Under-expression is coded with green,
over-expression with red color.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
regulation of protein amino acid phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
positive regulation of protein amino acid phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
adaptive immune response
An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).
immune effector process
Any process of the immune system that occurs as part of an immune response.
activation of immune response
Any process that initiates an immune response.
immune system process
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
leukocyte mediated immunity
Any process involved in the carrying out of an immune response by a leukocyte.
lymphocyte mediated immunity
Any process involved in the carrying out of an immune response by a lymphocyte.
humoral immune response mediated by circulating immunoglobulin
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies). An example of this is the adaptive immune response found in Mus musculus.
acute inflammatory response
Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
activation of plasma proteins involved in acute inflammatory response
Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
defense response
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
blood coagulation
The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
carbohydrate metabolic process
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
monosaccharide metabolic process
The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
glucose metabolic process
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
alcohol metabolic process
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
organic acid metabolic process
The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
pyruvate metabolic process
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
gluconeogenesis
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
oxidation reduction
The process of removal or addition of one or more electrons with or without the concomitant removal or addition of a proton or protons.
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
protein amino acid phosphorylation
The process of introducing a phosphate group on to a protein.
protein maturation by peptide bond cleavage
The hydrolysis of a peptide bond or bonds within a protein as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein.
cellular amino acid and derivative metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.
cellular amino acid metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.
glycine metabolic process
The chemical reactions and pathways involving glycine, aminoethanoic acid.
histidine metabolic process
The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
lipid metabolic process
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
fatty acid metabolic process
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
fatty acid biosynthetic process
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
steroid biosynthetic process
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
cholesterol biosynthetic process
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
steroid catabolic process
The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
cellular aromatic compound metabolic process
The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
nucleoside phosphate metabolic process
The chemical reactions and pathways involving any phosphorylated nucleoside.
phosphorus metabolic process
The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
phosphate metabolic process
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
transport
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.
lipid transport
The directed movement of lipids into, out of, within or between cells by means of some external agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
response to stress
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
inflammatory response
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
complement activation, alternative pathway
Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
complement activation, classical pathway
Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.
humoral immune response
An immune response mediated through a body fluid.
response to nutrient
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
digestion
The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
blood coagulation, extrinsic pathway
A pathway of blood coagulation in which the earlier stages of the cascade are bypassed and the activation of factor X to factor Xa is effected by the combination of factor VIIa + thromboplastin; this second pathway occurs when tissue extracts are present in optimal amounts and is much more rapid than the intrinsic pathway.
hemostasis
The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
steroid metabolic process
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
cholesterol metabolic process
The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
bile acid metabolic process
The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
negative regulation of coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.
lipid biosynthetic process
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
catabolic process
The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
biosynthetic process
The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
serine family amino acid metabolic process
The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
histidine family amino acid metabolic process
The chemical reactions and pathways involving amino acids of the histidine family.
nucleobase metabolic process
The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.
nucleotide metabolic process
The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
nucleoside monophosphate metabolic process
The chemical reactions and pathways involving a nucleoside monophosphate, a glycosamine consisting of a base linked to a deoxyribose or ribose sugar esterified with phosphate on its glycose moiety.
nucleoside monophosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a glycosamine consisting of a base linked to a deoxyribose or ribose sugar esterified with phosphate on its glycose moiety.
ribonucleoside monophosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a glycosamine consisting of a base linked to a ribose sugar esterified with phosphate on its glycose moiety.
ribonucleoside monophosphate metabolic process
The chemical reactions and pathways involving a ribonucleoside monophosphate, a glycosamine consisting of a base linked to a ribose sugar esterified with phosphate on its glycose moiety.
nucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
ribonucleotide metabolic process
The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.
ribonucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.
amine metabolic process
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
response to drug
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
response to external stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
response to wounding
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
response to endogenous stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
response to hormone stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
response to extracellular stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
response to organic substance
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
gene expression
The process by which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.
positive regulation of phosphorus metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
lipid localization
Any process by which a lipid is transported to, or maintained in, a specific location.
sterol transport
The directed movement of sterols into, out of, within or between cells by means of some external agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
lipid catabolic process
The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
carbohydrate biosynthetic process
The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
organic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.
organic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.
immunoglobulin mediated immune response
An immune response mediated by immunoglobulins, whether cell-bound or in solution.
sterol metabolic process
The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
sterol biosynthetic process
The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
phosphorylation
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
protein processing
Any protein maturation process achieved by the cleavage of peptide bonds.
drug metabolic process
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
peptidyl-tyrosine phosphorylation
The posttranslational phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
peptidyl-amino acid modification
The alteration of an amino acid residue in a peptide.
peptidyl-tyrosine modification
The modification of peptidyl-tyrosine.
organic ether metabolic process
The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds.
regulation of phosphate metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
regulation of metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
hexose metabolic process
The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
hexose biosynthetic process
The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
B cell mediated immunity
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
carboxylic acid metabolic process
The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
regulation of blood coagulation
Any process that modulates the frequency, rate or extent of blood coagulation.
positive regulation of blood coagulation
Any process that activates or increases the frequency, rate or extent of blood coagulation.
negative regulation of blood coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation.
cholesterol transport
The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of, within or between cells by means of some external agent such as a transporter or pore.
bile acid catabolic process
The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
regulation of protein modification process
Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
positive regulation of protein modification process
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
response to nutrient levels
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
regulation of response to external stimulus
Any process that modulates the frequency, rate or extent of a response to an external stimulus.
regulation of cellular protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of cellular protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
regulation of lipid transport
Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells by means of some external agent such as a transporter or pore.
negative regulation of lipid transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells by means of some external agent such as a transporter or pore.
regulation of sterol transport
Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells by means of some external agent such as a transporter or pore.
negative regulation of sterol transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells by means of some external agent such as a transporter or pore.
regulation of cholesterol transport
Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells by means of some external agent such as a transporter or pore.
negative regulation of cholesterol transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells by means of some external agent such as a transporter or pore.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
monocarboxylic acid metabolic process
The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
regulation of localization
Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
macromolecule localization
Any process by which a macromolecule is transported to, or maintained in, a specific location.
response to vitamin
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
lipoprotein particle clearance
The process by which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
chylomicron remnant clearance
The process by which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.
nucleobase, nucleoside and nucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides and nucleotides.
cellular carbohydrate biosynthetic process
The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells.
cellular nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
wound healing
The series of events that restore integrity to a damaged tissue, following an injury.
cellular ketone metabolic process
The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
response to chemical stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
regulation of phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
positive regulation of phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
fibrinolysis
An ongoing process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, resulting in the removal of small blood clots.
drug catabolic process
The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease.
exogenous drug catabolic process
The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
negative regulation of catalytic activity
Any process that stops or reduces the activity of an enzyme.
