (ENSG00000109943), score: 0.76 CTCFCCCTC-binding factor (zinc finger protein) (ENSG00000102974), score: 0.5 CYR61cysteine-rich, angiogenic inducer, 61 (ENSG00000142871), score: -0.52 DAB1disabled homolog 1 (Drosophila) (ENSG00000173406), score: 0.55 DBC1deleted in bladder cancer 1 (ENSG00000078725), score: 0.52 DCAF6DDB1 and CUL4 associated factor 6 (ENSG00000143164), score: -0.49 DGKEdiacylglycerol kinase, epsilon 64kDa (ENSG00000153933), score: 0.48 DGKIdiacylglycerol kinase, iota (ENSG00000157680), score: 0.47 DHRS3dehydrogenase/reductase (SDR family) member 3 (ENSG00000162496), score: -0.51 DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila) (ENSG00000160305), score: 0.51 DNERdelta/notch-like EGF repeat containing (ENSG00000187957), score: 0.5 DNM3dynamin 3 (ENSG00000197959), score: 0.62 DNMT3ADNA (cytosine-5-)-methyltransferase 3 alpha (ENSG00000119772), score: 0.48 DOPEY2dopey family member 2 (ENSG00000142197), score: 0.61 DPP6dipeptidyl-peptidase 6 (ENSG00000130226), score: 0.53 DUSP6dual specificity phosphatase 6 (ENSG00000139318), score: -0.5 DYNC1I1dynein, cytoplasmic 1, intermediate chain 1 (ENSG00000158560), score: 0.49 EBF1early B-cell factor 1 (ENSG00000164330), score: 0.59 ECE2endothelin converting enzyme 2 (ENSG00000145194), score: 0.62 EFR3BEFR3 homolog B (S. cerevisiae) (ENSG00000084710), score: 0.55 ELF1E74-like factor 1 (ets domain transcription factor) (ENSG00000120690), score: -0.56 ELMOD1ELMO/CED-12 domain containing 1 (ENSG00000110675), score: 0.49 ELOVL4elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 (ENSG00000118402), score: 0.52 EN1engrailed homeobox 1 (ENSG00000163064), score: 0.51 EPB41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) (ENSG00000159023), score: 0.53 EPC1enhancer of polycomb homolog 1 (Drosophila) (ENSG00000120616), score: 0.67 EPC2enhancer of polycomb homolog 2 (Drosophila) (ENSG00000135999), score: 0.47 EPHA8EPH receptor A8 (ENSG00000070886), score: 0.55 ERBB2IPerbb2 interacting protein (ENSG00000112851), score: -0.54 ETV6ets variant 6 (ENSG00000139083), score: -0.52 FAIM2Fas apoptotic inhibitory molecule 2 (ENSG00000135472), score: 0.51 FAM131Bfamily with sequence similarity 131, member B (ENSG00000159784), score: 0.56 FAM135Bfamily with sequence similarity 135, member B (ENSG00000147724), score: 0.47 FAM171Bfamily with sequence similarity 171, member B (ENSG00000144369), score: 0.48 FAT2FAT tumor suppressor homolog 2 (Drosophila) (ENSG00000086570), score: 1 FGF14fibroblast growth factor 14 (ENSG00000102466), score: 0.53 FGF3fibroblast growth factor 3 (ENSG00000186895), score: 0.5 FGF5fibroblast growth factor 5 (ENSG00000138675), score: 0.83 FGF9fibroblast growth factor 9 (glia-activating factor) (ENSG00000102678), score: 0.52 FGFR1fibroblast growth factor receptor 1 (ENSG00000077782), score: 0.55 FHDC1FH2 domain containing 1 (ENSG00000137460), score: 0.54 FKBP5FK506 binding protein 5 (ENSG00000096060), score: -0.56 FKBP9FK506 binding protein 9, 63 kDa (ENSG00000122642), score: -0.52 FLT3fms-related tyrosine kinase 3 (ENSG00000122025), score: 0.58 