Under-expression is coded with green,
over-expression with red color.
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
cell surface receptor linked signaling pathway
Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.
enzyme linked receptor protein signaling pathway
Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase.
transmembrane receptor protein tyrosine kinase signaling pathway
The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.
cell-cell signaling
Any process that mediates the transfer of information from one cell to another.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
anatomical structure morphogenesis
The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
nervous system development
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
central nervous system development
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
brain development
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
fibroblast growth factor receptor signaling pathway
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
neurogenesis
Generation of cells within the nervous system.
signaling pathway
The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms.
signaling
The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.
cell differentiation
The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
neuron differentiation
The process whereby a relatively unspecialized cell acquires specialized features of a neuron.
midbrain development
The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
generation of neurons
The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
all
NA
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
cell-cell signaling
Any process that mediates the transfer of information from one cell to another.
anatomical structure morphogenesis
The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
central nervous system development
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
neurogenesis
Generation of cells within the nervous system.
brain development
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
midbrain development
The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).
neuron differentiation
The process whereby a relatively unspecialized cell acquires specialized features of a neuron.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
nucleic acid binding
Interacting selectively and non-covalently with any nucleic acid.
DNA binding
Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).
sequence-specific DNA binding transcription factor activity
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
binding
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
sequence-specific DNA binding
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
all
NA
ANKLE1ankyrin repeat and LEM domain containing 1 (ENSG00000160117), score: 0.75 BARHL1BarH-like homeobox 1 (ENSG00000125492), score: 0.77 BARHL2BarH-like homeobox 2 (ENSG00000143032), score: 0.81 C16orf11chromosome 16 open reading frame 11 (ENSG00000161992), score: 0.73 C1orf127chromosome 1 open reading frame 127 (ENSG00000175262), score: 0.77 C7orf16chromosome 7 open reading frame 16 (ENSG00000106341), score: 0.69 CBLN1cerebellin 1 precursor (ENSG00000102924), score: 0.7 CBLN3cerebellin 3 precursor (ENSG00000139899), score: 0.71 CDH15cadherin 15, type 1, M-cadherin (myotubule) (ENSG00000129910), score: 0.81 CHD7chromodomain helicase DNA binding protein 7 (ENSG00000171316), score: 0.71 CHRNA3cholinergic receptor, nicotinic, alpha 3 (ENSG00000080644), score: 0.75 CNPY1canopy 1 homolog (zebrafish) (ENSG00000146910), score: 0.69 COL13A1collagen, type XIII, alpha 1 (ENSG00000197467), score: 0.81 CPLX4complexin 4 (ENSG00000166569), score: 0.79 CRTAMcytotoxic and regulatory T cell molecule (ENSG00000109943), score: 0.83 DUOX1dual oxidase 1 (ENSG00000137857), score: 0.72 EN2engrailed homeobox 2 (ENSG00000164778), score: 0.77 EOMESeomesodermin (ENSG00000163508), score: 0.7 EXPH5exophilin 5 (ENSG00000110723), score: 0.71 FAT2FAT tumor suppressor homolog 2 (Drosophila) (ENSG00000086570), score: 0.8 FGF17fibroblast growth factor 17 (ENSG00000158815), score: 0.69 FGF3fibroblast growth factor 3 (ENSG00000186895), score: 0.85 FGF5fibroblast growth factor 5 (ENSG00000138675), score: 0.73 GPRIN3GPRIN family member 3 (ENSG00000185477), score: 0.76 GRID2IPglutamate receptor, ionotropic, delta 2 (Grid2) interacting protein (ENSG00000215045), score: 0.8 GRM4glutamate receptor, metabotropic 4 (ENSG00000124493), score: 0.74 HINFPhistone H4 transcription factor (ENSG00000172273), score: 0.69 IFFO2intermediate filament family orphan 2 (ENSG00000169991), score: 0.69 IL16interleukin 16 (lymphocyte chemoattractant factor) (ENSG00000172349), score: 0.72 KIAA0802KIAA0802 (ENSG00000168502), score: 0.7 LBX1ladybird homeobox 1 (ENSG00000138136), score: 0.75 LHX5LIM homeobox 5 (ENSG00000089116), score: 0.69 LOC146429putative solute carrier family 22 member ENSG00000182157 (ENSG00000182157), score: 0.81 MAB21L1mab-21-like 1 (C. elegans) (ENSG00000180660), score: 0.79 MAML3mastermind-like 3 (Drosophila) (ENSG00000196782), score: 0.72 MAXMYC associated factor X (ENSG00000125952), score: 0.7 MDGA1MAM domain containing glycosylphosphatidylinositol anchor 1 (ENSG00000112139), score: 0.75 NHLH2nescient helix loop helix 2 (ENSG00000177551), score: 0.86 NKX6-3NK6 homeobox 3 (ENSG00000165066), score: 0.71 NRIP2nuclear receptor interacting protein 2 (ENSG00000053702), score: 0.73 NYNRINNYN domain and retroviral integrase containing (ENSG00000205978), score: 0.7 ODZ1odz, odd Oz/ten-m homolog 1(Drosophila) (ENSG00000009694), score: 0.71 OTX2orthodenticle homeobox 2 (ENSG00000165588), score: 0.87 PKIBprotein kinase (cAMP-dependent, catalytic) inhibitor beta (ENSG00000135549), score: 0.79 PRDM10PR domain containing 10 (ENSG00000170325), score: 0.75 PTCHD1patched domain containing 1 (ENSG00000165186), score: 0.7 PYDC1PYD (pyrin domain) containing 1 (ENSG00000169900), score: 0.77 RCAN3RCAN family member 3 (ENSG00000117602), score: 0.81 SLC35F4solute carrier family 35, member F4 (ENSG00000151812), score: 0.79 SPINK6serine peptidase inhibitor, Kazal type 6 (ENSG00000178172), score: 1 TAS2R3taste receptor, type 2, member 3 (ENSG00000127362), score: 0.7 TGM1transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) (ENSG00000092295), score: 0.72 TLL1tolloid-like 1 (ENSG00000038295), score: 0.74 TMC2transmembrane channel-like 2 (ENSG00000149488), score: 0.9 TP73tumor protein p73 (ENSG00000078900), score: 0.82 TRIM67tripartite motif-containing 67 (ENSG00000119283), score: 0.77 VSX1visual system homeobox 1 (ENSG00000100987), score: 0.9 XKR7XK, Kell blood group complex subunit-related family, member 7 (ENSG00000101321), score: 0.75 ZIC4Zic family member 4 (ENSG00000174963), score: 0.79 ZIC5Zic family member 5 (odd-paired homolog, Drosophila) (ENSG00000139800), score: 0.7 ZNF521zinc finger protein 521 (ENSG00000198795), score: 0.71
| Id | species | tissue | sex | individual |
|---|---|---|---|---|
| ppa_cb_m_ca1 | ppa | cb | m | _ |
| ggo_cb_f_ca1 | ggo | cb | f | _ |
| ptr_cb_m_ca1 | ptr | cb | m | _ |
| hsa_cb_m_ca1 | hsa | cb | m | _ |
| hsa_cb_f_ca1 | hsa | cb | f | _ |