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
macromolecule modification
The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
oxoacid metabolic process
The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
post-translational protein modification
The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome.
negative regulation of molecular function
Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
cellular amine metabolic process
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
cellular lipid catabolic process
The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.
cellular catabolic process
The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
cellular biosynthetic process
The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
cellular lipid metabolic process
The chemical reactions and pathways involving lipids, as carried out by individual cells.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
cellular carbohydrate metabolic process
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
cellular nitrogen compound biosynthetic process
The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
small molecule metabolic process
The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass.
small molecule catabolic process
The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.
small molecule biosynthetic process
The chemical reactions and pathways resulting in the formation of small molecules, any monomeric molecule of small relative molecular mass.
innate immune response
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
positive regulation of phosphate metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
alcohol biosynthetic process
The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
monosaccharide biosynthetic process
The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
carboxylic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
carboxylic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
heterocycle metabolic process
The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
glycerolipid metabolic process
The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis.
glycerolipid catabolic process
The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
negative regulation of biological process
Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
response to steroid hormone stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of peptidyl-tyrosine phosphorylation
Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
positive regulation of peptidyl-tyrosine phosphorylation
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of catalytic activity
Any process that modulates the activity of an enzyme.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
coagulation
The process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
regulation of coagulation
Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
positive regulation of coagulation
Any process that activates or increases the frequency, rate or extent of coagulation.
regulation of body fluid levels
Any process that modulates the levels of body fluids.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of lipoprotein lipase activity
Any process that modulates the activity of the enzyme lipoprotein lipase.
negative regulation of lipoprotein lipase activity
Any process that stops or reduces the activity of the enzyme lipoprotein lipase.
regulation of transport
Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.
negative regulation of transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.
regulation of phosphorus metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
localization
Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
positive regulation of multicellular organismal process
Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
negative regulation of multicellular organismal process
Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
regulation of protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
positive regulation of protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
regulation of hydrolase activity
Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
negative regulation of hydrolase activity
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
protein maturation
Any process leading to the attainment of the full functional capacity of a protein.
regulation of fibrinolysis
Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
positive regulation of fibrinolysis
Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
nucleobase, nucleoside and nucleotide metabolic process
The cellular chemical reactions and pathways involving nucleobases, nucleosides and nucleotides.
regulation of lipase activity
Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
negative regulation of lipase activity
Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
regulation of macromolecule metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
regulation of wound healing
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
regulation of biological quality
Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
regulation of molecular function
Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
regulation of primary metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
regulation of response to stress
Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
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cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
positive regulation of multicellular organismal process
Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
negative regulation of multicellular organismal process
Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
regulation of metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
negative regulation of biological process
Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of localization
Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
regulation of macromolecule metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
cellular nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
cellular catabolic process
The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
cellular biosynthetic process
The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
cellular amino acid and derivative metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
regulation of primary metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
organic acid metabolic process
The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
cellular amino acid and derivative metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells.
cellular ketone metabolic process
The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
small molecule catabolic process
The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.
small molecule biosynthetic process
The chemical reactions and pathways resulting in the formation of small molecules, any monomeric molecule of small relative molecular mass.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
immune effector process
Any process of the immune system that occurs as part of an immune response.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of coagulation
Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
positive regulation of multicellular organismal process
Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
negative regulation of multicellular organismal process
Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
positive regulation of coagulation
Any process that activates or increases the frequency, rate or extent of coagulation.
negative regulation of coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
positive regulation of fibrinolysis
Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
regulation of response to stress
Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
regulation of response to external stimulus
Any process that modulates the frequency, rate or extent of a response to an external stimulus.
regulation of transport
Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.
negative regulation of transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.
regulation of body fluid levels
Any process that modulates the levels of body fluids.
regulation of catalytic activity
Any process that modulates the activity of an enzyme.
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
cellular amine metabolic process
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
cellular lipid catabolic process
The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.
organic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.
cellular carbohydrate biosynthetic process
The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells.
cellular nitrogen compound biosynthetic process
The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
organic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
regulation of protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
regulation of protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
positive regulation of protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
protein maturation
Any process leading to the attainment of the full functional capacity of a protein.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
organic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.
organic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.
positive regulation of phosphorus metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
regulation of phosphorus metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
drug catabolic process
The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease.
oxoacid metabolic process
The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
cellular lipid catabolic process
The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.
cellular carbohydrate biosynthetic process
The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells.
nucleobase metabolic process
The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.
carbohydrate biosynthetic process
The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
cellular carbohydrate metabolic process
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
nucleobase, nucleoside and nucleotide metabolic process
The cellular chemical reactions and pathways involving nucleobases, nucleosides and nucleotides.
lipid biosynthetic process
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
lipid catabolic process
The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
cellular lipid metabolic process
The chemical reactions and pathways involving lipids, as carried out by individual cells.
monosaccharide metabolic process
The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
alcohol biosynthetic process
The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
nucleobase metabolic process
The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.
nucleobase, nucleoside and nucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides and nucleotides.
positive regulation of immune response
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
activation of immune response
Any process that initiates an immune response.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
complement activation, alternative pathway
Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
negative regulation of blood coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation.
negative regulation of coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.
regulation of blood coagulation
Any process that modulates the frequency, rate or extent of blood coagulation.
positive regulation of coagulation
Any process that activates or increases the frequency, rate or extent of coagulation.
positive regulation of blood coagulation
Any process that activates or increases the frequency, rate or extent of blood coagulation.
blood coagulation
The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
negative regulation of transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.
regulation of blood coagulation
Any process that modulates the frequency, rate or extent of blood coagulation.
innate immune response
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
inflammatory response
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
response to hormone stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
lipid transport
The directed movement of lipids into, out of, within or between cells by means of some external agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
regulation of lipid transport
Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells by means of some external agent such as a transporter or pore.
negative regulation of lipid transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells by means of some external agent such as a transporter or pore.
negative regulation of catalytic activity
Any process that stops or reduces the activity of an enzyme.
cellular amino acid metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.
nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
exogenous drug catabolic process
The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
monosaccharide biosynthetic process
The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
positive regulation of cellular protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of cellular protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of phosphorus metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
negative regulation of hydrolase activity
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
regulation of cellular protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
regulation of cellular protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of cellular protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
regulation of protein modification process
Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
positive regulation of protein modification process
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
regulation of phosphate metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
positive regulation of phosphate metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
fatty acid biosynthetic process
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
glycerolipid catabolic process
The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone.
monosaccharide biosynthetic process
The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
nucleobase, nucleoside and nucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides and nucleotides.