FNDC5fibronectin type III domain containing 5 (ENSG00000160097), score: 0.49 FOXO3forkhead box O3 (ENSG00000118689), score: 0.47 FUT9fucosyltransferase 9 (alpha (1,3) fucosyltransferase) (ENSG00000172461), score: 0.56 FZD7frizzled homolog 7 (Drosophila) (ENSG00000155760), score: 0.59 GABRA1gamma-aminobutyric acid (GABA) A receptor, alpha 1 (ENSG00000022355), score: 0.58 GABRB2gamma-aminobutyric acid (GABA) A receptor, beta 2 (ENSG00000145864), score: 0.59 GABRG2gamma-aminobutyric acid (GABA) A receptor, gamma 2 (ENSG00000113327), score: 0.52 GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (ENSG00000136750), score: 0.48 GALK2galactokinase 2 (ENSG00000156958), score: -0.49 GALNT7UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) (ENSG00000109586), score: 0.69 GARNL3GTPase activating Rap/RanGAP domain-like 3 (ENSG00000136895), score: 0.53 GCFC1GC-rich sequence DNA-binding factor 1 (ENSG00000159086), score: 0.5 GDF10growth differentiation factor 10 (ENSG00000107623), score: 0.61 GHITMgrowth hormone inducible transmembrane protein (ENSG00000165678), score: -0.6 GLCEglucuronic acid epimerase (ENSG00000138604), score: 0.46 GLRA1glycine receptor, alpha 1 (ENSG00000145888), score: 0.52 GLRA2glycine receptor, alpha 2 (ENSG00000101958), score: 0.56 GNG13guanine nucleotide binding protein (G protein), gamma 13 (ENSG00000127588), score: 0.69 GPM6Aglycoprotein M6A (ENSG00000150625), score: 0.55 GPM6Bglycoprotein M6B (ENSG00000046653), score: 0.48 GPR37L1G protein-coupled receptor 37 like 1 (ENSG00000170075), score: 0.56 GRB14growth factor receptor-bound protein 14 (ENSG00000115290), score: -0.5 GRIA1glutamate receptor, ionotropic, AMPA 1 (ENSG00000155511), score: 0.55 GRIA2glutamate receptor, ionotropic, AMPA 2 (ENSG00000120251), score: 0.51 GRIA4glutamate receptor, ionotrophic, AMPA 4 (ENSG00000152578), score: 0.68 GRID2glutamate receptor, ionotropic, delta 2 (ENSG00000152208), score: 0.88 GRIK1glutamate receptor, ionotropic, kainate 1 (ENSG00000171189), score: 0.57 GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 (ENSG00000176884), score: 0.52 GRM1glutamate receptor, metabotropic 1 (ENSG00000152822), score: 0.77 HADHhydroxyacyl-CoA dehydrogenase (ENSG00000138796), score: -0.52 HCN1hyperpolarization activated cyclic nucleotide-gated potassium channel 1 (ENSG00000164588), score: 0.55 HIVEP2human immunodeficiency virus type I enhancer binding protein 2 (ENSG00000010818), score: 0.47 IFFO2intermediate filament family orphan 2 (ENSG00000169991), score: 0.51 IGSF21immunoglobin superfamily, member 21 (ENSG00000117154), score: 0.52 ITPRIPinositol 1,4,5-triphosphate receptor interacting protein (ENSG00000148841), score: -0.5 JAKMIP2janus kinase and microtubule interacting protein 2 (ENSG00000176049), score: 0.53 JARID2jumonji, AT rich interactive domain 2 (ENSG00000008083), score: 0.59 JMJD1Cjumonji domain containing 1C (ENSG00000171988), score: 0.52 KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (ENSG00000111262), score: 0.66 KCNC1potassium voltage-gated channel, Shaw-related subfamily, member 1 (ENSG00000129159), score: 0.72 KCND3potassium voltage-gated channel, Shal-related subfamily, member 3 (ENSG00000171385), score: 0.54 KCNIP1Kv channel interacting protein 1 (ENSG00000182132), score: 0.48 KCNJ6potassium inwardly-rectifying channel, subfamily J, member 6 (ENSG00000157542), score: 0.57 KCNK1potassium channel, subfamily K, member 1 (ENSG00000135750), score: 0.47 KCNK10potassium channel, subfamily K, member 10 (ENSG00000100433), score: 0.75 KCNK9potassium channel, subfamily K, member 9 (ENSG00000169427), score: 0.79 KCNQ2potassium voltage-gated channel, KQT-like subfamily, member 2 (ENSG00000075043), score: 0.5 KCNT1potassium channel, subfamily T, member 1 (ENSG00000107147), score: 0.59 KCTD2potassium channel tetramerisation domain containing 2 (ENSG00000180901), score: 0.51 KIAA0240KIAA0240 (ENSG00000112624), score: 0.53 KIAA1217KIAA1217 (ENSG00000120549), score: -0.58 KIAA1409KIAA1409 (ENSG00000133958), score: 0.57 KIF1Akinesin family member 1A (ENSG00000130294), score: 0.48 KIF1Bkinesin family member 1B (ENSG00000054523), score: 0.52 KIF5Ckinesin family member 5C (ENSG00000168280), score: 0.52 KIRREL3kin of IRRE like 3 (Drosophila) (ENSG00000149571), score: 0.46 KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (ENSG00000157404), score: 0.5 KRT222keratin 222 (ENSG00000213424), score: 0.53 LAP3leucine aminopeptidase 3 (ENSG00000002549), score: -0.49 LDB2LIM domain binding 2 (ENSG00000169744), score: -0.57 LGI2leucine-rich repeat LGI family, member 2 (ENSG00000153012), score: 0.6 LIN7Alin-7 homolog A (C. elegans) (ENSG00000111052), score: 0.5 LOC100131509similar to inward rectifying K+ channel negative regulator Kir2.2v (ENSG00000184185), score: 0.61 LOC100134209similar to IQ motif and Sec7 domain-containing protein 3 (ENSG00000120645), score: 0.54 LOC100293817similar to hCG1811893 (ENSG00000144460), score: 0.52 LOC100294337hypothetical protein LOC100294337 (ENSG00000120071), score: 0.49 LRCH1leucine-rich repeats and calponin homology (CH) domain containing 1 (ENSG00000136141), score: 0.69 LRP8low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (ENSG00000157193), score: 0.54 LRRC26leucine rich repeat containing 26 (ENSG00000184709), score: 0.49 LRRC38leucine rich repeat containing 38 (ENSG00000162494), score: 0.69 LRRC3Bleucine rich repeat containing 3B (ENSG00000179796), score: 0.61 LRRN1leucine rich repeat neuronal 1 (ENSG00000175928), score: 0.55 LRRTM3leucine rich repeat transmembrane neuronal 3 (ENSG00000198739), score: 0.54 LSAMPlimbic system-associated membrane protein (ENSG00000185565), score: 0.49 LTBP1latent transforming growth factor beta binding protein 1 (ENSG00000049323), score: -0.51 MAB21L1mab-21-like 1 (C. elegans) (ENSG00000180660), score: 0.99 MAML3mastermind-like 3 (Drosophila) (ENSG00000196782), score: 0.81 MAN2A1mannosidase, alpha, class 2A, member 1 (ENSG00000112893), score: -0.59 MAP1Bmicrotubule-associated protein 1B (ENSG00000131711), score: 0.47 MAP7D2MAP7 domain containing 2 (ENSG00000184368), score: 0.48 MAPK8IP3mitogen-activated protein kinase 8 interacting protein 3 (ENSG00000138834), score: 