steroid biosynthetic process
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
steroid catabolic process
The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
sterol metabolic process
The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
sterol biosynthetic process
The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
B cell mediated immunity
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
complement activation, classical pathway
Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.
positive regulation of blood coagulation
Any process that activates or increases the frequency, rate or extent of blood coagulation.
negative regulation of blood coagulation
Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation.
positive regulation of fibrinolysis
Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
negative regulation of lipid transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells by means of some external agent such as a transporter or pore.
regulation of blood coagulation
Any process that modulates the frequency, rate or extent of blood coagulation.
blood coagulation
The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
regulation of wound healing
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
response to nutrient
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
regulation of sterol transport
Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells by means of some external agent such as a transporter or pore.
negative regulation of sterol transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells by means of some external agent such as a transporter or pore.
bile acid catabolic process
The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.
fatty acid biosynthetic process
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
positive regulation of protein modification process
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
positive regulation of phosphate metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
negative regulation of lipase activity
Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
cellular amino acid metabolic process
The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents.
carboxylic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
carboxylic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
histidine metabolic process
The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
protein amino acid phosphorylation
The process of introducing a phosphate group on to a protein.
regulation of phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
positive regulation of phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
hexose biosynthetic process
The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
bile acid catabolic process
The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.
cholesterol biosynthetic process
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
nucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
regulation of fibrinolysis
Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
positive regulation of fibrinolysis
Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
negative regulation of sterol transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells by means of some external agent such as a transporter or pore.
regulation of cholesterol transport
Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells by means of some external agent such as a transporter or pore.
negative regulation of cholesterol transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells by means of some external agent such as a transporter or pore.
ribonucleoside monophosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a glycosamine consisting of a base linked to a ribose sugar esterified with phosphate on its glycose moiety.
positive regulation of protein amino acid phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
positive regulation of protein amino acid phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
regulation of protein amino acid phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
positive regulation of phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
negative regulation of lipoprotein lipase activity
Any process that stops or reduces the activity of the enzyme lipoprotein lipase.
activation of plasma proteins involved in acute inflammatory response
Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.
regulation of protein amino acid phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
positive regulation of protein amino acid phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
peptidyl-tyrosine phosphorylation
The posttranslational phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
fatty acid metabolic process
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
bile acid metabolic process
The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
gluconeogenesis
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
nucleoside monophosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a glycosamine consisting of a base linked to a deoxyribose or ribose sugar esterified with phosphate on its glycose moiety.
ribonucleoside monophosphate metabolic process
The chemical reactions and pathways involving a ribonucleoside monophosphate, a glycosamine consisting of a base linked to a ribose sugar esterified with phosphate on its glycose moiety.
ribonucleotide biosynthetic process
The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.
humoral immune response mediated by circulating immunoglobulin
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
negative regulation of cholesterol transport
Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells by means of some external agent such as a transporter or pore.
complement activation
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
positive regulation of peptidyl-tyrosine phosphorylation
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
regulation of peptidyl-tyrosine phosphorylation
Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
positive regulation of peptidyl-tyrosine phosphorylation
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
gluconeogenesis
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
ribonucleoside monophosphate biosynthetic process
The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a glycosamine consisting of a base linked to a ribose sugar esterified with phosphate on its glycose moiety.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
cell fraction
A generic term for parts of cells prepared by disruptive biochemical techniques.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
endoplasmic reticulum
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
peroxisome
A small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2).
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
membrane attack complex
A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.
extracellular space
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
membrane fraction
That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes.
insoluble fraction
That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endoplasmic reticulum membrane
The lipid bilayer surrounding the endoplasmic reticulum.
microsome
Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic cells are homogenized and that sediment on centrifugation at 100000 g.
endomembrane system
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
pore complex
Any small opening in a membrane that allows the passage of gases and/or liquids.
organelle membrane
The lipid bilayer surrounding an organelle.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
protein-lipid complex
A macromolecular complex containing both protein and lipid molecules.
plasma lipoprotein particle
A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.
very-low-density lipoprotein particle
A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.
high-density lipoprotein particle
A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.
triglyceride-rich lipoprotein particle
A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoproteinparticles transport lipids, which are non-covalently associated with the particles, in the blood.
nuclear membrane-endoplasmic reticulum network
The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.
microbody
Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).
vesicular fraction
Any of the small, heterogeneous, artifactual, vesicular particles that are formed when some cells are homogenized.
chylomicron
A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
subsynaptic reticulum
An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.
all
NA
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
plasma lipoprotein particle
A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.
organelle membrane
The lipid bilayer surrounding an organelle.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
plasma lipoprotein particle
A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
organelle membrane
The lipid bilayer surrounding an organelle.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
nuclear membrane-endoplasmic reticulum network
The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
endoplasmic reticulum membrane
The lipid bilayer surrounding the endoplasmic reticulum.
nuclear membrane-endoplasmic reticulum network
The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum.
endoplasmic reticulum membrane
The lipid bilayer surrounding the endoplasmic reticulum.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
endoplasmic reticulum membrane
The lipid bilayer surrounding the endoplasmic reticulum.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endoplasmic reticulum
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
microbody
Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
subsynaptic reticulum
An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.
membrane attack complex
A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
endoplasmic reticulum part
Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
pore complex
Any small opening in a membrane that allows the passage of gases and/or liquids.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
membrane attack complex
A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
enzyme inhibitor activity
Stops, prevents or reduces the activity of an enzyme.
endopeptidase inhibitor activity
Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
serine-type endopeptidase inhibitor activity
Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.
carbohydrate binding
Interacting selectively and non-covalently with any carbohydrate, any of a group of organic compounds based of the general formula Cx(H2O)y.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
transmembrane transporter activity
Enables the transfer of a substance from one side of a membrane to the other.
organic acid transmembrane transporter activity
Catalysis of the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other.
binding
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
steroid binding
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
lipid binding
Interacting selectively and non-covalently with a lipid.
anion transmembrane transporter activity
Catalysis of the transfer of a negatively charged ion from one side of a membrane to the other.
organic anion transmembrane transporter activity
Catalysis of the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
endopeptidase regulator activity
Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
ion transmembrane transporter activity
Catalysis of the transfer of an ion from one side of a membrane to the other.
amino acid binding
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
oxidoreductase activity, acting on CH-OH group of donors
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
peptidase inhibitor activity
Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
vitamin binding
Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
active transmembrane transporter activity
Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific transporter activity
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
pyridoxal phosphate binding
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
enzyme regulator activity
Modulates the activity of an enzyme.
carboxylic acid binding
Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
amine binding
Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group.