0.47 MCF2LMCF.2 cell line derived transforming sequence-like (ENSG00000126217), score: 0.48 MCTP1multiple C2 domains, transmembrane 1 (ENSG00000175471), score: 0.57 MDGA1MAM domain containing glycosylphosphatidylinositol anchor 1 (ENSG00000112139), score: 0.71 MEIS1Meis homeobox 1 (ENSG00000143995), score: 0.68 MLC1megalencephalic leukoencephalopathy with subcortical cysts 1 (ENSG00000100427), score: 0.55 MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) (ENSG00000118058), score: 0.61 MRPL33mitochondrial ribosomal protein L33 (ENSG00000158019), score: -0.54 MSX2msh homeobox 2 (ENSG00000120149), score: 0.52 MTSS1Lmetastasis suppressor 1-like (ENSG00000132613), score: 0.5 MYT1myelin transcription factor 1 (ENSG00000196132), score: 0.8 MYT1Lmyelin transcription factor 1-like (ENSG00000186487), score: 0.48 NALCNsodium leak channel, non-selective (ENSG00000102452), score: 0.5 NDPNorrie disease (pseudoglioma) (ENSG00000124479), score: 0.49 NEFMneurofilament, medium polypeptide (ENSG00000104722), score: 0.47 NKX6-3NK6 homeobox 3 (ENSG00000165066), score: 0.59 NMNAT2nicotinamide nucleotide adenylyltransferase 2 (ENSG00000157064), score: 0.59 NRG2neuregulin 2 (ENSG00000158458), score: 0.72 NRP1neuropilin 1 (ENSG00000099250), score: -0.64 NTMneurotrimin (ENSG00000182667), score: 0.59 NTRK3neurotrophic tyrosine kinase, receptor, type 3 (ENSG00000140538), score: 0.56 OLFM3olfactomedin 3 (ENSG00000118733), score: 0.55 PAG1phosphoprotein associated with glycosphingolipid microdomains 1 (ENSG00000076641), score: 0.57 PAK7p21 protein (Cdc42/Rac)-activated kinase 7 (ENSG00000101349), score: 0.59 PANX2pannexin 2 (ENSG00000073150), score: 0.51 PAQR8progestin and adipoQ receptor family member VIII (ENSG00000170915), score: 0.49 PAX3paired box 3 (ENSG00000135903), score: 0.64 PAX6paired box 6 (ENSG00000007372), score: 0.84 PAXIP1PAX interacting (with transcription-activation domain) protein 1 (ENSG00000157212), score: 0.5 PDZD7PDZ domain containing 7 (ENSG00000186862), score: 0.5 PHACTR3phosphatase and actin regulator 3 (ENSG00000087495), score: 0.48 PHIPpleckstrin homology domain interacting protein (ENSG00000146247), score: 0.52 PIK3R3phosphoinositide-3-kinase, regulatory subunit 3 (gamma) (ENSG00000117461), score: 0.56 PKDCCprotein kinase domain containing, cytoplasmic homolog (mouse) (ENSG00000162878), score: -0.55 PLBD1phospholipase B domain containing 1 (ENSG00000121316), score: -0.5 PLCB4phospholipase C, beta 4 (ENSG00000101333), score: 0.71 PLCXD3phosphatidylinositol-specific phospholipase C, X domain containing 3 (ENSG00000182836), score: 0.61 PLD5phospholipase D family, member 5 (ENSG00000180287), score: 0.65 PLEKHA2pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 (ENSG00000169499), score: -0.52 PLK2polo-like kinase 2 (ENSG00000145632), score: -0.51 PLP1proteolipid protein 1 (ENSG00000123560), score: 0.46 PPM1Hprotein phosphatase, Mg2+/Mn2+ dependent, 1H (ENSG00000111110), score: 0.53 PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozyme (ENSG00000138814), score: 0.53 PRDM10PR domain containing 10 (ENSG00000170325), score: 0.56 PRMT8protein arginine methyltransferase 8 (ENSG00000111218), score: 0.48 PRSS23protease, serine, 23 (ENSG00000150687), score: -0.51 PRUNE2prune homolog 2 (Drosophila) (ENSG00000106772), score: 0.49 PSD2pleckstrin and Sec7 domain containing 2 (ENSG00000146005), score: 0.59 PTCH1patched 1 (ENSG00000185920), score: 0.63 PTCHD1patched domain containing 1 (ENSG00000165186), score: 0.76 PTP4A2protein tyrosine phosphatase type IVA, member 2 (ENSG00000184007), score: -0.56 PTPRRprotein tyrosine phosphatase, receptor type, R (ENSG00000153233), score: 0.64 PVALBparvalbumin (ENSG00000100362), score: 0.66 PYGO1pygopus homolog 1 (Drosophila) (ENSG00000171016), score: 0.52 QARSglutaminyl-tRNA synthetase (ENSG00000172053), score: -0.52 RAB20RAB20, member RAS oncogene family (ENSG00000139832), score: -0.5 RAB9BRAB9B, member RAS oncogene family (ENSG00000123570), score: 0.5 RASGEF1CRasGEF domain family, member 1C (ENSG00000146090), score: 0.54 RBM9RNA binding motif protein 9 (ENSG00000100320), score: 0.51 RCAN3RCAN family member 3 (ENSG00000117602), score: 0.55 RGS7regulator of G-protein signaling 7 (ENSG00000182901), score: 0.5 RGS7BPregulator of G-protein signaling 7 binding protein (ENSG00000186479), score: 0.5 RGS8regulator of G-protein signaling 8 (ENSG00000135824), score: 0.64 RIMS4regulating synaptic membrane exocytosis 4 (ENSG00000101098), score: 0.51 RIPK2receptor-interacting serine-threonine kinase 2 (ENSG00000104312), score: -0.52 RIT2Ras-like without CAAX 2 (ENSG00000152214), score: 0.62 RMND5Arequired for meiotic nuclear division 5 homolog A (S. cerevisiae) (ENSG00000153561), score: 0.46 RNF182ring finger protein 182 (ENSG00000180537), score: 0.52 RORARAR-related orphan receptor A (ENSG00000069667), score: 0.47 RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5 (ENSG00000100784), score: 0.46 RTN1reticulon 1 (ENSG00000139970), score: 0.51 RUNX1T1runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (ENSG00000079102), score: 0.55 SART3squamous cell carcinoma antigen recognized by T cells 3 (ENSG00000075856), score: 0.5 SBK1SH3-binding domain kinase 1 (ENSG00000188322), score: 0.54 SCRN1secernin 1 (ENSG00000136193), score: 0.49 SEC11ASEC11 homolog A (S. cerevisiae) (ENSG00000140612), score: -0.5 SEL1L3sel-1 suppressor of lin-12-like 3 (C. elegans) (ENSG00000091490), score: 0.59 SERPINF1serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (ENSG00000132386), score: -0.5 SGSM1small G protein signaling modulator 1 (ENSG00000167037), score: 0.6 SHBSrc homology 2 domain containing adaptor protein B (ENSG00000107338), score: -0.52 SHFSrc homology 2 domain containing F (ENSG00000138606), score: 0.67 SIDT1SID1 transmembrane family, member 1 (ENSG00000072858), score: 0.48 SIK1salt-inducible kinase 1 (ENSG00000142178), score: -0.52 SKIv-ski sarcoma viral oncogene homolog (avian) (ENSG00000157933), score: 0.63 SKOR1SKI family transcriptional corepressor 1 (ENSG00000188779), score: 0.77 SLC12A5solute carrier family 12 (potassium/chloride transporter), member 5 (ENSG00000124140), score: 0.57 SLC1A3solute