carboxylic acid transmembrane transporter activity
Catalysis of the transfer of carboxylic acids from one side of the membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
cofactor binding
Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
peptidase regulator activity
Modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
vitamin B6 binding
Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
all
NA
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
amino acid binding
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
peptidase inhibitor activity
Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
pyridoxal phosphate binding
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
endopeptidase inhibitor activity
Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 04610 | 2.513e-10 | 1.955 | 17 | 50 | Complement and coagulation cascades |
| 01100 | 4.652e-05 | 31.48 | 57 | 805 | Metabolic pathways |
| 00983 | 8.791e-04 | 0.9385 | 7 | 24 | Drug metabolism - other enzymes |
| 01040 | 5.150e-03 | 0.5865 | 5 | 15 | Biosynthesis of unsaturated fatty acids |
| 04146 | 6.028e-03 | 2.62 | 10 | 67 | Peroxisome |
| 00232 | 6.082e-03 | 0.1564 | 3 | 4 | Caffeine metabolism |
| 00260 | 6.386e-03 | 0.9385 | 6 | 24 | Glycine, serine and threonine metabolism |
| 00830 | 7.759e-03 | 0.9776 | 6 | 25 | Retinol metabolism |
| 00120 | 9.417e-03 | 0.391 | 4 | 10 | Primary bile acid biosynthesis |
| 00340 | 3.528e-02 | 0.9385 | 5 | 24 | Histidine metabolism |
| 04950 | 3.818e-02 | 0.5865 | 4 | 15 | Maturity onset diabetes of the young |
| 03320 | 4.871e-02 | 1.955 | 7 | 50 | PPAR signaling pathway |
A1CFAPOBEC1 complementation factor (ENSG00000148584), score: 0.57 ABCC3ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (ENSG00000108846), score: 0.55 ABCG5ATP-binding cassette, sub-family G (WHITE), member 5 (ENSG00000138075), score: 0.63 ACOX3acyl-CoA oxidase 3, pristanoyl (ENSG00000087008), score: 0.59 ACSM5acyl-CoA synthetase medium-chain family member 5 (ENSG00000183549), score: 0.53 ADH4alcohol dehydrogenase 4 (class II), pi polypeptide (ENSG00000198099), score: 0.64 ADIPOR2adiponectin receptor 2 (ENSG00000006831), score: 0.69 ADKadenosine kinase (ENSG00000156110), score: 0.61 ADRA1Aadrenergic, alpha-1A-, receptor (ENSG00000120907), score: 0.56 AGFG2ArfGAP with FG repeats 2 (ENSG00000106351), score: 0.56 AGXTalanine-glyoxylate aminotransferase (ENSG00000172482), score: 0.58 AKR1D1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (ENSG00000122787), score: 0.61 ALBalbumin (ENSG00000163631), score: 0.58 ALDH2aldehyde dehydrogenase 2 family (mitochondrial) (ENSG00000111275), score: 0.57 AMBPalpha-1-microglobulin/bikunin precursor (ENSG00000106927), score: 0.6 AMDHD1amidohydrolase domain containing 1 (ENSG00000139344), score: 0.54 ANO1anoctamin 1, calcium activated chloride channel (ENSG00000131620), score: 0.54 APCSamyloid P component, serum (ENSG00000132703), score: 0.57 APOBapolipoprotein B (including Ag(x) antigen) (ENSG00000084674), score: 0.58 APOC1apolipoprotein C-I (ENSG00000130208), score: 0.66 APOC3apolipoprotein C-III (ENSG00000110245), score: 0.62 APOFapolipoprotein F (ENSG00000175336), score: 0.62 AQP9aquaporin 9 (ENSG00000103569), score: 0.63 ARG1arginase, liver (ENSG00000118520), score: 0.62 ARHGEF2Rho/Rac guanine nucleotide exchange factor (GEF) 2 (ENSG00000116584), score: -0.59 ARHGEF3Rho guanine nucleotide exchange factor (GEF) 3 (ENSG00000163947), score: -0.56 ARID3CAT rich interactive domain 3C (BRIGHT-like) (ENSG00000205143), score: 0.77 ARMC5armadillo repeat containing 5 (ENSG00000140691), score: 0.61 ARMC6armadillo repeat containing 6 (ENSG00000105676), score: 0.56 ARSEarylsulfatase E (chondrodysplasia punctata 1) (ENSG00000157399), score: 0.64 ASPGasparaginase homolog (S. cerevisiae) (ENSG00000166183), score: 0.6 BAATbile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) (ENSG00000136881), score: 0.57 BCHEbutyrylcholinesterase (ENSG00000114200), score: 0.62 C10orf140chromosome 10 open reading frame 140 (ENSG00000180592), score: 0.55 C10orf47chromosome 10 open reading frame 47 (ENSG00000148426), score: 0.54 C10orf58chromosome 10 open reading frame 58 (ENSG00000122378), score: 0.57 C13orf15chromosome 13 open reading frame 15 (ENSG00000102760), score: -0.66 C14orf1chromosome 14 open reading frame 1 (ENSG00000133935), score: 0.6 C14orf104chromosome 14 open reading frame 104 (ENSG00000165506), score: 0.57 C14orf182chromosome 14 open reading frame 182 (ENSG00000214900), score: 0.56 C14orf21chromosome 14 open reading frame 21 (ENSG00000196943), score: 0.72 C1orf43chromosome 1 open reading frame 43 (ENSG00000143612), score: 0.56 C1orf53chromosome 1 open reading frame 53 (ENSG00000203724), score: 0.55 C20orf194chromosome 20 open reading frame 194 (ENSG00000088854), score: -0.62 C4BPAcomplement component 4 binding protein, alpha (ENSG00000123838), score: 0.56 C4BPBcomplement component 4 binding protein, beta (ENSG00000123843), score: 0.57 C5complement component 5 (ENSG00000106804), score: 0.53 C5orf33chromosome 5 open reading frame 33 (ENSG00000152620), score: 0.64 C5orf43chromosome 5 open reading frame 43 (ENSG00000188725), score: 0.54 C8Acomplement component 8, alpha polypeptide (ENSG00000157131), score: 0.61 C8Bcomplement component 8, beta polypeptide (ENSG00000021852), score: 0.6 C8Gcomplement component 8, gamma polypeptide (ENSG00000176919), score: 0.53 CARScysteinyl-tRNA synthetase (ENSG00000110619), score: 0.54 CD4CD4 molecule (ENSG00000010610), score: 0.59 CD40LGCD40 ligand (ENSG00000102245), score: 0.55 CD7CD7 molecule (ENSG00000173762), score: 0.61 CD81CD81 molecule (ENSG00000110651), score: 0.54 CDAcytidine deaminase (ENSG00000158825), score: 0.53 CES7carboxylesterase 7 (ENSG00000159398), score: 0.55 CHST10carbohydrate sulfotransferase 10 (ENSG00000115526), score: -0.59 CHST13carbohydrate (chondroitin 4) sulfotransferase 13 (ENSG00000180767), score: 0.6 CIB2calcium and integrin binding family member 2 (ENSG00000136425), score: -0.56 CIDEBcell death-inducing DFFA-like effector b (ENSG00000136305), score: 0.6 CLDN1claudin 1 (ENSG00000163347), score: 0.56 CLDN14claudin 14 (ENSG00000159261), score: 0.59 CLEC1BC-type lectin domain family 1, member B (ENSG00000165682), score: 0.64 CMTM8CKLF-like MARVEL transmembrane domain containing 8 (ENSG00000170293), score: 0.61 CNGA1cyclic nucleotide gated channel alpha 1 (ENSG00000198515), score: 0.63 COLEC10collectin sub-family member 10 (C-type lectin) (ENSG00000184374), score: 0.54 CPB2carboxypeptidase B2 (plasma) (ENSG00000080618), score: 0.61 CPN2carboxypeptidase N, polypeptide 2 (ENSG00000178772), score: 0.56 CREB3L3cAMP responsive element binding protein 3-like 3 (ENSG00000060566), score: 0.54 CSADcysteine sulfinic acid decarboxylase (ENSG00000139631), score: 0.55 CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 2 (ENSG00000140505), score: 0.74 CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 8 (ENSG00000138115), score: 0.61 CYP39A1cytochrome P450, family 39, subfamily A, polypeptide 1 (ENSG00000146233), score: 0.58 DACT2dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis) (ENSG00000164488), score: 0.58 DAKdihydroxyacetone kinase 2 homolog (S. cerevisiae) (ENSG00000149476), score: 0.59 DCXRdicarbonyl/L-xylulose reductase (ENSG00000169738), score: 0.6 DDI2DNA-damage inducible 1 homolog 2 (S. cerevisiae) (ENSG00000197312), score: 0.67 DERL1Der1-like domain family, member 1 (ENSG00000136986), score: 0.54 DGAT2diacylglycerol O-acyltransferase 2 (ENSG00000062282), score: 0.56 DHCR77-dehydrocholesterol reductase (ENSG00000172893), score: 0.58 DHRS2dehydrogenase/reductase (SDR family) member 2 (ENSG00000100867), score: 0.78 DHTKD1dehydrogenase E1 and transketolase domain containing 1 (ENSG00000181192), score: 0.59 DNAJC22DnaJ (Hsp40) homolog, subfamily C, member 22 (ENSG00000178401), score: 0.56 DPYDdihydropyrimidine dehydrogenase (ENSG00000188641), score: 0.53 DSG1desmoglein 1 (ENSG00000134760), score: 0.65 EI24etoposide induced 2.4 mRNA (ENSG00000149547), score: 0.79 ELOVL6ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) (ENSG00000170522), score: 0.59 ENDOD1endonuclease domain containing 1 (ENSG00000149218), score: -0.56 EPHX1epoxide hydrolase 1, microsomal (xenobiotic) (ENSG00000143819), score: 0.6 ERGIC1endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 (ENSG00000113719), score: 0.6 ERP29endoplasmic reticulum protein 29 (ENSG00000089248), score: 0.56 ESR1estrogen receptor 1 (ENSG00000091831), score: 0.6 F10coagulation factor X (ENSG00000126218), score: 0.54 F11coagulation factor XI (ENSG00000088926), score: 0.57 F12coagulation factor XII (Hageman factor) (ENSG00000131187), score: 0.55 F2coagulation factor II (thrombin) (ENSG00000180210), score: 0.59 F7coagulation factor VII (serum prothrombin conversion accelerator) (ENSG00000057593), score: 0.6 F9coagulation factor IX (ENSG00000101981), score: 0.62 FADS2fatty acid desaturase 2 (ENSG00000134824), score: 0.56 FAM26Ffamily with sequence similarity 26, member F (ENSG00000188820), score: 0.53 FAM96Afamily with sequence similarity 96, member A (ENSG00000166797), score: 0.55 FAR1fatty acyl CoA reductase 1 (ENSG00000197601), score: -0.58 FASLGFas ligand (TNF superfamily, member 6) (ENSG00000117560), score: 0.55 FASNfatty acid synthase (ENSG00000169710), score: 0.53 FBXL4F-box and leucine-rich repeat protein 4 (ENSG00000112234), score: 0.53 FCER1AFc fragment of IgE, high affinity I, receptor for; alpha polypeptide (ENSG00000179639), score: 0.69 FETUBfetuin B (ENSG00000090512), score: 0.62 FGF21fibroblast growth factor 21 (ENSG00000105550), score: 0.53 FKBP2FK506 binding protein 2, 13kDa (ENSG00000173486), score: 0.58 FMO3flavin containing monooxygenase 3 (ENSG00000007933), score: 0.56 FMO5flavin containing monooxygenase 5 (ENSG00000131781), score: 0.56 FOXA1forkhead box A1 (ENSG00000129514), score: 0.62 FOXA3forkhead box A3 (ENSG00000170608), score: 0.61 FRRS1ferric-chelate reductase 1 (ENSG00000156869), score: 0.59 FTCDformiminotransferase cyclodeaminase (ENSG00000160282), score: 0.59 FUBP3far upstream element (FUSE) binding protein 3 (ENSG00000107164), score: 0.54 FURINfurin (paired basic amino acid cleaving enzyme) (ENSG00000140564), score: 0.55 GAL3ST2galactose-3-O-sulfotransferase 2 (ENSG00000154252), score: 0.75 GALTgalactose-1-phosphate uridylyltransferase (ENSG00000213930), score: 0.55 GAMTguanidinoacetate N-methyltransferase (ENSG00000130005), score: 0.58 GANABglucosidase, alpha; neutral AB (ENSG00000089597), score: 0.58 GCgroup-specific component (vitamin D binding protein) (ENSG00000145321), score: 0.57 GCKglucokinase (hexokinase 4) (ENSG00000106633), score: 0.6 GCKRglucokinase (hexokinase 4) regulator (ENSG00000084734), score: 0.61 GDF2growth differentiation factor 2 (ENSG00000128802), score: 0.57 GDF7growth differentiation factor 7 (ENSG00000143869), score: 0.6 GHRgrowth hormone receptor (ENSG00000112964), score: 0.57 GNEglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (ENSG00000159921), score: 0.59 GNMTglycine N-methyltransferase (ENSG00000124713), score: 0.55 GNPNAT1glucosamine-phosphate N-acetyltransferase 1 (ENSG00000100522), score: 0.63 GPAMglycerol-3-phosphate acyltransferase, mitochondrial (ENSG00000119927), score: 0.65 GPD2glycerol-3-phosphate dehydrogenase 2 (mitochondrial) (ENSG00000115159), score: -0.57 GPR128G protein-coupled receptor 128 (ENSG00000144820), score: 0.53 GPRC5BG protein-coupled receptor, family C, group 5, member B (ENSG00000167191), score: -0.63 GPT2glutamic pyruvate transaminase (alanine aminotransferase) 2 (ENSG00000166123), score: 0.57 GUCA2Bguanylate cyclase activator 2B (uroguanylin) (ENSG00000044012), score: 0.73 GYS2glycogen synthase 2 (liver) (ENSG00000111713), score: 0.65 HAO1hydroxyacid oxidase (glycolate oxidase) 1 (ENSG00000101323), score: 0.68 HMGCS23-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (ENSG00000134240), score: 0.56 HOMER2homer homolog 2 (Drosophila) (ENSG00000103942), score: 0.53 HPXhemopexin (ENSG00000110169), score: 0.56 HRGhistidine-rich glycoprotein (ENSG00000113905), score: 0.55 HSD11B1hydroxysteroid (11-beta) dehydrogenase 1 (ENSG00000117594), score: 0.59 HSD17B13hydroxysteroid (17-beta) dehydrogenase 13 (ENSG00000170509), score: 0.72 HSPA12Aheat shock 70kDa protein 12A (ENSG00000165868), score: -0.57 IGF1Rinsulin-like growth factor 1 receptor (ENSG00000140443), score: -0.62 IGFALSinsulin-like growth factor binding protein, acid labile subunit (ENSG00000099769), score: 0.68 IL17RCinterleukin 17 receptor C (ENSG00000163702), score: 0.57 IL17REinterleukin 17 receptor E (ENSG00000163701), score: 0.7 IL22RA1interleukin 22 receptor, alpha 1 (ENSG00000142677), score: 0.6 IL2RBinterleukin 2 receptor, beta (ENSG00000100385), score: 0.59 IL6Rinterleukin 6 receptor (ENSG00000160712), score: 0.58 IMPDH1IMP (inosine 5'-monophosphate) dehydrogenase 1 (ENSG00000106348), score: -0.61 INHBCinhibin, beta C (ENSG00000175189), score: 0.66 INHBEinhibin, beta E (ENSG00000139269), score: 0.72 INSIG1insulin induced gene 1 (ENSG00000186480), score: 0.55 IQCKIQ motif containing K (ENSG00000174628), score: -0.56 ITIH1inter-alpha (globulin) inhibitor H1 (ENSG00000055957), score: 0.61 ITIH4inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) (ENSG00000055955), score: 0.57 JAGN1jagunal homolog 1 (Drosophila) (ENSG00000171135), score: 0.58 JMJD5jumonji domain containing 5 (ENSG00000155666), score: 0.79 KCTD3potassium channel tetramerisation domain containing 3 (ENSG00000136636), score: 0.54 KIAA0922KIAA0922 (ENSG00000121210), score: 0.54 KIAA1161KIAA1161 (ENSG00000164976), score: 0.53 KLBklotho beta (ENSG00000134962), score: 0.56 KLKB1kallikrein B, plasma (Fletcher factor) 1 (ENSG00000164344), score: 0.6 KRTCAP3keratinocyte associated protein 3 (ENSG00000157992), score: 0.55 LASS2LAG1 homolog, ceramide synthase 2 (ENSG00000143418), score: 0.58 LCMT1leucine carboxyl methyltransferase 1 (ENSG00000205629), score: -0.57 LECT2leukocyte cell-derived chemotaxin 2 (ENSG00000145826), score: 0.66 LEPRleptin receptor (ENSG00000116678), score: 0.57 LGSNlengsin, lens protein with glutamine synthetase domain (ENSG00000146166), score: 0.67 LIPClipase, hepatic (ENSG00000166035), score: 0.76 LOC55908hepatocellular carcinoma-associated gene TD26 (ENSG00000130173), score: 0.61 LRP12low density lipoprotein receptor-related protein 12 (ENSG00000147650), score: -0.57 LRRC3leucine rich repeat containing 3 (ENSG00000160233), score: 0.65 LRRC31leucine rich repeat containing 31 (ENSG00000114248), score: 0.84 LSRlipolysis stimulated lipoprotein receptor (ENSG00000105699), score: 0.57 LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (ENSG00000160285), score: 0.59 LY6Elymphocyte antigen 6 complex, locus E (ENSG00000160932), score: 0.54 LYPD2LY6/PLAUR domain containing 2 (ENSG00000197353), score: 0.9 MAP2K6mitogen-activated protein kinase kinase 6 (ENSG00000108984), score: 0.59 MAT1Amethionine adenosyltransferase I, alpha (ENSG00000151224), score: 0.56 MBNL3muscleblind-like 3 (Drosophila) (ENSG00000076770), score: 0.57 MGMTO-6-methylguanine-DNA methyltransferase (ENSG00000170430), score: 0.54 MINPP1multiple inositol-polyphosphate phosphatase 1 (ENSG00000107789), score: 0.69 MMABmethylmalonic aciduria (cobalamin deficiency) cblB type (ENSG00000139428), score: 0.56 MOGAT1monoacylglycerol O-acyltransferase 1 (ENSG00000124003), score: 0.63 MOSC1MOCO sulphurase C-terminal domain containing 1 (ENSG00000186205), score: 0.56 MPGN-methylpurine-DNA glycosylase (ENSG00000103152), score: 0.55 MRASmuscle RAS oncogene homolog (ENSG00000158186), score: -0.57 MTTPmicrosomal triglyceride transfer protein (ENSG00000138823), score: 0.56 MUTmethylmalonyl CoA mutase (ENSG00000146085), score: 0.54 MVKmevalonate kinase (ENSG00000110921), score: 0.55 NAT2N-acetyltransferase 2 (arylamine N-acetyltransferase) (ENSG00000156006), score: 0.7 NFATC2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (ENSG00000101096), score: 0.74 NIPAL1NIPA-like domain containing 1 (ENSG00000163293), score: 0.57 NPC1L1NPC1 (Niemann-Pick disease, type C1, gene)-like 1 (ENSG00000015520), score: 0.72 NPWneuropeptide W (ENSG00000183971), score: 0.68 NR1I2nuclear receptor subfamily 1, group I, member 2 (ENSG00000144852), score: 0.62 NSUN2NOP2/Sun domain family, member 2 (ENSG00000037474), score: 0.56 NUDT5nudix (nucleoside diphosphate linked moiety X)-type motif 5 (ENSG00000165609), score: 0.54 ONECUT2one cut homeobox 2 (ENSG00000119547), score: 0.65 ORM1orosomucoid 1 (ENSG00000229314), score: 0.54 ORMDL3ORM1-like 3 (S. cerevisiae) (ENSG00000172057), score: 0.54 OTCornithine carbamoyltransferase (ENSG00000036473), score: 0.62 OXCT13-oxoacid CoA transferase 1 (ENSG00000083720), score: -0.6 OXER1oxoeicosanoid (OXE) receptor 1 (ENSG00000162881), score: 0.67 PAICSphosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (ENSG00000128050), score: 0.6 PDE6Gphosphodiesterase 6G, cGMP-specific, rod, gamma (ENSG00000185527), score: 0.58 PEMTphosphatidylethanolamine N-methyltransferase (ENSG00000133027), score: 0.57 PEX11Aperoxisomal biogenesis factor 11 alpha (ENSG00000166821), score: 0.65 PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (ENSG00000158571), score: 0.61 PGAM5phosphoglycerate mutase family member 5 (ENSG00000176894), score: 0.69 PGLYRP2peptidoglycan recognition protein 2 (ENSG00000161031), score: 0.68 PKLRpyruvate kinase, liver and RBC (ENSG00000143627), score: 0.64 PLA2G12Bphospholipase A2, group XIIB (ENSG00000138308), score: 0.56 PNMA1paraneoplastic antigen MA1 (ENSG00000176903), score: -0.61 POFUT1protein O-fucosyltransferase 1 (ENSG00000101346), score: 0.58 PON1paraoxonase 1 (ENSG00000005421), score: 0.6 PON3paraoxonase 3 (ENSG00000105852), score: 0.58 PORP450 (cytochrome) oxidoreductase (ENSG00000127948), score: 0.56 PPP1R15Bprotein phosphatase 1, regulatory (inhibitor) subunit 15B (ENSG00000158615), score: 0.53 PRG2proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) (ENSG00000186652), score: 0.77 PRG4proteoglycan 4 (ENSG00000116690), score: 0.58 PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit (ENSG00000131791), score: 0.54 PROCprotein C (inactivator of coagulation factors Va and VIIIa) (ENSG00000115718), score: 0.57 PRRG4proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) (ENSG00000135378), score: 0.66 PTMSparathymosin (ENSG00000159335), score: 0.56 PYGLphosphorylase, glycogen, liver (ENSG00000100504), score: 0.54 RAB8ARAB8A, member RAS oncogene family (ENSG00000167461), score: 0.6 RAD23BRAD23 homolog B (S. cerevisiae) (ENSG00000119318), score: 0.56 RALGAPA2Ral GTPase activating protein, alpha subunit 2 (catalytic) (ENSG00000188559), score: 0.59 RARRES2retinoic acid receptor responder (tazarotene induced) 2 (ENSG00000106538), score: 0.56 RBP4retinol binding protein 4, plasma (ENSG00000138207), score: 0.55 RDH16retinol dehydrogenase 16 (all-trans) (ENSG00000139547), score: 0.62 RDH5retinol dehydrogenase 5 (11-cis/9-cis) (ENSG00000135437), score: 0.53 RFNGRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (ENSG00000169733), score: 0.59 RIPPLY1ripply1 homolog (zebrafish) (ENSG00000147223), score: 0.53 RTP3receptor (chemosensory) transporter protein 3 (ENSG00000163825), score: 0.59 RXRAretinoid X receptor, alpha (ENSG00000186350), score: 0.58 SARDHsarcosine dehydrogenase (ENSG00000123453), score: 0.53 SCDstearoyl-CoA desaturase (delta-9-desaturase) (ENSG00000099194), score: 0.55 SCP2sterol carrier protein 2 (ENSG00000116171), score: 0.56 SDSserine dehydratase (ENSG00000135094), score: 0.56 SEBOXSEBOX homeobox (ENSG00000109072), score: 0.53 SEC14L4SEC14-like 4 (S. cerevisiae) (ENSG00000133488), score: 0.64 SERPINA10serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 (ENSG00000140093), score: 0.59 SERPINA11serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 (ENSG00000186910), score: 0.61 SERPINA4serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 (ENSG00000100665), score: 0.69 SERPINA7serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (ENSG00000123561), score: 0.55 SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 1 (ENSG00000117601), score: 0.59 SERPIND1serpin peptidase inhibitor, clade D (heparin cofactor), member 1 (ENSG00000099937), score: 0.59 SFT2D3SFT2 domain containing 3 (ENSG00000173349), score: 0.55 SGCBsarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (ENSG00000163069), score: -0.72 SHHsonic hedgehog (ENSG00000164690), score: 0.91 SHMT2serine hydroxymethyltransferase 2 (mitochondrial) (ENSG00000182199), score: 0.58 SIGMAR1sigma non-opioid intracellular receptor 1 (ENSG00000147955), score: 0.63 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (ENSG00000100652), score: 0.63 SLC13A5solute carrier family 13 (sodium-dependent citrate transporter), member 5 (ENSG00000141485), score: 0.64 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (ENSG00000088386), score: 0.59 SLC16A11solute carrier family 16, member 11 (monocarboxylic acid transporter 11) (ENSG00000174326), score: 0.65 SLC16A13solute carrier family 16, member 13 (monocarboxylic acid transporter 13) (ENSG00000174327), score: 0.59 SLC16A2solute carrier family 16, member 2 (monocarboxylic acid transporter 8) (ENSG00000147100), score: 0.56 SLC17A2solute carrier family 17 (sodium phosphate), member 2 (ENSG00000112337), score: 0.61 SLC17A4solute carrier family 17 (sodium phosphate), member 4 (ENSG00000146039), score: 0.54 SLC17A9solute carrier family 17, member 9 (ENSG00000101194), score: 0.64 SLC19A1solute carrier family 19 (folate transporter), member 1 (ENSG00000173638), score: 0.56 SLC22A1solute carrier family 22 (organic cation transporter), member 1 (ENSG00000175003), score: 0.62 SLC22A3solute carrier family 22 (extraneuronal monoamine transporter), member 3 (ENSG00000146477), score: 0.64 SLC25A13solute carrier family 25, member 13 (citrin) (ENSG00000004864), score: 0.53 SLC25A15solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 (ENSG00000102743), score: 0.62 SLC25A16solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 (ENSG00000122912), score: 0.54 SLC25A36solute carrier family 25, member 36 (ENSG00000114120), score: -0.64 SLC25A47solute carrier family 