carrier family 1 (glial high affinity glutamate transporter), member 3 (ENSG00000079215), score: 0.56 SLC24A3solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 (ENSG00000185052), score: 0.5 SLC32A1solute carrier family 32 (GABA vesicular transporter), member 1 (ENSG00000101438), score: 0.54 SLC35F4solute carrier family 35, member F4 (ENSG00000151812), score: 0.79 SLC4A10solute carrier family 4, sodium bicarbonate transporter, member 10 (ENSG00000144290), score: 0.51 SLC6A17solute carrier family 6, member 17 (ENSG00000197106), score: 0.49 SLC6A5solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (ENSG00000165970), score: 0.65 SLC7A14solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 (ENSG00000013293), score: 0.59 SLC9A5solute carrier family 9 (sodium/hydrogen exchanger), member 5 (ENSG00000135740), score: 0.62 SLITRK4SLIT and NTRK-like family, member 4 (ENSG00000179542), score: 0.56 SNAP23synaptosomal-associated protein, 23kDa (ENSG00000092531), score: -0.54 SNAP25synaptosomal-associated protein, 25kDa (ENSG00000132639), score: 0.57 SNAP91synaptosomal-associated protein, 91kDa homolog (mouse) (ENSG00000065609), score: 0.55 SNED1sushi, nidogen and EGF-like domains 1 (ENSG00000162804), score: 0.52 SNRKSNF related kinase (ENSG00000163788), score: 0.58 SNX25sorting nexin 25 (ENSG00000109762), score: 0.61 SPHKAPSPHK1 interactor, AKAP domain containing (ENSG00000153820), score: 0.68 SPINK6serine peptidase inhibitor, Kazal type 6 (ENSG00000178172), score: 0.55 SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) (ENSG00000197694), score: 0.46 SPTBspectrin, beta, erythrocytic (ENSG00000070182), score: 0.51 SPTBN5spectrin, beta, non-erythrocytic 5 (ENSG00000137877), score: 0.53 SRCIN1SRC kinase signaling inhibitor 1 (ENSG00000017373), score: 0.57 SRGAP3SLIT-ROBO Rho GTPase activating protein 3 (ENSG00000196220), score: 0.58 SRRM4serine/arginine repetitive matrix 4 (ENSG00000139767), score: 0.62 STACSH3 and cysteine rich domain (ENSG00000144681), score: 0.62 STMN4stathmin-like 4 (ENSG00000015592), score: 0.48 STXBP1syntaxin binding protein 1 (ENSG00000136854), score: 0.54 SULT4A1sulfotransferase family 4A, member 1 (ENSG00000130540), score: 0.49 SV2Bsynaptic vesicle glycoprotein 2B (ENSG00000185518), score: 0.51 SYBUsyntabulin (syntaxin-interacting) (ENSG00000147642), score: 0.55 SYN2synapsin II (ENSG00000157152), score: 0.49 SYNPRsynaptoporin (ENSG00000163630), score: 0.51 SYT11synaptotagmin XI (ENSG00000132718), score: 0.51 SYT12synaptotagmin XII (ENSG00000173227), score: 0.54 SYT4synaptotagmin IV (ENSG00000132872), score: 0.65 TAGLN3transgelin 3 (ENSG00000144834), score: 0.51 TBC1D30TBC1 domain family, member 30 (ENSG00000111490), score: 0.48 TBC1D9TBC1 domain family, member 9 (with GRAM domain) (ENSG00000109436), score: 0.58 TCF21transcription factor 21 (ENSG00000118526), score: -0.5 TEAD3TEA domain family member 3 (ENSG00000007866), score: -0.5 TGFBItransforming growth factor, beta-induced, 68kDa (ENSG00000120708), score: -0.51 TIAM1T-cell lymphoma invasion and metastasis 1 (ENSG00000156299), score: 0.76 TLL1tolloid-like 1 (ENSG00000038295), score: 0.91 TMBIM4transmembrane BAX inhibitor motif containing 4 (ENSG00000155957), score: -0.49 TMEM22transmembrane protein 22 (ENSG00000168917), score: 0.57 TMEM59Ltransmembrane protein 59-like (ENSG00000105696), score: 0.49 TMEM63Ctransmembrane protein 63C (ENSG00000165548), score: 0.62 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (ENSG00000185215), score: -0.6 TNFRSF1Atumor necrosis factor receptor superfamily, member 1A (ENSG00000067182), score: -0.5 TNRtenascin R (restrictin, janusin) (ENSG00000116147), score: 0.52 TNRC6Ctrinucleotide repeat containing 6C (ENSG00000078687), score: 0.46 TP73tumor protein p73 (ENSG00000078900), score: 0.53 TRIM2tripartite motif-containing 2 (ENSG00000109654), score: 0.48 TRIM3tripartite motif-containing 3 (ENSG00000110171), score: 0.59 TRIM67tripartite motif-containing 67 (ENSG00000119283), score: 0.92 TRIM9tripartite motif-containing 9 (ENSG00000100505), score: 0.53 TRPC3transient receptor potential cation channel, subfamily C, member 3 (ENSG00000138741), score: 0.73 TSPAN5tetraspanin 5 (ENSG00000168785), score: 0.48 UNC80unc-80 homolog (C. elegans) (ENSG00000144406), score: 0.62 UPF0639UPF0639 protein (ENSG00000175985), score: 0.8 VAT1Lvesicle amine transport protein 1 homolog (T. californica)-like (ENSG00000171724), score: 0.62 VSNL1visinin-like 1 (ENSG00000163032), score: 0.51 VSX1visual system homeobox 1 (ENSG00000100987), score: 0.56 WDFY3WD repeat and FYVE domain containing 3 (ENSG00000163625), score: 0.52 WHSC1L1Wolf-Hirschhorn syndrome candidate 1-like 1 (ENSG00000147548), score: 0.46 WSCD1WSC domain containing 1 (ENSG00000179314), score: 0.58 YPEL4yippee-like 4 (Drosophila) (ENSG00000166793), score: 0.54 ZFPM2zinc finger protein, multitype 2 (ENSG00000169946), score: 0.7 ZIC4Zic family member 4 (ENSG00000174963), score: 0.95 ZNF217zinc finger protein 217 (ENSG00000171940), score: -0.52 ZNF238zinc finger protein 238 (ENSG00000179456), score: 0.73 ZNF385Czinc finger protein 385C (ENSG00000187595), score: 0.54 ZNF423zinc finger protein 423 (ENSG00000102935), score: 0.51 ZNF462zinc finger protein 462 (ENSG00000148143), score: 0.49 ZNF521zinc finger protein 521 (ENSG00000198795), score: 0.84 ZNF536zinc finger protein 536 (ENSG00000198597), score: 0.6

Non-Entrez genes

Unknown, score:

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Id species tissue sex individual
gga_br_f_ca1 gga br f _
ggo_cb_m_ca1 ggo cb m _
oan_cb_m_ca1 oan cb m _
gga_cb_m_ca1 gga cb m _
oan_cb_f_ca1 oan cb f _
ptr_cb_f_ca1 ptr cb f _
mmu_cb_m1_ca1 mmu cb m 1
gga_cb_f_ca1 gga cb f _
ppa_cb_f_ca1 ppa cb f _
mmu_cb_f_ca1 mmu cb f _
ppy_cb_f_ca1 ppy cb f _
mmu_cb_m2_ca1 mmu cb m 2
mdo_cb_m_ca1 mdo cb m _
mdo_cb_f_ca1 mdo cb f _
mml_cb_f_ca1 mml cb f _
ggo_cb_f_ca1 ggo cb f _
mml_cb_m_ca1 mml cb m _
hsa_cb_f_ca1 hsa cb f _
ppa_cb_m_ca1 ppa cb m _
ptr_cb_m_ca1 ptr cb m _
hsa_cb_m_ca1 hsa cb m _

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© 2008-2010 Computational Biology Group, Department of Medical Genetics, University of Lausanne, Switzerland