25, member 47 (ENSG00000140107), score: 0.68 SLC2A2solute carrier family 2 (facilitated glucose transporter), member 2 (ENSG00000163581), score: 0.61 SLC35D1solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 (ENSG00000116704), score: 0.6 SLC38A4solute carrier family 38, member 4 (ENSG00000139209), score: 0.6 SLC39A8solute carrier family 39 (zinc transporter), member 8 (ENSG00000138821), score: 0.54 SLC41A2solute carrier family 41, member 2 (ENSG00000136052), score: 0.54 SLC43A1solute carrier family 43, member 1 (ENSG00000149150), score: 0.62 SLC43A3solute carrier family 43, member 3 (ENSG00000134802), score: 0.55 SLC7A2solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 (ENSG00000003989), score: 0.59 SLCO1B1solute carrier organic anion transporter family, member 1B1 (ENSG00000134538), score: 0.59 SLCO1B3solute carrier organic anion transporter family, member 1B3 (ENSG00000111700), score: 0.67 SLCO2B1solute carrier organic anion transporter family, member 2B1 (ENSG00000137491), score: 0.67 SORT1sortilin 1 (ENSG00000134243), score: -0.63 SP5Sp5 transcription factor (ENSG00000204335), score: 0.57 SPG21spastic paraplegia 21 (autosomal recessive, Mast syndrome) (ENSG00000090487), score: 0.57 SPP2secreted phosphoprotein 2, 24kDa (ENSG00000072080), score: 0.66 SPRYD4SPRY domain containing 4 (ENSG00000176422), score: 0.54 SRD5A2steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (ENSG00000049319), score: 0.9 SSBP2single-stranded DNA binding protein 2 (ENSG00000145687), score: -0.6 ST13suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) (ENSG00000100380), score: 0.57 STAU1staufen, RNA binding protein, homolog 1 (Drosophila) (ENSG00000124214), score: 0.54 STK39serine threonine kinase 39 (ENSG00000198648), score: -0.67 SULT2A1sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (ENSG00000105398), score: 0.57 SYVN1synovial apoptosis inhibitor 1, synoviolin (ENSG00000162298), score: 0.54 TAAR5trace amine associated receptor 5 (ENSG00000135569), score: 0.6 TATtyrosine aminotransferase (ENSG00000198650), score: 0.54 TBC1D22BTBC1 domain family, member 22B (ENSG00000065491), score: -0.57 TBX15T-box 15 (ENSG00000092607), score: 0.78 TCF7transcription factor 7 (T-cell specific, HMG-box) (ENSG00000081059), score: 0.53 TCTN2tectonic family member 2 (ENSG00000168778), score: -0.56 TDGF1teratocarcinoma-derived growth factor 1 (ENSG00000241186), score: 0.54 TFF2trefoil factor 2 (ENSG00000160181), score: 0.69 TFR2transferrin receptor 2 (ENSG00000106327), score: 0.58 TH1LTH1-like (Drosophila) (ENSG00000101158), score: 0.56 THRSPthyroid hormone responsive (ENSG00000151365), score: 0.66 TM4SF4transmembrane 4 L six family member 4 (ENSG00000169903), score: 0.62 TM6SF2transmembrane 6 superfamily member 2 (ENSG00000213996), score: 0.54 TMBIM6transmembrane BAX inhibitor motif containing 6 (ENSG00000139644), score: 0.54 TMED2transmembrane emp24 domain trafficking protein 2 (ENSG00000086598), score: 0.54 TMEM135transmembrane protein 135 (ENSG00000166575), score: 0.59 TMEM195transmembrane protein 195 (ENSG00000187546), score: 0.71 TMEM231transmembrane protein 231 (ENSG00000205084), score: -0.58 TMEM86Btransmembrane protein 86B (ENSG00000180089), score: 0.56 TMEM97transmembrane protein 97 (ENSG00000109084), score: 0.55 TMUB1transmembrane and ubiquitin-like domain containing 1 (ENSG00000164897), score: 0.54 TOR3Atorsin family 3, member A (ENSG00000186283), score: 0.55 TP53BP1tumor protein p53 binding protein 1 (ENSG00000067369), score: -0.63 TPST2tyrosylprotein sulfotransferase 2 (ENSG00000128294), score: 0.56 TRIB3tribbles homolog 3 (Drosophila) (ENSG00000101255), score: 0.6 TRPM8transient receptor potential cation channel, subfamily M, member 8 (ENSG00000144481), score: 0.84 TTC39Ctetratricopeptide repeat domain 39C (ENSG00000168234), score: 0.6 TTLL1tubulin tyrosine ligase-like family, member 1 (ENSG00000100271), score: -0.6 TTPAtocopherol (alpha) transfer protein (ENSG00000137561), score: 0.59 TTPALtocopherol (alpha) transfer protein-like (ENSG00000124120), score: 0.62 TTRtransthyretin (ENSG00000118271), score: 0.6 TUSC3tumor suppressor candidate 3 (ENSG00000104723), score: -0.62 TXNL4Bthioredoxin-like 4B (ENSG00000140830), score: 0.53 TXNRD2thioredoxin reductase 2 (ENSG00000184470), score: 0.55 UGP2UDP-glucose pyrophosphorylase 2 (ENSG00000169764), score: 0.62 UMPSuridine monophosphate synthetase (ENSG00000114491), score: 0.53 UNC93Aunc-93 homolog A (C. elegans) (ENSG00000112494), score: 0.58 UROC1urocanase domain containing 1 (ENSG00000159650), score: 0.71 USH2AUsher syndrome 2A (autosomal recessive, mild) (ENSG00000042781), score: 1 VWCEvon Willebrand factor C and EGF domains (ENSG00000167992), score: 0.62 XBP1X-box binding protein 1 (ENSG00000100219), score: 0.54 XDHxanthine dehydrogenase (ENSG00000158125), score: 0.55 ZBED1zinc finger, BED-type containing 1 (ENSG00000214717), score: 0.54 ZG16zymogen granule protein 16 homolog (rat) (ENSG00000174992), score: 1 ZGPATzinc finger, CCCH-type with G patch domain (ENSG00000197114), score: 0.72 ZNF135zinc finger protein 135 (ENSG00000176293), score: -0.57 ZNF462zinc finger protein 462 (ENSG00000148143), score: -0.55 ZNF511zinc finger protein 511 (ENSG00000198546), score: 0.67 ZNF648zinc finger protein 648 (ENSG00000179930), score: 0.63 ZNF827zinc finger protein 827 (ENSG00000151612), score: -0.56
| Id | species | tissue | sex | individual |
|---|---|---|---|---|
| ptr_lv_m_ca1 | ptr | lv | m | _ |
| hsa_lv_m2_ca1 | hsa | lv | m | 2 |
| hsa_lv_m1_ca1 | hsa | lv | m | 1 |
